Alfred E. Chang
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(Suggest an Edit or Addition)Alfred E. Chang's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. (1987) (2783)
- Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer. (1985) (2506)
- Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. (1998) (1339)
- Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. (1993) (873)
- Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. (2009) (734)
- Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer. (1993) (615)
- A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases. (1987) (537)
- High-dose recombinant interleukin 2 in the treatment of patients with disseminated cancer. Responses, treatment-related morbidity, and histologic findings. (1986) (488)
- The neuropsychiatric effects of treatment with interleukin-2 and lymphokine-activated killer cells. (1987) (457)
- Reappraisal of hepatic arterial infusion in the treatment of nonresectable liver metastases from colorectal cancer. (1996) (441)
- Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis. (1998) (440)
- Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study. (1988) (435)
- Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment1 (2007) (432)
- Roles of activated Src and Stat3 signaling in melanoma tumor cell growth (2002) (426)
- Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression. (2001) (335)
- Mitotic Rate and Younger Age Are Predictors of Sentinel Lymph Node Positivity: Lessons Learned From the Generation of a Probabilistic Model (2004) (311)
- IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer (2011) (249)
- Perioperative blood transfusions are associated with decreased time to recurrence and decreased survival after resection of colorectal liver metastases. (1988) (244)
- Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. (1996) (240)
- Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2. (1991) (239)
- A phase I trial of tumor lysate-pulsed dendritic cells in the treatment of advanced cancer. (2002) (234)
- Delata-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. A prospective, randomized evaluation. (1979) (208)
- Comparison of computed and conventional whole lung tomography in detecting pulmonary nodules: a prospective radiologic-pathologic study. (1978) (207)
- Current Status and Future Directions (2013) (206)
- Cancer stem cell vaccination confers significant antitumor immunity. (2012) (194)
- Metabolic imaging of human extremity musculoskeletal tumors by PET. (1988) (191)
- FOXP3 defines regulatory T cells in human tumor and autoimmune disease. (2009) (188)
- The impact of factors beyond Breslow depth on predicting sentinel lymph node positivity in melanoma (2007) (182)
- Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling. (2016) (180)
- Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2. (1997) (176)
- Evaluation of computed tomography in the detection of pulmonary metastases. A prospective study (1979) (165)
- Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma. (2007) (159)
- Clinicopathologic features of metastasis in nonsentinel lymph nodes of breast carcinoma patients (2003) (159)
- Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration. (2003) (157)
- Sentinel Lymph Node Biopsy Performed After Neoadjuvant Chemotherapy is Accurate in Patients with Documented Node-Positive Breast Cancer at Presentation (2007) (153)
- Defining the critical hurdles in cancer immunotherapy (2011) (152)
- Immunologic response to cryoablation of breast cancer (2005) (151)
- Adjuvant chemotherapy for patients with high-grade soft-tissue sarcomas of the extremity. (1988) (147)
- Type 1 versus type 2 cytokine release by Vbeta T cell subpopulations determines in vivo antitumor reactivity: IL-10 mediates a suppressive role. (1997) (137)
- Oncology : an evidence-based approach (2006) (136)
- Predictors of nonsentinel lymph node positivity in patients with a positive sentinel node for melanoma. (2005) (134)
- The systemic administration of purified interleukin 2 enhances the ability of sensitized murine lymphocytes to cure a disseminated syngeneic lymphoma. (1984) (133)
- Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma. (2014) (133)
- Concise Review: Targeting Cancer Stem Cells Using Immunologic Approaches (2015) (129)
- Anti-CD137 Monoclonal Antibody Administration Augments the Antitumor Efficacy of Dendritic Cell-Based Vaccines (2004) (122)
- Adoptive Transfer of Tumor Reactive B Cells Confers Host T-Cell Immunity and Tumor Regression (2011) (120)
- Sentinel node biopsy prior to neoadjuvant chemotherapy. (2003) (114)
- In Vivo Sensitized and In Vitro Activated B Cells Mediate Tumor Regression in Cancer Adoptive Immunotherapy1 (2009) (114)
- Liver metastasis detection: comparative sensitivities of MR imaging and CT scanning. (1987) (112)
- Magnetic Resonance Imaging Versus Computed Tomography in the Evaluation of Soft Tissue Tumors of the Extremities (1987) (112)
- Generation of therapeutic T lymphocytes from tumor-bearing mice by in vitro sensitization. Culture requirements and characterization of immunologic specificity. (1988) (109)
- Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer. (2003) (109)
- Inguinal node dissection for melanoma in the era of sentinel lymph node biopsy. (2007) (104)
- A new approach to the therapy of cancer based on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2. (1986) (102)
- Activating STAT6 mutations in follicular lymphoma. (2015) (101)
- Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma. (1994) (101)
- Treatment of solid tumours in children with tumour-lysate-pulsed dendritic cells (2000) (101)
- Interleukin 2 and psoriasis. (1988) (98)
- Clinical observations on adoptive immunotherapy with vaccine-primed T-lymphocytes secondarily sensitized to tumor in vitro. (1993) (96)
- Intratumoral Expression of IL-17 and Its Prognostic Role in Gastric Adenocarcinoma Patients (2011) (95)
- Immunotherapy for cancer by direct gene transfer into tumors. (1994) (90)
- Reduction of toxicity of interleukin-2 and lymphokine-activated killer cells in humans by the administration of corticosteroids. (1987) (89)
- Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor. (1996) (88)
- Activation by anti-CD3 of tumor-draining lymph node cells for specific adoptive immunotherapy. (1991) (87)
- A prospective evaluation of delta‐9‐tetrahydrocannabinol as an antiemetic in patients receiving adriamycin and cytoxan chemotherapy (1981) (87)
- Comprehensive Axillary Evaluation in Neoadjuvant Chemotherapy Patients With Ultrasonography and Sentinel Lymph Node Biopsy (2005) (86)
- Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo. (2013) (85)
- Prospective evaluation of hepatic imaging studies in the detection of colorectal metastases: correlation with surgical findings. (1989) (85)
- Systemic administration of recombinant human interleukin-2 in mice. (1984) (83)
- Phase Ib Trial Assessing Autologous, Tumor-pulsed Dendritic Cells as a Vaccine Administered With or Without IL-2 in Patients With Metastatic Melanoma (2008) (82)
- Mammographic screening of TRAM flap breast reconstructions for detection of nonpalpable recurrent cancer. (2002) (81)
- Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells (2015) (81)
- Hepatic metastasis detection: comparison of three CT contrast enhancement methods. (1987) (80)
- Injection of complementary DNA encoding interleukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model. (1996) (80)
- Stimulation of tumor-draining lymph node cells with superantigenic staphylococcal toxins leads to the generation of tumor-specific effector T cells. (1994) (78)
- Cellular interactions in effector cell generation and tumor regression mediated by anti-CD3/interleukin 2-activated tumor-draining lymph node cells. (1992) (77)
- A phase I clinical trial utilizing autologous tumor-infiltrating lymphocytes in patients with primary hepatocellular carcinoma (2015) (75)
- Mutations in linker histone genes HIST 1 H 1 B , C , D , and E ; OCT 2 ( POU 2 F 2 ) ; IRF 8 ; and ARID 1 A underlying the pathogenesis of follicular lymphoma (2014) (75)
- Rate of Freeze Alters the Immunologic Response After Cryoablation of Breast Cancer (2010) (74)
- Intratumoral IL-12 and TNF-α–Loaded Microspheres Lead To Regression of Breast Cancer and Systemic Antitumor Immunity (2004) (73)
- Immunogenetic therapy of human melanoma utilizing autologous tumor cells transduced to secrete granulocyte-macrophage colony-stimulating factor. (2000) (72)
- Recombinant interleukin 12 enhances cellular immune responses to vaccination only after a period of suppression. (1998) (72)
- Adoptive immunotherapy of microscopic and advanced visceral metastases with in vitro sensitized lymphoid cells from mice bearing progressive tumors. (1988) (72)
- Antitumor effector B cells directly kill tumor cells via the Fas/FasL pathway and are regulated by IL‐10 (2015) (69)
- CXC Chemokine Ligand 13 and CC Chemokine Ligand 19 Cooperatively Render Resistance to Apoptosis in B Cell Lineage Acute and Chronic Lymphocytic Leukemia CD23+CD5+ B Cells1 (2006) (68)
- Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta. (2008) (68)
- Adoptive immunotherapy of breast cancer with lymph node cells primed by cryoablation of the primary tumor. (2006) (67)
- IL-17A Promotes Immune Cell Recruitment in Human Esophageal Cancers and the Infiltrating Dendritic Cells Represent a Positive Prognostic Marker for Patient Survival (2013) (67)
- Different cytokine profiles released by CD4+ and CD8+ tumor‐draining lymph node cells involved in mediating tumor regression (1997) (65)
- Regulatory Roles of miRNA in the Human Neural Stem Cell Transformation to Glioma Stem Cells (2014) (64)
- Interleukin-6 Inhibits Regulatory T Cells and Improves the Proliferation and Cytotoxic Activity of Cytokine-induced Killer Cells (2012) (64)
- Polarization effects of 4-1BB during CD28 costimulation in generating tumor-reactive T cells for cancer immunotherapy. (2003) (63)
- Preoperative radiation therapy and iododeoxyuridine for large retroperitoneal sarcomas. (1995) (62)
- Clinicopathologic Features Associated With Having Four or More Metastatic Axillary Nodes in Breast Cancer Patients With a Positive Sentinel Lymph Node (2006) (62)
- Generation of T-cells reactive to the poorly immunogenic B16-BL6 melanoma with efficacy in the treatment of spontaneous metastases. (1993) (62)
- Do Micromorphometric Features of Metastatic Deposits Within Sentinel Nodes Predict Nonsentinel Lymph Node Involvement in Melanoma? (2008) (60)
- Prognostic Significance of a Positive Nonsentinel Lymph Node in Cutaneous Melanoma (2009) (60)
- Dual-phase helical CT of nonfunctioning islet cell tumors. (1998) (60)
- Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type 1 pattern. (2005) (60)
- Detection of breast cancer in women after augmentation mammoplasty using fluorine-18-fluorodeoxyglucose-PET. (1994) (57)
- Liver metastases: detection with MR imaging at 0.5 and 1.5 T. (1989) (57)
- Hepatic artery chemotherapy for colorectal liver metastases: technical considerations and review of clinical trials. (2002) (55)
- Lymphatic Mapping and Sentinel Lymph Node Biopsy for Patients With Local Recurrence After Breast-Conservation Therapy (2006) (55)
- Therapeutic Efficacy of Cancer Stem Cell Vaccines in the Adjuvant Setting. (2016) (54)
- Mechanism of action of Cyclosporin A: inhibition of lymphokine secretion studied with antigen-stimulated T cell hybridomas. (1984) (54)
- Comparisons of dynamic infusion and delayed computed tomography, intraoperative ultrasound, and palpation in the diagnosis of liver metastases. (1993) (54)
- Differences in biodistribution of indium-111-and iodine-131-labeled B72.3 monoclonal antibodies in patients with colorectal cancer. (1989) (52)
- Computed tomography in staging of patients with melanoma metastatic to the regional nodes (1997) (51)
- Economic implications of hepatic arterial infusion chemotherapy in treatment of nonresectable colorectal liver metastases. Meta-Analysis Group in Cancer. (1997) (49)
- Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer. (2007) (49)
- Current status of adoptive immunotherapy of cancer. (1996) (48)
- Diverse manifestations of tumorigenicity and immunogenicity displayed by the poorly immunogenic B16-BL6 melanoma transduced with cytokine genes (1996) (48)
- Overview of interleukin-2 as an immunotherapeutic agent. (1989) (46)
- Synergistic effect of intratumoral IL-12 and TNF-alpha microspheres: systemic anti-tumor immunity is mediated by both CD8+ CTL and NK cells. (2007) (46)
- Selective incorporation of iododeoxyuridine into DNA of hepatic metastases versus normal human liver (1988) (44)
- Axillary Staging Prior to Neoadjuvant Chemotherapy for Breast Cancer: Predictors of Recurrence (2008) (44)
- Differences in the effects of host suppression on the adoptive immunotherapy of subcutaneous and visceral tumors. (1986) (42)
- Capecitabine and radiation therapy preceded and followed by combination chemotherapy in advanced pancreatic cancer. (2005) (42)
- Long-term Cultured Human Neural Stem Cells Undergo Spontaneous Transformation to Tumor-Initiating Cells (2011) (42)
- Direct Gene Transfer for Treatment of Human Cancer (1995) (40)
- Functional and psychosocial effects of multimodality limb-sparing therapy in patients with soft tissue sarcomas. (1989) (40)
- A phase I study of intraarterial iododeoxyuridine in patients with colorectal liver metastases. (1989) (39)
- The toxicity of recombinant human interleukin-2 in rats following intravenous infusion. (1987) (38)
- Mammographic appearance of recurrent breast carcinoma in six patients with TRAM flap breast reconstructions. (1998) (38)
- Significance of Multiple Lymphatic Basin Drainage in Truncal Melanoma Patients Undergoing Sentinel Lymph Node Biopsy (2006) (37)
- Intratumoral delivery of encapsulated IL-12, IL-18 and TNF-α in a model of metastatic breast cancer (2010) (37)
- Interferon-γ-inducing factor elicits antitumor immunity in association with interferon-γ production (1998) (37)
- Interleukin-12 cDNA skin transfection potentiates human papillomavirus E6 DNA vaccine-induced antitumor immune response (1999) (37)
- Therapeutic Effects of Tumor Reactive CD4+ Cells Generated From Tumor-Primed Lymph Nodes Using Anti-CD3/Anti-CD28 Monoclonal Antibodies (2002) (36)
- Interruption of the inferior vena cava for the prevention of recurrent pulmonary embolism. (1985) (35)
- Radiotherapy Combined With Intratumoral Dendritic Cell Vaccination Enhances the Therapeutic Efficacy of Adoptive T-cell Transfer (2009) (35)
- Simultaneous Targeting of CD3 on T Cells and CD40 on B or Dendritic Cells Augments the Antitumor Reactivity of Tumor-Primed Lymph Node Cells1 (2005) (35)
- Effects of Tumor Necrosis Factor-α on the In Vitro Maturation of Tumor-reactive Effector T Cells (2000) (34)
- Ex vivo culture with interleukin (IL)-12 improves CD8(+) T-cell adoptive immunotherapy for murine leukemia independent of IL-18 or IFN-gamma but requires perforin. (2006) (34)
- Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs. (2020) (34)
- The registry case finding engine: an automated tool to identify cancer cases from unstructured, free-text pathology reports and clinical notes. (2007) (34)
- Adoptive Transfer of CD8+ T Cells Generated from Induced Pluripotent Stem Cells Triggers Regressions of Large Tumors Along with Immunological Memory. (2016) (33)
- Unique characteristics associated with systemic adoptive immunotherapy of experimental intracerebral tumors. (1995) (33)
- Effects of Tumor Irradiation on Host T-Regulatory Cells and Systemic Immunity in the Context of Adoptive T-Cell Therapy in Mice (2013) (32)
- Adoptive immunotherapy of murine intracerebral tumors with anti-CD3/interleukin-2-activated tumor-draining lymph node cells. (1994) (32)
- Extent of Lumpectomy for Breast Cancer After Diagnosis by Stereotactic Core Versus Wire Localization Biopsy (1999) (31)
- Iododeoxyuridine (IdUrd) incorporation into DNA of human hematopoietic cells, normal liver and hepatic metastases in man: as a radiosensitizer and as a marker for cell kinetic studies. (1989) (31)
- Small bowel obstruction as a complication of disseminated varicella-zoster infection. (1978) (31)
- Cancer immunotherapy: current status and future directions. (2013) (31)
- A novel role for autologous tumour cell vaccination in the immunotherapy of the poorly immunogenic B16-BL6 melanoma. (1992) (30)
- Dual-phase helical CT of nonfunctioning islet cell tumors. (1998) (30)
- Adjuvant chemotherapy for treatment of extremity soft tissue sarcomas: Review of National Cancer Institute experience (1985) (30)
- Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma (2016) (29)
- Interleukin-21 augments the efficacy of T-cell therapy by eliciting concurrent cellular and humoral responses. (2008) (29)
- Intratumoral Dendritic Cells and Chemoradiation for the Treatment of Murine Squamous Cell Carcinoma (2008) (29)
- Development of antitumor reactivity in regional draining lymph nodes from tumor-immunized and tumor-bearing murine hosts. (1989) (29)
- CX3CR1-CD8+ T cells are critical in antitumor efficacy, but functionally suppressed in the tumor microenvironment. (2020) (29)
- Integrin β4-targeted cancer immunotherapies inhibit tumor growth and decrease metastasis. (2019) (29)
- Characterization of Bridging Integrator 1 (BIN1) as a Potential Tumor Suppressor and Prognostic Marker in Hepatocellular Carcinoma (2012) (29)
- Adoptive immunotherapy of cancer with activated lymph node cells primed in vivo with autologous tumor cells transduced with the GM-CSF gene. (1996) (29)
- Diagnostic procedures and pretreatment evaluation of soft tissue sarcomas. (1994) (28)
- Characteristics and in vivo homing of long-term T-cell lines and clones derived from tumor-draining lymph nodes. (1994) (28)
- Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy. (2020) (28)
- Cellular basis of immunologic interactions in adoptive T cell therapy of established metastases from a syngeneic murine sarcoma. (1988) (28)
- Enhanced adjuvant effect of granulocyte-macrophage colony-stimulating factor plus interleukin-12 compared with either alone in vaccine-induced tumor immunity (1999) (28)
- Cancer Stem Cell Vaccination With PD-L1 and CTLA-4 Blockades Enhances the Eradication of Melanoma Stem Cells in a Mouse Tumor Model (2018) (28)
- Dendritic cell-based vaccines in the setting of peripheral blood stem cell transplantation: CD34+ cell-depleted mobilized peripheral blood can serve as a source of potent dendritic cells. (1998) (27)
- Preoperative idoxuridine and radiation for large soft tissue sarcomas: Clinical results with five-year follow-up (1998) (27)
- Donor Cell Cycling, Trafficking, and Accumulation during Adoptive Immunotherapy for Murine Lung Metastases (2004) (27)
- Radiation-induced apoptosis along with local and systemic cytokine elaboration is associated with DC plus radiotherapy-mediated renal cell tumor regression. (2007) (27)
- Sentinel Lymph Node Biopsy Use Among Melanoma Patients 75 Years of Age and Older (2015) (27)
- A Nomogram for Predicting the Benefit of Adjuvant Cytokine-Induced Killer Cell Immunotherapy in Patients with Hepatocellular Carcinoma (2015) (27)
- Tumor-specific granulocyte/macrophage colony-stimulating factor and interferon γ secretion is associated with in vivo therapeutic efficacy of activated tumor-draining lymph node cells (1995) (26)
- Does the Method of Biopsy Affect the Incidence of Sentinel Lymph Node Metastases? (2006) (25)
- Generation of Therapeutic T‐Lymphocytes After In Vivo Tumor Transfection with an Allogeneic Class I Major Histocompatibility Complex Gene (1995) (25)
- Immunotherapy with sensitized lymphocytes. (1992) (25)
- Multidisciplinary cancer clinics: Their time has come (1998) (25)
- Reduced efficacy of allogeneic versus syngeneic fibroblasts modified to secrete cytokines as a tumor vaccine adjuvant. (1997) (24)
- Suppressive effects of visceral tumor on the generation of antitumor T cells for adoptive immunotherapy. (1991) (24)
- Is Blue Dye Indicated for Sentinel Lymph Node Biopsy in Breast Cancer Patients With a Positive Lymphoscintigram? (2005) (24)
- IL-2 augments the therapeutic efficacy of adoptively transferred B cells which directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways (2016) (23)
- Enhancement of Immune Reactivity in the Lymph Nodes Draining a Murine Melanoma Engineered to Elaborate Interleukin‐4 (1994) (23)
- Biopsy techniques for skin, soft-tissue, and bone neoplasms. (1995) (23)
- Antitumor Reactivity of Anti-CD3/Anti-CD28 Bead-Activated Lymphoid Cells: Implications for Cell Therapy in a Murine Model (2003) (23)
- Is mammography useful in screening for local recurrences in patients with TRAM flap breast reconstruction after mastectomy for multifocal DCIS? (1998) (23)
- Immune responsiveness to a murine mammary carcinoma modified to express B7-1, interleukin-12, or GM-CSF. (1997) (23)
- Direct Gene Transfer for the Understanding and Treatment of Human Disease (1994) (22)
- Targeting cancer stem cells via dendritic-cell vaccination (2012) (22)
- B lymphocytes as effector cells in the immunotherapy of cancer (2012) (22)
- Transdifferentiation-Induced Neural Stem Cells Promote Recovery of Middle Cerebral Artery Stroke Rats (2015) (21)
- Preferential homing of passively transferred T cells into skin allografts of mice. (1979) (21)
- Follicular lymphoma–associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR (2019) (21)
- Resection of liver tumors: technical aspects. (2002) (21)
- 4-1BB Costimulation of Effector T Cells for Adoptive Immunotherapy of Cancer: Involvement of Bcl Gene Family Members (2007) (20)
- Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells (2014) (19)
- Iliac arterial-enteric fistulas occurring after pelvic irradiation. (1987) (19)
- Tumor immunology. (1997) (18)
- Clinical implications of the new biology in the development of melanoma vaccines (1999) (18)
- COMPARISON OF COMPUTED AND CONVENTIONAL WHOLE LUNG TOMOGRAPHY IN THE DETECTION OF PULMONARY METASTASES (1977) (18)
- Toxicity of recombinant human interleukin-2 in rats following intravenous infusion. (1985) (17)
- Intratumoral microdistribution of [131I]MB-1 in patients with B-cell lymphoma following radioimmunotherapy. (1997) (17)
- CCL19 and CXCL13 Synergistically Regulate Interaction between B Cell Acute Lymphocytic Leukemia CD23+CD5+ B Cells and CD8+ T Cells1 (2007) (17)
- Tumor-induced suppression of antitumor reactivity and depression of TCRzeta expression in tumor-draining lymph node lymphocytes: possible relationship to the Th2 pathway. (1997) (17)
- Immediate transverse rectus abdominis musculocutaneous flap reconstruction after mastectomy. (1995) (17)
- FOXP 3 Defines Regulatory T Cells in Human Tumor and Autoimmune Disease (2009) (17)
- Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer (2007) (17)
- Hepatic perfusion during hepatic artery infusion chemotherapy: evaluation with perfusion CT and perfusion scintigraphy. (1989) (17)
- Phenotype analyses and cellular mechanisms of the pre-effector T-lymphocyte response to a progressive syngeneic murine sarcoma. (1990) (16)
- Tumor-Specific Responses in Lymph Nodes Draining Murine Sarcomas Are Concentrated in Cells Expressing P-Selectin Binding Sites1 (2001) (16)
- Antitumor Reactivity of Lymph Node Cells Primed In Vivo With Dendritic Cell-Based Vaccines (2001) (16)
- Dendritic cells pulsed with keyhole limpet hemocyanin and cryopreserved maintain anti-tumor activity in a murine melanoma model. (2008) (16)
- Effector phenotype and immunologic specificity of T-cell-mediated adoptive therapy for a murine tumor that lacks intrinsic immunogenicity. (1990) (16)
- Validation of Statistical Predictive Models Meant to Select Melanoma Patients for Sentinel Lymph Node Biopsy (2011) (15)
- Uncovered skin grafts in mice. (1979) (15)
- Surgery: Basic science and clinical evidence: Second edition (2008) (15)
- Reprogramming of Melanoma Tumor-Infiltrating Lymphocytes to Induced Pluripotent Stem Cells (2015) (15)
- Genetic approaches to adoptive cellular therapy of malignancy. (1996) (15)
- Cross-reactivity of anti-CD3/IL-2 activated effector cells derived from lymph nodes draining heterologous clones of a murine tumor. (1993) (15)
- Principles of Surgical Therapy in Oncology (2006) (14)
- A Phase II Trial of Interleukin‐2 and Interferon‐α in the Treatment of Metastatic Colorectal Carcinoma (1995) (14)
- Gene gun application in the generation of effector T cells for adoptive immunotherapy (2000) (14)
- Antitumor Activity of T Cells Generated from Lymph Nodes Draining the SEA-expressing Murine B16 Melanoma and Secondarily Activated with Dendritic Cells (2006) (14)
- Assessment of Cognitive Impairment and Complaints in Individuals With Colorectal Cancer. (2016) (14)
- Comparison of attenuation-corrected and non-corrected FDG-PET images for axillary nodal staging in newly diagnosed breast cancer. (2002) (13)
- Economic implications of hepatic arterial infusion versus intravenous chemotherapy or symptom palliation in the treatment of nonresectable colorectal liver metastases. Meta-Analysis Group In Cancer. (1999) (13)
- Gemcitabine-based combination chemotherapy followed by radiation with capecitabine as adjuvant therapy for resected pancreas cancer. (2009) (13)
- Systemic administration of recombinant interleukin-2 in mice (1984) (13)
- Characterization of a Novel Transgenic Mouse Tumor Model for Targeting HER2+ Cancer Stem Cells (2013) (12)
- Activation of T lymphocytes for the adoptive immunotherapy of cancer (1994) (12)
- ASSESSMENT OF T CELL FUNCTION WITH A SKIN ALLOGRAFT ASSAY (1980) (12)
- Concurrent induction of CD4+ and CD8+ T cells during tumor growth with antitumor reactivity in adoptive immunotherapy. (1997) (12)
- Interferon-gamma-inducing factor elicits antitumor immunity in association with interferon-gamma production. (1998) (12)
- Cytokines as an adjuvant to tumor vaccines: Efficacy of local methods of delivery (1997) (11)
- Targeted Gene Transfer for Adenocarcinoma Using a Combination of Tumor‐specific Antibody and Tissue‐specific Promoter (1998) (11)
- 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two (2016) (11)
- CD95-Mediated Tumor Recognition by CD4+ Effector Cells in a Murine Mammary Model (2000) (11)
- Direct transfer of a foreign MHC gene into human melanoma alters T cell receptor Vβ usage by tumor-infiltrating lymphocytes (1996) (11)
- In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models (2021) (11)
- Dendritic‐cell‐based immunotherapy evokes potent anti‐tumor immune responses in CD105+ human renal cancer stem cells (2017) (10)
- National Cancer Institute Experience in the Management of High-Grade Extremity Soft Tissue Sarcomas (1988) (10)
- EXPRESSION OF CANCER TESTIS ANTIGENS IN HUMAN BRCA-ASSOCIATED BREAST CANCERS-POTENTIAL TARGETS FOR IMMUNOPREVENTION? (2010) (10)
- Chimeric Antigen Receptor-modified Donor Lymphocyte Infusion Improves the Survival of Acute Lymphoblastic Leukemia Patients With Relapsed Diseases After Allogeneic Hematopoietic Stem Cell Transplantation (2019) (10)
- In vivo antitumor efficacy of tumor-draining lymph node cells activated with nonspecific T-cell reagents. (1993) (10)
- Enhancing Effect of Interleukin 1α Administration on Antitumor Effector T-Cell Development (1991) (10)
- In search of an effective antiemetic: a nusring staff participates in marijuana research. (1980) (10)
- The role of fine-needle aspiration and pneumocystography in the treatment of impalpable breast cysts. (1992) (10)
- Generation of a Tumor-specific Systemic Response After Intratumoral Injection of IL-12 and IL-18–loaded Polylactic Acid Microspheres (2007) (10)
- Effects of tumor necrosis factor-alpha on the in vitro maturation of tumor-reactive effector T cells. (2000) (10)
- Development and Application of Cancer Stem Cell-Targeted Vaccine in Cancer Immunotherapy (2017) (9)
- Promise of cancer stem cell vaccine (2015) (9)
- Immunologic Targeting of Cancer Stem Cells. (2019) (8)
- Mastectomy and concomitant sentinel lymph node biopsy for invasive breast cancer. (2004) (8)
- Abstract 4840: Blockade of IL-10 production in effector B cells significantly increases their therapeutic efficacy in cancer adoptive immunotherapy (2012) (7)
- Adoptive cellular therapy of malignancy. (1993) (7)
- Distinct immunologic specificity of tumor regression mediated by effector cells isolated from immunized and tumor-bearing mice. (1989) (7)
- Basic principles associated with gene therapy of cancer. (1995) (7)
- Enhanced antitumor reactivity of tumor-sensitized T cells by interferon alfa. (1991) (6)
- Immunobiologic effects of cytokine gene transfer of the B16-BL6 melanoma. (1993) (6)
- Axillary Pathologic Complete Response in Inflammatory Breast Cancer Patients: Implications for SLNB? (2019) (6)
- Molecular genetic interventions for cancer. (1994) (6)
- Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells (2022) (6)
- Targeting cancer stem cells via integrin β4 (2021) (5)
- Response: Endogenous IL-17, tumor growth, and metastasis (2010) (5)
- Secretion of Both IL‐2 and IL‐4 by Tumor Cells Results in Rejection and Immunity (1996) (5)
- A phase II trial of interleukin-2 and interferon-alpha in the treatment of metastatic colorectal carcinoma. (1995) (4)
- Hepatic Arterial Infusion Chemotherapy: Clinical Trials with the Implantable Pump (1987) (4)
- Applications of gene transfer to cellular immunotherapy. (2002) (4)
- Strategies of lymphocyte activation for the adoptive immunotherapy of metastatic cancer: a review. (1993) (4)
- The elderly breast cancer patient: Association of age, tumor size, and grade with sentinel lymph node status. (2012) (3)
- Intratumoral Dendritic Cell Administration Radiotherapy Potentiates the Therapeutic Efficacy of Updated (2003) (3)
- Hepatoma registry of the Western world. Repeat Hepatic Resection Registry. (1994) (3)
- Essential Practice of Surgery (2003) (3)
- Use of gene gun for genetic immunotherapy : in vitro and in vivo methods. (2001) (3)
- OK‐432 synergizes with IFN‐γ to confer dendritic cells with enhanced antitumor immunity (2014) (3)
- Tumor and Stem Cell Biology Cancer Stem Cell Vaccination Confers Signi fi cant Antitumor Immunity (2012) (3)
- Immune Escape: Immunosuppressive Networks (2007) (3)
- HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells. (2021) (3)
- Delta-9-Tetrahydrocannabinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate (2020) (3)
- A large scale method of separating multiple lymphokines secreted by the murine EL-4 thymoma. (1985) (3)
- Emerging concepts regarding pro- and anti tumor properties of B cells in tumor immunity (2022) (3)
- Divergent effects of TNFα in the adoptive immunotherapy of a murine sarcoma (1992) (3)
- Applications of Gene Transfer in the Adoptive Immunotherapy of Cancer (2002) (3)
- Efficient transduction of early passage human melanoma to secrete IL-4. (1995) (2)
- IRX-2 therapy with PD-L1 blockade in immunocompetent animal model. (2019) (2)
- Perspectives on interleukin-2 immunotherapy for colon cancer. (1994) (2)
- Immunotherapy Generating Tumor-reactive T Cells for Cancer Polarization Effects of 4-1 BB during CD 28 Costimulation in Updated Version (2003) (2)
- Immunolymphoscintigraphy in breast cancer: evaluation using 131I-labeled monoclonal antibody B72.3. (1998) (2)
- Comprar Surgery · Basic Science and Clinical Evidence | Norton, Jeffrey A. | 9780387308005 | Springer (2008) (2)
- Limb-Sparing Surgery for Extremity Soft Tissue Sarcomas: Functional and Rehabilitation Considerations (1993) (2)
- Effect of interleukin-1 alpha on the in vitro activation of tumor-draining lymph node cells for adoptive immunotherapy. (1994) (2)
- OP8. Economic implications of hepatic arterial infusion chemotherapy in the treatment of nonresectable colorectal liver metastases (1997) (2)
- Enhancing effect of interleukin 1 alpha administration on antitumor effector T-cell development. (1991) (2)
- Abstract 3220: Enhancing breast cancer immunotherapy via IONP-mediated photothermal therapy (2019) (2)
- Abrogation of T cell homing by alloantibody: A new mechanism of immunological enhancement (1980) (2)
- ENHANCING ALLOANTIBODY EFFECTIVE DURING SENSITIZATION BUT NOT EFFECTOR PHASE OF SKIN GRAFT REJECTION (1979) (2)
- Do older patients with T1a lesions require sentinel lymph node biopsy (2010) (2)
- Recurrent STAT6 Mutations In Follicular Lymphoma (2013) (1)
- From the guest editors: introduction to local therapies in the treatment of liver cancer. (2010) (1)
- Cancer stem cell antigen nanodisc cocktail elicits anti-tumor immune responses in melanoma. (2022) (1)
- Genetic approaches to adoptive cellular immunotherapy. (1998) (1)
- Impact of Breast Cancer Pretreatment Nodal Burden and Disease Subtype on Axillary Surgical Management. (2021) (1)
- Differential activity of interferon-alpha on the function of sensitized T cells in adoptive immunotherapy (1990) (1)
- B Cells in Cancer Immunology: For or Against Cancer Growth? (2015) (1)
- Immunity Cancer Stem Cell Vaccination Confers Significant Antitumor (2012) (1)
- Abstract 4796: Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells (2014) (1)
- CCL19 and CXCL13 synergistically regulate interaction between B cell acute lymphocytic leukemia CD23+CD25+ B cells and CD8 + T cells (Journal of Immunology (2007) 179, (2880-2888)) (2007) (1)
- Liver metastasis of a human colorectal cancer containing two actively growing subclones. (1998) (1)
- Melanoma and human leukocyte antigen status: The missing link? (2002) (1)
- THIS ARTICLE HAS BEEN RETRACTED Essential Role of Sphingosine‐1‐Phosphate Receptor 1‐Bearing CD8+CD44+CCR7+ T Cells in Acute Skin Allograft Rejection (2008) (1)
- MetabolicImagingof Human Extremity MusculoskeletalTumors by PET (1988) (1)
- Analysis of the Coding Genome of Follicular Lymphoma Identifies Multiple Novel Recurrently Mutated Genes (2012) (1)
- Abstract 487: Effector B cells in cancer adoptive immunotherapy. (2013) (1)
- The Dawn of a New Age in Cancer Immunotherapy. (2019) (1)
- Integrin b4–Targeted Cancer Immunotherapies Inhibit Tumor Growth and Decrease Metastasis A C (2020) (0)
- Abstract 375: Integrin β4-targeted cancer immunotherapies (2019) (0)
- Abstract 1676: Involvement of B cells in the efficacy of anti-PD-L1 antibodies: Suppression of B cells by cancer stem cells (2018) (0)
- Vaccine Therapy for Patients With Melanoma (2017) (0)
- Abstract 1410: Evaluation of the immunogenicity of ALDHhighhuman head and neck squamous cell carcinoma cancer stem cellsin vitro (2015) (0)
- 1140 Cancer stem cells and PD-L1-expresing exosomes suppress anti-tumor effector B cells (2022) (0)
- Abstract 540: Adjuvant effect of anti-PD-L1 in boosting HER2-targeted T cell adoptive immunotherapy (2016) (0)
- Abstract 749: Cancer stem cell vaccination confers significant anti-tumor immunity by selectively targeting cancer stem cells (2011) (0)
- Analysis of 54 Follicular Lymphomas By Whole Exome Sequencing Identifies Multiple Novel Recurrently Mutated Pathways (2015) (0)
- Title Reprogramming of Melanoma Tumor-Infiltrating Lymphocytes to Induced Pluripotent Stem Cells (2016) (0)
- Adoptively transferred B cells directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways (2017) (0)
- Effects of Tumor Necrosis Factor-&agr; on the In Vitro Maturation of Tumor-Reactive Effector T Cells (2000) (0)
- Abstract 2256: Cancer stem cells and exosomal PD-L1 suppress anti-tumor B cells (2023) (0)
- Abstract 1340: Antitumor effector B cells directly kill tumor cells involving the CXCL12/CXCR4 pathway and their therapeutic efficacy is enhanced by IL-2 (2015) (0)
- Divergent effects of TNF alpha in the adoptive immunotherapy of a murine sarcoma. (1992) (0)
- Specific adoptive immunotherapy: Characterization of lymphoid subpopulations involved in tumor rejection (1986) (0)
- Abstract 1358: Generation of induced pluripotent stem cells from tumor-infiltrating lymphocytes (2015) (0)
- Gene Therapy in the Treatment of Cancer: Genetically modified tumor cells as tumor vaccines (1998) (0)
- Role of regional lymph nodes in the development of tumor immunity (1987) (0)
- Lymphocytic Leukemia CD23+CD5+ B Cells Interaction between B Cell Acute CCL19 and CXCL13 Synergistically Regulate (2013) (0)
- Abstract LB-297: HER2-targeted antibody drug conjugates induce host immunity and target cancer stem cells and the efficacy can be enhanced by anti-PD-L1 (2018) (0)
- Abstract 1938: Superiority of B plus T cell therapy in a spontaneous pulmonary metastasis model (2010) (0)
- Acute toxicity of recombinant interleukin-2 in rodents (1985) (0)
- Abrogation of T cell homing by alloantibody. (1980) (0)
- P-selectin ligand provides a surrogate marker for tumor-reactive cells in TDLN (2003) (0)
- the Antitumor Reactivity of Tumor-Primed and CD40 on B or Dendritic Cells Augments Simultaneous Targeting of CD3 on T Cells (2005) (0)
- B-Cells in Cancer Immunology: For or Against Cancer Growth? (2020) (0)
- Abstract 3322: Protective antitumor immunity induced by ALDEFLUOR+ enriched cancer stem cells (2010) (0)
- Abstract 3329: Increasing the efficacy of cancer stem cell-based vaccine in the PD-L1/PD-1 blockade (2016) (0)
- Cancer stem cell (CSC) vaccination induces anti-csc immunity by priming csc-reactive antibodies and cytotoxic t lymphocytes (2012) (0)
- Tumor Microenvironment Dynamics and the Regulation by IL-2 in the Cutting Edge: Th17 and Regulatory T Cell (2007) (0)
- Staging of patients with suspected isolated colorectal liver metastases. (1987) (0)
- Acute Abdomen, Bowel Obstruction, and Fistula (2020) (0)
- Ia+ cell participiation in specific adoptive immunotherapy (1987) (0)
- Extremity mass (Sarcoma) (2012) (0)
- Abstract 2157: Generation of Rab27ako and PD-L1ko tumor cells to evaluate potential suppression of exosomal PD-L1 on host immune components involved in cancer immunotherapy (2020) (0)
- Surgeon Fatigue Does not Affect Morbidity or Mortality After Esophagectomy (2013) (0)
- Abstract 2046: Potential suppression of B effector cells by exosomal PD-L1 on anti-cancer stem cell immunity (2022) (0)
- Introduction to local therapies in the treatment of liver cancer (2012) (0)
- Second Hepatic Resections in Patients with Liver Metastases from Colorectal Carcinoma (1990) (0)
- Acute Abdomen, Bowel/Biliary Obstruction, and Fistula (2014) (0)
- PP-2-408 Tumor-reactive precursors in TDLN : T cells expressing P-selectin ligands (2002) (0)
- Correction: Delta-9-Tetrahydrocannabinol as an Antiemetic in Methotrexate Treatment (1985) (0)
- Abstract 1530: Therapeutic efficacy of cancer stem cell vaccine in an adjuvant setting (2013) (0)
- Advanced renal cell carcinoma (2000) (0)
- Abstract 514: Specific anti-HER2 host immunity conferred by HER2-targeted antibody drug conjugate therapy and checkpoint blockade (2021) (0)
- Erratum: Essential role of sphingosine-1-phosphate receptor 1-bearing CD8+CD44+CCR7+ T cells in acute skin allograft rejection (American Journal of Transplantation (2008) 8 (1401-1412) DOI:10.1111/j.1600-6143.2008.02275.x) (2011) (0)
- Treating Colon Cancer With a Melanoma Vaccine? Preposterous? (2001) (0)
- Correction: Delta-9-Tetrahydrocannabinol in Experimental Cigarettes (1985) (0)
- Enzyme Assay for Fucosyltransferase-VII and Fucosyltransferase-IV (2002) (0)
- T Cell Therapy of Patients with Advanced Renal Cell Carcinoma (1995) (0)
- Safety a n d Toxicity o f Catheter G e n e Delivery to the P u l m o n a r y Vasculature in a Patient with Metastatic (2009) (0)
- Adoptive immunotherapy and therapeutic concurrent chemoradiation have synergistic antitumor effects in a mouse model of squamous cell carcinoma (2008) (0)
- Erratum: Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression (Cancer Research (December 1, 2001) (8513-8519)) (2002) (0)
- Abstract 1621: Adoptively transferred B cells directly kill tumor cells via the CXCR4/CXCL12 & perforin pathways (2017) (0)
- Cytokine Therapy of Patients with Cancer (1989) (0)
- EDITORIAL Improving Surgical Outcomes for Cancer in the United States (2007) (0)
- Abstract 3803: Synergistic inhibition of thioridazine combined with carboplatin on triple negative breast cancer by targeting cancer stem cells (2020) (0)
- Immunologic Approaches to Targeting Cancer Stem Cells (2015) (0)
- Axillary staging for breast cancer in the octogenarian population (2008) (0)
- Commentary (2001) (0)
- Vaccine-Primed Lymph Node Cells in the Adoptive Immunotherapy of Cancer: Presence of Host Immune Suppression Induced by Established Cancer (2009) (0)
- GUEST EDITORIAL Multidisciplinary Cancer Clinics: Their Time Has Come (1998) (0)
- Immunotherapy for Solid Malignancies (2019) (0)
- IL-10 blockade increases the therapeutic efficacy of effector B cells in cancer adoptive immunotherapy by modulating host cellular and humoral antitumor immunity (2013) (0)
- Sentinel lymph node biopsy among elderly patients with melanoma. (2014) (0)
- Functional Analyses of V-Atpase Mutations in Follicular Lymphoma (2016) (0)
- Abstract 4981: HER2-targeted antibody drug conjugates (ADCs) induce host immunity against cancer stem cells and are enhanced by anti-PD-L1 (2019) (0)
- Adjuvant effects of anti-4-1BB monoclonal antibody administration in adoptive T cell therapy of cancer involve host NK cells and the Stat 4 signaling pathway (2006) (0)
- Intralesional IL-12 and TNF-α loaded microspheres can generate systemic anti-tumor immunity to B16 melanoma (2004) (0)
- Development of Adoptive Immunotherapy with In Vitro Sensitized T Lymphocytes From Mice Bearing Progressively Growing Tumors (2018) (0)
- OP046: Targeting cancer stem cells (CSC) in oral cavity head and neck squamous cell carcinoma (HNSCC) with dendritic cell (DC) vaccines (2013) (0)
- Draining Murine Sarcomas Are Tumor-Specific Responses in Lymph Nodes (2001) (0)
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What Schools Are Affiliated With Alfred E. Chang?
Alfred E. Chang is affiliated with the following schools:
