Amnon Altman
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Amnon Altman's Degrees
- PhD Computer Science Stanford University
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(Suggest an Edit or Addition)Amnon Altman's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor (1992) (514)
- Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2 (1981) (309)
- Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines. (1983) (306)
- Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells. (1993) (306)
- NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. (2000) (295)
- Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes (1996) (278)
- Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation. (1993) (265)
- Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells (2001) (253)
- Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon. (1983) (250)
- PROTEIN KINASE C IN T CELL ACTIVATION (2002) (244)
- Antigen-induced translocation of PKC-θ to membrane rafts is required for T cell activation (2001) (236)
- Protein Kinase C-θ Phosphorylation of Moesin in the Actin-binding Sequence* (1998) (227)
- PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcRγ to induce slow leukocyte rolling (2008) (203)
- Inhibition of the c-Jun N-terminal Kinase/AP-1 and NF-κB Pathways by PICOT, a Novel Protein Kinase C-interacting Protein with a Thioredoxin Homology Domain* (2000) (198)
- HYPERTONIC SALINE RESUSCITATION: A TOOL TO MODULATE IMMUNE FUNCTION IN TRAUMA PATIENTS? (1997) (196)
- Macrophage activation: priming activity from a T-cell hybridoma is attributable to interferon-gamma. (1983) (185)
- T‐Lymphocyte Activation: The Role of Protein Kinase C and the Bifurcating Inositol Phospholipid Signal Transduction Pathway (1987) (182)
- Protein kinase C theta (PKCθ) : A key player in T cell life and death (2007) (167)
- Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function (1996) (158)
- Protein kinase C(theta) in T cell activation. (2002) (158)
- Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death. (1999) (148)
- Protein kinase Cθ: a new essential superstar on the T-cell stage (2000) (146)
- Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the Ras signaling pathway. (1994) (146)
- Translocation of PKCθ in T cells is mediated by a nonconventional, PI3-K– and Vav-dependent pathway, but does not absolutely require phospholipase C (2002) (145)
- Serine Phosphorylation of Cbl Induced by Phorbol Ester Enhances Its Association with 14-3-3 Proteins in T Cells via a Novel Serine-rich 14-3-3-binding Motif* (1997) (144)
- Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides (1994) (142)
- Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells. (1995) (139)
- Differential Regulation of Th2 and Th1 Lung Inflammatory Responses by Protein Kinase Cθ1 (2004) (137)
- Mechanism of Diacylglycerol-induced Membrane Targeting and Activation of Protein Kinase Cθ* (2004) (135)
- Chemical proteomic map of dimethyl fumarate–sensitive cysteines in primary human T cells (2016) (133)
- A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28 (2011) (129)
- Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment. (2006) (129)
- NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-θ (2000) (129)
- Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells. (1993) (127)
- Coordinated Regulation of the Tyrosine Phosphorylation of Cbl by Fyn and Syk Tyrosine Kinases* (1998) (127)
- Regulation of Protein Kinase Cθ Function during T Cell Activation by Lck-mediated Tyrosine Phosphorylation* (2000) (124)
- Activation-modulated Association of 14–3–3 Proteins with Cbl in T Cells* (1996) (119)
- Protein kinase Cθ, a selective upstream regulator of JNK/SAPK and IL‐2 promoter activation in Jurkat T cells (1999) (116)
- Pleiotropic defects in TCR signaling in a Vav‐1‐null Jurkat T‐cell line (2002) (112)
- Impaired activation and localization of LAT in anergic T cells as a consequence of a selective palmitoylation defect. (2006) (110)
- Protein Kinase C-η Controls CTLA-4-Mediated Regulatory T Cell Function (2014) (107)
- A Single Amino Acid Alteration in Cytoplasmic Domain Determines IL-2 Promoter Activation by Ligation of CD28 but Not Inducible Costimulator (ICOS) (2003) (107)
- Faculty Opinions recommendation of The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. (2010) (107)
