Alexander Rudensky

Alexander Rudensky's AcademicInfluence.com Rankings

Alexander Rudensky

Biology

#1635

World Rank

#2683

Historical Rank

#796

USA Rank

Immunology

#86

World Rank

#92

Historical Rank

#32

USA Rank

biology Degrees

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Biology

Why Is Alexander Rudensky Influential?

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According to Wikipedia, Alexander Rudensky is an immunologist at Memorial Sloan Kettering Cancer Center known for his research on regulatory T cells and the transcription factor Foxp3. Career Rudensky received his Candidate of Sciences degree in 1986 from the Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, and completed his postdoctoral work at the Yale School of Medicine. He is now the Chair of the Immunology Program and Director of the Ludwig Center at Memorial Sloan Kettering, as well as a professor at the Rockefeller University, Cornell University, Gerstner School of Graduate Studies, and Weill-Cornell Medical School.

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Alexander Rudensky's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells (2003) (7728)
Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation (2013) (2980)
Regulatory T cell lineage specification by the forkhead transcription factor foxp3. (2005) (2401)
Regulatory T cells: mechanisms of differentiation and function. (2012) (2371)
A function for interleukin 2 in Foxp3-expressing regulatory T cells (2005) (1892)
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice (2007) (1705)
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function (2008) (1518)
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. (2008) (1356)
A comparative encyclopedia of DNA elements in the mouse genome (2014) (1337)
Foxp3-dependent programme of regulatory T-cell differentiation (2007) (1146)
Sequence analysis of peptides bound to MHC class II molecules (1991) (1103)
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate (2010) (1064)
Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment (2018) (1054)
A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3 (2005) (1030)
TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells (2005) (994)
In Vivo Analysis of Dendritic Cell Development and Homeostasis (2009) (983)
CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner (2009) (954)
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation (2010) (944)
Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses (2010) (872)
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3 (2007) (866)
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells (2007) (863)
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. (2006) (808)
Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. (2009) (792)
Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. (2011) (791)
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. (2004) (773)
Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. (2003) (768)
Extrathymically generated regulatory T cells control mucosal TH2 inflammation (2012) (742)
Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo (2002) (741)
Foxp3 in control of the regulatory T cell lineage (2007) (715)
Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus. (1998) (704)
Regulatory T cells and Foxp3 (2011) (691)
Foxp 3 programs the development and function of CD 4 + CD 25 + regulatory T cells (2003) (673)
Stability of the Regulatory T Cell Lineage in Vivo (2010) (659)
A Distinct Function of Regulatory T Cells in Tissue Protection (2015) (654)
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires (2006) (601)
Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3− precursor cells in the absence of interleukin 10 (2007) (589)
Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs (2015) (587)
Control of regulatory T cell lineage commitment and maintenance. (2009) (579)
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses (2009) (574)
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells (2012) (563)
Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. (2011) (560)
Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice. (1997) (541)
Regulatory T cells: recommendations to simplify the nomenclature (2013) (536)
Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict (2012) (534)
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. (2006) (491)
Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway (2010) (474)
Developmental regulation of Foxp3 expression during ontogeny (2005) (463)
