Ana Belén Elgoyhen
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Argentinian molecular biologist
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Molecular Biology
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Biology
Ana Belén Elgoyhen's Degrees
- PhD Biological Sciences National University of Quilmes
- Bachelors Biological Sciences National University of Quilmes
Why Is Ana Belén Elgoyhen Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ana Belén Elgoyhen is an Argentine scientist, professor of pharmacology at the University of Buenos Aires and independent researcher of the National Scientific and Technical Research Council . She is internationally recognized for her contributions to the understanding of the molecular basis of hearing . Her work could be useful to treat auditory deficiencies and other hearing pathologies.
Ana Belén Elgoyhen's Published Works
Published Works
- α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells (1994) (812)
- α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells (2001) (681)
- Phantom percepts: Tinnitus and pain as persisting aversive memory networks (2011) (523)
- An integrative model of auditory phantom perception: Tinnitus as a unified percept of interacting separable subnetworks (2014) (309)
- Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. (1994) (295)
- Role of α9 Nicotinic ACh Receptor Subunits in the Development and Function of Cochlear Efferent Innervation (1999) (291)
- Mixed nicotinic–muscarinic properties of the α9 nicotinic cholinergic receptor (2000) (148)
- Developmental Regulation of Nicotinic Synapses on Cochlear Inner Hair Cells (2004) (145)
- α-RgIA: A Novel Conotoxin That Specifically and Potently Blocks the α9α10 nAChR†,‡ (2006) (144)
- alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors. (1995) (143)
- Alpha9 nicotinic acetylcholine receptors and the treatment of pain. (2009) (137)
- Tinnitus: perspectives from human neuroimaging (2015) (135)
- The α10 nicotinic acetylcholine receptor subunit is required for normal synaptic function and integrity of the olivocochlear system (2007) (121)
- A Novel α-Conotoxin, PeIA, Cloned from Conus pergrandis, Discriminates between Rat α9α10 and α7 Nicotinic Cholinergic Receptors* (2005) (105)
- Molecular cloning and chromosomal localization of the human alpha 7-nicotinic receptor subunit gene (CHRNA7). (1994) (105)
- A Point Mutation in the Hair Cell Nicotinic Cholinergic Receptor Prolongs Cochlear Inhibition and Enhances Noise Protection (2009) (104)
- High calcium permeability and calcium block of the α9 nicotinic acetylcholine receptor (2000) (102)
- Tinnitus: perspectives from human neuroimaging (2015) (102)
- The α9α10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations (2002) (98)
- The α9 Nicotinic Acetylcholine Receptor Shares Pharmacological Properties with Type A γ-Aminobutyric Acid, Glycine, and Type 3 Serotonin Receptors (1999) (93)
- Adaptive evolution in mammalian proteins involved in cochlear outer hair cell electromotility. (2006) (90)
- Stoichiometry of the α9α10 Nicotinic Cholinergic Receptor (2005) (88)
- Biophysical and pharmacological characterization of nicotinic cholinergic receptors in rat cochlear inner hair cells (2005) (85)
- Identification of the subunits of the nicotinic cholinergic receptors in the rat cochlea using RT-PCR and in situ hybridization. (1998) (85)
- Expression of nicotinic acetylcholine receptor mRNA in the adult rat peripheral vestibular system (1996) (84)
- Emerging pharmacotherapy of tinnitus (2011) (82)
- Current pharmacological treatments for tinnitus (2012) (82)
- Tinnitus and tinnitus disorder: Theoretical and operational definitions (an international multidisciplinary proposal). (2021) (81)
- The efferent medial olivocochlear-hair cell synapse (2012) (74)
- Cochlear hair cells: The sound‐sensing machines (2015) (73)
- Pharmacological approaches to the treatment of tinnitus. (2010) (72)
- Mixed nicotinic-muscarinic properties of the alpha9 nicotinic cholinergic receptor. (2000) (66)
- The nicotinic receptor of cochlear hair cells: a possible pharmacotherapeutic target? (2009) (62)
- Tinnitus: network pathophysiology-network pharmacology (2012) (61)
- Therapeutic Approaches to the Treatment of Tinnitus. (2019) (59)
- Direct Interaction of Serotonin Type 3 Receptor Ligands with Recombinant and Native α9α10-Containing Nicotinic Cholinergic Receptors (2003) (54)
- A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors. (2005) (53)
- The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations. (2002) (52)
- Alpha-RgIA: a novel conotoxin that specifically and potently blocks the alpha9alpha10 nAChR. (2006) (51)
- Enhancement of the Medial Olivocochlear System Prevents Hidden Hearing Loss (2018) (51)
- Trauma-Associated Tinnitus: Audiological, Demographic and Clinical Characteristics (2012) (50)
- Effects of Quinine, Quinidine, and Chloroquine on α9α10 Nicotinic Cholinergic Receptors (2005) (50)
- Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses (2013) (50)
- Short-Term Synaptic Plasticity Regulates the Level of Olivocochlear Inhibition to Auditory Hair Cells (2011) (49)
- Prevalence of GJB2 mutations and the del(GJB6-D13S1830) in Argentinean non-syndromic deaf patients (2005) (49)
- The voltage-gated potassium channel subfamily KQT member 4 (KCNQ4) displays parallel evolution in echolocating bats. (2012) (45)
- Emerging pharmacotherapy of tinnitus (2009) (44)
- Phylogenetic differences in calcium permeability of the auditory hair cell cholinergic nicotinic receptor (2012) (43)
- SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells (2009) (42)
- The alpha9 nicotinic acetylcholine receptor shares pharmacological properties with type A gamma-aminobutyric acid, glycine, and type 3 serotonin receptors. (1999) (40)
- Selective Attention to Visual Stimuli Using Auditory Distractors Is Altered in Alpha-9 Nicotinic Receptor Subunit Knock-Out Mice (2016) (36)
- Tracking the Molecular Evolution of Calcium Permeability in a Nicotinic Acetylcholine Receptor (2014) (35)
- Prestin and the cholinergic receptor of hair cells: Positively-selected proteins in mammals (2011) (31)
- Activity of nAChRs containing α9 subunits modulates synapse stabilization via bidirectional signaling programs (2009) (31)
- Direct interaction of serotonin type 3 receptor ligands with recombinant and native alpha 9 alpha 10-containing nicotinic cholinergic receptors. (2003) (30)
- GJB2 and GJB6 Genes: Molecular Study and Identification of Novel GJB2 Mutations in the Hearing-Impaired Argentinean Population (2009) (30)
- The α1 subunit of nicotinic acetylcholine receptors in the inner ear: transcriptional regulation by ATOH1 and co‐expression with the γ subunit in hair cells (2007) (29)
- Inhibition of the α9α10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-d-aspartate receptors (2007) (29)
- Block of the α9 nicotinic receptor by ototoxic aminoglycosides (2000) (29)
- Deletion of dopamine D2 receptors from parvalbumin interneurons in mouse causes schizophrenia-like phenotypes (2018) (28)
- The α9/α10-Containing Nicotinic ACh Receptor Is Directly Modulated by Opioid Peptides, Endomorphin-1, and Dynorphin B, Proposed Efferent Cotransmitters in the Inner Ear (2002) (28)
- Compartmentalization of antagonistic Ca2+ signals in developing cochlear hair cells (2018) (27)
- Activation of Presynaptic GABAB(1a,2) Receptors Inhibits Synaptic Transmission at Mammalian Inhibitory Cholinergic Olivocochlear–Hair Cell Synapses (2013) (26)
- Preventing presbycusis in mice with enhanced medial olivocochlear feedback (2020) (24)
- Purinergic Signaling Controls Spontaneous Activity in the Auditory System throughout Early Development (2020) (24)
- Distinct Evolutionary Trajectories of Neuronal and Hair Cell Nicotinic Acetylcholine Receptors (2019) (24)
- Differential Contribution of Subunit Interfaces to α9α10 Nicotinic Acetylcholine Receptor Function (2017) (23)
- Key roles of hydrophobic rings of TM2 in gating of the α9α10 nicotinic cholinergic receptor (2005) (23)
- Cholinergic Inhibition of Hair Cells (2011) (22)
- Strengthening of the Efferent Olivocochlear System Leads to Synaptic Dysfunction and Tonotopy Disruption of a Central Auditory Nucleus (2018) (22)
- Spectrin βV adaptive mutations and changes in subcellular location correlate with emergence of hair cell electromotility in mammalians (2017) (22)
- Towards a unification of treatments and interventions for tinnitus patients: The EU research and innovation action UNITI. (2021) (22)
- Reduction of Tinnitus Severity by the Centrally Acting Muscle Relaxant Cyclobenzaprine: An Open-Label Pilot Study (2012) (21)
- Short-term plasticity and modulation of synaptic transmission at mammalian inhibitory cholinergic olivocochlear synapses (2014) (20)
- Inner Ear Genes Underwent Positive Selection and Adaptation in the Mammalian Lineage. (2019) (20)
- Commentary: Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice (2018) (20)
- Morphine inhibits an α9-acetylcholine nicotinic receptor-mediated response by a mechanism which does not involve opioid receptors (2000) (19)
- Contralateral-noise effects on cochlear responses in anesthetized mice are dominated by feedback from an unknown pathway. (2012) (18)
- Effect of acute exposure to reduced atmospheric pressures on body weight, food intake and body composition of growing rats. (1985) (18)
- Identifying Tinnitus-Related Genes Based on a Side-Effect Network Analysis (2014) (18)
- Ryanodine is a Positive Modulator of Acetylcholine Receptor Gating in Cochlear Hair Cells (2007) (16)
- Inhibition of the alpha9alpha10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-D-aspartate receptors. (2007) (15)
- A Gain-of-Function Mutation in the α9 Nicotinic Acetylcholine Receptor Alters Medial Olivocochlear Efferent Short-Term Synaptic Plasticity (2018) (15)
- Performance of speech perception after cochlear implantation in DFNB1 patients (2009) (14)
- Key roles of hydrophobic rings of TM2 in gating of the alpha9alpha10 nicotinic cholinergic receptor. (2005) (14)
- (E)-3-Furan-2-yl-N-p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation. (2020) (13)
- Electrical Properties and Functional Expression of Ionic Channels in Cochlear Inner Hair Cells of Mice Lacking the α10 Nicotinic Cholinergic Receptor Subunit (2009) (13)
- Tinnitus Treatment with Oxytocin: A Pilot Study (2017) (13)
- Connexin 26 (GJB2) mutation in an Argentinean patient with keratitis-ichthyosis-deafness (KID) syndrome: a case report (2016) (12)
- α2* Nicotinic acetylcholine receptors influence hippocampus-dependent learning and memory in adolescent mice (2017) (12)
- Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness (2016) (12)
- Developmental Synaptic Changes at the Transient Olivocochlear–Inner Hair Cell Synapse (2019) (11)
- Grand Challenges for Global Brain Sciences (2016) (11)
- Relaxant effect of benzodiazepines on uterine rings isolated from estrogen-treated rats. (1990) (11)
- GJB2 and GJB6 Genetic Variant Curation in an Argentinean Non-Syndromic Hearing-Impaired Cohort (2020) (11)
- Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors. (2005) (10)
- Constitutive Expression of the α10 Nicotinic Acetylcholine Receptor Subunit Fails to Maintain Cholinergic Responses in Inner Hair Cells After the Onset of Hearing (2009) (10)
- Linopirdine Blocks α9α10-Containing Nicotinic Cholinergic Receptors of Cochlear Hair Cells (2004) (10)
- Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content. (2016) (10)
- Block of the alpha9 nicotinic receptor by ototoxic aminoglycosides. (2000) (10)
- Identification of four novel connexin 26 mutations in non-syndromic deaf patients: genotype–phenotype analysis in moderate cases (2013) (10)
- Unraveling the Molecular Players at the Cholinergic Efferent Synapse of the Zebrafish Lateral Line (2020) (9)
- Potassium channels as promising new targets for pharmacologic treatment of tinnitus: Can Internet-based ‘crowd sensing’ initiated by patients speed up the transition from bench to bedside? (2016) (9)
- Loss of Choline Agonism in the Inner Ear Hair Cell Nicotinic Acetylcholine Receptor Linked to the α10 Subunit (2020) (9)
- Pharmacological Approaches to Tinnitus Treatment (2011) (9)
- Editorial: Auditory Efferent System: New Insights from Cortex to Cochlea (2016) (8)
- Nicotinic Cholinergic Receptors (2005) (8)
- Functional Postnatal Maturation of the Medial Olivocochlear Efferent–Outer Hair Cell Synapse (2020) (8)
- Relaxant effects of benzodiazepines on isolated human umbilical arteries and veins (1993) (8)
- Different receptor subtypes mediate the dual presynaptic effects of 5-hydroxytryptamine on peripheral sympathetic neurones. (1989) (7)
- Serotonin uptake inhibitors and the prejunctional effects of serotonin on peripheral sympathetic nerves. (1986) (7)
- Efferent innervation and function (2010) (6)
- Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms. (2018) (6)
- The Hair Cell α9α10 Nicotinic Acetylcholine Receptor: Odd Cousin in an Old Family (2021) (6)
- Predicting pathogenicity for novel hearing loss mutations based on genetic and protein structure approaches (2022) (5)
- Erratum: Tinnitus: perspectives from human neuroimaging (Nature Reviews Neuroscience (2015) 16 (632-642)) (2015) (5)
- The α9α10 nicotinic acetylcholine receptor: a compelling drug target for hearing loss? (2022) (5)
- All Treatments in Tinnitus Are Experimental, Controversial, and Futuristic: A Comment on "Experimental, Controversial, and Futuristic Treatments for Chronic Tinnitus" by Folmer et al (2014). (2015) (5)
- Synaptic Contributions to Cochlear Outer Hair Cell Ca2+ Dynamics (2021) (4)
- Linopirdine blocks alpha9alpha10-containing nicotinic cholinergic receptors of cochlear hair cells. (2004) (4)
- Properties of mutated murine α4β2 nicotinic receptors linked to partial epilepsy (2008) (4)
- Benzodiazepines decrease the release of [3H]noradrenaline and of [3H]acetylcholine in the cat superior cervical ganglion (1989) (3)
- Treatment: Pharmacological, Repetitive Transcranial Magnetic Stimulation, Epidural Stimulation, and Deep Brain Stimulation (2012) (3)
- The Cholinergic Lateral Line Efferent Synapse: Structural, Functional and Molecular Similarities With Those of the Cochlea (2021) (2)
- Tinnitus and Coxsackie B infections: a case series. (2007) (2)
- Selectivity of (±)-citalopram at nicotinic acetylcholine receptors and different inhibitory mechanisms between habenular α3β4* and α9α10 subtypes (2019) (2)
- Positive spontaneous auditory phenomena (2013) (2)
- Auditory Efferent System: New Insights from Cortex to Cochlea (2016) (2)
- Cochlear efferent innervation: function, development and plasticity (2020) (2)
- Engineering olivocochlear inhibition to reduce acoustic trauma (2023) (1)
- Stephen F. Heinemann (1939–2014) (2014) (1)
- Functional expression and properties of a nicotinic &agr;9/5-HT3A chimeric receptor (2003) (1)
- The evolutionary tuning of hearing (2023) (1)
- A Latin American Perspective on Ion Channels (2016) (1)
- Synaptic contributions to cochlear outer hair cell Ca2+ homeostasis (2020) (1)
- Identification of four novel connexin 26 mutations in non-syndromic deaf patients: genotype–phenotype analysis in moderate cases (2013) (0)
- Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness (2016) (0)
- Off-label drugs investigated for the treatment of tinnitus (2010) (0)
- Mapping of the mouse alpha 9 acetylcholine receptor subunit (1997) (0)
- Ascorbic acid is a positive modulator of α9α10 nicotinic cholinergic receptors (2011) (0)
- Different Interactions of Citalopram with the Prejunctional Effects of Serotonin in Peripheral Tissues (1991) (0)
- Mitochondrial DNA variants in a cohort from Argentina with suspected Leber’s hereditary optic neuropathy (LHON) (2023) (0)
- Inhibitors of serotonin uptake and presynaptic serotonin effects in sympathetic neurons (1990) (0)
- Predicting pathogenicity for novel hearing loss mutations based on genetic and protein structure approaches (2022) (0)
- Efferent Innervation to the Cochlea (2018) (0)
- The α9α10 acetylcholine receptor: a non-neuronal nicotinic receptor. (2023) (0)
- Cloning and expression of ion channels from an acetylcholine-permeable receptor subunit (1995) (0)
- Receptor subtypes — Molecular biology and pharmacology (1994) (0)
- United States Patent ( 19 ) Elgoyhen et al . 54 METHODS OF IDENTIFYING MODULATORS OF ALPHA 9 , A NOVEL ACETYLCHOLINE-GATED ON CHANNEL RECEPTOR SUBUNIT 75 Inventors : (2017) (0)
- Electrical Stimulation of the Inferior Colliculus Lateral Olivocochlear System: Activation Via Modulation of Cochlear Afferent Response by the (2015) (0)
- Volume electron microscopy reveals age-related circuit remodeling in the auditory brainstem (2022) (0)
- New avenues for the treatment of tinnitus (0)
- Functional consequences of adaptive evolution of the mammalian α9α10 nicotinic receptor (2009) (0)
- The Remarkable Outer Hair Cell: Proceedings of a Symposium in Honour of W. E. Brownell (2023) (0)
- Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse (2018) (0)
- Beta - adrenergic stimulation and effects of benzodiazepines on rat isolated atria (1990) (0)
- Contralateral-noise effects on cochlear responses in anesthetized mice are 3 dominated by feedback from an unknown pathway 4 5 6 7 8 (2012) (0)
- Effects of benzodiazepines on β-adrenergic stimulation of rat isolated atria (1990) (0)
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