Alexey Teplyakov

Alexey Teplyakov's AcademicInfluence.com Rankings

Alexey Teplyakov

Chemistry

#4666

World Rank

#5753

Historical Rank

Physical Chemistry

#723

World Rank

#778

Historical Rank

chemistry Degrees

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Chemistry

Alexey Teplyakov's Degrees

PhD Chemistry University of California, Berkeley
Masters Chemistry Moscow State University
Bachelors Chemistry Moscow State University

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Alexey Teplyakov's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

MOLREP: an Automated Program for Molecular Replacement (1997) (4523)
Molecular replacement with MOLREP. (2010) (2886)
An approach to multi-copy search in molecular replacement. (2000) (696)
Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2. (1996) (246)
Antibody Structure and Function: The Basis for Engineering Therapeutics (2019) (177)
Structure-based engineering of a monoclonal antibody for improved solubility. (2010) (174)
Crystal structure of thermitase at 1.4 A resolution. (1990) (133)
Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 A crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase. (1996) (123)
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations. (2014) (122)
Second antibody modeling assessment (AMA‐II) (2014) (118)
Channeling of ammonia in glucosamine-6-phosphate synthase. (2001) (115)
Antibody modeling assessment (2011) (110)
Involvement of the C terminus in intramolecular nitrogen channeling in glucosamine 6-phosphate synthase: evidence from a 1.6 A crystal structure of the isomerase domain. (1998) (97)
Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab. (2010) (93)
Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase (2001) (92)
An unusual route to thermostability disclosed by the comparison of thermus thermophilus and escherichia coli inorganic pyrophosphatases (1996) (77)
The mechanism of sugar phosphate isomerization by glucosamine 6‐phosphate synthase (2008) (76)
Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p). (1993) (74)
Mechanisms of self-association of a human monoclonal antibody CNTO607. (2012) (70)
Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein (2006) (70)
Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8 (2016) (66)
Design of novel FN3 domains with high stability by a consensus sequence approach. (2012) (64)
The structure of deoxy- and oxy-leghaemoglobin from lupin. (1995) (63)
Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris. (1992) (57)
IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface. (2013) (55)
Crystal structure of inorganic pyrophosphatase from Thermus thermophilus (1994) (55)
X-ray structure of yeast inorganic pyrophosphatase complexed with manganese and phosphate. (1996) (55)
Crystal Structure of the YchF Protein Reveals Binding Sites for GTP and Nucleic Acid (2003) (55)
Crystal structure of neurotoxin Ts1 from Tityus serrulatus provides insights into the specificity and toxicity of scorpion toxins. (1999) (53)
Antibody modeling assessment II. Structures and models (2014) (52)
Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p). (1995) (51)
Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site (2003) (50)
Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes. (1990) (49)
Structural diversity in a human antibody germline library (2016) (47)
Crystal structure of the YjeE protein from Haemophilus influenzae: A putative Atpase involved in cell wall synthesis (2002) (46)
Evidence for a novel GTPase priming step in the SRP protein targeting pathway (2001) (46)
From Lobry de Bruyn to enzyme-catalyzed ammonia channelling: molecular studies of D-glucosamine-6P synthase. (2002) (43)
Promoting crystallization of antibody–antigen complexes via microseed matrix screening (2010) (42)
The binding of carbon monoxide and nitric oxide to leghaemoglobin in comparison with other haemoglobins. (1996) (38)
Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure. (2012) (37)
A translation-function approach for heavy-atom location in macromolecular crystallography. (1998) (37)
Human framework adaptation of a mouse anti-human IL-13 antibody. (2010) (37)
Crystal structure of the high-alkaline serine protease PB92 from Bacillus alcalophilus. (1992) (36)
Crystal structure of dephospho-coenzyme A kinase from Haemophilus influenzae. (2001) (35)
Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607. (2009) (34)
