Alvin Shrier
#113,379
Most Influential Person Now
Canadian scientist
Alvin Shrier's AcademicInfluence.com Rankings
Alvin Shrierengineering Degrees
Engineering
#8272
World Rank
#9784
Historical Rank
Biomedical Engineering
#846
World Rank
#859
Historical Rank
Electrical Engineering
#2609
World Rank
#2740
Historical Rank
Applied Physics
#2999
World Rank
#3064
Historical Rank

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Engineering
Alvin Shrier's Degrees
- PhD Biomedical Engineering McGill University
- Masters Biomedical Engineering McGill University
- Bachelors Electrical Engineering McGill University
Why Is Alvin Shrier Influential?
(Suggest an Edit or Addition)According to Wikipedia, Alvin Shrier is Professor in the Department of Physiology and holds the Hosmer Chair in Physiology at McGill University in Montreal, Quebec, Canada. Biography He obtained a Bachelor of Science from Concordia University, followed by a Doctor of Philosophy from Dalhousie University.
Alvin Shrier's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Phase locking, period-doubling bifurcations, and irregular dynamics in periodically stimulated cardiac cells. (1981) (503)
- Effects of experimental heart failure on atrial cellular and ionic electrophysiology. (2000) (377)
- Bifurcation and chaos in a periodically stimulated cardiac oscillator (1983) (171)
- Chaos in neurobiology (1983) (163)
- Expression of Distinct ERG Proteins in Rat, Mouse, and Human Heart (2000) (161)
- Global bifurcations of a periodically forced biological oscillator (1984) (158)
- N‐linked glycosylation sites determine HERG channel surface membrane expression (1999) (158)
- Spiral wave generation in heterogeneous excitable media. (2002) (151)
- Localization and Enhanced Current Density of the Kv4.2 Potassium Channel by Interaction with the Actin-Binding Protein Filamin (2000) (147)
- Prediction of complex atrioventricular conduction rhythms in humans with use of the atrioventricular nodal recovery curve. (1987) (140)
- Novel Mechanism for Brugada Syndrome: Defective Surface Localization of an SCN5A Mutant(R1432G) (2001) (131)
- Electrophysiological properties of morphologically distinct cells isolated from the rabbit atrioventricular node. (1996) (117)
- Differential distribution of Kir2.1 and Kir2.3 subunits in canine atrium and ventricle. (2002) (97)
- Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block (2019) (96)
- Co-chaperone FKBP38 Promotes HERG Trafficking* (2007) (91)
- Global organization of dynamics in oscillatory heterogeneous excitable media. (2005) (90)
- Heterogeneity of sodium current in atrial vs epicardial ventricular myocytes of adult guinea pig hearts. (2002) (90)
- Bursting calcium rotors in cultured cardiac myocyte monolayers. (1998) (87)
- Nonlinear dynamics, chaos and complex cardiac arrhythmias (1987) (86)
- Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization (2005) (76)
- Hsp40 Chaperones Promote Degradation of the hERG Potassium Channel* (2009) (73)
- Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium. (1999) (70)
- Phase resetting of spontaneously beating embryonic ventricular heart cell aggregates. (1986) (70)
- Phase-locked rhythms in periodically stimulated heart cell aggregates. (1988) (69)
- Characterization of potassium-dependent currents in protoplasts of corn suspension cells. (1989) (69)
- Universal Bifurcations and the Classification of Cardiac Arrhythmias a (1987) (64)
- Identification of a COOH-terminal Segment Involved in Maturation and Stability of Human Ether-a-go-go-related Gene Potassium Channels* (2003) (62)
- Interactive effects of isoprenaline, forskolin and acetylcholine on Ca2+ current in frog ventricular myocytes. (1989) (57)
- Calcineurin B Homologous Protein 3 Promotes the Biosynthetic Maturation, Cell Surface Stability, and Optimal Transport of the Na+/H+ Exchanger NHE1 Isoform* (2008) (55)
- Sodium Channel Distribution Within the Rabbit Atrioventricular Node as Analysed by Confocal Microscopy (1997) (54)
- A quantitative description of the E-4031-sensitive repolarization current in rabbit ventricular myocytes. (1995) (53)
- Single‐channel analysis of fast transient potassium currents from rat nodose neurones. (1985) (51)
- Inactivation of A currents and A channels on rat nodose neurons in culture (1989) (51)
- Predicting the onset of period-doubling bifurcations in noisy cardiac systems (2015) (51)
- Junctional resistance and action potential delay between embryonic heart cell aggregates (1980) (48)
- Paroxysmal starting and stopping of circulating waves in excitable media. (2000) (47)
- Series resistance compensation for whole-cell patch-clamp studies using a membrane state estimator. (1999) (46)
- The role of heterogeneities and intercellular coupling in wave propagation in cardiac tissue (2006) (46)
- Propagation through heterogeneous substrates in simple excitable media models. (2002) (45)
- Aldosterone, SGK1, and ion channels in the kidney (2018) (44)
- Repolarization currents in embryonic chick atrial heart cell aggregates. (1986) (44)
- Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines (2013) (42)
- High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants. (2020) (42)
- Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane (2013) (42)
- Phase resetting of the rhythmic activity of embryonic heart cell aggregates. Experiment and theory. (1984) (41)
- Bursting behavior during fixed-delay stimulation of spontaneously beating chick heart cell aggregates. (1997) (41)
- Spontaneous Initiation and Termination of Complex Rhythms in Cardiac Cell Culture (2003) (40)
- Potassium channel blockade: A mechanism for suppressing ventricular fibrillation. (1986) (39)
- hERG quality control and the long QT syndrome (2016) (36)
- Inhibition of PRL-2·CNNM3 Protein Complex Formation Decreases Breast Cancer Proliferation and Tumor Growth* (2016) (35)
- The DNAJA2 Substrate Release Mechanism Is Essential for Chaperone-mediated Folding* (2012) (34)
- Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium. (1999) (29)
- Phase resetting in a model of cardiac Purkinje fiber. (1987) (27)
- Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its α-kinase domain. (2013) (27)
- Spatial distribution of nerve processes and β‐adrenoreceptors in the rat atrioventricular node (1998) (27)
- Reentrant waves in a ring of embryonic chick ventricular cells imaged with a Ca2+ sensitive dye. (2003) (26)
- High affinity forskolin inhibition of L-type Ca2+ current in cardiac cells. (1990) (26)
- Developmental changes in subthreshold pace‐maker currents in chick embryonic heart cells. (1981) (26)
- Contribution of ATP‐sensitive potassium channels to the electrophysiological effects of adenosine in guinea‐pig atrial cells. (1995) (26)
- Analysis of subthreshold pace‐maker currents in chick embryonic heart cells. (1981) (25)
- Inhibition of metabolism abolishes transient outward current in rabbit atrial myocytes. (1994) (25)
- Pacemaker current in single cells and in aggregates of cells dissociated from the embryonic chick heart. (1992) (25)
- Ionic mechanisms and nonlinear dynamics of embryonic chick heart cell aggregates. (1994) (24)
- N-Myristoylation and Ca2+ Binding of Calcineurin B Homologous Protein CHP3 Are Required to Enhance Na+/H+ Exchanger NHE1 Half-life and Activity at the Plasma Membrane* (2012) (23)
- Effects of Divalent Cations on the E-4031-Sensitive Repolarization Current, IKr, in Rabbit Ventricular Myocytes (1998) (23)
- Stochastic and spatial influences on drug-induced bifurcations in cardiac tissue culture. (2009) (22)
- Pacemaker currents in chick embryonic heart cells change with development (1980) (22)
- Phase resetting of embryonic chick atrial heart cell aggregates. Experiment and theory. (1990) (22)
- Overdrive suppression of spontaneously beating chick heart cell aggregates: experiment and theory. (1995) (22)
- Relationship Between Different Recovery Curves Representing Rate‐Dependent AV Nodal Function in Rabbit Heart (1994) (21)
- Evolution of rhythms during periodic stimulation of embryonic chick heart cell aggregates. (1991) (21)
- Differential Responsiveness of Atrial and Ventricular Myocytes to Potassium Channel Openers (1995) (21)
- Spatial symmetry breaking determines spiral wave chirality. (2014) (21)
- On the role of subthreshold dynamics in neuronal signaling. (1999) (20)
- Bag1 Co-chaperone Promotes TRC8 E3 Ligase-dependent Degradation of Misfolded Human Ether a Go-Go-related Gene (hERG) Potassium Channels* (2016) (20)
- C-terminal Domain of Kv4.2 and Associated KChIP2 Interactions Regulate Functional Expression and Gating of Kv4.2* (2006) (19)
- Repolarization current in embryonic chick atrial heart cells. (1988) (19)
- Transient outward current contributes to Wenckebach-like rhythms in isolated rabbit ventricular cells. (1997) (18)
- Theoretical computation of phase locking in embryonic atrial heart cell aggregates. (1990) (18)
- Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7)* (2016) (18)
- Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension. (2016) (17)
- Pacemaker interactions induce reentrant wave dynamics in engineered cardiac culture. (2012) (16)
- Hsp70 and DNAJA2 limit CFTR levels through degradation (2019) (15)
- Chaotic dynamics in cardiac aggregates induced by potassium channel block. (2012) (15)
- Rhythms Produced by High‐Amplitude Periodic Stimulation of Spontaneously Beating Aggregates of Embryonic Chick Ventricular Myocytes a (1990) (15)
- Comparison of the pacemaker properties of chick embryonic atrial and ventricular heart cells (2005) (15)
- A comparative study of collagenase- and trypsin-dissociated embryonic heart cells: reaggregation, electrophysiology, and pharmacology. (1983) (15)
- The Topology of Phase Response Curves Induced by Single and Paired Stimuli in Spontaneously Oscillating Chick Heart Cell Aggregates (1992) (14)
- 11. Chaotic cardiac rhythms (1986) (13)
- KHz-rate volumetric voltage imaging of the whole Zebrafish heart (2020) (13)
- Mutation-specific peripheral and ER quality control of hERG channel cell-surface expression (2019) (12)
- New Methods for the Analysis of Heartbeat Behavior in Risk Stratification (2011) (12)
- Resetting and Annihilating Reentrant Waves in a Ring of Cardiac Tissue: Theory and Experiment (2000) (12)
- Scaling properties of conduction velocity in heterogeneous excitable media. (2011) (11)
- Action Potentials Occur Spontaneously in Squid Giant Axons with Moderately Alkaline Intracellular pH (2001) (10)
- Effects of tetrodotoxin on heart cell aggregates. Phase resetting and annihilation of activity. (1990) (10)
- Characterization of constitutive and acid-induced outwardly rectifying chloride currents in immortalized mouse distal tubular cells (2017) (10)
- Effects of divalent cations on the E-4031-sensitive repolarization current, I(Kr), in rabbit ventricular myocytes. (1998) (10)
- Varieties of reentrant dynamics. (2017) (9)
- A review of the effects of three cardioactive agents on the electrical activity from embryonic chick heart cell aggregates: TTX, ACh, and E-4031. (1994) (9)
- Low-Dimensional Dynamics in the Heart (1991) (9)
- Temperature Dependence of Bistability in Squid Giant Axons with Alkaline Intracellular pH (2002) (9)
- Demonstration of cardiac rotor and source mapping techniques in embryonic chick monolayers. (2017) (8)
- Transient Receptor Potential Melastatin 7 Cation Channel KinaseNovelty and Significance (2016) (8)
- Aldosterone and Ion Channels. (2019) (8)
- Herpes virus infection alters electrical parameters of heart cell aggregates. (1978) (7)
- Phase resetting and dynamics in isolated atrioventricular nodal cell clusters. (1995) (7)
- Complex Rhythms Resulting From Overdrive Suppression in Electrically Stimulated Heart Cell Aggregates (1990) (7)
- Global organization of dynamics in cultured cardiac monolayers. (2004) (6)
- Optical mapping of pacemaker interactions (1999) (6)
- Interactive effects of isoprenaline forskolin and acetylcholine on calcium current in single frog ventricular cells (1988) (5)
- Functional Characterization of Oscillatory and Excitable Media (2015) (4)
- Coupling dependent wavefront stability in heterogeneous cardiac cell cultures (2003) (4)
- Mechanisms of conduction time hysteresis in rabbit atrioventricular node. (1995) (4)
- Defining the pattern of initiation of monomorphic ventricular tachycardia using the beat-to-beat intervals recorded on implantable cardioverter defibrillators from the RAFT study: A computer-based algorithm. (2018) (4)
- Voltage-dependent inactivation of the potassium current of embryonic chick hepatocytes. (1991) (4)
- Double-wave reentry in excitable media. (2019) (4)
- Universal mechanisms for self-termination of rapid cardiac rhythm. (2020) (3)
- George Ralph Mines (1886–1914): the dawn of cardiac nonlinear dynamics (2016) (3)
- Hormonal and Non-Hormonal Regulation of Ca2+ Current and Adenylate Cyclase in Cardiac Cells (1990) (3)
- Transmembrane sodium current is different in atrial from ventricular myocytes of guinea pig heart (2001) (2)
- Spiral–pacemaker interactions in a mathematical model of excitable medium (2013) (2)
- Pattern of initiation of monomorphic ventricular tachycardia and implications on tachycardia mechanism. (2017) (2)
- LETTERS TO THE EDITOR: Control of Membrane Potential in Double Sucrose Gap Voltage Clamp Technique (1977) (2)
- Subcellular localization of the Na 1 / H 1 exchanger NHE 1 in rat myocardium (1999) (1)
- Classification and recovery properties of isolated atriventricular node cells (1992) (1)
- Correction of hERG Functional Expression and Defective Peripheral Processing in Inherited and Acquired LQT2 Syndromes (2020) (1)
- The Challenge of Complex Dynamics for Theoretical Models of Cardiac Activity (1997) (1)
- Effects of D-600 on sodium current in squid axons (2005) (1)
- Transient Receptor Potential Melastatin 7 Cation Channel (TRPM7) Kinase: a new player in Ang II-induced hypertension (2016) (1)
- C-terminal Domain of Kv4.2 and Associated KChIP2 Interactions Regulate Functional Expression (2006) (0)
- Molecular and cellular characterization of the myocardial Na+/H+ exchanger (1998) (0)
- Characterization ofPotassium-Dependent Currents in Protoplasts ofCornSuspension Cells1 (1989) (0)
- Functional Characterization of Oscillatory and Excitable Media (2014) (0)
- Unidirectional Block Demonstrated on Ventricular Monolayers Expressing Channelrhodopsin-2 using Optogenetics (2020) (0)
- Historical note on the untimely passing of George Ralph Mines (2016) (0)
- Rhythms from Two Competing Periodic Sources Embedded in an Excitable Medium. (2023) (0)
- Aldosterone regulates the TRPM7 chanzyme (2012) (0)
- Reduced Cell Surface Stability Of Rescued Herg Trafficking Mutants (2009) (0)
- Predicting discrete-time bifurcations with deep learning (2023) (0)
- BURSTING IN CELLULAR AUTOMATA AND CARDIAC ARRHYTHMIAS (2013) (0)
- Ionic current analysis of phase resetting in embryonic heart cell aggregates (1983) (0)
- hERG Quality Control at the Plasma Membrane (2012) (0)
- Effects of tetrodotoxin on heart cell aggregates (2005) (0)
- Predicting the Onset of Alternating Rhythms in Noisy Cardiac Systems (2016) (0)
- Bag 1 promotes TRC 8-dependent degradation of misfolded hERG potassium channels (2016) (0)
- UNIVERSAL PATTERNS OF CARDIAC ACTIVITY (2004) (0)
- The Effects of Noise in Biological Excitable Media (2019) (0)
- Mutation-specific peripheral and ER quality control of hERG channel cell-surface expression (2019) (0)
- Acid-Induced Chloride Current in Distal Convoluted Tubule (2016) (0)
- hERG Trafficking is Dependent on a Cytosolic Chaperone Network (2009) (0)
- Binding of Syntaxin 1A to the C-terminus of hERG Channels Affects Channel Trafficking and Inactivation (2009) (0)
- Optogenetic Control of Re-Entrant Waves Demonstrated in Human Induced Stem Cell Derived Cardiomyocytes (hiPSC-CMs) (2019) (0)
- Author response: Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block (2019) (0)
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