Anders Björklund

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Anders Björklund is affiliated with the following schools: Stockholm University, Uppsala University, Lund University, University of Copenhagen, Karolinska Institute

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Anders Björklund

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According to Wikipedia, Anders Björklund' is a Swedish neuroscientist and pioneer in the study of cell- and gene-based reparative and neuroprotective mechanisms in the brain. He has spent his academic career at Lund University in Sweden, as professor since 1983 and as senior professor at the Wallenberg Neuroscience Center since his formal retirement in 2012.

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Anders Björklund's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation (2008) (1630)
Dopamine neuron systems in the brain: an update (2007) (1542)
The organization of the ascending catecholamine neuron systems in the rat brain as revealed by the glyoxylic acid fluorescence method. (1974) (1134)
Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor (1987) (1039)
Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. (1986) (1036)
Cell replacement therapies for central nervous system disorders (2000) (957)
Direct conversion of human fibroblasts to dopaminergic neurons (2011) (745)
Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient (1999) (723)
Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System (2002) (682)
Characterization of Behavioral and Neurodegenerative Changes Following Partial Lesions of the Nigrostriatal Dopamine System Induced by Intrastriatal 6-Hydroxydopamine in the Rat (1998) (665)
L‐DOPA‐induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin‐ and glutamic acid decarboxylase mRNA (1998) (631)
Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats. (2007) (608)
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test (1995) (605)
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity (2013) (574)
Site-Specific Migration and Neuronal Differentiation of Human Neural Progenitor Cells after Transplantation in the Adult Rat Brain (1999) (563)
Prospects for new restorative and neuroprotective treatments in Parkinson's disease (1999) (558)
Reinnervation of the denervated striatum by substantia nigra transplants: Functional consequences as revealed by pharmacological and sensorimotor testing (1980) (546)
Mesencephalic dopamine neurons projecting to neocortex. (1974) (518)
Spatial learning and motor deficits in aged rats (1984) (513)
Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up. (1989) (511)
Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (1992) (506)
The organization of tubero-hypophyseal and reticulo-infundibular catecholamine neuron systems in the rat brain. (1973) (505)
Learning Deficit in BDNF Mutant Mice (1997) (493)
Distribution of vasoactive intestinal polypeptide in the rat and mouse brain (1979) (476)
Evidence for long‐term survival and function of dopaminergic grafts in progressive Parkinson's disease (1994) (457)
Dyskinesias following neural transplantation in Parkinson's disease (2002) (447)
Organization of catecholamine neurons projecting to the frontal cortex in the rat (1978) (425)
Long-Term rAAV-Mediated Gene Transfer of GDNF in the Rat Parkinson's Model: Intrastriatal But Not Intranigral Transduction Promotes Functional Regeneration in the Lesioned Nigrostriatal System (2000) (418)
Intracerebral neural implants: neuronal replacement and reconstruction of damaged circuitries. (1984) (418)
Topographic principles in the spinal projections of serotonergic and non-serotonergic brainstem neurons in the rat (1985) (413)
Septal transplants restore maze learning in rats with fornix-fimbria lesions (1982) (411)
l-DOPA-Induced Dyskinesia in the Intrastriatal 6-Hydroxydopamine Model of Parkinson's Disease: Relation to Motor and Cellular Parameters of Nigrostriatal Function (2002) (407)
Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation. (1983) (403)
Generation of induced neurons via direct conversion in vivo (2013) (385)
Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. (1995) (376)
Intrahippocampal septal grafts ameliorate learning impairments in aged rats. (1984) (364)
Short‐ and long‐term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease (1997) (360)
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease (2014) (348)
Mechanisms of action of intracerebral neural implants: studies on nigral and striatal grafts to the lesioned striatum (1987) (348)
Neurturin Exerts Potent Actions on Survival and Function of Midbrain Dopaminergic Neurons (1998) (346)
Efferent synaptic connections of grafted dopaminergic neurons reinnervating the host neostriatum: a tyrosine hydroxylase immunocytochemical study (1985) (344)
Regeneration of monoaminergic and cholinergic neurons in the mammalian central nervous system. (1979) (338)
Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats (1989) (335)
Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons (2009) (325)
Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions (1982) (317)
Plastic changes in the adrenergic innervation of the rat septal area in response to denervation. (1971) (315)
The adrenergic innervation of the rat thalamus as revealed by the glyoxylic acid fluorescence method (1974) (314)
Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease (2013) (311)
Topography of the monoamine neuron systems in the human brain as revealed in fetuses. (1973) (309)
Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: A new primate model of Parkinson's disease (2003) (305)
Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum (1984) (300)
Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. (2000) (298)
Organization of Catecholamine Neurons in the Rat Central Nervous System (1978) (296)
Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson’s Patients with Neural Transplants (2010) (296)
Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging (1992) (295)
Fluorescence histochemical and microspectrofluorometric mapping of dopamine and noradrenaline cell groups in the rat diencephalon. (1973) (295)
Localized striatal delivery of GDNF as a treatment for Parkinson disease (2004) (293)
Neural grafting in the mammalian CNS (1985) (290)
Evidence for a major spinal cord projection from the diencephalic A11 dopamine cell group in the rat using transmitter-specific fluorescent retrograde tracing (1979) (289)
Reinnervation of the partially deafferented hippocampus by compensatory collateral sprouting from spared cholinergic and noradrenergic afferents (1983) (285)
Sequential bilateral transplantation in Parkinson's disease: effects of the second graft. (1999) (284)
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons (2012) (272)
Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts (1990) (269)
NGF improves spatial memory in aged rodents as a function of age (1991) (268)
Cell transplantation in Parkinson's disease: how can we make it work? (2005) (268)
Delayed recovery of movement‐related cortical function in Parkinson's disease after striatal dopaminergic grafts (2000) (267)
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle (1999) (265)
Studies on Neuroprotective and Regenerative Effects of GDNF in a Partial Lesion Model of Parkinson's Disease (1997) (262)
Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by intrastriatal 6-hydroxydopamine in the rat (1996) (261)
Short-Term GDNF Treatment Provides Long-Term Rescue of Lesioned Nigral Dopaminergic Neurons in a Rat Model of Parkinson’s Disease (1996) (257)
Functional neural transplantation (1994) (255)
Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports. (2014) (254)
Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path (1976) (253)
Long-lasting selective depletion of brain serotonin by 5,6-dihydroxytryptamine. (1971) (252)
Origin and termination of the diencephalo-spinal dopamine system in the rat (1982) (251)
Regeneration of the septohippocampal pathways in adult rats is promoted by utilizing embryonic hippocampal implants as bridges (1981) (250)
Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis—II. Sensorimotor and learning impairments (1985) (248)
Endogenous Release of Neuronal Serotonin and 5‐Hydroxyindoleacetic Acid in the Caudate‐Putamen of the Rat as Revealed by Intracerebral Dialysis Coupled to High‐Performance Liquid Chromatography with Fluorimetric Detection (1988) (247)
Cell therapy in Parkinson's disease – stop or go? (2001) (246)
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. (2005) (243)
Subcortical projections to the prefrontal cortex in the rat as revealed by the horseradish peroxidase technique (1978) (243)
Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo (2012) (242)
Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats (1984) (242)
Identification of Dopaminergic Neurons of Nigral and Ventral Tegmental Area Subtypes in Grafts of Fetal Ventral Mesencephalon Based on Cell Morphology, Protein Expression, and Efferent Projections (2005) (241)
Regional differences in the regulation of dopamine and noradrenaline release in medial frontal cortex, nucleus accumbens and caudate-putamen: a microdialysis study in the rat (1992) (241)
Functional Activity of Substantia Nigra Grafts Reinnervating the Striatum: Neurotransmitter Metabolism and [14C]2‐Deoxy‐d‐glucose Autoradiography (1982) (240)
NGF receptor reexpression and NGF-mediated cholinergic neuronal hypertrophy in the damaged adult neostriatum (1989) (240)
Graft-induced behavioral recovery in an animal model of Huntington disease. (1986) (239)
Neural transplantation for the treatment of Parkinson's disease (2003) (238)
Converging projections from the mediodorsal thalamic nucleus and mesencephalic dopaminergic neurons to the neocortex in three species (1978) (237)
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia. (2008) (232)
Retrograde cell changes in medial septum and diagonal band following fimbria-fornix transection: Quantitative temporal analysis (1986) (232)
Intracerebral grafting of dissociated CNS tissue suspensions: a new approach for neuronal transplantation to deep brain sites (1981) (231)
Cholinergic septal grafts into the hippocampal formation improve spatial learning and memory in aged rats by an atropine-sensitive mechanism (1986) (230)
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain (2016) (230)
Growth of central catecholamine neurones into smooth muscle grafts in the rat mesencephalon. (1971) (230)
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons (2012) (230)
Dopaminergic innervation of the globus pallidus by collaterals from the nigrostriatal pathway (1979) (229)
In vivo release of DOPA and dopamine from genetically engineered cells grafted to the denervated rat striatum (1990) (227)
Identification and terminal distribution of the tubero-hypophyseal monoamine fibre systems in the rat by means of stereotaxic and microspectrofluorimetric techniques. (1970) (227)
Immortalized neural progenitor cells for CNS gene transfer and repair (1997) (225)
α-Synuclein–Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons (2012) (222)
Aberrant Sprouting and Downregulation of Tyrosine Hydroxylase in Lesioned Nigrostriatal Dopamine Neurons Induced by Long-Lasting Overexpression of Glial Cell Line Derived Neurotrophic Factor in the Striatum by Lentiviral Gene Transfer (2002) (222)
Protection of the Neostriatum against Excitotoxic Damage by Neurotrophin-Producing, Genetically Modified Neural Stem Cells (1996) (222)
Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism. (1983) (221)
Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts. (1996) (219)
Intracerebral grafting of neuronal cell suspensions. IV. Behavioural recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different forebrain sites. (1983) (219)
Striatal grafts in rats with unilateral neostriatal lesions—III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching (1988) (217)
Development and growth of axonal sprouts from noradrenaline and 5-hydroxytryptamine neurones in the rat spinal cord. (1971) (217)
Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cells implanted in different brain sites (1983) (217)
Evaluation of the effects of 5,7-dihydroxytryptamine on serotonin and catecholamine neurons in the rat CNS. (1973) (215)
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells (2009) (212)
A METHOD FOR DIFFERENTIATING DOPAMINE FROM NORADRENALINE IN TISSUE SECTIONS BY MICROSPECTROFLUOROMETRY (1968) (210)
Characterization of Lewy body pathology in 12‐ and 16‐year‐old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease (2010) (210)
Evidence for regenerative axon sprouting of central catecholamine neurons in the rat mesencephalon following electrolytic lesions. (1971) (210)
Spatial learning impairments in rats with selective immunolesion of the forebrain cholinergic system. (1992) (208)
Embryonic ventral mesencephalic grafts improve levodopa-induced dyskinesia in a rat model of Parkinson's disease. (2000) (208)
Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6‐hydroxydopamine lesioned adult rats (1992) (207)
Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6‐OHDA lesion model depends on the site of administration of the trophic factor (2000) (207)
Dopamine-containing cells in sympathetic ganglia. (1970) (207)
Regional incorporation and site-specific differentiation of striatal precursors transplanted to the embryonic forebrain ventricle (1995) (203)
Neural grafting in a rat model of huntington's disease: Progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting (1985) (198)
Serotonin Neuron Transplants Exacerbate l-DOPA- Induced Dyskinesias in a Rat Model of Parkinson's Disease (2007) (196)
Survival, Integration, and Differentiation of Neural Stem Cell Lines after Transplantation to the Adult Rat Striatum (1997) (196)
Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry (2002) (196)
Cross-species neural grafting in a rat model of Parkinson's disease (1982) (190)
Dopamine-containing neurons in the spinal cord: anatomy and some functional aspects. (1983) (189)
Autoregulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis (1987) (188)
Transplantation of Human Neural Progenitor Cells into the Neonatal Rat Brain: Extensive Migration and Differentiation with Long-Distance Axonal Projections (2002) (187)
Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro. (1988) (187)
Functional reactivation of the deafferented neostriatum by nigral transplants (1981) (185)
Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease. (1985) (185)
Selective Lesioning of the Basal Forebrain Cholinergic System by Intraventricular 192 IgG–saporin: Behavioural, Biochemical and Stereological Studies in the Rat (1995) (185)
Combined cholinergic and serotonergic denervation of the forebrain produces severe deficits in a spatial learning task in the rat (1988) (182)
NURR1 in Parkinson disease—from pathogenesis to therapeutic potential (2013) (178)
Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor. (1994) (176)
Early specification of striatal projection neurons and interneuronal subtypes in the lateral and medial ganglionic eminence (1998) (174)
Hippocampal Noradrenaline and Serotonin Release over 24 Hours as Measured by the Dialysis Technique in Freely Moving Rats: Correlation to Behavioural Activity State, Effect of Handling and Tail‐Pinch (1989) (174)
Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2 (2006) (172)
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum—I. Subcortical afferents (1988) (171)
Sequential Administration of GDNF into the Substantia Nigra and Striatum Promotes Dopamine Neuron Survival and Axonal Sprouting but Not Striatal Reinnervation or Functional Recovery in the Partial 6-OHDA Lesion Model (2000) (171)
Neural transplantation — an experimental tool with clinical possibilities (1991) (170)
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum—III. Efferent projecting graft neurons and their relation to host afferents within the grafts (1989) (167)
GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease. (2011) (167)
Host afferents into intrastriatal transplants of fetal ventral mesencephalon (1989) (166)
Innervation of embryonic hippocampal implants by regenerating axons of cholinergic septal neurons in the adult rat (1981) (165)
Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain. (2002) (163)
Anatomy of the dopaminergic neuron systems in the rat brain. (1978) (163)
Intrastriatal glial cell line-derived neurotrophic factor promotes sprouting of spared nigrostriatal dopaminergic afferents and induces recovery of function in a rat model of Parkinson's disease (1997) (162)
FETAL DOPAMINE-RICH MESENCEPHALIC GRAFTS IN PARKINSON'S DISEASE (1988) (162)
Projection neurons in fetal striatal transplants are predominantly derived from the lateral ganglionic eminence (1995) (161)
Glyoxylic acid condensation: a new fluorescence method for the histochemical demonstration of biogenic monoamines. (1973) (159)
The glyoxylic acid fluorescence histochemical method: a detailed account of the methodology for the visualization of central catecholamine neurons (1974) (159)
Enhanced graft survival in the hippocampus following selective denervation (1986) (158)
Reversal of age-dependent cognitive impairments and cholinergic neuron atrophy by NGF-secreting neural progenitors grafted to the basal forebrain (1995) (158)
Graft‐induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio (2011) (158)
Striatal grafts in rats with unilateral neostriatal lesions—I. Ultrastructural evidence of afferent synaptic inputs from the host nigrostriatal pathway (1988) (157)
In Vivo Protection of Nigral Dopamine Neurons by Lentiviral Gene Transfer of the Novel GDNF-Family Member Neublastin/Artemin (2000) (157)
Growth of vascular sympathetic axons into the hippocampus after lesions of the septo-hippocampal pathway: a pitfall in brain lesion studies (1978) (156)
Selective histochemical demonstration of dopamine terminal systems in rat di- and telecephalon: New evidence for dopaminergic innervation of hypothalamic neurosecretory nuclei (1984) (156)
Overexpression of Glial Cell Line-Derived Neurotrophic Factor Using a Lentiviral Vector Induces Time- and Dose-Dependent Downregulation of Tyrosine Hydroxylase in the Intact Nigrostriatal Dopamine System (2004) (155)
Classification of monoamine neurones in the rat mesencephalon: distribution of a new monoamine neurone system. (1971) (154)
Acetylcholine release in the rat hippocampus as studied by microdialysis is dependent on axonal impulse flow and increases during behavioural activation (1990) (153)
Neural grafting in a rat model of huntington's disease: Striosomal-like organization of striatal grafts as revealed by acetylcholinesterase histochemistry, immunocytochemistry and receptor autoradiography (1987) (151)
Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion (2008) (151)
CNS-derived neural progenitor cells for gene transfer of nerve growth factor to the adult rat brain: complete rescue of axotomized cholinergic neurons after transplantation into the septum (1995) (145)
Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of l-dopa using rAAV-mediated gene transfer (2002) (145)
Age-related impairments in spatial memory are independent of those in sensorimotor skills (1989) (144)
Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments (1990) (144)
GABA and neuropeptides in the CNS (1985) (142)
Behavioural effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease (2004) (140)
Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study (2015) (140)
Generation of DOPA-Producing Astrocytes by Retroviral Transduction of the Human Tyrosine Hydroxylase Gene:In VitroCharacterization andin VivoEffects in the Rat Parkinson Model (1996) (140)
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons (2013) (138)
Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model (1994) (138)
Incorporation and Glial Differentiation of Mouse EGF-Responsive Neural Progenitor Cells after Transplantation into the Embryonic Rat Brain (1998) (137)
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6‐hydroxydopamine lesions in a mouse model of Parkinson’s disease (2010) (135)
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain (2017) (134)
Intracerebral grafting of neuronal cell suspensions. V. Behavioural recovery in rats with bilateral 6-OHDA lesions following implantation of nigral cell suspensions. (1983) (134)
Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease (2001) (134)
Aged rats: recovery of motor impairments by intrastriatal nigral grafts. (1983) (134)
Study of the antidyskinetic effect of eltoprazine in animal models of levodopa‐induced dyskinesia (2013) (133)
Comparison of the behavioural and histological characteristics of the 6-OHDA and α-synuclein rat models of Parkinson's disease (2012) (132)
Survival, growth and function of dopaminergic neurons grafted to the brain. (1987) (131)
Striatal grafts in rats with unilateral neostriatal lesions—II. In vivo monitoring of gaba release in globus pallidus and substantia nigra (1988) (129)
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease (2010) (128)
Functional correlates of compensatory collateral sprouting by aminergic and cholinergic afferents in the hippocampal formation (1983) (128)
Regeneration of central serotonin neurons after axonal degeneration induced by 5,6-dihydroxytryptamine. (1973) (128)
Serotonin Neuron Loss and Nonmotor Symptoms Continue in Parkinson’s Patients Treated with Dopamine Grafts (2012) (127)
Neuroprotective and behavioral efficacy of nerve growth factor-transfected hippocampal progenitor cell transplants after experimental traumatic brain injury. (2001) (126)
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain (2009) (125)
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector (2002) (125)
Axonal degeneration and regeneration of bulbo-spinal indolamine neurons after 5,6-dihydroxytryptamine treatment. (1973) (123)
Intracephalic embryonic neural implants in the adult rat brain. I. Growth and mature organization of birainstem, cerebellar, and hippocampal implants (1983) (123)
Regional distribution of catecholamines in monkey cerebral cortex, evidence for a dopaminergic innervation of the primate prefrontal cortex (1978) (123)
Serotonin-dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias. (2008) (123)
Striatal c‐fos Induction by Cocaine or Apomorphine Occurs Preferentially in Output Neurons Projecting to the Substantia Nigra in the Rat (1992) (122)
Brain-derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts (1993) (122)
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release (1988) (121)
Restoration of rhythmic slow activity (θ) in the subcortically denervated hippocampus by fetal CNS transplants (1987) (121)
Trophic Factor Gene Therapy for Parkinson's Disease (2013) (119)
Intrinsic Organization and Connectivity of Intrastriatal Striatal Transplants in Rats as Revealed by DARPP‐32 Immunohistochemistry: Specificity of Connections with the Lesioned Host Brain (1989) (119)
Neural transplantation : a practical approach (1992) (118)
Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia (2006) (118)
Long-term functional recovery from age-induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain. (1996) (116)
Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration. (2008) (114)
Modeling CNS neurodegeneration by overexpression of disease-causing proteins using viral vectors (2003) (113)
The aluminum-formaldehyde (ALFA) histofluorescence method for improved visualization of catecholamines and indoleamines. 1. A detailed account of methodology for central nervous tissue using paraffin, cryostat or vibratome sections (1980) (113)
Fifty years of dopamine research (2007) (113)
Intranigral Transplants of GABA-Rich Striatal Tissue Induce Behavioral Recovery in the Rat Parkinson Model and Promote the Effects Obtained by Intrastriatal Dopaminergic Transplants (1999) (112)
Dopaminergic transplants in experimental parkinsonism: cellular mechanisms of graft-induced functional recovery (1992) (112)
Fetal mesencephalic neurons survive and extend long axons across peripheral nervous system grafts inserted into the adult rat striatum (1984) (111)
Simultaneous use of retrograde fluorescent tracers and fluorescence histochemistry for convenient and precise mapping of monoaminergic projections and collateral arrangements in the CNS (1979) (109)
The Importance of Graft Placement and Task Complexity for Transplant‐Induced Recovery of Simple and Complex Sensorimotor Deficits in Dopamine Denervated Rats (1990) (109)
Regional Specification of Neurosphere Cultures Derived from Subregions of the Embryonic Telencephalon (2002) (108)
Cell therapy in Parkinson’s disease (2004) (108)
Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cell suspensions implanted in different brain sites. (1983) (108)
Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease (2019) (107)
Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. I. Evidence for anatomical reconstruction of the nigrostriatal pathway (1995) (106)
Grafts of EGF‐responsive neural stem cells derived from GFAP‐hNGF transgenic mice: Trophic and tropic effects in a rodent model of Huntington's disease (1997) (105)
Mechanisms of regrowth in the bulbospinal serotonin system following 5,6-dihydroxytryptamine induced axotomy. II. Fluorescence histochemical observations (1980) (104)
Selective Immunolesioning of the Basal Forebrain Cholinergic System Disrupts Short‐term Memory in Rats (1996) (104)
Growth and Functional Efficacy of Intrastriatal Nigral Transplants Depend on the Extent of Nigrostriatal Degeneration (2001) (104)
Better cells for brain repair (1993) (103)
Comparison of growth and reinnervation properties of cholinergic neurons from different brain regions grafted to the hippocampus (1988) (103)
Dopaminergic transplants normalize amphetamine- and apomorphine-induced Fos expression in the 6-hydroxydopamine-lesioned striatum (1992) (103)
Development of intrastriatal striatal grafts and their afferent innervation from the host (1991) (101)
Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease. (2010) (100)
The Transcription Factor SREBP-1c Is Instrumental in the Development of β-Cell Dysfunction* (2003) (98)
In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133 (2007) (95)
Cholinergic reinnervation of the rat hippocampus by septal implants is stimulated by perforant path lesion (1979) (94)
Neurotoxic indoleamines and monoamine neurons. (1976) (94)
Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement. (2000) (93)
Axonal degeneration associated with a defective blood–brain barrier in cerebral implants (1975) (93)
Mechanisms of function of neural grafts in the adult mammalian brain. (1987) (92)
Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model (2009) (91)
Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra (2004) (91)
Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis—I. Biochemical and anatomical observations (1985) (91)
Cell Therapeutics in Parkinson’s Disease (2011) (91)
Cells of origin of the ventral cholinergic septohippocampal pathway undergoing compensatory collateral sprouting following fimbria-fornix transection (1984) (90)
Transection of Corticostriatal Afferents Reduces Amphetamine‐ and Apomorphine‐induced Striatal Fos Expression and Turning Behaviour in Unilaterally 6‐Hydroxydopamine‐lesioned Rats (1993) (88)
Overstimulation and beta-cell function. (2001) (88)
Grafted noradrenergic neurons suppress seizure development in kindling-induced epilepsy. (1987) (87)
Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors. (2005) (87)
Efferent Projections to the Host Brain from Intrastriatal Striatal Mouse‐to‐rat Grafts: Time Course and Tissue‐type Specificity as Revealed by a Mouse Specific Neuronal Marker (1991) (86)
Ex vivo nerve growth factor gene transfer to the basal forebrain in presymptomatic middle-aged rats prevents the development of cholinergic neuron atrophy and cognitive impairment during aging. (1998) (86)
Neuronal differentiation following transplantation of expanded mouse neurosphere cultures derived from different embryonic forebrain regions (2003) (85)
Classical transmitters and transmitter receptors in the CNS (1984) (85)
The prefrontal ‘cortex’ in the pigeon. Biochemical evidence (1985) (85)
Classical transmitters in the CNS (1984) (84)
Acetylcholine release from intrahippocampal septal grafts is under control of the host brain. (1990) (84)
Intracerebral grafting of neuronal cell suspensions. VII. Recovery of choline acetyltransferase activity and acetylcholine synthesis in the denervated hippocampus reinnervated by septal suspension implants. (1983) (84)
Intracerebral grafting of neuronal cell suspensions. VI. Survival and growth of intrahippocampal implants of septal cell suspensions. (1983) (84)
Cortical grafts prevent atrophy of cholinergic basal nucleus neurons induced by excitotoxic cortical damage (1986) (83)
Chemical lesioning of central monoamine axons by means of 5,6-dihydroxytryptamine and 5,7-dihydroxytryptamine. (1974) (83)
Effect of Prior Dopamine Denervation on Survival and Fiber Outgrowth from Intrastriatal Fetal Mesencephalic Grafts (1990) (82)
Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells. (1986) (82)
Stimulation of growth of new axonal sprouts from lesioned monoamine neurones in adult rat brain by nerve growth factor. (1973) (81)
Growth of intact central adrenergic axons in the denervated lateral geniculate body. (1972) (81)
Behaviour-dependent changes in acetylcholine release in normal and graft-reinnervated hippocampus: Evidence for host regulation of grafted cholinergic neurons (1992) (80)
Intracephalic implants: a technique for studying neuronal interactions. (1979) (80)
Transplanted septal neurons make viable cholinergic synapses with a host hippocampus (1985) (79)
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons (2015) (79)
The integration and function of striatal grafts. (2000) (78)
Characterization of gaba release from intrastriatal striatal transplants: Dependence on host-derived afferents (1993) (78)
Regeneration of central cholinergic neurones in the adult rat brain (1976) (77)
Fetal striatal neurons grafted into the ibotenate lesioned adult striatum: Efferent projections and synaptic contacts in the host globus pallidus (1990) (77)
Axon outgrowth from grafts of human embryonic spinal cord in the lesioned adult rat spinal cord. (1992) (77)
Effects of 5,6-dihydroxytryptamine on nerve terminal serotonin and serotonin uptake in the rat brain. (1973) (76)
MODE AND MECHANISM OF ACTION OF NEUROTOXIC INDOLEAMINES: A REVIEW AND A PROGRESS REPORT (1978) (76)
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry (2004) (76)
Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. II. Transplant-induced behavioral recovery (1995) (76)
Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia. (2010) (75)
In vivo acetylcholine release as measured by microdialysis is unaltered in the hippocampus of cognitively impaired aged rats with degenerative changes in the basal forebrain (1991) (75)
Neurobiology: Self-repair in the brain (2000) (75)
Integrated systems of the CNS (1987) (74)
Host Corticostriatal Fibres Establish Synaptic Connections with Grafted Striatal Neurons in the Ibotenic Acid Lesioned Striatum (1989) (74)
Consumption of whole grain reduces risk of deteriorating glucose tolerance, including progression to prediabetes. (2013) (73)
Role of serotonin neurons in the induction of levodopa‐ and graft‐induced dyskinesias in Parkinson's disease (2010) (73)
