Alex Karczmar
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American neurosurgeon
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Medical Philosophy
Alex Karczmar's Degrees
- Doctorate Medicine Johns Hopkins University
- Masters Public Health Stanford University
Why Is Alex Karczmar Influential?
(Suggest an Edit or Addition)According to Wikipedia, Alexander George Karczmar , was a Polish-American neuroscientist and academic. He was tenured for 30 years as professor and chairman of the Department of Pharmacology and Experimental Therapeutics at Loyola University of Chicago Medical Center, and director of its Institute for Mind, Drugs and Behavior.
Alex Karczmar's Published Works
Published Works
- Anticholinesterase Agents. (1963) (494)
- Common mechanism of toxicity: a case study of organophosphorus pesticides. (1998) (447)
- Primary afferent neurones: the ionic mechanism of GABA-mediated depolarization. (1974) (176)
- A pharmacological model of paradoxical sleep: the role of cholinergic and monoamine systems. (1970) (158)
- Actions of substance P on sympathetic neurons (1979) (139)
- Brain and Human Behavior (1936) (105)
- Acute and long lasting central actions of organophosphorus agents. (1984) (85)
- Substance P: a putative sensory transmitter in mammalian autonomic ganglia. (1982) (79)
- Interdisciplinary approach to the study of behavior in related mice types. (1973) (64)
- C – Pharmacologic, Toxicologic, and Therapeutic Properties of Anticholinesterase Agents* (1967) (59)
- The presynaptic site of action of norepinephrine in the superior cervical ganglion of guinea pig. (1977) (57)
- Invited Review Anticholinesterases: dramatic aspects of their use and misuse (1998) (55)
- Brain catecholamines and serotonin levels in various strains and genera of mice and a possible interpretation for the correlations of amine levels with electroshock latency and behavior. (1966) (52)
- Effects of diisopropyl phosphorofluoridate on acetylcholine, cholinesterase and catecholamines of several parts of rabbit brain. (1974) (50)
- Alkaline phosphatase during limb development and regeneration of Amblystoma opacum and Amblystoma punctatum (1951) (47)
- Brief Presentation of the Story and Present Status of Studies of the Vertebrate Cholinergic System (1993) (45)
- Dopamine and adenosine 3',5'-monophosphate responses of single mammalian sympathetic neurons. (1977) (43)
- Exploitable Aspects of Central Cholinergic Functions, Particularly with Respect to the EEG, Motor, Analgesic and Mental Functions (1978) (43)
- Exploring the vertebrate central cholinergic nervous system (2006) (42)
- Substance P-induced depolarization in sympathetic neurons: not simple K-inactivation (1981) (41)
- The role of amputation and nerve resection in the regressing limbs of urodele larvae. (1946) (41)
- Cholinergic effects on adrenergic neurotransmitters in rabbit brain parts. (1972) (41)
- Alteration in nicotinic and muscarinic responses of rabbit superior cervical ganglion cells after chronic preganglionic denervation (1976) (39)
- Behavioural developmental studies on four genera and several strains of mice. (1967) (38)
- Blockade of ACh potentials by α-bungarotoxin in rat superior cervical ganglion cells (1980) (37)
- An analysis of the effect of angiotensin II on mammalian ganglion cells. (1978) (37)
- Di-isopropyl phosphofluoridate-induced antinociception: possible role of endogenous opioids. (1980) (37)
- Contribution to the study of the mechanism of action of cholinesterase inhibitors. (1951) (35)
- Cholinesterases (ChEs) and the cholinergic system in ontogenesis and phylogenesis, and non-classical roles of cholinesterases - a review. (2010) (35)
- Acetylcholine depolarization of the dorsal root nerve terminals in the amphibian spinal cord. (1969) (33)
