Amar J. S. Klar
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Amar J. S. Klarbiology Degrees
Biology
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#14223
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Developmental Biology
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#149
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Genetics
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#1265
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Molecular Biology
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#1648
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Biology
Amar J. S. Klar's Degrees
- PhD Molecular Biology University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Amar J. S. Klar Influential?
(Suggest an Edit or Addition)Amar J. S. Klar's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. (1991) (3480)
- Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus (1982) (368)
- Four mating‐type genes control sexual differentiation in the fission yeast. (1988) (347)
- Cloning and characterization of four SIR genes of Saccharomyces cerevisiae (1986) (306)
- A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae (1983) (280)
- Chromosomal Inheritance of Epigenetic States in Fission Yeast During Mitosis and Meiosis (1996) (231)
- MAR1-a Regulator of the HMa and HMalpha Loci in SACCHAROMYCES CEREVISIAE. (1979) (220)
- Transposable mating type genes in Saccharomyces cerevisiae (1979) (215)
- Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast. (1998) (204)
- Statistical modeling and analysis of the LAGLIDADG family of site-specific endonucleases and identification of an intein that encodes a site-specific endonuclease of the HNH family. (1997) (201)
- Active genes in budding yeast display enhanced in vivo accessibility to foreign DNA methylases: a novel in vivo probe for chromatin structure of yeast. (1992) (184)
- A Chromodomain Protein, Swi6, Performs Imprinting Functions in Fission Yeast during Mitosis and Meiosis (2000) (181)
- Regulation of transcription in expressed and unexpressed mating type cassettes of yeast (1981) (178)
- The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast (1998) (175)
- Regulation of mating-type information in yeast. Negative control requiring sequences both 5' and 3' to the regulated region. (1984) (175)
- A recombinationally repressed region between mat2 and mat3 loci shares homology to centromeric repeats and regulates directionality of mating-type switching in fission yeast. (1997) (170)
- swi1 and swi3 Perform Imprinting, Pausing, and Termination of DNA Replication in S. pombe (2000) (159)
- Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast (1987) (145)
- Genes required for initiation and resolution steps of mating-type switching in fission yeast. (1984) (145)
- Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome. (1983) (142)
- Orientation of DNA replication establishes mating-type switching pattern in S. pombe (1999) (138)
- The Histone Deacetylase Genes HDA1 andRPD3 Play Distinct Roles in Regulation of High-Frequency Phenotypic Switching in Candida albicans (2001) (133)
- Rearrangements of the transposable mating‐type cassettes of fission yeast. (1984) (132)
- Three additional linkage groups that repress transcription and meiotic recombination in the mating-type region of Schizosaccharomyces pombe. (1994) (130)
- A DNA replication-arrest site RTS1 regulates imprinting by determining the direction of replication at mat1 in S. pombe. (2001) (124)
- The clr1 locus regulates the expression of the cryptic mating-type loci of fission yeast. (1992) (114)
- Cell Type Regulates Selective Segregation of Mouse Chromosome 7 DNA Strands in Mitosis (2006) (114)
- Directionality of yeast mating-type interconversion (1982) (112)
- Lessons learned from studies of fission yeast mating-type switching and silencing. (2007) (105)
- Genetic models for handedness, brain lateralization, schizophrenia, and manic-depression (1999) (101)
- A novel switch‐activating site (SAS1) and its cognate binding factor (SAP1) required for efficient mat1 switching in Schizosaccharomyces pombe. (1991) (101)
- A position-effect control for gene transposition: State of expression of yeast mating-type genes affects their ability to switch (1981) (100)
- The developmental fate of fission yeast cells is determined by the pattern of inheritance of parental and grandparental DNA strands. (1990) (99)
- The Clr7 and Clr8 Directionality Factors and the Pcu4 Cullin Mediate Heterochromatin Formation in the Fission Yeast Schizosaccharomyces pombe (2005) (99)
- Human handedness and scalp hair-whorl direction develop from a common genetic mechanism. (2003) (98)
- Initiation of meiotic recombination by double-strand DNA breaks in S. pombe (1986) (96)
- A role for DNA polymerase α in epigenetic control of transcriptional silencing in fission yeast (2001) (95)
- Involvement of double-strand chromosomal breaks for mating-type switching in Saccharomyces cerevisiae. (1984) (89)
- A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. (2001) (88)
- Extinction of Oct-3/4 gene expression in embryonal carcinoma x fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure, and transcriptional activity of the Oct-3/4 upstream region (1993) (84)
- Double-strand breaks can initiate meiotic recombination in S. cerevisiae (1986) (81)
- Left-Right Dynein Motor Implicated in Selective Chromatid Segregation in Mouse Cells (2007) (80)
- A model for specification of the left-right axis in vertebrates. (1994) (78)
- Directionality of fission yeast mating-type interconversion is controlled by the location of the donor loci. (1993) (77)
- Resolution of recombination intermediates generated during yeast mating type switching (1984) (70)
- A single locus, RGHT, specifies preference for hand utilization in humans. (1996) (68)
- DNA polymerase-α is essential for mating-type switching in fission yeast (1993) (67)
- swi6, a gene required for mating-type switching, prohibits meiotic recombination in the mat2-mat3 "cold spot" of fission yeast. (1991) (63)
- Does S. pombe exploit the intrinsic asymmetry of DNA synthesis to imprint daughter cells for mating-type switching? (2001) (58)
- Propagating epigenetic states through meiosis: where Mendel's gene is more than a DNA moiety. (1998) (57)
- Psychiatric epigenetics: a new focus for the new century (2000) (57)
- Proteinase activities of Saccharomyces cerevisiae during sporulation (1975) (56)
- Activation of mating type genes by transposition in Saccharomyces cerevisiae. (1979) (49)
- SUM1, an apparent positive regulator of the cryptic mating-type loci in Saccharomyces cerevisiae. (1985) (48)
- Switching of a mating-type a mutant allele in budding yeast Saccharomyces cerevisiae. (1979) (45)
- Sites required for position-effect regulation of mating-type information in yeast. (1983) (45)
- Developmental Pathways in Yeast (1984) (44)
- Rtf1-Mediated Eukaryotic Site-Specific Replication Termination (2008) (44)
- Evidence for a physical interaction between the transposed and the substituted sequences during mating type gene transposition in yeast (1980) (43)
- A Unique DNA Recombination Mechanism of the Mating/Cell-type Switching of Fission Yeasts: a Review. (2014) (41)
- A Genetic Mechanism Implicates Chromosome 11 in Schizophrenia and Bipolar Diseases (2004) (41)
- A Novel Function of the DNA Repair Gene rhp6 in Mating-Type Silencing by Chromatin Remodeling in Fission Yeast (1998) (39)
- Developmental choices in mating-type interconversion in fission yeast. (1992) (39)
- A role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast. (2001) (37)
- Sap1, a protein that binds to sequences required for mating-type switching, is essential for viability in Schizosaccharomyces pombe (1994) (37)
- Support for the selective chromatid segregation hypothesis advanced for the mechanism of left-right body axis development in mice. (2008) (36)
- The mechanism of fission yeast mating type interconversion: seal/replicate/cleave model of replication across the double-stranded break site at mat1. (1991) (34)
- Excess of counterclockwise scalp hair-whorl rotation in homosexual men (2004) (32)
- The Action of Homothallism Genes in Saccharomyces Diploids during Vegetative Growth and the Equivalence of hma and HMalpha Loci Functions. (1977) (32)
- The 2.1-kb inverted repeat DNA sequences flank the mat2,3 silent region in two species of Schizosaccharomyces and are involved in epigenetic silencing in Schizosaccharomyces pombe. (2002) (32)
- Map positions of yeast genes SIR1, SIR3 and SIR4. (1985) (30)
- Discovery of the mitotic selective chromatid segregation phenomenon and its implications for vertebrate development. (2010) (30)
- Biochemical Interactions between Proteins and mat1 cis-Acting Sequences Required for Imprinting in Fission Yeast (2004) (30)
- Interconversion of yeast cell types by transposable genes. (1980) (30)
- Plant mathematics: Fibonacci's flowers (2002) (29)
- Schizosaccharomyces pombe Switches Mating Type by the Synthesis-Dependent Strand-Annealing Mechanism (2007) (29)
- An epigenetic hypothesis for human brain laterality, handedness, and psychosis development. (2004) (29)
- Defining the Epigenetic Mechanism of Asymmetric Cell Division of Schizosaccharomyces japonicus Yeast (2013) (29)
- The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders. (2002) (28)
- Studies on the positive regulatory gene, GAL4, in regulation of galactose catabolic enzymes in Saccharomyces cerevisiae (1974) (28)
- The mechanism of fission yeast mating-type interconversion: evidence for two types of epigenetically inherited chromosomal imprinted events. (1993) (28)
- A 1927 Study Supports a Current Genetic Model for Inheritance of Human Scalp Hair-Whorl Orientation and Hand-Use Preference Traits (2005) (27)
- Left-right symmetry breaking in mice by left-right dynein may occur via a biased chromatid segregation mechanism, without directly involving the Nodal gene (2012) (27)
- The Yeast Mating-Type Switching Mechanism: A Memoir (2010) (26)
- The sum1-1 mutation affects silent mating-type gene transcription in Saccharomyces cerevisiae (1990) (26)
- Introduction to provocative questions in left–right asymmetry (2016) (25)
- Precise mapping of the homothallism genes HML and HMR in Saccharomyces cerevisiae. (1980) (24)
- Multiple epigenetic events regulate mating-type switching of fission yeast. (2007) (23)
- Efficient production of a ring derivative of chromosome III by the mating-type switching mechanism in Saccharomyces cerevisiae (1983) (23)
- Mutations in deoxyribonucleotide biosynthesis pathway cause spreading of silencing across heterochromatic barriers at the mating‐type region of the fission yeast (2008) (22)
- Fibonacci's flowers. (2002) (22)
- Breast cancer predisposition and brain hemispheric laterality specification likely share a common genetic cause. (2011) (22)
- Mating-Type Functions for Meiosis and Sporulation in Yeast Act through Cytoplasm. (1980) (21)
- Schizosaccharomyces japonicus Yeast Poised to Become a Favorite Experimental Organism for Eukaryotic Research (2013) (21)
- 13 Molecular Genetics of Fission Yeast Cell Type: Mating Type and Mating-type Interconversion (1992) (19)
- Determination of the yeast cell lineage (1987) (19)
- Glycan Alteration Imparts Cellular Resistance to a Membrane-Lytic Anticancer Peptide. (2017) (18)
- Effect of GAL4 Gene Dosage on the Level of Galactose Catabolic Enzymes in Saccharomyces cerevisiae (1976) (17)
- Lineage-dependent mating-type transposition in fission and budding yeast. (1993) (16)
- Going in the Right Direction: Mating-Type Switching of Schizosaccharomyces pombe Is Controlled by Judicious Expression of Two Different swi2 Transcripts (2012) (15)
- Structure of the SAD mutation and the location of control sites at silent mating type genes in Saccharomyces cerevisiae (1984) (15)
- Cloning by complementation in yeast: the mating type genes (1982) (14)
- Gene conversion of the mating-type locus in Saccharomyces cerevisiae. (1979) (13)
- Regulation of fission yeast mating-type interconversion by chromosome imprinting. (1990) (13)
- A CO-FISH assay to assess sister chromatid segregation patterns in mitosis of mouse embryonic stem cells (2013) (12)
- Irregular transpositions of mating-type genes in yeast. (1981) (12)
- The mother-daughter mating type switching asymmetry of budding yeast is not conferred by the segregation of parental HO gene DNA strands. (1987) (11)
- Selective Chromatid Segregation Mechanism Invoked For the Human Congenital Mirror Hand Movement Disorder Development by RAD51 Mutations: A Hypothesis (2014) (10)
- DNA sequence of the mat2,3 region of Schizosaccharomyces kambucha shares high homology with the corresponding sequence from Sz. pombe (2003) (10)
- Can Bronchoscopic Airway Anatomy Be an Indicator of Autism? (2011) (10)
- Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter (2017) (10)
- 2 Differentiated Parental DNA Chain Causes Stem Cell Pattern of Cell-type Switching in Schizosaccharomyces pombe (2001) (8)
- Split hand/foot malformation genetics supports the chromosome 7 copy segregation mechanism for human limb development (2016) (7)
- Extragenic suppressors of mar2(sir3) mutations in Saccharomyces cerevisiae. (1990) (7)
- A proposal for re-defining the way the aetiology of schizophrenia and bipolar human psychiatric diseases is investigated (2010) (6)
- Scalp hair-whorl orientation of Japanese individuals is random; hence, the trait's distribution is not genetically determined. (2009) (6)
- Selective chromatid segregation mechanism proposed for the human split hand/foot malformation development by chromosome 2 translocations: A perspective. (2015) (6)