Crystal Structure of the YgfZ Protein from Escherichia coli Suggests a Folate-Dependent Regulatory Role in One-Carbon Metabolism (2004) (34)
Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution. (1997) (33)
Crystal structure of apo-neocarzinostatin at 0.15-nm resolution. (1993) (32)
Protein engineering of the high-alkaline serine protease PB92 from Bacillus alcalophilus: functional and structural consequences of mutation at the S4 substrate binding pocket. (1992) (31)
Crystal structure of bacteriophage T4 deoxynucleotide kinase with its substrates dGMP and ATP. (1996) (31)
Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site (2003) (30)
Crystal structure of the Escherichia coli YjiA protein suggests a GTP‐dependent regulatory function (2003) (25)
Development of a CD123xCD3 Bispecific Antibody (JNJ-63709178) for the Treatment of Acute Myeloid Leukemia (AML) (2016) (25)
High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate. (1993) (24)
Crystal Structure of the Bacterial YhcH Protein Indicates a Role in Sialic Acid Catabolism (2005) (24)
Structure of the EMMPRIN N‐terminal domain 1: Dimerization via β‐strand swapping (2009) (23)
Protein crystallization with microseed matrix screening: application to human germline antibody Fabs (2014) (22)
Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. (2012) (22)
Crystallization and preliminary X-ray analysis of the two domains of glucosamine-6-phosphate synthase from Escherichia coli. (1994) (22)
Crystal structure of B‐cell co‐receptor CD19 in complex with antibody B43 reveals an unexpected fold (2018) (21)
Coevolution of antibody stability and Vκ CDR-L3 canonical structure. (2010) (20)
Crystal structure of the petal death protein from carnation flower. (2005) (18)
Effects of eglin‐c binding to thermitase: Three‐dimensional structure comparison of native thermitase and thermitase eglin‐c complexes (1992) (18)
Molecular cloning, expression, and site-directed mutagenesis of inorganic pyrophosphatase from Thermus thermophilus HB8. (1998) (17)
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge (2014) (16)
Antigen recognition by antibody C836 through adjustment of V(L)/V(H) packing. (2011) (16)
The ultimate wavelength for protein crystallography? (1997) (15)
Canonical structures of short CDR-L3 in antibodies (2014) (13)
Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains (2004) (11)
Synthesis by native chemical ligation and crystal structure of human CCL2 (2010) (10)
Crystallization of a challenging antigen-antibody complex: TLR3 ECD with three noncompeting Fabs. (2011) (10)
Crystal structure of tissue factor in complex with antibody 10H10 reveals the signaling epitope. (2017) (9)
C‐terminal β‐strand swapping in a consensus‐derived fibronectin Type III scaffold (2014) (9)
Structural insights into humanization of anti-tissue factor antibody 10H10 (2018) (9)
Crystal structure of thermitase from Thermoactinomyces vulgaris at 2.2 Å resolution (1989) (9)
Assisting functional assignment for hypothetical Heamophilus influenzae gene products through structural genomics. (2002) (9)
Crystal structure of human germline antibody 3-23/B3. (2011) (9)
On the conformation of Phe78 of a chromoprotein antibiotic, neocarzinostatin. (1995) (8)
Crystal structure of CD27 in complex with a neutralizing noncompeting antibody (2017) (8)
From Lobry de Bruyn to Enzyme‐Catalyzed Ammonia Channelling: Molecular Studies of D‐Glucosamine‐6P Synthase (2002) (7)
Purification, crystallization and preliminary X-ray analysis of inorganic pyrophosphatase from Thermus thermophilus. (1993) (7)
Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function (2004) (7)
Conformational flexibility of an anti-IL-13 DARPin† (2016) (7)
Preliminary X-ray study of naproxen esterase from Bacillus subtilis. (1993) (7)
Crystal structure of the Escherichia coli Tas protein, an NADP(H)‐dependent aldo‐keto reductase (2003) (7)
On the domain pairing in chimeric antibodies. (2010) (6)
Crystal structure of MnPi complex of inorganic pyrophosphatase of yeast at resolution of 2.35 Å (1991) (6)
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody. (2020) (6)
Structural evidence for a constrained conformation of short CDR‐L3 in antibodies (2014) (5)
Epitope‐dependent mechanisms of CD27 neutralization revealed by X‐ray crystallography (2017) (5)
On the choice of an optimal wavelength in macromolecular crystallography. (1998) (5)
His‐tag binding by antibody C706 mimics β‐amyloid recognition (2011) (4)