- Evidence for a presynaptic inhibitory action of 5-hydroxytryptamine in a mammalian sympathetic ganglion. (1981) (32)
- Muscarinic and cGMP induced membrane potential changes: differences in electrogenic mechanisms (1978) (32)
- Ontogenesis of Cholinesterases (1963) (32)
- CONTRASTING BEHAVIORAL, PHARMACOLOGICAL, NEUROPHYSIOLOGICAL, AND BIOCHEMICAL PROFILES OF C57 B1/6 AND SC-I STRAINS OF MICE. (1963) (31)
- A comparison of the effect of theophylline and cyclic adenosine 3': 5'-monophosphate on the superior cervical ganglion of the rabbit by means of the sucrose-gap method. (1977) (29)
- Brain Acetylcholine and Animal Electrophysiology (1979) (29)
- Effect of diisopropyl phosphofluoridate on analgesia and motor behavior in the rat (1978) (28)
- Muscarinic and nicotinic stimulant actions at autonomic ganglia (1966) (27)
- Cholinergic substrates of cognition and organism-environment interaction (1995) (27)
- Autonomic and Enteric Ganglia (1986) (26)
- Activation of acetylcholinesterase by Triton X-100. (1972) (26)
- An effect of physostigmine on the central nervous system of rabbits, related to brain levels of norepinephrine. (1971) (26)
- Effects of anticholinesterases and of sodium fluoride on neuromyal desensitization (1980) (25)
- Antagonism between a bis-quaternary oxamide, Win 8078, and depolarizing and competitive blocking agents. (1957) (25)
- Effects of L-dopa on behavior and on brain amines in mice treated with 6-hydroxydopamine. (1973) (24)
- Adaptation of the neuromuscular junction to constant concentration of ACh. (1967) (24)
- MULTIPLE CHOLINOCEPTIVE AND RELATED SITES AT THE NEUROMUSCULAR JUNCTION (1967) (23)
- Autonomic and enteric ganglia : transmission and its pharmacology (1985) (23)
- The Otto Loewi Lecture. Loewi's discovery and the XXI century. (1996) (22)
- Neurobiology of Acetylcholine (1987) (22)
- Basic Phenomena Underlying Novel use of Cholinergic Agents, Anticholinesterases and Precursors in Neurological Including Peripheral and Psychiatric Disease (1981) (21)
- Involvement of an interneuron in the generation of the slow inhibitory postsynaptic potential in mammalian sympathetic ganglia. (1978) (21)
- Bernard B. Brodie and the rise of chemical pharmacology. (1989) (21)
- Neuropharmacological and related aspects of animal aggression (1978) (20)
- Electrical properties of the membrane of denervated mammalian sympathetic ganglion cells (1976) (20)
- Electrophysiology, acetylcholine and acetylcholinesterase of immature spinal ganglia of the rabbit--an experimental study and a review. (1980) (19)
- Rat brain acetylcholinesterase and its isoenzymes after intracerebral administration of DFP. (1976) (18)
- An evaluation of the pharmacologic actions of some bis-quaternary salts of basically substituted oxamides (WIN 8077 and analogs). (1955) (18)
- A direct facilitatory action for dopamine at the neuromuscular junction. (1973) (18)
- Direct postsynaptic membrane effect of dibutyryl cyclic GMP on mammalian sympathetic neurons (1977) (16)
- Neuromyopharmacology as related to anticholinesterase action. (1981) (16)
- Present and future of the development of anti-OP drugs. (1985) (16)
- Investigations, particularly by means of the anticholinesterase agents, of the multiple peripheral and central cholinergic mechanisms and of their behavioral implications. (1970) (15)
- Effect of Tetraethyl Pyrophosphate on Sympathetic Ganglionic Activity. (1947) (15)
- Facilitation and inhibition of nicotinic transmission by eserine in the sympathetic ganglia of the rabbit (1985) (15)
- Chapter 45 Physiological cholinergic functions in the CNS (1990) (15)
- Limb parameters and regression rates in denervated amputated limbs of urodele larvae (1944) (15)
- Endplate effects and antagonism to d-tubocurarine and decamethonium of tetraethylammonium and of methoxyambem (WIN 8078). (1961) (15)
- A comparative study of the pharmacological properties of the positive potential recorded from the superior cervical ganglia of several species. (1980) (14)
- Possible reactivating and sensitizing action of neuromyally acting agents. (1968) (13)
- Interaction between facilitating and depolarizing drugs at the neuromyal junction of the cat. (1967) (13)
- Effects of drugs on the tunicate (1963) (12)
- Temperature and regression rates in denervated amputated limbs of urodele larvae (1945) (12)
- Aggression and the orienting reflex in several genera and strains of mice. (1969) (12)
- Distribution of intravenously administered chlorpromazine in cat tissues (1963) (11)
- Drugs, transmitters and hormones, and mating behavior. (1980) (11)
- Correlation between pharmacological responses to benzoylcholine, methacholine and acetylcholine and activity of cholinesterases. (1953) (11)
- A study of avoidance conditioning in five genera of mice (1969) (11)
- Is the central cholinergic nervous system overexploited? (1969) (11)
- Putative transmitter systems of mammalian sympathetic preganglionic neurons. (1993) (10)
- Sir John Eccles, 1903-1997: Part 1. Onto the Demonstration of the Chemical Nature of Transmission in the CNS (2001) (10)
- Effects of serotonin (5-hydroxytryptamine) on amphibian neuromuscular junction. (1983) (10)
- Changes in transport cholinesterase levels and responses to intravenously administered acetylcholine and benzoylcholine. (1956) (10)
- Multiple Mechanisms in Ganglionic Transmission (1981) (10)
- Relationship between peripheral cholinolytic potency and tetraethylpyrophosphate antagonism of a series of atropine substitutes. (1958) (9)
- The mode of action of fluoride ions on neuromuscular transmission in frogs (1978) (9)
- Some observations on the actions of certain pharmacological agents on the fibrillation potentials and on the sensitivity of the skeletal muscle of rabbit in advanced local tetanus (1962) (9)
- PHARMACOLOGICAL ACTIONS OF OXAMIDES AND HYDROXYANILINIUM COMPOUNDS AT FROG NEUROMYAL JUNCTION. (1965) (9)
- Effect of iodoacetate on changes in muscular latency induced by activity. (1950) (8)
- Effects of cholinergic drugs on tunicate smooth muscle. (1966) (8)
- Toxicity arising from joint intravenous administration of EPN and malathion to dogs. (1962) (8)
- MULTITRANSMITTER MECHANISMS UNDERLYING SELECTED FUNCTION, PARTICULARLY AGGRESSION, LEARNING AND SEXUAL BEHAVIOR (1978) (8)
- Sir John Eccles, 1903-1997: Part 2: The Brain as a Machine or as a Site of Free Will? (2001) (8)
- The types and sites of cholinergic receptors. (1971) (7)
- Histochemical studies of cholinesterases in Ciona intestinalis. (1966) (7)
- Intergeneric behavioral differences among methamphetamine treated mice (2004) (7)
- Anticholinesterases and War Gases (2007) (7)
- SDAT Models and Their Dynamics (1991) (7)
- Historical Development of Concepts of Ganglionic Transmission (1986) (6)
- Cholinergic Mechanisms, Schizophrenia, and Neuropsychiatric Adaptive Dysfunctions (1985) (6)
- Theophylline preparations in the treatment of myasthenia gravis. (1971) (6)
- Conference on Dynamics of Cholinergic Function: Overview and Comments (1986) (6)
- Behavioral responses to drugs and brain catecholamine levels in mice of different strains and genera. (1967) (6)
- Physiological cholinergic functions in the CNS. (1990) (6)
- Relative Instability of Chlorpromazine in N Alkali (1958) (6)
- The action of ambenonium (WIN 8077) and related compounds in the mouse. (1957) (5)
- Physiology and Pharmacology of Ganglionic Synapses as Models for Central Transmission (1979) (5)
- The Chemical Coding Via the Cholinergic System: Its Organization and Behavioral Implications (1974) (5)
