Amos Smith
#24,391
Most Influential Person Now
American chemist
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Chemistry
Amos Smith's Degrees
- PhD Chemistry University of California, Berkeley
- Masters Chemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Amos Smith Influential?
(Suggest an Edit or Addition)According to Wikipedia, Amos B. Smith III is an American chemist. Biography He is most notable for his research in the total synthesis of complex natural product, as well as the chemistry of mammalian pheromones and chemical communication.
Amos Smith's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil (2005) (769)
- Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions (2014) (413)
- The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice (2012) (329)
- Carboxylic Acid (Bio)Isosteres in Drug Design (2013) (308)
- Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy (2010) (264)
- Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins. (2004) (249)
- Structure and bonding in alkali-metal-doped C60 (1991) (248)
- Evolution of dithiane-based strategies for the construction of architecturally complex natural products. (2004) (228)
- Compressibility of Solid C60 (1991) (210)
- Nonpeptidal peptidomimetics with a β-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist (1992) (192)
- Orientational Disorder in Solvent-Free Solid C70 (1991) (184)
- Evolution of a Gram-Scale Synthesis of (+)-Discodermolide (2000) (184)
- Soluble CD4 and CD4-Mimetic Compounds Inhibit HIV-1 Infection by Induction of a Short-Lived Activated State (2009) (171)
- Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120. (2008) (158)
- Microtubule stabilizing agents as potential treatment for Alzheimer's disease and related neurodegenerative tauopathies. (2012) (153)
- 1,2-Methanobuckminsterfullerene (C61H2), the parent fullerene cyclopropane: synthesis and structure (1993) (146)
- Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120. (2006) (145)
- Compressibility of M3C60 Fullerene Superconductors: Relation Between Tc and Lattice Parameter (1992) (145)
- Transient absorption studies of C60 in solution (1991) (142)
- The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies. (2011) (141)
- Synthesis of Prototypical Fullerene Cyclopropanes and Annulenes. Isomer Differentiation via NMR and UV Spectroscopy (1995) (140)
- Structure Property Relationships of Carboxylic Acid Isosteres (2016) (138)
- Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. (2009) (131)
- Enantioselective Synthesis of Diverse .alpha.-Amino Phosphonate Diesters (1995) (130)
- Electrochemical intercalation of lithium into solid fullerene C60 (1992) (122)
- Total syntheses of (+)-zampanolide and (+)-dactylolide exploiting a unified strategy. (2002) (122)
- Unusual Pungency from Extra-Virgin Olive Oil Is Attributable to Restricted Spatial Expression of the Receptor of Oleocanthal (2011) (121)
- Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET. (2019) (120)
- Localized Changes in the gp120 Envelope Glycoprotein Confer Resistance to Human Immunodeficiency Virus Entry Inhibitors BMS-806 and #155 (2004) (119)
- Peptide/Protein Stapling and Unstapling: Introduction of s-Tetrazine, Photochemical Release, and Regeneration of the Peptide/Protein (2015) (117)
- Contribution of Intrinsic Reactivity of the HIV-1 Envelope Glycoproteins to CD4-Independent Infection and Global Inhibitor Sensitivity (2011) (117)
- Aminothienopyridazines and Methylene Blue Affect Tau Fibrillization via Cysteine Oxidation* (2013) (115)
- A Small-Molecule Oxocarbazate Inhibitor of Human Cathepsin L Blocks Severe Acute Respiratory Syndrome and Ebola Pseudotype Virus Infection into Human Embryonic Kidney 293T cells (2010) (111)
- Total Synthesis of (+)-Lactacystin (1996) (111)
- Synthesis and reactions of simple 3(2H)-furanones (1981) (111)
- Azide and Cyanide Displacements via Hypervalent Silicate Intermediates. (1999) (107)
- CD4 mimetics sensitize HIV-1-infected cells to ADCC (2015) (107)
- Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins (2016) (105)
- Picosecond photoisomerization and rotational reorientation dynamics in solution (1986) (102)
- Solid-state Chemistry of Fullerene-Based Materials (1992) (100)
- Evolution of multi-component anion relay chemistry (ARC): construction of architecturally complex natural and unnatural products. (2008) (97)
- Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening. (2009) (96)
- Design, synthesis, and crystal structure of a pyrrolinone-based peptidomimetic possessing the conformation of a .beta.-strand: potential application to the design of novel inhibitors of proteolytic enzymes (1992) (96)
- Evolution of the Petasis-Ferrier union/rearrangement tactic: construction of architecturally complex natural products possessing the ubiquitous cis-2,6-substituted tetrahydropyran structural element. (2008) (95)
- Effect of oleocanthal and its derivatives on inflammatory response induced by lipopolysaccharide in a murine chondrocyte cell line. (2010) (94)
- Total synthesis of (-)-calyciphylline N. (2014) (93)
- Iodine monobromide (IBr) at low temperature: enhanced diastereoselectivity in electrophilic cyclizations of homoallylic carbonates (1993) (92)
- A general, convergent strategy for the construction of indolizidine alkaloids: total syntheses of (-)-indolizidine 223AB and alkaloid (-)-205B. (2006) (92)
- Tau-directed drug discovery for Alzheimer's disease and related tauopathies: A focus on tau assembly inhibitors (2010) (92)
- Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease. (2014) (91)
- Synthesis of oxo- and methylene-bridged C60 dimers, the first well-characterized species containing fullerene-fullerene bonds. (1995) (90)
- Access to the akuammiline family of alkaloids: total synthesis of (+)-scholarisine A. (2013) (87)
- Phyllanthoside-phyllanthostatin synthetic studies. 8. Total synthesis of (+)-phyllanthoside. Development of the Mitsunobu glycosyl ester protocol (1991) (83)
- Further evidence for the anti-inflammatory activity of oleocanthal: inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes. (2012) (82)
- Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors. (2012) (81)
- Total synthesis of -macrolactin A (1996) (81)
- Asymmetric Synthesis of .alpha.-Aminophosphonates via Diastereoselective Addition of Lithium Diethyl Phosphite to Chelating Imines (1994) (81)
- X-Ray Diffaction Evidence for Nonstoichiometric Rubidium-C60 Intercalation Compounds (1991) (81)
- The Daphniphyllum Alkaloids: Total Synthesis of (−)-Calyciphylline N (2015) (80)
- Brain-Penetrant, Orally Bioavailable Microtubule-Stabilizing Small Molecules Are Potential Candidate Therapeutics for Alzheimer’s Disease and Related Tauopathies (2014) (80)
- Total synthesis of milbemycin .beta.3 (1982) (80)
- Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist (2014) (79)
- Total synthesis of (+)-scholarisine A. (2012) (79)
- Multicomponent linchpin couplings. Reaction of dithiane anions with terminal epoxides, epichlorohydrin, and vinyl epoxides: efficient, rapid, and stereocontrolled assembly of advanced fragments for complex molecule synthesis. (2003) (79)
- Anion relay chemistry: an effective tactic for diversity oriented synthesis. (2006) (79)
- Synthesis and assignment of absolute configuration of (-)-oleocanthal: a potent, naturally occurring non-steroidal anti-inflammatory and anti-oxidant agent derived from extra virgin olive oils. (2005) (79)
- Milbemycin-avermectin studies. 5. Total synthesis of milbemycin .beta.3 and its C(12) epimer (1986) (78)
- Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish (2010) (77)
- Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge". (2011) (77)
- An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity. (2019) (77)
- De Novo Design, Synthesis, and X-ray Crystal Structures of Pyrrolinone-Based .beta.-Strand Peptidomimetics (1994) (76)
- Total Syntheses of (−)-Macrolactin A, (+)-Macrolactin E, and (−)-Macrolactinic Acid: An Exercise in Stille Cross-Coupling Chemistry (1998) (75)
- Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs (2017) (75)
- Evolution of a total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis strategy. (2006) (73)
- Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition. (2016) (73)
- Synthesis and configurational assignment of geiparvarin: a novel antitumor agent (1981) (72)
- Potentiation of Taxol Efficacy by Discodermolide in Ovarian Carcinoma Xenograft-Bearing Mice (2006) (72)
- Activation of the Steroid and Xenobiotic Receptor (Human Pregnane X Receptor) by Nontaxane Microtubule-Stabilizing Agents (2005) (70)
- Photophysical properties of solid films of fullerene, C60 (1991) (68)
- Relative and Absolute Stereochemistry of Pyripyropene A, A Potent, Bioavailable Inhibitor of Acyl-CoA:Cholesterol Acyltransferase (ACAT) (1994) (68)
- A monolayer of C60 tethered to the surface of an inorganic substrate : assembly and structure (1993) (68)
- Total synthesis of (.+-.)-modhephene (1981) (66)
- Peptide bond formation via catalytic antibodies: Synthesis of a novel phosphonate diester hapten (1994) (66)
- Microtubule-stabilising drugs for therapy of Alzheimer’s disease and other neurodegenerative disorders with axonal transport impairments (2005) (66)
- Fluorinated fullerenes: synthesis, structure, and properties (1993) (65)
- Two-dimensional infrared measurements of the coupling between amide modes of an α-helix (2003) (65)
- Total synthesis of (+)-lactacystin, the first non-protein neurotrophic factor (1993) (65)
- Structural phase transitions and orientational ordering in C70 (1993) (65)
- Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening. (2011) (65)
- Total synthesis of (+)-13-deoxytedanolide. (2003) (65)
- Spongistatin synthetic studies. An efficient, second-generation construction of an advanced ABCD intermediate. (2002) (64)
- Assembly of (−)-Cylindrocyclophanes A and F via Remarkable Olefin Metathesis Dimerizations (2000) (64)
- Additions and Corrections - A Strategy for the Total Synthesis of Jatrophone: Synthesis of Normethyljatrophone (1981) (64)
- Total synthesis of the neotropical poison-frog alkaloid (-)-205B. (2005) (63)
- Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid (2012) (62)
- Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity (2015) (62)
- Langmuir films of fullerene C60, fullerene epoxide C60O, and dihydrofulleroid C61H2 (1993) (61)
- Total synthesis of (-)-paspaline (1985) (61)
- The first design and synthesis of a steroidal peptidomimetic. The potential value of peptidomimetics in elucidating the bioactive conformation of peptide ligands (1992) (61)
- Total synthesis of (+)-sorangicin A. (2009) (60)
- Transitions to and from the CD4-Bound Conformation Are Modulated by a Single-Residue Change in the Human Immunodeficiency Virus Type 1 gp120 Inner Domain (2009) (59)
- Ruthenium Tetroxide Oxidation of Simple Ethers: A Systematic Study (1980) (59)
- The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions (2017) (59)
- Total Synthesis of (+)-Calyculin A and (−)-Calyculin B: Cyanotetraene Construction, Asymmetric Synthesis of the C(26−37) Oxazole, Fragment Assembly, and Final Elaboration (1999) (59)
- Syntheses of (-)-oleocanthal, a natural NSAID found in extra virgin olive oil, the (-)-deacetoxy-oleuropein aglycone, and related analogues. (2007) (59)