- Direct cloning of human neuroblastoma cells in soft agar culture. (1980) (102)
- Protein Kinase C μ Is Negatively Regulated by 14-3-3 Signal Transduction Proteins* (1999) (101)
- Interleukin 2 mediates the inhibition of oligodendrocyte progenitor cell proliferation in vitro. (1986) (98)
- Activation of p56lck by p72syk through physical association and N-terminal tyrosine phosphorylation (1994) (98)
- SPAK kinase is a substrate and target of PKCθ in T‐cell receptor‐induced AP‐1 activation pathway (2004) (98)
- Protein kinase C‐θ (PKCθ): it's all about location, location, location (2003) (97)
- Specific high-affinity binding and biologic action of retinoic acid in human neuroblastoma cell lines. (1983) (93)
- Cbl: complex formation and functional implications. (1998) (92)
- Protein Kinase Cθ Controls Th1 Cells in Experimental Autoimmune Encephalomyelitis1 (2005) (92)
- Expression and biochemical characterization of human protein kinase C-theta. (1994) (90)
- Filamin A Is Required for T Cell Activation Mediated by Protein Kinase C-θ1 (2006) (86)
- Protein kinase C theta (PKCtheta): a key player in T cell life and death. (2007) (85)
- SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells. (2003) (84)
- Suppression of T lymphocyte function by measles virus is due to cell cycle arrest in G1. (1988) (84)
- The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor. (2005) (82)
- Vav-Rac1-Mediated Activation of the c-Jun N-Terminal Kinase/c-Jun/AP-1 Pathway Plays a Major Role in Stimulation of the Distal NFAT Site in the Interleukin-2 Gene Promoter (2001) (81)
- PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors (2012) (80)
- Protein Kinase C-θ Mediates a Selective T Cell Survival Signal Via Phosphorylation of BAD1 (2001) (76)
- Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein (1994) (73)
- Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation (1999) (72)
- Regulation of the p70zap tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase (1995) (72)
- Immunomodifiers in vaccines. (1989) (71)
- Positive feedback regulation of PLCγ1/Ca2+ signaling by PKCθ in restimulated T cells via a Tec kinase‐dependent pathway (2004) (69)
- Production of interleukin 2 (IL 2) by salivary gland lymphocytes in Sjögren's syndrome. Detection of reactive cells by using antibody directed to synthetic peptides of IL 2. (1985) (65)
- Clustering of T Cell Ligands on Artificial APC Membranes Influences T Cell Activation and Protein Kinase C θ Translocation to the T Cell Plasma Membrane1 (2005) (65)
- Protein kinase Ctheta: a new essential superstar on the T-cell stage. (2000) (64)
- Membrane lipid microdomains and the role of PKCθ in T cell activation (2001) (63)
- Ordered Just So: Lipid Rafts and Lymphocyte Function (2002) (62)
- Vav modulation of the Ras / MEK / ERK signaling pathway plays a role in NFAT activation and CD69 up‐regulation (2000) (61)
- Vav1 Promotes T Cell Cycle Progression by Linking TCR/CD28 Costimulation to FOXO1 and p27kip1 Expression1 (2006) (61)
- Ras-dependent, Ca2+-stimulated Activation of Nuclear Factor of Activated T Cells by a Constitutively Active Cbl Mutant in T Cells* (1997) (60)
- A role for PKCθ in outside‐in αIIbβ3 signaling (2006) (60)
- Tyrosine phosphorylation and activation of Vav GTP/GDP exchange activity in antigen receptor-triggered B cells. (1994) (59)
- Protein Kinase C-θ Is an Early Survival Factor Required for Differentiation of Effector CD8+ T Cells1 (2005) (57)
- New Perspectives on PKCθ, a Member of the Novel Subfamily of Protein Kinase C (1998) (57)
- Protein Kinase Cθ (PKCθ): A Key Enzyme in T Cell Life and Death (2002) (56)
- Itk Controls the Spatiotemporal Organization of T Cell Activation (2011) (55)
- Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice. (2005) (54)
- Engagement of Protein Kinase C-θ in Interferon Signaling in T-cells* (2004) (52)
- The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression. (2013) (51)
- Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells (2011) (50)
- Cell‐free media of mixed lymphocyte cultures augmenting sensitization in vitro of mouse T lymphocytes against allogeneic fibroblasts (1975) (50)
- Identification of the Site in the Syk Protein Tyrosine Kinase That Binds the SH2 Domain of Lck* (1996) (50)
- TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation (2015) (50)
