Alexander Markham
#21,741
Most Influential Person Now
British molecular biologist
Alexander Markham's AcademicInfluence.com Rankings
Alexander Markhambiology Degrees
Biology
#2232
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#3571
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Cell Biology
#121
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#126
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Genetics
#199
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#243
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Molecular Biology
#378
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#385
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Biology
Alexander Markham's Degrees
- PhD Molecular Biology University of Oxford
Why Is Alexander Markham Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sir Alexander Fred Markham, born 1950, is Professor of Medicine at the University of Leeds, Director of the Molecular Medicine Institute at St James's University Hospital, and a former Chief Executive of Cancer Research UK.
Alexander Markham's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). (1989) (2464)
- Sequence requirements for nuclear location of simian virus 40 large-T antigen (1984) (1178)
- Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. (1991) (772)
- A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. (1990) (651)
- Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells. (2002) (633)
- ASPM is a major determinant of cerebral cortical size (2002) (550)
- Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease (2001) (485)
- Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis (1999) (467)
- Levobupivacaine: a review of its pharmacology and use as a local anaesthetic. (2000) (444)
- Identification of microcephalin, a protein implicated in determining the size of the human brain. (2002) (433)
- Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions (2003) (370)
- Ciprofloxacin. An updated review of its pharmacology, therapeutic efficacy and tolerability. (1996) (335)
- Valsartan. A review of its pharmacology and therapeutic use in essential hypertension. (1997) (321)
- Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). (2001) (282)
- Identification of SATB2 as the cleft palate gene on 2q32-q33. (2003) (273)
- mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification (1983) (270)
- Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy (2008) (265)
- EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle (1998) (247)
- A 3.5 genome equivalent multi access YAC library: construction, characterisation, screening and storage. (1990) (220)
- Infliximab: a review of its use in the management of rheumatoid arthritis. (2000) (218)
- Reduced expression of oestrogen receptor β in invasive breast cancer and its re‐expression using DNA methyl transferase inhibitors in a cell line model (2003) (215)
- Ropivacaine : A Review of its Pharmacology and Therapeutic Use in Regional Anaesthesia. (1996) (205)
- Cyclosporin. A review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (Neoral). (1995) (201)
- Sildenafil: a review of its use in erectile dysfunction. (1999) (198)
- Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex (1984) (190)
- Mutations in TSPAN12 cause autosomal-dominant familial exudative vitreoretinopathy. (2010) (180)
- Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase. (1983) (176)
- Spectrum, frequency and penetrance of OPA1 mutations in dominant optic atrophy. (2001) (169)
- Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis. (2002) (169)
- beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects. (1984) (165)
- Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications. (1996) (164)
- Interactive visual analysis of SNP data for rapid autozygosity mapping in consanguineous families (2006) (160)
- Primary autosomal recessive microcephaly (MCPH1) maps to chromosome 8p22-pter. (1998) (159)
- Mycophenolate mofetil. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in renal transplantation. (1996) (158)
- Ganciclovir. An update of its therapeutic use in cytomegalovirus infection. (1994) (156)
- Genotype/phenotype correlations for coagulation factor XIII: specific normal polymorphisms are associated with high or low factor XIII specific activity. (1999) (153)
- Mirtazapine: a review of its use in major depression. (1999) (152)
- Isolation of cDNA clones for the human complement protein factor B, a class III major histocompatibility complex gene product. (1982) (145)
- Macrophage migration inhibitory factor promotes intestinal tumorigenesis. (2005) (144)
- Sumatriptan. An updated review of its use in migraine. (1998) (142)
- Quantification of the close association between DNA haplotypes and specific β-thalassaemia mutations in Mediterraneans (1984) (141)
- Finasteride: a review of its use in male pattern hair loss. (1999) (138)
- Regulation and function of the interaction between the APC tumour suppressor protein and EB1 (2000) (135)
- Irbesartan. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in the management of hypertension. (1997) (133)
- Camrelizumab: First Global Approval (2019) (132)
- Immunohistochemical Detection of the Anti-Apoptosis Protein, Survivin, Predicts Survival After Curative Resection of Stage II Colorectal Carcinomas (2001) (131)
- Ketohexokinase: Expression and Localization of the Principal Fructose-metabolizing Enzyme (2009) (129)
- BDNF increases rat brain mitochondrial respiratory coupling at complex I, but not complex II (2004) (126)
- The Ubiquitin-conjugating Enzymes UbcH7 and UbcH8 Interact with RING Finger/IBR Motif-containing Domains of HHARI and H7-AP1* (1999) (125)
- Alpelisib: First Global Approval (2019) (125)
- Deflazacort. A review of its pharmacological properties and therapeutic efficacy. (1995) (123)
- Nicorandil. An updated review of its use in ischaemic heart disease with emphasis on its cardioprotective effects. (2000) (121)
- Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin. (2003) (121)
- Total synthesis of a human leukocyte interferon gene (1981) (118)
- Irinotecan. A review of its pharmacological properties and clinical efficacy in the management of advanced colorectal cancer. (1996) (118)
- Direct detection of the common Mediterranean beta-thalassemia gene with synthetic DNA probes. An alternative approach for prenatal diagnosis. (1983) (110)
- Fcgamma receptor type IIIA is associated with rheumatoid arthritis in two distinct ethnic groups. (2000) (109)
- Fludarabine. An update of its pharmacology and use in the treatment of haematological malignancies. (1997) (109)
- Cemiplimab: First Global Approval (2018) (108)
- A novel mutation in the mitochondrial tRNASer(UCN) gene in a family with non-syndromic sensorineural hearing impairment (2000) (107)
- Isolation of a cDNA clone for human antithrombin III. (1983) (107)
- The second locus for autosomal recessive primary microcephaly (MCPH2) maps to chromosome 19q13.1–13.2 (1999) (106)