- Total Synthesis of Immunosuppressants: Unified Strategies Exploiting Dithiane Couplings and σ-Bond Olefin Constructions† (1998) (59)
- Phosphonate Diester and Phosphonamide Synthesis. Reaction Coordinate Analysis by 31P NMR Spectroscopy: Identification of Pyrophosphonate Anhydrides and Highly Reactive Phosphonylammonium Salts1 (1997) (59)
- FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)–C(34) fragment of FK-506, FR-900520, and FR-900523 (1989) (59)
- Multicomponent linchpin coupling of silyl dithianes employing an N-Ts aziridine as the second electrophile: synthesis of (-)-indolizidine 223AB. (2004) (58)
- Total Synthesis of Rapamycin and Demethoxyrapamycin (1995) (57)
- Indole diterpene synthetic studies. 8. The total synthesis of (+)-paspalicine and (+)-paspalinine (1992) (57)
- AN NMR STUDY OF HE2 INSIDE C70 (1998) (57)
- Tetrazine phototriggers: probes for peptide dynamics. (2010) (56)
- Evolution of the total synthesis of (-)-okilactomycin exploiting a tandem oxy-cope rearrangement/oxidation, a Petasis-Ferrier union/rearrangement, and ring-closing metathesis. (2009) (56)
- Total syntheses of (+)-lyconadin A and (-)-lyconadin B. (2007) (56)
- Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins (2016) (55)
- Total synthesis of (+)-spongistatin 1. An effective second-generation construction of an advanced EF Wittig salt, fragment union, and final elaboration. (2003) (55)
- Total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis synthetic strategy. (2005) (55)
- Tremorgenic indole alkaloids. The total synthesis of (-)-penitrem D. (2003) (54)
- Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus. (2007) (54)
- Photochemical reactions of 1-cyclopentenyl and 1-cyclohexenyl ketones (1973) (54)
- Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization. (2013) (54)
- TOTAL SYNTHESIS OF (+)-CALYCULIN A AND (-)-CALYCULIN B : ASYMMETRIC SYNTHESIS OF THE C(9-25) SPIROKETAL DIPROPIONATE SUBUNIT (1999) (54)
- Spongipyran Synthetic Studies. Evolution of a Scalable Total Synthesis of (+)-Spongistatin 1. (2009) (54)
- Isomerization processes of electronically excited stilbene and diphenylbutadiene in liquids. Are they one-dimensional? (1989) (53)
- A Unified Total Synthesis of the Immunomodulators (−)-Rapamycin and (−)-27-Demethoxyrapamycin: Assembly of the Common C(1−20) Perimeter and Final Elaboration (1997) (53)
- Organometallic reagents in synthesis : A new protocol for construction of the indole nucleus (1986) (53)
- Total Synthesis of (+)-Pyripyropene A. A Potent, Orally Bioavailable Inhibitor of Acyl-CoA:Cholesterol Acyltransferase (1995) (53)
- One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor. (2014) (52)
- An enantioselective synthesis of the C(10) to C(23) backbone of the potent immunosuppressant FK506 (1989) (52)
- Spongistatin synthetic studies. 1. Construction of a C(29–48) subtarget (1997) (52)
- (+)-Discodermolide: Total Synthesis, Construction of Novel Analogues, and Biological Evaluation. (2008) (52)
- Unification of anion relay chemistry with the Takeda and Hiyama cross-coupling reactions: identification of an effective silicon-based transfer agent. (2012) (52)
- Toward understanding how the lactone moiety of discodermolide affects activity. (2005) (52)
- Indole diterpene synthetic studies. 2. First-generation total synthesis of (-)-paspaline (1989) (51)
- Interactions of Halichondrin B and Eribulin with Tubulin (2011) (51)
- The beta-D-glucose scaffold as a beta-turn mimetic. (2009) (51)
- Human Cytosolic Extracts Stabilize the HIV-1 Core (2013) (51)
- Total synthesis of (+)-psymberin (irciniastatin A): catalytic reagent control as the strategic cornerstone. (2008) (51)
- Identification of a Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Variant Resistant to Cold Inactivation (2009) (51)
- An efficient approach to chiral, nonracemic trans-decahydro-5,8a-dimethyl-1,6-naphthalenedione derivatives. Total synthesis of (+)-pallescensin A (1984) (50)
- Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes. (2016) (50)
- Plant anticancer agents. 28. New antileukemic jatrophone derivatives from Jatropha gossypiifolia: structural and stereochemical assignment through nuclear magnetic resonance spectroscopy (1983) (50)
- Total Synthesis of (−)-Mandelalide A Exploiting Anion Relay Chemistry (ARC): Identification of a Type II ARC/CuCN Cross-Coupling Protocol (2016) (50)
- Total synthesis of the marine natural product (-)-clavosolide A. A showcase for the Petasis-Ferrier union/rearrangement tactic. (2006) (50)
- Total Syntheses of (+)-Acutiphycin and (+)-trans-20,21-Didehydroacutiphycin (1995) (49)
- Total synthesis of (+)-tedanolide. (2007) (48)
- The orientational phase transition in solid buckminsterfullerene epoxide (C60O) (1992) (48)
- Copper-catalyzed electrophilic amination of organolithiums mediated by recoverable siloxane transfer agents. (2013) (48)
- Oxidation of β-Hydroxyketones and Esters: A Convenient Synthesis of 1,3-Diketones and β-Ketoesters (1981) (48)
- Stereocontrolled total synthesis of (.+-.)-pentenomycins. I-III, their epimers, and dehydropentenomycin I (1982) (48)
- Total synthesis of (+)-jatropholones A and B: exploitation of the high-pressure technique (1986) (48)
- The acid promoted decomposition of α-diazo ketones (1981) (48)
- Photochemistry of cyclopentenones. Hydrogen abstraction by the .beta.-carbon atom (1972) (47)
- Discovery of brain-penetrant, orally bioavailable aminothienopyridazine inhibitors of tau aggregation. (2010) (47)
- Characterization of a sex pheromone in the blue crab,Callinectes sapidus: Crustecdysone studies (1984) (47)
- CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies (2014) (47)
- Direct modulation of microtubule stability contributes to anthracene general anesthesia. (2013) (47)
- Pyrrolinone-Based HIV Protease Inhibitors. Design, Synthesis, and Antiviral Activity: Evidence for Improved Transport (1995) (47)
- Diversity-oriented synthesis leads to an effective class of bifunctional linchpins uniting anion relay chemistry (ARC) with benzyne reactivity (2011) (46)
- A Unified Total Synthesis of the Immunomodulators (−)-Rapamycin and (−)-27-Demethoxyrapamycin: Construction of the C(21−42) Perimeters (1997) (46)
- Rotational dynamics and orientational melting of C60 : a neutron scattering study (1992) (46)
- The [1,5]-Brook rearrangement: an initial application in anion relay chemistry. (2006) (46)
- A unified approach to the tedanolides: total synthesis of (+)-13-deoxytedanolide. (2004) (46)
- Gram-scale synthesis of (+)-spongistatin 1: development of an improved, scalable synthesis of the F-ring subunit, fragment union, and final elaboration. (2008) (46)
- Use of self-assembled monolayers to covalently tether protein monolayers to the surface of solid substrates (1993) (45)
- Total Synthesis of (−)-Penitrem D (2000) (45)
- Frustration and helicity in the ordered phases of a discotic compound (1989) (45)
- Solid phase synthesis of 2-aminobenzothiazoles. (2010) (45)
- Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site (2014) (45)
- Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells (2015) (44)
- Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy (2016) (44)
- Total synthesis of (+)-quadrone: assignment of absolute stereochemistry (1984) (44)
- Total Syntheses of (+)-Trienomycins A and F via a Unified Strategy (1996) (44)
- Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer’s Disease and Related Tauopathies (2016) (44)
- Synthesis and Characterization of the First C70O Epoxides. Utilization of 3He NMR in Analysis of Fullerene Derivatives (1996) (43)
- Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathies. (2012) (43)
- Nonequilibrium dynamics of helix reorganization observed by transient 2D IR spectroscopy (2013) (43)
- Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization. (2009) (43)
- Oxidative [1,2]-Brook Rearrangements Exploiting Single-Electron Transfer: Photoredox-Catalyzed Alkylations and Arylations. (2017) (43)
- A stereospecific total synthesis of (.+-.)-pentenomycin I, (.+-.)-pentenomycin II, and dehydropentenomycin I exploiting a versatile latent .alpha.-oxovinyl anion equivalent (1978) (43)
- Total synthesis of (+)-phyllanthocin (1987) (43)
- A unified synthetic strategy to the Cryptocarya family of natural products exploiting Anion Relay Chemistry (ARC). (2013) (42)
- SPONGISTATIN SYNTHETIC STUDIES. 2. ASSEMBLY OF THE C(18-28) SPIROKETAL (1997) (42)
- Phyllanthoside-phyllanthostatin synthetic studies. 7. Total synthesis of (+)-phyllanthocin and (+)-phyllanthocindiol (1991) (42)
- Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors. (2003) (42)
- CONVENIENT WACKER OXIDATIONS WITH SUBSTOICHIOMETRIC CUPRIC ACETATE (1998) (42)
- Peptide-small molecule hybrids via orthogonal deprotection-chemoselective conjugation to cysteine-anchored scaffolds. A model study. (2002) (42)
- An efficient synthesis of glycosyl esters exploiting the mitsunobu reaction. (1987) (41)
- C≡N stretching vibration of 5-cyanotryptophan as an infrared probe of protein local environment: what determines its frequency? (2016) (41)
- Total synthesis of (-)-okilactomycin. (2007) (41)
- Spongistatin synthetic studies. 3. Construction of the C(1–17) spiroketal (1997) (41)
- The spirastrellolides: construction of the southern C(1)-C(25) fragment exploiting anion relay chemistry. (2007) (41)
- A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin. (2006) (41)
- Total syntheses of (+)-paspalicine and (+)-paspalinine (1990) (41)
- (+)-Sorangicin A synthetic studies. Construction of the C(1-15) and C(16-29) subtargets. (2005) (40)
- Enhancement of Through-Space and Through-Bond .pi.-Orbital Interactions. Syntheses and Properties of Permethylated and Perspirocyclopropanated Cyclotetradeca-1,3,6,9,12-pentayne (1994) (40)
- Two Families of Env Antibodies Efficiently Engage Fc-Gamma Receptors and Eliminate HIV-1-Infected Cells (2018) (40)
- Spectroscopy, photophysics, and photochemistry of dimethyl-s-tetrazine and phenyl-s-tetrazine in crystals and mixed crystals at low temperatures (1977) (40)
- Total synthesis of the paniculides (1983) (40)
- Photochemical reactions of simple cyclopentenones (1971) (40)
- Total synthesis of (+)-discodermolide: a highly convergent fourth-generation approach. (2005) (40)
- Synthesis of novel HIV-1 protease inhibitors based on carbohydrate scaffolds (2003) (40)
- Preparation, reactivity, and spectral properties of 1,3-dioxin vinylogous esters: versatile .beta.-ketovinyl cation equivalents (1988) (40)
- Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors (2016) (40)
- An efficient new method for the desulfonylation of β-keto phenylsulfones (1989) (39)
- Novel ligands lacking a positive charge for the δ- and μ-opioid receptors (2000) (39)
- Calyculin synthetic studies. 2. Stereocontrolled assembly of the C(9)-C(13) dithiane and C(26)-C(37) oxazole intermediates (1991) (39)
- Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents. (2003) (39)
- Indole diterpene synthetic studies. 5. Development of a unified synthetic strategy; a stereocontrolled, second-generation synthesis of (-)-paspaline (1989) (39)
- Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D (2016) (39)
- Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1. (2008) (39)
- A second-generation total synthesis of (+)-phorboxazole A. (2008) (38)
- Total Synthesis of (−)-Cylindrocyclophane F (1999) (38)
- A practical improvement, enhancing the large-scale synthesis of (+)-discodermolide: a third-generation approach. (2003) (38)
- Total synthesis of the latrunculins (1992) (37)
- Applications of an asymmetric [2 + 2]-photocycloaddition. Total synthesis of (-)-echinosporin. Construction of an advanced 11-deoxyprostaglandin intermediate (1992) (37)
- Total synthesis of the cytotoxic macrocycle (+)-hitachimycin (1992) (37)
- BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity (2017) (36)
- MT-Stabilizer, Dictyostatin, Exhibits Prolonged Brain Retention and Activity: Potential Therapeutic Implications. (2013) (35)
- Total synthesis of (−)-salicylihalamide A and related congeners (2002) (35)
- Spirastrellolide Studies. Synthesis of the C(1)-C(25) Southern Hemispheres of Spirastrellolides A and B, Exploiting Anion Relay Chemistry. (2010) (35)
- Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity (2016) (35)
- Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide. (2005) (35)
- Total Synthesis of (-)-Nodulisporic Acid D. (2015) (35)
- Design and Synthesis of a Competent Pyrrolinone−Peptide Hybrid Ligand for the Class II Major Histocompatibility Complex Protein HLA-DR1 (1999) (35)
- Some Binding‐Related Drug Properties are Dependent on Thermodynamic Signature (2011) (34)
- Nitrene additions to [60]fullerene do not generate [6,5] aziridines (1996) (34)
- Total synthesis of (.+-.)-modhephene and its epimer, (.+-.)-epimodhephene (1982) (34)
- Lewis acid promoted decomposition of unsaturated .alpha.-diazo ketones. 1. An efficient approach to simple and annulated cyclopentenones (1981) (34)
- Through-bond/through-space anion relay chemistry exploiting vinylepoxides as bifunctional linchpins. (2014) (34)
- The lyconadins: enantioselective total syntheses of (+)-lyconadin A and (-)-lyconadin B. (2008) (34)
- Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds (2016) (34)
- SYNTHESIS AND 3HE NMR STUDIES OF C60 AND C70 EPOXIDE, CYCLOPROPANE, AND ANNULENE DERIVATIVES CONTAINING ENDOHEDRAL HELIUM (1994) (34)
- Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L (2008) (34)
- Structure and mesophases of hexacyclen derivatives (1991) (33)
- Total syntheses of the assigned structures of lituarines B and C. (2008) (33)
- Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer’s and Other Neurodegenerative Diseases (2017) (33)
- Uniting anion relay chemistry with Pd-mediated cross coupling: design, synthesis and evaluation of bifunctional aryl and vinyl silane linchpins. (2010) (33)
- Stereoelectronic effects in the cationic rearrangements of [4.3.2]propellanes (1985) (33)
- Aminothienopyridazine inhibitors of tau aggregation: evaluation of structure-activity relationship leads to selection of candidates with desirable in vivo properties. (2012) (33)
- Diversity-oriented synthesis of 2,4,6-trisubstituted piperidines via type II anion relay chemistry. (2011) (33)
- An asymmetric synthesis of (+)-kjellmanianone (1982) (32)
- (+)-Phorboxazole A synthetic studies. A highly convergent, second generation total synthesis of (+)-phorboxazole A. (2005) (32)
- Preparation and reactions of 2,2-dimethyl-4-cyclopentene-1,3-dione (1970) (32)
- Discodermolide analogues as the chemical component of combination bacteriolytic therapy. (2005) (32)
- Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes (2015) (32)
- The versatile steroid nucleus: Design and synthesis of a peptidomimetic employing this novel scaffold. (1993) (32)
- Enantioselective synthesis of (+)-kjellmanianone (1991) (32)
- Total synthesis of (+)-hydroxyjatrophone A and (+)-hydroxyjatrophone B (1989) (32)
- Total Synthesis of (-)-Furaquinocin C (1995) (31)
- Construction of a C(30-38) dioxabicyclo[3.2.1]octane subtarget for (+)-sorangicin A, exploiting a regio- and stereocontrolled acid-catalyzed epoxide ring opening. (2004) (31)
- Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. (2002) (31)
- Total synthesis of natural (-)-echinosporin. Determination of the absolute configuration (1989) (30)
- Cuprate additions to 5-methoxycyclopentenones: a novel stereoelectronic effect (1988) (30)
- Vinylogous Wolff rearrangement. 4. General reaction of .beta.,.gamma.-unsaturated .alpha.'-diazo ketones (1984) (30)
- Revised structures of antheliolides A and B (1989) (30)
- Spongistatin synthetic studies. evolution of a scalable synthesis for the EF fragment of (+)-Spongistatin 1 exploiting a Petasis-Ferrier union/rearrangement tactic. (2004) (30)
- Total synthesis of (-)-2-epi-peloruside A. (2008) (30)
- Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds (2016) (30)
- Cyclopentane-1,3-dione: a novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists. (2011) (30)
- Tremorgenic indole alkaloids. 9. asymmetric construction of an advanced F-G-H-ring lactone precursor for the synthesis of Penitrem D (1995) (29)
- Total synthesis of (-)-21-isopentenylpaxilline. (2003) (29)
- X-ray Powder Diffraction Structure of Triclinic C60Br24(Br2)2 (1995) (29)
- HORMONAL MODULATION OF PHEROMONE-MEDIATED BEHAVIOR IN A CRUSTACEAN (1987) (29)
- Feeding Responses to Predator-Based Repellents in the Mountain Beaver ( Aplodontia rufa ) (1995) (29)
- An efficient general synthesis of ω-olefinic methyl esters (1978) (29)
- Total synthesis of (.+-.)-breynolide, an aglycon derivative of the orally active hypocholesterolemic agent breynin A (1992) (29)
- An expedient synthesis of substituted indoles (1985) (28)
- Fourier Transform Infrared Absorption Study of Hexa(hexylthio)triphenylene: A Discotic Liquid Crystal (1991) (28)
- Formal total synthesis of FK506. Concise construction of the C(10)-C(34) segment via an effective coupling tactic (1994) (28)
- Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists. (2017) (28)
- Indole diterpene synthetic studies: development of a second-generation synthetic strategy for (+)-nodulisporic acids A and B. (2007) (28)
- Synthesis of (-)-bertyadionol (1986) (28)
- Proteins: biologically relevant components of the scent marks of a primate (Saguinus fuscicollis) (1990) (28)
- Benzyl and phenylthiomethyl silanes: a new class of bifunctional linchpins for type II anion relay chemistry (ARC). (2010) (28)
- An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors (2011) (28)
- Total Synthesis of (+)-Calyculin A and (−)-Calyculin B (1998) (28)
- TOTAL SYNTHESIS OF HIBISCONE C (GMELOFURAN) (1982) (28)
- Ortho-TMS benzaldehyde: an effective linchpin for type II anion relay chemistry (ARC). (2008) (28)
- Anion relay chemistry: access to the type II ARC reaction manifold through a fundamentally different reaction pathway exploiting 1-oxa-2-silacyclopentanes and related congeners. (2011) (28)
- Design, Synthesis, and Validation of an Effective, Reusable Silicon-Based Transfer Agent for Room-Temperature Pd-Catalyzed Cross-Coupling Reactions of Aryl and Heteroaryl Chlorides with Readily Available Aryl Lithium Reagents. (2016) (28)
- Biomimetic total synthesis of the ACAT inhibitor (+)-pyripyropene E (1996) (27)
- Reentrant isotropic phase in a discotic liquid crystal mixture (1989) (27)
- Generation of Dithianyl and Dioxolanyl Radicals Using Photoredox Catalysis: Application in the Total Synthesis of the Danshenspiroketallactones via Radical Relay Chemistry. (2019) (27)
- Indole diterpene synthetic studies. Total synthesis of (+)-nodulisporic acid F and construction of the heptacyclic cores of (+)-nodulisporic acids A and B and (-)-nodulisporic acid D. (2007) (27)
- Chemical Communication in the Guinea Pig: Urinary Components of Low Volatility and Their Access to the Vomeronasal Organ (1980) (27)
- EFFICIENT REGIOCONTROLLED SYNTHESIS OF SARKOMYCIN AND HOMOSARKOMYCIN (1982) (27)
- Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120 (2010) (27)
- Spongipyran Synthetic Studies. Total Synthesis of (+)-Spongistatin 2. (2009) (27)
- Aziridines. XVIII. Reactions of a 1,3-diazabicyclo-[3.1.0]hex-3-ene with alkenes, alkynes, and diethyl azodicarboxylate (1968) (27)
- A new modular indole synthesis. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B. (2006) (27)
- Nucleophilic ring cleavage of mono-activated cyclopropanes via sodium and lithium phenyl selenolate (1978) (27)
- Development of a Scalable Synthesis of a Common Eastern Tricyclic Lactone for Construction of the Nodulisporic Acids (2007) (27)
- Chemical Signals in Callitrichid Monkeys — A Comparative Review (1986) (26)
- Tremorgenic indole alkaloid studies. 6. Preparation of an advanced intermediate for the synthesis of penitrem D. Synthesis of an indole oxocane (1989) (26)
- New Analogs of the Pyripyropene Family of ACAT Inhibitors via α-Pyrone Fragmentation and γ-Acylation/Cyclization (1997) (26)
- Andrographolide: an X-ray crystallographic analysis (1982) (26)
- Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide. (2005) (26)
- Stereocontrolled total synthesis of (.+-.)-xanthocidin, two diastereomers, (.+-.)-epixanthocidin and (.+-.)-.beta.-isoxanthocidin, and (.+-.)-dedihydroxy-4,5-didehydroxanthocidin, a likely biosynthetic precursor (1983) (26)
- New drugs from ancient natural foods. Oleocanthal, the natural occurring spicy compound of olive oil: a brief history. (2015) (26)
- Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity. (2011) (26)
- Pharmacokinetic, pharmacodynamic and metabolic characterization of a brain retentive microtubule (MT)-stabilizing triazolopyrimidine. (2015) (26)
- Structural Basis of Microtubule Stabilization by Discodermolide (2017) (25)
- Multicomponent type II anion relay chemistry (ARC): one-pot syntheses of 2,3-disubstituted furans and thiophenes. (2009) (25)
- Construction of 5,6-Ring Fused 2-Pyridones: An Effective Annulation Tactic Achieved in Water. (2009) (25)
- Production and Oxidation of Indole by Haemophilus influenzae(*) (1995) (25)
- Intramolecular [2+2] photocyclizations. II: Total synthesis of (±)-hibiscone C (gmelofuran) (1984) (25)
- Total synthesis of (+)-irciniastatin A (a.k.a. psymberin) and (-)-irciniastatin B. (2013) (25)
- Molecular orientational dynamics in solid C70: Investigation by one‐ and two‐dimensional magic angle spinning nuclear magnetic resonance (1993) (25)
- Polymer-supported siloxane transfer agents for Pd-catalyzed cross-coupling reactions. (2013) (24)
- Exploitation of the vinylogous Wolff rearrangement. An efficient total synthesis of (.+-.)-mayurone, (.+-.)-thujopsene, and (.+-.)-thujopsadiene (1977) (24)
- Novel chimeric scaffolds to extend the exploration of receptor space: hybrid beta-D-glucose-benzoheterodiazepine structures for broad screening. Effect of amide alkylation on the course of cyclization reactions. (2004) (24)
- An effective synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones (1993) (24)
- (+)-Sorangicin A: evolution of a viable synthetic strategy. (2011) (24)
- The photochemical decomposition of 1,4-s-tetrazine-15N2 (1977) (24)
- Total synthesis of architecturally complex indole terpenoids: strategic and tactical evolution (2017) (24)
- Polyene cyclizations to indole diterpenes. The first synthesis of (+)-emindole SA using a biomimetic approach (2000) (24)
- (+)-Trienomycins A, B, C, and F and (+)-Mycotrienins I and II: Relative and Absolute Stereochemistry (1996) (24)
- The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site (2020) (24)
- Total Synthesis of (−)-Enigmazole A (2015) (23)
- (R)-(+)- and (S)-(-)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl (binap) [Phosphine, [1,1′-binaphthalene]-2,2′-diylbis[diphenyl-, (R)- and (S)] (1999) (23)
- Indole diterpenoid synthetic studies. The total synthesis of (+)-nodulisporic acid F. (2006) (23)
- Design, synthesis, and biological evaluation of diminutive forms of (+)-spongistatin 1: lessons learned. (2011) (23)
- Infrared Spectrum of Two Fullerene Derivatives: C60O and C61H2 (1994) (23)
- Structure and low energy dynamics of solid C60 (1992) (23)
- Calyculin synthetic studies. 3. Enantiomeric purity determination for the C(26)–C(32) oxazole segment via the silks-odom 77Se NMR method (1994) (23)
- Intramolecular [2 + 2] photochemical cycloadditions. 3. Perhydrohistrionicotoxin synthetic studies: synthesis of spiro[4.5]decanones via intramolecular [2 + 2] photocycloaddition (1984) (23)
- Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group. (2017) (23)
- Fluorinated fullerenes: Synthesis and characterization (1992) (23)
- High resolution X-ray scattering study of the multiply reentrant polar mesogen DB9ONO2 (1986) (23)
- Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1–dependent (2010) (23)
- A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model (2018) (23)
- A common strategy for construction of the paniculides (A-C): total synthesis of paniculide A (1981) (23)
- SOSIP Changes Affect Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Conformation and CD4 Engagement (2018) (23)
- Phyllanthoside-phyllanthostatin synthetic studies. 9. Total syntheses of (-)-phyllanthostatin 1, (+)-phyllanthostatin 2, and (+)-phyllanthostatin 3 (1991) (23)
- Spirastrellolide B: construction of the C(26)-C(40) northern hemisphere and a related [5,5,7]-bis-spiroketal analogue. (2012) (23)
- A Cavaet on the Swern Oxidation (1988) (22)
- Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins (2020) (22)
- Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues. (2004) (22)
- (+)-Rimocidin synthetic studies: construction of the C(1-27) aglycone skeleton. (2009) (22)
- The design, synthesis and validation of recoverable and readily reusable siloxane transfer agents for Pd-catalyzed cross-coupling reactions. (2013) (22)
- The solution structure of (+)-spongistatin 1 in DMSO. (2010) (22)
- Synthesis and biological evaluation of a spongistatin AB-spiroketal analogue. (2002) (22)
- An efficient asymmetric synthesis of the four stereoisomers of 3-hydroxyleucine (1993) (22)
- A First Generation Total Synthesis of (+)‐Salicylihalamide A. (2001) (21)
- Avermectin-milbemycin studies. 4. An expedient two-step preparation of p-hydroxybenzoates (1985) (21)
- Preparation, stereochemistry, and nuclear magnetic resonance spectroscopy of 4-hydroxy(acetoxy)bicyclo[5.1.0]octanes. Synthesis of (-)- and (.+-.)-8,8-dimethylbicyclo[5.1.0]oct-2-en-4-one (1982) (21)
- Total synthesis of (.+-.)-mycorrhizin A and (.+-.)-dechloromycorrhizin A (1982) (21)
- Unimolecular photodissociation of s-tetrazine and derivatives (1988) (21)
- New Mandelalides Expand a Macrolide Series of Mitochondrial Inhibitors. (2017) (21)
- An efficient, second-generation synthesis of the signature dioxabicyclo[3.2.1]octane core of (+)-sorangicin A and elaboration of the (Z,Z,E)-triene acid system. (2009) (21)
- Brain-penetrant tetrahydronaphthalene thromboxane A2-prostanoid (TP) receptor antagonists as prototype therapeutics for Alzheimer's disease. (2012) (21)
- A caveat on the Sharpless asymmetric dihydroxylation (1995) (20)
- High-resolution optical spectroscopy and laser isotope enrichment of matrix-isolated s-tetrazine in argon (1977) (20)
- Total synthesis of (-)-aplaminal. (2008) (20)
- Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes. (2005) (20)
- Total Synthesis of (-)-Nahuoic Acid Ci (Bii). (2017) (20)
- Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C7 hydroxyl, and the lactone. (2005) (20)
- Two-dimensional infrared investigation of N-acetyl tryptophan methyl amide in solution. (2007) (20)
- Anion relay chemistry extended. Synthesis of a gorgonian sesquiterpene. (2007) (20)
- Chemical and Behavioral Complexity in Mammalian Chemical Communication Systems: Guinea Pigs ( Cavia Porcellus ), Marmosets ( Saguinus Fuscicollis ) and Humans ( Homo Sapiens ) (1977) (20)
- Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands (2020) (20)
- Total synthesis of (.+-.)-breynolide: an aglycon derivative of a potent, orally active hypocholesterolemic agent (1991) (20)
- Bifunctional molecular linchpins: A three-component coupling protocol employing 2-bromoallyltrimethylsilane (2004) (19)
- A facile synthesis of simple tetronic acids and pulvinones (1980) (19)
- The Chemistry of the Akuammiline Alkaloids. (2016) (19)
- Validation of diethoxyphosphonate as an effective agent for charge transfer in Anion Relay Chemistry (ARC). (2012) (19)
- TOTAL SYNTHESIS OF (+)-TRIENOMYCINS A AND F (1995) (19)
- Organoselenium-induced ring closures: cyclization of dienes with "PhSeOH" to form cyclic ethers (1979) (19)
- (+)-Trienomycins A, B, and C : relative and absolute stereochemistry (1990) (19)
- In vitro and in vivo anticancer activity of (+)-spongistatin 1. (2011) (19)
- Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals. (2016) (19)
- Design, synthesis and evaluation of photoactivatable derivatives of microtubule (MT)-active [1,2,4]triazolo[1,5-a]pyrimidines. (2018) (19)
- Design and synthesis of nonpeptide peptidomimetic inhibitors of renin (1995) (19)
- Design, Synthesis, and Solution Structure of a Pyrrolinone-Based β-Turn Peptidomimetic (2000) (19)
- Calyculin synthetic studies. Stereoselective construction of the C(14)-C(25) spiroketal subunit (1991) (19)
- C71H2 cyclopropanes and annulenes: synthesis and characterization (1994) (19)
- Total synthesis of (+)-jatropholone A and B (1985) (18)
- PHOSPHONYLTRIETHYLAMMONIUM SALTS : NOVEL REACTIVE SPECIES FOR THE SYNTHESIS OF PHOSPHONATE ESTERS AND PHOSPHONONAMIDES (1995) (18)
- Synthetic Access to the Mandelalide Family of Macrolides: Development of an Anion Relay Chemistry Strategy. (2018) (18)
- Vinylogous Wolff rearrangement. 5. Mechanistic studies (1984) (18)
- (+)-Rimocidin synthetic studies. Construction of an advanced C(1-18) polyol fragment. (2003) (18)
- A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity (2019) (18)
- Di-Cysteine S,S-Tetrazine: A Potential Ultra-fast Photochemical Trigger to Explore the Early Events of Peptide/Protein Folding. (2012) (18)
- Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain (2008) (18)
- Design, synthesis, and photochemical validation of peptide linchpins containing the S,S-tetrazine phototrigger. (2012) (18)
- Synthesis of geiparvarin: a novel antitumor agent possessing a 3(2H)-furanone ring (1980) (18)
- A New End Game for Aphidicolin (1988) (18)
- Indole-diterpene synthetic studies: 4. A stereocontrolled, second generation synthesis of (−)-paspaline (1988) (17)
- Recyclable Polystyrene-Supported Siloxane-Transfer Agent for Palladium-Catalyzed Cross-Coupling Reactions (2014) (17)
- Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: the confounding effects of DTT and cysteine in biological assays. (2007) (17)
- Total Synthesis of the Marine Phosphomacrolide, (-)-Enigmazole A, Exploiting Multicomponent Type I Anion Relay Chemistry (ARC) in Conjunction with a Late-Stage Petasis-Ferrier Union/Rearrangement. (2018) (17)
- Hemi-phorboxazole a: structure confirmation, analogue design and biological evaluation. (2009) (17)
- A convenient preparation of 4- and 5-substituted cyclopentenones: a short synthesis of methylenomycin B (1987) (17)
- Organic syntheses : an annual publication of satisfactory methods for the preparation of organic chemicals (1954) (17)
- Stereospecific synthesis of β-d-allopyranosides by dihydroxylation of β-d-erythro-2,3-dideoxyhex-2-enopyranosides (2001) (17)
- Design, synthesis, and evaluation of azepine-based cryptophycin mimetics (2003) (17)
- Mass spectrometric investigation of polyfluorinated C60. Evidence for the existence of C60F2n (n = 0–30) (1993) (17)
- DESIGN, SYNTHESIS, AND EVALUATION OF A PYRROLINONE-PEPTIDE HYBRID LIGAND FOR THE CLASS II MHC PROTEIN HLA-DR1 (1998) (17)
- Lewis acid promoted decomposition of unsaturated .alpha.-diazo ketones. 3. Stereochemical consequences of polyolefinic cyclizations initiated by the .alpha.-diazo ketone functionality (1981) (17)
- Type II Anion Relay Chemistry: Conformational Constraints To Achieve Effective [1,5]-Vinyl Brook Rearrangements. (2017) (17)
- A vinylogous Wolff rearrangement; copper sulphate-catalysed decomposition of unsaturated diazomethyl ketones (1974) (17)
- Non-Naturally Occurring Small Molecule Microtubule-Stabilizing Agents: A Potential Tactic for CNS-Directed Therapies. (2017) (17)
- Avermectin-milbemycin studies. 2. An efficient chemical degradation of avermectin b1a (1985) (16)
- SmI(2)-promoted oxidation of aldehydes in the presence of electron-rich heteroatoms. (2002) (16)
- Structure-based design and synthesis of HIV-1 protease inhibitors employing beta-D-mannopyranoside scaffolds. (2002) (16)
- Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains. (2006) (16)
- Diversity-oriented synthesis of polyketide natural products via iterative chemo- and stereoselective functionalization of polyenoates: development of a unified approach for the C(1-19) segments of lituarines A-C. (2005) (16)
- A new approach to simple cyclopentenones: Application to the synthesis of dihydro and cis-jasmone. (1975) (16)
- Quadrone structural and synthetic studies. Total synthesis of natural (-)-quadrone, the (+)-enantiomer, and the racemate. Conformational analysis, circular dichroism, and determination of absolute stereochemistry (1991) (16)
- Paclitaxel C-10 carbamates: potential candidates for the treatment of neurodegenerative tauopathies. (2007) (16)
- Hexagonal order in some mesophases of hexacyclen derivatives (1992) (16)
- Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir. (2021) (16)
- Stereochemical consequences of the vinylogous Wolff rearrangement (1976) (16)
- Rapamycin synthetic studies. 1. Construction of the C(27)-C(42) subunit (1994) (15)
- Design and synthesis of potent cystine-free cyclic hexapeptide agonists at the human urotensin receptor. (2006) (15)
- A scalable route to trisubstituted (E)-vinyl bromides. (2005) (15)
- Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype. (2008) (15)
- (+)-Phorboxazole A synthetic studies. Identification of a series of highly cytotoxic C(45-46) analogues. (2005) (15)
- Indole-Diterpene Synthetic Studies.: 3. A Unified Synthetic Strategy For The Simple Indole Tremorgens (1988) (15)
- Structure of Discotic Liquid-Crystalline Compounds at the Air-Water-Interface (1997) (15)
- Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics. (2005) (15)
- Furaquinocins A-G: relative and absolute stereochemistry (1992) (15)
- Indole‐Diterpene Synthetic Studies: Total Synthesis of (−)‐21‐Isopentenylpaxilline (2003) (15)
- Total synthesis of (+)-phyllanthoside (1987) (15)
- The major volatile constituents of the scent mark of a South American primateSaguinus fuscicollis, Callithricidae (2004) (15)
- Perineal scent gland of wild and domestic guinea pigs (1979) (15)
- Facile Assembly of 2,4-Orthogonally-Functionalized Oxazoles: Useful Bidirectional Linchpins (2001) (15)
- Total Synthesis of (−)-Secu’amamine A Exploiting Type II Anion Relay Chemistry (2015) (15)
- Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor. (2008) (15)
- Synthesis of(±)-descarboxylquadrone (1982) (15)
- Phase Diagram of Hexa-N-Alkylthiotriphenylenes (1993) (15)
- The major volatile constituents of the marmoset (Saguinus fuscicollis) scent mark (1976) (15)
- Long-range anion relay chemistry (LR-ARC): a validated ARC tactic. (2012) (15)
- A Small-Molecule CD4-Mimetic Compound Protects Bone Marrow–Liver–Thymus Humanized Mice From HIV-1 Infection (2018) (15)
- Iodine monobromide (IBr) at low temperature: A superior protocol for diastereoselective cyclizations of homoallylic carbonates (1992) (14)
- Design, synthesis, and biological evaluation of EF- and ABEF- analogues of (+)-spongistatin 1. (2010) (14)
- An enantioselective total synthesis of (−)-talaromycins A and B (1984) (14)
- Absolute stereochemistries and total synthesis of (+)/(−)-macrosphelides, potent, orally bioavailable inhibitors of cell–cell adhesion (2005) (14)
- A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains (1997) (14)
- Y-alkylation of lithium dienolates derived from 3(2h)-furanones and related α, β-unsaturated carbonyl compounds (1978) (14)
- Development of an Effective Scalable Enantioselective Synthesis of the HIV-1 Entry Inhibitor BNM-III-170 as the Bis-Trifluoroacetate Salt. (2019) (14)
- Total synthesis of (±)-desepoxy-4,5-didehybromethylenomycin A (1981) (14)
- Synthesis and biological evaluation of phorboxazole congeners leading to the discovery and preparative-scale synthesis of (+)-chlorophorboxazole a possessing picomolar human solid tumor cell growth inhibitory activity. (2008) (14)
- Total synthesis of (-)-irciniastatin B and structural confirmation via chemical conversion to (+)-irciniastatin A (psymberin). (2012) (14)
- Fourier transform infrared study of two truxene-based discotic liquid crystals (1990) (14)
- Self-organization of discogenic molecules at the air-water interface (1992) (14)
- Design, Synthesis, and Crystal Structure of a Pyrrolinone-Based Peptidomimetic Possessing the Conformation of a β-Strand: Potential Application to the Design of Novel Inhibitors of Proteolytic Enzymes (1993) (14)
- Total Synthesis of (+)-Hitachimycin (1990) (14)
- Anomalous Epoxide Formation Upon Wittig Olefination With 1-Iodoethyl Triphenylphosphonium Ylide (1998) (14)
- Brain‐Penetrant Triazolopyrimidine and Phenylpyrimidine Microtubule Stabilizers as Potential Leads to Treat Human African Trypanosomiasis (2018) (14)
- Evolution of Anion Relay Chemistry: Construction of Architecturally Complex Natural Products. (2020) (13)
- Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus. (2018) (13)
- Consecutive processes in the photolysis of dimethyl-s-tetrazine molecules in the vapor phase (1980) (13)
- Asymmetric synthesis of the anticoccidial antibiotic diolmycin A1. Determination of absolute stereochemistry (1993) (13)
- Total Synthesis of (-)-Nodulisporic Acids D, C, and B: Evolution of a Unified Synthetic Strategy. (2018) (13)
- Design and synthesis of a potent phorboxazole C(11-15) acetal analogue. (2006) (13)
- Synthetic strategies towards the total synthesis of phyllanthocin and breynolide. Application of stereochemically linear and convergent strategies (1999) (13)
- Catechol: A minimal scaffold for non-peptide peptidomimetics of the i + 1 and i + 2 positions of the beta-turn of somatostatin. (2006) (13)
- Aphidicolin synthetic studies: a stereocontrolled end game (1991) (13)
- Transport Characteristics of Peptidomimetics. Effect of the Pyrrolinone Bioisostere on Transport Across Caco-2 Cell Monolayers (1998) (13)
- An end-game strategy for construction of the G-H-I rings of penitrem D, A tremorgenic indole alkaloid (1993) (13)
- Complestatin synthetic studies; the effect of the amino acid configuration on peptide backbone conformation in the common western BCD macrocycle. (2004) (13)
- A versatile, efficient synthesis of (−)-(2S, 3R, 4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, the abbott pseudodipeptidyl insert (1990) (13)
- Nonpeptidal Peptidomimetics with a β‐D‐Glucose Scaffolding. A Partial Somatostatin Agonist Bearing a Close Structural Relationship to a Potent, Selective Substance P Antagonist. (1993) (12)
- A Formal Total Synthesis of (-)-Brevisamide. (2011) (12)
- Communication by scent in some Callitrichidae (Primates) - An interdisciplinary approach (1981) (12)
- Biomimetic Synthesis of Oleocanthal, Oleacein, and Their Analogues Starting from Oleuropein, A Major Compound of Olive Leaves. (2020) (12)
- The Crystal Structure of a Pyrrolinone−Peptide Hybrid Ligand Bound to the Human Class II MHC Protein HLA-DR1 (2000) (12)
- Replacement of Phe6, Phe7, and Phe11 of D-Trp8-somatostatin-14 with L-pyrazinylalanine. Predicted and observed effects on binding affinities at hSST2 and hSST4. An unexpected effect of the chirality of Trp8 on NMR spectra in methanol. (2005) (12)
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- Total synthesis of dechloromikrolin: A structural reassignment with biosynthetic implications (1987) (12)
- Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product--a further simplification of the lactone region. (2007) (12)
- Acid-catalysed decomposition of βγ-unsaturated diazomethyl ketones: a new cyclopentenone annelation (1975) (12)
- Avermectin-Milbemycin Studies. 3. Synthesis of a Milbemycin-Avermectin Hybrid (1985) (12)
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- Methodology for the preparation of olive oil open ring secoiridoids (2012) (11)
- Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation (2021) (11)
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- Total synthesis of (+)-18-epi-latrunculol A. (2013) (11)
- Two novel routes to spiro[3.4]octan-1-ones (1972) (11)
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- Design, Synthesis, and Application of Polymer-Supported Silicon-Transfer Agents for Cross-Coupling Reactions with Organolithium Reagents. (2017) (11)
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- Total synthesis of the pollen-growth inhibitor (-)-emeniveol. Assignment of absolute stereochemistry (1993) (10)
- Induction of a Tier-1-Like Phenotype in Diverse Tier-2 Isolates by Agents That Guide HIV-1 Env to Perturbation-Sensitive, Nonnative States (2017) (10)
- The intramolecular photorearrangement of cyclopentones (1969) (10)
- Spirastrellolide E: Synthesis of an advanced C(1)-C(24) southern hemisphere. (2015) (10)
- Total synthesis of (±)-xanthocidin and (±)-desdihydroxy-4,5-dihydroxanthocidin (1981) (10)
- The design, synthesis, and evaluation of two universal doxorubicin-linkers: preparation of conjugates that retain topoisomerase II activity. (2006) (10)
- Total Synthesis of (+)-Discodermolide (1995) (10)
- Resolution of 1,1'-BI-2-Naphthol [ 1,1'-Binaphthalene]-2,2'-diol ] (1999) (10)
- The design and synthesis of alanine-rich α-helical peptides constrained by an S,S-tetrazine photochemical trigger: a fragment union approach. (2014) (10)
- Structures of breynins A and B, architecturally complex orally active, hypocholesterolemic spiroketal glycosides (1992) (10)
- Total synthesis of (−)-gilmicolin (1985) (10)
- Regiospecific Methylation of Cyclopentenone Derivatives (1976) (10)
- Total Synthesis of (+)-18-epi-Latrunculol A: Development of a Synthetic Route (2014) (10)
- General Photoisomerization Approach to trans-Benzobicyclo[5.1.0]octenes: Synthetic and Mechanistic Studies (1994) (10)
- Computational Evaluation of HIV-1 gp120 Conformations of Soluble Trimeric gp140 Structures as Targets for de Novo Docking of First- and Second-Generation Small-Molecule CD4 Mimics (2016) (9)
- Small-Molecule CD 4 Mimics Interact with a Highly Conserved Pocket on HIV-1 gp 120 (2018) (9)
- Relative and absolute stereochemistry of the melanogenesis inhibitors OH-3984 K1 and K2. Partial synthesis from albocycline (1994) (9)
- Aminothienopyridazines as imaging probes of tau pathology: a patent evaluation of WO2013090497 (2014) (9)
- (+)-Mycotrienins I and II: Relative and Absolute Stereochemistry (1991) (9)
- Synthesis and binding affinities of novel SRIF-mimicking beta-D-glucosides satisfying the requirement for a pi-cloud at C1. (2005) (9)
- Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies. (2021) (9)
- Avermectin–milbemycin synthetic studies. Part 7. An approach to the southern hemisphere of milbemycin α1 (1992) (9)
- An Effective Bifunctional Aldehyde Linchpin for Type II Anion Relay Chemistry: Development and Application to the Synthesis of a C16–C29 Fragment of Rhizopodin (2015) (9)
- Design, synthesis, and evaluation of octahydropyranopyrrole-based inhibitors of mammalian ribonucleotide reductase. (2005) (9)
- Lewis acid promoted decomposition of unsaturated .alpha.-diazo ketones. 2. A new initiator for polyolefinic cation cyclization (1981) (9)
- Theoretical evaluation of stereoelectronic diastereofacial selectivity in the conjugate addition of cuprates to 5-substituted cyclopentenones (1988) (9)
- Total synthesis of (+)-hanegokedial (1983) (9)
- The total synthesis of (+)-payllanthostatin 2 (1987) (8)
- A facile route to paclitaxel C-10 carbamates. (2005) (8)
- A Mild, Diastereoselective Construction of Cyclic and Spirocyclic Ketals Employing a Tandem Photoisomerization/Cyclization Tactic (2014) (8)
- A Highly Efficient Synthetic Route to (-)-Furaquinocin C (2000) (8)
- Synthesis of a C(1)–C(23) Fragment for Spirastrellolide E: Development of a Mechanistic Rationale for Spiroketalization (2015) (8)
- Isotope-Labeled Aspartate Sidechain as a Non-Perturbing Infrared Probe: Application to Investigate the Dynamics of a Carboxylate Buried Inside a Protein. (2017) (8)
- Neutron-Scattering Study of Librations and Intramolecular Phonons in Rb_{2.6}K_{0.4}C_{60} (1994) (7)
- A concise route to the penitrem series of tremorgenic mycotoxins: preparation of an oxocane-fused indole (1988) (7)
- Preparation, stereochemistry, and nuclear magnetic resonance spectroscopy of methyl 1,3-dimethyl-2-oxocyclohexaneacetates and related derivatives (1977) (7)
- Evaluation of the cyclopentane-1,2-dione as a potential bio-isostere of the carboxylic acid functional group. (2014) (7)
- Design , synthesis and biological evaluation of small molecule inhibitors of CD 4-gp 120 binding based on virtual screening (2011) (7)
- Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 1. From nonpeptide peptidomimetics to nanotubes. (2010) (7)
- An Efficient Protocol for the Oxidative Hydrolysis of Ketone SAMP Hydrazones Employing SeO(2) and H(2)O(2) under Buffered (pH 7) Conditions. (2009) (7)
- Solid‐State Chemistry of Fullerene‐Based Materials (1992) (7)
- Microtubule-Stabilizing Agents for Alzheimer’s and Other Tauopathies (2016) (7)
- Evolution of a Synthetic Strategy: Total Synthesis of Jatrophone (1984) (7)
- Synthesis and Characterization of C60O, the First Fullerene Epoxide. (1992) (7)
- The identification, characterization and optimization of small molecule probes of cysteine proteases: experiences of the Penn Center for Molecular Discovery with cathepsin B and cathepsin L. (2009) (7)
- Total synthesis of (+)-dactylolide. (2002) (7)
- (+)-Thiazinotrienomycin E: Relative and absolute stereochemistry (1997) (7)
- Diffuse X-ray Scattering from Freely Suspended Strands of a Discotic Liquid Crystal (1995) (7)
- Profile Structures of Macromolecular Monolayers on Solid Substrates By X-Ray Interferometry/Holography (1991) (7)
- Tremorgenic Indole Alkaloids. 10. An Improved Asymmetric Synthesis of a Tricyclic Common Intermediate (1997) (7)
- Photochemical reactions of 3-substituted cyclopentenyl ketones (1974) (7)
- Isolation and structure determination of (+)-trienomycin F. an endgame synthetic strategy for the trienomycin family of antitumor antibiotics (1991) (7)
- Asymmetric Synthesis of Diethyl (R)‐(−)‐(1‐Amino‐3‐Methylbutyl)Phosphonate (2003) (7)
- Phyllanthoside-Phyllanthostatin synthetic studies. 6. An augmented spiroketalization tactic for the total synthesis of phyllanthocin (1989) (7)
- Preparation of some bicyclic ethers (1974) (6)
- Stabilizing the HIV-1 Envelope Glycoprotein State 2A Conformation (2020) (6)
- The first synthesis of a tricyclic homodetic peptide employing coordinated orthogonal protection (1996) (6)
- Langmuir Films of Amphiphilic Crown Ethers (1999) (6)
- The total synthesis of (–)-phyllanthostatin-1 (1987) (6)
- Multicomponent Linchpin Couplings of Silyl Dithianes via Solvent- Controlled Brook Rearrangement. (1997) (6)
- Design, Synthesis, and Evaluation of Irciniastatin Analogues: Simplification of the Tetrahydropyran Core and the C(11) Substituents (2016) (6)
- 13 C And 15N nuclear magnetic resonance parameters of ethyl diazoacetate (1977) (6)
- Solution and crystal structures of (+)-hitachimycin (stubomycin) (1990) (6)
- Fluorinated Fullerenes: Synthesis, Structure, and Properties. (1993) (6)
- α-Silyl Amides: Effective Bifunctional Lynchpins for Type I Anion Relay Chemistry. (2017) (6)
- Photochemistry of 6-propyl-2-cyclohexenone (1972) (6)
- Avermectin-milbemycin synthetic studies. 6. Stereoselective elaboration of the “southern hemisphere” oxahydrindene (1992) (6)
- Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues. (2011) (5)
- Development of an Efficient, Regio‐ and Stereoselective Route to Libraries Based on the β‐D‐Glucose Scaffold. (2001) (5)
- Structures of breynins A and B, architecturally complex, hypocholesterolemic spiroketal glycosides. A revised formulation of breynin B (1991) (5)
- Characterization of Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Variants Selected for Resistance to a CD4-Mimetic Compound (2022) (5)
- Small CD 4 Mimetics Prevent HIV-1 Uninfected Bystander CD 4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity (2016) (5)
- Smectic–smectic phase transitions in binary liquid‐crystalline mixtures of DB5–T8 (1990) (5)
- Pyrrolinone‐Based HIV Protease Inhibitors. Design, Synthesis, and Antiviral Activity: Evidence for Improved Transport. (1996) (5)
- SYNTHESIS OF THE FIRST TRICYCLIC HOMODETIC PEPTIDE. USE OF COORDINATED ORTHOGONAL DEPROTECTION TO ACHIEVE DIRECTED RING CLOSURE (1998) (5)
- A Conformational Phase Transition in a Langmuir Film of an Amphiphilic Azacrown (1998) (5)
- Asymmetric Synthesis of α-Aminophosphonates via Diastereoselective Addition of Lithium Diethyl Phosphite to Chelating Imines. (1995) (5)
- An NMR Study of He2 Inside C70. (1998) (5)
- Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro. (2020) (5)
- Electrochemical Intercalation of Lithium into Solid C60. (1992) (5)
- Synthesis, Structure and Superconducting Properties of Single-Phase Rb3C60. A New, Convenient Method for the Preparation of M3C60 Superconductors. (2010) (5)
- The β‐D‐Glucose Scaffold as a β‐Turn Mimetic (2010) (5)
- Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 2. Macrocyclic hexapyrrolinones. (2010) (5)
- Photoluminescence in solid films of C60 (1992) (5)
- Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18. (2011) (5)
- Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists. (2014) (5)
- Aphidicolin Synthetic Studies, 2.2D Nmr Analysis of Aphidicolin and Its Degradation Products 3α, 18-Dihydroxy-17-noraphidicolan- 16-one and 3α, 18-Isopropylidenedioxy- 17-noraphidicolan-16-one (1990) (4)
- .beta.,.gamma.-Unsaturated diazo ketones. A new initiator for polyolefinic cationic cyclization (1977) (4)
- A Scalable Synthesis of the Blue Fluorescent Amino Acid 4-Cyanotryptophan and the Fmoc Derivative: Utility Demonstrated with the Influenza M2 Peptide Tetramer. (2021) (4)
- Iodine Monobromide (IBr) at Low Temperature: Enhanced Diastereoselectivity in Electrophilic Cyclizations of Homoallylic Carbonates. (1993) (4)
- Acid-catalyzed rearrangements of tricyclo[4.3.2]Propellane derivatives (1984) (4)
- Phyllanthoside-Phyllanthostatin Synthetic Studies. Part 8. Total Synthesis of (+)-Phyllanthoside. Development of the Mitsunobu Glycosyl Ester Protocol. (1991) (4)
- Jatrophone, jatrophone derivatives, and analogs. Conformation and reactions with propanethiol (1983) (4)
- 6,7-Dihydrocyclopenta-1,3-Dioxin-5(4H)-One (2003) (4)
- The photochemistry of two rigid β,γ-cyclopropyl ketones, exo- and endo-tricyclo[3,2,1,02,4]octan-6-one (1975) (4)
- Evolution of the Petasis—Ferrier Union/Rearrangement Tactic: Construction of Architecturally Complex Natural Products Possessing the Ubiquitous cis‐2,6‐Substituted Tetrahydropyran Structural Element (2008) (4)
- Structure and Phase Transitions of the 6, 6-Cyclopropane Isomer of C_ {61} H_ {2} (2000) (4)
- Specific Noncovalent Interactions Determine Optimal Structure of a Buried Ligand Moiety: QM/MM and Pure QM Modeling of Complexes of the Small‐Molecule CD4 Mimetics and HIV‐1 gp120 (2018) (4)
- Global Increases in Human Immunodeficiency Virus Neutralization Sensitivity Due to Alterations in the Membrane-Proximal External Region of the Envelope Glycoprotein Can Be Minimized by Distant State 1-Stabilizing Changes (2021) (4)
- Enantioselective Synthesis of Diverse α‐Amino Phosphonate Diesters. (1996) (4)
- Biomimetic Total Synthesis of the Acat Inhibitor (+)‐Pyripyropene E (1996) (4)
- Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence (2020) (4)
- Anion Relay Chemistry: Development of an Effective Diastereoselective [3+2] Annulation Tactic Exploiting an Aldol/Brook Rearrangement/Cyclization Cascade. (2017) (4)
- Factors Controlling Reactivity in the Hydrogen Atom Transfer and Radical Addition Steps of a Radical Relay Cascade. (2019) (4)
- Organic letters: now in the 21st century. (2012) (4)
- 2‐Hydroxymethyl‐2‐Cyclopentenone (2003) (4)
- Primate chemical communication, part III Synthesis of the major volatile constituents of the marmoset (Saguinus fuscicollis) scent mark (1979) (4)
- 2,2-Dimethylcyclopent-4-ene-1,3-dione as a dienophile and a dipolarophile (1970) (4)
- Syn- andanti-phenylacetaldehyde oxime two novel testosterone-dependent mammalian metabolites (1977) (4)
- Skin surface microflora of the saddle-back tamarin monkey,Saguinus fuscicollis (1989) (4)
- Spin cast thin films of fullerenes and fluorinated fullerenes: Preparation and characterization by x‐ray reflectivity and surface diffuse x‐ray scattering (1992) (4)
- Total Synthesis of (+)‐Calyculin A and (‐)‐Calyculin B: Asymmetric Synthesis of the C(9—25) Spiroketal Dipropionate Subunit (I). (2000) (4)
- Optimization of Small Molecules That Sensitize HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity. (2019) (4)
- Total synthesis of (+)-phyllanthocindiol and (+)-phyllanthostatin 3 (1989) (4)
- Phosphonate Diester and Phosphonamide Synthesis. Reaction Coordinate Analysis by 31P NMR Spectroscopy: Identification of Pyrophosphonate Anhydrides and Highly Reactive Phosphonylammonium Salts. (1998) (4)
- VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry (2022) (4)
- Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. (2021) (4)
- Intramolecular photochemical oxetane formation in two β,γ-γ′,δ′-diunsaturated ketones (1976) (4)
- An efficient photochemical approach to the trans-bicyclo[5.1.0]octene ring system (1989) (3)
- Structures of (E,E)‐1,1'‐ethanediylidenebis(2,3‐dihydro‐1H‐indene), (E,E)‐1,1'‐ethanediylidenebis(1,2,3,4‐tetrahydronaphthalene) and (E,E)‐5,5'‐ethanediylidenebis(6,7,8,9‐tetrahydro‐5H‐benzocycloheptene) (1989) (3)
- Phosphonyltriethylammonium Salts: Novel Reactive Species for the Synthesis of Phosphonate Esters and Phosphonamides. (1995) (3)
- A Milestone Year for Organic Letters (2008) (3)
- The synthesis and biological evaluation of desepoxyisotedanolide and a comparison with desepoxytedanolide. (2015) (3)
- Relative and Absolute Stereochemistries and Total Synthesis of (+)-Macrosphelides A and B, Potent, Orally Bioavailable Inhibitors of Cell—Cell Adhesion. (1998) (3)
- Quadrone Structural and Synthetic Studies. Total Synthesis of Natural ( ‐)‐Quadrone, the (+)‐Enantiomer, and the Racemate. Conformational Analysis, Circular Dichroism, and Determination of Absolute Stereochemistry. (1991) (3)
- Total Syntheses of (+)-Peniciketals A-B and (-)-Diocollettines A Exploiting a Photoisomerization/Cyclization Union Protocol. (2021) (3)
- Hitachimycin (a.k.a. stubomycin): structural and synthetic studies (1989) (3)
- Chemical Synthesis of Diverse Phenolic Compounds Isolated From Olive Oils (2010) (3)
- Isomerization of 1,3‐Diphenyl‐2,2‐dichloroaziridine (1963) (3)
- Total Synthesis of (+)‐Zampanolide. (2002) (3)
- Design, synthesis and biological evaluation of a library of thiocarbazates and their activity as cysteine protease inhibitors. (2010) (3)
- Tuning the electronic transition energy of indole via substitution: application to identify tryptophan-based chromophores that absorb and emit visible light. (2021) (3)
- Merging Asymmetric [1,2]-Additions of Lithium Acetylides to Carbonyls with Type II Anion Relay Chemistry. (2019) (3)
- Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners. (2018) (3)
- Evolution of Multi-Component Anion Relay Chemistry (ARC): Construction of Architecturally Complex Natural and Unnatural Products (2009) (3)
- Total Synthesis of (+)‐Calyculin A and (‐)‐Calyculin B. (1999) (3)
- Total Synthesis of Immunosuppressants: Unified Strategies Exploiting Dithiane Couplings and σ‐Bond Olefin Constructions (1998) (3)
- Conjugated Addition to 2,2-Dimethyl-3(2h)-furanone: Support for the Baldwin Rules for Ring Closure (1978) (3)
- Functional and Highly Cross-Linkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation (2022) (3)
- Total Synthesis of (—)‐Nodulisporic Acid D. (2015) (3)
- 8:Stability of Pectin-Based Drug Delivery Systems (2012) (3)
- Total Synthesis of (‐)‐Calyciphylline N. (2014) (2)
- Synthesis and Assignment of Absolute Configuration of (-)-Oleocanthal: A Potent, Naturally Occurring Non-Steroidal Antiinflammatory and Antioxidant Agent Derived from Extra Virgin Olive Oils. (2006) (2)
- Applications of an Asymmetric (2 + 2)-Photocycloaddition. Total Synthesis of (-)-Echinosporin. Construction of an Advanced 11- Deoxyprostaglandin Intermediate. (1992) (2)
- Crystal and molecular structure of reductiomycin (1984) (2)
- Special Issue in Honor of Professor Susan Band Horwitz. (2018) (2)
- Total Synthesis of (+)-Phorboxazole A Exploiting the Petasis—Ferrier Rearrangement. (2002) (2)
- Synthesis of (+)-Tedanolide (2008) (2)
- Publisher Correction: The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions (2018) (2)
- Editorial 2006: exciting and challenging times for organic letters. (2006) (2)
- (+)-Hitachimycin : stereochemistry and conformational analysis (1992) (2)
- Preparation of [1‐(Methoxymethylcarbamoyl)ethyl] Phosphonic Acid Bis‐(2,2,2‐trifluoroethyl) Ester: A Useful Intermediate in the Synthesis of Z‐Unsaturated N‐Methoxy‐N‐Methylamides (2005) (2)
- The microtubule stabilizing agent discodermolide is also a powerful inducer of accelerated senescence (2004) (2)
- VE607 Stabilizes SARS-CoV-2 Spike In the “RBD-up” Conformation and Inhibits Viral Entry (2022) (2)
- Novel structures of a trans-cyclooctene and trans-fused cyclopropane generated via photoisomerization of a gem-dichlorocyclopropyl-benzocycloheptenone (1992) (2)
- Discodermolide and Taxol: A Synergistic Drug Combination in Human Carcinoma Cell Lines (2001) (2)
- HIV-1 Vpu restricts Fc-mediated effector functions in vivo (2022) (2)
- Total Syntheses of (+)-Trienomycins A and F via a Unified Strategy. (1997) (2)
- A Difluoromethylene Linchpin/Synthon: Application in Conjunction with Anion Relay Chemistry (ARC) Permits Ready Access to Diverse Difluoromethylene Scaffolds. (2020) (2)
- Total Synthesis of (‐)‐Cylindrocyclophane F. (1999) (2)
- Crystal and molecular structure of geiparvarin (1979) (2)
- Indole Diterpene Synthetic Studies: Development of a Second‐Generation Synthetic Strategy for (+)‐Nodulisporic Acids A and B. (2007) (2)
- The 2013 Benjamin Franklin Medal in Chemistry presented to Jerrold Meinwald, Ph.D (2015) (2)
- Organic Letters: celebrating 15 years. (2013) (2)
- Compressibility of C61D2 up to 1 GPa in the temperature range 175 - 345 K (1996) (2)
- Editorial 2004: The Next Five Years. (2004) (2)
- Evolution of Dithiane-Based Strategies for the Construction of Architecturally Complex Natural Products (2004) (2)
- Synthetic Routes to the Oxahydrindene Subunit of the Avermectin- Milbemycin Family of Antiparasitic Agents: A Review (1993) (2)
- Total Synthesis of (-)-Bastimolide A: A Showcase for Type I Anion Relay Chemistry. (2022) (2)
- Editorial: The First Three Years. (2002) (2)
- SERINC5 Restricts HIV-1 Infectivity by Promoting Conformational Changes and Accelerating Functional Inactivation of Env (2022) (2)
- The role of CuI in the siloxane-mediated Pd-catalyzed cross-coupling reactions of aryl iodides with aryl lithium reagents. (2020) (2)
- Chemoselective monoalkylation of 5-trifluoroacetamido- and 5-acetamido-1-pentanol derivatives via N,O-bisdeprotonation. Quantitation of evolved H2 as a probe of anion formation (1995) (2)
- Total Synthesis of the Latrunculins. (1992) (2)
- HIV-1 Envelope Glycoproteins Proteolytic Cleavage Protects Infected Cells from ADCC Mediated by Plasma from Infected Individuals (2021) (2)
- Binding Thermodynamics of a Small-Molecular-Weight CD4 Mimetic to HIV-1 gp120 (2008) (2)
- ortho‐TMS Benzaldehyde: An Effective Linchpin for Type II Anion Relay Chemistry (ARC). (2008) (2)
- Bifunctional Molecular Linchpins: A Three-Component Coupling Protocol Employing 2-Bromoallyltrimethylsilane. (2004) (2)
- Functional and Highly Crosslinkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation (2021) (2)
- Orientational Phase Transition in Na_{x}C_{60} (1 (1993) (2)
- General Photoisomerization Approach to trans-Benzobicyclo(5.1.0) octenes: Synthetic and Mechanistic Studies. (1995) (2)
- Structure-Based Design and Synthesis of HIV-1 Protease Inhibitors Employing β-D-Mannopyranoside Scaffolds. (2002) (2)
- Synthesis and rearrangement reactions of the first trans-homotropone (1992) (2)
- The First Design and Synthesis of a Steroidal Peptidomimetic. The Potential Value of Peptidomimetics in Elucidating the Bioactive Conformation of Peptide Ligands. (1993) (2)
- A Second‐Generation Synthesis of Polypyrrolinone Nonpeptidomimetics: Prelude to the Synthesis of Polypyrrolinones on Solid Support. (2000) (2)
- Total Synthesis of (-)-Furaquinocin C (IX). (1996) (2)
- Additions and Corrections - An Enantioselective Total Synthesis of (-)·Talaromycins A and B. (1985) (1)
- A Highly Efficient Synthetic Route to (‐)‐Furaquinocin C. (2000) (1)
- The Marine-Derived Macrolactone Mandelalide A Is an Indirect Activator of AMPK (2022) (1)
- Asymmetric Synthesis of the Anticoccidial Antibiotic Diolmycin A1. Determination of Absolute Stereochemistry. (1994) (1)
- Twenty Years of Organic Letters, A Look Back...and Forward. (2018) (1)
- Long Duration Variability and Spectrum of Mrk 421 (2008) (1)
- Synthesis of (+)-Lyconadin A (2007) (1)
- Polyene Cyclizations to Indole Diterpenes. The First Synthesis of (+)-Emindole SA Using a Biomimetic Approach. (2001) (1)
- Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure–Activity Insights (2022) (1)
- Total Synthesis of (+)‐Calyculin A (Ia) and (‐)‐Calyculin B (Ib): Cyanotetraene Construction, Asymmetric Synthesis of the C(26—37) Oxazole, Fragment Assembly, and Final Elaboration. (2000) (1)
- Total Synthesis of (‐)‐Aplaminal. (2009) (1)
- HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates. (2021) (1)
- An enantioselective total synthesis of (-)-talaromycins A and B (2002) (1)
- Erratum: Molecular docking of cathepsin l inhibitors in the binding site of papain (Journal of Chemical Information and Modeling (2008) 48 (1464-1472)) (2010) (1)
- (+)‐Trienomycins A, B, and C: Relative and Absolute Stereochemistry (1991) (1)
- Evolution of a Synthetic Strategy, Part II: Total Synthesis of (-)-Casbene and (-)-Bertyadionol (1989) (1)
- Review of Supporting Information at Organic Letters. (2015) (1)
- Total Synthesis of (‐)‐Kendomycin (I) Exploiting a Petasis—Ferrier Rearrangement/Ring‐Closing Olefin Metathesis Synthetic Strategy. (2005) (1)
- Indole-Diterpene Synthetic Studies: Total Synthesis of (-)-21-Isopentenylpaxilline. (2004) (1)
- Assembly of (-)-Cylindrocyclophanes A and F via Remarkable Olefin Metathesis Dimerizations. (2000) (1)
- Synthesis of (-)-Kendomycin (2005) (1)
- Design and Synthesis of a Tetrahydropyran‐Based Inhibitor of Mammalian Ribonucleotide Reductase. (1999) (1)
- Cryo-EM Structures of HIV-1 trimer bound to CD4-mimetics M48U1 and BNM-III-170 adopt a CD4-bound open conformation (2020) (1)
- Convenient Wacker Oxidations with Substoichiometric Cupric Acetate. (1999) (1)
- The Lyconadins: Enantioselective Total Syntheses of (+)‐Lyconadin A and (‐)‐Lyconadin B. (2009) (1)
- Hemi-Phorboxazole A (I): Structure Confirmation, Analogue Design and Biological Evaluation (2010) (1)
- Total Syntheses of (-)-Macrolactin A, (+)-Macrolactin E, and (-)-Macrolactinic Acid: An Exercise in Stille Cross-Coupling Chemistry. (1998) (1)
- A new photochemical reaction of cyclopentenones (1971) (1)
- Lessons Learned from Laboratory Vacuum Pump Exhaust Explosion: Discussion and Preventative Strategies (2021) (1)
- A General, Convergent Strategy for the Construction of Indolizidine Alkaloids: Total Syntheses of (‐)‐Indolizidine 223AB (I) and Alkaloid (‐)‐205B (II). (2006) (1)
- Crystal and molecular structure of hydroxyjatrophone C (1985) (1)
- Total Synthesis of the Neotropical Poison‐Frog Alkaloid (‐)‐205B. (2005) (1)
- (+)‐Phorboxazole A Synthetic Studies. A Highly Convergent, Second Generation Total Synthesis of (+)‐Phorboxazole A. (2006) (1)
- Synthesis of Tedanolide and 13-Deoxytedanolide. Assembly of a Common C(1)—C(11) Subtarget. (2000) (1)
- Update on Data Standards at Organic Letters. (2018) (1)
- Phyllanthoside‐Phyllanthostatin Synthetic Studies. Part 9. Total Syntheses of (‐)‐Phyllanthostatin 1, (+)‐Phyllanthostatin 2, and (+)‐ Phyllanthostatin 3. (1991) (1)
- An Efficient Asymmetric Synthesis of the Four Stereoisomers of 3‐ Hydroxyleucine. (1993) (1)
- A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model (2018) (1)
- SmI2-Promoted Oxidation of Aldehydes in the Presence of Electron-Rich Heteroatoms. (2003) (1)
- Phyllanthoside-Phyllanthostatin Synthetic Studies. Part 7. Total Synthesis of (+)-Phyllanthocin and (+)-Phyllanthocindiol. (1991) (1)
- Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity (2023) (1)
- Structure and Bonding in Alkali‐Metal‐Doped C60. (1991) (1)
- Chapter 11 – Microtubule Stabilization (2016) (1)
- Editorial 2003: Year Four. (2003) (1)
- Total Synthesis of (.+‐.)‐Breynolide, an Aglycon Derivative of the Orally Active Hypocholesterolemic Agent Breynin A. (1993) (1)
- HIV-1 Envelope Glycoprotein Cell Surface Localization Is Associated with Antibody-Induced Internalization (2021) (1)
- X-Ray Diffraction Studies of Protein Monolayers Bound to Self-Assembled Monolayers (1989) (1)
- Aphidicolin Synthetic Studies: A Stereocontrolled End Game. (1991) (1)
- Investigation of an antibody-ligase. Evidence for strain-induced catalysis. (2003) (1)
- Phorboxazole Synthetic Studies. Part 2. Construction of a C(20—28) Subtarget, a Further Extension of the Petasis—Ferrier Rearrangement. (1999) (0)
- Conformational Dynamics of Single HIV-1 Envelope Proteins on the Surface of Native Virions (2015) (0)
- Synthesis of the First Tricyclic Homodetic Peptide. Use of Coordinated Orthogonal Deprotection to Achieve Directed Ring Closure. (1998) (0)
- Formal Total Synthesis of FK506 (I). Concise Construction of the C(10)‐ C(34) Segment (II) via an Effective Coupling Tactic. (1994) (0)
- Synthesis of Prototypical Fullerene Cyclopropanes and Annulenes. Isomer Differentiation via NMR and UV Spectroscopy. (1995) (0)
- Design, Synthesis and Biological Evaluation of EF- and ABEF-Analogs of (+)-Spongistatin 1 (2010) (0)
- A Scalable Route to Trisubstituted (E)‐Vinyl Bromides. (2005) (0)
- Total Syntheses of (+)‐Zampanolide (I) and (+)‐Dactylolide (II) Exploiting a Unified Strategy. (2003) (0)
- 1,2‐Methanobuckminsterfullerene (C61H2), the Parent Fullerene Cyclopropane: Synthesis and Structure. (1993) (0)
- Total Synthesis of (‐)‐Okilactomycin. (2008) (0)
- Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120. (2023) (0)
- Structure of 1,1a,4,5,6,8,9,9a‐octahydro‐3‐methoxy‐1,1,2‐trimethyl‐(1aS‐trans)‐7H‐cyclopropa[3,4]cyclohept[1,2‐e]inden‐7‐one (1986) (0)
- Enantioretentive Alkylation of Oxazolidinone Aluminum Enolates with Epoxides: Preparation of Uncoded Homoserine Analogues. (1995) (0)
- Small Molecule HIV-1 Capsid Inhibitor Design using Hybrid Structure Based Methods (2011) (0)
- Triphenylene as a singlet sensitizer (1970) (0)
- Total Syntheses of (+)‐Paspalicine (VIII) and (+)‐Paspalinine (IX). (1991) (0)
- 2‐Trimethylsilyl‐1,3‐dithiane (2007) (0)
- Total Synthesis of (‐)‐Penitrem D. (2001) (0)
- Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC (2023) (0)
- The Daphniphyllum Alkaloids: Total Synthesis of (-)-Calyciphylline N. (2015) (0)
- Design, Synthesis, and Evaluation of Octahydropyranopyrrole‐Based Inhibitors of Mammalian Ribonucleotide Reductase. (2006) (0)
- brain-penetrant enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model. (2018) (0)
- Polymer-supported siloxane transfer agents: A green chemistry approach toward cross-coupling reactions (2014) (0)
- Total Syntheses of (+)‐Lyconadin A and (‐)‐Lyconadin B. (2007) (0)
- Novel Structures of a trans‐Cyclooctene and trans‐Fused Cyclopropane Generated via Photoisomerization of a gem‐ Dichlorocyclopropylbenzocycloheptenone. (1993) (0)
- A Versatile, Efficient Synthesis of (-)-(2S,3R,4S)-2-Amino-1- cyclohexyl-3,4-dihydroxy-6-methylheptane (I), the Abbott Pseudodipeptidyl Insert. (1991) (0)
- The Journal of Organic Chemistry Implements Brief Communications (2011) (0)
- Mimetic Sensitization of HIV-1-infected cells to 1 ADCC 2 3 4 (2017) (0)
- Abstract 2789: Interaction of (+)-discodermolide-Taxol hybrids with microtubules (2012) (0)
- BIS-β,β′-CONJUGATE ADDITION (1980) (0)
- The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions (2017) (0)
- Organic Letters Update. (2014) (0)
- Total Synthesis of the Pollen-Growth Inhibitor (-)-Emeniveol (I). Assignment of Absolute Stereochemistry. (1994) (0)
- Total Synthesis of the Marine Natural Product (-)-Clavosolide A: Showcase for the Petasis—Ferrier Union/Rearrangement Tactic. (2006) (0)
- Using Atomic Force Microscopy to Image Langmuir Blodgett Films of Disk Shaped Molecules (1994) (0)
- Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET (2019) (0)
- Synthesis of (+)-Psymberin (2009) (0)
- Structure and Mesophases of Hexacyclen Derivatives. (1992) (0)
- Neutron Scattering Studies of C61H2 (1994) (0)
- Anomalous Epoxide Formation Upon Wittig Olefination with 1-Iodoethyl Triphenylphosphonium Ylide. (1998) (0)
- Synthesis of (+)-Sorangicin A (2009) (0)
- Spongistatin Synthetic Studies. Part 2. Assembly of the C(18—28) Spiroketal. (1998) (0)
- Recyclable Polystyrene-Supported Siloxane-Transfer Agent for Palladium-Catalyzed Cross-Coupling Reactions. (2014) (0)
- The 2011 Benjamin Franklin Medal in Chemistry Presented to Kyriacos C. Nicolaou (2014) (0)
- Total Synthesis of (+)-18-epi-Latrunculol A (I). (2014) (0)
- Total synthesis of (-)-Irciniastatin B (2012) (0)
- Design and Synthesis of Potent Cystine‐Free Cyclic Hexapeptide Agonists at the Human Urotensin Receptor. (2006) (0)
- A Mild, Diastereoselective Construction of Cyclic and Spirocyclic Ketals Employing a Tandem Photoisomerization/Cyclization Tactic. (2015) (0)
- Total Synthesis of (−)‐Bastimolide A: A Showcase for Type I Anion Relay Chemistry (2022) (0)
- Total Synthesis of the Cytotoxic Macrocycle (+)‐Hitachimycin. (1993) (0)
- Diversity‐Oriented Synthesis of 2,4,6‐Trisubstituted Piperidines via Type II Anion Relay Chemistry. (2011) (0)
- Correction for Fricke et al., “Human Cytosolic Extracts Stabilize the HIV-1 Core” (2017) (0)
- Peptide Bond Formation via Catalytic Antibodies: Synthesis of a Novel Phosphonate Diester Hapten. (2010) (0)
- The Spongistatins: Architecturally Complex Natural Products. Part 1. A Formal Synthesis of (+)-Spongistatin 1 by Construction of an Advanced ABCD Fragment. (2001) (0)
- Construction of 5,6-Ring-Fused 2-Pyridones: An Effective Annulation Tactic Achieved in Water. (2010) (0)
- Synthesis of (-)-Okilactomycin (2008) (0)
- Nodulisporic Acid A Synthetic Studies. Part 2. Construction of an Eastern Hemisphere Subtarget (I). (2002) (0)
- (+)‐Phorboxazole A Synthetic Studies. Identification of a Series of Highly Cytotoxic C(45—46) Analogues. (2006) (0)
- Switching, Tunneling, and Superconductivity in Percolating Cluster Films (2014) (0)
- Editorial: The journal of organic chemistry implements brief communications (2011) (0)
- Facile Assembly of 2,4-Orthogonally-Functionalized Oxazoles: Useful Bidirectional Linchpins. (2002) (0)
- Rapamycin Synthetic Studies. Part 2. Elaboration of the C(10)-C(26) Perimeter. (1994) (0)
- Rapamycin Synthetic Studies. Part 1. Construction of the C(27)‐C(42) Subunit. (1994) (0)
- The 2008 Benjamin Franklin Medal in Chemistry is presented to Albert Eschenmoser, Dr. sc.nat (2011) (0)
- The interaction of spongistatin 1 with tubulin. (2022) (0)
- A Unified Total Synthesis of the Immunomodulators (‐)‐Rapamycin and (‐) ‐27‐Demethoxyrapamycin: Construction of the C(21‐42) Perimeters. (1997) (0)
- Synthesis of (+)-Phorboxazole A (2008) (0)
- The Spongistatins: Architecturally Complex Natural Products. Part 2. Synthesis of the C(29—51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2. (2001) (0)
- A Unified Total Synthesis of the Immunomodulators (-)-Rapamycin and (-) -27-Demethoxyrapamycin: Assembly of the Common C(1-20) Perimeter and Final Elaboration. (1997) (0)
- (+)-Trienomycins A (Ia), B (Ib), C (Ic), and F (Id) and (+)- Mycotrienins I (II) and II (Ie): Relative and Absolute Stereochemistry. (1997) (0)
- Erratum: Total synthesis of (+)-latrunculin B (Journal of the American Chemical Society (1986) 108, (2451-2453)) (1986) (0)
- Synthesis of Novel HIV-1 Protease Inhibitors Based on Carbohydrate Scaffolds. (2003) (0)
- Enantioselective Synthesis of (+)‐Kjellmanianone. (1991) (0)
- Synthesis and Rearrangement Reactions of the First trans‐Homotropone. (1993) (0)
- crystal structure of HIV-1 protease-hup (2004) (0)
- Phorboxazole Synthetic Studies. Part 1. Construction of a C(3—19) Subtarget. Exploiting an Extension of the Petasis—Ferrier Rearrangement. (1999) (0)
- Iodine Monobromide (IBr) at Low Temperature: A Superior Protocol for Diastereoselective Cyclization of Homoallylic Carbonates. (1993) (0)
- Total Synthesis of (‐)‐Salicylihalamide A and Related Congeners. (2002) (0)
- Spongistatin Synthetic Studies. Part 1. Construction of a C(29—48) Subtarget. (1998) (0)
- Relative and Absolute Stereochemistry of the Melanogenesis Inhibitors OH-3984 K1 and K2. Partial Synthesis from Albocycline. (1994) (0)
- A Tribute to Professor Kaoru Fuji on the Occasion of His 80th Birthday (2020) (0)
- Synthesis and in vitro Cancer Cell Growth Inhibitory Activity of Monocyclic Model Compounds Containing Spongistatin Triene Side‐Chains. (1998) (0)
- Synthesis of (+)-Scholarisine A (2012) (0)
- In search of an optimal silicon transfer agent for cross-coupling reactions (2018) (0)
- Design, Synthesis, and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors Possessing Augmented P2′ Side Chains. (2006) (0)
- An Effective Bifunctional Aldehyde Linchpin for Type II Anion Relay Chemistry: Development and Application to the Synthesis of a C16-C29 Fragment of Rhizopodin. (2016) (0)
- (+)‐Hitachimycin: Stereochemistry and Conformational Analysis. (1993) (0)
- Crystal and molecular structure of (±)-cyclomethylenomycinA (1978) (0)
- The NIH Public Access Mandate (2010) (0)
- Synthesis and Biological Evaluation of a Spongistatin AB‐Spiroketal Analogue. (2002) (0)
- Additions and Corrections - Total Synthesis of the Cytotoxic Macrocycle (+)-Hitachimycin (1993) (0)
- The 2010 Benjamin Franklin medal in chemistry presented to Joanne Stubbe (2014) (0)
- Correction. Total Synthesis of (+)-Latrunculin B (1986) (0)
- Tremorgenic Indole Alkaloids. Part 9. Asymmetric Construction of an Advanced F‐G‐H‐Ring Lactone Precursor for the Synthesis of Penitrem D. (2010) (0)
- Anion Relay Chemistry Extended. Synthesis of a Gorgonian Sequiterpene. (2008) (0)
- Total Synthesis of (+)‐Tedanolide. (2008) (0)
- SILICON-BASED CROSS COUPLING AGENTS (2013) (0)
- Nodulisporic Acid A (I) Synthetic Studies. Part 1. Overall Strategy and Construction of a Western Hemisphere Subtarget (II). (2002) (0)
- Indole Diterpenoid Synthetic Studies. Construction of the Heptacyclic Core of (-)-Nodulisporic Acid D (I). (2006) (0)
- Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes (2015) (0)
- Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity (2022) (0)
- Structure of HIV1 protease and AKC4p_133a complex. (2005) (0)
- Tremorgenic Indole Alkaloids. Part 10. An Improved Asymmetric Synthesis of a Tricyclic Common Intermediate (1997) (0)
- Design, Synthesis, and Evaluation of a Pyrrolinone—Peptide Hybrid Ligand for the Class II MHC Protein HLA-DR1 (1999) (0)
- Linking the Biological and Synthetic Worlds. (2015) (0)
- Indole Diterpene Synthetic Studies. Part 8. The Total Synthesis of (+)‐ Paspalicine and (+)‐Paspalinine. (1992) (0)
- Untitled Document (2001) (0)
- Complestatin Synthetic Studies: The Effect of the Amino Acid Configuration on Peptide Backbone Conformation in the Common Western BCD Macrocycle. (2004) (0)
- Chemoselective Monoalkylation of 5-Trifluoroacetamido- and 5-Acetamido- 1-pentanol Derivatives via N,O-Bisdeprotonation. Quantitation of Evolved H2 as a Probe of Anion Formation. (2010) (0)
- Lituarine Synthetic Studies. An Efficient, Stereocontrolled Construction of the Common C(7—19) Tricyclic Spiroketal Fragment (I). (2002) (0)
- Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines. (2022) (0)
- Farewell and Thanks. (2018) (0)
- Stereospecific Synthesis of β-D-Allopyranosides by Dihydroxylation of β-D-erythro-2,3-Dideoxyhex-2-enopyranosides. (2002) (0)
- Corrigendum to "The interaction of spongistatin 1 with tubulin" [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]. (2022) (0)
- PL-7 EVOLUTION OF THE PETASIS-FERRIER UNION/REARRANGEMENT TACTIC IN TOTAL SYNTHESIS (2006) (0)
- Data integrity. (2013) (0)
- Spongistatin Synthetic Studies. Part 3. Construction of the C(1—17) Spiroketal. (1998) (0)
- HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates. (2021) (0)
- Asymmetric construction of an advanced F-G-H-ring lactone precursor for the synthesis of penitrem D: tremorgenic indole alkaloids, part 9 (1995) (0)
- Total Synthesis of (+)‐Thiazinotrienomycin E. (2000) (0)
- Temperature Dependent Structural Studies of K- and RB- Doped C 60 (1992) (0)
- An Effective Synthesis of Scalemic 3,5,5-Trisubstituted Pyrrolin-4- ones. (1993) (0)
- A Small-Molecule CD4-mimetic Compound Protects BLT Humanized Mice from Human Immunodeficiency Virus Infection. (2018) (0)
- Keynote Speakers - Biographies (2018) (0)
- Synthesis and Characterization of the First C70O Epoxides. Utilization of 3He NMR in Analysis of Fullerene Derivatives. (1996) (0)
- Conformations of the Human Immunodeficiency Virus (HIV-1) Envelope Glycoproteins in Detergents and Styrene-Maleic Acid Lipid Particles (SMALPs) (2023) (0)
- Evolution of a Total Synthesis of (-)-Kendomycin Exploiting a Petasis—Ferrier Rearrangement/Ring-Closing Olefin Metathesis Strategy. (2006) (0)
- Evolution of a Gram‐Scale Synthesis of (+)‐Discodermolide. (2001) (0)
- Total Synthesis of (.+-.)-Breynolide: An Aglycon Derivative of a Potent, Orally Active Hypocholesterolemic Agent. (1991) (0)
- Correction for Lu et al., “Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands” (2020) (0)
- Syntheses of (-)-Oleocanthal (Vb), a Natural NSAID Found in Extra Virgin Olive Oil, the (-)-Deacetoxy-Oleuropein Aglycone (IX), and Related Analogues. (2008) (0)
- NEW APPROACH TO SIMPLE CYCLOPENTENONES. APPLICATION TO THE SYNTHESIS OF DIHYDRO- AND CIS-JASMONE (1976) (0)
- Avermectin‐Milbemycin Synthetic Studies. Part 7. An Approach to the Southern Hemisphere of Milbemycin α1. (1992) (0)
- Total Synthesis of (+)-Trienomycins A (XIIa) and F (XIIb). (1996) (0)
- (+)-Discodermolide: Total Synthesis, Construction of Novel Analogues, and Biological Evaluation (2008) (0)
- Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 Stereoisomer (2019) (0)
- Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy (2016) (0)
- A Second-Generation Synthesis of Scalemic 3,5,5-Trisubstituted Pyrrolin-4-ones: Incorporation of Functionalized Amino Acid Side- Chains. (1997) (0)
- WITHDRAWN: The 2011 Benjamin Franklin Medal in Chemistry presented to Kyriacos C. Nicolaou (2013) (0)
- Structure of HIV1 protease and hh1_173_3a complex. (2005) (0)
- Modular Synthesis of Fused Indole Derivatives (2006) (0)
- Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates (2022) (0)
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