Allison Hubel
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Allison Hubelengineering Degrees
Engineering
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Biomedical Engineering
#877
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Engineering
Allison Hubel's Degrees
- PhD Biomedical Engineering University of California, Berkeley
- Masters Biomedical Engineering University of California, Berkeley
- Bachelors Biomedical Engineering Stanford University
Why Is Allison Hubel Influential?
(Suggest an Edit or Addition)According to Wikipedia, Allison Hubel is an American mechanical engineer and cryobiologist who applies her expertise in heat transfer to study the cryopreservation of biological tissue. She is a professor of mechanical engineering at the University of Minnesota, where she directs the Biopreservation Core Resource and the Technological Leadership Institute, and is president-elect of the Society for Cryobiology.
Allison Hubel's Published Works
Published Works
- Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices (2014) (359)
- Cryopreservation of Human iPS Cell Aggregates in a DMSO-Free Solution—An Optimization and Comparative Study (2020) (199)
- In vitro culture characteristics of corneal epithelial, endothelial, and keratocyte cells in a native collagen matrix. (2000) (146)
- Hepatic Tissue Engineering: Development of Critical Technologies (1992) (145)
- Biomechanical and microstructural characteristics of a collagen film-based corneal stroma equivalent. (2006) (92)
- Freezing-induced phase separation and spatial microheterogeneity in protein solutions. (2009) (80)
- Parameters of cell freezing: implications for the cryopreservation of stem cells. (1997) (78)
- Cryopreservation of hematopoietic and non-hematopoietic stem cells. (2006) (73)
- A new approach to the cryopreservation of hepatocytes in a sandwich culture configuration. (1990) (70)
- Biomechanical and optical characteristics of a corneal stromal equivalent. (2003) (69)
- Long‐term storage of peripheral blood stem cells frozen and stored with a conventional liquid nitrogen technique compared with cells frozen and stored in a mechanical freezer (2010) (61)
- Response of the cell membrane-cytoskeleton complex to osmotic and freeze/thaw stresses. (2010) (59)
- Storage of human biospecimens: selection of the optimal storage temperature. (2014) (58)
- Mechanical and Cellular Changes During Compaction of a Collagen-Sponge-Based Corneal Stromal Equivalent (2004) (56)
- Preservation of stem cells (2009) (52)
- Cryopreservation of isolated hepatocytes: intracellular ice formation under various chemical and physical conditions. (1991) (52)
- Intracellular Ice Formation during the Freezing of Hepatocytes Cultured in a Double Collagen Gel (1991) (51)
- Preservation of cell-based immunotherapies for clinical trials. (2019) (47)
- Clinical mesenchymal stromal cell products undergo functional changes in response to freezing. (2015) (46)
- Spatial distribution of the state of water in frozen mammalian cells. (2010) (45)
- Water transport and IIF parameters for a connective tissue equivalent. (2006) (45)
- Cryopreservation of Hematopoietic Stem Cells: Emerging Assays, Cryoprotectant Agents, and Technology to Improve Outcomes (2019) (44)
- Survival of directionally solidified B-lymphoblasts under various crystal growth conditions. (1992) (43)
- Detection and downregulation of type I IGF receptor expression by antibody-conjugated quantum dots in breast cancer cells (2009) (39)
- Postthaw viability of precultured hepatocytes. (2001) (38)
- Liquid storage, shipment, and cryopreservation of cord blood (2004) (38)
- State of the art in preservation of fluid biospecimens. (2011) (37)
- Redefining cooling rate in terms of ice front velocity and thermal gradient: first evidence of relevance to freezing injury of lymphocytes. (1990) (36)
- Combinations of Osmolytes, Including Monosaccharides, Disaccharides, and Sugar Alcohols Act in Concert During Cryopreservation to Improve Mesenchymal Stromal Cell Survival. (2016) (36)
- OPTIMIZATION OF A MICROFLUIDIC DEVICE FOR DIFFUSION-BASED EXTRACTION OF DMSO FROM A CELL SUSPENSION. (2008) (35)
- Improved Post-Thaw Function and Epigenetic Changes in Mesenchymal Stromal Cells Cryopreserved Using Multicomponent Osmolyte Solutions. (2017) (33)
- Inducing cells to disperse nickel nanowires via integrin-mediated responses (2015) (32)
- Cell partitioning during the directional solidification of trehalose solutions. (2006) (31)
- Experimental study of diffusion-based extraction from a cell suspension (2008) (30)
- Microstructural Characteristics of Extracellular Matrix Produced by Stromal Fibroblasts (2006) (30)
- Freezing Responses in DMSO-Based Cryopreservation of Human iPS Cells: Aggregates Versus Single Cells. (2018) (30)
- Numerical characterization of diffusion-based extraction in cell-laden flow through a microfluidic channel. (2007) (30)
- Retroviral transduction and expansion of peripheral blood lymphocytes for the treatment of mucopolysaccharidosis type II, Hunter's syndrome (1999) (29)
- Short‐term liquid storage of umbilical cord blood (2003) (29)
- Immortalization and functional characterization of rat arachnoid cell lines (2011) (28)
- Influence of preculture on the prefreeze and postthaw characteristics of hepatocytes. (2000) (27)
- Freezing characteristics of isolated pig and human hepatocytes. (1997) (26)
- Modeling the interaction of biological cells with a solidifying interface (2007) (25)
- Magnetic Barcode Nanowires for Osteosarcoma Cell Control, Detection and Separation (2013) (25)
- Rapid MR imaging of cryoprotectant permeation in an engineered dermal replacement. (2000) (25)
- Cryobiophysical characteristics of genetically modified hematopoietic progenitor cells. (1999) (25)
- Characterizing Intracellular Ice Formation of Lymphoblasts Using Low-Temperature Raman Spectroscopy. (2017) (25)
- Influence of matrix processing on the optical and biomechanical properties of a corneal stroma equivalent. (2008) (25)
- Algorithm‐driven optimization of cryopreservation protocols for transfusion model cell types including Jurkat cells and mesenchymal stem cells (2017) (24)
- Interfacial Interactions of Sucrose during Cryopreservation Detected by Raman Spectroscopy. (2018) (23)
- Cryopreservation of cord blood after liquid storage. (2003) (23)
- Diffusion‐based extraction of DMSO from a cell suspension in a three stream, vertical microchannel (2012) (21)
- Advancing the preservation of cellular therapy products (2011) (20)
- Cryopreservation of Hematopoietic Stem Cells: Emerging Science, Technology and Issues (2007) (19)
- Development of an infusible-grade solution for non-cryopreserved hematopoietic cell storage. (1999) (19)
- In vitro collagen fibril alignment via incorporation of nanocrystalline cellulose. (2015) (19)
- What are the biggest challenges and opportunities for biorepositories in the next three to five years? (2010) (18)
- The characterization of arachnoid cell transport II: Paracellular transport and blood–cerebrospinal fluid barrier formation (2012) (17)
- Cryopreservation of HPCs for clinical use (2001) (16)
- Cell motion and recovery in a two-stream microfluidic device (2010) (16)
- Low temperature light microscopy and its application to study freezing in aqueous solutions and biological cell suspensions (1986) (16)
- Characterizing modes of action and interaction for multicomponent osmolyte solutions on Jurkat cells (2019) (16)
- Characterizing the “sweet spot” for the preservation of a T-cell line using osmolytes (2018) (16)
- Alignment of collagen matrices using magnetic nanowires and magnetic barcode readout using first order reversal curves (FORC) (invited) (2017) (15)
- Natural deep eutectic systems for nature-inspired cryopreservation of cells. (2020) (14)
- Isolation of fibroblasts and epithelial cells in Bronchoalveolar Lavage (BAL) (2013) (14)
- Arachnoid cells on culture plates and collagen scaffolds: phenotype and transport properties. (2011) (14)
- Thermoregulation and heat exchange in a nonuniform thermal environment during simulated extended EVA. Extravehicular activities. (2000) (14)
- Subzero osmotic characteristics of intact and disaggregated hepatocyte spheroids. (1999) (13)
- Preservation of Cells: A Practical Manual (2018) (13)
- Stabilization of tissue specimens for pathological examination and biomedical research. (2012) (11)
- Understanding the freezing responses of T cells and other subsets of human peripheral blood mononuclear cells using DSMO-free cryoprotectants. (2020) (11)
- Water Content in an Engineered Dermal Replacement during Permeation of Me2SO Solutions Using Rapid MR Imaging (2001) (10)
- Freezing Characteristics of Genetically Modified Lymphocytes for the Treatment of MPS II (1999) (10)
- Postthaw characterization of umbilical cord blood: markers of storage lesion (2015) (10)
- BLENDING TECHNOLOGY KEY TO MAKING NEW GASOLINES (1991) (9)
- Frontiers in biotransport: water transport and hydration. (2009) (8)
- Erratum: Long-term storage of peripheral blood stem cells frozen and stored with a conventional liquid nitrogen technique compared with cells frozen and stored in a mechanical freezer: (Transfusion (2010);50:808-819) (2010) (8)
- A Model Of Low‐Temperature Water Transport For Hepatocyte Spheroids a (1998) (7)
- Silica hybrid for corneal replacement: optical, biomechanical, and ex vivo biocompatibility studies. (2012) (7)
- Transient electrical potentials measured during the unidirectional freezing of NaCl/H2O solutions (1988) (6)
- Noncryopreserved Bone Marrow Storage in STM-Sav, an Infusible-Grade Cell Storage Solution (2002) (6)
- Influence of buoyancy-driven flow on mass transfer in a two-stream microfluidic channel: Introduction of cryoprotective agents into cell suspensions. (2012) (6)
- Differential Evolution for the Optimization of DMSO-free Cryoprotectants: Influence of Control Parameters. (2019) (5)
- Preservation of Cellular Therapies: Gene Therapy, Cellular, and Metabolic Engineering (2006) (4)
- Comfort and Heat Control During Extended Space Flights (1996) (4)
- Differentiation of Human iPS Cells Into Sensory Neurons Exhibits Developmental Stage-Specific Cryopreservation Challenges (2021) (4)
- Investigation of subzero water transport properties for isolated hepatocytes and hepatocytes cultured in spheroids (1995) (4)
- Transport Characteristics of Glycerol and Propylene Glycol in an Engineered Dermal Replacement (2002) (4)
- Long-term storage of gametes and gonadal tissues at room temperatures: the end of the ice age? (2022) (4)
- High-Throughput Processing to Preserve Viable Cells: A Precision Medicine Initiative Cohort Program Workshop. (2017) (3)
- Post-Thaw Function and Caspase Activity of Cryopreserved Hepatocyte Aggregates (2004) (3)
- Freezing Characteristics of Isolated Pig and Human Hepatocytes (1997) (3)
- Characterization of phase front morphologies in aqueous solutions subjected to directional solidification (1989) (3)
- Impact of Freeze–Thaw Processes on the Quality of Cells (2017) (2)
- Comparative analysis of cell therapy infusion workflows at clinical sites. (2021) (2)
- Application of transport phenomena analysis technique to cerebrospinal fluid. (2013) (2)
- Principles of Cryopreservation (2017) (2)
- Cryobiophysical parameters for freshly isolated human hepatocytes and HEP G2/C3A cells (1995) (2)
- Raman Cryomicroscopic Imaging and Sample Holder for Spectroscopic Subzero Temperature Measurements. (2020) (2)
- Mobilization and transduction of peripheral blood progenitor cells in patients with mucopolysaccharidosis I. (1998) (2)
- Influence of Matrix Processing on the Optical and Biomechanical Properties of a Corneal Stroma Equivalent (2008) (2)
- Steerable nanobots for diagnosis and therapy (2014) (1)
- Algorithm optimization of cryopreservation protocols to improve mesenchymal stem cell functionality (2016) (1)
- The influence of fibroblast on the arachnoid leptomeningeal cells in vitro (2017) (1)
- Cryopreservation of Peripheral Blood Mononuclear Cells from Whole Blood (2018) (1)
- Directional solidification for the freezing of cell suspensions (1989) (1)
- Natural deep eutectic systems for improved cryopreservation of cells (2020) (1)
- Characterizing the “sweet spot” for the preservation of a T-cell line using osmolytes (2018) (1)
- The Role of Preservation in the Variability of Regenerative Medicine Products (2019) (1)
- Biomechanical and Optical Characteristics of a Corneal (2003) (1)
- Cryopreservation of hepatocytes: Initial experience with an improved technique to maintain long-term hepatocyte function☆ (1989) (1)
- Clinical mesenchymal stem cell products experience functional changes in response to freezing (2014) (1)
- Silica-collagen hybrid artificial cornea (2013) (1)
- Standards Used in Meeting Requirements for a Model Pre-Market Approval (PMA) of a Neural Guidance Conduit (2004) (0)
- 238 - Improved post thaw function of mesenchymal stromal cells using solutions containing osmolytes (2017) (0)
- Mechanisms of Action In Cryopreservation of Induced Pluripotent Stem Cells and Ipsc-Derived Cells (2021) (0)
- Interactions Between Mechanical Forces and Phenotype for Keratocytes Cultured in a Collagen Matrix (2002) (0)
- Practical experience and results with an advanced on-line gasoline blend optimization system (1989) (0)
- Characterization of eutectic mixtures of sugars and sugar-alcohols for cryopreservation. (2022) (0)
- Endothelial cell detachment from synthetic substrate materials at 4 °C (1996) (0)
- Cryopreservation of Oocytes by Slow Freezing (2018) (0)
- Improving Natural Killer Cell Cryopreservation Using Natural Deep Eutectic Systems (2019) (0)
- Cryopreservation of cultured blood cells for use in gene therapy and immunotherapy (1997) (0)
- Abstract of papers presented at the Twenty-Fifth Annual Meeting of the Society for Cryobiology July 11–15, 1988, Aachen, West Germany Session VI—Techniques and fundamentals of cryobiologyInfluence of growth velocity and temperature gradient on the encapsulation of B lymphoblasts☆ (1988) (0)
- Role of surface modification on the culture and transduction of hematopoietic cells for gene therapy (1999) (0)
- From the Editor's Desk. (2012) (0)
- Use of Raman Microspectroscopy to Study Partioning of Molecules During Freeze-Processing of Protein Solutions (2008) (0)
- In the Days of Beginning Global Warming: Cool Is Beautiful (2007) (0)
- Cryopreservation Of Cellular Therapies Using Multicomponent Osmolyte Solutions (2019) (0)
- Diffusion Based Chemical Extraction from Cell Suspensions in Microchannels (2007) (0)
- From the Editor's Desk. (2011) (0)
- Comparison of Geometries for Diffusion-Based Extraction of Dimethyl Sulphoxide From a Cell Suspension (2008) (0)
- Author Index to Volume 32 (1984) (0)
- Cell Motion in a Two-Stream Microfluidic Channel (2009) (0)
- Characterizing cellular membrane partitioning of DMSO using low-temperature Raman spectroscopy (2023) (0)
- COMFORT AND HEAT CONTROL OF ASTRONAUTS DURING EXTENDED SPACE FLIGHTS K.......................................... (1996) (0)
- Cell-Based Reference Materials For Cryopreservation? (2019) (0)
- DMSO-free methods of preserving mesenchymal stem cells (MSCs) that retain high levels of post thaw function (2017) (0)
- Biopreservation of Cells for Use in Biotechnology and Cell Therapy (2009) (0)
- Two compartment extraction of contaminants using a microfludic device (2005) (0)
- Mechanisms Of Cryoprotection For Multicomponent Osmolyte Solutions (2019) (0)
- Acknowledgement to reviewers 1993 (2004) (0)
- Me2SO -free preservation of iPS cells and iPS-derived sensory neurons (2022) (0)
- The freezing behavior of human lymphocytes in a process of directional solidification characterized by thermal gradient and ice front velocity (1988) (0)
- ISOTHERMAL NUCLEATION STAGE AND ITS APPLICATIONS IN THE FREEZING OF BIOLOGICAL CELLS. (1987) (0)
- Understanding physiochemical changes in Jurkat cells at different layers during freezing using Raman Spectroscopy (2016) (0)
- Cryopreservation of hepatocytes. Biophysical properties and cellular response (1991) (0)
- Cryopreservation of multicellular aggregates in an Me2SO-free solution for hpsc technologies (2020) (0)
- ATP-Bio, a new center using nanomedicine to preserve biological systems (2022) (0)
- Post Thaw Processing of Red Blood Cells Using Microfluidics (2008) (0)
- 98. Diffusion-based extraction of dimethyl sulphoxide from a cell suspension (2007) (0)
- The Role of Water at Multiple Scales in Biotransport (2008) (0)
- Post-freeze thaw characteristics of collagen sponge (1995) (0)
- DIESEL BLENDING SYSTEM CUTS QUALITY GIVE-AWAYS AT RUHR REFINERY (1991) (0)
- Expansion and transduction of blood cells for gene therapy (1997) (0)
- 49. Phase separation of protein solutions during freezing: A confocal Raman microscopy study (2008) (0)
- Transient electrical potentials measured during the unidirectional freezing of NaClH2O solutions (1985) (0)
- The 2019 ISBER Americas Regional Meeting: Times They Are A Changin'-Biobanks for the Future. (2019) (0)
- Compositions et procedes de cryopreservation pour des lymphocytes circulants (2000) (0)
- 64. Determination of the intracellular thermodynamic states of cells during freezing using single-cell microspectroscopy (2011) (0)
- Influence of co-culture and soluble factors on epithelialization of a collagen matrix (2000) (0)
- Where is cold chain innovation particularly badly needed for a commercializing industry? (2019) (0)
- Cryopreservation of Biological Systems–A Confocal Raman Microscopy Study (2010) (0)
- 46. Microfluidic processing of cells for preservation (2008) (0)
- Macroscopic and Microstructural Properties of a Multilayer Corneal Replacement (2008) (0)
- Biophysics of freezing of tissue equivalents (2005) (0)
- Biotransport special issue (2009) (0)
- Oocyte Vitrification and Warming (2018) (0)
- Influence of Microstructure on the Biomechanical and Optical Properties of Corneal Stroma Equivalents (2005) (0)
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