The plasticity and stability of regulatory T cells (2013) (459)
Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer. (2016) (438)
Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. (1999) (430)
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo (2009) (428)
Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification (2012) (424)
Lysosomal cysteine proteases regulate antigen presentation (2003) (423)
Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis (2007) (416)
Altering the distribution of Foxp3+ regulatory T cells results in tissue-specific inflammatory disease (2007) (413)
Dicer-dependent microRNA pathway safeguards regulatory T cell function (2008) (412)
An essential role for IL-2 receptor in regulatory T cell function (2016) (392)
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease (2008) (387)
Transcription factor Foxp3 and its protein partners form a complex regulatory network (2012) (373)
Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting. (2012) (330)
Regulation of immunity by self-reactive T cells (2005) (330)
T cell receptor signalling in the control of regulatory T cell differentiation and function (2016) (328)
The lysosomal cysteine proteases in MHC class II antigen presentation (2005) (317)
Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus (2014) (307)
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells (2001) (297)
On the complexity of self (1991) (293)
Hallmarks of Tissue-Resident Lymphocytes (2016) (275)
Intraclonal competition limits the fate determination of regulatory T cells in the thymus (2009) (274)
Continuous requirement for the T cell receptor for regulatory T cell function (2014) (273)
Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. (1997) (264)
Characterization of Mouse and Human B7-H3 Genes1 (2002) (257)
Novel Foxo1-dependent transcriptional programs control Treg cell function (2012) (255)
Stability and function of regulatory T cells expressing the transcription factor T-bet (2017) (253)
Immune homeostasis enforced by co-localized effector and regulatory T cells (2015) (248)
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity (2019) (247)
Differentiation of regulatory Foxp3+ T cells in the thymic cortex (2008) (243)
Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs (1992) (240)
Major Histocompatibility Complex Class II Compartments in Human and Mouse B Lymphoblasts Represent Conventional Endocytic Compartments (1997) (238)
Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy (2013) (234)
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution (2014) (230)
IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity (2010) (229)
Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation. (2011) (229)
Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. (2007) (227)
TGFβ signalling in control of T-cell-mediated self-reactivity (2007) (221)
Control of immune homeostasis by naturally arising regulatory CD4+ T cells. (2003) (213)
Tregs control the development of symptomatic West Nile virus infection in humans and mice. (2009) (211)
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells (2020) (208)
The role of the transcription factor Foxp3 in the development of regulatory T cells (2006) (206)
Cathepsin L Regulates CD4+ T Cell Selection Independently of Its Effect on Invariant Chain (2002) (205)
An essential role for the IL-2 receptor in Treg cell function (2016) (200)
Altered antigen presentation in mice lacking H2-O. (1998) (198)
The role of lysosomal proteinases in MHC class Il‐mediated antigen processing and presentation (1999) (196)
Importance of group X–secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model (2007) (195)
IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells (2013) (192)
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection (2014) (192)
A Role for Cathepsin L and Cathepsin S in Peptide Generation for MHC Class II Presentation1 (2002) (187)
Survival and Homeostatic Proliferation of Naive Peripheral CD4+ T Cells in the Absence of Self Peptide:MHC Complexes1 (2000) (182)
Cutting Edge: Depletion of Foxp3+ Cells Leads to Induction of Autoimmunity by Specific Ablation of Regulatory T Cells in Genetically Targeted Mice1 (2009) (181)
Thymic development and peripheral homeostasis of regulatory T cells. (2007) (181)
Regulatory T Cells: Differentiation and Function (2016) (177)
TGFbeta signalling in control of T-cell-mediated self-reactivity. (2007) (176)
Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity (2015) (174)