- Role of Cdc23/Mcm10 in generating the ribonucleotide imprint at the mat1 locus in fission yeast (2019) (6)
- Selective Chromatid Segregation Mechanism Explains the Etiology of Chromosome 11 Translocation-Associated Psychotic Disorders: A Review (2014) (5)
- Mechanisms of Yeast Recombination (1986) (5)
- A Hypothesis for How Chromosome 11 Translocations Cause Psychiatric Disorders (2007) (4)
- Unbiased segregation of fission yeast chromosome 2 strands to daughter cells (2013) (4)
- Response to Comment on "Cell Type Regulates Selective Segregation of Mouse Chromosome 7 DNA Strands in Mitosis" (2006) (4)
- Two-dimensional agarose gel electrophoresis of restriction-digested genomic DNA (1991) (4)
- Control of enzyme synthesis and stability during sporulation in Saccharomyces cerevisiae. (1976) (3)
- Response to “Commentary on Klar” (2004) (3)
- Control of Mating Type in Yeast (1979) (2)
- Response to Millar et al. Critique of Chromosome 1;11 Translocation Causing Psychosis (2003) (2)
- Awesome, in brief (2007) (2)
- Models for the distribution of distance of specific chromosome regions in interphase nuclei (1984) (2)
- Asymmetric cell division via DNA strand-specific epigenetic imprinting and segregation explains eukaryotic development (2013) (1)
- Mating-Type Genes and Their Switching in Yeasts (2013) (1)
- Remarkably High Rate of DNA Amplification Promoted by the Mating-Type Switching Mechanism in Schizosaccharomyces pombe (2012) (1)
- The Programme of Cell Type Determination in Fission Yeast (1992) (1)
- Sex in budding yeast: How and Why (1985) (1)
- Implication of the Strand-Specific Imprinting and Segregation Model: Integrating in utero Hormone Exposure, Stem Cell and Lateral Asymmetry Hypotheses in Breast Cancer Aetiology (2013) (1)
- The developmental fate of fission yeast cells is determined by the pattern of inheritance of parental and grandparental DNA strands (1989) (0)
- Recombination at the DNA level : abstracts of papers presented at the XLIX Cold Spring Harbor Symposium on Quantitative Biology, May 30-June 6, 1984 (1984) (0)
- Unbiased segregation of fission yeast chromosome 2 strands to daughter cells (2013) (0)
- Abstracts of papers presented at the 1988 Meeting on Intermediates in Genetic Recombination, August 31-September 4, 1988 (1988) (0)
- Activation of the cmos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome ( cellular oneogene / endogenous retroviruses / transposition / repetitive cellular elements ) (1999) (0)
- Abstracts of papers presented at the 1987 Meeting on Yeast Cell Biology, August 11-August 16, 1987 (1987) (0)
- Sister chromatid differentiation/selective segregation mechanism supported for vertebrate body laterality development (2014) (0)
- Effect ofGAL4GeneDosage ontheLevel ofGalactose Catabolic EnzymesinSaccharomyces cerevisiae (1976) (0)
- Strand segregation or recombination (1987) (0)
- CRYPTIC MATING-TYPE LOCI IN SACCHAROMYCES (1985) (0)
- Asymmetric cell division via DNA strand-specific epigenetic imprinting and segregation explains eukaryotic development (2013) (0)
- Table of Contents (1990) (0)
- THE STRUCTURE OF TRANSPOSABLE MATING TYPE GENES IN YEAST (1980) (0)
- Cdc23/Mcm10 Primase Generates the Lagging Strand-Specific Ribonucleotide Imprint in Fission Yeast (2018) (0)
- Control of Mating Type in Yeast Saccharomyces (1979) (0)
- Structure oftheSADMutation andtheLocation ofControl Sites at Silent Mating TypeGenesinSaccharomyces cerevisiae (1984) (0)
- Selective chromatid segregation mechanism explains chr11 translocation causing psychoses with 50% penetrance Brain hemispheres laterality-generating cell (2014) (0)
- Selective chromatid segregation mechanism for Bruchus wings piebald color. (2015) (0)
- Rearrangement and Activation of a Cellular Oncogene (1984) (0)
- Faculty Opinions recommendation of Chiral blastomere arrangement dictates zygotic left-right asymmetry pathway in snails. (2010) (0)
- Initiation and Resolution of Mating Type Switching in Yeast (1984) (0)
- A CO-FISH assay to assess sister chromatid segregation patterns in mitosis of mouse embryonic stem cells (2013) (0)
- Genetics and Epigenetics of Human Diseases Non-Mendelian Genetics in Humans By Harry Ostrer New York: Oxford University Press (1998). 202 pp. $39.95 (1999) (0)
- genes in Saccharomyces cerevisiae. location of control sites at silent mating type Structure of the SAD mutation and the (2013) (0)
- Mechanism of Mating Type Cassette Switching (1983) (0)
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Amar J. S. Klar is affiliated with the following schools:
