Allan Victor Hoffbrand

Allan Victor Hoffbrand's AcademicInfluence.com Rankings

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Philosophy

Why Is Allan Victor Hoffbrand Influential?

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According to Wikipedia, Allan Victor Hoffbrand is Emeritus Professor of Haematology at University College, London. He is distinguished for his research and as an author of internationally read textbooks of haematology. He was born in Bradford, Yorkshire in 1935. After education at Bradford Grammar School, he gained an Open Scholarship in 1953 to The Queen's College, Oxford. He gained a BA degree in Physiology and began clinical studies at The London Hospital in 1957 and qualified in medicine at University of Oxford, BM BCH in 1959.

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Allan Victor Hoffbrand's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Method of assay of red cell folate activity and the value of the assay as a test for folate deficiency (1966) (320)
TUMOUR NECROSIS FACTOR AS AN AUTOCRINE TUMOUR GROWTH FACTOR FOR CHRONIC B-CELL MALIGNANCIES (1988) (283)
Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia (1993) (268)
Philadelphia positive acute lymphoblastic leukemia in adults: age distribution, BCR breakpoint and prognostic significance. (1991) (251)
Clearance of skin lesions in dermatitis herpetiformis after gluten withdrawal. (1973) (214)
Tissue antibodies in dermatitis herpetiformis and adult coeliac disease. (1971) (204)
Minimal residual disease tests provide an independent predictor of clinical outcome in adult acute lymphoblastic leukemia. (2002) (195)
Progress in the diagnosis and management of aspergillosis in bone marrow transplantation: 13 years' experience. (1993) (184)
Small-intestinal structure and function and haematological changes in dermatitis herpetiformis. (1967) (178)
1,2-DIMETHYL-3-HYDROXYPYRID-4-ONE, AN ORALLY ACTIVE CHELATOR FOR TREATMENT OF IRON OVERLOAD (1987) (171)
KETOCONAZOLE VERSUS NYSTATIN PLUS AMPHOTERICIN B FOR FUNGAL PROPHYLAXIS IN SEVERELY IMMUNOCOMPROMISED PATIENTS (1982) (144)
A study of proximal and distal intestinal structure and absorptive function in idiopathic steatorrhoea. (1967) (142)
Role of autoimmune gastritis, Helicobacter pylori and celiac disease in refractory or unexplained iron deficiency anemia. (2005) (138)
Acyclovir prophylaxis against herpes virus infections in severely immunocompromised patients: randomised double blind trial. (1983) (135)
Endogenously generated activated killer cells circulate after autologous and allogeneic marrow transplantation but not after chemotherapy. (1989) (134)
Minimal residual disease is a significant predictor of treatment failure in non T‐lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993 (2010) (133)
Circulating immune complexes in dermatitis herpetiformis. (1973) (131)
Mechanism of folate deficiency in patients receiving phenytoin. (1968) (126)
Anti-reticulin antibodies in childhood coeliac disease. (1971) (125)
Lymphocytic Infiltration of Epithelium in Diagnosis of Gluten-sensitive Enteropathy (1972) (125)
In vivo induction of gamma interferon and tumor necrosis factor by interleukin-2 infusion following intensive chemotherapy or autologous marrow transplantation. (1989) (118)
IMMUNE DONORS CAN PROTECT MARROW-TRANSPLANT RECIPIENTS FROM SEVERE CYTOMEGALOVIRUS INFECTIONS (1987) (117)
Effect of gluten-free diet on dermatological, intestinal, and haematological manifestations of dermatitis herpetiformis. (1968) (113)
Immunoglobulins in the skin in dermatitis herpetiformis and coeliac disease. (1972) (103)