Control of inflammation by integration of environmental cues by regulatory T cells. (2013) (173)
The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells (2011) (170)
Interactions between innate and adaptive lymphocytes (2014) (168)
Cutting Edge: TCR Stimulation Is Sufficient for Induction of Foxp3 Expression in the Absence of DNA Methyltransferase 11 (2009) (166)
Regulation of thymic epithelium by keratinocyte growth factor. (2002) (166)
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses (2017) (162)
Dynamic Interactions of Macrophages with T Cells during Antigen Presentation (1999) (161)
In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses (2001) (153)
A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner. (2015) (142)
Monoclonal antibody detection of a major self peptide. MHC class II complex. (1992) (142)
Requirement for diverse, low-abundance peptides in positive selection of T cells. (1999) (140)
Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells (2014) (136)
Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells (2008) (134)
Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM). (2005) (128)
Antigen receptor repertoire profiling from RNA-seq data (2017) (128)
Intracellular assembly and transport of endogenous peptide-MHC class II complexes. (1994) (126)
Dynamic Tuning of T Cell Reactivity by Self-Peptide–Major Histocompatibility Complex Ligands (2001) (126)
Single-cell analysis of normal and FOXP 3-mutant human T cells : FOXP 3 expression without regulatory T cell development (2006) (125)
A mechanism for expansion of regulatory T cell repertoire and its role in self tolerance (2015) (125)
FOXP3 and NFAT: Partners in Tolerance (2006) (124)
Thymocyte expression of cathepsin L is essential for NKT cell development (2002) (123)
Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon (2014) (120)
In vivo sites and cellular mechanisms of T reg cell–mediated suppression (2006) (119)
Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity (2020) (116)
Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells (2009) (115)
Memory of Inflammation in Regulatory T Cells (2016) (115)
IL-2–dependent adaptive control of NK cell homeostasis (2013) (115)
Mouse TCRαβ+CD8αα Intraepithelial Lymphocytes Express Genes That Down-Regulate Their Antigen Reactivity and Suppress Immune Responses12 (2007) (115)
Differential Regulation of Cathepsin S and Cathepsin L in Interferon γ–treated Macrophages (2003) (113)
An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes. (2012) (113)
Cathepsin S Controls MHC Class II-Mediated Antigen Presentation by Epithelial Cells In Vivo1 (2005) (110)
miR-23∼27∼24 clusters control effector T cell differentiation and function (2016) (107)
Medullary Thymic Epithelium: A Mosaic of Epithelial “Self”? (1998) (107)
Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155 (2013) (106)
A critical role for regulatory T cell–mediated control of inflammation in the absence of commensal microbiota (2010) (105)
Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation. (2003) (103)
Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif. (2003) (99)
Bacterial metabolism of bile acids promotes peripheral Treg cell generation (2020) (97)
Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation1 (2005) (95)
Robust Antitumor Responses Result from Local Chemotherapy and CTLA-4 Blockade (2018) (94)
The effects of commensal microbiota on immune cell subsets and inflammatory responses (2012) (89)
The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types (2018) (88)
Molecular orchestration of differentiation and function of regulatory T cells. (2009) (83)
Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border‐Dwelling Bacteria and Affect Physiologic Metabolite Balance (2018) (82)
Lack of Foxp3 function and expression in the thymic epithelium (2007) (78)
Microbial metabolites control gut inflammatory responses (2014) (77)
Efficient Presentation of Both Cytosolic and Endogenous Transmembrane Protein Antigens on MHC Class II Is Dependent on Cytoplasmic Proteolysis1 (2001) (76)
Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses. (2007) (74)
The aryl hydrocarbon receptor controls cell-fate decisions in B cells (2017) (71)
A study of complexes of class II invariant chain peptide: Major histocompatibility complex class II molecules using a new complex‐specific monoclonal antibody (1996) (69)
ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity (2018) (69)