Loss of AChE- and NGFr-labeling precedes neuronal death of axotomized septal-diagonal band neurons: Reversal by intraventricular NGF infusion (1991) (73)
Intrahippocampal grafts of fetal basal forebrain tissue alter place fields in the hippocampus of rats with fimbria-fornix lesions (1989) (72)
Synaptic connections formed by grafts of different types of cholinergic neurons in the host hippocampus (1990) (72)
Effects of localized intracerebral injections of nerve growth factor on the regenerative growth of lesioned central noradrenergic neurones. (1974) (72)
Glucose-induced [Ca2+]i abnormalities in human pancreatic islets: important role of overstimulation. (2000) (72)
Intracerebral Grafting of Dopamine Neurons (1987) (71)
De- and regeneration of brain serotonin neurons following 5,7-dihydroxytryptamine treatment: Effects on serum LH, FSH and prolactin levels in male rats (1977) (71)
Histochemical demonstration of tryptamine. Properties of the formaldehyde-induced fluorophores of tryptamine and related indole compounds in models. (1968) (71)
Injury induced c‐Jun expression and phosphorylation in the dopaminergic nigral neurons of the rat: correlation with neuronal death and modulation by glial‐cell‐line‐derived neurotrophic factor (2001) (71)
Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis (2009) (71)
Adrenergic innervation of the human uterus (1979) (70)
Practical aspects of the use of human fetal brain tissue for intracerebral grafting. (1990) (70)
Dopamine-rich transplants in rats with 6-OHDA lesions of the ventral tegmental area. I. Effects on spontaneous and drug-induced locomotor activity (1984) (69)
ANALYSIS OF FLUORESCENCE EXCITATION PEAK RATIOS FOR THE CELLULAR IDENTIFICATION OF NORADRENALINE, DOPAMINE OR THEIR MIXTURES (1972) (69)
Prefrontal Corticostriatal Afferents Maintain Increased Enkephalin Gene Expression in the Dopamine‐denervated Rat Striatum (1994) (69)
Mechanisms of regrowth of the bulbospinal serotonin system following 5,6-dihydroxytryptamine induced axotomy. I. Biochemical correlates (1980) (69)
Alpha-Synuclein Produces Early Behavioral Alterations via Striatal Cholinergic Synaptic Dysfunction by Interacting With GluN2D N-Methyl-D-Aspartate Receptor Subunit (2016) (68)
EFFECTS OF NEONATAL LESIONS OF THE BASAL FOREBRAIN CHOLINERGIC SYSTEM BY 192 IMMUNOGLOBULIN G-SAPORIN: BIOCHEMICAL, BEHAVIOURAL AND MORPHOLOGICAL CHARACTERIZATION (1996) (68)
Involvement of the serotonin system in L-dopa-induced dyskinesias. (2008) (67)
Cell and tissue transplantation into the adult brain (1987) (67)
Intracerebral grafting of neuronal cell suspensions. VIII. Survival and growth of implants of nigral and septal cell suspensions in intact brains of aged rats. (1983) (67)
The primate nervous system (1997) (67)
Nigral transplants reinnervating the dopamine-depleted neostriatum can sustain intracranial self-stimulation. (1983) (67)
Spatial learning and memory following fimbria-fornix transection and grafting of fetal septal neurons to the hippocampus (2004) (67)
Cell replacement strategies for neurodegenerative disorders. (2000) (66)
Conditionally Immortalized Neural Progenitor Cells Grafted to the Striatum Exhibit Site-Specific Neuronal Differentiation and Establish Connections with the Host Globus Pallidus (1996) (66)
Cell suspension grafts of noradrenergic locus coeruleus neurons in rat hippocampus and spinal cord: Reinnervation and transmitter turnover (1986) (66)
Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons (2004) (65)
Survival of intracerebrally grafted rat dopamine neurons previously cultured in vitro (1985) (64)
Are Stem Cell-Based Therapies for Parkinson’s Disease Ready for the Clinic in 2016? (2016) (63)
Extensive migration and target innervation by striatal precursors after grafting into the neonatal striatum (1997) (63)
EGF Infusion Stimulates the Proliferation and Migration of Embryonic Progenitor Cells Transplanted in the Adult Rat Striatum (2000) (63)
Isolation and characterization of neural precursor cells from the Sox1–GFP reporter mouse (2005) (62)
Improved beta cell function after short-term treatment with diazoxide in obese subjects with type 2 diabetes. (2002) (62)
Grafts of fetal locus coeruleus neurons in rat amygdala-piriform cortex suppress seizure development in hippocampal kindling (1989) (62)
Functional reinnervation of the denervated neostriatum by nigral transplants (1980) (62)
The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting (1986) (61)
Cell Therapy for Parkinson's Disease: What Next? (2013) (61)
Hippocampal deafferentation: transplant‐derived reinnervation and functional recovery (1984) (60)
Regeneration of normal terminal innervation patterns by central noradrenergic neurons after 5,7-dihydroxytryptamine-induced axotomy in the adult rat (1979) (60)
Microspectrofluorimetric Characterization of Monoamines in the Central Nervous System: Evidence for a New Neuronal Monoamine-like Compound (1971) (59)
Decline in visual attention and spatial memory in aged rats (1999) (59)
The Meso-Telencephalic Dopamine Neuron System: A Review of Its Anatomy (1978) (59)
Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon (2006) (59)
Local regulation of compensatory noradrenergic hyperactivity in the partially denervated hippocampus (1983) (58)
Conditionally immortalized neural progenitor cell lines integrate and differentiate after grafting to the adult rat striatum. A combined autoradiographic and electron microscopic study (1996) (58)
Grafted septal neurons form cholinergic synaptic connections in the dentate gyrus of behaviorally impaired aged rats (1986) (57)
AN IMPROVEMENT OF THE HISTOCHEMICAL FLUOROSCENCE METHOD FOR MONOAMINES OBSERVATIONS ON VARYING EXTRACTABILITY OF FLUOROPHORES IN DIFFERENT NERVE FIBERS (1968) (57)
Ultrastructural evidence of synaptogenesis in the adult rat dentate gyrus from brain stem implants (1979) (57)
Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells (2015) (57)
Reformation of the Nigrostriatal Pathway by Fetal Dopaminergic Micrografts into the Substantia Nigra Is Critically Dependent on the Age of the Host (1999) (57)
Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host neostriatum (2004) (57)
Re-establishment of functional connections by regenerating central adrenergic and cholinergic axons (1975) (57)
Analysis of neuronal microcircuits and synaptic interactions (1990) (57)
Behavioral dependence of the electrical activity of intracerebrally transplanted fetal hippocampus (1987) (57)
Organization of mesencephalic dopamine neurons projecting to neocortex and septum. (1977) (57)
Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors (2015) (56)
Conditioned turning in rats: Dopaminergic involvement in the initiation of movement rather than the movement itself (1983) (56)
Inhibition of the regenerative growth of central noradrenergic neurons by intracerebrally administered anti-NGF serum. (1974) (55)
Cellular activity of intracerebrally transplanted fetal hippocampus during behavior (1987) (54)
Organization and ultrastructural identification of the catecholamine nerve terminals in the neural lobe and pars intermedia of the rat pituitary (2004) (54)
Extracellular γ-aminobutyric acid levels in the rat caudate-putamen: Monitoring the neuronal and glial contribution by intracerebral microdialysis (1993) (53)
Monoamines in the pituitary gland of the pig. (1967) (53)
Testosterone intake and aggressiveness: Real effect or anticipation? (1994) (53)
Functional activity of intrahippocampal septal grafts is regulated by catecholaminergic host afferents as studied by microdialysis of acetylcholine (1993) (52)
GDNF is not required for catecholaminergic neuron survival in vivo (2015) (52)
Dopamine-rich transplants in experimental parkinsonism (1983) (52)
Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons (2015) (52)
Intracerebral xenografts of dopamine neurons: the role of immunosuppression and the blood-brain barrier (2004) (51)
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease (2019) (50)
Ex Vivo Gene Transfer of Brain‐derived Neurotrophic Factor to the Intact Rat Forebrain: Neurotrophic Effects on Cholinergic Neurons (1996) (50)
Methods in chemical neuroanatomy (1983) (50)
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors (2010) (50)
Basic neural transplantation techniques. I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain. (1997) (50)
The Amphetamine Induced Rotation Test: A Re-Assessment of Its Use as a Tool to Monitor Motor Impairment and Functional Recovery in Rodent Models of Parkinson’s Disease (2019) (49)
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease (2014) (49)
mTOR inhibition alleviates L-DOPA-induced dyskinesia in parkinsonian rats. (2013) (49)
On the possible existence of a new intraneuronal monoamine in the spinal cord of the rat. (1970) (49)
Parkinson disease gene therapy moves toward the clinic (2000) (48)
Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats (2004) (48)
NEW ASPECTS ON REACTION MECHANISMS IN THE FORMALDEHYDE HISTOFLUORESCENCE METHOD FOR MONOAMINES (1973) (48)
Further studies on the use of the fluorescent retrograde tracer True Blue in combination with monoamine histochemistry (1985) (48)
Neural transplantation in Parkinson's disease: the Swedish experience. (1990) (48)
Survival of expanded dopaminergic precursors is critical for clinical trials (1998) (48)
Reformation in adult rats of functional septo-hippocampal connections by septal neurons regenerating across an embryonic hippocampal tissue bridge (1981) (48)
Morphological plasticity of central adrenergic neurons. (1973) (47)
Reformation of the severed septohippocampal cholinergic pathway in the adult rat by transplanted septal neurons (1977) (46)
Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia (2013) (46)
Preservation of fetal ventral mesencephalic cells by cool storage: in-vitro viability and TH-positive neuron survival after microtransplantation to the striatum (1995) (46)
FLUORESCENCE HISTOCHEMISTRY OF BIOGENIC MONOAMINES A STUDY OF THE CAPACITY OF VARIOUS CARBONYL COMPOUNDS TO FORM FLUOROPHORES WITH BIOGENIC MONOAMINES IN GAS PHASE REACTIONS (1972) (46)
ACID CATALYSIS OF THE FORMALDEHYDE CONDENSATION REACTION FOR SENSITIVE HISTOCHEMICAL DEMONSTRATION OF TRYPTAMINES AND 3-METHOXYLATED PHENYLETHYLAMINES (1970) (45)
Monoamines in the hypothalamo-hypophyseal system of the mouse with special reference to the ontogenetic aspects (2004) (45)
Neurturin enhances the survival of intrastriatal fetal dopaminergic transplants. (1999) (45)