- Postsynaptic facilitatory effects of theophylline on amphibian neuromyal transmission. (1978) (5)
- Comments to session on electrophysiological aspects of cholinergic mechanisms. (1993) (5)
- Studies on intravenously injected true cholinesterase. (1951) (5)
- Introduction to the session on modulators (1987) (5)
- General Concepts of Ganglionic Transmission and Modulation (1986) (5)
- Comprar Exploring the Vertebrate Central Cholinergic Nervous System | Karczmar, Alexander G. | 9780387282237 | Springer (2007) (5)
- Pharmacologic actions at various neuroeffectors of single and combined administration of EPN and malathion (1963) (5)
- Effects of 1-methyl-3-isobutyl xanthine (MIX) on amphibian neuromyal transmission. (1980) (4)
- Blockade of ACh potentials by alpha-bungarotoxin in rat superior cervical ganglion cells. (1980) (4)
- Thrombin Induced Contraction Of Isolated Smooth Muscles (1981) (4)
- Further studies on intravenously injected cholinesterase preparations. (1953) (4)
- Acetylcholine turnover and aggression in related three strains of mice. (1981) (4)
- Antiaccelerator, Coronary Dilator and Certain Other Pharmacologic Actions of New Poly-Methoxyphenyl Derivatives (1958) (4)
- CNS effects of anticholinesterases in the presence of inhibited cholinesterases. (1978) (4)
- Quantitative colorimetric method and extraction procedure for determination of chlorpromazine in animal tissues (1963) (4)
- Pharmacology of Synaptic Ganglionic Transmission and Second Messengers (1986) (3)
- EFFECTS OF DRUGS ON THE TUNICATE ELECTROCARDIOGRAM. (1963) (3)
- Ganglionic Transmission as a Model for CNS Function (1986) (3)
- Story of Muscarinic Receptors, Alkaloids with Muscarinic Significance and of Muscarinic Functions and Behaviors (2009) (3)
- History of research on nicotinic and muscarinic cholinergic receptors (2007) (3)
- LIMB REGENERATION AND DIFFERENTIATION OF “OVERT BEHAVIOR” IN URODELES AS STUDIED BY MEANS OF THEIR RESPONSE TO CHEMICAL AGENTS (1955) (3)
- Do all Human Functions and Behaviors, as well as the “Self”, Have Cholinergic Correlates? (2009) (2)
- A century of synaptic transmission (2002) (2)
- Concluding Remarks: Past, Present and Future of Cholinergic Research (1987) (2)
- Neuromuscular pharmacology. (1967) (2)
- Conclusions and comments. Xth International Symposium on Cholinergic Mechanisms (1998) (2)
- The mechanism of the anti-desensitizing action of sodium fluoride at the amphibian neuromyal junction (1982) (2)
- Historical aspects of the cholinergic transmission. (1991) (2)
- Action of central nervous system depressants at different growth periods of salamander larvae. (1948) (2)
- Prophylactic and antidotal treatment of sarin poisoning with drugs given singly and in combination. (1968) (2)
- 496 Certain aspects of pharmacology of neuromyal cholinergic receptor (1961) (2)
- Action of central nervous system depressants at different growth periods of salamander (Amblystoma punctatum) larvae. (1948) (1)
- Effects of (+)-tubocurarine on neuromuscular facilitation and depression in rat diaphragm (1976) (1)
- Behavioral and pharmacological differences among certain strains of mice. Abstr. (1961) (1)
- Multiple mechanisms of action of drugs at the neuromyal junction as studied in the light of the phenomenon of "reversal". (1967) (1)
- RE-EVALUATION OF PHARMACOLOGICAL ACTIONS OF MYTOLON (1957) (1)
- The effect of stimulant drugs on overt behavior. (1947) (1)
- The Tenth International Symposium on Cholinergic Mechanisms, Arcachon, France September 1–5, 1998 (2006) (1)
- The effect of repeated amputation and blastema formation on regeneration. (1947) (1)
- Effects of psychopharmacologic agents on synaptic transmission in the hippocampus. (1962) (1)
