Alexandre Prat
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Computer Science
Alexandre Prat's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Alexandre Prat's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation (2007) (1524)
- The blood-brain barrier. (2015) (1307)
- Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and CNS inflammation via the aryl hydrocarbon receptor (2016) (652)
- The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence (2011) (627)
- Preferential recruitment of interferon‐γ–expressing TH17 cells in multiple sclerosis (2009) (500)
- Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system (2008) (403)
- Glial influence on the Blood Brain Barrier (2013) (395)
- Brain‐immune connection: Immuno‐regulatory properties of CNS‐resident cells (2000) (381)
- An updated histological classification system for multiple sclerosis lesions (2016) (352)
- Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation (2014) (336)
- Glial cell influence on the human blood‐brain barrier (2001) (325)
- How do immune cells overcome the blood–brain barrier in multiple sclerosis? (2011) (318)
- Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy (2015) (315)
- Disruption of central nervous system barriers in multiple sclerosis. (2011) (268)
- Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis (2019) (263)
- Defining secondary progressive multiple sclerosis. (2016) (247)
- Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier (2013) (235)
- Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 (2019) (234)
- How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging? (2013) (231)
- Angiotensin II Controls Occludin Function and Is Required for Blood–Brain Barrier Maintenance: Relevance to Multiple Sclerosis (2007) (219)
- Functional Consequences of Neuromyelitis Optica-IgG Astrocyte Interactions on Blood-Brain Barrier Permeability and Granulocyte Recruitment1 (2008) (215)
- Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 (2019) (208)
- Treatment Optimization in MS: Canadian MS Working Group Updated Recommendations (2013) (199)
- MAFG-driven astrocytes promote CNS inflammation (2020) (199)
- Determinants of Human B Cell Migration Across Brain Endothelial Cells1 (2003) (192)
- The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells. (2008) (174)
- Neutrophils Mediate Blood–Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases (2014) (165)
- Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way (2012) (159)
- Retinoic Acid Induces Blood–Brain Barrier Development (2013) (159)
- Statins reduce human blood–brain barrier permeability and restrict leukocyte migration: Relevance to multiple sclerosis (2006) (158)
- Predictors of long‐term disability accrual in relapse‐onset multiple sclerosis (2016) (145)
- Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation. (2015) (143)
- Defining reliable disability outcomes in multiple sclerosis. (2015) (140)
- Netrin 1 regulates blood-brain barrier function and neuroinflammation. (2015) (136)
- Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study (2017) (134)
- Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation (2013) (130)
- Migration of multiple sclerosis lymphocytes through brain endothelium. (2002) (127)
- MicroRNAs Regulate Human Brain Endothelial Cell-Barrier Function in Inflammation: Implications for Multiple Sclerosis (2013) (125)
- Role of ninjurin‐1 in the migration of myeloid cells to central nervous system inflammatory lesions (2011) (122)
- Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system (2009) (121)
- Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system. (2012) (120)
- Interpericyte tunnelling nanotubes regulate neurovascular coupling (2020) (118)
- Glial influences on BBB functions and molecular players in immune cell trafficking. (2016) (118)
- Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study (2020) (117)
- Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS (2012) (115)
- B Cells in the Multiple Sclerosis Central Nervous System: Trafficking and Contribution to CNS-Compartmentalized Inflammation (2015) (115)
- Myeloid cell transmigration across the CNS vasculature triggers IL-1β–driven neuroinflammation during autoimmune encephalomyelitis in mice (2016) (112)
- Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation (2019) (108)
- Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis (2012) (108)
- Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes (2021) (108)
- Caspase-3 Activation Triggers Extracellular Cathepsin L Release and Endorepellin Proteolysis* (2008) (108)
- Focal disturbances in the blood–brain barrier are associated with formation of neuroinflammatory lesions (2015) (101)
- Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on α4 integrin (2011) (100)
- NKG2D-Mediated Cytotoxicity toward Oligodendrocytes Suggests a Mechanism for Tissue Injury in Multiple Sclerosis (2007) (97)
- TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types (2018) (94)
- Therapeutic decisions in multiple sclerosis: moving beyond efficacy. (2013) (93)
- Barcoded viral tracing of single-cell interactions in central nervous system inflammation (2021) (92)
- Regulation of Th1 and Th2 Lymphocyte Migration by Human Adult Brain Endothelial Cells (2001) (90)
- Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis (2016) (89)
- Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS (2019) (89)
- Interferon‐γ secretion by peripheral blood T‐cell subsets in multiple sclerosis: Correlation with disease phase and interferon‐β therapy (1999) (89)
- Towards personalized therapy for multiple sclerosis: prediction of individual treatment response (2017) (85)
- Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology? (2016) (85)
- Interferon beta promotes nerve growth factor secretion early in the course of multiple sclerosis. (2005) (83)
- Regulation and Functional Effects of Monocyte Migration across Human Brain‐Derived Endothelial Cells (2003) (83)
- Kinin B1 Receptor Expression and Function on Human Brain Endothelial Cells (2000) (80)
- A Novel MicroRNA-132-Surtuin-1 Axis Underlies Aberrant B-cell Cytokine Regulation in Patients with Relapsing-Remitting Multiple Sclerosis (2014) (80)
- IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation (2016) (79)
- Cytotoxic NKG2C+ CD4 T Cells Target Oligodendrocytes in Multiple Sclerosis (2013) (76)
- Caspase-3-mediated secretion of connective tissue growth factor by apoptotic endothelial cells promotes fibrosis (2010) (74)
- Meningeal Tertiary Lymphoid Tissues and Multiple Sclerosis: A Gathering Place for Diverse Types of Immune Cells during CNS Autoimmunity (2016) (73)
- Dual role of ALCAM in neuroinflammation and blood–brain barrier homeostasis (2017) (71)
- Expression of the ATP-binding Cassette Membrane Transporter, ABCG2, in Human and Rodent Brain Microvessel Endothelial and Glial Cell Culture Systems (2007) (68)
- Characterization of T cell lines derived from glatiramer-acetate-treated multiple sclerosis patients (2000) (68)
- Pathogenesis of multiple sclerosis (2005) (68)
- B7 Expression and Antigen Presentation by Human Brain Endothelial Cells: Requirement for Proinflammatory Cytokines (2000) (66)
- IL-1β enables CNS access to CCR2hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells (2018) (65)
- B Cell-Derived IL-15 Enhances CD8 T Cell Cytotoxicity and Is Increased in Multiple Sclerosis Patients (2011) (64)
- USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation (2016) (64)
- Bradykinin B1 receptor expression and function on T lymphocytes in active multiple sclerosis (1999) (60)
- Functions of lipid raft membrane microdomains at the blood–brain barrier (2009) (60)
- Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis (2019) (58)
- Melanoma cell adhesion molecule–positive CD8 T lymphocytes mediate central nervous system inflammation (2015) (57)
- Lymphocyte migration and multiple sclerosis: Relation with disease course and therapy (1999) (56)
- Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis (2011) (53)
- Th1 and Th2 lymphocyte migration across the human BBB is specifically regulated by interferon beta and copolymer-1. (2005) (53)
- Immunological and pathological characterization of fatal rebound MS activity following natalizumab withdrawal (2017) (52)
- Glial regulation of the blood-brain barrier in health and disease (2015) (51)
- Production of IL‐27 in multiple sclerosis lesions by astrocytes and myeloid cells: Modulation of local immune responses (2016) (49)
- Interferon-gamma secretion by peripheral blood T-cell subsets in multiple sclerosis: correlation with disease phase and interferon-beta therapy. (1999) (48)
- Highly active immunomodulatory therapy ameliorates accumulation of disability in moderately advanced and advanced multiple sclerosis (2016) (47)
- Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry (2019) (47)
- Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia (2021) (46)
- Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis. (2013) (46)
- Risk of secondary progressive multiple sclerosis: A longitudinal study (2020) (45)
- Death receptor expression and function at the human blood brain barrier (2007) (44)
- ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier (2017) (43)
- Use of selective antagonists to dissociate the central cardiovascular and behavioural effects of tachykinins on NK1 and NK2 receptors in the rat (1992) (42)
- Regulation of Cellular and Molecular Trafficking across Human Brain Endothelial Cells by Th1‐ and Th2‐Polarized Lymphocytes (2004) (42)
- Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 (2019) (41)
- Targeting the GM-CSF receptor for the treatment of CNS autoimmunity. (2017) (40)
- T lymphocytes conditioned with Interferon β induce membrane and soluble VCAM on human brain endothelial cells (2001) (39)
- Differential effects of Th1 and Th2 lymphocyte supernatants on human microglia (2003) (38)
- Th1 Polarization of CD4+ T Cells by Toll-Like Receptor 3-Activated Human Microglia (2007) (38)
- An optimized method to process mouse CNS to simultaneously analyze neural cells and leukocytes by flow cytometry (2015) (38)
- Anti-inflammatory disease-modifying treatment and short-term disability progression in SPMS (2017) (38)
- CD70 defines a subset of proinflammatory and CNS-pathogenic TH1/TH17 lymphocytes and is overexpressed in multiple sclerosis (2019) (38)
- Update on treatments in multiple sclerosis. (2015) (36)
- Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis (2018) (35)
- Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology (2019) (35)
- Blood–Brain Barrier Promotes Differentiation of Human Fetal Neural Precursor Cells (2009) (35)
- Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis (2018) (35)
- Managing Multiple Sclerosis: Treatment Initiation, Modification, and Sequencing (2018) (34)
- One more role for the gut: microbiota and blood brain barrier. (2016) (33)
- Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers (2019) (33)
- Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability. (2005) (32)
- Comparative efficacy of first-line natalizumab vs IFN-&bgr; or glatiramer acetate in relapsing MS (2016) (31)
- Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in relapsing-remitting multiple sclerosis patients on high-dose interferon β (2014) (31)
- Roles of the kallikrein/kinin system in the adaptive immune system. (2008) (30)
- Contribution of different relapse phenotypes to disability in multiple sclerosis (2017) (30)
- Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality (2021) (29)
- Antibody-Independent Function of Human B Cells Contributes to Antifungal T Cell Responses (2017) (29)
- JAML mediates monocyte and CD8 T cell migration across the brain endothelium (2015) (29)
- Effect of Disease-Modifying Therapy on Disability in Relapsing-Remitting Multiple Sclerosis Over 15 Years (2020) (29)
- Characterization of the tachykinin receptors involved in spinal and supraspinal cardiovascular regulation. (1995) (29)
- MicroRNA-223 protects neurons from degeneration in experimental autoimmune encephalomyelitis. (2019) (28)
- Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: A contemporary cohort study. (2019) (28)
- EGFL7 reduces CNS inflammation in mouse (2018) (28)
- Early clinical markers of aggressive multiple sclerosis. (2019) (27)
- A roadmap to precision medicine for multiple sclerosis (2020) (26)
- NG2 immunoreactivity on human brain endothelial cells (2001) (25)
- Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis (2018) (25)
- MicroRNA-223 protects neurons from degeneration in Experimental Autoimmune Encephalomyelitis (2018) (23)
- Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites (2020) (23)
- Heterogeneity of T‐lymphocyte function in primary progressive multiple sclerosis: Relation to magnetic resonance imaging lesion volume (2000) (22)
- Regulation of cardiovascular sympathetic neurons by substance P and gamma-aminobutyric acid in the rat spinal cord. (1991) (22)
- Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis (2018) (22)
- Isolation of human brain endothelial cells and characterization of lipid raft-associated proteins by mass spectroscopy. (2011) (21)
- Overcoming the Brain Barriers: From Immune Cells to Nanoparticles. (2019) (21)
- Humanized mouse model of Rasmussen’s encephalitis supports the immune-mediated hypothesis (2018) (21)
- Inflammatory potential and migratory capacities across human brain endothelial cells of distinct glatiramer acetate-reactive T cells generated in treated multiple sclerosis patients. (2004) (21)
- The Blood-Brain Barrier and Its Microenvironment : Basic Physiology to Neurological Disease (2005) (21)
- Subungueal-Splinter Hemorrhage an Early Sign of Thromboangitis Obliterans (1981) (20)
- Isolation of endothelial cells, pericytes and astrocytes from mouse brain (2019) (20)
- Neutrophil-mediated cytotoxicity triggered by immune complexes: the role of reactive oxygen metabolites. (1987) (19)
- Interleukin-26, preferentially produced by TH17 lymphocytes, regulates CNS barrier function (2020) (19)
- Association of Sustained Immunotherapy With Disability Outcomes in Patients With Active Secondary Progressive Multiple Sclerosis. (2020) (19)
- EphrinB1 and EphrinB2 regulate T cell chemotaxis and migration in experimental autoimmune encephalomyelitis and multiple sclerosis (2016) (19)
- Glial Cells as Regulators of Neuroimmune Interactions in the Central Nervous System (2020) (18)
- The efficacy of diflunisal in osteoarthritis of the knee. A Canadian Multicenter Study. (1985) (18)
- Laquinimod enhances central nervous system barrier functions (2017) (17)
- Association of Inflammation and Disability Accrual in Patients With Progressive-Onset Multiple Sclerosis (2018) (17)
- Identification of SARS-CoV-2-specific immune alterations in acutely ill patients (2020) (16)
- Cardiovascular and behavioural effects of centrally administered neuropeptide K in the rat: receptor characterization (1994) (15)
- Delay from treatment start to full effect of immunotherapies for multiple sclerosis. (2020) (15)
- Epstein-Barr virus-associated immune reconstitution inflammatory syndrome as possible cause of fulminant multiple sclerosis relapse after natalizumab interruption (2018) (14)
- QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis. (2020) (14)
- Cyclophosphamide modulates arachidonic acid metabolism by peritoneal macrophages. (1988) (14)
- Human brain endothelial cells supply support for monocyte immunoregulatory functions (2003) (14)
- IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening (2019) (14)
- DICAM promotes TH17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation (2022) (13)
- IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8 (2021) (13)
- Increased superoxide production by polymorphonuclear leukocytes in systemic lupus erythematosus. (1991) (13)
- Frailty in ageing persons with multiple sclerosis (2020) (12)
- Anti‐inflammatory disease‐modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study (2018) (11)
- RNA-binding protein altered expression and mislocalization in MS (2020) (11)
- Risk of requiring a wheelchair in primary progressive multiple sclerosis: Data from the ORATORIO trial and the MSBase registry (2021) (10)
- Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner (2017) (10)
- How safe is natalizumab during pregnancy? (2015) (9)
- Antigen and superantigen presentation in the human CNS (2000) (9)
- Anaesthetic doses of pentobarbital antagonize phosphatidylinositol hydrolysis induced by substance P or carbachol in the spinal cord and cerebral cortex of the rat. (1992) (8)
- Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis (2020) (8)
- Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis (2022) (8)
- Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 (2019) (7)
- Assessing the risk of multiple sclerosis disease-modifying therapies (2019) (7)
- Sex-dependent factors encoded in the immune compartment dictate relapsing or progressive phenotype in demyelinating disease. (2019) (7)
- Productivity loss among people with early multiple sclerosis: A Canadian study (2022) (6)
- Identification of astrocyte regulators by nucleic acid cytometry (2023) (6)
- Interleukin-15 enhances proinflammatory T-cell responses in patients with MS and EAE (2020) (6)
- Induction of B7.1 and B7.2 co-stimulatory molecule on the surface of human brain endothelial cells (1998) (6)
- Bradykinin B1 receptor regulates the migration of lymphocytes in multiple sclerosis (1998) (6)