Brain-derived neurotrophic factor enhances striatal neuropeptide expression in both the intact and the dopamine-depleted rat striatum. (1994) (45)
GDNF and Parkinson’s Disease: Where Next? A Summary from a Recent Workshop (2020) (45)
BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats (2017) (44)
Differentiation of the RN33B Cell Line into Forebrain Projection Neurons after Transplantation into the Neonatal Rat Brain (2002) (44)
Histochemical characterization of a tryptamine-like substance stored in cells of the mammalian adenohypophysis. (1969) (44)
B-cell insensitivity in vitro: reversal by diazoxide entails more than one event in stimulus-secretion coupling. (1993) (43)
Neural grafting in the aged rat brain. (1986) (43)
Cell therapy for Parkinson's disease: problems and prospects. (2005) (43)
Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats (2018) (43)
Mechanisms of fluorophore formation in the histochemical glyoxylic acid method for monoamines (2004) (43)
Regeneration and plasticity of central serotoninergic neurons: a review. (1981) (43)
Prefrontal cortex: dense dopaminergic input in the newborn rat. (1982) (43)
The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study (2015) (42)
Ontogeny of transmitters and peptides in the CNS (1992) (42)
Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets. (1999) (42)
Transplantation strategies in the treatment of Parkinson's disease: experimental basis and clinical trials (1989) (41)
Transplanted dopaminergic neurons: More or less? (2001) (41)
Long-term recovery of serotonin concentrations in the rat CNS following 5,6-dihydroxytryptamine. (1973) (41)
Phenotypic and molecular identity of cells in the adult subventricular zone in vivo and after expansion in vitro (2003) (41)
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation. (2010) (41)
Microspectrofluorimetric and chemical investigation of catecholamine-containing structures in the thoracic ganglia of trichoptera. (1970) (40)
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease (2012) (40)
Neural Tissue Transplantation Research (1983) (40)
Differential regulation of neuropeptide mRNA expression in intrastriatal striatal transplants by host dopaminergic afferents. (1992) (40)
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression (2015) (39)
Neurotoxicity of hydroxylated tryptamines: structure-activity relationships. 2. In vitro studies on monoamine uptake inhibition and uptake impairment. (1975) (39)
Organization of the Dopamine and Noradrenaline Innervations of the Median Eminence-Pituitary Region in the Rat (1974) (39)
Chapter 3 – Chemical Lesioning of Indoleamine Pathways1 (1977) (39)
Gene Therapy for Dopamine Replacement in Parkinson´s Disease (2009) (39)
Dysfunctional insulin secretion in type 2 diabetes: role of metabolic abnormalities (2000) (39)
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease (2018) (38)
Peripheral sympathetic innervation and serotonin cells in the habenular region of the rat brain (2004) (38)
Rat fetal brain tissue grafts survive and innervate host brain following five day pregraft tissue storage (1985) (37)
Intracerebral grafting of neuronal cell suspensions. IV. Behavioural recovery in rats with unilateral implants of nigral cell suspensions in different forebrain sites (1983) (37)
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor (2005) (37)
Monoamine-containing fibres in the pituitary neuro-intermediate lobe of the pig and rat (2004) (37)
TFEB: Pathogenic role and therapeutic target in Parkinson disease. (2013) (36)
The Functional Impact of the Intrastriatal Dopamine Neuron Grafts in Parkinsonian Rats Is Reduced with Advancing Disease (2007) (36)
Neural Grafting in Animal Models of Neurodegenerative Diseases (1985) (36)
Reconstruction of brain circuitries by neural transplants (1979) (36)
Transplantation Strategies in Spinal Cord Regeneration (1984) (36)
Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts (2005) (36)
Identification of dopamine and noradrenaline in nervous structures of the insect brain. (1971) (36)
Brain-derived neurotrophic factor and neurotrophin- 4 5 modify neurotransmitter-related gene expression in the 6-hydroxydopamine-lesioned rat striatum (1995) (35)
Intracerebral grafting of neuronal cell suspensions into the adult brain. (1984) (35)
Generation and Transplantation of EGF-Responsive Neural Stem Cells Derived from GFAP–hNGF Transgenic Mice (1997) (35)
Hippocampal deafferentation: transplantderived reinnervation and functional recovery (1982) (35)
Replacing Dopamine Neurons in Parkinson’s Disease: How did it happen? (2017) (35)
Intracerebral grafting of embryonic neural cells into the adult host brain: an overview of the cell suspension method and its application. (1983) (35)
Cell replacement therapy: Helping the brain to repair itself (2004) (34)
ACID CATALYSIS OF THE FORMALDEHYDE CONDENSATION REACTION FOR A SENSITIVE HISTOCHEMICAL DEMONSTRATION OF TRYPTAMINES AND 3-METHOXYLATED PHENYLETHYLAMINES 2. CHARACTERIZATION OF AMINE FLUOROPHORES AND APPLICATION TO TISSUES (1971) (34)
Neurotransmitter-related gene expression in intrastriatal striatal transplants—I. Phenotypical characterization of striatal and non-striatal graft regions (1995) (33)
Seizure Development and Noradrenaline Release in Kindling Epilepsy after Noradrenergic Reinnervation of the Subcortically Deafferented Hippocampus by Superior Cervical Ganglion or Fetal Locus Coeruleus Grafts (1994) (33)
Amelioration of spatial navigation and short‐term memory deficits by grafts of foetal basal forebrain tissue placed into the hippocampus and cortex of rats with selective cholinergic lesions (1998) (33)
Evidence for the existence of serotonin-, dopamine-, and noradrenaline-containing neurons in the gut of Lampetra fluviatilis (1973) (32)
Dopaminergic transplants in experimental parkinsonism: Cellular mechanisms of graft induced functional recovery (1992) (32)
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum—II. Cortical afferents (1989) (32)
Reinnervation of the denervated adult spinal cord of rats by intraspinal transplants of embryonic brain stem neurons (2004) (32)
Extensive efferent projections of intra-striatally transplanted striatal neurons as revealed by a species-specific neurofilament marker and anterograde axonal tracing. (1990) (31)
Neurotoxicity of hydroxylated tryptamines: structure-activity relationships. 1. Long-term effects on monoamine content and fluorescence morphology of central monoamine neurons. (1975) (31)
Fetal cortical cell suspension grafts to the excitotoxically lesioned neocortex: anatomical and neurochemical studies of trophic interactions. (1988) (31)
Dissecting Embryonic Neural Tissues for Transplantation (2000) (31)
Stem cells: Breaking the brain-blood barrier (1999) (31)
The serotonergic system in L-DOPA-induced dyskinesia: pre-clinical evidence and clinical perspective (2018) (31)
Fos expression in intrastriatal striatal grafts: regulation by host dopaminergic afferents (1992) (30)
Compensatory changes of in vivo acetylcholine and noradrenaline release in the hippocampus after partial deafferentation, as monitored by microdialysis (1993) (30)
Evaluation of the regenerative capacity of central dopaminergic, noradrenergic and cholinergic neurones using iris implants as targets (1977) (30)
Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment. (2004) (29)
Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation. (2012) (29)
Experimental studies on the induction and prevention of retrograde degeneration of basal forebrain cholinergic neurons. (1986) (29)
Host regulation of glial markers in intrastriatal grafts of conditionally immortalized neural stem cell lines (1996) (29)
Transection of corticostriatal afferents abolishes the hyperexpression of Fos and counteracts the development of rotational overcompensation induced by intrastriatal dopamine-rich grafts when challenged with amphetamine (1994) (29)
HAS NERVE GROWTH FACTOR A ROLE IN THE REGENERATION OF CENTRAL AND PERIPHERAL CATECHOLAMINE NEURONS (1974) (28)
Contributions of different afferent pathways to the catecholamine and 5-hydroxytryptamine-innervation of the amygdala: A neurochemical and histochemical study (1979) (28)
Overstimulation and β-cell function (2001) (27)
Effects of Diazoxide on Gene Expression in Rat Pancreatic Islets Are Largely Linked to Elevated Glucose and Potentially Serve to Enhance β-Cell Sensitivity (2007) (27)
Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain (2008) (27)
Hyperoxia inhibits glucose-induced insulin secretion and mitochondrial metabolism in rat pancreatic islets. (2014) (27)
Electrical stimulation of the lateral habenula increases hippocampal noradrenaline release as monitored by in vivo microdialysis (2004) (27)
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD (2020) (27)
Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: a quantitative radioautographic study of [3H]dopamine uptake (1989) (26)
First step towards cell therapy for Huntington's disease (2000) (26)
Transmitter release from transplants of fetal ventral mesencephalon or locus coeruleus in the rat frontal cortex and nucleus accumbens: effects of pharmacological and behaviorally activating stimuli (1994) (26)
Structural and functional analysis of raphe neurone implants into denervated rat spinal cord (1989) (26)
Neuronal replacement by intracerebral neural implants in animal models of neurodegenerative disease. (1988) (26)
Can human fetal dopamine neuron grafts provide a therapy for Parkinson's disease? (1988) (25)
Amphetamine-induced rotation and l-DOPA-induced dyskinesia in the rat 6-OHDA model: A correlation study (2012) (25)
Preconditioning with Associated Blocking of Ca2+ Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells (2013) (25)
Cytofluorometry of Biogenic Monoamines in the Falck-Hillarp Method. Structural Identification by Spectral Analysis (1973) (25)
Extensive reinnervation of the hippocampus by embryonic basal forebrain cholinergic neurons grafted into the septum of neonatal rats with selective cholinergic lesions (1996) (25)
An improved histofluorescence procedure for freeze-dried paraffin-embedded tissue based on combined formaldehyde-glyoxylic acid perfusion with high magnesium content and acid pH (1976) (25)
INTRACEREBRAL GRAFTING OF DISSOCIATED CNS TISSUE SUSPENSIONS (1983) (25)
Retrograde degenerative changes in the substantia nigra pars compacta following an excitotoxic lesion of the striatum (1994) (25)
REGENERATION OF SEROTONIN NEURONS IN THE RAT BRAIN AFTER 5,6‐DIHYDROXYTRYPTAMINE‐INDUCED AXOTOMY * (1978) (25)
Immunological aspects of neural grafting in the mammalian central nervous system. (1988) (25)
Grafts of fetal cholinergic neurons to the deafferented hippocampus. (1987) (24)
Fluorophore formation from catecholamines and related compounds in the glyoxylic acid fluorescence histochemical method (1974) (24)
Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion (2004) (24)
Standardization and evaluation of a sensitive and convenient assay for melanocyte-stimulating hormone using Anolis skin in vitro. (1972) (23)
DEGENERATIVE EFFECTS OF VARIOUS NEUROTOXIC INDOLEAMINES ON CENTRAL MONOAMINE NEURONS * (1978) (23)
Striatal grafts in the ibotenic acid-lesioned neostriatum: functional studies. (1988) (23)
Adrenergic innervation of the human uterus. Disappearance of the transmitter and transmitter-forming enzymes during pregnancy. (1979) (23)
Morphological and functional studies on the serotoninergic innervation of the inferior olive. (1981) (22)
Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells (2010) (22)
Striatal Neuron Differentiation from Neurosphere-Expanded Progenitors Depends on Gsh2 Expression (2004) (22)
Bronchial reactivity, smoking, and alpha1-antitrypsin. A population-based study of middle-aged men. (1982) (22)
Application of the glyoxylic acid method to Vibratome sections for the improved visualization of central catecholamine neurons (2004) (22)
Microspectrofluorometric characterization of catecholamines and indolamines on silica gel thin layer after formaldehyde condensation. (1970) (22)
Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson’s disease (2015) (22)
Improved catecholamine histofluorescence in the developing brain based on the magnesium and aluminum (ALFA) perfusion techniques: Methodology and anatomical observations (1982) (21)
Formation of synaptic graft-host connections by noradrenergic locus coeruleus neurons transplanted into the adult rat hippocampus (1990) (21)
Transplantation techniques for the study of regeneration in the central nervous system. (1978) (21)
Neurotransmitter-related gene expression in intrastriatal striatal transplants—II. Characterization of efferent projecting graft neurons (1995) (21)
Studies on the fluorophore forming reactions of various catecholamines and tetrahydroisoquinolines with glyoxylic acid. (1975) (21)
De- and regeneration of the bulbospinal serotonin neurons in the rat following 5,6-or 5,7-Dihydroxytryptamine treatment (2004) (21)
Pituitary monoamines of the cat with special reference to the presence of an unidentified monoamine-like substance in the adenohypophysis (1968) (21)
The production of catecholamine-containing cells in vitro by young chick embryos: effects of "nerve growth factor" (NGF) and its antiserum. (1973) (21)
Beneficial effects of K‐ATP channel openers in diabetes: an update on mechanisms and clinical experiences (2009) (20)
AN ENZYMIC BARRIER MECHANISM FOR MONOAMINE PRECURSORS IN THE NEWLY‐FORMING BRAIN CAPILLARIES FOLLOWING ELECTROLYTIC OR MECHANICAL LESIONS (1969) (20)
Region-specific migration of embryonic glia grafted to the neonatal brain (1998) (20)
Openers of ATP-dependent K+-channels protect against a signal-transduction-linked and not freely reversible defect of insulin secretion in a rat islet transplantation model of Type 2 diabetes (2004) (20)
Diabetes reduces β-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction (2012) (20)
Impact of metabolic abnormalities for beta cell function: Clinical significance and underlying mechanisms (2009) (20)
Behavioral functions of dopamine neurons (2009) (20)
Further evidence for the possible coexistence of 5-hydroxytryptamine and substance P in medullary raphe neurones of rat brain [proceedings]. (1979) (20)
A possibility for differentiating dopamine from noradrenaline in tissue sections by microspectrofluorometry. (1968) (20)
Investigating optimal β‐cell‐preserving treatment in latent autoimmune diabetes in adults: Results from a 21‐month randomized trial (2019) (20)
371 – NEUROTOXICITY OF HYDROXYLATED TRYPTAMINES: STRUCTURE-ACTIVITY RELATIONSHIP (1977) (20)
The intracerebrally cultured ‘microbrain’: A new tool in developmental neurobiology (1978) (19)
FLUORESCENCE HISTOCHEMICAL DEMONSTRATION OF PEPTIDES WITH NH2- OR COOH-TERMINAL TRYPTOPHAN OR DOPA BY CONDENSATION WITH GLYOXYLIC ACID (1973) (19)
Intracerebral microdialysis as a tool to monitor transmitter release from grafted cholinergic and monoaminergic neurons (1990) (19)
Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model (2003) (19)
Anatomical and functional consequences of grafting mesencephalic neurons into a peripheral nerve “bridge” connected to the denervated striatum (2004) (19)
Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system (1988) (19)
Animal models for preclinical Parkinson's research: An update and critical appraisal. (2020) (19)
Neuroanatomy of Central Dopamine Pathways: Review of Recent Progress (1982) (19)
Intracerebral grafting of inhibitory neurons. A new strategy for seizure suppression in the central nervous system. (1992) (19)
Comparison of formaldehyde gas and Procházka reagents for the detection of biogenic monoamines by thin-layer chromatography. (1970) (19)
TFEB (2013) (19)
Chemical degeneration of indolamine axons in rat brain by 5,6-dihydroxytryptamine (1972) (19)
Trophic and growth-regulating mechanisms in the central nervous system monitored by intracerebral neural transplants. (1987) (18)
Catecholaminergic Brain Stem Regulatory Systems (2011) (18)
Neurobiology. Better cells for brain repair. (1993) (18)
Animal Models of Parkinson's Disease: Are They Useful or Not? (2020) (18)
Host Brain Regulation of Fetal Locus Coeruleus Neurons Grafted to the Hippocampus in 6‐Hydroxydopamine‐Treated Rats. An Intracerebral Microdialysis Study (1991) (18)
The aluminum-formaldehyde (ALFA) histofluorescence method for improved visualization of catecholamines and indoleamines. 2. Model experiments (1980) (18)
CNS transplantation: structural and functional recovery from brain damage. (1982) (18)
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation (2014) (17)
Cell replacement therapy: Helping the brain to repair itself (2004) (17)
Toll-Like Receptor 3 Influences Glucose Homeostasis and β-Cell Insulin Secretion (2015) (17)
Evidence that insulin secretion influences SNAP-25 through proteasomal activation. (2005) (17)
The Peripheral nervous system (1988) (17)
Intracerebral grafting of fetal noradrenergic locus coeruleus neurons: evidence for seizure suppression in the kindling model of epilepsy. (1988) (17)
Identification of the para-isomer of tyramine in rat brain. (1973) (17)
Striatal Neural Transplants in the Ibotenic Acid‐lesioned Rat Neostriatum (1987) (17)
Striatal grafts in the ibotenic acid-lesioned neostriatum: ultrastructural and immunocytochemical studies. (1988) (17)
Possible regeneration of γ-aminobutyric acid-containing fibres into irides transplanted into the central nervous system (1976) (17)
Monoamines in the bird median eminence (1968) (16)
Characterization of in Vivo Noradrenaline Release from Superior Cervical Ganglia or Fetal Locus Coeruleus Transplanted to the Subcortically Deafferented Hippocampus in the Rat (1993) (16)
Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft (2004) (16)
Cysteinyl dopa in human malignant melanoma. (1972) (16)
Reafferentation of the subcortically denervated hippocampus as a model for transplant-induced functional recovery in the CNS. (1990) (16)
A mathematical model of the mitochondrial NADH shuttles and anaplerosis in the pancreatic beta-cell. (2007) (15)
Survival and immunogenicity of dissociated allogeneic fetal neural dopamine-rich grafts when implanted into the brains of adult mice (2004) (15)
Septal transplant reinnervation of the hippocampus: Cholinergic enhancement of radial maze performance (1981) (15)
Functional Activity of Raphe Neurons Transplanted to the Hippocampus and Caudate‐Putamen (1987) (15)
Mitochondrial Respiration in Insulin-Producing β-Cells: General Characteristics and Adaptive Effects of Hypoxia (2015) (15)
Neuropeptide receptors in the CNS (1992) (15)
Behavioural effects of genetically engineered cells releasing dopa and dopamine after intracerebral grafting in a rat model of Parkinson's disease. (1991) (15)
Human fetal basal forebrain neurons grafted to the denervated rat hippocampus produce an organotypic cholinergic reinnervation pattern (1988) (15)
Regenerative properties of central monoamine neurons: studies in the adult rat using cerebral iris implants as targets. (1975) (15)
The use of neurotoxic dihydroxytryptamines as tools for morphological studies and localized lesioning of central indolamine neurons (1973) (14)
Gene transfer to the mammalian brain using neural stem cells: a focus on trophic factors, neuroregeneration, and cholinergic neuron systems. (1995) (14)
Intraneuronal indolamines in the central nervous system. (1976) (14)
A question of making it work (1994) (14)
Letters to the editor: New principles for microspectrofluorometric differentiation between DOPA, dopamine and noradrenaline. (1975) (14)
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter (2016) (14)
Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective (2020) (14)
Acetylcholine revisited (1995) (14)
Transplanted allogeneic fetal dopamine neurons survive and improve motor function in idiopathic Parkinson's disease. (1991) (13)
Neurotransmitter-related gene expression in intrastriatal striatal transplants. III. Regulation by host cortical and dopaminergic afferents. (1995) (13)
The arrangement of neurosecretory and catecholamine fibres in relation to the pituitary intermedia cells of the skate, Raja radiata (2004) (13)
Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry (2004) (13)
Generation of transplantable striatal projection neurons from human ESCs. (2012) (13)
Transplant-Induced Recovery from Brain Lesions: A Review of the Nigrostriatal Model (1983) (13)
Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area (2016) (13)
Replacing Dopamine Neurons in Parkinson's Disease: How did it happen? (2017) (13)
Restoration and deterioration of function by brain grafts in the septohippocampal system. (1988) (13)
Functional neural transplantation II. novel cell therapies for CNS disorders (2000) (12)
Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism. (1993) (12)
Role of Transient Receptor Potential Melastatin–like Subtype 5 Channel in Insulin Secretion From Rat &bgr;-Cells (2014) (12)
Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results. (2005) (12)
Neuropeptides in the CNS (1990) (12)
Recovery of brain noradrenaline after 5,7-dihydroxytryptamine-induced axonal lesions in the rat (1975) (12)
Grafts of Fetal Septal Cholinergic Neurons to the Hippocampal Formation in Aged or Fimbria‐Fornix‐lesioned Rats a (1987) (12)
Microspectrofluorometric identification of noradrenaline and 5-hydroxytryptamine on silica gel thin-layers (1968) (12)
Mechanisms and use of neural transplants for brain repair. (2017) (12)
Trophic effects on cholinergic striatal interneurons by submaxillary gland transplants. (1988) (11)
Extensive sympathetic denervation of the uterus during pregnancy as evidenced by tyrosine hydroxylase determinations in the guinea pig. (1980) (11)
Acetylcholine release from intrahippocampal septal grafts is under control by the host brain: a microdialysis study. (1990) (11)
Mickael Decressac in Nigral Dopamine Neurons Induced Down-Regulation of Nurr 1 Disrupts GDNF Signaling −-Synuclein (2012) (11)
Subcortical afferents to the prefrontal cortex: organization of mesencephalic dopaminergic and mediodorsal thalamic projections. (1977) (11)
Studies on host afferent inputs to fetal striatal transplants in the excitotoxically lesioned striatum. (1988) (11)
Glutamic acid decarboxylase gene expression in the dopamine-denervated striatum: effects of intrastriatal fetal nigral transplants or chronic apomorphine treatment. (1997) (10)
Functional recovery following brain damage: conceptual frameworks and biological mechanisms. (1982) (10)
Intracerebral Transplantation of Dopamine Neurons: Understanding the Functional Role of the Mesolimbocortical Dopamine System and Developing a Therapy for Parkinson's Disease a (1988) (10)
Transplantation of irides or sensory ganglia to the anterior eye chamber of the rat: Survival and sprouting of substance P-containing neurones (1982) (10)
Calcium Signaling in a Genetically Engineered Human Pancreatic &bgr;-Cell Line (2015) (10)
Application of the aluminum-formaldehyde (ALFA) histofluorescence method for demonstration of peripheral stores of catecholamines and indolamines in freeze-dried paraffin-embedded tissue, cryostat sections and whole-mounts (2004) (9)
Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson’s disease (2019) (9)
CONVERGING PROJECTIONS FROM MEDIODORSAL THALAMIC NUCLEUS AND MESENCEPHALIC DOPAMINERGIC-NEURONS TO NEOCORTEX IN 3 SPECIES (1975) (9)
Fluorescence histochemical demonstration of dopa thioethers by condensation with gaseous formaldehyde (1977) (9)
Use of CNS Implants to Promote Regeneration of Central Axons across Denervating Lesions in the Adult Rat Brain (1984) (9)
Use of Conditionally Immortalized Neural Progenitors for Transplantation and Gene Transfer to the CNS (1997) (9)
Transgenic reporter mice as tools for studies of transplantability and connectivity of dopamine neuron precursors in fetal tissue grafts. (2009) (9)
Parkinson's disease: Viral vector delivery of parkin generates model results in rats (2005) (8)
From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells. (2020) (8)
A TRPM4 Inhibitor 9-Phenanthrol Inhibits Glucose- and Glucagon-Like Peptide 1-Induced Insulin Secretion from Rat Islets of Langerhans (2017) (8)
Gli 1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells (2011) (8)
Evidence for Presence and Functional Effects of Kv1.1 Channels in β-Cells: General Survey and Results from mceph/mceph Mice (2011) (8)
Glyoxylic acid condensation: A new fluorescence histochemical method for sensitive and detailed tracing of central catecholamine neurons (1974) (8)
Intracerebral grafting of neuronal cell suspensions. VIII. Cell survival and axonal outgrcwth of dcpaminergic and cholinergic cells in the aged brain. (1983) (8)
BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia. (2020) (8)
Denervation‐induced Enhancement of Graft Survival and Growth (1987) (8)
Physiology of graft-host interactions in the rat hippocampus. (1988) (8)
Recent progress in aldehyde fluorescence histochemistry (1982) (8)
Intracerebral transplantation: prospects for neuronal replacement in neurodegenerative diseases. (1993) (8)
Recent Advances in Parkinson’s disease - translational and clinical research. (2010) (7)
A stimulatory effect by nerve growth factor on the regrowth of adrenergic nerve fibres in the mouse peripheral tissues after chemical sympathectomy with 6-hydroxydopamine (1973) (7)
Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair (2021) (7)
Synaptogenesis of Grafted Cholinergic Neurons (1987) (7)
Type 2 Diabetes—Effect of Compensatory Oversecretion as a Reason for β-Cell Collapse (2002) (7)
Compensation of Lesion-Induced Changes in Cerebral Metabolism and Behaviour by Striatal Neural Implants in a Rat Model of Huntington’s Disease (1985) (7)
Development of dopamine sensitive adenylate cyclase in hippocampus reinnervated by transplanted dopamine neurons: evidence for new functional contacts. (1977) (7)
Noradrenaline-containing transplants in the adult spinal cord of mammals. (1988) (7)
Synaptic connections of grafted dopaminergic neurons that reinnervate the neostriatum: A tyrosine hydroxylase immunohistochemical study (1985) (7)
Hypothalamus, hippocampus, amygdala, retina (1987) (7)
Transplanted precursors of nerve cells: Das and Altman and the revival of neural transplantation research (1999) (6)
Strain differences in catecholamine content of pigeon brains (1988) (6)
In utero gene transfer reveals survival effects of nerve growth factor on rat brain cholinergic neurones during development (1998) (6)
Transplantation of Dopamine Neurons: Extent and Mechanisms of Functional Recovery in Rodent Models of Parkinson's Disease (2009) (6)
Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates (2017) (6)
In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway (2008) (6)
Conditions for Neuronal Survival and Growth as Assessed by the Intracerebral Transplantation Technique in Lesion Models of the Adult CNS (1987) (6)
Fatty acids and beta-cell function (1997) (6)
Functional reactivation of the deafferented hippocampus by embryonic septal grafts as assessed by measurements of local glucose utilization (2004) (6)
Intracerebral Neuronal Grafting in Experimental Animal Models of Age‐related Motor Dysfunction a (1988) (6)
Fluorescence Microscopy of Biogenic Monoamines (1981) (6)
Grafts of fetal septal cholinergic neurons to the hippocampal formation in aged or fimbria-fornix lesioned rats. (1987) (6)
Transplantation of basal forebrain cholinergic neurons in the aged rat brain. (1986) (6)
In reply: fetal brain grafts and Parkinson's disease. (1990) (6)
The use of magnesium ions for sensitive visualization of catecholamines and serotonin in the CNS. (1977) (6)
Axonal regeneration of peripheral adrenergic neurons: Effects of antiserum to nerve growth factor in mouse (1974) (6)
Long distance axonal growth in the adult central nervous system (1994) (5)
Relief from glucose-induced over-stimulation sensitizes the adenylate cyclase-cAMP system of rat pancreatic islets. (2000) (5)
Cerebellum, basal ganglia, olfactory system (1996) (5)
Chapter 9 Coexistence during ontogeny and transplantation (1986) (5)
NGF IN MAINTENANCE AND REGENERATION OF ADRENERGIC AXONS (1976) (5)
Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system (2004) (5)
Brain Transplants: Can They Restore Single Unit Activity in the Hippocampus? (1985) (5)
Cell therapy in Parkinson’s disease (2004) (5)
Basal Forebrain Grafts in the Hippocampus and Neocortex: Regulation of Acetylcholine Release a (1993) (5)
Hormonal effects on development of transplanted embryonic hypothalamus (1980) (5)
In vivo microdialysis: a new approach for the study of functional activity of grafted monoaminergic neurons and their interaction with the host brain. (1990) (5)
Fruit and vegetable intake and risk of prediabetes and type 2 diabetes: results from a 20-year long prospective cohort study in Swedish men and women (2022) (5)
Glyoxylic acid spray reagent for thin-layer chromatographic identification of phenylethylamines and indolylethylamines. (1975) (5)
Transplantation in Huntington’s Disease: Experimental Basis and Clinical Perspectives (1993) (4)
Electrophysiological and pharmacological properties of neurons within solid basal forebrain transplants in the rat brain (1988) (4)
Aspects on the functional anatomy of the central catecholamine systems. (1977) (4)
CHOLECYSTOKININ CONTENT IN THE BASAL GANGLIA IN HUNTINGTONS-DISEASE - THE EXPRESSION OF CHOLECYSTOKININ IMMUNOREACTIVITY IN STRIATAL GRAFTS TO IBOTENIC ACID-LESIONED RAT STRIATUM (1985) (4)
Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder (2022) (4)
Third International Congress of Histochemistry and Cytochemistry (1968) (4)
Magnesium ions in catecholamine fluorescence histochemistry (1977) (4)
Interactive report Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF (2000) (4)
Gene Therapy for Parkinson's Disease Shows Promise (2011) (4)
Restoration of RSA (theta) in the Denervated Hippocampus by Brain Transplants (1986) (4)
In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy? (2021) (4)
Defective insulin secretion in the GK rat is not linked to excessive B-cell stimulation. (1997) (4)
Basic Transplantation Methods in Rodent Brain (2000) (4)
Catecholamines and DOPAC in cortical and neostriatal regions during rats' learning of delayed alternation. (1992) (4)
Neural Transplants and Recovery of Function after Brain Damage (1987) (4)
Fetal Dopamine Neurons Implanted Unilaterally into the Nucleus Accumbens Drive Amphetamine‐induced Locomotion and Circling (1987) (4)
Neuronal Replacement After Traumatic or Age-Dependent Brain Damage (1985) (4)
Failure of neonatally administered reserpine to affect the hypothalamic catecholamines in the adult rat. (1969) (4)
Restoration of cholinergic circuitry in the hippocampus by foetal grafts. (1989) (4)
Transsynaptic tracing and its emerging use to assess graft‐reconstructed neural circuits (2020) (4)
Release of acetylcholine and its dopaminergic control in slices from striatal grafts in the ibotenic acid-lesioned rat striatum (1988) (4)
A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System (2022) (3)
Regenerative sprouting of central monoamine neurons. (1973) (3)
Coexistence during ontogeny and transplantation. (1986) (3)
Uses of Neuronal Transplantation in Models of Neurodegenerative Diseases (1986) (3)
Combined formaldehyde and glyoxylic acid reactions (1975) (3)
Intracerebral neural grafting in animal models of aging brain: strategies, rationale and preliminary results. (1985) (3)
Functional neural transplantation III. Primary and stem cell therapies for brain repair, part I. Introduction. (2012) (3)
Parkinson’s disease laterality: a 11C-PE2I PET imaging study (2020) (3)
Spinal cord repair. A question of making it work. (1994) (3)
Aphagia and Adipsia after Serial Bilateral-6-OHDA Lesions: A Reply to G. L. Willis and G. C. Smith (1984) (3)
Cholecystokinin Content in the Basal Ganglia in Huntington's Disease (1985) (3)
Recent advances in Parkinson's disease: basic research. Preface. (2010) (3)
[Transplanted nerve cells survive and are functional for many years]. (1999) (3)
STRUCTURAL IDENTIFICATION BY SPECTRAL ANALYSIS (1973) (3)
Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism. (2012) (3)
Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells. (2019) (3)
Culture at low glucose up-regulates mitochondrial function in pancreatic β cells with accompanying effects on viability (2016) (3)
In Vivo Protection of Nigral Dopamine Neurons by Lentiviral Gene Transfer of the Novel GDNF-Family Member Neublastin/Artemin Volume 15, Number 2 (2000), pages 199–214 (2001) (2)
[Diabetes half-way between type 1 and type 2. LADA--the second biggest diabetic group where best treatment is uncertain]. (2008) (2)
[Cell transplantation and gene therapy in Parkinson disease]. (1996) (2)
Cognitive function. Acetylcholine revisited. (1995) (2)
Disease, transplantation and regeneration editorial overview (1991) (2)
Differentiation of embryonic hypothalamic transplants cultured on the choroidal pia in brains of adult rats (2004) (2)
Stem Derived Dopamine Neurons: Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease? (2021) (2)
Re-Establishment of Terminal Patterns in the Adult Rat Hippocampus by Grafted Monoaminergic Neurons (1978) (2)
Introduction (Part II). (2012) (2)
Time-dependent effects on circulating cytokines in patients with LADA: A decrease in IL1-ra and IL-1 beta is associated with progressive disease. (2022) (2)
Histochemical demonstration of monoamine neuron systems in the human fetal brain (1974) (2)
Cell Stem Cell Clinical Progress Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson ’ s Disease (2014) (2)
Search for biochemical changes following presumed increase of neural activity induced by behavioral treatment (1985) (2)
Central visual, auditory, somatosensory, gustatory (1989) (2)
Differential Infectivity Following Basal Ganglia Administration of Differing AAV Serotypes in Nonhuman Primates (2009) (2)
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson’s Disease (2020) (2)
GDNF Therapy: Can We Make It Work? (2021) (2)
Effects of over-stimulation by glucose on pancreatic beta-cell functioning : studies in vitro with diazoxide (1999) (1)
New Mouse Models for Studying Postnatal Role of GDNF In Vivo (2010) (1)
Possible regeneration of gamma-aminobutyric acid-containing fibres into irides transplanted into the central nervous system. (1976) (1)
Fetal Striatal Transplants in the Ibotenate Lesioned Striatum of Adult Rats: Specific Anatomical Integration between Graft and Host (1990) (1)
Connections, Cognition and Alzheimer’s Disease (1997) (1)
Effects of GDNF on Nigrostriatal Dopamine Neurons (2002) (1)
Disease, transplantation and regeneration Editorial overview (1992) (1)
Latent Autoimmune Diabetes in Adults: Background, Safety and Feasibility of an Ongoing Pilot Study With Intra-Lymphatic Injections of GAD-Alum and Oral Vitamin D (2022) (1)
Gene transfer in situ and in cells for intracerebral transplantation (1993) (1)
Introduction to Part I (2021) (1)
Long-term Locomotor and Cognitive Deficits in Rats with 6-OHDA Lesions of the VTA: A Model for Transplantation Studies (1986) (1)
Bronchial Reactivity, Smoking, and Alpha1-Antitrypsin (2015) (1)
Letter to the Editor From Grill et al: “Islet Function and Insulin Sensitivity in Latent Autoimmune Diabetes in Adults Taking Sitagliptin: A Randomized Trial” (2021) (1)
Increase in rabbit hypothalamic histidine decarboxylase activity after oophorectomy and thyroidectomy (1972) (1)
Restorative Therapies for Parkinson's Disease: Current Status and Future Perspectives (2006) (1)
Recent developments in aldehyde-induced monoamine fluorescence: The aluminum-formaldehyde (ALFA) method applied to immature and adult central nervous tissue (1981) (1)
Corrigendum to “Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation” [Biochim. Biophys. Acta 1801 (2010) 191–197] (2011) (1)
Primary and stem cell therapies for brain repair (2012) (1)
New aspects on factors determining the sensitivity of the formaldehyde and glyoxylic acid fluorescence histochemical methods for monoamines (2004) (1)
Growth of Central NA Fibres Into Chronically Denervated Irides (1975) (0)
From modeling to treating Parkinson’s disease:the importance of viral vectors (2015) (0)
Reinnervation of Irides Transplanted to the Caudal Diencephalon (1975) (0)
Cell Replacement Therapy: Parkinson’s Disease (2009) (0)
A TRPM 4 Inhibitor 9-Phenanthrol Inhibits Glucose-and Glucagon-Like Peptide 1-Induced Insulin Secretion from Rat Islets of Langerhans (2017) (0)
Reversal of L-DOPA-induced dyskinesia by recombinant AAV-mediated gene transfer (2004) (0)
Reversal of age-dependent cholinergic neuron atrophy and learning impairments by neurotrophic factors (1995) (0)
Reinnervation of Transplanted Irides by Central DA and IA Fibres (1975) (0)
Repair mechanisms during neuronal regeneration (1987) (0)
Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system (2004) (0)
Morphological and behavioral changes following neural grafting in rats with ibotenate lesions of the anteromedial caudate putamen (1985) (0)
PL.02.01 Novel therapeutic targets for neuroprotection and disease modification in Parkinson's disease (2013) (0)
Vascularization and Survival of Irides Transplanted to the Caudal Diencephalon and to the Anterior Chamber of the Eye (1975) (0)
AAV-mediated overexpression of alpha-synuclein in midbrain dopamine neurons of Synapsin III knockout mice reveals novel molecular features involved in Parkinson's disease pathology. (2016) (0)
Neuroprotective and Behavioral Efficacy of NGF-transfected Hippocampal Progenitor Cells Transplanted into the Peri-injured Cortex of Rats after Lateral Fluid Percussion Brain Injury (1998) (0)
Dopamine‐containing neurons in the spinal cord: Anatomy and some functional aspects (1983) (0)
Hippocampal deafferentation: transplant-derived reinnervation and functional recovery. (1982) (0)
Nigral and Striatal Grafts to the Lesioned Neostriatum: Models of Graft Function (1989) (0)
Brain stem control of spinal mechanisms : proceedings of the 1st Eric K. Fernström Symposium, held in Lund (Sweden) on 10-13 November 1981 (1982) (0)
Role of TRPM 5 channel in insulin secretion from rat β-cells (2017) (0)
Correction for Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells (2010) (0)
Marios Politis Parkinson ' s Patients Treated with Dopamine Grafts Serotonin Neuron Loss and Nonmotor Symptoms Continue in (2012) (0)
New fluorophore-forming reactions for histochemical visualization of N-acetylated and tertiary indolamines using glyoxylic acid, aluminum-formaldehyde and trifluoroacetic acid anhydride as reagents (2004) (0)
Problems specifically related to grafting to the aged brain (1985) (0)
Grafts of serotonin neurons in the hippocampus immunohistochemical and biochemical analyses (1987) (0)
Reply: Rate of progression determines the clinical outcome after neural transplantation in Parkinson's disease (2006) (0)
Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson’s disease (2015) (0)
Self-stimulation from substantia nigra transplants: Evidence of specific dopaminergic activation of the striatum (1982) (0)
Politis Patients with Neural Transplants Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson ' s (2011) (0)
Apolipoprotein E and Alzheimer’s Disease (1996) (0)
Gene Therapy in Animal Models of Neurological Disorders (1992) (0)
Regeneration of the bulbospinal serotonin system after 5,6- or 5,7-dihydroxytryptamine in the rat. (1975) (0)
P.208 BDNF overexpression exacerbates D1R agonist-induced dyskinesia in hemiparkinsonian rats via D1R-D3R heteromers formation (2020) (0)
CONDITIONS FOR NEURONAL SURVIVAL (1987) (0)
Glial Cell Derived Neurotrophic Factor Does not Provide Neuroprotection Against Alpha-Synuclein-Induced Toxicity in a Rat Model of Parkinson's Disease (2010) (0)
Presenilins and Alzheimer’s Disease (1998) (0)
Gene therapy for Parkinson's disease (2008) (0)
Fatty acids and beta-cell function (1997) (0)
Reduced tyrosine hydroxylase activity in guinea-pig uterus during pregnancy. (1977) (0)
Behavioural Compensation after Dopamine Grafts in Brain (1986) (0)
Gene therapy for Parkinson's disease: now getting closer (2005) (0)
SUBSTANTIA N I G R A IN RATS SUBJECTED TO 6-OHDA LESIONS OF THE N I G R O S T R I A T A L PATHWAY. I. U N I L A T E R A L LESIONS (2002) (0)
Restorative cell and gene therapies for Parkinson's disease. (2023) (0)
Functional integration of neural precursor cells in the cortex and hippocampus after transplantation into the neonatal rat brain (2002) (0)
S.16.03 Neural stem cell and brain repair (2004) (0)
FETAL BRAIN GRAFTS AND PARKINSONS-DISEASE - RESPONSE (1990) (0)
Profile of Anders Bjorklund. Interview by Beth Azar. (2012) (0)
810 – NGF IN AXONAL REGENERATION OF CENTRAL AND PERIPHERAL MONOAMINE NEURONS (1977) (0)
Recent advances in Parkinson's disease (2010) (0)
Transplantation to the Damage Adult Hippocampal Formation (1986) (0)
The Role of Norepinephrine Neurons in Motor Symptoms of Parkinson's Disease and Development of L-DOPA-Induced Dyskinesia (2010) (0)
Monoamine-like substances in the pituitary gland. (1970) (0)
Third International Congress of Histochemistry and Cytochemistry: August 18–22, 1968, New York, N.Y. (1968) (0)
Preface: The evolving scenario of Parkinson's research. (2020) (0)
Neuronal replacement by intracerebral neural transplants (1991) (0)
Cell Transplantation for Parkinson ’ s Disease in Lund . Some personal recollections (2013) (0)
Effects of Dopamine-Rich Grafts on Sensorimotor Impairments in Dopamine-Depleted Rats (1987) (0)
a-synucleinopathy induced by recombinant AAV vector-mediated overexpression of human a-synuclein : A new primate model of Parkinson ’ s disease (2002) (0)
hESC-Derived Dopaminerg ic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson ’ s Disease Graphical (0)
Embryonic dopaminergic precursors can be isolated at different states of differentiation and function upon grafting into an animal model of Parkinson’s disease (2008) (0)
Adult Bone Marrow-Derived Cell Fusion with Cardiomyocytes and Purkinje Neurons in Response to Irradiation but Not in Steady State. (2004) (0)

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