- "Global" cerebral evoked potentials of the rat elicited by light flashes and behavior. (1967) (1)
- Conclusions and comments for the XII ISCM (2007) (1)
- Anticholinesterase and toxic effects of parathion (O-O-diethyl p-nitrophenyl thiophosphate). (1948) (1)
- Influence of methyl bis (B chloroethyl)amine (nitrogen mustard), hydroquinoneand thy-roxino on regeneration in Urodele larvae (1948) (1)
- Neurological, neurotransmitter, and pharmacological aspects of sexual behavior. (1975) (1)
- Pharmacology of a new bronchoconstrictor drug, hexaethyltetraphosphate. (1947) (1)
- Autonomic Disease and Clinical Applications of Ganglionic Agents (1986) (1)
- Physiological effects and probable fate of true cholinesterase. (1948) (0)
- The effects of lethal doses of acetanilid in the dog. (1947) (0)
- Milestones in the discovery and understanding of the brain cholinergic system (2006) (0)
- [Some aspects of the pharmacology of cholinergic synapses and its central significance]. (1969) (0)
- Central cholinergic transmission and its behavior aspects. Introductory remarks. (1969) (0)
- Combination donepezil and dihydroepiandrosterone therapy for post-stroke rehabilitation (2004) (0)
- Inhibition of bradykinin-induced contraction of isolated smooth muscle tissue preparations by oligopeptide thiobenzyl ester substrates for serine proteases. (1983) (0)
- SYNAPTIC TRANSMISSION IN THE HIPPOCAMPUS AND PSYCHOPHARMACOLOGICAL AGENTS. (1963) (0)
- Discussion of De Robertis’ Paper (1972) (0)
- Conclusions and comments: XI ISCM (2004) (0)
- Discussion of Kety’s Paper (1972) (0)
- The XII International Symposium on Cholinergic Mechanisms (2006) (0)
- Cholinergic Behaviors, Emotions, and the “Self” (2013) (0)
- Cholinergic Behaviors, Emotions, and the “Self” (2014) (0)
- The effect of depressant drugs on overt behavior. (1947) (0)
- Drug action on the central nervous system during the development of urodele larvae. (1958) (0)
- [Use of lipiodol-ether mixture in hysterosalpingography; clinical, experimental, and bacteriologic studies]. (1952) (0)
- 293 – EFFECTS OF CYCLIC NUCLEOTIDES ON THE ELECTROGENESIS OF SLOW SYNAPTIC POTENTIALS IN THE MAMMALIAN SYMPATHETIC GANGLION CELLS (1978) (0)
- Rauhsche Nase—Then and Now (1993) (0)
- SUMMARY OF THE SESSION (1978) (0)
- Pharmacological methods in the study of overt behavior. (1947) (0)
- Discussion of Beritashvili’s Paper (1972) (0)
- Neurophysiological and behavioral aspects of psychotropic drugs (1969) (0)
- The effects of di-isopropyl fluorophosphate and physostigmine on the sympathetic ganglia. (1947) (0)
- 1312 – PHYSIOLOGY AND PHARMACOLOGY OF GANGLIONIC SYNAPSES AS MODELS FOR CENTRAL TRANSMISSION (1978) (0)
- Frontiers in neuropharmacology. Introduction to the session on modulators. (1987) (0)
- Comparison of anesthetic action of acetanilid, tricaine and aliphatic depressants. (1948) (0)
- Discussion of Jouvet’s Paper (1972) (0)
- 537 – EFFECTS OF DIISOPROPYLPHOSPHOFLURIDATE (DFP) ON PAIN THRESHOLD AND SEROTONIN (1978) (0)
- XIV ISCM, Hangzhou, China, May 2013: Opening Remarks (2013) (0)
- Serotonin and a Role in the Modulation of Cholinergic Transmission in the Mammalian Prevertebral Ganglia (1986) (0)
- Discussion on Hydén’s Paper (1972) (0)
- Central effects of diisopropyl-fluorophosphonate (D.F.P.) in Urodele Larvae (2004) (0)
- Editorial board (1986) (0)
- Influence of methyl bis amine, hydroquinone and thyroxin on regeneration in urodele larvae. (1948) (0)
- Brain Mechanisms and Behaviour. An Outline of the Mechanisms of Emotion, Memory, Learning and the Organization of Behaviour, with Particular Regard to the Limbic System.J. R. Smythies (1971) (0)
- XIV ISCM, Hangzhou, China, May 2013: Opening Remarks (2014) (0)
- Obituary: Syogoro Nishi: 1929 – 2014 (2014) (0)
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