Alvin Williams Nienow

Alvin Williams Nienow's AcademicInfluence.com Rankings

Engineering

#4307

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#5497

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Applied Physics

#1019

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#1044

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Engineering

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Alvin Williams Nienow's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mixing in the process industries (1985) (445)
Physiological responses to mixing in large scale bioreactors. (2001) (429)
Reactor Engineering in Large Scale Animal Cell Culture (2006) (373)
On impeller circulation and mixing effectiveness in the turbulent flow regime (1997) (280)
Suspension of solid particles in turbine agitated baffled vessels (1968) (244)
Hydrodynamics of Stirred Bioreactors (1998) (236)
The translation of cell-based therapies: clinical landscape and manufacturing challenges. (2015) (233)
Mixing in large-scale vessels stirred with multiple radial or radial and axial up-pumping impellers: modelling and measurements (2000) (184)
On the Sauter mean diameter and size distributions in turbulent liquid/liquid dispersions in a stirred vessel (1998) (178)
Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor (2013) (177)
The dependency on scale of power numbers of Rushton disc turbines (1987) (163)
The minimum fluidisation velocity, bed expansion and pressure-drop profile of binary particle mixtures (1979) (162)
The effects of agitation intensity with and without continuous sparging on the growth and antibody production of hybridoma cells (1989) (153)
Expansion of human mesenchymal stem cells on microcarriers (2011) (148)
The scale-up of microbial batch and fed-batch fermentation processes. (2007) (145)
Scale-down model to simulate spatial pH variations in large-scale bioreactors. (2001) (145)
CAVERN SIZES IN AGITATED FLUIDS WITH A YIELD STRESS (1981) (143)
A potentially scalable method for the harvesting of hMSCs from microcarriers (2014) (134)
Use of angle resolved PIV to estimate local specific energy dissipation rates for up- and down-pumping pitched blade agitators in a stirred tank (2009) (128)
Particle-gas-liquid mixing in stirred vessels. I: Particle-liquid mixing (1983) (123)
X-ray studies of cavern sizes and mixing performance with fluids possessing a yield stress (1986) (121)
CFD Study of Homogenization with Dual Rushton Turbines—Comparison with Experimental Results: Part I: Initial Studies☆ (2000) (120)
Bubble Sizes in Electrolyte and Alcohol Solutions in a Turbulent Stirred Vessel (1997) (119)
Gas–liquid dispersion with dual Rushton impellers (1989) (118)
Video technique for measuring dynamics of liquid‐liquid dispersion during phase inversion (1994) (115)
The influence of impeller type on mean drop size and drop size distribution in an agitated vessel (1999) (114)
Macro- and micromixing studies in an unbaffled vessel agitated by a Rushton turbine (2008) (112)
Agitators for mycelial fermentations (1990) (111)
Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors (2016) (108)
The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4 (2013) (107)
CFD Study of Homogenization with Dual Rushton Turbines—Comparison with Experimental Results: Part II: The Multiple Reference Frame☆ (2000) (103)
Aspects of mixing in rheologically complex fluids (1988) (97)
Suspension and Liquid Homogenization in High Solids Concentration Stirred Chemical Reactors (1999) (96)
Control of pH in large-scale, free suspension animal cell bioreactors: alkali addition and pH excursions. (1999) (95)
Gas-liquid mixing studies : A comparison of Rushton turbines with some modern impellers (1996) (93)
Particle growth mechanisms in fluidised bed granulation—I: The effect of process variables (1983) (92)
Parameter estimation for a solids mixing|segregation model for gas fluidised beds (1982) (91)
A new mathematical model to predict cavern diameters in highly shear thinning, power law liquids using axial flow impellers (1998) (91)
Further studies of the culture of mouse hybridomas in an agitated bioreactor with and without continuous sparging. (1992) (89)
