Alison Motsinger-Reif
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American statistical geneticist
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Alison Motsinger-Reifbiology Degrees
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Mathematics Biology
Alison Motsinger-Reif's Degrees
- PhD Bioinformatics North Carolina State University
- Masters Statistics North Carolina State University
- Bachelors Statistics North Carolina State University
Why Is Alison Motsinger-Reif Influential?
(Suggest an Edit or Addition)According to Wikipedia, Alison Anne Motsinger-Reif is an American biostatistician and human geneticist specialized in association analyses, big data, and genomic analyses. In December 2018, she became the chief of the biostatistics and computational biology branch at the National Institute of Environmental Health Sciences. Montsinger-Reif was previously a professor of statistics at the North Carolina State University.
Alison Motsinger-Reif's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction (2007) (366)
- Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. (2010) (341)
- Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome (2018) (288)
- Metabolic network failures in Alzheimer's disease: A biochemical road map (2017) (280)
- CD1d-restricted Human Natural Killer T Cells Are Highly Susceptible to Human Immunodeficiency Virus 1 Infection (2002) (234)
- Alterations in metabolic pathways and networks in Alzheimer's disease (2013) (164)
- Shift Work in Nurses: Contribution of Phenotypes and Genotypes to Adaptation (2011) (155)
- An Introduction to Terminology and Methodology of Chemical Synergy—Perspectives from Across Disciplines (2017) (154)
- Auriculotherapy for pain management: a systematic review and meta-analysis of randomized controlled trials. (2010) (153)
- Multifactor dimensionality reduction: An analysis strategy for modelling and detecting gene - gene interactions in human genetics and pharmacogenomics studies (2006) (152)
- Genome-wide association studies in pharmacogenomics: successes and lessons (2013) (150)
- Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study. (2010) (141)
- Variation in the Glucose Transporter gene SLC2A2 is associated with glycaemic response to metformin (2016) (139)
- Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL. (2013) (117)
- Comparison of approaches for machine‐learning optimization of neural networks for detecting gene‐gene interactions in genetic epidemiology (2008) (113)
- Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity. (2006) (111)
- Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways. (2011) (108)
- CYP2C8*3 increases risk of neuropathy in breast cancer patients treated with paclitaxel. (2013) (104)
- GPNN: Power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease (2006) (97)
- Characterization of Conserved and Nonconserved Imprinted Genes in Swine1 (2009) (97)
- Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation. (2007) (96)
- Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior (2011) (93)
- Multifactor dimensionality reduction for detecting gene-gene and gene-environment interactions in pharmacogenomics studies. (2005) (90)
- CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel (2012) (87)
- Refining tumor-associated aneuploidy through ‘genomic recoding’ of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas (2011) (86)
- Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study (2015) (77)
- Genetic basis for adverse events after smallpox vaccination. (2008) (75)
- Multilocus genetic interactions and response to efavirenz-containing regimens: an Adult AIDS Clinical Trials Group study (2006) (75)
- Feature Selection using a Random Forests Classifier for the Integrated Analysis of Multiple Data Types (2006) (75)
- Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination (2009) (73)
- Data Simulation Software for Whole-Genome Association and Other Studies in Human Genetics (2005) (72)
- Polymorphisms in IL-1β, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis (2010) (72)
- Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study. (2006) (71)
- Characterization of canine osteosarcoma by array comparative genomic hybridization and RT‐qPCR: Signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart (2011) (71)
- An adaptive permutation approach for genome-wide association study: evaluation and recommendations for use (2014) (70)
- α-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance (2016) (69)
- International collaborative study to assess cardiovascular risk and evaluate long‐term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study (2018) (68)
- Genetic programming neural networks: A powerful bioinformatics tool for human genetics (2007) (65)
- Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants (2016) (65)
- Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas. (2013) (63)
- Association of dilated cardiomyopathy with the striatin mutation genotype in boxer dogs. (2013) (62)
- Gene set analysis methods: a systematic comparison (2018) (61)
- Untargeted Metabolomic Profiling Identifies Disease-specific Signatures in Food Allergy and Asthma. (2019) (61)
- Novel methods for detecting epistasis in pharmacogenomics studies. (2007) (60)
- A comparison of analytical methods for genetic association studies (2008) (59)
- Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero (2016) (58)
- Insights into the inhibition of platelet activation by omega-3 polyunsaturated fatty acids: beyond aspirin and clopidogrel. (2011) (56)
- The effect of reduction in cross‐validation intervals on the performance of multifactor dimensionality reduction (2006) (55)
- Multifactor dimensionality reduction reveals gene–gene interactions associated with multiple sclerosis susceptibility in African Americans (2006) (54)
- Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy. (2008) (52)
- Identification and Simian Immunodeficiency Virus Infection of CD1d-Restricted Macaque Natural Killer T Cells (2003) (51)
- Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma (2014) (51)
- Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization (2015) (50)
- Canine urothelial carcinoma: genomically aberrant and comparatively relevant (2015) (48)
- Pharmacogenomic characterization of US FDA-approved cytotoxic drugs. (2011) (47)
- Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer (2011) (47)
- Evaluation of genetic risk score models in the presence of interaction and linkage disequilibrium (2013) (47)
- Human Natural Killer T Cells Are Heterogeneous in Their Capacity to Reprogram Their Effector Functions (2006) (47)
- Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging (2013) (46)
- Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota (2012) (46)
- Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy (2014) (40)
- The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine learning (2020) (40)
- Morphologic and Molecular Analysis of 39 Spontaneous Feline Pulmonary Carcinomas (2012) (40)
- Targeted metabolomics and medication classification data from participants in the ADNI1 cohort (2017) (39)
- Complex gene–gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes (2006) (38)
- Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial (2016) (37)
- Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking (2019) (36)
- Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24 (2014) (35)
- ABCB1 and GST polymorphisms associated with TP53 status in breast cancer (2007) (34)
- Comparison of Neural Network Optimization Approaches for Studies of Human Genetics (2006) (33)
- Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes (2015) (33)
- Association of breed and histopathological grade in canine mast cell tumours (2017) (33)
- A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT (2012) (33)
- Genetic variation in the mitochondrial enzyme carbamyl-phosphate synthetase I predisposes children to increased pulmonary artery pressure following surgical repair of congenital heart defects: a validated genetic association study. (2007) (32)
- Novel human genetic variants associated with extrapulmonary tuberculosis: a pilot genome wide association study (2011) (31)
- Initial evaluation of nighttime restlessness in a naturally occurring canine model of osteoarthritis pain (2015) (30)
- Power of grammatical evolution neural networks to detect gene-gene interactions in the presence of error (2008) (30)
- Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction (2013) (29)
- An R package implementation of multifactor dimensionality reduction (2011) (29)
- Relationship between mechanical thresholds and limb use in dogs with coxofemoral joint oa-associated pain and the modulating effects of pain alleviation from total hip replacement on mechanical thresholds. (2014) (28)
- Cumulative Genetic Risk Predicts Platinum/Taxane-Induced Neurotoxicity (2013) (27)
- Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans (2016) (27)
- Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes (2018) (27)
- Grammatical evolution decision trees for detecting gene-gene interactions (2010) (26)
- Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study (2020) (26)
- Neural networks for genetic epidemiology: past, present, and future (2008) (26)
- Bayesian neural networks for detecting epistasis in genetic association studies (2014) (25)
- Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes (2018) (24)
- Alfaxalone anesthesia in bullfrogs (Lithobates catesbeiana) by injection or immersion. (2013) (24)
- A comparison of internal validation techniques for multifactor dimensionality reduction (2010) (24)
- Risk Factor Interactions and Genetic Effects Associated with Post-Operative Atrial Fibrillation (2005) (23)
- Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial (2018) (23)
- CD 1 d-restricted Human Natural Killer T Cells Are Highly Susceptible to Human Immunodeficiency Virus 1 Infection (2002) (23)
- The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and progesterone addback (2017) (23)
- Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation (2015) (23)
- A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. (2016) (22)
- Comparison of venous sampling methods for thromboelastography in clinically normal dogs. (2012) (22)
- Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines. (2014) (22)
- Evaluation of polymorphisms in the sulfonamide detoxification genes NAT2, CYB5A, and CYB5R3 in patients with sulfonamide hypersensitivity (2012) (21)
- Embracing Integrative Multiomics Approaches (2016) (21)
- Effects of acepromazine maleate on platelet function assessed by use of adenosine diphosphate activated- and arachidonic acid- activated modified thromboelastography in healthy dogs. (2012) (20)
- Operative factors associated with short-term outcome in horses with large colon volvulus: 47 cases from 2006 to 2013. (2015) (19)
- Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics (2017) (19)
- Lymphoblastoid cell lines models of drug response: successes and lessons from this pharmacogenomic model. (2014) (18)
- A New Explained-Variance Based Genetic Risk Score for Predictive Modeling of Disease Risk (2012) (18)
- PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid (2020) (18)
- Beyond IC50s: Towards Robust Statistical Methods for in vitro Association Studies (2014) (18)
- Multivariate methods and software for association mapping in dose‐response genome‐wide association studies (2012) (18)
- Understanding the Evolutionary Process of Grammatical Evolution Neural Networks for Feature Selection in Genetic Epidemiology (2006) (17)
- A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies (2019) (17)
- Loss of Power in Two‐Stage Residual‐Outcome Regression Analysis in Genetic Association Studies (2012) (16)
- Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD (2017) (16)
- Relative Quantification and Higher-Order Modeling of the Plasma Glycan Cancer Burden Ratio in Ovarian Cancer Case-Control Samples. (2015) (16)
- A Comparison of Association Methods for Cytotoxicity Mapping in Pharmacogenomics (2011) (16)
- Identification and Replication of Loci Involved in Camptothecin-Induced Cytotoxicity Using CEPH Pedigrees (2011) (15)
- Differences in X-Chromosome Transcriptional Activity and Cholesterol Metabolism between Placentae from Swine Breeds from Asian and Western Origins (2013) (15)
- Accuracy of SNPs to predict risk of HLA alleles associated with drug-induced hypersensitivity events across racial groups. (2015) (15)
- The effect of alternative permutation testing strategies on the performance of multifactor dimensionality reduction (2008) (15)
- The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning (2021) (15)
- Human genomic association studies: a primer for the infectious diseases specialist. (2007) (15)
- Evaluation of thromboelastography for prediction of clinical bleeding in thrombocytopenic dogs after total body irradiation and hematopoietic cell transplantation. (2014) (15)
- Alternative cross-over strategies and selection techniques for grammatical evolution optimized neural networks (2006) (14)
- Clinical applications of whole-genome association studies: future applications at the bedside (2006) (14)
- Prevalence of onychectomy in cats presented for veterinary care near Raleigh, NC and educational attitudes toward the procedure. (2014) (14)
- Genome-Wide Association Study in Immunocompetent Patients with Delayed Hypersensitivity to Sulfonamide Antimicrobials (2016) (14)
- A novel canine model of immune thrombocytopenia: has immune thrombocytopenia (ITP) gone to the dogs? (2014) (13)
- Gene selection and cancer type classification of diffuse large-B-cell lymphoma using a bivariate mixture model for two-species data (2013) (13)
- Comparative Exposure Assessment Using Silicone Passive Samplers Indicates Domestic Dogs are Sentinels to Support Human Health Research. (2020) (13)
- Current Methods for Quantifying Drug Synergism. (2019) (12)
- Can Neural Network Constraints in GP Provide Power to Detect Genes Associated with Human Disease? (2005) (12)
- Thromboelastographic monitoring of the effect of unfractionated heparin in healthy dogs (2017) (12)
- Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial (2017) (12)
- A Comparison of Multifactor Dimensionality Reduction and L1-Penalized Regression to Identify Gene-Gene Interactions in Genetic Association Studies (2011) (12)
- Positive association between a glutathione-S-transferase polymorphism and lymphoma in dogs. (2014) (12)
- A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies (2016) (12)
- Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate (2018) (12)
- Exploring epistasis in candidate genes for rheumatoid arthritis (2007) (12)
- Multifactor Dimensionality Reduction as a Filter-Based Approach for Genome Wide Association Studies (2011) (12)
- Genomic Profiling in CEPH Cell Lines Distinguishes between the Camptothecins and Indenoisoquinolines (2011) (11)
- Carboplatin/taxane-induced gastrointestinal toxicity: a pharmacogenomics study on the SCOTROC1 trial (2015) (11)
- Assessing the utility of whole genome amplified DNA as a template for DMET Plus array (2012) (11)
- Optimization of Nonlinear Dose- and Concentration-Response Models Utilizing Evolutionary Computation (2011) (11)
- Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts (2019) (10)
- Genomic map of candidate human imprint control regions: the imprintome (2022) (10)
- A comparison of DMET Plus microarray and genome-wide technologies by assessing population substructure (2016) (9)
- VH1-44 gene usage defines a subset of canine B-cell lymphomas associated with better patient survival. (2014) (9)
- Long‐term incidence and risk of noncardiovascular and all‐cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy (2019) (8)
- Global tests of P-values for multifactor dimensionality reduction models in selection of optimal number of target genes (2012) (8)
- Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes (2016) (8)
- Grammatical evolution support vector machines for predicting human genetic disease association (2012) (8)
- Interaction between Genetic Risk Scores for reduced pulmonary function and smoking, asthma and endotoxin (2021) (8)
- Functional genomic approaches for the study of fetal/placental development in swine with special emphasis on imprinted genes. (2020) (8)
- Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells. (2020) (7)
- Community-Based Testing Sites for SARS-CoV-2 — United States, March 2020–November 2021 (2021) (7)
- Evaluation of polymorphisms in the sulfonamide detoxification genes CYB5A and CYB5R3 in dogs with sulfonamide hypersensitivity. (2012) (7)
- Evaluating the role of admixture in cancer therapy via in vitro drug response and multivariate genome-wide associations. (2015) (7)
- Quality of Reporting on Randomised Controlled Trials of Auriculotherapy for Pain (2011) (7)
- A comparison of internal model validation methods for multifactor dimensionality reduction in the case of genetic heterogeneity (2012) (7)
- The influence of packed cell volume versus plasma proteins on thromboelastographic variables in canine blood. (2020) (7)
- Linkage Disequilibrium in Genetic Association Studies Improves the Performance of Grammatical Evolution Neural Networks (2007) (7)
- Pharmacogenetic Analysis of the Model‐Based Pharmacokinetics of Five Anti‐HIV Drugs: How Does This Influence the Effect of Aging? (2017) (6)
- The power of quantitative grammatical evolution neural networks to detect gene-gene interactions (2011) (6)
- Ex-Vivo Modeling for Heritability Assessment and Genetic Mapping in Pharmacogenomics. (2011) (6)
- Cheminformatics approach to exploring and modeling trait-associated metabolite profiles (2019) (6)
- Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex (2019) (6)
- The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: monitoring county level vulnerability (2020) (5)
- Genetic and environmental risk for lymphoma in boxer dogs (2020) (5)
- Fibrate pharmacogenomics: expanding past the genome. (2020) (5)
- In vitro iatrogenic hemolysis of canine packed red blood cells during various rapid transfusion techniques. (2020) (5)
- The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs. (2017) (5)
- Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy. (2016) (5)
- Comprehensive genomic characterization of five canine lymphoid tumor cell lines (2016) (5)
- A Type 2 Diabetes Subtype Responsive to ACCORD Intensive Glycemia Treatment (2021) (5)
- ' s response to reviews Title : Polymorphisms in IL-1 beta , Vitamin D Receptor Fok 1 , and Toll-like Receptor 2 Are Associated with Extrapulmonary Tuberculosis (2009) (4)
- Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics (2014) (4)
- Identifying individual risk rare variants using protein structure guided local tests (POINT) (2019) (4)
- Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine. (2013) (4)
- Stress Drivers of Glucose Dynamics during Ozone Exposure Measured Using Radiotelemetry in Rats (2022) (4)
- Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis (2022) (4)
- International collaborative study to assess cardiovascular risk and evaluate long‐term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study (2018) (4)
- A Bayesian Framework for the Analysis of the Peroxisome Proliferator-Activated Receptor Signaling Pathway (4)
- A balanced accuracy fitness function leads to robust analysis using grammatical evolution neural networks in the case of class imbalance (2008) (4)
- Software for genome-wide association studies having multivariate responses: Introducing MAGWAS (2012) (4)
- Same-Species Contamination Detection with Variant Calling Information from Next Generation Sequencing (2019) (4)
- The Effect of Retrospective Sampling on Estimates of Prediction Error for Multifactor Dimensionality Reduction (2011) (4)
- Prediction of synergistic drug combinations using PCA-initialized deep learning (2021) (3)
- Institutional profile. UNC Institute for Pharmacogenomics and Individualized Therapy: interdisciplinary research for individual care. (2010) (3)
- Linkage Disequilibrium between ABO and Rh Loci in Barak Valley Populations vis-à-vis a Few Exotic Populations (2011) (3)
- Nonlinear Dose–Response Modeling of High-Throughput Screening Data Using an Evolutionary Algorithm (2020) (3)
- Glucose dynamics during ozone exposure measured using radiotelemetry: Stress drivers (2021) (3)
- Optimization of grammatical evolution decision trees (2011) (3)
- Knockoff boosted tree for model-free variable selection (2020) (3)
- Interrogation of polymorphisms in drug metabolism or transport genes and peripheral neuropathy during paclitaxel treatment. (2012) (3)
- PGxClean: a quality control GUI for the Affymetrix DMET chip and other candidate gene studies with non-biallelic alleles (2014) (3)
- Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines (2019) (3)
- Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response (2016) (3)
- Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (2021) (3)
- Statistical Applications in Genetics and Molecular Biology A Comparison of Multifactor Dimensionality Reduction and L1-Penalized Regression to Identify Gene-Gene Interactions in Genetic (2011) (2)
- Clinical trial evidence of the promise of pharmacogenomics warfarin dosing algorithms. (2012) (2)
- ACE I/D Polymorphism Modulates Symptomatic Response to Antiarrhythmic Drug Therapy in Patients with Lone Atrial Fibrillation (2007) (2)
- Orals (2014) (2)
- Gene expression and linkage analysis implicate CBLB as a mediator of rituximab resistance (2017) (2)
- The Role of Hepatic Vagal Tone in Ozone-Induced Metabolic Dysfunction in the Liver. (2021) (2)
- Characterizing Canine Lymphoma As a Potential Large Animal Model of Human Diffuse Large B-Cell Lymphoma (2011) (2)
- A Genetic Response Score for Hydrochlorothiazide UseNovelty and Significance (2016) (2)
- Erratum to: Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics (2014) (2)
- An investigation of gene-gene interactions in dose-response studies with Bayesian nonparametrics (2015) (2)
- PGxClean: a quality control GUI for the Affymetrix DMET chip and other candidate gene studies with non-biallelic alleles (2014) (1)
- Genetic Basis for Adverse Events Following Smallpox Vaccination (2019) (1)
- Discussion of a genome-wide association approach to determine HIV-1 set point in African Americans. (2010) (1)
- A comparison of internal model validation methods for multifactor dimensionality reduction in the case of genetic heterogeneity (2012) (1)
- Prediction of synergistic drug combinations using PCA-initialized deep learning (2021) (1)
- Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study. (2022) (1)
- Untargeted Metabolomic Profiling Identifies Disease‐Specific Pathways in Food Allergy and Asthma: 773 (2019) (1)
- INDICES OF PLASMALOGEN BIOSYNTHESIS IN ADNI-1 BASELINE SERUM SAMPLES: ASSOCIATION WITH PROGRESSION TO DEMENTIA IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT (2016) (1)
- Current Study Designs, Methods, and Future Directions of Genetic Association Mapping (2015) (1)
- High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs (2021) (1)
- Untargeted Metabolomic Profiling Identifies Disease-specific Profiles in Food Allergy (2019) (1)
- Developments in Analyses in Pharmacogenetic Datasets (2012) (1)
- ToxicR: A computational platform in R for computational toxicology and dose-response analyses. (2022) (1)
- Integrating Metabolomics And Genomics Reveals Novel Biomarkers Of Hydrochlorothiazide Response In Pharmacogenomic Evaluation Of Antihypertensive Responses (pear) Study: Qp-04 (2015) (1)
- Genetic markers associated with platinum/taxanesinduced gastrointestinal toxicity in SCOTROC1trial (2011) (1)
- Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction (2013) (1)
- Abstract PD10-07: Patients carrying CYP2C8*3 are at increased risk of paclitaxel-induced neuropathy (2012) (1)
- Bayesian neural networks for detecting epistasis in genetic association studies (2014) (1)
- Gene selection and cancer type classification of diffuse large-B-cell lymphoma using a bivariate mixture model for two-species data (2013) (1)
- Replication study of CYP4F2 association with warfarin response in an Israeli population. (2012) (1)
- Interview: a discussion on genome-wide associations in pharmacogenomics. (2013) (1)
- Abstract PD07-10: Breast Cancer Patients Carrying the CYP2C8*3 Variant Are More Likely To Achieve Clinical Complete Response from Neoadjuvant Paclitaxel Treatment (2010) (1)
- Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging (2013) (1)
- Software for detecting gene-gene interactions using Multifactor Dimensionality Reduction: Introducing the R package MDR (2010) (1)
- An adaptive permutation approach for genome-wide association study: evaluation and recommendations for use (2014) (1)
- GECCO ’14: Proceedings of the 2014 conference on Genetic and evolutionary computation (2014) (1)
- Multivariate methods and software for association mapping in dose‐response genome‐wide association studies (2012) (1)
- The influence of Neanderthal alleles on cytotoxic response (2018) (1)
- Implementing machine learning methods with complex survey data: Lessons learned on the impacts of accounting sampling weights in gradient boosting (2023) (1)
- Blood Lead Toxicity Analysis of Multipurpose Canines and Military Working Dogs. (2018) (0)
- Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions (2022) (0)
- Oral Session III (2015) (0)
- 321-OR: A Genetic Locus on Chromosome 1p36 Associated with Cardiovascular Autonomic Neuropathy in Type 2 Diabetes (2019) (0)
- GUT DERIVED BILE ACID METABOLITES CORRELATE WITH STRUCTURAL AND FUNCTIONAL NEUROIMAGING MEASURES IN ALZHEIMER’S DISEASE (2017) (0)
- GENETIC INFLUENCE ON LEVELS OF TARGETED METABOLITES ASSOCIATED WITH ALZHEIMER’S DISEASE (2016) (0)
- A comparison of analytical methods for genetic association studies (2009) (0)
- The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells (2022) (0)
- Are plasma level and CYP genotypes predictors of liver injury in an Ethiopian population? (2012) (0)
- Author's response to reviews Title: Grammatical Evolution Decision Trees for Detecting Gene-Gene Interactions Authors: (2010) (0)
- 143-OR: Mapping Genetic Determinants of Blood Glucose Control in the Action to Control Cardiovascular Risk in Diabetes Study Group (ACCORD) (2022) (0)
- Visualization, benchmarking and characterization of nested single-cell heterogeneity as dynamic forest mixtures (2022) (0)
- Leveraging Lymphoblastoid Cell Lines for Drug Response Modeling (2015) (0)
- Single-Nucleotide Polymorphism Data Support the General Unrelatedness of the Males in the Agricultural Health Study (2014) (0)
- Differentially Expressed MicroRNAs Revealed by Molecular Signatures of Preeclampsia and IUGR in Human Placenta. (2012) (0)
- Association of distance to swine concentrated animal feeding operations with immune-mediated diseases: An exploratory gene-environment study. (2022) (0)
- Identifying individual risk rare variants using protein structure-guided local tests (POINT) (2018) (0)
- Higher Criticism Tuned Regression For Weak And Sparse Signals (2020) (0)
- A predictive model for efavirenz dosing. (2012) (0)
- Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort (2022) (0)
- University of Groningen Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking Sikdar, (2019) (0)
- 262: Molecular signatures of preeclampsia in human term placentas (2008) (0)
- ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS (2021) (0)
- Metagenomics reveals novel microbial signatures of farm exposures in house dust (2023) (0)
- Thanks to Referees (1998) (0)
- An investigation of gene-gene interactions in dose-response studies with Bayesian nonparametrics (2015) (0)
- Canine urothelial carcinoma: genomically aberrant and comparatively relevant (2015) (0)
- Division of Intramural Research-NAEHS Council Update (2009) (0)
- Extending the lymphoblastoid cell line model for drug combination pharmacogenomics. (2021) (0)
- Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization (2014) (0)
- ' s report Title : Predicting the Difficulty of Pure , Strict , Epistatic Models : Metrics for Simulated Model Selection Version : 1 Date : 23 June 2012 (0)
- University of Dundee Genetic Variants in CPA6 and PRPF31 are Associated with Variation in Response to Metformin in Individuals with Type 2 Diabetes Rotroff, (2018) (0)
- methods software for association mapping in dose-response genome-wide association studies. (2013) (0)
- Global tests of P-values for multifactor dimensionality reduction models in selection of optimal number of target genes (2012) (0)
- Treatment trends with immune checkpoint inhibitor (ICI) therapy in older adults with lung cancer. (2020) (0)
- Exposome-Wide Association Studies (ExWAS) Reveal Expected and Novel Risk Factors Associated with Cardiovascular Outcomes in the Personalized Environment and Genes Study (2021) (0)
- POSTER SESSION II (2015) (0)
- LBMON114 Enrichment Of Rare Sequence Variants In Genes That Communicate Metabolic Signals To The GnRH System In Hypothalamic Amenorrhea (2022) (0)
- International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats (2018) (0)
- ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS (2022) (0)
- Session details: Graduate workshop (2012) (0)
- The skin is no barrier to mixtures: Air pollutant mixtures and reported psoriasis or eczema in the Personalized Environment and Genes Study (PEGS). (2022) (0)
- A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes (2018) (0)
- Same-species Contamination Detection With Variant Calling Information From Next-generation Sequencing (2021) (0)
- Do genetic polymorphisms of nevirapine metabolic, transport and antigen recognition enzymes play a role in nevirapine toxicity risk? (2012) (0)
- Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen (2019) (0)
- Abstract 1487: Gene expression and linkage analysis implicates CBLB as a mediator of rituximab resistance (2016) (0)
- Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex (2019) (0)
- Erratum to: Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics (2014) (0)
- Embracing Complexity: Searching for Gene-Gene and Gene Environment Interactions in Genetic Epidemiology (2015) (0)
- Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes (2016) (0)
- THE ALZHEIMER’S METABOLOME: RELATIONSHIP TO PATHOLOGICAL MARKERS AND COGNITIVE DECLINE IN THE ALZHEIMER’S DISEASE NEUROIMAGING INITIATIVE (ADNI) (2016) (0)
- Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation (2015) (0)
- ALFAXALONE ANESTHESIA IN BULLFROGS (LITHOBATES CATESBEIANA) BY INJECTION OR IMMERSION (2013) (0)
- Erratum: Abstract OIII-B-1: Genetic markers associated with platinum/taxanes-induced gastrointestinal toxicity in SCOTROC1 Trial (Clinical Pharmacology and Therapeutics (2011) 89 (S66) DOI:10.1038/clpt.2010.334) (2011) (0)
- The Polymorphisms in the Vitamin D Receptor Gene and Disease Severity in Sickle Cell Disease (2015) (0)
- Abstract 13621: Integrating Metabolomics and Genomics Uncovers Novel Pathways and Genetic Signatures Influencing Hydrochlorothiazide Blood Pressure Response: A Genetic Response Score for Hydrochlorothiazide Use (2015) (0)
- Race and smoking status associated with paclitaxel drug response in patient-derived lymphoblastoid cell lines. (2020) (0)
- Acknowledgement to the Reviewers (2009) (0)
- A novel canine model of immune thrombocytopenia: Has ITP gone to the dogs? (2014) (0)
- Abstract LB-177: Novel approaches for improving interpretation and predictive models of comparative genomic hybridization data (2015) (0)
- Pathway Analysis and Its Applications (2015) (0)
- Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics (2014) (0)
- Gene set analysis methods: a systematic comparison (2018) (0)
- Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts (2019) (0)
- Pain relief improves sleep in dogs with osteoarthritis (2015) (0)
- Crime, Violence, and Suspensions in Traditional Versus Public Charter Schools: Large Scale Evidence From One U.S. State (2020) (0)
- A comparison of GE optimized neural networks and decision trees (2012) (0)
- Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero (2016) (0)
- Molecular and Cellular Pathobiology Gene Pro fi ling of Canine B-Cell LymphomaReveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times , Modeling Human DLBCL (2013) (0)
- University of Dundee Variation in the Glucose Transporter gene SLC 2 A 2 is associated with glycaemic response to metformin (2016) (0)
- Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma (2014) (0)
- Correlation Analysis of Variables From the Atherosclerosis Risk in Communities Study (2022) (0)
- The Vitamin D Receptor Gene and Disease Severity in Sickle Cell Anemia (2011) (0)
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