- Anti-oxazolone hybridomas and the structure of the oxazolone idiotype. (1983) (106)
- Terbinafine. An update of its use in superficial mycoses. (1999) (105)
- Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc(Min/+) mouse. (2001) (101)
- Diagnosis of alpha 1-antitrypsin deficiency by enzymatic amplification of human genomic DNA and direct sequencing of polymerase chain reaction products. (1988) (100)
- Inferring relative proportions of DNA variants from sequencing electropherograms (2009) (98)
- Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa (2002) (98)
- Baricitinib: First Global Approval (2017) (98)
- Human adenosine deaminase. cDNA and complete primary amino acid sequence. (1984) (96)
- Pamidronate. A review of its use in the management of osteolytic bone metastases, tumour-induced hypercalcaemia and Paget's disease of bone. (1998) (94)
- Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome (1997) (94)
- Copanlisib: First Global Approval (2017) (93)
- Ondansetron. An update of its therapeutic use in chemotherapy-induced and postoperative nausea and vomiting. (1993) (91)
- Brain‐derived neurotrophic factor‐mediated effects on mitochondrial respiratory coupling and neuroprotection share the same molecular signalling pathways (2012) (90)
- Genetic diagnosis of familial breast cancer using clonal sequencing (2010) (89)
- Use of a cDNA clone for the fourth component of human complement (C4) for analysis of a genetic deficiency of C4 in guinea pig. (1983) (89)
- Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD) (2011) (89)
- Delayed umbilical bleeding--a presenting feature for factor XIII deficiency: clinical features, genetics, and management. (2002) (87)
- Indomethacin induces differential expression of β-catenin, γ-catenin and T-cell factor target genes in human colorectal cancer cells (2002) (87)
- Prostate-specific membrane antigen. (1998) (87)
- The isolation and characterization of cDNA clones for human apolipoprotein CII. (1984) (86)
- Cerliponase Alfa: First Global Approval (2017) (84)
- Direct haplotype determination by double ARMS: specificity, sensitivity and genetic applications (1991) (84)
- Montelukast: a review of its therapeutic potential in persistent asthma. (2000) (83)
- Lack of association between 5-HT2A gene promoter polymorphism and susceptibility to anorexia nervosa (1998) (83)
- AMPLIFICATION REFRACTORY MUTATION SYSTEM FOR PRENATAL DIAGNOSIS AND CARRIER ASSESSMENT IN CYSTIC FIBROSIS (1989) (83)
- Isolation of human C-reactive protein complementary DNA and localization of the gene to chromosome 1. (1983) (83)
- Rapid synthesis of oligodeoxyribonucleotides. IV. Improved solid phase synthesis of oligodeoxyribonucleotides through phosphotriester intermediates. (1980) (83)
- Danaparoid. A review of its pharmacology and clinical use in the management of heparin-induced thrombocytopenia. (1998) (82)
- Expanding 3D geometry for enhanced on-chip microbubble production and single step formation of liposome modified microbubbles. (2012) (82)
- Features of the Parkin/Ariadne-like Ubiquitin Ligase, HHARI, That Regulate Its Interaction with the Ubiquitin-conjugating Enzyme, UbcH7* (2001) (81)
- A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity. (2005) (80)
- Changes in mitochondrial function are pivotal in neurodegenerative and psychiatric disorders: How important is BDNF? (2014) (79)
- Orlistat: a review of its use in the management of obesity. (1999) (79)
- Structure of the human aldose reductase gene. (1991) (77)
- Analysis of the serotonin transporter gene linked polymorphism (5-HTTLPR) in anorexia nervosa. (2000) (77)
- Molecular basis of inherited factor XIII deficiency: identification of multiple mutations provides insights into protein function (1995) (76)
- Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia (2004) (75)
- Pramipexole. A review of its use in the management of early and advanced Parkinson's disease. (1998) (75)
- Isolation of cDNA clones using yeast artificial chromosome probes (1990) (74)
- Atezolizumab: First Global Approval (2016) (73)
- Brigatinib: First Global Approval (2017) (73)
- Idelalisib: First Global Approval (2014) (73)
- Highly polymorphic minisatellite sequences: allele frequencies and mutation rates for five locus-specific probes in a Caucasian population. (1990) (72)
- Investigation of chromosome 9q22.3-q31 DNA marker loss in odontogenic keratocysts. (1996) (70)
- Engineering Gold Nanotubes with Controlled Length and Near‐Infrared Absorption for Theranostic Applications (2015) (69)
- A family study and the natural history of prenatally detected unilateral multicystic dysplastic kidney. (2002) (69)
- Luseogliflozin: First Global Approval (2014) (68)
- Prostaglandin transporter mutations cause pachydermoperiostosis with myelofibrosis (2012) (68)
- Identification of a point mutation in the adenosine deaminase gene responsible for immunodeficiency. (1985) (68)
- Sparfloxacin. A review of its antibacterial activity, pharmacokinetic properties, clinical efficacy and tolerability in lower respiratory tract infections. (1997) (67)
- Sequence analysis and editing for bisulphite genomic sequencing projects (2007) (66)
- Obeticholic Acid: First Global Approval (2016) (65)
- Transforming activity of polyoma virus middle-T antigen probed by site-directed mutagenesis (1983) (64)
- Belantamab Mafodotin: First Approval (2020) (64)
- Ropivacaine. A review of its pharmacology and therapeutic use in regional anaesthesia. (1996) (61)
- Erdafitinib: First Global Approval (2019) (61)
- Fluvastatin: a review of its use in lipid disorders. (1999) (61)
- Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy. (2016) (61)
- Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders (2004) (60)
- Brolucizumab: First Approval (2019) (59)
- Selpercatinib: First Approval (2020) (58)
- Fenoldopam: a review of its pharmacodynamic and pharmacokinetic properties and intravenous clinical potential in the management of hypertensive urgencies and emergencies. (1997) (57)
- Human tenascin‐C: Identification of a novel type III repeat in oral cancer and of novel splice variants in normal, malignant and reactive oral mucosae (1997) (57)
- Association between a marker in the UCP-2/UCP-3 gene cluster and genetic susceptibility to anorexia nervosa (1999) (56)
- HEATR2 Plays a Conserved Role in Assembly of the Ciliary Motile Apparatus (2014) (56)
- The presence of multiple regions of homozygous deletion at the CSMD1 locus in oral squamous cell carcinoma question the role of CSMD1 in head and neck carcinogenesis (2003) (56)
- Migalastat: First Global Approval (2016) (56)
- Molecular cloning of human adenosine deaminase gene sequences. (1983) (56)
- A gene for ataxic cerebral palsy maps to chromosome 9p12–q12 (2000) (55)
- Piperacillin/Tazobactam (1999) (55)
- A yeast artificial chromosome contig encompassing the cystic fibrosis locus. (1991) (55)
- Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis. (2004) (55)
- Mycophenolate Mofetil (1996) (55)
- Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP (2003) (53)
- Autozygosity Mapping with Exome Sequence Data (2013) (53)
- Setmelanotide: First Approval (2021) (53)
- A gene for autosomal recessive symmetrical spastic cerebral palsy maps to chromosome 2q24-25. (1999) (52)
- FcγRIIIA‐158V and rheumatoid arthritis: a confirmation study (2003) (52)
- Epoetin alfa. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in nonrenal applications. (1995) (51)
- Romosozumab: First Global Approval (2019) (51)
- On-chip preparation of nanoscale contrast agents towards high-resolution ultrasound imaging. (2016) (51)
- Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy. (2001) (50)
- A new locus for non-syndromal, autosomal recessive, sensorineural hearing loss (DFNB16) maps to human chromosome 15q21-q22. (1997) (50)
- Highly polymorphic minisatellite DNA probes. Further evaluation for individual identification and paternity testing. (1990) (50)
- Rabeprazole: a review of its use in acid-related gastrointestinal disorders. (1999) (49)
- Analysis of Fcγ receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B (2005) (48)
- Tavaborole: First Global Approval (2014) (48)
- Common and recurrent HPGD mutations in Caucasian individuals with primary hypertrophic osteoarthropathy. (2010) (47)
- Linkage studies of non-syndromic recessive deafness (NSRD) in a family originating from the Mirpur region of Pakistan maps DFNB1 centromeric to D13S175. (1996) (47)
- Genetic predisposition to fracture non-union: a case control study of a preliminary single nucleotide polymorphisms analysis of the BMP pathway (2011) (47)
- Theophylline. A review of its potential steroid sparing effects in asthma. (1998) (47)
- Fostamatinib: First Global Approval (2018) (47)
- Pralsetinib: First Approval (2020) (47)
- Vectorette PCR isolation of microsatellite repeat sequences using anchored dinucleotide repeat primers. (1996) (46)
- Peficitinib: First Global Approval (2019) (46)
- Both isoforms of ketohexokinase are dispensable for normal growth and development. (2010) (46)
- The Open Reading Frame 57 Gene Product of Herpesvirus Saimiri Shuttles between the Nucleus and Cytoplasm and Is Involved in Viral RNA Nuclear Export (1999) (45)
- The mechanism of inhibition of mitochondrial oxidative phosphorylation by the nonsteroidal anti-inflammatory agent diflunisal. (1983) (45)
- The isolation of cDNA clones for human apolipoprotein E and the detection of apoE RNA in hepatic and extra‐hepatic tissues. (1983) (45)
- Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. (2002) (45)
- Selumetinib: First Approval (2020) (44)
- REGN-EB3: First Approval (2021) (44)
- Ibutilide. A review of its pharmacological properties and clinical potential in the acute management of atrial flutter and fibrillation. (1997) (44)
- Oral delayed-release mesalazine: a review of its use in ulcerative colitis and Crohn's disease. (1999) (43)
- Irbesartan: an updated review of its use in cardiovascular disorders. (2000) (43)
- Suggestive evidence for genetic linkage between IgE phenotypes and chromosome 14q markers. (1999) (42)
- Molecular characterisation of three alpha-1-antitrypsin deficiency variants: proteinase inhibitor (Pi) nullcardiff (Asp256→Val); Pi Mmalton (Phe51→ deletion) and Pi I (Arg39→Cys) (1989) (42)
- Simple Detection of Germline Microsatellite Instability for Diagnosis of Constitutional Mismatch Repair Cancer Syndrome (2013) (42)
- Paracrine cyclooxygenase-2-mediated signalling by macrophages promotes tumorigenic progression of intestinal epithelial cells (2002) (41)
- Erenumab: First Global Approval (2018) (41)
- Ertugliflozin: First Global Approval (2018) (40)
- The polymerase chain reaction: a tool for molecular medicine. (1993) (40)
- The gene product encoded by ORF 57 of herpesvirus saimiri regulates the redistribution of the splicing factor SC-35. (1999) (40)
- Sub‐Nanometer Thick Gold Nanosheets as Highly Efficient Catalysts (2019) (39)
- Cytogenetic alterations in ovarian clear cell carcinoma detected by comparative genomic hybridisation (2003) (39)
- Acalabrutinib: First Global Approval (2017) (39)
- Genetic heterogeneity and HOMOG analysis in British malignant hyperthermia families. (1998) (39)
- Delafloxacin: First Global Approval (2017) (39)
- Erratum to: Nimesulide: an update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy (1994) (39)
- HACE1 deficiency causes an autosomal recessive neurodevelopmental syndrome (2015) (38)
- Guselkumab: First Global Approval (2017) (37)
- Site-directed mutagenesis of polyomavirus middle-T antigen sequences encoding tyrosine 315 and tyrosine 250 (1986) (37)
- Mutations around the NG59 lesion indicate an active association of polyoma virus middle‐T antigen with pp60c‐src is required for cell transformation. (1986) (37)
- Chemical synthesis of a human interferon-α2, gene and its expression in Escherichia coli (1983) (36)
- Genetic events during the transformation of a tamoxifen-sensitive human breast cancer cell line into a drug-resistant clone. (2001) (36)
- Bempedoic Acid: First Approval (2020) (35)
- MethylViewer: computational analysis and editing for bisulfite sequencing and methyltransferase accessibility protocol for individual templates (MAPit) projects (2010) (34)
- The carboxy terminus of the herpesvirus saimiri ORF 57 gene contains domains that are required for transactivation and transrepression. (2000) (34)
- Characterisation and expression of Sox9 in the Leopard gecko, Eublepharis macularius. (2001) (34)
- Dofetilide: a review of its use in atrial fibrillation and atrial flutter. (1999) (33)
- A Moroccan family with autosomal recessive sensorineural hearing loss caused by a mutation in the gap junction protein gene connexin 26 (GJB2). (1998) (33)
- Analysis of Gene Expression in a Human Cell Line Stably Transduced with Herpesvirus Saimiri (2000) (33)
- Molecular Analysis of the Presenilin 1 (S182) Gene in “Sporadic” Cases of Alzheimer's Disease: Identification and Characterisation of Unusual Splice Variants (1996) (33)
- Human glucokinase regulatory protein (GCKR): cDNA and genomic cloning, complete primary structure, and chromosomal localization (1995) (32)
- Segregation of malignant hyperthermia, central core disease and chromosome 19 markers. (1999) (32)
- Solid phase phosphotriester synthesis of large oligodeoxyribonucleotides on a polyamide support. (1980) (32)
- Dynamics of cruciform extrusion in supercoiled DNA: use of a synthetic inverted repeat to study conformational populations. (1983) (32)
- IBDfinder and SNPsetter: Tools for pedigree‐independent identification of autozygous regions in individuals with recessive inherited disease (2009) (32)
- Regulation of stromal cell cyclooxygenase-2 in the ApcMin/+ mouse model of intestinal tumorigenesis. (2006) (32)