- The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis (2017) (6)
- Oncostatin M triggers brain inflammation by compromising blood–brain barrier integrity (2022) (6)
- Early Reduction of MRI Activity During 6 Months of Treatment With Cladribine Tablets for Highly Active Relapsing Multiple Sclerosis (2022) (5)
- Endo-MitoEGFP Mice: A Novel Transgenic Mouse with Fluorescently Marked Mitochondria in Microvascular Endothelial Cells (2013) (5)
- IL-37 exerts therapeutic effects in experimental autoimmune 1 encephalomyelitis through the receptor complex IL-1 R 5 / IL-1 R 8 2 (2020) (5)
- Firategrast—natalizumab in a pill? (2012) (5)
- The effectiveness of natalizumab vs fingolimod-A comparison of international registry studies. (2021) (5)
- The risk of relapse following on-treatment clinically silent lesions in patients with relapsing-remitting multiple sclerosis (2017) (4)
- Fundamental mechanistic insights from rare but paradigmatic neuroimmunological diseases (2021) (4)
- Evaluating Soluble EMMPRIN as a Marker of Disease Activity in Multiple Sclerosis: Studies of Serum and Cerebrospinal Fluid (2016) (4)
- Single-cell and spatial RNA sequencing identify perturbators of microglial functions with aging (2022) (4)
- From Baló's concentric sclerosis to multiple sclerosis: a series of 6 patients. (2020) (3)
- Association of Latitude and Exposure to Ultraviolet B Radiation With Severity of Multiple Sclerosis (2022) (3)
- Multiple sclerosis-associated uveitis (2017) (3)
- Natalizumab Versus Fingolimod in Patients with Relapsing-Remitting Multiple Sclerosis: A Subgroup Analysis From Three International Cohorts (2021) (3)
- Effectiveness of fingolimod, dimethyl fumarate and teriflunomide in relapsing-remitting multiple sclerosis: a comparative longitudinal study (2017) (3)
- Stress Signal ULBP4, an NKG2D Ligand, Is Upregulated in Multiple Sclerosis and Shapes CD8+ T-Cell Behaviors (2021) (3)
- Single-Cell Transcriptomics Identifies Brain Endothelium Inflammatory Networks in Experimental Autoimmune Encephalomyelitis (2022) (3)
- Aggressive form of multiple sclerosis can be predicted early after disease onset (2019) (3)
- Treatment Response Score to Glatiramer Acetate or Interferon Beta-1a (2020) (3)
- Determinants of therapeutic lag in multiple sclerosis (2020) (3)
- The IL‐27/IL‐27R axis is altered in CD4+ and CD8+ T lymphocytes from multiple sclerosis patients (2021) (3)
- Sclerosis Patients Cytotoxicity and Is Increased in Multiple B Cell-Derived IL-15 Enhances CD8 T Cell (2014) (3)
- B4GALT6 regulates astrocyte activation during CNS inflammation (INM8P.360) (2015) (3)
- Roles of CD4 and CD8 T Lymphocytes in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis (2015) (2)
- Droplet-based forward genetic screening of astrocyte–microglia cross-talk (2023) (2)
- Immunotherapy prevents long-term disability in relapsing multiple sclerosis over 15 years (2019) (2)
- OR.81. Astrocyte-secreted Sonic Hedgehog Supports CNS Anti-inflammatory Activity and Promotes Optimal Human Blood Brain Barrier Functioning (2009) (2)
- IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes (2022) (2)
- The efficacy of diflunisal in osteoarthritis of the knee: an extended study. (1986) (2)
- Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a (2016) (2)
- OR.21. MCAM/CD146 is Expressed by Brain Endothelial Cells and Defines a Unique Effector Memory Lymphocyte Subset Involved in Neuroinflammation (2009) (2)
- Ephrin B1 and B2 are essential for the pathogenicity and migration capacity of TH17 cells in EAE and MS (2014) (2)
- Oxidative Modifications of Parkin Underlie its Selective Neuroprotection in Adult Human Brain (2020) (2)
- Neuropeptide K potently stimulates the hydrolysis of phosphatidylinositol in the rat spinal cord (1993) (2)
- The Hedgehog Pathway Sustains Blood–brain Barrier Properties and Promotes CNS Immune Quiescence (2010) (2)
- Comparative effectiveness of switching to natalizumab or fingolimod after relapse on first-line relapsing-remitting multiple sclerosis therapy: propensity score matching analysis from the MSBase registry (2018) (1)
- Early clinical predictors of severe MS (2018) (1)
- Immune Functions of Brain Endothelial Cells (2005) (1)
- Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology (2019) (1)
- The CNS barriers differentially regulate the migration of B cells (2014) (1)
- CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis (2022) (1)
- Ninjurin-1 Controls the Recruitment of Antigen-presenting Cells to the CNS and the Development of Neuroinflammation (2010) (1)
- Characterization of the cardiovascular and behavioral effects of centrally administered neuropeptide K in the conscious rat (1993) (1)
- DICAM: A novel molecular effector in neuroinflammation (2014) (1)
- Disease Reactivation After Cessation of Disease-Modifying Therapy in Patients With Relapsing-Remitting Multiple Sclerosis (2022) (1)
- Inflammation at the Blood–Brain Barrier in Multiple Sclerosis (2013) (1)
- Integrin alpha8 is a novel mediator of T lymphocyte migration across the CNS barriers. (2016) (1)
- Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation (2016) (1)
- The Canadian prospective cohort study to understand progression in multiple sclerosis (CanProCo): rationale, aims, and study design (2021) (1)
- [Neutrophil-dependent inflammatory reactions in systemic lupus erythematosus]. (1989) (1)
- Diverse injury responses of human oligodendrocyte to mediators implicated in multiple sclerosis. (2022) (1)
- A case of aggressive pediatric multiple sclerosis successfully treated with an autologous hematopoietic stem cell transplant (2018) (1)
- THUR 174 The magnify-ms study: mavenclad® tablets in active rms (2018) (1)
- The TH17-associated cytokine interleukin-26 regulates barrier function during neuroinflammation (2015) (1)
- Anti-inflammatory disease modifying treatment does not attenuate disability progression in secondary progressive multiple sclerosis (2016) (1)
- Multiple Sclerosis Severity Score (MSSS) improves the accuracy of individualized prediction in MS (2022) (1)
- In vivo characterization of tachykinin receptors responsible for the central cardiovascular effects of substance P and neurokinin A (1993) (1)
- Determinants of MS re-activation after discontinuing therapies (2018) (1)
- 10-year progression predictors after first treatment initiation in a relapsing-remitting MS cohort (2015) (1)
- Specific Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged Efficacy of Cladribine Tablets (2022) (1)
- Characterization of the cardiovascular and behavioral effects of centrally administered neuropeptide K in the conscious rat (1992) (1)
- MCAM/CD146 Defines and Regulates the Function of a Population of Human Effector Memory Th17 Lymphocytes Subset Involved in Neuroinflammation (2010) (1)
- Special issue on molecular basis of multiple sclerosis. (2011) (1)
- CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein–Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response (2021) (1)
- Late Breaking News Abstracts. (2017) (1)
- Successful Management of Natalizumab-Associated Primary Central Nervous System Lymphoma through Autologous Stem Cell Transplant (2020) (1)
- OR.92. Human Glioblastoma Cancer Stem Cells Promote Intra-tumoral Immune Regulatory Functions (2009) (1)
- Comparative effectiveness in multiple sclerosis: A methodological comparison (2023) (1)
- Nascent Multiple Sclerosis Lesions are Associated with Early Disturbances in the Blood–brain Barrier (2010) (0)
- Integrin alpha8 is a novel mediator of activated, proinflammatory T lymphocyte migration across the CNS barriers (2018) (0)
- Hexameric Soluble Form of Pathogenic Protein from Human Endogenous Retrovirus (pHERV-W-Env) Specifically Extracted from MS Lesions. (2018) (0)
- Reply (2000) (0)
- OR.18. VLA-4-Dependent Recruitment of Effector Memory CD8+T Lymphocytes into the Central Nervous System (2009) (0)
- Switching to natalizumab or fingolimod in multiple sclerosis: Comparative effectiveness and effect of pre-switch disease activity. (2022) (0)
- Enhanced levels of IL-27 and IL-27R in the central nervous system of multiple sclerosis patients (2014) (0)
- Comparative effectiveness of natalizumab and fingolimod in different subgroups of patients with relapsing-remitting multiple sclerosis (2019) (0)
- A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile (2022) (0)
- Pregnancy protects against long-term disability accrual in relapsing-remitting MS (2016) (0)
- MSJ926955_appendix_2 – Supplemental material for Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis (2020) (0)
- Human Blood–brain Barrier-associated DCs Originate from Blood Monocytes and Polarize CD4+ Lymphocytes into Th17 or Th1 (2007) (0)
- GM-CSF upregulates IL-15 expression on specific human myeloid cells. (2017) (0)
- University of Montreal's Clinician-Investigator Program: A 10-Year Descriptive Evaluation. (2022) (0)
- Monocyte Migration Across the Blood–Brain Barrier: Implications for New Lesion Formation in Multiple Sclerosis (2005) (0)
- Individual response to disease modifying therapies: a global observational cohort study (2016) (0)
- ALCAM regulates BBB integrity and neuroinflammation (2014) (0)
- MAFG-driven astrocytes promote CNS inflammation (2020) (0)
- Granulocyte–macrophage colony‐stimulating factor–stimulated human macrophages demonstrate enhanced functions contributing to T‐cell activation (2022) (0)
- Predicting long-term sustained disability progression in multiple sclerosis (2019) (0)
- Human B cell and glial cell interactions: Implications to the compartmentalized CNS inflammation of multiple sclerosis (MS) (2014) (0)
- MCAM Identifies Encephalitogenic TH17 Lymphocytes and Promotes Their Recruitment to the CNS (SC02.001) (2012) (0)
- PND18 - PROGRESSION OF DISABILITY IN PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS: A RETROSPECTIVE COHORT STUDY USING DATA FROM THE MSBASE REGISTRY AND A CONTEXTUALISATION WITH AN EXISTING NATURAL HISTORY DATASET (2018) (0)
- Comparing switch to ocrelizumab, cladribine or natalizumab after fingolimod treatment cessation in multiple sclerosis (2022) (0)
- Human CD4 and CD8 T cells distinctly upregulate Suppressors of Cytokine Signaling 1 and 3 following Interferon-β treatment. (117.24) (2011) (0)
- of Therapeutic Lag in Relapsing Multiple Sclerosis (2020) (0)
- The brain under immune attack : Who presents the antigen? (1999) (0)
- OR.96. The Abrogation of Inflammatory Disease Activity in MS Patients Treated with Immune Ablation and Autologous Haematopoetic Stem-cell Transplantation (AHSCT) is Associated with Significant Decreases in ThIL-17, but not Th1 Responses (2008) (0)
- MCAM identifies inflammatory encephalitogenic CD8 T lymphocytes presenting a high cytotoxic capacity (2014) (0)
- OR.17. Ninjurin-1 is a Novel Adhesion Molecule of the Blood-brain Barrier Involved in the Recruitment of Monocytes to the Central Nervous System (2009) (0)
- ‘Cytokine defined’ B cell subsets in multiple sclerosis (2014) (0)
- Mcam modulation and uses thereof in the management of neuroinflammatory conditions (2009) (0)
- ALCAM is a Novel Adhesion Molecule of the Inflammed Endothelium Involved in Leukocyte Trafficking to the Central Nervous System (2007) (0)
- Confirmed disability progression as a marker of permanent disability in multiple sclerosis (2022) (0)
- Variability of the response to immunotherapy among subgroups of patients with multiple sclerosis (2023) (0)
- Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis (2018) (0)
- Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis (2018) (0)
- Stoichiometric Ratios of Reactive Oxygen Species Production by Polymorphonuclear Leukocites (1993) (0)
- Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis (2022) (0)
- Personalizing treatment effect based on patient's baseline profile: a statistical modelling approach applied to randomized clinical trial and observational study data (2019) (0)
- The novel TH17-associated cytokine IL-26 mediates BBB breakdown and neuroinflammation (2014) (0)
- Development and characterization of a novel mouse model of Rasmussen's encephalitis (2014) (0)
- Effects of Laquinimod on the Human Blood-Brain Barrier (P02.118) (2012) (0)
- Early predictors of disability in paediatric multiple sclerosis: evidence from a multi-national registry (2022) (0)
- TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types (2018) (0)
- Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 (2019) (0)
- Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 (2019) (0)
- CD70 defines a subset of proinflammatory and CNS-pathogenic TH1/TH17 lymphocytes and is overexpressed in multiple sclerosis (2019) (0)
- Interpericyte tunnelling nanotubes regulate neurovascular coupling (2020) (0)
- Speci fi c Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged E ffi cacy of Cladribine Tablets A MAGNIFY-MS Substudy (0)
- OP 4.3 – 00112 Leaky reservoirs are associated with HIV-specific cd4 and CD8 T-cell responses (2022) (0)
- Immunotherapies Improve Long-Term Disability Outcomes in Relapsing-Remitting Multiple Sclerosis (2020) (0)
- Early onset of Action and Sustained Efficacy of MRI Outcomes during Cladribine Tablets Treatment in Highly Active Relapsing Multiple Sclerosis: Results of the 2-Year MAGNIFY-MS Study (2023) (0)
- Blood Biomarker Dynamics in Highly Active Relapsing Multiple Sclerosis Patients Treated With Cladribine Tablets: Results of the 2-Year MAGNIFY-MS Study (S16.006) (2023) (0)
- Specific alterations in NKG2D+ T lymphocytes in relapsing-remitting and progressive multiple sclerosis patients (2023) (0)
- F.24. Inflamed CNS-Endothelial Barrier Promotes Recruitment of Effector Memory CD8+ T Lymphocytes (2008) (0)
- MSJ926955_supplementary_material – Supplemental material for Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis (2020) (0)
- Determinants of therapeutic lag in relapsing multiple sclerosis (2019) (0)
- ORAL PRESENTATIONS (2003) (0)
- Human CD4 and CD8 T cells distinctly upregulate Suppressors of Cytokine Signaling 1 and 3 following Interferon-{beta} treatment. (2011) (0)
- MCAM+ brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4+ T lymphocytes (2022) (0)
- IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes (2022) (0)
- Tau seeding in cases of multiple sclerosis (2022) (0)
- Granulocyte Recruitment Blood-Brain Barrier Permeability and Optica-IgG Astrocyte Interactions on Functional Consequences of Neuromyelitis (2008) (0)
- The impact of IL-27 on human T cells is altered in multiple sclerosis patients (2017) (0)
- Glial regulation of the blood-brain barrier in health and disease (2015) (0)
- Netrin-1 regulates blood–brain barrier function and CNS inflammation (2014) (0)
- Erratum: Puscas, I.; et al. IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening. Pharmaceutics 2019, 11, 587 (2020) (0)
- Employment status, productivity loss, and associated factors among people with multiple sclerosis. (2023) (0)
- Interferon-beta up-regulates suppressor of cytokine signaling 1 in T cells of multiple sclerosis patients (2013) (0)
- Disability accrual in primary and secondary progressive multiple sclerosis (2023) (0)
- IL-24 is produced both locally and peripherally by activated immune cells of MS patients (2017) (0)
- MSJ926955_STROBE_checklist – Supplemental material for Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis (2020) (0)
- Modifiers of the effectiveness of MS immunotherapies (2019) (0)
- Neuroinflammatory Diseases Barrier Disruption in Demyelinating Spinal Cord - Neutrophils Mediate Blood (2014) (0)
- Pregnancy incidence and therapy exposure in relapsing forms of MS: a 12-year retrospective multicentre analysis (2017) (0)
- Site-directed mutagenesis studies of h 15-LOX-1 and their effects on inhibitor potency (2015) (0)
- RNA-binding protein altered expression and mislocalization in multiple sclerosis (2019) (0)
- IL-15 expression on B cells and myeloid cells is distinctly modulated by inflammatory factors in MS and healthy donors (2019) (0)
- Elevated functional Interleukin-15 provided by human peripheral immune cells in Multiple Sclerosis patients (150.8) (2011) (0)
- Early non-disabling relapses are important predictors of disability accumulation in people with relapsing-remitting multiple sclerosis. (2023) (0)
- Functional analyses of transmigrated monocyte-derived CD123+ dendritic cells across the inflamed blood–brain barrier endothelium (2014) (0)
- OR.56. Preferential Recruitment of IL-17 and IFN-γ Co-expressing CD4+T Lymphocytes Into the Central Nervous System (2009) (0)
- Interleukin-24, produced by both TH lymphocytes and astrocytes, decreases blood brain barrier function (2015) (0)
- EGFL7 reduces CNS inflammation in mouse (2018) (0)
- 3-Dimensional Immunostaining and Automated Deep-Learning Based Analysis of Nerve Degeneration (2022) (0)
- MCAM in Multiple Sclerosis: a biomarker of disease activity? (P1.381) (2017) (0)
- Cytotoxic Human IL-22-expressing Th17 Lymphocytes Promote Immune Cell Migration Into the Central Nervous System (2007) (0)
- Across Brain Endothelial Cells Determinants of Human B Cell Migration (0)
- Characterizing the role of integrin alpha8 in mediating CD4+ T lymphocyte migration across the blood–brain barrier in multiple sclerosis (2014) (0)
- Role of PD-L1/PD-L2 expression by human brain endothelial cells in regulating T cell responses in the context of Multiple Sclerosis. (44.6) (2011) (0)
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What Schools Are Affiliated With Alexandre Prat?
Alexandre Prat is affiliated with the following schools:
