Altaf Wani | Academic Influence

Altaf Wani's AcademicInfluence.com Rankings

Altaf Wani

Computer Science

#11553

World Rank

#12254

Historical Rank

Machine Learning

#5585

World Rank

#5659

Historical Rank

Artificial Intelligence

#6028

World Rank

#6120

Historical Rank

Database

#9230

World Rank

#9713

Historical Rank

computer-science Degrees

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Computer Science

Altaf Wani's Degrees

Masters Computer Science Stanford University
Bachelors Computer Science University of California, Berkeley

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Why Is Altaf Wani Influential?

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According to Wikipedia, Altaf A. Wani is retired a professor in the Department of Radiology and the Department of Cellular and Molecular Biology at Ohio State University . He eas a member of Molecular Carcinogenesis and Chemoprevention program of the James Cancer Hospital and Research Institute. Dr. Wani was the Director of Molecular Carcinogenesis Laboratory and conducts Basic Cancer research in the area of DNA damage and repair.

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Altaf Wani's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Thymoquinone induces apoptosis through activation of caspase‐8 and mitochondrial events in p53‐null myeloblastic leukemia HL‐60 cells (2005) (272)
DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation (2005) (181)
Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells. (2011) (172)
Cullin 4A-mediated Proteolysis of DDB2 Protein at DNA Damage Sites Regulates in Vivo Lesion Recognition by XPC* (2006) (167)
DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity. (2006) (115)
UV radiation-induced XPC translocation within chromatin is mediated by damaged-DNA binding protein, DDB2. (2004) (113)
Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway. (2009) (108)
Tumor suppressor p53 dependent recruitment of nucleotide excision repair factors XPC and TFIIH to DNA damage. (2003) (105)
Modulation of Nucleotide Excision Repair by Mammalian SWI/SNF Chromatin-remodeling Complex* (2009) (104)
Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells (2013) (103)
USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15 (2014) (101)
Ubiquitin-specific Protease 7 Regulates Nucleotide Excision Repair through Deubiquitinating XPC Protein and Preventing XPC Protein from Undergoing Ultraviolet Light-induced and VCP/p97 Protein-regulated Proteolysis* (2014) (82)
The ubiquitin–proteasome system regulates p53-mediated transcription at p21waf1 promoter (2007) (77)
Naringenin Protects HaCaT Human Keratinocytes Against UVB‐induced Apoptosis and Enhances the Removal of Cyclobutane Pyrimidine Dimers from the Genome † (2008) (75)
ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation (2011) (74)
Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair (2007) (74)
Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells. (2000) (73)
QUANTITATION OF PYRIMIDINE DIMERS BY IMMUNOSLOT BLOT FOLLOWING SUBLETHAL UV‐IRRADIATION OF HUMAN CELLS (1987) (73)
NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sites. (2013) (73)
Human SNF5/INI1, a Component of the Human SWI/SNF Chromatin Remodeling Complex, Promotes Nucleotide Excision Repair by Influencing ATM Recruitment and Downstream H2AX Phosphorylation (2009) (73)
Mdm2 Mutant Defective in Binding p300 Promotes Ubiquitination but Not Degradation of p53* (2001) (71)
USP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168* (2015) (68)
Histone modifications: crucial elements for damage response and chromatin restoration (2010) (67)
Stem cell protein Piwil2 modulates chromatin modifications upon cisplatin treatment. (2011) (65)
Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites. (2009) (65)
Decreased DNA Repair Efficiency by Loss or Disruption of p53 Function Preferentially Affects Removal of Cyclobutane Pyrimidine Dimers from Non-transcribed Strand and Slow Repair Sites in Transcribed Strand* (2000) (65)
Influence of p53 tumor suppressor protein on bias of DNA repair and apoptotic response in human cells. (1999) (64)
ANTIBODIES TO UV IRRADIATED DNA: THE MONITORING OF DNA DAMAGE BY ELISA AND INDIRECT IMMUNOFLUORESCENCE (1984) (61)
Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells (2011) (60)
DNA repair in human cells: quantitative assessment of bulky anti-BPDE-DNA adducts by non-competitive immunoassays. (1995) (59)
Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis (2010) (58)
Cellular ubiquitination and proteasomal functions positively modulate mammalian nucleotide excision repair (2005) (58)
HSP27 regulates p53 transcriptional activity in doxorubicin-treated fibroblasts and cardiac H9c2 cells: p21 upregulation and G2/M phase cell cycle arrest. (2008) (56)
USP7 modulates UV-induced PCNA monoubiquitination by regulating DNA polymerase eta stability (2014) (54)
Modulation of (±)-anti-BPDE mediated p53 accumulation by inhibitors of protein kinase C and poly(ADP-ribose) polymerase (1997) (53)
p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair (2012) (52)
Germline Stem Cell Gene PIWIL2 Mediates DNA Repair through Relaxation of Chromatin (2011) (50)
The p38 Mitogen-activated Protein Kinase Augments Nucleotide Excision Repair by Mediating DDB2 Degradation and Chromatin Relaxation* (2008) (50)
Human homologue of yeast Rad23 protein A interacts with p300/cyclic AMP-responsive element binding (CREB)-binding protein to down-regulate transcriptional activity of p53. (2001) (45)
Inhibition of Expression of the Chromatin Remodeling Gene, SNF2L, Selectively Leads to DNA Damage, Growth Inhibition, and Cancer Cell Death (2009) (45)
p53-degradation by HPV-16 E6 preferentially affects the removal of cyclobutane pyrimidine dimers from non-transcribed strand and sensitizes mammary epithelial cells to UV-irradiation. (2000) (38)
Differential DNA lesion formation and repair in heterochromatin and euchromatin. (2016) (37)
Nucleotide excision repair factor XPC enhances DNA damage-induced apoptosis by downregulating the antiapoptotic short isoform of caspase-2. (2012) (36)
Mutagenicity of Tocopheryl Quinones: Evolutionary Advantage of Selective Accumulation of Dietary a-Tocopherol (2002) (35)
ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle (2016) (34)
DDB2 modulates TGF-β signal transduction in human ovarian cancer cells by downregulating NEDD4L (2015) (33)
Dissociation of CAK from Core TFIIH Reveals a Functional Link between XP-G/CS and the TFIIH Disassembly State (2010) (31)
DNA Damage-Binding Complex Recruits HDAC1 to Repress Bcl-2 Transcription in Human Ovarian Cancer Cells (2013) (31)
Role of Claspin in regulation of nucleotide excision repair factor DDB2. (2007) (29)
Assessment of DNA damage and repair in specific genomic regions by quantitative immuno-coupled PCR. (1994) (29)
Rapid activation of apoptosis in human promyelocytic leukemic cells by (+/-)-anti-benzo[a]pyrene diol epoxide induced DNA damage. (1993) (29)
Human cells deficient in p53 regulated p21(waf1/cip1) expression exhibit normal nucleotide excision repair of UV-induced DNA damage. (2002) (29)
Thymoquinone upregulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells (2008) (28)
Damaged DNA-binding protein down-regulates epigenetic mark H3K56Ac through histone deacetylase 1 and 2. (2015) (27)
Efficient repair of bulky anti-BPDE DNA adducts from non-transcribed DNA strand requires functional p53 but not p21(waf1/cip1) and pRb. (2002) (27)
Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair (2015) (27)
In situ PYRIMIDINE DIMER DETERMINATION BY LASER CYTOMETRY (1989) (26)
Sem1p and Ubp6p orchestrate telomeric silencing by modulating histone H2B ubiquitination and H3 acetylation (2009) (25)
UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein (2016) (25)
Site-specific induction and repair of benzo[a]pyrene diol epoxide DNA damage in human H-ras protooncogene as revealed by restriction cleavage inhibition. (1996) (25)
Copper-mediated DNA damage by the neurotransmitter dopamine and L-DOPA: A pro-oxidant mechanism. (2017) (25)
Nucleotide Excision Repair: Finely Tuned Molecular Orchestra of Early Pre‐incision Events (2017) (25)
Partial purification and properties of an endonuclease from germinating pea seeds specific for single-stranded DNA. (1979) (23)
Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin* (2016) (23)
DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1 (2018) (23)
The ubiquitin‐proteasome pathway is required for the function of the viral VP16 transcriptional activation domain (2004) (22)
Modulation of transcriptional activity of p53 by ultraviolet radiation: Linkage between p53 pathway and DNA repair through damage recognition (2000) (21)
Pisum sativum endonuclease. Studies on substrate specificity and possible use as a biochemical tool. (1981) (19)
Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo. (2005) (17)
Correction: Germline Stem Cell Gene PIWIL2 Mediates DNA Repair through Relaxation of Chromatin (2011) (17)
Depleting ovarian cancer stem cells with calcitriol (2018) (17)
UV radiation-induced SUMOylation of DDB2 regulates nucleotide excision repair (2017) (16)
A sequence specific endonuclease from Micrococcus radiodurans. (1982) (15)
Caspase-2 Short Isoform Interacts with Membrane-Associated Cytoskeleton Proteins to Inhibit Apoptosis (2013) (13)
The Effect of Selective Antihypertensive drugs on the Vascular Remodeling‐associated Hypertension: Insights from a Profilin1 Transgenic Mouse Model (2011) (13)
Immunoassays for carbodiimide modified DNA-detection of unpairing transitions in supercoiled ColE1 DNA. (1989) (13)
Differential recognition of stereochemically defined base adducts by antibodies against anti-benzo[a]pyrene diol-epoxide-modified DNA. (1994) (12)
Site-specific gap-misrepair mutagenesis by O4-ethylthymine. (1987) (11)
Lack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair. (2012) (11)
A human DNA repair activity specific for O4-ethylthymine: identification and partial characterization (1990) (10)
Immunoanalysis of ultraviolet radiation induced DNA damage and repair within specific gene segments of plasmid DNA. (1991) (9)
USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced DNA damage (2019) (8)
Timely upstream events regulating nucleotide excision repair by ubiquitin-proteasome system: ubiquitin guides the way. (2021) (6)
Human CRL4DDB2 ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56Ac through recruitment of histone chaperon CAF-1 (2017) (6)
Spironolactone-induced XPB degradation requires TFIIH integrity and ubiquitin-selective segregase VCP/p97 (2020) (5)
Single-tube immuno-capture and PCR of genotoxin-modified DNA: application to gene-specific damage analysis. (1996) (4)
DDB 2 modulates TGF-signal transduction in human ovarian cancer cells by downregulating NEDD 4 L (2015) (4)
Mutational activation of H-ras oncogene transformability by alkylnitrosourea-induced DNA damage. (1992) (4)
Quantitative analysis of carbodiimide modified DNA and immunoprobing by adduct specific antibodies. (1991) (3)
Sensitizes Cisplatin-Resistant Human Ovarian Cancer Cells through Downregulation of Phosphoinositide 3-Kinase / Akt Signaling Pathway (2009) (2)
Deoxyribonuclease activity in the larvae of the army worm Spodoptera litura (1978) (2)
Abstract 3860: USP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168 (2015) (2)
Effect of dimethyl sulfate on the secondary structure of DNA (1978) (2)
Repair analysis of promutagenic (+)-anti-BPDE DNA adduct in transcriptionally active sequences of plasmid DNA in Escherichia coli. (1997) (2)
Abstract 1785: Ubiquitin specific protease 3 is a regulator of histone ubiquitination required for maintenance of genomic stability. (2013) (1)
High-throughput Phenotyping for Abiotic Stress Resilience in Cereals (2021) (1)
A nuclease specific for depurinated DNA in germinating pea seeds. (1976) (1)
Abstract 1983: Thymoquinone induces cell killing in glioblastoma cells through generation of DNA damage and cell cycle arrest (2012) (0)
Abstract 2565: VCP/p97 segregase-mediated regulation of chromatin-bound PTEN stability (2017) (0)
Abstract 2119: DDB2 and XPC influence ATR and ATM recruitment and regulate DNA damage response upon UV irradiation (2012) (0)
Studies on an endonuclease from germinating pea _pisum sativum_ seeds (1977) (0)
Abstract 4225: Thymoquinone induces cell death in glioblasotma cell through production of reactive oxygen species and induction of DNA damage (2011) (0)
Abstract 1381: Human CRL4DDB2E3 ubiquitin ligase regulates post-repair chromatin restoration of epigenetic marker H3K56Ac through recruitment of histone chaperon CAF-1 (2017) (0)
Abstract 1985: Upregulation of miR-328 contributes to ovarian cancer stem cell maintenance by downregulating DDB2 (2018) (0)
Sem 1 p and Ubp 6 p orchestrate telomeric silencing by modulating histone H 2 B ubiquitination and H 3 acetylation (2009) (0)
Biomechanical Stress in VSM Cells Leads to Vascular Remodeling and Hypertension in Profilin 1 Transgenic Mouse Model (2008) (0)
Imaging the effect of doxorubicin on GFP-expressing hair-follicle-associated blood vessels (2006) (0)
Protein to DownRegulate Transcriptional Activity of p 53 p 300 / Cyclic AMP-responsive Element Binding ( CREB )-binding Human Homologue of Yeast Rad 23 Protein A Interacts with Updated (2000) (0)
Abstract 5365: Cdt2-mediated XPG degradation promotes DNA repair synthesis following DNA damage excision in nucleotide excision repair (2014) (0)
Abstract 4893: USP7 modulates UV-induced PCNA monoubiquitylation by regulating DNA polymerase eta stability (2014) (0)
Abstract 3935: H3K56 is deacetylated in response to UV-irradiation and recovery of acetylation is regulated by ATR and ATM checkpoint kinases (2010) (0)
Regulation of p53 stability and transcriptional activity by hHR23 and its modulation by UV radiation (2000) (0)
Correction to ‘DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation’ (2021) (0)
Abstract 3946: Stem cell protein piwil2 enhances nucleotide excision repair through regulating chromatin remodeling following DNA damage (2010) (0)
Abstract 186: NER factor XPC enhances DNA damage-induced apoptosis independently of p53 function (2011) (0)
Vascular Hypertrophy‐Associated Hypertension of Profilin1 Transgenic Mouse Model led to Functional Remodeling of Vasculature (2009) (0)
Abstract 4966: The anti-apoptotic activity of caspase-2 short isoform is regulated by XPC protein (2012) (0)
Abstract B41: Thymoquinone induces-cell cycle non-specific-cell death in cisplatin-resistant ovarian cancer cell through up-regulation of PTEN expression (2012) (0)
Abstract 1999: ATR- and ATM-regulated H3K56 acetylation mediates recovery from UV-induced cell-cycle checkpoint arrest (2011) (0)
Anthocyanins (2022) (0)
Abstract 2474: DDB2 and XPC, two proteins involved in NER, influence ATM recruitment to the UV damage site and regulate downstream signaling pathway (2011) (0)
Combination of cisplatin and tangeretin induces apoptosis in cisplatin-resistant human ovarian cancer cells through modulation of phospho-Akt and its downstream substrates (2008) (0)
Chromatin-remodeling Complex by Mammalian SWI / SNF Modulation of Nucleotide Excision Repair and Chromosome Dynamics : DNA : Replication , Repair , Recombination (2009) (0)
Abstract 750: Negative regulation ofbcl-2transcription by DNA damage-binding protein complex in human ovarian cancer cells. (2013) (0)
Chromatin , Gene , and RNA Regulation DNA Damage-Binding Complex Recruits HDAC 1 to Repress Bcl-2 Transcription in Human Ovarian Cancer Cells (2014) (0)
Abstract 840: Caspase 2 short isoform interacts with membrane-associated cytoskeleton proteins to inhibit apoptosis. (2013) (0)
Functional interaction between gene transactivation, ubiquitylation and proteasome-mediated protein degradation (2002) (0)
Abstract 1786: UV damage-induced histone H3 lysine 56 deacetylation regulates nucleotide excision repair and checkpoint signaling. (2013) (0)
Abstract 1965: Cross-talk among the components of DNA damage response and chromatin remodeling (2010) (0)
Hsp27 regulates p53 transcriptional activity in ultraviolet C‐induced DNA damage of MCF‐7 cells (2009) (0)
DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1 (2018) (0)
Inununoassays for carbodiimide modified DNA-detectJon of unpairing transitions in supercoUed ColEl DNA (2005) (0)
Gene-specific repair of benzo[a]pyrene diol epoxide DNA damage in human cells (1995) (0)
Abstract 2391: USP7 deubiquitinates XPC in response to ultraviolet light irradiation (2014) (0)
Abstract 2252: Mechanism of thymoquinone-induced cell death in glioblastoma multiforme. (2013) (0)
Abstract 4784: Regulation of ovarian cancer stem cell population by DDB2 (2017) (0)
Substrate specificity of pisum sativum endo nuclease and its action on super helical dna (1980) (0)
Chapter 4 Solid Phase Immunoassay for Determining the Inosine Content in Transfer RNA (1990) (0)
Abstract 4414: Radiation-induced miR-5094 expression inhibits cell proliferation by targeting STAT5b (2018) (0)

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