Amy E Medlock | Academic Influence

Amy E Medlock's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Papers

Ferrochelatase at the millennium: structures, mechanisms and [2Fe-2S] clusters (152)
Substrate interactions with human ferrochelatase (68)
Identification of the Mitochondrial Heme Metabolism Complex (64)
A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase. (60)
A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase. (55)
Mitochondrial Atpif1 regulates heme synthesis in developing erythroblasts (53)
Human Coproporphyrinogen Oxidase Is Not a Metalloprotein* (52)
Product release rather than chelation determines metal specificity for ferrochelatase. (40)
From Synthesis to Utilization: The Ins and Outs of Mitochondrial Heme (38)
Glutamine via α-ketoglutarate dehydrogenase provides succinyl-CoA for heme synthesis during erythropoiesis. (32)
Thoughts on interactions between PGRMC1 and diverse attested and potential hydrophobic ligands (31)
Examination of the activity of carboxyl-terminal chimeric constructs of human and yeast ferrochelatases. (26)
Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis. (26)
Resonance Raman Spectra of Ferrochelatase Reveal Porphyrin Distortion upon Metal Binding (25)
A mouse model for South African (R59W) variegate porphyria: construction and initial characterization. (16)
Mitochondrial–nuclear heme trafficking in budding yeast is regulated by GTPases that control mitochondrial dynamics and ER contact sites (15)
Regulation of Mammalian Heme Biosynthesis (12)
Identification and characterization of solvent-filled channels in human ferrochelatase. (12)
The mitochondrial heme metabolon: Insights into the complex(ity) of heme synthesis and distribution. (12)
Mitochondrial-nuclear heme trafficking is regulated by GTPases in control of mitochondrial dynamics and ER contact sites. (9)
Corrigendum: Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts (5)
Insight into the Function of Active Site Residues in the Catalytic Mechanism of Human Ferrochelatase. (2)
Ironing out the distribution of [2Fe-2S] motifs in ferrochelatases (1)
The heme biosynthetic enzyme, 5-aminolevulinic acid synthase (ALAS), and GTPases in control of mitochondrial dynamics and ER contact sites, regulate heme mobilization to the nucleus (1)
Wild type human ferrochelatase crystallized with MnCl2 (1)
The Development and Use of Case Studies (1)
Evaluation of a Gender Gap in Student Academic Performance of an Integrated Hybrid Curriculum (0)
M76H variant of human ferrochelatase (0)
Heme biosynthesis and trafficking (0)
Managing Micronutrient Nutrition: The Vitamin B12 Exemplar (0)
Erratum: Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts (Nature (2012) 491 (608-612) doi:10.1038/nature11536) (0)
Mitochondrial Contact Site and Cristae Organizing System (MICOS) Machinery Supports Heme Biosynthesis by Enabling Optimal Performance of Ferrochelatase (0)
Human ferrochelatase with Mn and deuteroporphyrin bound (0)
E343D/F110A Double mutant of human ferrochelatase (0)
Human ferrochelatase with Cd and protoporphyrin IX bound (0)
Decision letter: In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases (0)
1.7 angstrom structure of human ferrochelatase variant R115L (0)
E343D variant of human ferrochelatase (0)
Hg and protoporphyrin bound Human Ferrochelatase (0)
F110A variant of human ferrochelatase with protoheme bound (0)
Wild type human ferrochelatase crystallized with ammonium sulfate (0)
S197C variant of human ferrochelatase (0)
Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys (0)
H240A variant of human ferrochelatase (0)
Crystal structure of human ferrochelatase mutant with His 341 replaced by Cys (0)
Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase (0)
F337R variant of human ferrochelatase (0)
Cofactors and Coenzymes | Porphyrin Metabolism in Eukaryotes (0)
Human Ferrochelatase with deuteroporphyrin and Ni Bound (0)
Cofactors and Coenzymes | Porphyrin Metabolism in Prokaryotes (0)
Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala (0)
2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound (0)
Just-in-Time Teaching (JiTT): An Active Learning Pedagogy to Study Concepts in Cell Biology (0)
Structure of human ferrochelatase variant E343K with protoporphyrin IX bound (0)
The immunometabolite itaconate inhibits heme synthesis and remodels cellular metabolism in erythroid precursors. (0)

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What Schools Are Affiliated With Amy E Medlock?

Amy E Medlock is affiliated with the following schools:

University of Georgia
Erskine College
Augusta University