N‐terminal β‐strand swapping in a consensus‐derived alternative scaffold driven by stabilizing hydrophobic interactions (2014) (4)
Structural insights into chemokine CCL17 recognition by antibody M116 (2017) (4)
Crystallographic study of eglin-C binding to thermitase. (1996) (3)
THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE (1994) (3)
A coiled conformation of amyloid-β recognized by antibody C706 (2017) (3)
Induced conformational change in human IL‐4 upon binding of a signal‐neutralizing DARPin (2015) (3)
Preliminary crystallographic study of cyclohexadienyl dehydratase from Pseudomonas aeruginosa. (1993) (3)
STRUCTURE OF INORGANIC PYROPHOSPHATASE (1997) (2)
CRYSTAL STRUCTURE OF THERMITASE AT 1.4 ANGSTROMS RESOLUTION (1994) (2)
Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 Å (1996) (2)
Crystal Structure of IL-17A/Fab6785 complex (2015) (1)
Structure of phosphorylated Enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system (2006) (1)
Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088. (2010) (1)
Structural genomics of DNA damage response in Escherichia coli (2004) (1)
Chapter 13.5 Molecular replacement with MOLREP (2012) (1)
Crystallization and preliminary X-ray analysis of bacteriophage T4 deoxynucleotide kinase. (1996) (1)
ADP-ribosyltransferase C3bot2 from Clostridium botulinum, monoclinic form (2004) (0)
COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177 (2017) (0)
DEPHOSPHO-COA KINASE IN COMPLEX WITH ATP (2002) (0)
TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH (2003) (0)
Structure of anti-TAU AT8 FAB in the presence of phosphopeptide (2016) (0)
Structure of IL-13 antibody H2L6, A humanized variant OF C836 (2010) (0)
Crystal structure of chimeric antibody X836 (2010) (0)
Crystal structure of the complex between IL-13 and M1295 FAB (2010) (0)
Crystal structure of TENCON variant G10 (2014) (0)
Surface salt bridges contribute to the extreme thermal stability of an FN3‐like domain from a thermophilic bacterium (2021) (0)
CRYSTAL STRUCTURE OF DARPIN 44C12V5 IN COMPLEX WITH HUMAN IL-4 (2015) (0)
DEOXYNUCLEOSIDE MONOPHOSPHATE KINASE COMPLEXED WITH DEOXY-GMP AND AMP (1997) (0)
Crystal structure of anti-emmprin antibody 4A5 Fab in trigonal form (2014) (0)
COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND H2191 (2017) (0)
Structure determination of glucosamine-6P synthase: fighting against pseudosymmetry (1996) (0)
GLUCOSAMINE 6-PHOSPHATE SYNTHASE WITH GLUCOSE 6-PHOSPHATE (2001) (0)
Crystal structure of the QAA variant of anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide (2014) (0)
GLUTAMINASE DOMAIN OF GLUCOSAMINE 6-PHOSPHATE SYNTHASE COMPLEXED WITH GLUTAMATE (1996) (0)
YFFB (PA3664) PROTEIN (2004) (0)
agonistic antibodies that bind specifically to human CD40 and methods of use. (2018) (0)
Crystal structure of fc-fragment of human IgG2-Sigma antibody (2013) (0)
CRYSTAL STRUCTURE OF ANTI-IL4 DARPIN 44C12V5 (2015) (0)
ISOMERASE DOMAIN OF GLUCOSAMINE 6-PHOSPHATE SYNTHASE COMPLEXED WITH GLUCOSAMINE 6-PHOSPHATE (1998) (0)
Crystal structure of anti-mcp-1 antibody cnto888 (2012) (0)
YCDX PROTEIN, TRINUCLEAR ZINC SITE (2003) (0)
X-ray Structure Investigation of some Pyridoxal-Containing Enzymes (1991) (0)
Structural genomics, ybgI protein, unknown function (2004) (0)
Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form) (2013) (0)
Structure of the bacterial YhcH protein, a putative copper aminosugar epimerase (2005) (0)
An unusual route to thermostability in pyrophosphatases (1996) (0)
Beta-d-xylosidase (selenomethionine) XYND from Clostridium Acetobutylicum (2005) (0)
THE YJEE PROTEIN (2002) (0)
Crystal structure of anti-IL-23 antibody CNTO1959 at pH 6.5 (2014) (0)
COMPLEX OF HI0065 WITH ADP AND MAGNESIUM (2002) (0)
Crystal structure of anti-hinge rabbit antibody C2095 (2014) (0)
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV1-39 (2016) (0)
DEOXYNUCLEOSIDE MONOPHOSPHATE KINASE COMPLEXED WITH DEOXY-GMP (1997) (0)
YCHF PROTEIN (HI0393) (2003) (0)
Crystal structure of anti-beta-amyloid antibody C705 (2011) (0)
Crystal structure of fibcon (2012) (0)
ISOMERASE DOMAIN OF GLUCOSAMINE 6-PHOSPHATE SYNTHASE COMPLEXED WITH 2-AMINO-2-DEOXYGLUCITOL 6-PHOSPHATE (1999) (0)
YHCH PROTEIN (HI0227) COPPER COMPLEX (2005) (0)
Channeling of ammonia in glucosamine-6P synthase (2000) (0)
Crystal structure of Anti-IL-17A antibody CNTO3186 (2014) (0)
Toll-like receptor antagonists 3 (2010) (0)
Crystal structure of monomeric TENCON variant P54CR4-31 (2014) (0)
Crystal structure of the complex between human tissue factor extracellular domain and antibody 10H10 FAB fragment (2014) (0)
BETA-D-XYLOSIDASE, A FAMILY 43 GLYCOSIDE HYDROLASE (2005) (0)
CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13 (2016) (0)
A coiled conformation of amyloid-β recognized by antibody C706 (2017) (0)
Anti-beta-amyloid antibody c706 fab in space group P21 (2010) (0)
GLUTAMINASE DOMAIN OF GLUCOSAMINE 6-PHOSPHATE SYNTHASE COMPLEXED WITH L-GLU HYDROXAMATE (1996) (0)
Cover Image, Volume 86, Issue 5 (2022) (0)
Structure of quaternary complex of human TLR3ecd with three Fabs (Form2) (2012) (0)
YCDX PROTEIN IN AUTOINHIBITED STATE (2004) (0)
CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE (2020) (0)
Crystal structure of D-amino acid oxidase: A case of active site mirror-image convergent evolution with flavocytochrome b2 (density (2005) (0)
Crystal structure of TENCON variant P41BR3-42 (2014) (0)
NEUROTOXIN (TS1) FROM BRAZILIAN SCORPION TITYUS SERRULATUS (1999) (0)
Structure of quaternary complex of human TLR3ecd with three Fabs (Form1) (2012) (0)
The “Overkill” Phenomenon in Russian History (2021) (0)
CRYSTAL STRUCTURE OF ANTI-CCL17 ANTIBODY M116 (2017) (0)
Crystal structure of the complex between CNTO607 Fab and IL-13 (2009) (0)
Methods of reducing clinical symptoms of viral infection by administering a toll-like receptor 3 antagonist (2016) (0)
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV1-39 (2016) (0)
Crystal structure of anti-TAU antibody AT8 FAB (2016) (0)
Crystal structure of fc-fragment of human IgG2 antibody (centered crystal form) (2013) (0)
Crystal Structure of Human Germline Antibody 1-69/B3 (2011) (0)
Human synthetic monocyte chemoattractant protein 1 (MCP-1) (2009) (0)
Mayakovsky, the Briks, and the Chekists (2019) (0)
COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB (2018) (0)
Structural genomics, protein ybgI, unknown function (2004) (0)
Crystal structure of anti-ST2L antibody C2244 (2014) (0)
CRYSTAL STRUCTURE OF ANTI-IL-13 DARPIN 6G9 (2016) (0)
Crystal structure of Fab12 (2012) (0)
Crystal structure of human germline antibody 5-51/O12 (2014) (0)
“Stapling” scFv for multispecific biotherapeutics of superior properties (2023) (0)
Abstract 1492: Development of a CD123xCD3 bispecific antibody to treat acute myeloid leukemia (AML) (2016) (0)
“Red Funeral”. New Funeral Rites in Early Soviet Russia (2021) (0)
Anti-TAU AT8 FAB with doubly phosphorylated TAU peptide (2016) (0)
Crystal structure of the anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide (2014) (0)
Crystal structure of anti-NGF antibody CNTO7309 (2014) (0)
YAJQ PROTEIN (HI1034) (2003) (0)
Crystal structure of ANTI-IL-13 antibody C836 (2010) (0)
Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase (2001) (0)
ANTI-TISSUE FACTOR ANTIBODY M59, A HUMANIZED VERSION OF 10H10 (2017) (0)
CRYSTAL STRUCTURE OF ANTI-CD19 ANTIBODY B43 FAB (2018) (0)
Crystal structure of anti-IL-23 antibody CNTO1959 at pH 9.5 (2014) (0)
YHCH protein (HI0227) (2003) (0)
Abstract 3813: Development of JNJ-64164711, a low fucose anti-GITR antibody for enhanced depletion of tumor regulatory T cells (Tregs) (2018) (0)
Crystal structure of ANTI-TLR3 antibody C1068 FAB (2011) (0)
Crystal structure of TENCON variant P40AR2-32R2 (2014) (0)
Petal death protein PSR132 with cysteine-linked glutaraldehyde forming a thiohemiacetal adduct (2006) (0)
Crystal structure of anti-emmprin antibody 5F6 FAB (2011) (0)
Anti-ccl17-antikörper (2014) (0)
Crystal Structure of Tencon (2012) (0)
HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587 (2017) (0)
Structural and functional consequences of engineering the high alkaline serine protease PB92. (1996) (0)
Crystal structure of Anti-IL-17A antibody CNTO7357 (2009) (0)
Crystal structure of Fab C2507 (2011) (0)
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB (2017) (0)
Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a (2012) (0)
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-11 (2016) (0)
ANTIBODY C706 IN COMPLEX WTH BETA-AMYLOID PEPTIDE 1-16 (2017) (0)
Crystal structure of anti-tissue factor antibody 10H10 (2014) (0)

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What Schools Are Affiliated With Alexey Teplyakov?

Alexey Teplyakov is affiliated with the following schools:

Moscow State University
University of California, Berkeley
University of Pavia
Stanford University
Moscow State University