The hematologic complications following partial gastrectomy. A study of 292 patients. (1967) (97)
Absorption of crystalline folic acid in man. (1968) (96)
Folate deficiency in Crohn's disease: incidence, pathogenesis, and treatment. (1968) (94)
The small intestine in dermatitis herpetiformis (1974) (92)
Antireticulin antibody: Incidence and diagnostic significance (1973) (91)
A phase I clinical trial of recombinant interleukin 2 following high dose chemo-radiotherapy for haematological malignancy: applicability to the elimination of minimal residual disease. (1989) (88)
Rituximab in the treatment of refractory autoimmune cytopenias in adults. (2005) (84)
Effects of interferon alpha on autocrine growth factor loops in B lymphoproliferative disorders (1990) (81)
Stomatococcus mucilaginosus: an emerging pathogen in neutropenic patients. (1992) (75)
Rearrangement of immunoglobulin and T cell antigen receptor genes in acute myeloid leukemia with lymphoid-associated markers. (1987) (69)
The effect of vitamin B12 deficiency on methylfolate metabolism and pteroylpolyglutamate synthesis in human cells. (1974) (68)
Gluten-free diet and reintroduction of gluten in dermatitis herpetiformis. (1969) (66)
Sideroblastic Anaemia and its Association with Leukaemia and Myelomatosis: A Report of Five Cases (1971) (63)
Tissue distribution of coenzyme and other forms of vitamin B12 in control subjects and patients with pernicious anaemia. (1974) (61)
Evidence for intestinal origin of transcobalamin II during vitamin B12 absorption. (1978) (56)
The subcellular localization of pteroyl polyglutamate hydrolase and folate in guinea pig intestinal mucosa. (1969) (55)
Chaetomium pneumonia in patient with acute myeloid leukaemia. (1996) (53)
Alternate-pathway complement fixation by IgA in the skin in dermatitis herpetiformis. (1973) (52)
High serum-folate levels in intestinal blind-loop syndrome. (1966) (49)
Serum ferritin concentration in Gaucher's disease. (1983) (46)
Effect of Fasting (2017) (44)
Splenic Atrophy in Dermatitis Herpetiformis (1972) (44)
Chromatographic and bioautographic estimation of plasma cobalamins in various disturbances of vitamin B12 metabolism. (1971) (43)
The contribution of large granular lymphocytes to B cell activation and differentiation after T-cell-depleted allogeneic bone marrow transplantation. (1986) (42)
Expression of the E2A-PBX1 fusion transcripts in t(1;19)(q23;p13) and der(19)t(1;19) at diagnosis and in remission of acute lymphoblastic leukemia with different B lineage immunophenotypes. (1995) (40)
Cytotoxic effects of tumour necrosis factor and gamma-interferon on acute myeloid leukaemia blasts. (1987) (39)
Absorption of Vitamin B12 by the Guinea‐Pig I. SUBCELLULAR LOCALIZATION OF VITAMIN B12 IN THE ILEAL ENTEROCYTE DURING ABSORPTION * (1970) (39)
Streptococcus mitis and ARDS in neutropenic patients (1991) (39)
Iron and folate metabolism in tuberculosis. (1966) (39)
LEIOMYOSARCOMA OF THE INFERIOR VENA CAVA LEADING TO OBSTRUCTION OF THE TRICUSPID VALVE (1964) (39)
Folate deficiency in premature infants. (1970) (37)
Safety and Effectiveness of 100 mg/kg/day Deferiprone in Patients with Thalassemia Major: A Two-Year Study (2005) (37)
Neurological involvement in hereditary transcobalamin II deficiency. (1982) (37)
V(H) gene usage differs in germline and mutated B-cell chronic lymphocytic leukemia. (2003) (36)
Unbalanced Deoxyribonucleotide Synthesis Caused by Methotrexate (1972) (36)
Incidence and pathogenesis of megaloblastic erythropoiesis in multiple myeloma (1967) (36)
Response to phytohaemagglutinin and pokeweed mitogen in chronic lymphocytic leukaemia. (1972) (36)