Particle suspension in the turbulent regime: The effect of impeller type and impeller/vessel configuration (1996) (88)
Mixing of Highly Viscous Simulated Xanthan Fermentation Broths with the Lightnin A‐315 Impeller (1992) (87)
Mixing in the Fermentation and Cell Culture Industries (2004) (87)
An LDA study of the turbulent flow field in a baffled vessel agitated by an axial, down-pumping hydrofoil impeller (1996) (86)
Homogenisation and oxygen transfer rates in large agitated and sparged animal cell bioreactors: Some implications for growth and production (2004) (86)
STUDIES OF SEGREGATION/MIXING IN FLUIDISED BEDS OF DIFFERENT SIZE PARTICLES (1987) (84)
Effects of agitation and scale-up on drop size in turbulent dispersions: allowance for intermittency (2001) (81)
Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: beyond the T flask. (2012) (81)
Further studies related to the scale‐up of high cell density escherichia coli fed‐batch fermentations: (2003) (80)
Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum‐free microcarrier process (2015) (80)
Scale-down studies for assessing the impact of different stress parameters on growth and product quality during animal cell culture (2013) (80)
POWER, GAS DISPERSION AND HOMOGENISATION CHARACTERISTICS OF SCABA SRGT AND RUSHTON TURBINE IMPELLERS (1992) (78)
Fluidisation of fine and very dense hardmetal powders (1990) (78)
Physiological and environmental factors affecting the growth of insect cells and infection with baculovirus. (1995) (78)
Chapter 16 – The suspension of solid particles (1992) (77)
Fluidised binary mixtures in which the denser component may be flotsam (1980) (77)
Power curves and flow patterns for a range of impellers in newtonian fluids: 40 (1995) (75)
THE EFFECT OF SIZE, LOCATION AND PUMPING DIRECTION OF PITCHED BLADE TURBINE IMPELLERS ON FLOW PATTERNS: LDA MEASUREMENTS AND CFD PREDICTIONS (2001) (74)
Small bubble formation via a coalescence dependent break-up mechanism (2003) (74)
Gas—liquid mixing studies with multiple up‐ and down‐pumping hydrofoil impellers: Power characteristics and mixing time (1998) (71)
Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development (2016) (71)
On the structure of turbulent liquid—liquid dispersed flows in an agitated vessel (1994) (69)
Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms (2016) (68)
An LDA study of turbulent flow in a baffled vessel agitated by a pitched blade turbine (1991) (67)
Positron emission particle tracking (PEPT) compared to particle image velocimetry (PIV) for studying the flow generated by a pitched-blade turbine in single phase and multi-phase systems (2009) (66)
Gas dispersion performance in fermenter operation (1990) (65)
Effect of ion excess on particle size and morphology during barium sulphate precipitation: an experimental study (2001) (64)
Blending of Miscible Liquids (2004) (63)
Mixing studies in a model aerated bioreactor equipped with an up-or a down-pumping 'Elephant Ear' agitator : Power, hold-up and aerated flow field measurements (2009) (63)
CFD modelling of continuous precipitation of barium sulphate in a stirred tank (2003) (63)
Particle abrasion at high solids concentration in stirred vessels - II (1978) (62)
Impeller Power Numbers in Closed Vessels (1971) (62)
Performance of the scaba 6SRGT agitator in mixing of simulated xanthan gum broths (1993) (61)
The Influence of the Addition Position of a Tracer on CFD Simulated Mixing Times in a Vessel Agitated by a Rushton Turbine (2002) (61)
Study Of Micromixing in a Stirred Tank Using a Rushton Turbine: Comparison of Feed Positions and Other Mixing Devices (2002) (61)
PEPT measurements of solid–liquid flow field and spatial phase distribution in concentrated monodisperse stirred suspensions (2010) (61)
Suspension of microcarriers for cell culture with axial flow impellers (2004) (60)
A comparison of high cell density fed‐batch fermentations involving both induced and non‐induced recombinant Escherichia coli under well‐mixed small‐scale and simulated poorly mixed large‐scale conditions (2007) (60)
Study of drop and bubble sizes in a simulated mycelial fermentation broth of up to four phases. (2000) (60)
Power drawn by multiple impellers in sparged agitated vessels (1979) (60)