- Role for Protein Kinase Cθ (PKCθ) in TCR/CD28-mediated Signaling through the Canonical but Not the Non-canonical Pathway for NF-κB Activation* (2005) (50)
- Palmitoylation-Dependent Plasma Membrane Transport but Lipid Raft-Independent Signaling by Linker for Activation of T Cells1 (2009) (48)
- Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. (2008) (47)
- Identification of a T cell hybridoma that produces large quantities of macrophage-activating factor (1982) (47)
- SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling. (2007) (47)
- A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1 (2016) (46)
- Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by Fc epsilon RI cross-linking. (1994) (46)
- NFκB–Pim-1–Eomesodermin axis is critical for maintaining CD8 T-cell memory quality (2017) (45)
- Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis. (2005) (43)
- A direct interaction between the adaptor protein Cbl-b and the kinase Zap-70 induces a positive signal in T cells (1999) (43)
- Membrane Localization and Function of Vav3 in T Cells Depend on Its Association with the Adapter SLP-76* (2005) (42)
- Protein kinase C activation inhibits tyrosine phosphorylation of Cbl and its recruitment of Src homology 2 domain-containing proteins. (1999) (41)
- Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD. (2001) (40)
- Immunogenic targeting of recombinant peptide vaccines to human antigen-presenting cells by chimeric anti-HLA-DR and anti-surface immunoglobulin D antibody Fab fragments in vitro (1995) (39)
- Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis (2019) (39)
- Perspectives on PKCtheta in T cell activation. (2004) (38)
- Faculty Opinions recommendation of Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance. (2010) (38)
- Natural cell-mediated cytotoxicity in guinea pigs: properties and specificity of natural killer cells. (1978) (37)
- Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy. (2011) (36)
- SLAT/Def6 Plays a Critical Role in the Development of Th17 Cell-Mediated Experimental Autoimmune Encephalomyelitis1 (2009) (35)
- Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias. (2002) (35)
- TCR antagonist peptides induce formation of APC‐T cell conjugates and activate a Rac signaling pathway (2000) (34)
- Protein Kinase C Enzymes in the Hematopoietic and Immune Systems. (2016) (34)
- PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretion. (2009) (34)
- PKCδ Acts Upstream of SPAK in the Activation of NKCC1 by Hyperosmotic Stress in Human Airway Epithelial Cells* (2008) (34)
- Antibodies of predetermined specificity against chemically synthesized peptides of human interleukin 2. (1984) (34)
- SWAP‐70‐like adapter of T cells: a novel Lck‐regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cells (2009) (33)
- The Induction of Autoreactive T Lymphocytes by Allogeneic Effect Factor (AEF): Relevance to Normal Pathways of Lymphocyte Differentiation (1980) (33)
- Normal T-cell receptors for alloantigens. (1973) (33)
- Vav: Function and Regulation in Hematopoietic Cell Signaling (1996) (31)
- A role for PKCtheta in outside-in alpha(IIb)beta3 signaling. (2006) (31)
- Protein Kinase Cθ C2 Domain Is a Phosphotyrosine Binding Module That Plays a Key Role in Its Activation* (2012) (31)
- Vav2 Activates c-fos Serum Response Element and CD69 Expression but Negatively Regulates Nuclear Factor of Activated T Cells and Interleukin-2 Gene Activation in T Lymphocyte* (2001) (30)
- Guanine Exchange-Dependent and -Independent Effects of Vav1 on Integrin-Induced T Cell Spreading1 2 (2003) (30)
- Protein kinase C inhibitors for immune disorders. (2014) (28)
- The biology of monoclonal lymphokines secreted by T cell lines and hybridomas. (1982) (28)
- Production and isolation of helper and suppressor factors. (1980) (28)
- Engagement of protein kinase C-theta in interferon signaling in T-cells. (2004) (27)
- Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells. (2005) (27)
- Protein kinase Ctheta, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells. (1999) (27)
- Lipid Raft Targeting of Hematopoietic Protein Tyrosine Phosphatase by Protein Kinase C θ-Mediated Phosphorylation (2006) (26)
- In and out of the bull's eye: protein kinase Cs in the immunological synapse. (2013) (26)