- Characterization of the herpesvirus saimiri ORF73 gene product. (2000) (32)
- Dostarlimab: First Approval (2021) (32)
- The Activation Domain of Herpesvirus Saimiri R Protein Interacts with the TATA-Binding Protein (1999) (32)
- Teprotumumab: First Approval (2020) (31)
- Tepotinib: First Approval (2020) (31)
- Roxithromycin. An update of its antimicrobial activity, pharmacokinetic properties and therapeutic use. (1994) (31)
- Lurbinectedin: First Approval (2020) (31)
- Molecular analysis of sixteen unrelated factor XIIIA deficient families from south‐east of Iran (2008) (30)
- Action of the nonsteroidal anti-inflammatory agent, flufenamic acid, on calcium movements in isolated mitochondria. (1988) (30)
- Telotristat Ethyl: First Global Approval (2017) (30)
- PAX 6 is normal in most cases of Peters' anomaly (1998) (30)
- Reslizumab: First Global Approval (2016) (30)
- Autozygosity mapping, to chromosome 11q25, of a rare autosomal recessive syndrome causing histiocytosis, joint contractures, and sensorineural deafness. (1998) (29)
- Prolonged-release mesalazine: a review of its therapeutic potential in ulcerative colitis and Crohn's disease. (2000) (29)
- Relugolix: First Global Approval (2019) (29)
- Assessment of Herpesvirus saimiri as a potential human gene therapy vector (1999) (28)
- Savolitinib: First Approval (2021) (28)
- Siltuximab: First Global Approval (2014) (28)
- Joining of synthetic ribotrinucleotides with defined sequences catalyzed by T4 RNA ligase. (1977) (28)
- Molecular biology of prostate cancer (2004) (27)
- Bictegravir: First Global Approval (2018) (27)
- Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues (2020) (27)
- Fine-mapping, genomic organization, and transcript analysis of the human ubiquitin-conjugating enzyme gene UBE2L3. (1998) (27)
- PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein. (2004) (27)
- Total synthesis of a RNA molecule with sequence identical to that of Escherichia coli formylmethionine tRNA. (1981) (27)
- Cabotegravir Plus Rilpivirine: First Approval (2020) (27)
- Tisotumab Vedotin: First Approval (2021) (27)
- Sotagliflozin: First Global Approval (2019) (27)
- Ofloxacin otic solution: a review of its use in the management of ear infections. (1999) (26)
- Inhaled salmeterol/fluticasone propionate combination. A pharmacoeconomic review of its use in the management of asthma. (2000) (26)
- Maternally inherited hearing impairment in a family with the mitochondrial DNA A7445G mutation (2001) (26)
- The cellular distribution of the adenomatous polyposis coli tumour suppressor protein in neuroblastoma cells is regulated by microtubule dynamics (1997) (26)
- Bezlotoxumab: First Global Approval (2016) (26)
- Evinacumab: First Approval (2021) (26)
- Metoprolol: a review of its use in chronic heart failure. (2000) (26)
- The influence of intercalating perfluorohexane into lipid shells on nano and microbubble stability. (2016) (25)
- Direct Detection of the Common Mediterranean (1983) (25)
- Naxitamab: First Approval (2021) (25)
- Cefixime. A review of its therapeutic efficacy in lower respiratory tract infections. (1995) (25)
- New Splicing Mutations in the Human Factor XIIIA Gene, Each Producing Multiple Mutant Transcripts of Varying Abundance (1998) (25)
- Ibalizumab: First Global Approval (2018) (25)
- A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development (2017) (24)
- Oritavancin: First Global Approval (2014) (24)
- Organization of the human glucokinase regulator gene GCKR. (1998) (24)
- OVA: integrating molecular and physical phenotype data from multiple biomedical domain ontologies with variant filtering for enhanced variant prioritization (2015) (24)
- Analysis of the mismatch and insertion/deletion binding properties of Thermus thermophilus, HB8, MutS. (1997) (24)
- Danoprevir: First Global Approval (2018) (24)
- The construction of a synthetic Escherichia coli trp promoter and its use in the expression of a synthetic interferon gene. (1982) (24)
- Benralizumab: First Global Approval (2018) (24)
- Prenatal diagnosis of aniridia. (2000) (24)
- Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis (2003) (24)
- GeneTIER: prioritization of candidate disease genes using tissue-specific gene expression profiles (2015) (24)
- Mutation in ferritin light chain causes dominant adult onset neurodegeneration (2001) (24)
- m6aViewer: software for the detection, analysis, and visualization of N6-methyladenosine peaks from m6A-seq/ME-RIP sequencing data (2017) (24)
- Naldemedine: First Global Approval (2017) (24)
- GeneScreen: a program for high-throughput mutation detection in DNA sequence electropherograms (2010) (24)
- The human aldose reductase gene maps to chromosome region 7q35 (1991) (23)
- Ixekizumab: First Global Approval (2016) (23)
- Fexofenadine (2019) (23)
- Expression of β-catenin and the adenomatous polyposis coli tumour suppressor protein in mouse neocortical cells in vitro (1997) (23)
- Factor XIII Deficiency Causing Mutation, Ser295Arg, in Exon 7 of the Factor XIIIA Gene (2000) (23)
- Current status of linkage studies in hereditary prostate cancer (2000) (22)
- Isolation and characterisation of a cDNA encoding the precursor for a novel member of the acyl-CoA dehydrogenase gene family. (1999) (22)
- Inhaled salmeterol/fluticasone propionate combination: a review of its use in persistent asthma. (2000) (22)
- Primary Hypertrophic Osteoarthropathy: An Update on Patient Features and Treatment (2015) (22)
- The Leu564 Factor XIIIA Variant Results in Significantly Lower Plasma Factor XIII Levels than the Pro564 Variant (1999) (22)
- Telmisartan (2020) (22)
- CCR7 (EBI1) receptor down-regulation in asthma: differential gene expression in human CD4+ T lymphocytes. (1999) (22)
- Genetic heterogeneity in Schwartz-Jampel syndrome: two families with neonatal Schwartz-Jampel syndrome do not map to human chromosome 1p34-p36.1. (1997) (21)
- Vadadustat: First Approval (2020) (21)
- Identification of a large deletion, spanning exons 4 to 11 of the human factor XIIIA gene, in a factor XIII-deficient family. (1998) (21)
- Oliceridine: First Approval (2020) (21)
- Epoetin beta. A review of its pharmacological properties and clinical use in the management of anaemia associated with chronic renal failure. (1996) (21)
- A deletion mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) locus: Delta I507. (1991) (21)
- Pamiparib: First Approval (2021) (20)
- Specific oncolytic activity of herpesvirus saimiri in pancreatic cancer cells (2000) (20)
- Remogliflozin Etabonate: First Global Approval (2019) (20)
- A herpesvirus saimiri-based gene therapy vector with potential for use in cancer immunotherapy (2000) (20)
- Ion-exchange high-performance liquid chromatography of oligodeoxyribonucleotides using formamide. (1983) (20)
- Nucleotide sequence of cDNA for human aldose reductase. (1989) (20)
- Gene K of bacteriophage phi X174 codes for a protein which affects the burst size of phage production (1985) (20)
- Lisinopril. A review of its pharmacology and clinical efficacy in elderly patients. (1997) (20)
- Evidence for a role of HLA DRB1 alleles in the control of IgE levels, strengthened by interacting TCR A/D marker alleles (2000) (19)
- Application of differential display to immunological research. (2001) (19)
- Evidence for a common mutation in hereditary pancreatitis. (1998) (19)
- Detection by fluorescence in situ hybridization of microdeletions at 1p36 in lymphomas, unidentified on cytogenetic analysis. (2003) (19)
- The production of PCR products with 5' single-stranded tails using primers that incorporate novel phosphoramidite intermediates. (1993) (19)
- FcgammaRIIIA-158V and rheumatoid arthritis: a confirmation study. (2003) (19)
- Palmitoyl carnitine: an endogenous promotor of calcium efflux from rat heart mitochondria. (1988) (19)
- Rapid chemical synthesis and circular dichroism properties of some 2'-5'-linked oligoriboadenylates. (1979) (19)
- Tildrakizumab: First Global Approval (2018) (19)
- Spectral evidence for the presence of cytochrome P-450 in microsomal fractions obtained from some higher plants. (1972) (18)
- Increased elafin expression in cystic, dysplastic and neoplastic oral tissues. (1996) (18)
- Genetic screening in a large family with juvenile onset primary open angle glaucoma (2000) (18)
- The CD4+ T lymphocyte is a site of steroid resistance in asthma. (1998) (18)
- The effects of cadmium on succinate and NADH‐linked substrate oxidations in rat hepatic mitochondria (1986) (18)
- Pimavanserin: First Global Approval (2016) (18)
- Vericiguat: First Approval (2021) (18)
- Pergolide : A Review of its Pharmacology and Therapeutic Use in Parkinson's Disease. (1997) (18)
- No polymorphism in the tissue transglutaminase gene detected in coeliac disease patients. (2000) (18)
- Prolonged-Release Mesalazine (2000) (18)
- Paracrine cyclooxygenase-2 activity by macrophages drives colorectal adenoma progression in the ApcMin/+ mouse model of intestinal tumorigenesis (2017) (18)
- Linkage/association study of a locus modulating total serum IgE on chromosome 14q13–24 in families with asthma (2004) (17)
- Molecular characterisation of two alpha-1-antitrypsin deficiency variants: proteinase inhibitor (Pi) NullNewport (Gly115→Ser) and (Pi) Z Wrexham (Ser−19→Leu) (1990) (17)
- Oral Delayed-Release Mesalazine (1999) (17)
- Darolutamide: First Approval (2019) (17)
- A syndrome of severe mental retardation, spasticity, and tapetoretinal degeneration linked to chromosome 15q24. (1998) (16)
- Mobocertinib: First Approval (2021) (16)
- An observational study on the expression levels of MDM2 and MDMX proteins, and associated effects on P53 in a series of human liposarcomas (2013) (16)
- Isolation and characterisation of a cDNA clone for human apolipoprotein CI and assignment of the gene to chromosome 19 (2004) (16)
- Tenapanor: First Approval (2019) (16)
- Automated differential display using a fluorescently labeled universal primer. (1997) (16)
- Luspatercept: First Approval (2020) (16)
- Mibefradil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of hypertension and angina pectoris. (1997) (16)
- Rapid determination of the complexity of cDNA bands extracted from DDRT-PCR polyacrylamide gels. (1997) (16)
- Epoetin Alfa (1995) (16)
- Joining of 3'-modified oligonucleotides by T4 RNA ligase. Synthesis of a heptadecanucleotide corresponding to the bases 61--77 from Escherichia coli tRNAfMet. (1978) (16)
- Clarithromycin and omeprazole as helicobacter pylori eradication therapy in patients with H. pylori-associated gastric disorders. (1996) (16)
- Genetic heterogeneity for recessively inherited congenital cataract microcornea with corneal opacity. (2011) (15)
- Splicing and missense mutations in the human FXIIIA gene causing FXIII deficiency: effects of these mutations on FXIIIA RNA processing and protein structure (1998) (15)
- Walking, cloning, and mapping with yeast artificial chromosomes: a contig encompassing D21S13 and D21S16. (1992) (15)
- Solriamfetol: First Global Approval (2019) (15)
- Assignment1 of GALGT encoding β-1,4N-acetylgalactosaminyl-transferase (GalNAc-T) and KIF5A encoding neuronal kinesin (D12S1889) to human chromosome band 12q13 by assignment to ICI YAC 26EG10 and in situ hybridization (1998) (15)
- Molecular genetic analysis of the human sorbitol dehydrogenase gene (1995) (15)
- Development of orthotopic tumour models using ultrasound-guided intrahepatic injection (2019) (15)
- Omadacycline: First Global Approval (2018) (15)
- Co-localization of the ketohexokinase and glucokinase regulator genes to a 500-kb region of Chromosome 2p23 (1996) (15)
- Tirbanibulin: First Approval (2021) (15)
- Evolocumab: First Global Approval (2015) (15)
- The use of fluorescent in situ hybridization for detection of the t(2;5)(p23;q35) translocation in anaplastic large-cell lymphoma. (1997) (15)
- Rapid Detection of Rare Deleterious Variants by Next Generation Sequencing with Optional Microarray SNP Genotype Data (2015) (15)
- Elotuzumab: First Global Approval (2016) (15)
- One‐Step Preparation of Biocompatible Gold Nanoplates with Controlled Thickness and Adjustable Optical Properties for Plasmon‐Based Applications (2020) (15)
- The genetics of primary open angle glaucoma (1997) (14)
- Alirocumab: First Global Approval (2015) (14)
- Enarodustat: First Approval (2020) (14)
- Detailed genetic mapping around a putative prostate-specific membrane antigen locus on human chromosome 11p11.2 (1998) (14)
- Male pseudohermaphroditism resulting from a novel mutation in the human steroid 5 alpha-reductase type 2 gene (SRD5A2). (1997) (14)
- Human menopausal and pregnant mare serum gonadotrophins in murine superovulation regimens for transgenic applications. (2007) (14)
- Evaluation of lipid-stabilised tripropionin nanodroplets as a delivery route for combretastatin A4. (2017) (14)
- The human gene encoding FKBP-rapamycin associated protein (FRAP) maps to chromosomal band 1p36.2 (1997) (14)
- A simple method for the preparation of 'ribonucleoside dialdehydes' and some comments on their structure. (1976) (14)
- Fostemsavir: First Approval (2020) (14)
- Characterisation of the alpha-1-antitrypsin M3 gene, a normal variant (1990) (14)
- Detection of ΔF508 deletion by amplification refractory mutation system (1990) (14)
- Margetuximab: First Approval (2021) (14)
- An EST and STS-based YAC contig map of human chromosome 9q22.3. (1996) (13)
- Envafolimab: First Approval (2022) (13)
- The effect of ketamine hydrochloride, a non-barbiturate parenteral anaesthetic on oxidative phosphorylation in rat liver mitochondria. (1981) (13)
- Human cDNA sequence homologous to the mouse LLRep3 gene family. (1990) (13)
- Characterisation of the human and mouse orthologues of the Drosophila ariadne gene (2000) (13)
- Erratum to: Roxithromycin: an update of its antimicrobial activity, pharmacokinetic properties and therapeutic use (1994) (13)
- Studies on transfer ribonucleic acids and related compounds. XXI. Synthesis and properties of guanine rich fragments from E. coli tRNAfMet 5'-end. (1978) (12)
- Felodipine/Metoprolol (2012) (12)
- DNA mismatch repair genes and their association with colorectal cancer (Review). (1998) (12)
- Brivaracetam: First Global Approval (2016) (12)
- Genetic analysis in cystic fibrosis using the amplification refractory mutation system (ARMS): the J3.11 MspI polymorphism. (1991) (12)
- Ponesimod: First Approval (2021) (12)
- Polymorphism at the tumour necrosis factor locus and asthma. (1996) (12)
- Pegvaliase: First Global Approval (2018) (11)
- Methotrexate: A Review of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Efficacy in Rheumatoid Arthritis and Other Immunoregulatory Disorders (1994) (11)
- Daridorexant: First Approval (2022) (10)
- Characterization of a human ubiquitin-conjugating enzyme gene UBE2L3 (1996) (10)
- Antagonists and the purinergic nerve hypothesis: 2, 2'-pyridylisatogen tosylate (PIT), an allosteric modulator of P2Y receptors. A retrospective on a quarter century of progress. (2000) (10)
- Effects of preincubation invitro with 3, 4-benzopyrene and phenobarbital on the drug-metabolism systems present in the microsomal and soluble fractions of the avocado pear (Persea americana). (1975) (10)
- Genomic organization of the human ubiquitin-conjugating enzyme gene, UBE2L6 on chromosome 11q12 (2000) (10)
- Fine mapping of the human 5-HTR2a gene to chromosome 13q14 and identification of two highly polymorphic linked markers suitable for association studies in psychiatric disorders. (1997) (10)
- Coeliac disease and Behçet’s disease (1997) (10)
- A carboxy terminal domain of the hMSH-2 gene product is sufficient for binding specific mismatched oligonucleotides. (1996) (10)
- Diltiazem. A review of its pharmacology and therapeutic use in older patients. (1993) (10)
- Screening for cancer predisposition. (1994) (10)
- Rapid determination of DNA concentration in multiple samples. (1989) (10)
- A comparison of the properties in vitro of biphenyl 2- and 4-hydroxylase in the mesocarp from avocado pear (Persea americana) and Syrian-hamster hepatic tissue. (1975) (9)
- CD105 is a prognostic marker and valid endothelial target for microbubble platforms in cholangiocarcinoma (2020) (9)
- Identification of multiple candidate genes for IBD susceptibility using high-density transcript mapping in the IBD2 locus on chromosome 12q. (1999) (9)
- Selenium homeostasis in the central nervous system of the rat. (1996) (9)
- RT-PCR investigation of fibronectin mRNA isoforms in malignant, normal and reactive oral mucosa. (1997) (9)
- Genomic analysis of human multigene families using chromosome-specific vectorette PCR. (1996) (9)
- High-frequency ultrasound for in vivo measurement of colon wall thickness in mice. (2012) (9)
- Mutation Detection by Clonal Sequencing of PCR Amplicons and Grouped Read Typing is Applicable to Clinical Diagnostics (2013) (9)
- Mapping the minimal domain of hMSH-2 sufficient for binding mismatched oligonucleotides. (1997) (9)
- Promoter analysis of the human ubiquitin-conjugating enzyme gene family UBE2L1-4, including UBE2L3 which encodes UbcH7. (2000) (9)
- Ofloxacin Otic Solution (2012) (9)
- Avatrombopag: A Review in Thrombocytopenia (2021) (9)
- Herpesvirus saimiri-mediated delivery of the adenomatous polyposis coli tumour suppressor gene reduces proliferation of colorectal cancer cells. (2011) (8)
- A human aldehyde dehydrogenase (aldose reductase) pseudogene: nucleotide sequence analysis and assignment to chromosome 3. (1992) (8)
- Role of spin trapping and P2Y receptor antagonism in the neuroprotective effects of 2,2'-pyridylisatogen tosylate and related compounds. (2002) (8)
- Two regions downstream of AATAAA in the human antithrombin III gene are important for cleavage-polyadenylation. (1987) (8)
- Identification of a new Leu354Pro mutation responsible for factor XIII deficiency (2001) (8)
- Inhaled Salmeterol/Fluticasone Propionate Combination (2000) (7)
- Gefapixant: First Approval (2022) (7)
- Developing Hollow-Channel Gold Nanoflowers as Trimodal Intracellular Nanoprobes (2018) (7)
- ΔF508 testing of the DNA bank of the Royal Manchester Children's Hospital (1990) (7)
- The isolation and characterisation of cDNA and genomic clones for human lecithin: cholesterol acyltransferase. (1987) (7)
- Assignment1 of herpesvirus-associated ubiquitin-specific protease gene HAUSP to human chromosome band 16p13.3 by in situ hybridization (1999) (7)
- Calcium antagonists and Bay K8644 promote depolarization of the rat heart mitochondrial membrane potential. Further evidence for a role in alteration of oxidative metabolism. (1993) (7)
- Erratum to Epoetin beta: a review of its pharmacological properties and clinical use in the management of anaemia associated with chronic renal failure (1996) (7)
- Erratum: Mutations in TSPAN12 Cause Autosomal-Dominant Familial Exudative Vitreoretinopathy (American Journal of Human Genetics (2010) 86 (248-253)) (2016) (7)
- Correction to: Camrelizumab: First Global Approval (2019) (7)
- Bay K 8644, modifier of calcium transport and energy metabolism in rat heart mitochondria: a new intracellular site of action (1990) (7)
- Characterization and Genomic Localization of a SMAD4 Processed Pseudogene. (2017) (7)
- Carcinoma of the lung: warts and all. (1996) (7)
- Identification of a Novel Microsatellite Marker Tightly Linked to the KAI–1 Gene for Predicting Prostate Cancer Progression (2000) (6)
- Neutrophil Gelatinase-associated Lipocalin as a Theragnostic Marker in Perihilar Cholangiocarcinoma (2018) (6)
- Yeast artificial chromosome cloning of the β-catenin locus on human chromosome 3p21–22 (1995) (6)
- The use of high-frequency ultrasound imaging and biofluorescence for in vivo evaluation of gene therapy vectors (2013) (6)
- Targeted microbubbles carrying lipid-oil-Nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, Combretastatin A4. (2021) (6)
- DominantMapper: Rule‐based analysis of SNP data for rapid mapping of dominant diseases in related nuclear families (2011) (6)
- cDNA cloning, genomic organization, and chromosomal localization of a novel human gene that encodes a kinesin-related protein highly similar to mouse Kif3C. (1998) (6)
- Illuminator, a desktop program for mutation detection using short-read clonal sequencing. (2011) (6)
- Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse development (2002) (6)
- Identification of a new Leu354Pro mutation responsible for factor XIII deficiency. (2001) (6)
- Synthesis of some 5'-amino-2',5'-dideoxy-5-iodouridine derivatives and their antiviral properties against herpes simplex virus. (1982) (6)
- Assignment1 of the ubiquitin conjugating enzyme gene, UBE2G2, to human chromosome band 21q22.3 by in situ hybridization (1999) (6)
- Rapid isolation of genomic clones for individual members of human multigene families: identification and localisation of UBE2L4, a novel member of a ubiquitin conjugating enzyme dispersed gene family. (1997) (6)
- DNA sequence analysis of the KM19 locus linked to cystic fibrosis (1990) (6)
- Developing gold nanotubes as photoacoustic contrast agents (2019) (6)
- Fine mapping of 12 previously unassigned EST clones to individual YACs in the familial Alzheimer’s disease (FAD) region of chromosome 14q24.3 (1998) (5)
- BDNF increases mitochondrial respiratory coupling, and glutamate metabolism, at complex I, but not complex II (2004) (5)
- Shadow autozygosity mapping by linkage exclusion (SAMPLE): a simple strategy to identify the genetic basis of lethal autosomal recessive disorders (2009) (5)
- Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells. (2020) (5)
- Identification of autosomal recessive disease loci using out‐bred nuclear families (2012) (5)
- STIMULATION OF SUBSTRATE OXIDATION IN RAT HEPATIC MITOCHONDRIA FOLLOWING PRETREATMENT WITH APPETITE MODIFYING DRUGS (1985) (5)
- Applications of oligonucleotide synthesis to interferon research. (1982) (5)
- Molecular genetics of the human glucokinase regulator-fructokinase (GCKR-KHK) region of chromosome 2p23. (1997) (5)
- Detection of delta F508 deletion by amplification refractory mutation system. (1990) (5)
- Identification and characterisation of a sequence related to human sorbitol dehydrogenase. (1997) (5)
- Perindopril 2mg/indapamide 0.625mg. Fixed low-dose combination. (1999) (5)
- Characterization of a brain-selective transcript of the Adenomatous polyposis coli tumor suppressor gene (2000) (5)
- Simple and Efficient Identification of Rare Recessive Pathologically Important Sequence Variants from Next Generation Exome Sequence Data (2013) (5)
- Increased Sensitivity of Diagnostic Mutation Detection by Re-analysis Incorporating Local Reassembly of Sequence Reads (2017) (4)
- Influence of terminal 3' phosphates or 2',3'-cyclic phosphates on the conformations of oligoriboadenylates, oligoribocytidylates, and the corresponding monomers. (1979) (4)
- Possible Applications of Recombinant DNA Technology to the Diagnosis and Study of Variants of α1-Antitrypsin (1985) (4)
- Uptake of 75-selenium into the central nervous system of the rat (2004) (4)
- A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on Chromosome 14q24.3 (1995) (4)
- Mutational analysis of the nucleotide binding domain of the mismatch repair enzyme hMSH-2. (1996) (4)
- Erratum to Mibefradil: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of hypertension and angina pectoris (1998) (4)
- Effect of the general anaesthetic propanidid on oxidative phosphorylation and calcium transport in rt liver mitochondria. (1981) (4)
- Inhaled Salmeterol/Fluticasone Propionate Combination (2000) (4)
- Structural and evolutionary characterization of the human sorbitol dehydrogenase gene duplication (1998) (4)
- Cytochrome P-450 in higher plants. (1976) (3)
- Detection of somatic mutations in tumors using unaligned clonal sequencing data (2014) (3)
- Ketotifen: A Review of its Therapeutic Efficacy in Dermatological Disorders (1996) (3)
- Rapid Visualisation of Microarray Copy Number Data for the Detection of Structural Variations Linked to a Disease Phenotype (2012) (3)
- Truncated adenomatous polyposis coli (APC) tumour suppressor protein can undergo tyrosine phosphorylation. (2000) (3)
- Haemochromatosis and type 2 diabetes (1998) (3)
- Activity of Novel Tryptophan Analogs against Mammalian and Trypanosomal Monoamine Oxidases (2005) (3)
- Freeze-Dried Therapeutic Microbubbles: Stability and Gas Exchange. (2020) (3)
- Characterization of human SHC p66 cDNA and its processed pseudogene mapping to Xq12-q13.1. (1997) (3)
- Theranostics: Engineering Gold Nanotubes with Controlled Length and Near‐Infrared Absorption for Theranostic Applications (Adv. Funct. Mater. 14/2015) (2015) (3)
- PAX 6, aniridia and Peters' anomaly (1997) (3)
- Characterization of the mouse ubiquitin-conjugating enzyme gene UbcM4 (1999) (3)
- Delta F508 testing of the DNA bank of the Royal Manchester Children's Hospital. (1990) (3)
- A new mutation in the human lipoprotein lipase gene causing familial hyperchylomicronaemia. (1997) (3)
- Yeast artificial chromosome cloning and chromosomal localization of the abundant odontogenic keratocyst protein elafin. (1996) (3)
- Fenoldopam (2018) (3)
- Autozygosity mapping of autosomal recessive non-syndromic sensorineural hearing loss (ARNSSNHL) (1994) (3)
- The use of synthetic oligonucleotides in the detection of the Z variant of α1-antitrypsin (α1-AT) (1984) (3)
- Correction to: Ibalizumab: First Global Approval (2018) (2)
- The synthesis of poly(acrylic acid hydrazide) and poly(methylacrylic acid hydrazide) and their reaction products with ribonucleoside dialdehydes (1976) (2)
- Clarithromycin and Omeprazole (2012) (2)
- The Role of Macrophage Migration Inhibitory Factor in Intestinal Tumorigenesis (2003) (2)
- An Approach to the Synthesis of Intermediate Sized Oligoribonucleitides (1977) (2)
- Zimberelimab: First Approval (2021) (2)
- Erratum to Danaparoid: a review of its pharmacology and clinical use in the management of heparin-induced thrombocytopenia (2012) (2)
- Oncogenes and Tumour Suppressor Genes in Prostate Cancer (2003) (2)
- Optimising gold nanorod size for maximum photoacoustic response while minimising cell toxicity (2017) (2)
- Transgenic models and cancer treatment. (1995) (2)
- Male pseudohermaphroditism resulting from a novel mutation in the human steroid 5 a-reductase type 2 gene ( SRD 5 A 2 ) (2)
- Long-Acting Isosorbide Mononitrate (2012) (2)
- Studies on transfer ribonucleic acids and related compounds. XXVII. Linear and cyclic oligonucleotides obtained by polymerization of protected ribonucleoside 3'-phosphates. (1979) (2)
- Corrigendum: Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy (2008) (2)
- Perindopril 2mg/Indapamide 0.625mg (1999) (2)
- Effect of calcium-modifying drugs on glutamate dehydrogenase and isocitrate dehydrogenase activity. (1990) (2)
- First Employment of British Pharmacology Graduates (2006) (2)
- (CGG) trinucleotide repeat polymorphism in the 5′ region of the HHR6B gene: the human homolog of the yeast DNA repair gene RAD6 (1995) (2)
- Flufenamic acid promotes the release of Ca2+ from isolated mitochondria (1985) (1)
- Mutations in TSPAN12 Cause Autosomal-Dominant Familial Exudative Vitreoretinopathy. (2016) (1)
- Dimethylsulfoxide for Renal Dysfunction Caused by Systemic Amyloidosis Complicating Crohn's Disease (1999) (1)
- Localisation of a cDNA clone for human cytokeratin 18 to chromosome 17p11–p12 by in situ hybridisation (1990) (1)
- Reduction in the resident intestinal myelomonocytic cell population occurs during ApcMin/+ mouse intestinal tumorigenesis (2021) (1)
- Non random usage of T cell receptor alpha gene expression in atopy using anchored PCR. (1996) (1)
- Physical mapping of the dominant optic atrophy gene, OPA1 (1997) (1)
- Novel primer specific false terminations during DNA sequencing reactions: danger of inaccuracy of mutation analysis in molecular diagnostics (1996) (1)
- Use of the polymerase chain reaction and direct sequencing for prenatal diagnosis of α1-antitrypsin deficiency (1989) (1)
- Two sequence-tagged sites defining the ends of a 380 kb YAC clone from 19q13. (1991) (1)
- Phyllis Jean McAlpine, Ph.D, FCCMG (1999) (1)
- Application of PCR to human gene detection. (1992) (1)
- Assignment1 of the murine adenomatous polyposis coli 2 (Apc2) gene to mouse chromosome band 10B5-C2 by in situ hybridisation (1999) (1)
- Roxithromycin (2012) (1)
- Isolation of a cdna clone corresponding to the MHC linked complement protein factor B (1982) (1)
- Assignment1 of UBE2D1 to human chromosome bands 10q11.2→q21 by in situ hybridization (1999) (1)
- Erratum to: Idelalisib: First Global Approval (2014) (1)
- Correction to: Avatrombopag: A Review in Thrombocytopenia (2021) (1)
- Lymphodepletion in the Apc Min/+ mouse model of intestinal tumorigenesis Short title:Lymphodepletion in the Apc Min/+ mouse (2013) (1)
- Correction to: Selpercatinib: First Approval (2020) (1)
- Erratum to: Pergolide: a review of its pharmacology and therapeutic use in Parkinson’s disease (1998) (1)
- Non Random Usage of T Cell Receptor α Gene Expression in Atopy Using Anchored PCR (1996) (1)
- intestinal tumorigenesis Short title: Stromal cell Cox-2 in intestinal tumorigenesis (2005) (1)
- Palmitoyl carnitine modifies energy and calcium metabolism associated with rat heart mitochondria (1987) (1)
- Correction to: Fostemsavir: First Approval (2020) (1)
- A plasmid cassette system that allows optimization of primers for use in the amplification refractory mutation system. (1991) (1)
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- Specific Activity Normal Polymorphisms Are Associated With High or Low Factor XIII Genotype/Phenotype Correlations for Coagulation Factor XIII: Specific (2010) (0)
- A Dominant Optic Atrophy Family with a Microdeletion at 3q28 Encompassing the OPA1 Gene: Evidence that Haploinsufficiency of OPA1 is the Cause of Disease (2002) (0)
- Yac clones comprising 55 mb of dna at the fap locus 5q21 in six contigs allow localisation of polymorphic markers and candidate tumour suppressor genes (1991) (0)
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- Prostate-specific membrane antigen genes lie within duplicated regions on human chromosome 11P11.2 and 11q14loci (1997) (0)
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- The Mapping of 3 Genetic Loci Involved in the Aetiology of Cerebral Palsy (1999) (0)
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- Assignment of GALGT encoding beta-1, 4N-acetylgalactosaminyl-transferase (GalNAc-T) and KIF5A encoding neuronal kinesin (D12S1889) to human chromosome band 12q13 by assignment to ICI YAC 26EG10 and in situ hybridization. medjph@stjames.leeds.ac.uk. (1998) (0)
- 2391 Evaluation of the endothelial marker CD105 as a prognostic biomarker and target for molecular theragnostics in perihilar cholangiocarcinoma (2015) (0)
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- ISOLATION OF YACS FOR CSF-1R AND CSF-1 AND GENE LOCALIZATION USING FISH (1992) (0)
- Cyclooxygenase-2 is localized to lamina propria cells in Min mouse intestine (1998) (0)
- Dofetilide (2012) (0)
- Evolutionary Changes in Microcephalin, a Protein Implicated in Determining Human Brain Size (2003) (0)
- Table of Contents (1986) (0)
- RETRACTED: Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse development (2002) (0)
- STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. XXI. SYNTHESIS AND PROPERTIES OF GUANINE-RICH FRAGMENTS FROM E. COLI TRNAFMET 5′-END (1979) (0)
- Loncastuximab tesirine in relapsed or refractory diffuse large B-cell lymphoma: a profile of its use in the USA (2022) (0)
- Therapeutic viral drug, which proceed the stops of tumors (1998) (0)
- viral therapeutic agent that stops the growth of tumors. (1998) (0)
- 45 Ca uptake into isolated tracheal cartilage from the guinea-pig: effect of temperature and Ca-modulating compounds (1989) (0)
- Abstract 1572: Characterising the tumor vasculaturein vivoin mouse models of colorectal cancer using contrast enhanced high-frequency ultrasound (2011) (0)
- hybridization probe and method for detecting the presence or absence of at least one sequence variant in one test (1989) (0)
- Erratum to: Reslizumab: First Global Approval (2016) (0)
- Trp156Ter mutation in the PAX6 gene in a family with aniridia (1998) (0)
- Irbesartan (2020) (0)
- ISOLATION OF NOVEL CDNA CLONES MAPPING TO THE CRITICAL REGION OF THE 5Q-CHROMOSOME IN THE 5Q-SYNDROME (1994) (0)
- AN APPROACH TO THE SYNTHESIS OF INTERMEDIATE-SIZED OLIGORIBONUCLEOTIDES (1978) (0)
- Synthesis of the nascent strand of tRNAfMet from E coli. (1979) (0)
- The effect of calcium ions on prostaglandin F2α, E2 and D2 biosynthesis in guinea-pig lung (1987) (0)
- Pegvaliase: First Global Approval (2018) (0)
- The mechanism of inhibition by 2,2'-pyridylisatogen tosylate of NADPH-linked enzyme activities in microsomes isolated from rat liver. (1985) (0)
- Determination of the extent of ischemic damage and the effect of the calcium antagonist, verapamil following coronary artery ligation in the rat. (1990) (0)
- A novel, rapid methodfortheisolation ofterminal sequencesfromyeastartificial chromosome (YAC)clones (1990) (0)
- Genomic Localization of a SMAD 4 Processed Pseudogene (2017) (0)
- A COMMON COAGULATION FACTOR 13A GENE VARIANT INFLUENCES OVERALL SURVIVAL OF OVARIAN CANCER PATIENTS (2004) (0)
- Telmisartan (2020) (0)
- Increased Sensitivity of Diagnostic Mutation Detection by Re-analysis Incorporating Local Reassembly of Sequence Reads (2017) (0)
- Sparfloxacin (2020) (0)
- Correction to: Oliceridine: First Approval (2020) (0)
- Factor XIIIA Gene, in a Factor XIII-Deficient Family Identification of a Large Deletion, Spanning Exons 4 to 11 of the Human (2010) (0)
- Chromosomal alterations associated with transformation of a tamoxifen-sensitive cell line into its drug resistant clone (2001) (0)
- Trefoil family factor 2(TFF2) results in disruption of intercellular junctions facilitating cell migration and restitution (2000) (0)
- Studies on transfer ribonucleic acids and related compounds. XXXIV. Stepwise diester or partial triester synthesis of penta- to octanucleotides corresponding to residues 41--46, 47--54, 61--65 and 66--71 of tRNAfMet of E. coli. (1980) (0)
- THE EFFECT OF CYPROHEPTADINE ON OXIDATIVE PHOSPHORYLATION IN RAT LIVER MITOCHONDRIA (1986) (0)
- Identification of Microdeletions at 1p36 by Fluorescence in Situ Hybridization in Cases of Malignant Lymphoma with Previously Normal Conventional Cytogenetic Findings (2003) (0)
- Molecular characterisation of two alpha-l-antitrypsin deficiency variants: proteinase inhibitor (Pi) NuliNew ort (GlyllS--- Ser) (1990) (0)
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