Inter-particle forces that suppress bubbling in gas fluidised beds (1971) (59)
Power numbers, Taylor numbers and Taylor vortices in viscous newtonian and non-newtonian fluids (1986) (59)
An LDA study of the radial discharge velocities generated by a Rushton turbine : Newtonian fluids, Re ≥ 5 (1993) (58)
The application of multi-parameter flow cytometry to the study of recombinant Escherichia coli batch fermentation processes (2004) (56)
Studies on three-phase mixing: a review and recent results (1986) (56)
Minimum fluidisation velocity of multi-component particle mixtures (1975) (55)
Catalytic conversion of sodium lignosulfonate to vanillin: Engineering aspects. part 1. effects of processing conditions on vanillin yield and selectivity (2013) (52)
Intensifying micromixing in a semi-batch reactor using a Rushton turbine (2005) (52)
Cavern Sizes Generated in Highly Shear Thinning Viscous Fluids by SCABA 3SHP1 Impellers (1997) (50)
Positron emission particle tracking in a mechanically agitated solid–liquid suspension of coarse particles (2009) (50)
The effect of impeller/tank, configurations on fluid-particle mass transfer (1978) (50)
Using positron emission particle tracking (PEPT) to study the turbulent flow in a baffled vessel agitated by a Rushton turbine: Improving data treatment and validation (2011) (49)
Visualisation of bubble coalescence in a coalescence cell, a stirred tank and a bubble column (1998) (49)
Large-scale osmotic priming of onion seeds: a comparison of different strategies for oxygenation (1991) (49)
Recent Studies on Agitated Three-Phase (Gas–Solid–Liquid) Systems in the Turbulent Regime (2002) (48)
THE EFFECT OF RHEOLOGICAL COMPLEXITIES ON POWER CONSUMPTION IN AN AERATED, AGITATED VESSEL (1983) (46)
Agitated vessel particle-liquid mass transfer: A comparison between theories and data (1975) (46)
Operational intensification by direct product sequestration from cell disruptates: application of a pellicular adsorbent in a mechanically integrated disruption-fluidised bed adsorption process. (2002) (46)
BUBBLE SIZES AND COALESCENCE RATES IN AN AERATED VESSEL AGITATED BY A RUSHTON TURBINE (1993) (45)
FLUIDISED BED GRANULATION AND COATING: APPLICATIONS TO MATERIALS, AGRICULTURE AND BIOTECHNOLOGY (1995) (43)
A MULTIPURPOSE STIRRED TANK FACILITY FOR FLOW VISUALISATION AND DUAL IMPELLER POWER MEASUREMENT (1983) (43)
Break-up, coalescence and catastrophic phase inversion in turbulent contactors. (2004) (43)
Predicting the tangential velocity field in stirred tanks using the Multiple Reference Frames (MRF) model with validation by LDA measurements (2000) (41)
Stirring and Stirred‐Tank Reactors (2014) (40)
Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 1. Review (1995) (40)
Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production. (2015) (37)
Flow over disc turbine blades (1974) (37)
Shannon entropy for local and global description of mixing by Lagrangian particle tracking (2010) (36)
Enhancing Xanthan Fermentations by Different Modes of Glucose Feeding (1998) (36)
On atomising a liquid into a gas fluidised bed (1982) (36)
The versatility of up-pumping hydrofoil agitators (2004) (34)
Bubble Size Distributions in Impeller Region in a Gas-Sparged Vessel Agitated by a Rushton Turbine (1992) (33)
Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate. (2016) (33)
Chapter 17 – The mixer as a reactor: liquid/solid systems (1992) (31)
Process development of human multipotent stromal cell microcarrier culture using an automated high‐throughput microbioreactor (2017) (31)
Delayed phase inversion in stirred liquid—liquid dispersions (1989) (31)
Fabrication by three-phase emulsification of pellicular adsorbents customised for liquid fluidised bed adsorption of bioproducts (2003) (31)
Establishing the large scale osmotic priming of onion seeds by using enriched air (1989) (31)
The use of upward pumping 45° pitched blade turbine impellers in three-phase reactors (1990) (31)
The impact of fluid mechanical stress on Corynebacterium glutamicum during continuous cultivation in an agitated bioreactor (2005) (30)
Scale-up of stirring as foam disruption (SAFD) to industrial scale (2003) (30)
A study of an up‐ and a down‐pumping wide blade hydrofoil impeller: Part I. LDA measurements (1998) (30)
Gas-liquid dispersion with dual Rushton turbine impellers. (1989) (30)
Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 4. Comparison of Impeller Types (1996) (30)
Mass Transfer and Mixing Across the Scales in Animal Cell Culture (2015) (30)
Mixing in a Model Bioreactor Using Agitators with a High Solidity Ratio and Deep Blades (2007) (30)
Bubble sizes in agitated air-alcohol systems with and without particles : Turbulent and transitional flow (2005) (30)
Studies on the Effect of Mechanical Agitation on the Performance of Brewing Fermentations: Fermentation Rate, Yeast Physiology, and Development of Flavor Compounds (2002) (29)
A dynamometer for the accurate measurement of mixing torque (1969) (29)
CFD modelling of turbulent drop breakage in a kenics static mixer and comparison with experimental data (2007) (29)
Mixing in the Process Industries: Second Edition (1997) (29)
The Impact of Fluid Mechanical Stress on Saccharomyces Cerevisiae Cells During Continuous Cultivation in an Agitated, Aerated Bioreactor; its Implication for Mixing in the Brewing Process and Aerobic Fermentations (2003) (28)
Impeller Selection for Animal Cell Culture (2010) (28)
Scale‐up of mixing in gassed multi‐turbine agitated vessels (1998) (28)
Alternative Ways of Applying the Hydrogen Peroxide Steady State Method of KLa Measurement (1997) (27)
Attrition of urea in a gas-fluidised bed (1986) (26)
Scale-up agitation criteria for Trichoderma reesei fermentation (2017) (26)
Comparing a range of impellers for "stirring as foam disruption" (2002) (26)
Oxygen Transfer in Stirred Bioreactors Under Animal Cell Culture Conditions (2002) (26)
The effects of the azimuthal position of the measurement plane on the flow parameters determined by PIV within a stirred vessel (2010) (25)
A quantitative approach for understanding small-scale human mesenchymal stem cell culture - implications for large-scale bioprocess development. (2013) (24)
MASS TRANSFER AND HOLD-UP CHARACTERISTICS IN A GASSED, STIRRED VESSEL AT INTENSIFIED OPERATING CONDITIONS (2001) (24)
Stirred Tank Reactors (2010) (24)
Some effects of pseudoplasticity on hold-up in aerated, agitated vessels (1980) (24)
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds. (2020) (23)
Scale‐Up, Stirred Tank Reactors (2010) (23)
A new pair of reactions to characterize imperfect macro-mixing and partial segregation in a stirred semi-batch reactor (1992) (23)
Estimation of Cavern Sizes in a Shear-Thinning Plastic Fluid Agitated by a Rushton Turbine Based on LDA Measurements (1994) (23)
The Transition from Homogeneous to Heterogeneous Flow in a Gassed, Stirred Vessel (2000) (22)
Bioreactor Engineering Fundamentals for Stem Cell Manufacturing (2016) (22)
Chapter 1 – Introduction to mixing problems (1992) (22)
The Effect of Shape on the Mixing and Segregation of Large Particles in a Gas-Fluidised Bed of Small Ones (1980) (22)
Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development (2018) (22)
The effect of sodium caseinate concentration and processing conditions on bubble sizes and their break-up and coalescence in turbulent, batch air/aqueous dispersions at atmospheric and elevated pressures (2003) (22)
The effect of volume fraction and impeller speed on the structure and drop size in aqueous/aqueous dispersions (2001) (22)
Sliding mesh computational fluid dynamics—a predictive tool in stirred tank design (1997) (22)
Scale-Up Considerations Based on Studies at the Bench Scale in Stirred Bioreactors (2009) (21)
Micromixing in two‐phase (G‐L and S‐L) systems in a stirred vessel (2011) (21)
On flow close to cavern boundaries in yield stress fluids (1994) (20)
Bioprocess development for scalable production of cultivated meat (2020) (20)
Measurement of Drop Size Distribution in Concentrated Liquid-Liquid Dispersions - Video and Capillary Techniques (1995) (20)
A problem for the description of turbulent dispersed liquid-liquid systems (1995) (20)
An Extension to the Incorporation Model of Micromixing and Its Use in Estimating Local Specific Energy Dissipation Rates (2008) (20)
The effect of storage on the germination and seedling abnormalities of leek seeds primed and dried by different methods (1994) (20)
Scale‐down/scale‐up studies leading to improved commercial beer fermentation (2011) (19)
Comparison of polyethylene glycol polymers, betaine and L-preoline for priming vegetable seed (1991) (19)
Lagrangian tools for the analysis of mixing in single‐phase and multiphase flow systems (2012) (19)
Fabrication and characterisation of a novel pellicular adsorbent customised for the effective fluidised bed adsorption of protein products (2001) (19)
Expansion of bone marrow‐derived human mesenchymal stem/stromal cells (hMSCs) using a two‐phase liquid/liquid system (2017) (19)
Mixing of dense binary suspensions: Multi-component hydrodynamics and spatial phase distribution by PEPT (2011) (19)
Using Positron Emission Particle Tracking (PEPT) to Study Mixing in Stirred Vessels: Validation and Tackling Unsolved Problems in Opaque Systems (2009) (18)
Particle growth mechanisms in fluidised bed granulation—II: Comparison of experimental data with growth models (1983) (18)
The Effect of Bottom Roughness on the Minimum Agitator Speed Required to Just Fully Suspend Particles in a Stirred Vessel (2007) (18)
A fluid dynamic study using a simulated viscous, shear thinning broth of the retrofitting of large agitated bioreactors (2000) (18)
Fed-batch bioconversion of indene to cis-indandiol (2002) (18)
Intervortex mixing rates in high-viscosity liquids agitated by high-speed dual impellers (1986) (18)
Bubble sizes in agitated solvent/reactant mixtures used in heterogeneous catalytic hydrogenation of 2-butyne-1,4-diol (2006) (17)
Strategies for control of seed-borne Alternaria dauci (leaf blight) of carrots in priming and process engineering systems (1992) (17)
Establishing the scalable manufacture of primary human T‐cells in an automated stirred‐tank bioreactor (2019) (17)
Simultaneous measurement of in situ bubble size and reaction rates with a heterogeneous catalytic hydrogenation reaction (2007) (17)
Measurement of gas and liquid flows in stirred tank reactors with multiple agitators (2009) (16)
Diffusion Coefficients of Potassium Sulfate in Water. (1964) (16)
Studies supporting the use of mechanical mixing in large scale beer fermentations (2010) (16)
A study of an up- and a down-pumping wide-blade hydrofoil impeller : Part II. CFD analysis (1998) (16)
A Novel Measurement Technique for Mixing Time in an Aerated Stirred Vessel (2003) (16)
Liquid Homogenization Studies in Animal Cell Bioreactors of up to 8 m3 in Volume (1998) (15)
A Process for the Manufacture of Chemically Produced Toner (CPT). I. Evolution of Structure and Rheology (2005) (15)
The effect of viscosity on mixing pattern and solid suspension in stirred vessels (1994) (15)
Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing (2019) (14)
Demonstrating the Manufacture of Human CAR‐T Cells in an Automated Stirred‐Tank Bioreactor (2020) (14)
Expansion of human mesenchymal stem/stromal cells on temporary liquid microcarriers (2020) (14)
A Process for the Manufacture of Chemically Produced Toner (CPT). II. Effect of Operating Conditions (2005) (14)
Effect of Gas Density on Power Consumption in Aerated Vessel Agitated by a Rushton Turbine (1992) (14)
Bubble Sizes in Agitated Water−Hydrophilic Organic Solvents for Heterogeneous Catalytic Reactions (2007) (13)
The characteristics of aerated 12- and 18-blade Rushton turbines at transitional Reynolds numbers (1995) (13)
3rd International Conference on Bioreactor and Bioprocess Fluid Dynamics (1993) (13)
Advanced digital image analysis method dedicated to the characterization of the morphology of filamentous fungus (2017) (13)
Comparison of Experimental Techniques for the Measurement of Mixing Time in Gas‐Liquid Systems (2001) (13)
The Impact of Fluid Dynamic Stress in Stirred Bioreactors – The Scale of the Biological Entity: A Personal View (2020) (12)
Generation of Hydrogen Gas during the Catalytic Oxidation of Sodium Lignosulfonate to Vanillin: Initial Results (2012) (12)
The mass transfer driving force for high mass flux (1969) (12)
A stirred tank for continuous crystallization studies (1982) (11)
Improving Xanthan Fermentation Performance by Changing Agitators (1992) (11)
Slip velocities in agitated vessel crystallisers (1972) (10)
Phase separation and drop size distributions in “homogeneous” Na-alginate/Na-caseinate mixtures (2000) (10)
Mixing studies related to the cleaning of molten aluminium (2004) (10)
Physical conditions during batch culture of hybridomas in laboratory scale stirred tank reactors. (1985) (10)
Scale‐down studies for the scale‐up of a recombinant Corynebacterium glutamicum fed‐batch fermentation: loss of homogeneity leads to lower levels of cadaverine production (2019) (10)
Engineering considerations on the use of liquid/liquid two phase systems as a cell culture platform (2017) (10)
Gas Dispersion Characteristics of Newly Developed Impellers in a Stirred Vessel (2003) (10)
Bulk priming and drying of leek seeds : the effects of two polymers of polyethylene glycol and fluidised bed drying (1991) (10)
Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applications (2021) (9)
A study of uninfected and baculovirus-infected Spodoptera frugiperda cells in T- and spinner flasks (2004) (9)
Mixing Time for Different Diameters of Impeller at a High Solid Concentration in an Agitated Vessel (2005) (9)
VORTEX CAVITY SHAPE AND THE ASSOCIATED PATH-LINE OF DISCHARGED BUBBLES IN AN AERATED VESSEL AGITATED BY A RUSHTON TURBINE (1992) (9)
Scale‐up of an intensified bioprocess for the expansion of bovine adipose‐derived stem cells (bASCs) in stirred tank bioreactors (2021) (9)
Fluidized bed granulation technology and its application to tungsten carbide (1986) (8)
Some Effects of Particle Wettability in Agitated Solid-Gas-Liquid Systems: Gas-Liquid Mass Transfer and the Dispersion of Floating Solids (2008) (8)
Mixing of Three-Phase Systems at High Solids Content (up to 40% w/w) Using Radial and Mixed Flow Impellers (2001) (8)
An Experimental Study To Characterize Imperfect Macromixing in a Stirred Semibatch Reactor (1997) (8)
Priming responses of leek (Allium porrum L.) seeds to different dissolved oxygen levels in the osmoticum (1993) (8)
Aeration in Biotechnology (2015) (8)
Scale-up studies for osmotic priming and drying of carrot seeds (1991) (7)
Further Studies of Micromixing: Scale-Up, Baffling and Feed Pipe Backmixing (2011) (7)
The effects of re-use of polyethylene glycol priming osmotica upon the development of microbial populations and germination of leeks and carrots (1991) (7)
RHEOLOGICAL CHARACTERISTICS,POWER CONSUMPTION,MASS AND HEAT,TRANSFER DURING XANTHAN GUM FERMENTATION (1994) (7)
Mixing by rotary jet heads: Indications of the benefits of head rotation under turbulent and transitional flow conditions (2008) (7)
The interaction of yield stress and viscoelasticity on the Weissenberg effect (1982) (7)
Scalable Manufacture for Cell Therapy Needs (2016) (6)
Barium Sulphate Precipitation in a double-feed semi-batch stirred reactor (2003) (6)
The Use of Phase Inversion Temperature (PIT) Microemulsion Technology to Enhance Oil Utilisation during Streptomyces rimosus Fed-batch Fermentations to Produce Oxytetracycline (2005) (6)
PARTICLE GROWTH MECHANISM IN FLUIDIZED BED GRANULATION (1983) (6)
Quantitative Measurements of the Critical Impeller Speed for Solid‐Liquid Suspensions (2019) (6)
The role of biopreservation in cell and gene therapy bioprocessing (2017) (6)
Assessment of the Effects of Agitation on Mashing for Beer Production in a Small Scale Vessel (2003) (6)
Studies on the Impact of Mixing in Brewing Fermentation: Comparison of Methods of Effecting Enhanced Liquid Circulation (2003) (6)
On the effect of liquid height on the flooding/loading transition (1987) (6)
Oil/water and pre-emulsified oil/water (PIT) dispersions in a stirred vessel: Implications for fermentations. (2003) (6)
An application of jet grinding to fluidised bed granulation (1991) (5)
The behaviour of segregating fluidized beds and its relevance to ash management (1989) (5)
A Strategy for Solving a Mathematical Model of Barium Sulphate Precipitation in a Continuous Stirred Tank Reactor (2004) (5)
Evolution of drop size distributions and average drop diameter in liquid-liquid dispersions before and after phase inversion (1993) (5)
Hydrodynamics of a shear thinning fluid in a tank with axial flow impellers (1993) (5)
Instabilities when using a standard (T/3) Rushton turbine for stirring as foam disruption (SAFD) (2000) (5)
The bulk priming of leek seeds —the influence of oxygen-enriched air (1991) (5)
Power Input and Gas Hold up in Gas Liquid Dispersions Agitated by Axial Flow Impellers (1992) (4)
Corrigendum to ‘‘Use of angle resolved PIV to estimate local specific energy dissipation rates for up- and down-pumping pitched blade agitators in a stirred tank” [Chem. Eng. Sci. 64 (2009) 126–143] (2009) (4)
A mathematical model for agitation-induced fragmentation of (1997) (4)
Design and Performance of Single-Use, Stirred-Tank Bioreactors (2016) (4)
The Scale-up of Human Mesenchymal Stem Cell Expansion and Recovery (2016) (4)
A TECHNIQUE FOR STUDYING INTERVORTEX MIXING RATES IN A DUAL IMPELLER AGITATED VESSEL IN HIGH VISCOSITY FLUIDS (1984) (4)
Constant turnover time as a scale-up criterion for agitated tanks (1974) (4)
The impact of fine particles and their wettability on the coalescence of sunflower oil drops in water (2000) (3)
The use of emulsification technologies to enhance rapeseed oil consumption during industrial Streptomyces rimosus fed-batch fermentations (2007) (3)
Studies of an independently-driven, dual impeller protofermenter with and without a draft tube: power and hold-up (1996) (3)
Consideration of mixing at the pilot plant stage in bioreactors (2005) (3)
The impact of fluid-dynamic stress in stirred tank bioreactors on the synthesis of cellulases by Trichoderma reesei at the intracellular and extracellular levels (2020) (2)
The kinetics of mixing: stretching, chaos and transport,: J.M. Ottino Cambridge University Press, 1989, 364 pp. (1991) (2)
The Performance of a Proto-Fermenter Containing Independently-Driven Dual Impellers in a Draft Tube (IDDIDT): Mixing Times (1998) (2)
Gassed Power Consumption and Gas Hold-up for a Dual Hollow Blade Impeller System in a Stirred Vessel (2003) (2)
Stirred Bioreactor Engineering for Production Scale, Low Viscosity Aerobic Fermentations: Part 2 (2012) (2)
Comparison of Traditional Rushton Disc Turbines with Up-pumping Hydrofoil B2 Impellers in 550 L Pilot Scale Aerobic Submerged Fermentations (2009) (2)
Sliding Mesh Simulation of Transitional, Non-Newtonian Flow in a Baffled, Stirred Tank (1996) (2)
Comment on : Gas recirculation rate and its influences on mass transfer in multiple impeller systems with various impeller combinations (2003) (2)
Effect of formaldehyde on hold‐up in aerated, stirred tanks (1979) (2)
Needle to needle robot‐assisted manufacture of cell therapy products (2022) (2)
Concentration-Dependent Physical Properties and Rates of Mass Transport (1966) (1)
Moving jets mix up the food and drink industry (2010) (1)
Engineering research on mixing: State of the art introductory remarks (1998) (1)
Impact of fine particles and their wettability on coalescence and phase inversion in sunflower oil + water systems (2003) (1)
CFD analysis involving liquid aluminium in-furnace cleaning process (2003) (1)
Isolation and expansion of human bone marrow-derived mesenchymal stem cells (hMSCs) directly on microcarriers in a stirred tank bioreactor (2019) (1)
The Use of Multi-parameter Flow Cytometry for Characterisation of Insect Cell-baculovirus Cultures (2007) (1)
Priming of seeds - scaling up for commercial use (1993) (1)
Phase Inversion Behaviour of Aqueous Two-Phase Systems (1992) (1)
CHAPTER 8 – Fluidized bed granulation (1983) (1)
Process development of human mesenchymal stem cell microcarrier culture using an automated high-throughput microbioreactor (2017) (1)
Basic Biotechnology: Insect and mammalian cell culture (2006) (1)
Mixing: Studies at the University of Birmingham on This Traditional Technology Critical in the Manufacture of New Biological Products (2000) (1)
POWER AND HOLD-UP IN THE MIXING OF AERATED HIGHLY VISCOUS NON-NEWTONIAN FLUIDS (1981) (1)
Fluid-bed heat transfer : By J. S. M. Botterill, published by Academic Press, London, 1975; Price £9.00. (1976) (0)
Experimental and computational fluid dynamics studies of adherent cells on microcarriers in an ambr® 250 bioreactor (2018) (0)
A liquid/liquid two phase system as an economic alternative for the large-scale expansion of bone marrow-derived human mesenchymal stem/stromal cells (hMSCs) (2017) (0)
Bioprocess Scale-Up Strategy based on Integration of Fluid Dynamics and Microbial Physiology (1998) (0)
Stirred, not shaken: tales from an academic mixer (2004) (0)
Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: (2017) (0)
Scaleup and design of industrial mixing processes. By Gary B. Tatterson, McGraw Hill, New York, 312 pp., 1994 $56 (1995) (0)
Adaptation to Stirred Culture - A Study of a Moderately Shear Sensitive Cell Line (PQXB1/2). (1993) (0)
Identification of fluid dynamic stress response of T. reesei during continuous fermentations conducted at high agitation rate (2017) (0)
PC-Based On-Line Estimation of Derived Variables (1989) (0)
Agitation strategies for the culture and detachment of human mesenchymal stem cells (hMSCs) from microcarriers in multiple bioreactor platforms (2016) (0)
Influence of the Shape of Small Reaction Vessels on Liquid Phase Synthesis of Silica Particles (2009) (0)
The larger scale expansion of pluripotent stem cells for regenerative medicine purposes (2012) (0)
Experimental and Computational Fluid Dynamics study of microcarrier suspension during the cultivation of Mesenchymal Stem Cells in an ambr250 bioreactor (2017) (0)
BIOSYNTHETIC RESPONSES AND SCANNING ELECTRON MICROSCOPIC STUDIES OF MURINE HYBRIDOMAS SUBJECTED TO HYDRODYNAMIC STRESSES (1994) (0)
Bioreaction engineering Vol. 2: Characteristics features of bioreactors: by Karl Schügerl, John Wiley & Sons, 1991. £95.00 (xxiv + 393 pages) ISBN 0 471 91309 X (1992) (0)
THE APPLICATION OF MIXING THEORY TO THE SCALEUP OF STEM CELL CULTURE (2014) (0)
Fluid Dynamic Studies of A Large Bioreactor with Different Cooling Coil Geometries (2000) (0)
Mixing: A traditional technology critical in the production of new biological products (1999) (0)
ECB12: 12th European Congess on Biotechnology (2005) (0)
Mixing bowl cell lysates. (2000) (0)
Perfluorocarbons: potential for successful expansion of bone marrow-derived human mesenchymal stem cells in a liquid/liquid two phase system (2016) (0)
The scale-up of microbial batch and fed-batch fermentation processes (2007) (0)
CFD analysis of power numbers and velocity in an industrial scale bioreactor scale bioreactor-comparison with experimental results (2003) (0)
Break-up and Coalescence of Bubbles in Agitated Protein Solutions at High Air Volume Fraction (2005) (0)
Recent Studies on Stirred Bioreactors at the SERC Centre for Biochemical Engineering at Birmingham (1994) (0)
Studies of Aerated Mixing with Multiple Axial Flow Hydrofoil (APV-B2) Impellers (2000) (0)
Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor (2013) (0)
MICROMIXING IN TWO- AND THREE-PHASE (S-L AND G-S-L) SYSTEMS IN A STIRRED VESSEL (2012) (0)
Metabolic and biosynthetic responses of hybridomas subjected to hydrodynamic stress (2007) (0)
Characterization of a single-use stirred-tank bioreactor vessel for microcarrier-based adherent cell culture processes using experimental and computational fluid dynamics studies (2017) (0)
Book ReviewIndustrial Mixing Fundamentals with Applications, G.B. Tatterson, R.V. Calabrese, W.R. Penny (Eds.), AIChE (1995), p. 179, $105, ISBN: 0 8169 0668 8 (1997) (0)
FACTORS AFFECTING GROWTH, INFECTION AND PROTEIN YIELD IN BACULOVIRUS -INFECTED INSECT CELLS (1994) (0)
AUTOMATED APPROACHES FOR PROCESS DEVELOPMENT AND MANUFACTURE OF HUMAN MESENCHYMAL STEM CELLS FOR CELL-BASED THERAPIES (2017) (0)
Stirring; Theory and Practice, Zlokarnik Marko. Published by Wiley-VCH (2001), p.362, ISBN: 3 527 29996 3 (2002) (0)
THE INSTITUTION OF CHEMICAL ENGINEERS' WORKING PARTY ON THE MIXING OF POWDERS, PASTES AND NON-NEWTONIAN FLUIDS (1972) (0)
Foreword: ISMIP, 1995 to 2020, THE International Mixing Conference (2018) (0)
Basic bioreactor design: Bioreactors in Biotechnology: A Practical Approach edited by A. J. Scragg, Ellis Harwood, 1991. UK£59.00 (330 pages) ISBN 0 13 085143 4 (1993) (0)
Professor Christopher Julian Hewitt FREng 1969–2019 (2019) (0)
Application of the migratory nature of human mesenchymal stem cells to optimise microcarrier-based expansion processes (2017) (0)

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