Genotypes and immunophenotypes of Hodgkin's disease-derived cell lines. (1988) (36)
B cell development and regulation after T cell-depleted marrow transplantation. (1987) (36)
Mixed acute leukaemias. (1988) (35)
Immunoglobulin heavy-chain gene rearrangement in adult acute lymphoblastic leukemia reveals preferential usage of J(H)-proximal variable gene segments. (2001) (34)
Minimal residual disease monitoring in adult T-cell acute lymphoblastic leukemia: a molecular based approach using T-cell receptor G and D gene rearrangements. (2002) (34)
THE MECHANISM OF FOLATE DEFICIENCY IN PSORIASIS (1971) (34)
Variable kappa gene rearrangement in lymphoproliferative disorders: an analysis of V kappa gene usage, VJ joining and somatic mutation. (1994) (33)
Oral contraceptives and folate metabolism. (1972) (32)
THE PERIPHERAL NERVES AND SKELETAL MUSCLES IN WEGENER'S GRANULOMATOSIS: A CLINICO-PATHOLOGICAL STUDY OF FOUR CASES. (1965) (31)
Malabsorption of Folate Polyglutamates in Tropical Sprue (1969) (31)
Synthesis of folate polyglutamates in human cells. (1976) (31)
Rearrangement and expression of T cell antigen receptor genes in B cell chronic lymphocytic leukemia (1988) (31)
Vitamin B12 Status in Pregnancy among Immigrants to Britain (1973) (30)
Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin. (1970) (30)
Recombinant interferon alfa 2 a in the treatment of patients with early stage B chronic lymphocytic leukaemia (1993) (30)
Folate Assays: Serum or Red Cell? (1997) (30)
The Excretion of Methylmalonic Acid and Succinic Acid in Vitamin B12 and Folate Deficiency (1967) (29)
Heavy metal intoxication from homeopathic and herbal remedies. (1994) (28)
Serum Folate and Vitamine B12 Levels in Acute and Chronic Renal Disease. Effect of Peritoneal Dialysis (1969) (28)
Malabsorption of Dietary Folate (Pteroylpolyglutamates) in Adult Coeliac Disease and Dermatitis Herpetiformis (1970) (27)
Leucocyte Folate in Vitamin B12 and Folate Deficiency and in Leukaemia (1967) (26)
Small intestinal bacterial flora and folate status in gastrointestinal disease (1971) (26)
Correlation of immunophenotype with rearrangement of T cell antigen receptor beta and gamma genes in acute lymphoblastic leukemia of adults. (1988) (26)
DCC tumor suppressor gene is inactivated in hematologic malignancies showing monosomy 18. (1993) (25)
In vitro analysis of the interactions of recombinant IL-2 with regenerating lymphoid and myeloid cells after allogeneic marrow transplantation. (1988) (25)
Polyglutamate forms of folate in resting and proliferating mammalian tissues. (1975) (25)
Synthesis of cobalamin coenzymes by human lymphocytes in vitro and the effect of folates and metabolic inhibitors. (1976) (23)
Five-Year Trial of Deferiprone Chelation Therapy in Thalassaemia major Patients (2004) (23)
Molecular analysis of minimal residual disease in adult acute lymphoblastic leukaemia. (2002) (23)
Composition of pteroylpolyglutamates (conjugated folates) in guinea-pig liver and their formation from folic acid. (1972) (22)
Increased Agglutinability by Anti‐i of Red Cells in Sideroblastic and Megaloblastic Anaemia (1968) (21)
Rearrangement and expression of T cell antigen receptor genes in B cell chronic lymphocytic leukemia. (1988) (21)
The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients. (2001) (21)
Association of 17p loss with late-stage or refractory disease in hematologic malignancy. (1994) (21)
MEGALOBLASTIC ANAEMIA IN MYELOSCLEROSIS (1968) (20)
Studies on the uptake of synthetic conjugated folates by human marrow cells. (1973) (20)
Hepatic protein binding of folate. (1974) (20)
Impairment of folate absorption by systemic bacterial infections. (1974) (19)
Cytokine‐induced enhancement of the susceptibility of hairy cell leukaemia lymphocytes to natural killer cell lysis (1988) (18)
Bone-marrow aspiration and trephine biopsy (1). (1980) (18)
Absorption of Vitamin B12 in the Guinea‐Pig III. THE FORMS OF VITAMIN B12 IN ILEAL MUCOSA AND PORTAL PLASMA IN THE FASTING STATE AND DURING ABSORPTION OF CYANOCOBALAMIN (1971) (17)
Subcellular localization of folate and effect of methotrexate on the incorporation of radioactive folic acid into guinea-pig liver folate. (1972) (16)
Membrane phenotype and response to deoxycoformycin in mature T cell malignancies. (1987) (16)
Serum Lactic Dehydrogenase Activity and Folate Deficiency in Myelosclerosis and other Haematological Diseases (1966) (16)
IL-4 acts as a homeostatic regulator of IL-2-induced TNF and IFN-gamma. (1991) (16)
Chromosome studies in megaloblastic anaemia before and after treatment. (2009) (16)
Delivery of Vitamin B12 to Human Lymphocytes by Transcobalamins I, II and III 1 (1974) (15)
Hereditary abnormal transcobalamin II previously diagnosed as congenital dihydrofolate reductase deficiency. (1984) (14)
What does apoptosis mean in CLL? (1996) (14)
Long-term clearance of [57Co]cyanocobalamin in vegans and pernicious anaemia. (1980) (13)
Variable Philadelphia breakpoints and potential lineage restriction of bcr rearrangement in acute lymphoblastic leukemia. (1988) (13)
Bone marrow transplant recipients have defective MHC-unrestricted cytotoxic responses against cytomegalovirus in comparison with Epstein-Barr virus: the importance of target cell expression of lymphocyte function-associated antigen 1 (LFA1). (1992) (12)
A randomized trial of empirical antibiotic therapy with one of four beta-lactam antibiotics in combination with netilmicin in febrile neutropenic patients. (1988) (12)
Effects of tumour necrosis factor and alpha interferon on chronic B cell malignancies. (1988) (12)
DIFFERENTIAL RECOVERY OF PHENOTYPICALLY AND FUNCTIONALLY DISTINCT CIRCULATING ANTIGEN‐PRESENTING CELLS AFTER ALLOGENEIC MARROW TRANSPLANTATION (1988) (12)
Absorption of Vitamin B12 by the Guinea‐Pig (1971) (12)
T-cell receptor gene rearrangement in B-cell non-Hodgkin's lymphoma: correlation with methylation and expression. (1989) (11)
Bilateral osteonecrosis of the head of the femur complicating acute promyelocytic leukemia: a sequel to treatment of retinoic acid syndrome with dexamethasone. (1996) (11)
A comparison of double beta-lactam combinations with netilmicin/ureidopenicillin regimens in the empirical therapy of febrile neutropenic patients. (1989) (11)
Inter conversion of cobalamins in human lymphocytes in vitro and the influence of nitrous oxide on synthesis of cobalamin coenzymes (1979) (11)
Jejunal pH and folic acid. (1971) (11)
Absorptive capacity of the jejunum of obese and lean subjects: effect of fasting. (1972) (11)
Low-dose recombinant alfa-2a-interferon: a feasible maintenance therapy in acute myeloid leukaemia in the older patient. (1993) (10)
Hereditary transcobalamin II deficiency: a 22 year follow up. (1997) (10)
Transcobalamin II deficiency: long-term follow-up of two cases. (1988) (9)
VH gene usage differs in germline and mutated B-cell chronic lymphocytic leukemia (9)
Specific and non-specific folate binding protein in normal and malignant human tissues (1978) (9)
Folate Deficiency in Polycythaemia Rubra Vera (1965) (8)
A Familial Abnormality of Circulating Vitamin B12 Binding Proteins: Occurrence in a Family of High Serum Concentrations of Transcobalamin II (1976) (8)
1 Genetic changes: Relevance for diagnosis and detection of minimal residual disease in acute lymphoblastic leukaemia (1994) (8)
Molecular confirmation of invasive infection caused by Chaetomium globosum. (2005) (8)
Recombinant Alpha 2A Interferon-An Effective Maintenance Agent in Essential Thrombocythaemia. (1990) (8)
Recovery of immunoglobulin isotypes following T-cell depleted allogeneic bone marrow transplantation. (1986) (8)
Bone-marrow aspiration and trephine biopsy (2). (1980) (8)
Sephadex-gel filtration and heat stability of human jejunal and serum pteroylpolyglutamate hydrolase (folate conjugase). Evidence for two different forms. (1975) (7)
Gastro-intestinal flora and diarrhoea after vagotomy. (1971) (7)
THE EXCRETION OF FORMIMINOGLUTAMIC ACID AND UROCANIC ACID AFTER PARTIAL GASTRECTOMY (1966) (7)
The effects of chemotherapy on iron, folate, and vitamin B 12 metabolism in tuberculosis. (1971) (7)
Effect of methotrexate on absorption of folates. (1972) (7)
Interleukin-2 infusion after autologous bone marrow transplantation enhances hemopoietic regeneration. (1991) (6)
Do double-beta-lactam combinations prolong neutropenia in patients undergoing chemotherapy or bone marrow transplantation for hematological disease? (1989) (6)
Fludarabine and psoriasis. (1994) (6)
Interleukin-3 plus low-dose cytosine arabinoside for advanced myelodysplasia: a pilot study. EORTC Leukemia Group. (1996) (6)
Prolonged remission of Epstein-Barr virus associated lymphoma secondary to T cell-depleted bone marrow transplantation. (1988) (6)
Treatment of myelodysplastic syndromes (MDS) and high leukaemic risk with low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating factor (rh GM-CSF) (1992) (5)
Recent advances in knowledge of clinical and biochemical aspects of folate. (1970) (5)
Spontaneous splenic rupture in myelodysplastic syndrome. (1989) (4)
Professor John Scott, folate and neural tube defects (2014) (4)
The effect of dietary folate deficiency on the synthesis of methylcobalamin in the chick. (2009) (4)
Pathology of folate deficiency. (1977) (4)
Folate Deficiency inCrohn's Disease: Incidence, Pathogenesis, andTreatment (1968) (4)
Folate absorption (1971) (4)
Estimation of individual plasma B 12 compounds in normal subjects and patients with deranged B 12 metabolism. (1969) (4)
Response to phytohaemagglutinin and pokeweed mitogen in chronic lymphocytic leukemia. (1972) (4)
Subcellular localization of folate conjugase in guinea-pig intestinal mucosa. (1969) (4)
Polyglutamyl forms of folate acid in man. (1969) (4)
Successful surgical management of septic arthritis due to Trichosporon beigelii in a patient with acute myeloid leukaemia. (1992) (4)
Rituximab Does Not Increase the Complication Rate, Particularly Perforation, When Added to Chemotherapy for Patients with Primary B-Cell Lymphomas of the Gastrointestinal Tract. (2005) (3)
Subcellular localization of radioactive vitamin B12 during absorption by guinea-pig ileum. (1969) (3)
The forms of vitamin B 12 in the ileal enterocyte of the guinea-pig during fasting and absorption of cyanocobalamin. (1970) (3)
Oligoclonality: an insight into the biology of acute lymphoblastic leukaemia (2001) (2)
Folate absorption and malabsorption (2005) (2)
TNF and chronic B lymphoproliferative disorders. (1993) (2)
Frequency of JAK2 Exon 12 Mutations in JAK2 Exon 14 V617F-Negative Patients: High Frequency in ET Patients. (2007) (2)
Dermatitis herpetiformis. (1974) (2)
Effect of drugs which cause megaloblastosis on the free intracellular pools of DNA precursors. (1973) (2)
Mandatory UK folic acid fortification (2021) (2)
Methodofassay ofredcell folate activity andthe value oftheassay asatest forfolate deficiency (1966) (2)
Recombinant alpha-2a interferon in the treatment of patients with early stage B chronic lymphocytic leukaemia (1993) (2)
Automation in Perspective (1967) (1)
Minimal Residual Disease in Acute Leukaemia (2007) (1)
Randomized phase II study LD-ARAC plus rhGM-CSF in advanced myelodysplasia (1993) (1)
Synthesis and breakdown of natural folates (folate polyglutamates). (1975) (1)
Pathology of Vitamin Abnormality (1977) (1)
Bone-marrow aspiration. (1981) (1)
Recent Advances in the Megaloblastic Anaemias (1971) (1)
METHYMALONIC ACIDURIA (1970) (1)
FOLIC-ACID ABSORPTION IN MAN (1968) (1)
SOUTHERN BLOTTING ANALYSIS DEMONSTRATES THAT DEL13Q14 IS A PRIMARY CLONAL EVENT WHILE TRISOMY-12 IS A SECONDARY EVENT IN CHRONIC LYMPHOCYTIC-LEUKEMIA (CLL) (1994) (0)
A RAPID METHOD FOR THE DETECTION OF CLONAL-B CELL EXPANSION AND MINIMAL RESIDUAL DISEASE (MRD) IN ALL BY THE POLYMERASE CHAIN-REACTION (PCR) (1993) (0)
Selective malabsorption of vitamin B12 without proteinuria or structural renal tract anomaly. (1977) (0)
Haematology in the UK: A 60‐year personal perspective (2021) (0)
chronic lymphocytic leukemia Rearrangement and expression of T cell antigen receptor genes in B cell (2011) (0)
Hemizygous deletion and translocations involving the 13q14 region in acute leukemia and non-Hodgkin lymphoma (NHL). (1995) (0)
Long-Term Precision of Carcinoembryonic Antigen Assays (2004) (0)
677C->T mutation of the 5,10-methylene tetrahydrofolate reductase gene: Relationship with occlusive coronary disease (1997) (0)
A phase Iclinical trial ofrecombinant interleukin 2following highdose chemo-radiotherapy forhaematological malignancy: applicability tothe elimination ofminimal residual disease (1989) (0)
Analysis of VH gene usage in chronic lymphocytic leukemia. (1995) (0)
Malabsorption ofFolate Polyglutamates inTropical Sprue (1969) (0)
VH Gene Usage, Frame Coding and Mutational Status Analysis in Adults with Acute Lymphoblastic Leukaemia (Adult ALL). (2005) (0)
Malabsorption and the skin. (1968) (0)
Incorporation of radioactive folic acid into liver folate. (1972) (0)
Subject Index Vol. 112, 2004 (2004) (0)
Distribution of coenzyme and other forms of vitamin B12 within human tissues. (1973) (0)
Molecular analysis of the leukemic B cell in adult and childhood acute lymphoblastic leukemia (1995) (0)
Cells Studies on the Uptake of Synthetic Conjugated Folates by Human Marrow (2011) (0)
English delftware apothecary jars and their contents (2017) (0)
The excretion of foriminoglutamic acid and urocanic acid after partial gastrectomy. (1966) (0)
LEIOMYOSARCOMAOF THE INFERIORVENA CAVA LEADINGTO OBSTRUCTION OF THE TRICUSPIDVALVE (1964) (0)
The Association of Clinical Pathologists: 83rd General Meeting Estimation of Individual Plasma B12 Compounds in Normal Subjects and Patients with Deranged B12 Metabolism Some Haematological Aspects of Renal Transplantation (0)
Deoxyribonucleoside Triphosphates in Human Cells: Changes in Disease and Following Exposure to Drugs (1975) (0)
Contents Vol. 112, 2004 (2004) (0)
Molecular Investigation of Minimal Residual Disease in Adult Acute Lymphoblastic Leukemia of B Lineage (2003) (0)
Conserved amino acid sequences occur in a limited group of CLL patients with predominantly mutated IGH rearrangements (2004) (0)
leukemia reveals preferential usage of JH-proximal variable gene segments Immunoglobulin heavy-chain gene rearrangement in adult acute lymphoblastic (2013) (0)

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