- TNFR-Associated Factor 6 Regulates TCR Signaling via Interaction with and Modification of LAT Adapter (2013) (25)
- Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death. (2002) (25)
- Existence of T cells manifesting self-reactivity indistinguishable from alloreactivity. (1980) (24)
- Vav‐induced activation of the human IFN‐γ gene promoter is mediated by upregulation of AP‐1 activity (2002) (24)
- Guanine Exchange-Dependent and -Independent Effects of Vav1 on Integrin-Induced T Cell Spreading (2003) (23)
- Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway. (2004) (23)
- Construction of T cell hybridomas secreting allogeneic effect factor (1980) (23)
- Improved specificity of RT-PCR amplifications using nested cDNA primers. (1993) (23)
- An efficient expression, purification and immunodetection system for recombinant gene products. (1994) (23)
- A novel motif in the V3 domain of PKC-θ determines its immunological synapse localization and functions in T cells via association with CD28 (2011) (23)
- Jun Kinase Phosphorylates and Regulates the DNA Binding Activity of an Octamer Binding Protein, T-Cell Factor β1 (1999) (23)
- Dual Regulation of T Cell Receptor-mediated Signaling by Oncogenic Cbl Mutant 70Z* (1999) (23)
- Protein kinase C‐activating phorbol esters augment expression of T cell receptor genes (1987) (22)
- Requirement of Treg-intrinsic CTLA4/PKCη signaling pathway for suppressing tumor immunity. (2017) (20)
- CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition (2021) (19)
- Regulation of Immune System Cell Functions by Protein Kinase C (2013) (19)
- Mechanism of T-cell lymphomagenesis: transformation of growth-factor-dependent T-lymphoblastoma cells to growth-factor-independent T-lymphoma cells. (1984) (19)
- Role for protein kinase Ctheta (PKCtheta) in TCR/CD28-mediated signaling through the canonical but not the non-canonical pathway for NF-kappaB activation. (2005) (18)
- Mapping of the human protein kinase C-theta (PRKCQ) gene locus to the short arm of chromosome 10 (10p15) by FISH. (1995) (18)
- The nonspecific helper effect of mixed lymphocyte reactions on the induction of T cell‐mediated immunity in vitro (1974) (17)
- Heterogeneity in the development of cytotoxic T lymphocytes in vitro revealed by sensitivity to hydrocortisone (1975) (16)
- Does Def6 deficiency cause autoimmunity? (2009) (16)
- Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP3 receptor 1 promotes Ca2+ signaling in T cells (2014) (16)
- Protein Kinase C θ Deficiency Increases Resistance of C57BL/6J Mice to Plasmodium berghei Infection-Induced Cerebral Malaria (2010) (15)
- Human T cell hybridomas specific for Epstein Barr virus-infected B lymphocytes. (1983) (14)
- SLAT Regulates CD8+ T Cell Clonal Expansion in a Cdc42- and NFAT1-Dependent Manner (2013) (14)
- Construction and characterization of lck- and fyn-specific tRNA: ribozyme chimeras. (1994) (14)
- Helper factor production in murine secondary syngeneic mixed leukocyte reactions. (1982) (13)
- Abnormal antigen receptor-initiated signal transduction in lpr T lymphocytes. (1994) (13)
- NF- k B activation induced by T cell receptor y CD28 costimulation is mediated by protein kinase C- u (2000) (13)
- Phosphotyrosine-dependent interaction between the kinases PKCθ and Zap70 promotes proximal TCR signaling (2019) (13)
- Hodgkin’s lymphoma cells exhibit high expression levels of the PICOT protein (2010) (12)
- Lymphocyte activation and immune regulation (1986) (12)
- A phage display system for detection of T cell receptor-antigen interactions. (1995) (12)
- Regulation of immune responses by E3 ubiquitin-protein ligases. (2002) (12)
- A TRAF-like motif of ICOS controls development of germinal center T follicular helper cells via TBK1 (2016) (12)
- The biologic effects of allogeneic effect factor on T lymphocytes. I. The mitogenic activity and the autonomous induction of cytotoxic T lymphocytes by AEF. (1980) (11)
- Constitutive and mitogen-induced production of T cell growth factor by stable T cell hybridoma lines. (1982) (11)
- The role of p56lck in CD4-mediated suppression of CD3-induced early signaling events in T lymphocytes. (1995) (11)
- SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU) (2012) (11)
- Role of TRAFs in Signaling Pathways Controlling T Follicular Helper Cell Differentiation and T Cell-Dependent Antibody Responses (2018) (11)
