Alissa M. Weaver
#103,875
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American oncologist
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Alissa M. Weaverphilosophy Degrees
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Philosophy
Alissa M. Weaver's Degrees
- PhD Biomedical Engineering Johns Hopkins University
Why Is Alissa M. Weaver Influential?
(Suggest an Edit or Addition)According to Wikipedia, Alissa Margaret Weaver is an American oncologist. In 2017, she was promoted to the Cornelius Vanderbilt Endowed Chair of Cell and Developmental Biology and Pathology, Microbiology and Immunology at the Vanderbilt University School of Medicine.
Alissa M. Weaver's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines (2018) (5288)
- Extracellular Vesicles: Unique Intercellular Delivery Vehicles. (2017) (893)
- Tumor Morphology and Phenotypic Evolution Driven by Selective Pressure from the Microenvironment (2006) (707)
- Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation (2001) (595)
- Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. (2007) (455)
- Invadopodia: Specialized Cell Structures for Cancer Invasion (2006) (425)
- Directional cell movement through tissues is controlled by exosome secretion (2015) (416)
- Cortactin Localization to Sites of Actin Assembly in Lamellipodia Requires Interactions with F-Actin and the Arp2/3 Complex (2000) (413)
- Exosome secretion is enhanced by invadopodia and drives invasive behavior. (2013) (412)
- 3D collagen alignment limits protrusions to enhance breast cancer cell persistence. (2014) (316)
- Extracellular Matrix Rigidity Promotes Invadopodia Activity (2008) (314)
- Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin (2017) (307)
- KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes (2016) (292)
- Cortactin Promotes Cell Motility by Enhancing Lamellipodial Persistence (2005) (284)
- KRAS-dependent sorting of miRNA to exosomes (2015) (264)
- Interaction of Cortactin and N-WASp with Arp2/3 Complex (2002) (262)
- Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes (2016) (260)
- N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses* (2008) (229)
- Cortactin in tumor invasiveness. (2008) (223)
- Integration of signals to the Arp2/3 complex. (2003) (206)
- Cortactin promotes exosome secretion by controlling branched actin dynamics (2016) (202)
- A new role for cortactin in invadopodia: regulation of protease secretion. (2008) (183)
- Cortactin Interacts with WIP in Regulating Arp2/3 Activation and Membrane Protrusion (2003) (182)
- Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility (2017) (175)
- Signaling inputs to invadopodia and podosomes (2013) (173)
- Cortactin: a multifunctional regulator of cellular invasiveness. (2011) (149)
- Adhesion rings surround invadopodia and promote maturation (2012) (141)
- The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research (2019) (120)
- Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma. (2021) (118)
- Sensing and modulation of invadopodia across a wide range of rigidities. (2011) (117)
- A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells (2020) (113)
- Mathematical modeling of cancer: the future of prognosis and treatment. (2005) (107)
- Embryonic Fibroblasts That Are Genetically Deficient in Low Density Lipoprotein Receptor-related Protein Demonstrate Increased Activity of the Urokinase Receptor System and Accelerated Migration on Vitronectin* (1997) (98)
- CAS promotes invasiveness of Src-transformed cells (2004) (93)
- Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells. (2018) (89)
- Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon (2008) (89)
- Regulation of cancer invasiveness by the physical extracellular matrix environment (2009) (85)
- Exosome secretion promotes chemotaxis of cancer cells (2017) (84)
- Cortactin Controls Cell Motility and Lamellipodial Dynamics by Regulating ECM Secretion (2011) (79)
- Dependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidence. (2008) (77)
- Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKCα Invasive Signaling Axis (2012) (75)
- Biogenesis, delivery, and function of extracellular RNA (2015) (72)
- Establishment and Validation of Computational Model for MT1-MMP Dependent ECM Degradation and Intervention Strategies (2012) (68)
- Regulation of invadopodia by mechanical signaling. (2016) (66)
- PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin–actin interactions (2015) (64)
- EPHB2 carried on small extracellular vesicles induces tumor angiogenesis via activation of ephrin reverse signaling. (2019) (63)
- Microenvironmental independence associated with tumor progression. (2009) (62)
- A Three-Dimensional Computational Model of Collagen Network Mechanics (2014) (60)
- Human Mammary Epithelial Cells Exhibit a Bimodal Correlated Random Walk Pattern (2010) (55)
- Quantitative Proteomic Analysis of Small and Large Extracellular Vesicles (EVs) Reveals Enrichment of Adhesion Proteins in Small EVs. (2019) (53)
- Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition (2013) (47)
- Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling (2010) (47)
- Arp2/3 Complex Advances on the Inner Workings of a Molecular Machine (2001) (42)
- Regulation of late endosomal/lysosomal maturation and trafficking by cortactin affects Golgi morphology (2012) (42)
- Extracellular vesicles: important collaborators in cancer progression. (2018) (42)
- Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop. (2018) (40)
- Regulation of Cancer Invasion by Reactive Oxygen Species and Tks Family Scaffold Proteins (2009) (39)
- Epidermal Growth Factor and Platelet-derived Growth Factor-BB Induce a Stable Increase in the Activity of Low Density Lipoprotein Receptor-related Protein in Vascular Smooth Muscle Cells by Altering Receptor Distribution and Recycling* (1996) (39)
- Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity. (1995) (35)
- Invadopodia (2008) (35)
- Extracellular vesicles: Critical players during cell migration. (2021) (34)
- Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein. (2015) (33)
- Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer* (2015) (31)
- Arrestins regulate cell spreading and motility via focal adhesion dynamics (2015) (29)
- Cortactin (2011) (29)
- Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles (2020) (29)
- Laminin‐332–β1 integrin interactions negatively regulate invadopodia (2009) (28)
- Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling (2021) (27)
- Bimodal Analysis of Mammary Epithelial Cell Migration in Two Dimensions (2008) (26)
- Modeling heterogeneous tumor growth dynamics and cell-cell interactions at single-cell and cell-population resolution. (2019) (26)
- A mathematical model quantifies proliferation and motility effects of TGF-β on cancer cells. (2007) (26)
- LDL receptor family-dependent and -independent pathways for the internalization and digestion of lipoprotein lipase-associated beta-VLDL by rat vascular smooth muscle cells. (1997) (25)
- Native and Activated Forms of α2-Macroglobulin Increase Expression of Platelet-derived Growth Factor α-Receptor in Vascular Smooth Muscle Cells (1995) (24)
- Response of head and neck squamous cell carcinoma cells carrying PIK3CA mutations to selected targeted therapies. (2015) (24)
- VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites. (2022) (22)
- Role of adenosine A2B receptor signaling in contribution of cardiac mesenchymal stem-like cells to myocardial scar formation (2014) (19)
- MISEV 2018 ) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV 2014 guidelines (2018) (17)
- Use of monoclonal anti-light subunit antibodies to study the structure and function of theEntamoeba histolytica Gal/GalNAc adherence lectin (1994) (17)
- Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through β1 integrin, Src and ERK 1/2 (2016) (17)
- Mutant Cu,Zn superoxide dismutase in motor neuron disease. (1998) (15)
- α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration (2018) (14)
- pHluo_M153R-CD63, a bright, versatile live cell reporter of exosome secretion and uptake, reveals pathfinding behavior of migrating cells (2019) (14)
- WAVE2 Regulates Epithelial Morphology and Cadherin Isoform Switching through Regulation of Twist and Abl (2013) (14)
- Regulation of lysosomal secretion by cortactin drives fibronectin deposition and cell motility (2011) (14)
- Hyperinsulinemia After Pancreatic Transplantation: Prediction by a Novel Computer Model and In Vivo Verification (1993) (12)
- Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement. (2022) (12)
- Synthetic and tissue-derived models for studying rigidity effects on invadopodia activity. (2013) (12)
- Argonautes in extracellular vesicles: artifact or selected cargo? (2019) (12)
- Activated α2-Macroglobulin Reverses the Immunosuppressive Activity in Human Breast Cancer Cell‐Conditioned Medium by Selectively Neutralizing Transforming Growth Factor-β in the Presence of Interleukin‐2 (1998) (12)
- Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness (2015) (11)
- Directed migration: Cells navigate by extracellular vesicles (2018) (11)
- Proteinases are isoform-specific regulators of the binding of transforming growth factor beta to alpha 2-macroglobulin. (1996) (11)
- Stable antisense RNA expression neutralizes the activity of low-density lipoprotein receptor-related protein and promotes urokinase accumulation in the medium of an astrocytic tumor cell line. (1999) (10)
- Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer. (2022) (10)
- Protrusion of a Virtual Model Lamellipodium by Actin Polymerization: A Coarse-Grained Langevin Dynamics Model (2008) (9)
- Cell–Cell Fusion: A New Function for Invadosomes (2011) (7)
- A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells (2020) (7)
- Context-specific regulation of extracellular vesicle biogenesis and cargo selection. (2023) (5)
- Native and activated forms of alpha 2-macroglobulin increase expression of platelet-derived growth factor alpha-receptor in vascular smooth muscle cells. Evidence for autocrine transforming growth factor-beta activity. (1995) (5)
- Biogenesis of RNA-containing extracellular vesicles at endoplasmic reticulum membrane contact sites (2020) (4)
- “ Cortactin and tumor invasiveness” (2008) (4)
- Cytoskeletal interactions with the outside world. (2005) (4)
- Sunitinib and Axitinib increase secretion and glycolytic activity of small extracellular vesicles in renal cell carcinoma (2021) (3)
- Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences (2021) (3)
- Proteinases are isoform-specific regulators of the binding of transforming growth factor b to a 2 -macroglobulin (1996) (2)
- Autocrine Role of Exosomes in Cellular Adhesion, Migration, and Invasion (2017) (1)
- Author response: KRAS-dependent sorting of miRNA to exosomes (2015) (1)
- ER Membrane Contact Sites: Key Platforms for Biogenesis of RNA-Containing Extracellular Vesicles (2022) (0)
- Faculty Opinions recommendation of Migrasome formation is mediated by assembly of micron-scale tetraspanin macrodomains. (2019) (0)
- Niche tension controls exosome production (2023) (0)
- Abstract 4176: Identifying analytes associated with poor prognosis in CRC (2014) (0)
- Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement. (2022) (0)
- Extracellular vesicles from non-neuroendocrine SCLC cells promote adhesion and survival of neuroendocrine SCLC cells (2022) (0)
- Immunosuppressive Effects of TGF-B Produced by Human Breast Cancer Cells Can be Blocked by Activated ??2-Macroglobulin (1996) (0)
- Science Signaling Podcast: 11 September 2012 (2012) (0)
- Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles (2020) (0)
- Extracellular Matrix Degradation by Invadopodia (2007) (0)
- Announcing the ISEV2020 special achievement award recipients: Andrew Hill and Edit Buzás; and the recipient of the ISEV2020 special education award: Carolina Soekmadji (2020) (0)
- Visualization of Exosome Release and Uptake During Cell Migration Using the Live Imaging Reporter pHluorin_M153R-CD63. (2023) (0)
- A2B adenosine receptors promote retention of cardiac stem cells in a myofibroblast‐like state induced by myocardial infarction (652.11) (2014) (0)
- Parameters for elastic collagen fiber network simulations. (2014) (0)
- Meeting Abstracts of the American Society for Exosomes and Microvesicles 2020 Annual Meeting (2020) (0)
- EV Fingerprinting: Resolving extracellular vesicle heterogeneity using multi-parametric flow cytometry (2022) (0)
- Cortactin in invadopodia formation (2006) (0)
- Meeting Abstracts of the first meeting of the American Society for Intercellular Communication 2021 (2022) (0)
- Cortactin regulates Golgi size by controlling retrograde trafficking from late endosomes (2011) (0)
- The Role of Targeted Therapy and Oncogene Dependence on the PIK3CA Mutation (2014) (0)
- Mathematical Oncology Microenvironmental Independence Associated with Tumor Progression (2009) (0)
- Report Extracellular Matrix Rigidity Promotes Invadopodia Activity (2008) (0)
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