Alexander Van Oudenaarden
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Alexander Van Oudenaarden's AcademicInfluence.com Rankings
Alexander Van Oudenaardenphysics Degrees
Physics
#6584
World Rank
#8548
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Biophysics
#269
World Rank
#280
Historical Rank
Alexander Van Oudenaardenbiology Degrees
Biology
#11073
World Rank
#14448
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Systems Biology
#29
World Rank
#29
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Molecular Biology
#1666
World Rank
#1694
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Physics Biology
Alexander Van Oudenaarden's Degrees
- PhD Physics Leiden University
- Masters Physics Leiden University
Why Is Alexander Van Oudenaarden Influential?
(Suggest an Edit or Addition)Alexander Van Oudenaarden's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression (2009) (2770)
- Imaging individual mRNA molecules using multiple singly labeled probes (2008) (1560)
- Intrinsic noise in gene regulatory networks (2001) (1434)
- Population genomics of domestic and wild yeasts (2008) (1405)
- The Human Cell Atlas (2017) (1285)
- Direct cell reprogramming is a stochastic process amenable to acceleration (2009) (1020)
- Noise Propagation in Gene Networks (2005) (814)
- A Single-Cell Transcriptome Atlas of the Human Pancreas (2016) (786)
- MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. (2007) (743)
- The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers (2012) (704)
- Using Gene Expression Noise to Understand Gene Regulation (2012) (677)
- Variability in gene expression underlies incomplete penetrance (2009) (653)
- MicroRNAs can generate thresholds in target gene expression (2011) (625)
- Snowdrift game dynamics and facultative cheating in yeast (2009) (606)
- Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations (2017) (605)
- Stochastic Gene Expression in Fluctuating Environments (2004) (553)
- Long‐term expanding human airway organoids for disease modeling (2019) (488)
- De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data (2016) (429)
- Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters. (2016) (423)
- Integrated genome and transcriptome sequencing from the same cell (2014) (402)
- An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity (2019) (377)
- Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins (2013) (356)
- The Frequency Dependence of Osmo-Adaptation in Saccharomyces cerevisiae (2008) (354)
- Single-molecule approaches to stochastic gene expression. (2009) (346)
- MicroRNA control of protein expression noise (2015) (327)
- Motility of ActA protein-coated microspheres driven by actin polymerization. (1999) (295)
- RNA sequencing reveals two major classes of gene expression levels in metazoan cells (2011) (288)
- Identifying the stem cell of the intestinal crypt: strategies and pitfalls. (2012) (278)
- Single-Cell Transcriptomics Meets Lineage Tracing. (2018) (262)
- Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity (2016) (256)
- Systematic Identification of Signal-Activated Stochastic Gene Regulation (2013) (251)
- Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. (2014) (243)
- A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal (2012) (238)
- Attenuation of noise in ultrasensitive signaling cascades. (2002) (233)
- Characterization of directed differentiation by high-throughput single-cell RNA-Seq (2014) (227)
- Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells. (2017) (222)
- Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures. (2010) (221)
- Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon (2016) (216)
- Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts. (2015) (214)
- An in vitro model of early anteroposterior organization during human development (2020) (207)
- Brownian ratchets: molecular separations in lipid bilayers supported on patterned arrays. (1999) (201)
- Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids (2020) (192)
- Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation (2018) (186)
- Stochastic gene expression: from single molecules to the proteome. (2007) (183)
- Predicting stochastic gene expression dynamics in single cells. (2006) (180)
- Probing polymerization forces by using actin-propelled lipid vesicles (2003) (180)
- Genetic and phenotypic diversity in breast tumor metastases. (2014) (175)
- Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy. (2019) (173)
- A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche. (2017) (170)
- Quantitative time-lapse fluorescence microscopy in single cells. (2009) (163)
- Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. (2014) (161)
- Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. (2012) (161)
- Differential Stoichiometry among Core Ribosomal Proteins (2014) (159)
- A physical sciences network characterization of non-tumorigenic and metastatic cells (2013) (157)
- Circadian Gating of the Cell Cycle Revealed in Single Cyanobacterial Cells (2010) (156)
- A system of counteracting feedback loops regulates Cdc42p activity during spontaneous cell polarization. (2005) (151)
- Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells (2016) (149)
- Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. (2016) (138)
- Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. (2019) (137)
- A Novel Sperm-Delivered Toxin Causes Late-Stage Embryo Lethality and Transmission Ratio Distortion in C. elegans (2011) (136)
- Motility of Escherichia coli cells in clusters formed by chemotactic aggregation (2003) (134)
- Heritable Stochastic Switching Revealed by Single-Cell Genealogy (2007) (123)
- Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids (2019) (123)
- Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart (2019) (120)
- Single-cell analysis reveals that noncoding RNAs contribute to clonal heterogeneity by modulating transcription factor recruitment. (2012) (118)
- Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy (2018) (111)
- Mapping the physical network of cellular interactions (2018) (101)
- Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential (2018) (98)
- Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein (2011) (98)
- Single molecule fluorescent in situ hybridization (smFISH) of C. elegans worms and embryos. (2012) (98)
- Dampening of expression oscillations by synchronous regulation of a microRNA and its target (2013) (96)
- A General Mechanism for Network-Dosage Compensation in Gene Circuits (2010) (95)
- Unravelling cellular relationships during development and regeneration using genetic lineage tracing (2019) (92)
- Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells (2018) (91)
- Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta (2018) (90)
- Growth Landscape Formed by Perception and Import of Glucose in Yeast (2009) (90)
- Constant growth rate can be supported by decreasing energy flux and increasing aerobic glycolysis. (2014) (88)
- Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche. (2016) (88)
- LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (87)
- Repetitive sequence variation and dynamics in the ribosomal DNA array of Saccharomyces cerevisiae as revealed by whole-genome resequencing. (2009) (84)
- Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2 (2014) (82)
- Cellular asymmetry and individuality in directional sensing. (2006) (79)
- A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary (2015) (78)
- Allele-specific detection of single mRNA molecules in situ (2013) (74)
- Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic Injury (2017) (72)
- Robustness and epistasis in the C. elegans vulval signaling network revealed by pathway dosage modulation. (2013) (71)
- Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer. (2011) (63)
- Transcript counting in single cells reveals dynamics of rDNA transcription (2010) (62)
- Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies (2020) (59)
- Neuromesodermal progenitors are a conserved source of spinal cord with divergent growth dynamics (2018) (56)
- Stochastic Cytokine Expression Induces Mixed T Helper Cell States (2013) (56)
- Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells (2018) (56)
- Identification of molecular compartments and genetic circuitry in the developing mammalian kidney (2012) (55)
- Tdrd6a Regulates the Aggregation of Buc into Functional Subcellular Compartments that Drive Germ Cell Specification (2018) (53)
- Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling (2015) (51)
- Circadian networks in human embryonic stem cell‐derived cardiomyocytes (2017) (50)
- The Caenorhabditis elegans Synthetic Multivulva Genes Prevent Ras Pathway Activation by Tightly Repressing Global Ectopic Expression of lin-3 EGF (2011) (50)
- Caenorhabditis elegans aristaless/Arx gene alr-1 restricts variable gene expression (2011) (50)
- Power-limited contraction dynamics of Vorticella convallaria: an ultrafast biological spring. (2008) (48)
- A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes (2012) (45)
- Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells (2018) (44)
- Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion (2019) (44)
- Cell Type Purification by Single-Cell Transcriptome-Trained Sorting (2018) (43)
- Massively parallel clonal analysis using CRISPR/Cas9 induced genetic scars (2016) (43)
- FuseFISH: robust detection of transcribed gene fusions in single cells. (2013) (41)
- Spatial Transcriptomics of C. elegans Males and Hermaphrodites Identifies Sex-Specific Differences in Gene Expression Patterns. (2018) (38)
- Studying lineage decision-making in vitro: emerging concepts and novel tools. (2015) (37)
- Cell intrinsic modulation of Wnt signaling controls neuroblast migration in C. elegans. (2014) (37)
- Single-cell Ribo-seq reveals cell cycle-dependent translational pausing (2021) (36)
- 3D gastruloids: a novel frontier in stem cell-based in vitro modeling of mammalian gastrulation. (2021) (35)
- Necessary Noise (2007) (34)
- The thrombospondin repeat containing protein MIG-21 controls a left-right asymmetric Wnt signaling response in migrating C. elegans neuroblasts. (2012) (32)
- Tomo-seq: A method to obtain genome-wide expression data with spatial resolution. (2016) (32)
- Elastic instability in growing yeast colonies. (2004) (31)
- The Majority of CD45– Ter119– CD31– Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors (2018) (29)
- High-throughput total RNA sequencing in single cells using VASA-seq (2022) (29)
- A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. (2014) (28)
- Imaging single mRNA molecules in yeast. (2010) (27)
- Embryonic signals perpetuate polar-like trophoblast stem cells and pattern the blastocyst axis (2019) (23)
- H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity (2021) (21)
- Transcriptionally Profiling Cells Sorted by Transcript Abundance (2014) (19)
- Spindle checkpoint silencing at kinetochores with submaximal microtubule occupancy (2018) (18)
- Coupling cellular oscillators--circadian and cell division cycles in cyanobacteria. (2010) (17)
- UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit (2012) (17)
- Long-term expanding human airway organoids for disease modelling (2018) (17)
- BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states. (2022) (17)
- Single-cell transcriptomics enters the age of mass production. (2015) (17)
- Publisher Correction: Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids (2020) (16)
- Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies. (2016) (15)
- A Caenorhabditis elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility (2018) (15)
- Inter- and intratumoral heterogeneity of BCL2 correlates with IgH expression and prognosis in follicular lymphoma (2014) (14)
- Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression (2015) (13)
- A transcriptomic roadmap to α- and β-cell differentiation in the embryonic pancreas (2019) (11)
- Sharq, A versatile preprocessing and QC pipeline for Single Cell RNA-seq (2018) (10)
- Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development (2019) (10)
- Patched Receptors Sense, Interpret, and Establish an Epidermal Hedgehog Signaling Gradient. (2017) (10)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (7)
- Molecular characterization of Barrett’s esophagus at single-cell resolution (2021) (7)
- An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity (2019) (7)
- Integration of multiple lineage measurements from the same cell reconstructs parallel tumor evolution (2022) (6)
- Hierarchical chromatin regulation during blood formation uncovered by single-cell sortChIC (2021) (6)
- Correction: Neuromesodermal progenitors are a conserved source of spinal cord with divergent growth dynamics (doi: 10.1242/dev.166728) (2019) (6)
- When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes. (2012) (6)
- Droplet-based Single-cell Total RNA-seq Reveals Differential Non-Coding Expression and Splicing Patterns during Mouse Development (2021) (5)
- Deconvolving the roles of Wnt ligands and receptors in sensing and amplification (2013) (5)
- Exciting fluctuations: monitoring competence induction dynamics at the single-cell level (2006) (5)
- A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart (2018) (4)
- Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero. (2022) (4)
- An in vitro model of early anteroposterior organization during human development (2020) (4)
- Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo (2021) (3)
- Microbiology. Necessary noise. (2007) (3)
- Author response: Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart (2019) (3)
- Deconvolving multiplexed histone modifications in single cells (2021) (3)
- Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis (2022) (3)
- Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments (2021) (2)
- Correction: Neuromesodermal progenitors are a conserved source of spinal cord with divergent growth dynamics (2020) (2)
- Single-Cell Transcriptomics Links Loss of Human Pancreatic β-Cell Identity to ER Stress (2021) (2)
- Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy (2022) (2)
- Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids (2020) (2)
- LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (1)
- LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (1)
- Correction: Spindle checkpoint silencing at kinetochores with submaximal microtubule occupancy (doi:10.1242/jcs.231589) (2019) (1)
- Spatial transcriptomics of C. elegans males and hermaphrodites identifies novel fertility genes (2018) (1)
- scChIX-seq infers dynamic relationships between histone modifications in single cells. (2023) (1)
- Transcription factor induction of vascular blood stem cell niches in vivo (2021) (1)
- Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells (2018) (0)
- Paradoxical activation of oncogenic signaling as a cancer treatment strategy (2023) (0)
- Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells (2019) (0)
- Celebrating 100 years of Developmental Biology at the Hubrecht Institute. (2017) (0)
- Publisher Correction: Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids (2020) (0)
- Acceleration of genome replication uncovered by single-cell nascent DNA sequencing (2022) (0)
- Unravelling cellular relationships during development and regeneration using genetic lineage tracing (2019) (0)
- Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta (2018) (0)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (0)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (0)
- Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids (2019) (0)
- Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells (2017) (0)
- Functional modules from variable genes: Leveraging percolation to analyze noisy, high-dimensional data (2020) (0)
- Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells (2018) (0)
- Mapping the physical network of cellular interactions (2018) (0)
- How to regulate a gene: to repress or to activate? (2012) (0)
- Dynamics of Meiotic Sex Chromosome Inactivation and Pachytene Activation in Mice Spermatogenesis (2019) (0)
- Blastocyst-like structures generated solely from stem cells (2018) (0)
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