- Differentiation of murine bone marrow stem cells in vitro: long-term growth promoted by a lymphocyte-derived mediator. (1981) (10)
- Adaptor Protein SLAT Modulates Fcγ Receptor-mediated Phagocytosis in Murine Macrophages* (2009) (10)
- Widespread Expression of PICOT in Mouse and Human Tissues With Predominant Localization to Epithelium (2010) (10)
- Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells (2017) (10)
- The biologic effects of allogeneic factor on T lymphocytes. II. The specificity of AEF-induced cytotoxic T lymphocytes. (1980) (9)
- T-cell growth factor (interleukin 2). (1981) (9)
- Radiation leukemia virus and X-irradiation induce in C57BL/6 mice two distinct T-cell neoplasms: a growth factor-dependent lymphoma and a growth factor-independent lymphoma. (1987) (9)
- CD45 pre-exclusion from the tips of microvilli establishes a phosphatase-free zone for early TCR triggering (2020) (9)
- SLAT regulates Th 1 and Th 2 inflammatory responses by controlling Ca 2 + / NFAT signaling (2007) (8)
- PICOT binding to the polycomb group protein, EED, alters H3K27 methylation at the MYT1 PRC2 target gene. (2019) (8)
- SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1 (2015) (7)
- Manipulation of cytotoxic T lymphocyte responses to syngeneic tumors. I. Hapten-reactive helper T lymphocytes augment tumor-specific CTL responses in vitro. (1979) (7)
- T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1 (2021) (7)
- Signal transduction pathways in autoimmunity (2001) (7)
- PKCθ: a new target for selective immunosuppression (2012) (7)
- Augmentation of cell mediated lysis (CML) by THF. (1976) (6)
- Biological effects of allogeneic effect factor on T lymphocytes: in vitro induction of cytotoxic T lymphocytes manifesting preferential lytic activity against H-2-identical tumor cells. (1979) (6)
- Analysis of t cell function in autoimmune murine strains. Abstr. (1981) (6)
- To kill, you have to duck an HDAC (2011) (5)
- Protein kinase C-theta (PKCtheta): new perspectives on its functions in T cell biology. (2006) (5)
- Protein Kinase C-Theta (PKCθ): New Perspectives on Its Functions in T Cell Biology (2006) (5)
- Autoreactive rat T-cell lines: establishment and cellular characteristics. (1984) (5)
- Identification of a T cell hybridoma which produces extraordinary quantities of macrophage activating factor. (1982) (5)
- Identification of a Novel Alternatively Spliced Form of Inflammatory Regulator SWAP-70-Like Adapter of T Cells (2017) (4)
- B-cell specific immunoregulatory lymphokines. (1982) (4)
- Publisher Correction: Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis (2019) (4)
- A role for PKCh in outside-in a IIb b 3 signaling (2006) (3)
- pH-sensitive anti-CTLA4 antibodies: yes to efficacy, no to toxicity (2019) (3)
- Distinct Functions of Vav1 in JNK1 Activation in Jurkat T Cells Versus Non‐Haematopoietic Cells (2004) (3)
- Abstract B051: Control of regulatory T (Treg) cell function by protein kinase C-eta (PKCη): A novel target for cancer immunotherapy (2017) (2)
- Differentiation of cytotoxic T lymphocytes enhanced by T cell factors produced during mixed lymphocyte interactions. (1976) (2)
- Recent developments in the study of immunoregulatory lymphokines. (1980) (2)
- Production of antigen-nonspecific immunoregulatory lymphokines by T cell hybridomas. (1982) (2)
- Direct Interaction between Protein Kinase C (cid:117) (PKC (cid:117) ) and 14-3-3 (cid:116) in T Cells: 14-3-3 Overexpression Results in Inhibition of PKC (cid:117) Translocation and Function† (1996) (2)
- TRAF6 regulates TCR signaling via interaction with and modification of LAT adapter (P1178) (2013) (2)
- The biological effects of allogeneic effect factor (AEF) on T lymphocytes. III.--Interferon does not contribute to the biological activities displayed by AEF on both T and B lymphocytes. (1980) (2)
- T-cell hybridomas: sources of specific mediators in the immune system. (1982) (2)
- Interleukin 2 blocks oligodendrocyte progenitor proliferation (1987) (1)
- Leveraging the Treg-intrinsic CTLA4–PKCη signaling pathway for cancer immunotherapy (2021) (1)
- Regulation of T Cell Growth (1985) (1)
- Promotion of hematopoietic stem cell differentiation in vitro by a soluble mediator, allogeneic effect factor. (1980) (1)
- Author response: T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1 (2021) (1)
- Abstract A211: Requirement of Treg-intrinsic CTLA4-PKCeta signaling pathway for suppressing tumor immunity (2019) (1)
- Cytotoxic activity of guinea‐pig lymph‐node cells stimulated in vitro (1978) (1)
- T cell signaling: Protein kinase Cθ, the immunological synapse and characterization of SLAT, a novel T helper 2-specific adapter protein (2002) (1)
- Protein Kinase C-η Deficiency Does Not Impair Antiviral Immunity and CD8+ T Cell Activation (2020) (1)
- Erratum: Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs (2016) (1)
- Immune System Growth Factor Modulation of Neonatal Oligodendrocyte Growth In Vitro (1988) (1)
- Faculty Opinions recommendation of Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. (2019) (1)
- TCR signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1 (2021) (0)
- Immunoregulatory networks. (1980) (0)
- SLAT-IP3R interaction: implications and functional relevance in T cell activation and calcium signaling (P1172) (2013) (0)
- B cell-specific immunoregulatory factors: development of bioassays for growth and differentiation-promoting activities. (1982) (0)
- Activation of p 561 ck by p 72 , k through Physical Association and N-Terminal Tyrosine Phosphorylationt (0)
- Human regulatory T cells suppress CD4+ T cells by rapidly altering the phosphoproteome (2018) (0)
- Stimulation of tumor-specific cytotoxic T-lymphocyte responses in vitro by hapten-reactive helper T lymphocytes and the allogeneic effect. (1980) (0)
- Faculty Opinions recommendation of CD5 signalosome coordinates antagonist TCR signals to control the generation of Treg cells induced by foreign antigens. (2020) (0)
- Control of regulatory T (Treg) cell function by protein kinase C-eta (PKCη): A novel target for cancer immunotherapy (2017) (0)
- Faculty Opinions recommendation of Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity. (2020) (0)
- The relationship between tumor immunogenicity and the appearance of splenic immunosuppressor cells in tumor bearing mice. Abstr. (1977) (0)
- Signaling by Linker for Activation of T Cells Transport but Lipid Raft-Independent Palmitoylation-Dependent Plasma Membrane (2009) (0)
- Faculty Opinions recommendation of Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division. (2018) (0)
- Faculty Opinions recommendation of Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells. (2009) (0)
- Faculty Opinions recommendation of Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity. (2021) (0)
- Protein Kinase C-theta and vimentin modulate multiple facets of Regulatory T-cell function (2016) (0)
- Protein Kinase C-θ and vimentin modulate multiple facets of Regulatory T-cell function. (2016) (0)
- Sumoylation-dependent cSMAC localization of PKC{theta} is critical for T cell activation (2011) (0)
- Interleukin‐2 Blocks Oligodendrocyte Progenitor Proliferation a (1988) (0)
- Faculty Opinions recommendation of Chromatin-associated protein kinase C-θ regulates an inducible gene expression program and microRNAs in human T lymphocytes. (2011) (0)
- Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis (2019) (0)
- During Activation-Induced T Cell Death Calcineurin to Induce Fas Ligand Expression Cooperates with q Protein Kinase C (1999) (0)
- Faculty Opinions recommendation of Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity. (2018) (0)
- Faculty Opinions recommendation of Protein kinase C-theta mediates negative feedback on regulatory T cell function. (2010) (0)
- Protein kinase C-eta is required for Treg-mediated suppression of anti-tumor and viral immunity (2020) (0)
- Pharmacological inhibition of protein kinase C-eta inactivates the contact-dependent suppressive activity of regulatory T cells (Tregs): A novel approach for cancer immunotherapy? (2020) (0)
- Heterogeneity in the generation of cytotoxic t lymphocytes in vitro revealed by sensitivity to hydrocortisone. Abstr. (1976) (0)
- Title : Protein Kinase C-theta interacts with mTORC 2 and vimentin to limit Regulatory T-cell function (2016) (0)
- Faculty Opinions recommendation of Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cells. (2008) (0)
- Navigating the leukocyte signaling maze guided by Ariadne's thread (2009) (0)
- Erratum: A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1 (2016) (0)
- Faculty Opinions recommendation of A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity. (2011) (0)
- Palmitoylation‐dependent plasma membrane transport, but lipid raft‐independent signaling function, of linker for activation of T cells (LAT) (2008) (0)
- Faculty Opinions recommendation of Tumor suppressor TSC1 is critical for T-cell anergy. (2012) (0)
- The Peptidyl-Prolyl cis-trans isomerase, Pin1, associates with Protein Kinase C θ via a critical Phospho-Thr-Pro motif in the V3 regulatory domain (2023) (0)
- Sumoylation-dependent cSMAC localization of PKCθ is critical for T cell activation (109.25) (2011) (0)
- Existence of T lymphocytes manifesting self-reactivity indistinguishable from alloreactivity: implications for self-recognition and MHC polymorphism. (1981) (0)
- Faculty Opinions recommendation of The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. (2008) (0)
- Faculty Opinions recommendation of PKC-theta selectively controls the adhesion-stimulating molecule Rap1. (2009) (0)
- Extra-Nuclear and Nuclear Rarα Reciprocally Control Tcr-Induced Proliferation and Differentiation (2019) (0)
- Faculty Opinions recommendation of Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells. (2021) (0)
- Faculty Opinions recommendation of STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death. (2019) (0)
- Faculty Opinions recommendation of The kinase PKCα selectively upregulates interleukin-17A during Th17 cell immune responses. (2013) (0)
- Construction of T-cell hybridomas secreting distinct antigen-nonspecific lymphokines☆☆☆ (1982) (0)
- The role of protein kinase C! inT cell biology (2012) (0)
- Functional T Cell Hybridomas Producing Nonspecific Immunoregulatory Factors (2019) (0)
- Protein kinase C-eta (PKCη) is dispensable for the activation and function of CD8+T cells (2019) (0)
- Proceedings: The helper effect of mixed lymphocyte culture supernatants on an in vitro T cell-mediated mouse transplantation reaction. (1975) (0)
- Protein kinase C-y (PKCy): it’s all about location, location, location (2003) (0)
- Faculty Opinions recommendation of LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function. (2021) (0)
- Faculty Opinions recommendation of Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance. (2009) (0)
- Science Signaling Podcast: 30 September 2014 (2014) (0)
- Antigen‐induced translocation of SLAT to immunological synapse is required for NFAT activation and Th1/Th2 immune responses (2008) (0)
- Costimulation (PP-102) (2010) (0)
- The adaptor protein 3 BP 2 associates VAV guanine nucleotide exchange factors to regulate NFAT activation by the B cell antigen receptor Running Title : Role of 3 BP 2 in BCR signaling (2004) (0)
- Faculty Opinions recommendation of Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. (2009) (0)
- Proteinsof Src Homology 2 Domain-Containing Phosphorylation of Cbl and Its Recruitment Protein Kinase C Activation Inhibits Tyrosine (1999) (0)
- Faculty of 1000 evaluation for A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy. (2018) (0)
- BADSurvival Signal Via Phosphorylation of Mediates a Selective T θ Protein Kinase C (2013) (0)
- Modification of LAT Adapter Signaling via Interaction with and TNFR-Associated Factor 6 Regulates TCR (2013) (0)
- C Inflammatory Responses by Protein Kinase Differential Regulation of Th2 and Th1 Lung (2004) (0)
- Costimulation (WS-102) Chairpersons: Miyuki Azuma, Tania Watts (2010) (0)
- NFAT 1-Dependent Manner Expansion in a Cdc 42-and T Cell Clonal + SLAT Regulates CD 8 (2012) (0)
- Functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation (2000) (0)
- Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function (2015) (0)
- Faculty Opinions recommendation of An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes. (2010) (0)
- PROTEIN KINASE Cµ IN TC ELL ACTIVATION (2002) (0)
- Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine. (2023) (0)
- Faculty Opinions recommendation of Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance. (2016) (0)
- SLAT/Def6 Knock-Out (KO) Mice Exhibit Profoundly Reduced Capacity to Develop Experimental Autoimmune Uveitis (EAU) (2011) (0)
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What Schools Are Affiliated With Amnon Altman?
Amnon Altman is affiliated with the following schools:
