Alfredo Arrigo Sadun
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Alfredo Arrigo Sadun's Degrees
- Masters Medicine University of California, San Francisco
- PhD Biophysics University of California, Berkeley
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(Suggest an Edit or Addition)Alfredo Arrigo Sadun's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mitochondrial dysfunction as a cause of optic neuropathies (2004) (721)
- Optic-nerve degeneration in Alzheimer's disease. (1986) (637)
- Optic nerve decompression surgery for nonarteritic anterior ischemic optic neuropathy (NAION) is not effective and may be harmful. The Ischemic Optic Neuropathy Decompression Trial Research Group. (1995) (376)
- Treatment of unresectable meningiomas with the antiprogesterone agent mifepristone. (1991) (363)
- Clinical expression of Leber hereditary optic neuropathy is affected by the mitochondrial DNA-haplogroup background. (2007) (344)
- Optic nerve damage in Alzheimer's disease. (1990) (327)
- Melanopsin retinal ganglion cell loss in Alzheimer disease (2015) (283)
- Retinal ganglion cell degeneration in Alzheimer's disease (1989) (266)
- Optic nerve degeneration and mitochondrial dysfunction: genetic and acquired optic neuropathies (2002) (265)
- Efficient mitochondrial biogenesis drives incomplete penetrance in Leber’s hereditary optic neuropathy (2013) (233)
- Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy. (2011) (228)
- Leber's hereditary optic neuropathy differentially affects smaller axons in the optic nerve. (2000) (223)
- Assessment of visual impairment in patients with Alzheimer's disease. (1987) (220)
- Idebenone treatment in Leber's hereditary optic neuropathy. (2011) (210)
- Mouse mtDNA mutant model of Leber hereditary optic neuropathy (2012) (196)
- Correlation between retinal nerve fibre layer thickness and optic nerve head size: an optical coherence tomography study (2005) (195)
- Haplogroup effects and recombination of mitochondrial DNA: novel clues from the analysis of Leber hereditary optic neuropathy pedigrees. (2006) (187)
- Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies. (2010) (178)
- Pilot study of optical coherence tomography measurement of retinal blood flow in retinal and optic nerve diseases. (2011) (174)
- Long-Term Administration of Mifepristone (RU486): Clinical Tolerance During Extended Treatment of Meningioma (2006) (168)
- Optical Coherence Tomography in Alzheimer’s Disease: A Meta-Analysis (2015) (165)
- Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders. (2009) (165)
- Effect of EPI-743 on the clinical course of the mitochondrial disease Leber hereditary optic neuropathy. (2012) (161)
- Extensive investigation of a large Brazilian pedigree of 11778/haplogroup J Leber hereditary optic neuropathy. (2003) (152)
- Detection and quantification of retinal nerve fiber layer thickness in optic disc edema using stratus OCT. (2006) (150)
- Vitreomacular adhesion in active and end-stage age-related macular degeneration. (2009) (146)
- Visual system involvement in patients with Friedreich's ataxia. (2009) (140)
- International Consensus Statement on the Clinical and Therapeutic Management of Leber Hereditary Optic Neuropathy (2017) (128)
- Acquired mitochondrial impairment as a cause of optic nerve disease. (1998) (127)
- Ocular changes in TgF344-AD rat model of Alzheimer's disease. (2014) (125)
- Macular holes and macular pucker: the role of vitreoschisis as imaged by optical coherence tomography/scanning laser ophthalmoscopy. (2007) (124)
- Leber's hereditary optic neuropathy with childhood onset. (2006) (123)
- Vitreoschisis in macular diseases (2010) (120)
- Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy (2008) (117)
- Morphometric comparisons of optic nerve axon loss in acquired immunodeficiency syndrome. (1992) (107)
- Age-related decline of human optic nerve axon populations (2006) (107)
- Mathematically modeling the involvement of axons in Leber's hereditary optic neuropathy. (2012) (105)
- Cigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways (2015) (103)
- Natural history of Leber's hereditary optic neuropathy: longitudinal analysis of the retinal nerve fiber layer by optical coherence tomography. (2010) (103)
- Leber’s Hereditary Optic Neuropathy (2011) (101)
- TNF-α-Induced Optic Nerve Degeneration and Nuclear Factor-κB p65 (2006) (100)
- Perioperative risk factors for posterior ischemic optic neuropathy. (2002) (99)
- Visual dysfunction without retinitis in patients with acquired immunodeficiency syndrome. (1992) (99)
- VITRECTOMY FOR FLOATERS: Prospective Efficacy Analyses and Retrospective Safety Profile (2014) (96)
- Apoptotic photoreceptor cell death after traumatic retinal detachment in humans. (1996) (95)
- Linezolid-induced optic neuropathy: a mitochondrial disorder? (2006) (93)
- Drug-Related Mitochondrial Optic Neuropathies (2013) (92)
- Optical coherence tomography can measure axonal loss in patients with ethambutol-induced optic neuropathy (2005) (92)
- Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy (2020) (92)
- Microcystic macular degeneration from optic neuropathy: not inflammatory, not trans-synaptic degeneration. (2013) (90)
- Epidemic optic neuropathy in Cuba. Eye findings. (1994) (90)
- Ophthalmologic findings in a large pedigree of 11778/Haplogroup J Leber hereditary optic neuropathy. (2004) (89)
- α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging. (2011) (86)
- Retinal nerve fiber layer thickness in nonarteritic anterior ischemic optic neuropathy: OCT characterization of the acute and resolving phases (2008) (84)
- Association of optic disc size with development and prognosis of Leber's hereditary optic neuropathy. (2009) (83)
- Interleukin-6 in retinal ischemia reperfusion injury in rats. (2003) (82)
- Retinal Ganglion Cells and Circadian Rhythms in Alzheimer’s Disease, Parkinson’s Disease, and Beyond (2017) (78)
- The pupil light reflex in Leber's hereditary optic neuropathy: evidence for preservation of melanopsin-expressing retinal ganglion cells. (2013) (78)
- Metabolic optic neuropathies (2002) (77)
- Patterns of ganglion cell complex and nerve fiber layer loss in nonarteritic ischemic optic neuropathy by Fourier-domain optical coherence tomography. (2012) (77)
- SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF THE OPTIC DISK IN OPTIC NEUROPATHY. (2016) (77)
- Melanopsin-expressing retinal ganglion cells: implications for human diseases (2011) (75)
- Subclinical carriers and conversions in Leber hereditary optic neuropathy: a prospective psychophysical study. (2006) (75)
- Mitochondrial optic neuropathies (2002) (74)
- Optic neuropathies: the tip of the neurodegeneration iceberg (2017) (72)
- A case report of Wyburn-Mason syndrome and review of the literature (2007) (70)
- Retinal nerve fiber layer thickness in dominant optic atrophy measurements by optical coherence tomography and correlation with age. (2011) (69)
- Risk factors for ethambutol optic toxicity (2010) (69)
- Macular nerve fibre and ganglion cell layer changes in acute Leber's hereditary optic neuropathy (2015) (68)
- TNF-alpha-induced optic nerve degeneration and nuclear factor-kappaB p65. (2006) (67)
- Ethambutol-induced vacuolar changes and neuronal loss in rat retinal cell culture: mediation by endogenous zinc. (2000) (66)
- Targeting estrogen receptor β as preventive therapeutic strategy for Leber's hereditary optic neuropathy. (2015) (65)
- Vision function in HIV-infected individuals without retinitis: report of the Studies of Ocular Complications of AIDS Research Group. (2008) (65)
- VITREO-PAPILLARY ADHESION IN MACULAR HOLE AND MACULAR PUCKER (2009) (64)
- Male prevalence of acquired color vision defects in asymptomatic carriers of Leber's hereditary optic neuropathy. (2007) (63)
- Clinical experiences in the management of traumatic optic neuropathy (1996) (62)
- Optical Coherence Tomography Angiography of the Optic Disc; an Overview (2017) (61)
- Ultrasound-based quantification of vitreous floaters correlates with contrast sensitivity and quality of life. (2015) (61)
- OPA1 mutations associated with dominant optic atrophy influence optic nerve head size. (2010) (61)
- A histopathologic and morphometric differentiation of nerves in optic nerve hypoplasia and Leber hereditary optic neuropathy. (1998) (59)
- Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset. (2021) (58)
- The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. (1998) (58)
- Ethambutol Optic Neuropathy: How We Can Prevent 100,000 New Cases of Blindness Each Year (2008) (56)
- Optic neuropathy associated with cryptococcal arachnoiditis in AIDS patients. (1989) (55)
- Optic nerve hypoplasia and maternal diabetes mellitus. (1986) (55)
- Accuracy of Diagnostic Imaging Modalities for Classifying Pediatric Eyes as Papilledema Versus Pseudopapilledema. (2017) (55)
- Update on ethambutol optic neuropathy (2006) (55)
- Optical coherence tomography angiography in acute arteritic and non-arteritic anterior ischemic optic neuropathy (2017) (54)
- Medical Management of Hereditary Optic Neuropathies (2014) (54)
- Early macular retinal ganglion cell loss in dominant optic atrophy: genotype-phenotype correlation. (2014) (54)
- A very large Brazilian pedigree with 11778 Leber's hereditary optic neuropathy. (2002) (54)
- Vitreopapillary adhesion in macular diseases. (2009) (53)
- Natural History of Conversion of Leber's Hereditary Optic Neuropathy: A Prospective Case Series. (2017) (52)
- Chromatic and luminance contrast sensitivities in asymptomatic carriers from a large Brazilian pedigree of 11778 Leber hereditary optic neuropathy. (2005) (51)
- The human accessory optic system (1988) (51)
- MULTIFOCAL RETINAL CONTRACTION IN MACULAR PUCKER ANALYZED BY COMBINED OPTICAL COHERENCE TOMOGRAPHY/SCANNING LASER OPHTHALMOSCOPY (2008) (50)
- Parsing the differences in affected with LHON: genetic versus environmental triggers of disease conversion. (2016) (50)
- Accuracy of funduscopy to identify true edema versus pseudoedema of the optic disc. (2012) (47)
- Ophthalmologic and systemic features in möbius syndrome an italian case series. (2011) (47)
- Visual loss caused by rapidly progressive intracranial meningiomas during pregnancy. (1990) (46)
- AIDS-related optic neuropathy: a histological, virological and ultrastructural study (1995) (46)
- The Retina in Alzheimer's Disease: Histomorphometric Analysis of an Ophthalmologic Biomarker (2019) (45)
- Silent brain lesions in patients with isolated idiopathic optic neuritis (1987) (45)
- Peripapillary vessel density changes in Leber's hereditary optic neuropathy: a new biomarker (2018) (44)
- Histopathological and ultrastructural examination of optic nerve sheath decompression. (1995) (44)
- Mitochondrial optic neuropathies: our travels from bench to bedside and back again (2013) (43)
- Topographic Macular Microvascular Changes and Correlation With Visual Loss in Chronic Leber Hereditary Optic Neuropathy. (2018) (42)
- Mitochondrial dysfunction in optic neuropathies: animal models and therapeutic options. (2013) (41)
- Retinal changes in COVID-19 hospitalized cases (2020) (40)
- Secondary Post-Geniculate Involvement in Leber’s Hereditary Optic Neuropathy (2012) (40)
- Profound vision loss impairs psychological well-being in young and middle-aged individuals (2017) (39)
- Vasculature and Morphometry of the Optic Canal and Intracanalicular Optic Nerve (1995) (39)
- Retinal nerve fiber layer evaluation in human immunodeficiency virus-positive patients. (2001) (39)
- Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy (2020) (38)
- Severe visual loss related to isolated peripapillary retinal and optic nerve head cytomegalovirus infection. (1989) (38)
- Pattern of early visual field loss in HIV-infected patients. (1999) (38)
- Brightness-sense and optic nerve disease. (1985) (37)
- An immunohistochemical study of TNF-alpha in optic nerves from AIDS patients. (1997) (37)
- Optic neuropathy in ethambutol-treated renal tuberculosis. (1987) (36)
- Colour vision defects in asymptomatic carriers of the Leber’s hereditary optic neuropathy (LHON) mtDNA 11778 mutation from a large Brazilian LHON pedigree: a case-control study (2006) (36)
- Retinal Nerve Fiber Layer Thickness Variability in Leber Hereditary Optic Neuropathy Carriers (2012) (35)
- Leber hereditary optic neuropathy possibly triggered by exposure to tire fire. (2006) (35)
- The optic neuropathy of Alzheimer's disease. (1989) (34)
- Association between retinal nerve fiber layer thickness and abnormalities of vision in people with human immunodeficiency virus infection. (2012) (34)
- Review: Orbital Amyloidosis (2004) (33)
- Optic nerve atrophy in propionic acidemia. (2003) (33)
- Visual Electrophysiologic Findings in Patients From an Extensive Brazilian Family with Leber's Hereditary Optic Neuropathy Visual electrophysiology in LHON (2004) (32)
- Optical coherence tomography can monitor reversible nerve-fibre layer changes in a patient with ethambutol-induced optic neuropathy (2007) (31)
- Rapid growth of an optic nerve ganglioglioma in a patient with neurofibromatosis 1. (1996) (30)
- Receptor for advanced glycation end products is upregulated in optic neuropathy of Alzheimer’s disease (2009) (30)
- Phosphorylated neurofilament heavy chain is a marker of neurodegeneration in Leber hereditary optic neuropathy (LHON) (2008) (30)
- Correlation of Fourier domain optical coherence tomography retinal nerve fiber layer maps with visual fields in nonarteritic ischemic optic neuropathy. (2008) (30)
- First application of extremely high-resolution magnetic resonance imaging to study microscopic features of normal and LHON human optic nerve. (2002) (29)
- Macular Microcysts in Mitochondrial Optic Neuropathies: Prevalence and Retinal Layer Thickness Measurements (2015) (29)
- Image enhancement improves reading performance in age-related macular degeneration patients (1998) (28)
- Changes in Choroidal Thickness follow the RNFL Changes in Leber’s Hereditary Optic Neuropathy (2016) (28)
- Multifocal electroretinography in HIV-positive patients without infectious retinitis. (2008) (28)
- Threshold Amsler grid as a screening tool for asymptomatic patients on hydroxychloroquine therapy (2005) (28)
- Intravitreal Gene Therapy vs. Natural History in Patients With Leber Hereditary Optic Neuropathy Carrying the m.11778G>A ND4 Mutation: Systematic Review and Indirect Comparison (2021) (27)
- Review of the visual system in Parkinson's disease. (1995) (27)
- The eye as metronome of the body. (2002) (27)
- Optic nerve histopathology in a case of Wolfram Syndrome: a mitochondrial pattern of axonal loss. (2013) (26)
- Distinguishing wet from dry age-related macular degeneration using three-dimensional computer-automated threshold Amsler grid testing (2011) (26)
- Is Leber hereditary optic neuropathy treatable? Encouraging results with idebenone in both prospective and retrospective trials and an illustrative case. (2012) (26)
- Effect of anticholinergic agents upon acquired nystagmus: A double-blind study of trihexyphenidyl and tridihexethyl chloride (1992) (26)
- Natural history of patients with Leber hereditary optic neuropathy—results from the REALITY study (2021) (25)
- Nuclear factor-κB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats (2006) (25)
- Comparison of visual function in fellow eyes after bilateral nonarteritic anterior ischemic optic neuropathy. (1997) (25)
- Retinal vessel calibre measurements by optical coherence tomography angiography (2016) (24)
- Ocular Loa Loa with cryoprobe extraction of subconjunctival worm. (1984) (24)
- Axonal and Cell Body Protection By Nicotinamide Adenine Dinucleotide in Tumor Necrosis Factor-Induced Optic Neuropathy (2009) (24)
- SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF THE OPTIC DISK IN OPTIC NEUROPATHY. (2016) (24)
- Aberrant regeneration of the third nerve following orbital trauma. Synkinesis of the iris sphincter. (1983) (23)
- Solar retinopathy. A biophysical analysis. (1984) (23)
- Visual improvement with the use of idebenone in the treatment of Wolfram syndrome. (2012) (23)
- Optical Coherence Tomography of the Retinal Ganglion Cell Complex in Leber’s Hereditary Optic Neuropathy and Dominant Optic Atrophy (2019) (23)
- Devastating complications from alcohol cauterization of recurrent Rathke cleft cyst. Case report. (2004) (23)
- V.B.8. Vitreous Floaters and Vision: Current Concepts and Management Paradigms (2014) (22)
- Ophthalmic education: where have we come from, and where are we going? (2003) (22)
- The Photopic Negative Response: An Objective Measure of Retinal Ganglion Cell Function in Patients With Leber's Hereditary Optic Neuropathy. (2017) (22)
- Optic neuropathy in Lhon and Leigh syndrome. (2001) (21)
- Alkaline tear pH in ocular rosacea. (1980) (21)
- OPTIC NERVE DEGENERATION IN ALZHEIMERʼS DISEASE (1986) (21)
- Visual evoked potentials findings in non-affected subjects from a large Brazilian pedigree of 11778 Leber’s hereditary optic neuropathy (2010) (21)
- The effects of aging vitreous on contrast sensitivity function (2018) (21)
- Human extraocular muscles in mitochondrial diseases: comparing chronic progressive external ophthalmoplegia with Leber’s hereditary optic neuropathy (2005) (20)
- The visual system in Alzheimer's disease. (1990) (20)
- Aspergillus keratitis with intraocular invasion. (1981) (20)
- Melanopsin-expressing retinal ganglion cells are resistant to cell injury, but not always. (2017) (20)
- Pupillometry evaluation of melanopsin retinal ganglion cell function and sleep-wake activity in pre-symptomatic Alzheimer’s disease (2019) (20)
- Ocular Changes in TgF 344-AD Rat Model of Alzheimer ’ s Disease (2014) (20)
- Neuro-ophthalmic complications of interleukin 2 therapy. (1991) (20)
- Quantifying Visual Dysfunction and the Response to Surgery in Macular Pucker. (2016) (20)
- Pentoxifylline suppression of TNF-alpha mediated axonal degeneration in the rabbit optic nerve. (1997) (19)
- The efficacy of optic nerve sheath decompression for anterior ischemic optic neuropathy and other optic neuropathies. (1993) (19)
- Cuban Epidemic Optic Neuropathy Mitochondrial DNA Analysis (1994) (19)
- Congenital ocular motor apraxia in twins. Findings with magnetic resonance imaging. (1987) (19)
- Morphometric analysis of optic nerves and retina from an end-stage retinitis pigmentosa patient with an implanted active epiretinal array. (2011) (19)
- Pattern of axonal loss in longstanding papilledema due to idiopathic intracranial hypertension. (1995) (19)
- Preliminary morphometric study of tumor necrosis factor-alpha (TNF alpha)-induced rabbit optic neuropathy. (1996) (19)
- Toxic medications in Leber's hereditary optic neuropathy. (2019) (18)
- Inner Retinal Layer Loss in Complicated Migraine (1988) (18)
- Focus on the Optic Nerve Head in Spaceflight-Associated Neuro-ocular Syndrome. (2019) (18)
- Threshold Amsler grid testing in diabetic retinopathy (2004) (18)
- Axonal Degeneration in Peripheral Nerves in a Case of Leber Hereditary Optic Neuropathy (2011) (17)
- Tonic pupils as a result of botulism. (1990) (17)
- Optical coherence tomography is a useful tool in the differentiation between true edema and pseudoedema of the optic disc (2018) (17)
- Lymphoepithelial carcinoma of the lacrimal gland. (2002) (16)
- Cuba: response of medical science to a crisis of optic and peripheral neuropathy (2004) (16)
- Effects of pentoxifylline on choroidal blood flow in nonproliferative diabetic retinopathy. (1994) (16)
- Nuclear factor-kappaB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats. (2006) (16)
- Glaucoma as Neurodegeneration in the Brain (2021) (16)
- Hertel Curve: Orbital Volume Increment and Proptosis in a Cadaver Model (2005) (16)
- In Reply: Optic and Peripheral Neuropathy in Cuba (1994) (16)
- Transmission of light through cataracts. (1990) (15)
- The retinal choroid as an oculovascular biomarker for Alzheimer's dementia: A histopathological study in severe disease (2019) (15)
- The role of mitochondria in health, ageing, and diseases affecting vision (2006) (15)
- Optical coherence tomography findings in deferasirox-related maculopathy. (2010) (15)
- Characterizing ethambutol‐induced optic neuropathy with a 3D computer‐automated threshold Amsler grid test (2008) (15)
- Spontaneous improvement of progressive anterior ischemic optic neuropathy: report of two cases. (1992) (14)
- Distinguishing between clinical impairments due to optic nerve or macular disease. (1990) (14)
- Correlation between static automated and scanning laser entoptic perimetry in normal subjects and glaucoma patients. (2000) (14)
- Orbital malignant peripheral nerve sheath tumors. Treatment with surgical resection and radiation therapy. (1993) (14)
- Long-Term Follow-Up After Unilateral Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy: The RESTORE Study (2020) (14)
- Proteomic Analysis of Embryonic and Young Human Vitreous. (2015) (14)
- Ultrastructural and paraphenylene studies of degeneration in the primate visual system: degenerative remnants persist for much longer than expected. (1988) (14)
- Chapter 111 – Optic Disc Pits and Associated Serous Macular Detachment (2006) (14)
- Chapter 93 – Optic Disc Anomalies, Pits, and Associated Serous Macular Detachment (2012) (13)
- Neuron specific enolase in retinal detachment (2001) (13)
- Death associated with an indwelling orbital catheter. (2003) (13)
- Comparing EPI-743 treatment in siblings with Leber's hereditary optic neuropathy mt14484 mutation. (2013) (13)
- Neuron-specific enolase is elevated in asymptomatic carriers of Leber's hereditary optic neuropathy. (2012) (13)
- Novel 3D Computer-Automated Threshold Amsler Grid Visual Field Testing of Scotomas in Patients with Glaucoma (2009) (12)
- The challenge of teaching ophthalmology: a Residency Review Committee perspective. (2000) (12)
- Retinal ganglion cell dysfunction in preclinical Alzheimer’s disease: an electrophysiologic biomarker signature (2021) (12)
- Neuro-ophthalmic manifestations of diabetes. (1999) (12)
- Histopathology and Ultrastructural Examination of Optic Nerve Sheath Biopsies After Optic Nerve Sheath Decompression With and Without Mitomycin (2001) (12)
- Oculomotor palsy with cyclic spasms (1989) (12)
- Model for optic nerve sheath decompression: Bernoulli's principle applied. (1991) (11)
- Prospective three-dimensional analysis of structure and function in vitreomacular adhesion cured by pharmacologic vitreolysis. (2013) (11)
- Cuban Epidemic Neuropathy: Insights into the Toxic-Nutritional Hypothesis through International Collaboration. (2018) (11)
- Immunolocalization of IL-1beta and IL-6 in optic nerves of patients with AIDS. (1999) (11)
- Optical coherence tomography for optic disc edema. (2011) (11)
- Why cataracts do not produce afferent pupillary defects. (1990) (11)
- Annual review in neuro-ophthalmology. The anterior visual pathways. (1994) (11)
- Impending anterior ischemic optic neuropathy with elements of retinal vein occlusion in a patient on interferon for polycythemia vera (2012) (10)
- Paradigm Shifts in Ophthalmic Diagnostics. (2016) (10)
- Cost Effectiveness of Limited Vitrectomy for Vision Degrading Myodesopsia. (2019) (10)
- Pathophysiology of Conversion to Symptomatic Leber Hereditary Optic Neuropathy and Therapeutic Implications: a Review (2020) (10)
- The Nervous System: Basic Science and Clinical Conditions (2008) (10)
- Abnormalities of the optic disc. (2011) (10)
- OCT parameters of the optic nerve head and the retina as surrogate markers of brain volume in a normal population, a pilot study (2020) (10)
- Chromatic Pupillometry Findings in Alzheimer’s Disease (2020) (10)
- Retinal dysfunction characterizes subtypes of dominant optic atrophy (2018) (10)
- Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers (2016) (10)
- Neuro-ophthalmology Safer Than MRI? (2013) (10)
- Inner retinal layer loss in complicated migraine. Case report. (1988) (10)
- Complete bilateral internal carotid artery occlusion in a young man. (1983) (10)
- Correcting Finger Counting to Snellen Acuity (2016) (9)
- Optical coherence tomography-angiography in Wolfram syndrome: a mitochondrial etiology in disease pathophysiology. (2019) (9)
- Leber's hereditary optic neuropathy: Severe vascular pathology in a severe primary mutation. (2019) (9)
- Correlation of optic disc morphometry and optic disc microvasculature assessed with optical coherence tomography angiography. (2018) (9)
- Optic and peripheral neuropathy in Cuba. (1994) (9)
- Regression of choroidal neovascularization after vitrectomy for postinjection endophthalmitis. (2010) (9)
- Dilantin-induced long-term bilateral total external ophthalmoplegia. (1986) (9)
- Gene Therapies for the Treatment of Leber Hereditary Optic Neuropathy (2021) (9)
- Low-Density Lipoprotein Receptor–Related Protein Is Decreased in Optic Neuropathy of Alzheimer Disease (2011) (8)
- Treatment of Leber's Hereditary Optic Neuropathy. (2017) (8)
- Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy (2022) (8)
- Leber's hereditary optic neuropathy: Shifting our attention to the macula (2018) (8)
- Phenotypic and functional characterization of Bst+/− mouse retina (2015) (8)
- Hormone replacement therapy in Leber's hereditary optic neuropathy: Accelerated visual recovery in vivo (2018) (8)
- Melanoma-Associated Retinopathy 28 Years After Diagnosis (2017) (8)
- Inner retinal optic neuropathy: vitreomacular surgery-associated disruption of the inner retina. (2014) (8)
- Basal cell epithelioma: an unusual case. (1981) (8)
- Alzheimer's disease and vision: correlation versus causation, revisited. (1990) (8)
- Inherited Optic Neuropathies (2010) (7)
- Optical Coherence Tomography in Alzheimer’s Disease (2020) (7)
- An International Study of Emotional Response to Bilateral Vision Loss Using a Novel Graphical Online Assessment Tool. (2017) (7)
- Melanopsin retinal ganglion cells and circadian dysfunction in Alzheimer´s disease (2013) (7)
- Response pattern asymmetry of binocular vision vertical fusion amplitudes in a normal population. (2008) (7)
- Headache and whiteout vision as the presenting symptoms in a case of Takayasu retinopathy. (2014) (7)
- OCTA in neurodegenerative optic neuropathies: emerging biomarkers at the eye–brain interface (2020) (7)
- Value of medical history in ophthalmology: A study of diagnostic accuracy (2018) (7)
- Near-fatal air embolus during arthrography of the hip in a baby aged four months. (2007) (7)
- Bright light stimuli as a mask of relative afferent pupillary defects. (1988) (6)
- Validity of Forced Eyelid Closure Test: A Novel Clinical Screening Test for Ocular Myasthenia Gravis (2017) (6)
- Choroidal thickness and the retinal ganglion cell complex in chronic Leberʼs hereditary optic neuropathy: a prospective study using swept-source optical coherence tomography (2019) (6)
- Idebenone Treatment in Patients With Leber Hereditary Optic Neuropathy (2009) (6)
- Optic neuropathies and retinal ganglion cell death (2000) (6)
- [Folic acid deficiency and increased concentrations of formate in serum and cerebrospinal fluid of patients with epidemic optical neuropathy]. (2000) (6)
- Mitochondrial optic neuropathies: additional facts and concepts – response (2014) (6)
- Characteristics of optic nerve damage induced by chronic intraocular hypertension in rat. (2004) (6)
- The anterior visual pathways. (1996) (5)
- Cross-Sectional Analysis of Baseline Visual Parameters in Subjects Recruited Into the RESCUE and REVERSE ND4-LHON Gene Therapy Studies (2021) (5)
- Occlusion-induced contralateral afferent pupillary defect. (1989) (5)
- Pentoxifylline: Clinical application in human immunodeficiency virus—associated optic neuropathy (1995) (5)
- Leber hereditary optic neuropathy. (1996) (5)
- Impaired Ganglion Cell Function Objectively Assessed by the Photopic Negative Response in Affected and Asymptomatic Members From Brazilian Families With Leber's Hereditary Optic Neuropathy (2021) (5)
- Optic Nerve Size and Constituent Components: Posterior Is More (2005) (5)
- Office Techniques for Detecting Optic Neuropathies Brightness Sense Compared to Traditional Screening Tests (1988) (5)
- Progressive cranial polyneuropathy caused by primary central nervous system melanoma. (1990) (5)
- Assessing vision in patients with Alzheimer's disease. (1988) (5)
- Optic Atrophy and Papilledema (2021) (5)
- The ophthalmology milestone project. (2014) (5)
- Leber’s hereditary optic neuropathy: new quinone therapies change the paradigm (2012) (5)
- A traumatic bitemporal hemianopia with macular sparing. (2005) (4)
- Malignant granular cell tumor of the posterior orbit (1990) (4)
- Optic neuritis or ophthalmic artery aneurysm? Case presentation with histopathologic documentation utilizing a new staining method. (1984) (4)
- Residual Psychophysical Deficits Following Recovery from the Cuban Epidemic of Optic Neuropathy (1997) (4)
- The Elusive Pathophysiology of Leber's Hereditary Optic Neuropathy (2016) (4)
- Optic Chiasm, Parasellar Region, and Pituitary Fossa (2009) (4)
- Retina and melanopsin neurons. (2021) (4)
- Intrachiasmal hemorrhage: A cause of delayed post-traumatic blindness (1989) (4)
- Optic nerve structure in healthy subjects. (2006) (4)
- Retinitis Pigmentosa Misdiagnosed as Complicated Migraine-Reply (1991) (4)
- Hereditary, Nutritional, and Toxic Optic Atrophies (2009) (4)
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- Optic Nerve Head Size Correlates With Penetrance in Maternal Lineages Belonging to the Same Large Brazilian SOA-BR Family With Leber’s Hereditary Optic Neuropathy (2007) (0)
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- Asymptomatic Carriers With Leber’s Hereditary Optic Neuropathy Often Demonstrate Visual Field Defects (2010) (0)
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- Functional Visual Outcome of 1st vs 2nd Affected Eye in Treated LHON Patients at 1 Year (2015) (0)
- Interleukin-10 (IL-10) after Ischemia Reperfusion Injury to the Rat Retina (2003) (0)
- Re: Chauhan et al.: Differential effects of aging in the macular retinal layers, neuroretinal rim, and peripapillary retinal nerve fiber layer (Ophthalmology. 2020;127:177-185). (2020) (0)
- A Morphological Study of the Optic Nerve in a Mito-Mouse Model Carrying an ND6 Point Mutation (2011) (0)
- Optic Nerve Head Morphology in Patients With OPA1-Related Dominant Optic Atrophy Suggests That OPA1 Influences Its Anatomical Conformation (2007) (0)
- Ultrastructural Features of TNF–alpha–Induced Optic Neuropathy in a Rat Model (2005) (0)
- Screening for Candidate Nuclear Modifying Genes in a Large Brazilian Pedigree with Leber’s Hereditary Optic Neuropathy (2006) (0)
- Contrast sensitivity, but not contrast gain, is affected in asymptomatic carriers of 11778 Leber’s Hereditary Optic Neuropathy (LHON) as assessed with the pedestal--pedestal protocol (2012) (0)
- Clinical trials for inherited optic neuropathies (2017) (0)
- RETINAL NERVE FIBER LAYER THINNING IN PRE-CLINICAL ALZHEIMER’S DISEASE PREDICTS CSF AMYLOID/TAU CLASSIFICATION (2019) (0)
- Chapter 43 – Leber's hereditary optic neuropathy (2010) (0)
- Mitochondrial Strain Index: Mathematically Modeling the Susceptibility of Optic Nerve Axons in Leber’s Hereditary Optic Neuropathy (2012) (0)
- Morphometry of axons in optic nerves of Siamese's twins. (2002) (0)
- Accuracy of ultrasonography, fundus photography, autofluorescence (AF), fluorescein angiography (FA), and optical coherence tomography (OCT) in differentiating pseudopapilledema from true optic disk edema (ODE) in children (2017) (0)
- Clinically-Significant Cardiac Pathology in Leber’s Hereditary Optic Neuropathy (2015) (0)
- Optic Nerve Axon Loss and Neuropsychological Impairment in HIV Encephalitis (2007) (0)
- Neuroprotective Effect of a TOPS-ester on Retinal Ischemia-Reperfusion Injury (2002) (0)
- Optic Neuropathy in a DNMT-1-Related Disease with a Mitochondrial Pattern of Axonal Loss (2016) (0)
- Why is the optic nerve the canary in the coal mine of mitochondrial diseases (2013) (0)
- Visual and Anatomic Findings after Discontinuation of Hydroxychloroquine in Patients Diagnosed with Toxicity (2012) (0)
- Reply to Should Tocilizumab Be Used Routinely in New Patients With a Diagnosis of Giant Cell Arteritis? (2021) (0)
- Understanding the onset of Leber's Hereditary Optic Neuropathy (2018) (0)
- Macular Dysfunction and Structure in Macular Pucker with Good Visual Acuity (2011) (0)
- Immunohistochemical Identification of Amyloid-Beta and Amyloid Precursor Protein in Alzheimer's Disease Optic Nerve and Retina (2009) (0)
- VALIDATION OF THE RETINAL NERVE FIBER LAYER AS AN OCULAR BIOMARKER IN ALZHEIMER’S DISEASE: A HISTOPATHOLOGIC INVESTIGATION (2018) (0)
- Pattern of Ganglion Cells and Nerve Fiber Layer Loss in Non-Arteritic Ischemic Optic Neuropathy determined by Fourier Domain Optical Coherence Tomography (2011) (0)
- Nicotinamide Mononucleotide Adenylyltransferase1 (Nmnat1) in TNF--Induced Optic Nerve Degeneration (2007) (0)
- Regulation of MnSOD protein expression in mammalian RGC axons in response to optic nerve crush–injury. (2004) (0)
- Prospective study of vitrectomy for floaters: improvement in contrast sensitivity and standardized VFQ testing (2013) (0)
- Cardiac Conduction in Leber’s Hereditary Optic Neuropathy (2014) (0)
- Circulating Antioxidants, Lipid Peroxidation Products, Cytokines and Neuron-specific Enolase in Leber’s Hereditary Optic Neuropathy (LHON) Patients (2003) (0)
- Optic Nerve Size May Reflect Pattern of Axonal Degeneration in Leber’s Hereditary Optic Neuropathy (2009) (0)
- Optic Nerve Histopathology in a Case of Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE) with Visual System Disturbances. (2004) (0)
- Morphological Analysis of Axonal Loss in TNF––Induced Optic Nerve Degeneration and Nicotinamide Adenine Dinucleotide (2006) (0)
- Melanopsin retinal ganglion cell-driven contribution to visual and cognitive brain responses in LHON (2020) (0)
- Cardiovascular comorbidity in Leber’s hereditary optic neuropathy mtDNA 11778 (2018) (0)
- RETINAL GANGLION CELL AND INNER PLEXIFORM LAYER THINNING IN PRE-CLINICAL ALZHEIMER’S DISEASE USING IN VIVO OPTICAL COHERENCE TOMOGRAPHY: ASSESSING EARLY DETECTION OF OCULAR BIOMARKERS (2018) (0)
- New concepts of treatment for LHON and other genetic mitochondrial optic neuropathies (2013) (0)
- Effects of Pentoxifylline on Blood Flow in Patients with Non-Arteritic Ischemic Optic Neuropathy (2014) (0)
- OCT Can Identify Reversible Nerve–fiber Layer Changes in a Patient With Ethambutol–induced Mitochondrial Pptic Neuropathy (2005) (0)
- Reduced pattern electroretinogram signal in affected patients with Leber Hereditary Optic Neuropathy (2019) (0)
- MITOCHONDRIAL DISEASE AND GLAUCOMA (2015) (0)
- Retinal Nerve Fiber Layer (RNFL) Assessment and Patterns of RNFL Loss in 200 Members of a LHON Brazilian Pedigree (2003) (0)
- Chapter 7 Optical Coherence Tomography in Alzheimer ’ s Disease (2016) (0)
- Indirect Comparison of Lenadogene Nolparvovec Gene Therapy versus Natural History in m.11778G>A MT-ND4 Leber Hereditary Optic Neuropathy Patients (S12.005) (2023) (0)
- A localized autophagic filter prevents entry of mitochondria carrying pathogenic Opa1 mutations in retinal ganglion cell axons (2016) (0)
- Protein KinaseC(PKC) and Cell Survival After Retinal Ischemic-Reperfusion Injury (2002) (0)
- Hereditary Optic Neuropathies (2020) (0)
- THE RETINAL CHOROID IN SEVERE ALZHEIMER’S DISEASE: A HISTOPATHOLOGICAL STUDY OF MORPHOLOGICAL CHANGES (2018) (0)
- Human Retinal Ganglion Cells Expressing an RGR Opsin: An Immunohistochemical Study (2020) (0)
- Long-term Follow-up of m.11778G>A MT-ND4-LHON Patients Treated with Lenadogene Nolparvovec Ocular Gene Therapy: the RESTORE Study (S12.004) (2023) (0)
- Assessment of Sleep Apnea in NAION Patients (2009) (0)
- Photopic Negative Response as an Objective Outcome Measure in Mitochondrial Disease (2018) (0)
- Alzheimer's Disease Optic Nerves Have Decreased Levels of Lipoprotein Receptor-Related Proteins (2010) (0)
- Hyalocytes in Macular Hole and Macular Pucker (2015) (0)
- An Ultrastructural Examination of the Optic Nerve in a Mouse Model for a Conditional Knockout Gene in Mitofusin 2 (2008) (0)
- Characterization of a Novel OPA1 Mouse Model by Light and Transmission Electron Microscopy (2014) (0)
- Searching for genetic modifiers of Leber's hereditary optic neuropathy penetrance (2012) (0)
- Altering neuronal circuitry with 4-aminopyridine for visual improvement in leber's hereditary optic neuropathy (LHON). (2021) (0)
- Re: Thompson: Much Ado about Nothing (or Something)-What Is the Role of Vitrectomy and Yttrium-Aluminum-Garnet Laser for Vitreous Floaters? (Ophthalmol Retina. 2018;2:879-880). (2019) (0)
- Treatment of Leber’s hereditary optic neuropathy patients with EPI-743 prevents decline of the serum biomarker - neuron specific enolase (2013) (0)
- Histopathologic Validation of Choroidal Thickness as a Biomarker for Leber's Hereditary Optic Neuropathy (LHON) (2018) (0)
- Mitochondrial optic neuropathies ( MON ) (2022) (0)
- Leber Hereditary Optic Neuropathy Conversion in a Patient With Idiopathic Intracranial Hypertension. (2022) (0)
- Differentiation of Optic Nerve from Retinal Macular Disease (2009) (0)
- Threshold Amsler Grid as a Screening Tool for Asymptomatic Patients with Hydroxychloroquine Maculopathy (2003) (0)
- Pupillary Light Responce in Blind Patients With Epiretinal Prostheses (2005) (0)
- Subjective Influences on Visual Acuity Testing Performance: A Prospective Study with Non-accommodating Intra-ocular Lenses (2013) (0)
- Microvascular changes in the retrobulbar optic nerve in idiopathic intracranial hypertension. (1999) (0)
- Computerized Morphometry to Quantify Choroidal Vasodilation in an Animal Model of Choroidal Neovascularization (2004) (0)
- Morphometric Analysis of Optic Nerve Axons Using Automated ArcGIS Feature Extraction (2016) (0)
- Judicious Resection and/or Radiosurgery for Parasagittal Meningiomas: Outcomes from a Multicenter Review (1998) (0)
- Morphometric Analysis of Optic Nerves In Leber's Hereditary Optic Neuropathy Reveals Preferential Loss Of Small Axons and Myelin Remodeling (2002) (0)
- Melanopsin Driven Pupillary Light Response in Leber’s Hereditary Optic Neuropathy (LHON) (2011) (0)
- Expression of NF-B and IB- in Rat Retinas Following Retinal Ischemia-Reperfusion Injury (2003) (0)
- Association between Vision Abnormalities and Increased Retinal Nerve Fiber Layer Thickness Among Individuals Infected with Human Immunodeficiency Virus (2011) (0)
- Distribution of Melanopsin Containing Retinal Ganglion Cells in Control and Mitochondrial Optic Neuropathy Subjects (2010) (0)
- Effects of Age and Vitreous Structure on Contrast Sensitivity (2016) (0)
- Quantifying Vision Beyond Visual Acuity in Macular Holes (2016) (0)
- C URRENT OPINION Mitochondrial dysfunction in optic neuropathies: animal models and therapeutic options (2013) (0)
- Chloramphenicol-Induced Optic Neuropathy in a Mouse Model: An Ultrastructural Study (2008) (0)
- Decreased Nicotinamide Adenine Dinucleotide (NAD) Level and the Effect of Exogenous NAD on Microglia Activation N TNF--Induced Optic Nerve Degeneration (2008) (0)
- Measurement of Reactive Oxygen Species Byproduct in Leber’s Hereditary Optic Neuropathy Affected and Carrier Patients (2007) (0)
- Immunohistochemical Evaluation of S100A12 (Calgranulin C) in Alzheimer Disease Optic Nerves (2009) (0)
- Vitreous Protein Profiles During the Second Trimester of Human Embryogenesis (2010) (0)
- Treatment of Leber's hereditary optic neuropathy with EPI‐743: the Brazilian experience (2015) (0)
- Using optical coherence tomography to map patterns of axonal degeneration in ethambutol–induced optic neuropathy (2004) (0)
- Linkage analysis in Leber’s hereditary optic neuropathy (LHON): failure to locate significant loci in a very large family indicates a polygenic/environmental complex contribution to penetrance (2013) (0)
- Prospective Evaluation Of Unaffected Carriers Belonging To A Large Lhon Family From Brazil: Results From Five Years Of Follow Up (2006) (0)
- Immunohistochemical Study of the Receptor for Advanced Glycation End Products in the Microvasculature of Alzheimer’s Optic Nerves (2009) (0)
- Improvements on a Method for Recognizing Colorblind Malingering (2015) (0)
- Analysis of Contrast Processing Segregated Into Magnocellular and Parvocellular Systems in Asymptomatic Carriers of 11778 LHON (2006) (0)
- Correlation of Automated Visual Field Parameters With Progression of Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) (2007) (0)
- Optical Coherence Tomography Angiography in Neuroophthalmology Review (2020) (0)
- Spontaneous Improvement of Progressive Anterior Ischemic Optic Neuropathy-Reply (1993) (0)
- Neuron Specific Enolase: A Potential Serological Marker for Predicting Phenotypic Expression in Carriers and Affected Patients With Leber's Hereditary Optic Neuropathy (2007) (0)
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What Schools Are Affiliated With Alfredo Arrigo Sadun?
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