Molecular aspects of regulatory T cell development. (2004) (69)
Effects of the Administration of High-Dose Interleukin-2 on Immunoregulatory Cell Subsets in Patients with Advanced Melanoma and Renal Cell Cancer (2007) (67)
The Cell-Intrinsic Circadian Clock Is Dispensable for Lymphocyte Differentiation and Function. (2015) (66)
Invariant Chain–independent Function of H-2M in the Formation of Endogenous Peptide–Major Histocompatibility Complex Class II Complexes In Vivo (1998) (65)
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. (2020) (64)
Basophils Promote Tumor Rejection via Chemotaxis and Infiltration of CD8+ T Cells. (2017) (62)
Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse. (2010) (62)
Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides. (1998) (61)
Cathepsin S Regulates the Expression of Cathepsin L and the Turnover of γ-Interferon-inducible Lysosomal Thiol Reductase in B Lymphocytes* (2001) (59)
Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism. (2020) (58)
A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells (2019) (57)
Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function (2019) (56)
The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning1 (2002) (52)
Inflammation-induced repression of Foxp3-bound chromatin in regulatory T cells (2014) (52)
Requirement for peptide in alloreactive CD4+ T cell recognition of class II MHC molecules. (1995) (51)
Phenotype and function of CD4+ T cells in mice lacking invariant chain. (1996) (50)
Immunoglobulin‐specific T‐B cell interaction (1989) (47)
IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus (2019) (46)
Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b (2018) (46)
FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program (2019) (45)
Lysosomal cysteine proteases and antigen presentation. (2006) (44)
Regulatory T Cells in Cancer (2020) (43)
Competition for Specific Intrathymic Ligands Limits Positive Selection in a TCR Transgenic Model of CD4+ T Cell Development1 (2000) (43)
Immunoglobulin‐specific T‐B cell interaction (1989) (41)
Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells. (2019) (41)
Comparative analysis of murine T‐cell receptor repertoires (2018) (40)
Pillars Article: Foxp3 Programs the Development and Function of CD4+CD25+ Regulatory T Cells. Nat. Immunol. 2003. 4: 330-336. (2017) (40)
Runx-CBFβ complexes control Foxp3 expression in regulatory T cells (2009) (39)
Genetic and epigenetic variation in the lineage specification of regulatory T cells (2015) (39)
The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (Ctsl) gene (2001) (38)
Therapeutic use of regulatory T cells for graft‐versus‐host disease (2019) (38)
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers (2021) (38)
Trypanosoma cruzi‐infected macrophages are defective in major histocompatibility complex class II antigen presentation (1997) (38)
Variation in HLA-DM expression influences conversion of MHC class II alpha beta:class II-associated invariant chain peptide complexes to mature peptide-bound class II alpha beta dimers in a normal B cell line. (1996) (38)
Suppression of lethal autoimmunity by regulatory T cells with a single TCR specificity (2017) (36)
A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells (2021) (34)
Foxp3 and dominant tolerance (2005) (34)
Differential expression of CLIP: MHC class II and conventional endogenous peptide: MHC class II complexes by thymic epithelial cells and peripheral antigen‐presenting cells (1996) (34)
The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries. (2020) (33)
A nonimmune function of T cells in promoting lung tumor progression (2017) (31)
The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology. (2005) (30)
Effect of Decreasing the Affinity of the Class II-Associated Invariant Chain Peptide on the MHC Class II Peptide Repertoire in the Presence or Absence of H-2M1 (2004) (30)
Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells (2019) (30)
Mouse TCRαβ+CD8αα intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses (2007) (30)
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. (2021) (30)
A unified atlas of CD8 T cell dysfunctional states in cancer and infection. (2021) (28)
G Protein-Coupled Receptor 83 Is Dispensable for the Development and Function of Regulatory T Cells (2007) (27)
Inflammatory adaptation in barrier tissues (2021) (27)
Positive selection of self-MHC-reactive T cells by individual peptide–MHC class II complexes (2002) (26)
A unified atlas of CD8 T cell dysfunctional states in cancer and infection (2020) (26)
Cytotoxic granzyme C–expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity (2022) (26)
CD49b defines functionally mature Treg cells that survey skin and vascular tissues (2018) (26)
Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU) (2018) (25)
Presentation of endogenous immunoglobulin determinant to immunoglobulin‐recognizing T cell clones by the thymic cells (1990) (25)
Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. (1996) (25)
Treg Cells in Cancer: A Case of Multiple Personality Disorder (2012) (24)
Antigen‐specific dose‐dependent system for the study of an inheritable and reversible phenotype in mouse CD4+ T cells (2002) (23)
Transcriptional control of regulatory T-cell differentiation. (2013) (23)
Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota (2022) (22)
Assembly of an abundant endogenous major histocompatibility complex class II/peptide complex in class II compartments (1997) (22)
Regulatory T Cells Function in Established Systemic Inflammation and Reverse Fatal Autoimmunity (2021) (22)
Presentation of abundant endogenous class II DR‐restricted antigens by DM‐negative B cell lines (1997) (21)
Regulatory T cells expressing interleukin 10 develop from Foxp3 + and Foxp3 - precursor cells in the absence (2007) (20)
Evaluating peptide repertoires within the context of thymocyte development. (1999) (19)
Single-Cell Immune Map of Breast Carcinoma Reveals Diverse Phenotypic States Driven by the Tumor Microenvironment (2017) (18)
An altered invariant chain protein with an antigenic peptide in place of CLIP forms SDS-stable complexes with class II alphabeta dimers and facilitates highly efficient peptide loading. (1998) (18)
Immunoglobulin‐specific T‐B cell interaction. IV. B cell presentation of idiotypic determinant(s) of monoclonal anti‐surface immunoglobulin antibody to idiotope‐recognizing helper T clones (1990) (17)
T and B cell receptors discriminate major histocompatibility complex class II conformations influenced by the invariant chain (1992) (17)
Assembly of a spatial circuit of T-bet–expressing T and B lymphocytes is required for antiviral humoral immunity (2021) (17)
Studies on naturally processed peptides associated with MHC class II molecules. (1993) (17)
Immunoglobulin-specific T-B cell interaction. I. Presentation of self immunoglobulin determinants by B lymphocytes. (1989) (16)
Dual TCR T cells: gaining entry into the periphery (2002) (16)
T reg cell–intrinsic requirements for ST2 signaling in health and neuroinflammation (2020) (15)
Mtv-1 Superantigen Trafficks Independently of Major Histocompatibility Complex Class II Directly to the B-Cell Surface by the Exocytic Pathway (1998) (14)
Foxp3: a genetic foundation for regulatory T cell differentiation and function (2020) (14)
Recognition of the Peripheral Self by Naturally (2004) (14)
Regulatory T Cell Ablation Causes Acute T Cell Lymphopenia (2014) (14)
Immunoglobulin‐specific T‐B cell interaction III. B cell activation by immunoglobulinrecognizing T cell clones (1990) (14)
Single-cell Map of Diverse Immune Phenotypes Driven by the Tumor Microenvironment (2018) (13)
Endogenous peptides associated with MHC class II and selection of CD4 T cells. (1995) (13)
The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (CtsI) gene. (2001) (13)
Nuclear receptor LXRβ controls fitness and functionality of activated T cells (2020) (13)
Intraclonal competition limits regulatory T cell fate determination in the thymus (2009) (13)
FXR mediates T cell-intrinsic responses to reduced feeding during infection (2020) (11)
Author Correction: An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses (2018) (11)
Gasdermin D–mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma (2022) (11)
T Cell Receptor Signaling in the Control of Regulatory T Cell Differentiation and Function (2016) (10)
Hierarchical Regulation of the Resting and Activated T Cell Epigenome by Major Transcription Factor Families (2021) (9)
Erratum: A function for interleukin 2 in Foxp3-expressing regulatory T cells (2006) (9)
Current opportunities to catalyze research in nutrition and cancer prevention – an interdisciplinary perspective (2019) (9)
Distinct Requirements of CHD4 during B Cell Development and Antibody Response (2019) (9)
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease (2008) (9)
Regulatory CD4 T cells (2006) (8)
A narrow circle of mutual friends. (2011) (8)
Antigen processing and recognition: Recent developments (2004) (8)
SUPPLEMENTAL EXPERIMENTAL PROCEDURES (2012) (8)
ZFP36 RNA-binding proteins restrain T-cell activation and anti-viral immunity (2018) (7)
The Piv-Otal Class II Transactivator Promoter Regulates Major Histocompatibility Complex Class II Expression in the Thymus (2001) (7)
DNA methylation secures CD4+ and CD8+ T cell lineage borders (2015) (7)
Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells. (2022) (7)
Principles of regulatory T cell function. (2023) (6)
Peptide loading in the endoplasmic reticulum accelerates trafficking of peptide:MHC class II complexes in B cells. (1999) (5)
The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis. (2022) (5)
Microcolumn Liquid Chromatography—Electrospray Ionization Tandem Mass Spectrometry: Analysis of Immunological Samples (1996) (4)
Phase I/II study of mogamulizumab, an anti-CCR4 antibody targeting regulatory T cells in advanced cancer patients. (2016) (4)
Mouse Watch: A Cautionary Tale. (2019) (4)
BRCT-domain protein BRIT1 influences class switch recombination (2017) (4)
Conceiving the Inconceivable: The Function of Aire in Immune Tolerance to Peripheral Tissue-Restricted Antigens in the Thymus (2021) (4)
Corrigendum: Stability and function of regulatory T cells expressing the transcription factor T-bet (2017) (4)
Differential Regulation of Cathepsin S and Cathepsin L in Interferon (cid:2) –treated Macrophages (2003) (3)
CXCR4+ Treg cells control serum IgM levels and natural IgM autoantibody production by B-1 cells in the bone marrow (2021) (3)
Author response: Genetic and epigenetic variation in the lineage specification of regulatory T cells (2015) (2)
Author response: ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity (2018) (2)
Skin stem cells orchestrate de novo generation of extrathymic regulatory T cells to establish a temporary protective niche during wound healing (2021) (2)
Leading Edge Minireview FOXP 3 and NFAT : Partners in Tolerance (2006) (2)
Heterogeneity of Inflammation-associated Synovial Fibroblasts in Rheumatoid Arthritis and Its Drivers (2022) (2)
Starfysh reveals heterogeneous spatial dynamics in the breast tumor microenvironment (2022) (1)
A novel lineage of ROR g t + Aire + antigen presenting cells promotes peripheral generation of intestinal regulatory T cells and tolerance during early life (2022) (1)
Immigration in science (2020) (1)
A Single miRNA-mRNA Int eraction Affects the Immune Response in a Context-and Cell-Type-Specific Manner Highlights (2015) (1)
Peptides bound to MHC (1992) (1)
Reigning in regulatory T-cell function (2015) (1)
Visualizing Allogeneic Bone Marrow (BM) Graft Rejection. (2004) (1)
Effects of theAdministration of High-Dose Interleukin-2 on Immunoregulatory Cell Subsets in Patients with AdvancedMelanoma and Renal Cell Cancer (2007) (1)
Immunotherapy breaches low-sugar dieting of tumor Treg cells. (2021) (1)
Terminal differentiation and persistence of effector regulatory T cells essential for the prevention of intestinal inflammation (2022) (1)
Peptide Loading in the Endoplasmic Reticulum Accelerates Trafficking of Peptide:MHC Class II Complexes in B Cells (1999) (1)
Abstract P4-04-11: Preferential expression of the chemokine receptor 8 (CCR8) on regulatory T cells (Treg) infiltrating human breast cancers represents a novel immunotherapeutic target (2016) (1)
The ICOS:ICOSL Costimulatory Pathway Plays an Important Role in GVHD and Bone Marrow (BM) Graft Rejection. (2004) (1)
Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families (2021) (0)
Immune tolerance : a subject collection from Cold Spring Harbor perspectives in biology (2013) (0)
Context specific regulation of microRNA targets in the immune system (P1142) (2013) (0)
a Stat 3-Dependent Manner 17 Responses inH Regulatory T Cells Control T + CD 4 (2010) (0)
Presence or Absence of H-2 M 1 MHC Class II Peptide Repertoire in the II-Associated Invariant Chain Peptide on the Effect of Decreasing the Affinity of the Class (2004) (0)
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells (2020) (0)
FoxP3 can fold into two distinct dimerization states with divergent functional implications for T cell homeostasis (2022) (0)
Abstract B081: Tissue repair function of regulatory T cells during infection and cancer progression (2016) (0)
Regulatory T cells in infection and autoimmunity (2009) (0)
A novel RORγt+ antigen presenting cell type instructs microbiota-dependent regulatory T cell differentiation and tolerance during early life (2022) (0)
Abstract A062: The effects of cellular context on miR-155 mediated regulation of gene expression (2016) (0)
Spatiotemporal regulation of peripheral T cell tolerance (2023) (0)
Tolerance : The Interplay of Clonal Anergy Mechanisms of Anti-CD 154-Induced Graft Analysis of the Underlying Cellular (2005) (0)
Su.135. Regulatory T-Cell Expression of CCR4 is Required to Prevent Cutaneous & Pulmonary Inflammation (2006) (0)
Regulatory T Cell Function in Established Systemic Autoimmune Inflammation: Reversal and Containment of a Fatal Disease (2021) (0)
CXCR4+ Treg cells control serum IgM levels and natural IgM autoantibody production by B-1 cells in the bone marrow (2022) (0)
The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types (2018) (0)
A microbiota-derived metabolite instructs peripheral efferocytosis (2022) (0)
Host Conditioning Graft-Versus-Host Disease Is Determined by and Suppression Versus Lethal The Balance Between Donor T Cell Anergy (2002) (0)
Foxp3: a genetic foundation for regulatory T cell differentiation and function (2020) (0)
and Function of Regulatory T Cells Dispensable for the Development and G Protein-Coupled Receptor 83 Is (2007) (0)
The role of IRF4 in regulating effector CD8+ T cell development via repression of EOMES expression. (111.51) (2012) (0)
T reg Cells A Case (2016) (0)
Scope and mechanisms of peripherally generated regulatory T cell mediated suppression in inflammatory contexts (P1031) (2013) (0)
Editorial overview: The value of commitment in the lymphocyte world. (2019) (0)
Peptide Generation for MHC Class II A Role for Cathepsin L and Cathepsin S in Beers and (2002) (0)
Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity (2021) (0)
ANTIGEN PROCESSING AND PRESENTATION BY MHC CLASS I AND MHC CLASS II MOLECULES (1998) (0)
Th17 / Treg (SY2-1) Chairpersons: Shimon Sakaguchi, Daniel Cua (2010) (0)
Faculty Opinions recommendation of CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. (2002) (0)
Enforcing T cell innocence (2020) (0)
Automated high through put analysis of peptides associated with MHC class II molecules (1997) (0)
Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology. (2023) (0)
Author Correction: An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses (2018) (0)
Abstract A072: Glucose metabolism and O-linked GlcNAcylation in the tissue repair function of Treg cells (2016) (0)
Intracellular Trafficking of MHC Class II Molecules (1996) (0)
B 7-H 3 Genes Characterization of Mouse and Human (2002) (0)
Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies. (2023) (0)
Pillars Article: Sequence Analysis of Peptides Bound to MHC Class II Molecules. Nature. 1991. 353: 622-627. (2016) (0)
Cytoplasmic Proteolysis Antigens on MHC Class II Is Dependent on Endogenous Transmembrane Protein Efficient Presentation of Both Cytosolic and (2001) (0)
Early Immune Infiltrate and Tumor-Specific Immune Response Resulting in Improved Survival with Combination of Local Chemotherapy and Immune Checkpoint Blockade (2015) (0)
Editorial overview: lymphocyte development. (2009) (0)
Rules for the Presentation of Peptides by Class II Molecules of the Major Histocompatibility Complex (1993) (0)
Role of self peptides in T-cell development in the thymus (1999) (0)
B lymphocytes as natural antigen-presenting cells (APC) of their own Ig receptor determinants (1986) (0)
Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b (2018) (0)
G Protein-Coupled Receptor 83 Is Dispensable for the Development and Function of Regulatory T Cells (cid:1) (2007) (0)
Down-Regulate Their Antigen Reactivity and Lymphocytes Express Genes That Intraepithelial αα CD 8 + βα Mouse TCR (2007) (0)
Abstract A190: Mechanisms governing Foxp3-dependent and -independent gene expression in regulatory T-cells in evolutionary distant mice (2019) (0)
Epithelial Cells In Vivo II-Mediated Antigen Presentation by Cathepsin S Controls MHC Class (2005) (0)
A mechanism involving sibling transcription factor assistance preserves the integrity of an active Foxp3 locus in peripherally induced regulatory T cells. (2018) (0)
Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function (2019) (0)
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses (2017) (0)
Improving the Technology of Road Asphalt Concrete Mixes Manufacturing by Using Pre-Prepared Granules of Asphalt Binder Concentrate (2015) (0)
Rational Application of Building Materials and Resource Saving — Actual Way of Improving Works Efficiency When Constructing and Repairing Automobile Roads (2017) (0)

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