Anders Rane
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(Suggest an Edit or Addition)Anders Rane's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose (2009) (629)
- The largest prospective warfarin-treated cohort supports genetic forecasting. (2009) (551)
- Use of doping agents, particularly anabolic steroids, in sports and society (2008) (328)
- Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance. (1977) (311)
- Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism. (2006) (284)
- Caffeine intake and the risk of first-trimester spontaneous abortion. (2000) (255)
- Plasma protein binding of diphenylhydantoin in man; Interaction with other drugs and the effect of temperature and plasma dilution (1970) (246)
- Induction of CYP2D6 in pregnancy (1997) (229)
- Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation (2003) (225)
- Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing (2010) (223)
- Influence of CYP2C9 genotype on warfarin dose requirements—a systematic review and meta-analysis (2009) (222)
- Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver. (1994) (221)
- Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. (1997) (219)
- Prednisolone excretion in human milk. (1985) (218)
- Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz (2006) (206)
- Cytochromes P450 and MDR1 mRNA expression along the human gastrointestinal tract. (2005) (195)
- The metabolism and bioavailability of morphine in patients with severe liver cirrhosis. (1990) (166)
- Doping test results dependent on genotype of uridine diphospho-glucuronosyl transferase 2B17, the major enzyme for testosterone glucuronidation. (2008) (161)
- The presence of a monooxygenase system in human fetal liver microsomes. (1970) (155)
- Relation between plasma concentration of indomethacin and its effect on prostaglandin synthesis and platelet aggregation in man (1978) (148)
- Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms. (2002) (141)
- SFINX—a drug-drug interaction database designed for clinical decision support systems (2009) (135)
- Autoinduction of carbamazepine metabolism in children examined by a stable isotope technique (1980) (134)
- Plasma binding and disposition of furosemide in the nephrotic syndrome and in uremia (1978) (125)
- Acetaminophen: potentially toxic metabolite formed by human fetal and adult liver microsomes and isolated fetal liver cells. (1979) (123)
- Pregnancy‐induced increase in metoprolol metabolism (1985) (122)
- Polymorphisms in NAT2, CYP2D6, CYP2C19 and GSTP1 and their association with prostate cancer. (1999) (121)
- Acetyltransferase in humans: development and tissue distribution. (1986) (120)
- The anti-doping hot-line, a means to capture the abuse of doping agents in the Swedish society and a new service function in clinical pharmacology (2003) (118)
- Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction. (2003) (116)
- Pharmacogenetics of cyclophosphamide in patients with hematological malignancies. (2006) (111)
- Plasma protein binding of diphenylhydantoin in normal and hyperbilirubinemic infants. (1971) (104)
- The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme. (1989) (100)
- Human brain metabolism of morphine and naloxone (1988) (100)
- EXPRESSION OF CYP3A ISOFORMS AND P‐GLYCOPROTEIN IN HUMAN STOMACH, JEJUNUM AND ILEUM (2007) (98)
- SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density. (2006) (95)
- A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid. (1997) (95)
- Kinetics of carbamazepine and its 10,11‐epoxide metabolite in children (1976) (93)
- Morphine glucuronidation in human fetal and adult liver (2004) (92)
- A Pharmacometric Model Describing the Relationship Between Warfarin Dose and INR Response With Respect to Variations in CYP2C9, VKORC1, and Age (2010) (92)
- Clinical Pharmacokinetics in Infants and Children (1976) (88)
- Dose requirement and prolactin elevation of antipsychotics in male and female patients with schizophrenia or related psychoses. (2001) (87)
- Human and rodent type 1 11β-hydroxysteroid dehydrogenases are 7β-hydroxycholesterol dehydrogenases involved in oxysterol metabolism (2004) (87)
- Differential foetal development of the O- and N-demethylation of codeine and dextromethorphan in man. (1991) (83)
- Deletion polymorphism of the UGT2B17 gene is associated with increased risk for prostate cancer and correlated to gene expression in the prostate (2008) (83)
- Morphine metabolism in children. (1989) (82)
- Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: Relationship to the presence of immunoidentified cytochrome P‐450IID1 (1990) (82)
- Several‐fold increase in risk of overanticoagulation by CYP2C9 mutations (2005) (81)
- Plasma kinetics of carbamazepine and its epoxide metabolite in man after single and multiple doses (1975) (78)
- Effects of CYP2C9 polymorphisms on the pharmacokinetics of R- and S-phenprocoumon in healthy volunteers. (2004) (78)
- 5alpha-reductase 2 polymorphisms as risk factors in prostate cancer. (2002) (76)
- Detection of cytochrome P450 mRNA transcripts in prostate samples by RT‐PCR (2001) (76)
- Morphine Metabolism in Children (1990) (74)
- Patient-controlled analgesia (PCA) with codeine for postoperative pain relief in ten extensive metabolisers and one poor metaboliser of dextromethorphan. (1995) (73)
- Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function (2013) (71)
- Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro (2004) (70)
- Incidence and predictors of severe bleeding during warfarin treatment (2008) (70)
- Carbamazepine therapy in trigeminal neuralgia: clinical effects in relation to plasma concentration. (1980) (69)
- Paediatric adverse drug reactions reported in Sweden from 1987 to 2001 (2005) (69)
- Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy (2011) (69)
- The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men. (2007) (69)
- The influence of indomethacin on the pharmacokinetics, diuretic response and hemodynamics of furosemide in the dog. (1978) (66)
- Development of the glucuronyltransferase and sulphotransferase towards 2-naphthol in human fetus. (1989) (64)
- Diphenylhydantoin Binding to Proteins in Plasma and Its Dependence on Free Fatty Acid and Bilirubin Concentration in Dogs and Newborn Infants (1975) (61)
- Genetic aspects of epitestosterone formation and androgen disposition: influence of polymorphisms in CYP17 and UGT2B enzymes (2008) (60)
- Identification and Phenotype Characterization of Two CYP3A Haplotypes Causing Different Enzymatic Capacity in Fetal Livers (2005) (60)
- The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women. (2002) (60)
- DNA methylation dynamics in the hepatic CYP3A4 gene promoter. (2012) (57)
- Long term perturbation of endocrine parameters and cholesterol metabolism after discontinued abuse of anabolic androgenic steroids (2011) (57)
- Effect of renal impairment on the pharmacokinetics of bupropion and its metabolites. (2007) (56)
- Polymorphisms of NAT2 in relation to sulphasalazine-induced agranulocytosis. (2000) (56)
- Rapid single-nucleotide polymorphism detection of cytochrome P450 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genes for the warfarin dose adjustment by the SMart-amplification process version 2. (2009) (54)
- Genotypic and phenotypic determination of polymorphic glutathione transferase T1 in a Swedish population. (1995) (54)
- Increased oral clearance of metoprolol in pregnancy (2004) (54)
- The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver (1993) (54)
- The impact of CYP2C9 genetics and oral contraceptives on cytochrome P450 2C9 phenotype. (2004) (53)
- The UGT2B17 gene deletion is not associated with prostate cancer risk (2008) (53)
- Phenytoin Excretion in Human Breast Milk and Plasma Levels in Nursed Infants (1982) (53)
- A supraphysiological dose of testosterone induces nitric oxide production and oxidative stress (2014) (53)
- Human fetal and adult liver metabolism of ethylmorphine. Relation to immunodetected cytochrome P-450 PCN and interactions with important fetal corticosteroids. (1989) (52)
- Widespread off-label prescribing of topical but not systemic drugs for 350,000 paediatric outpatients in Stockholm (2003) (51)
- Dopamine sulphotransferase is better developed than p-nitrophenol sulphotransferase in the human fetus. (1991) (51)
- Drug metabolism in the human fetus and newborn infant. (1972) (51)
- Effects of the Antifungals Voriconazole and Fluconazole on the Pharmacokinetics of S-(+)- and R-(−)-Ibuprofen (2006) (51)
- Caffeine Metabolism and the Risk of Spontaneous Abortion of Normal Karyotype Fetuses (2001) (50)
- Radical prostatectomy: Influence on serum and urinary androgen levels (2009) (50)
- Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study (2005) (49)
- Dextromethorphan: polymorphic serum pattern of the O-demethylated and didemethylated metabolites in man. (1989) (49)
- Doping Test Results Dependent on Genotype of UGT2B17, the Major Enzyme for Testosterone Glucuronidation (2008) (48)
- Drugs and fetal metabolism (1973) (48)
- Decreased plasma protein binding of phenytoin in patients on valproic acid. (1979) (48)
- Properties of hydroxylase systems in the human fetal liver active on free and sulfoconjugated steroids. (1975) (48)
- Cocaine metabolism in human fetal and adult liver microsomes is related to cytochrome P450 3A expression. (2000) (46)
- Cytosolic epoxide hydrolase in humans: development and tissue distribution (2004) (46)
- Sulphation and glucuronidation of ritodrine in human foetal and adult tissues (2004) (46)
- Inhibition of phenol sulfotransferase (SULT1A1) by quercetin in human adult and foetal livers (2002) (45)
- Androgen sulfation in healthy UDP-glucuronosyl transferase 2B17 enzyme-deficient men. (2011) (44)
- Tricyclic antidepressants inhibit opioid receptor binding in human brain and hepatic morphine glucuronidation. (1994) (44)
- Biosynthesis of epoxyeicosatrienoic acids varies between polymorphic CYP2C enzymes. (2005) (43)
- Substantial advantage of a combined Bayesian and genotyping approach in testosterone doping tests (2009) (43)
- Glutathione S-transferase in humans: development and tissue distribution (2004) (42)
- Regulation and expression of human CYP7B1 in prostate: Overexpression of CYP7B1 during progression of prostatic adenocarcinoma (2007) (42)
- Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome P450 genes by ciprofloxacin (2003) (42)
- Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation (2009) (41)
- Amphetamine secretion in breast milk (2004) (41)
- The liver microsomal monooxygenase system in the human fetus: Distribution in different centrifugal fractions (1972) (41)
- Cytochrome P450 isoforms in human fetal tissues related to phenobarbital-inducible forms in the mouse. (1993) (40)
- Dietary caffeine as a probe agent for assessment of cytochrome P4501A2 activity in random urine samples. (1999) (40)
- Independent patterns of cytochrome P450 gene expression in liver and blood in patients with suspected liver disease (2001) (40)
- Dual use of anabolic-androgenic steroids and narcotics in Sweden. (2010) (39)
- Intra-individual variation and sex differences in gene expression of cytochromes P450 in circulating leukocytes (2002) (39)
- Determination of phenprocoumon, warfarin and their monohydroxylated metabolites in human plasma and urine by liquid chromatography-mass spectrometry after solid-phase extraction. (2004) (38)
- Two distinct forms of glutathione transferase from human foetal liver. Purification and comparison with isoenzymes isolated from adult liver and placenta. (1986) (38)
- Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients. (2006) (38)
- Recruitment to doping and help-seeking behavior of eight female AAS users (2016) (37)
- Genetic polymorphisms of cytochrome P450 2C9 causing reduced phenprocoumon (S)-7-hydroxylation in vitro and in vivo (2004) (37)
- Thiopurine methyltransferase in humans: development and tissue distribution. (1991) (36)
- Clindamycin passage into human milk. (1982) (36)
- Morphine sulphation in children. (1990) (36)
- Correlation between circulatory, local prostatic, and intra‐prostatic androgen levels (2011) (35)
- Morphine glucuronidation in the rhesus monkey: a comparative in vivo and in vitro study. (1984) (35)
- Transfer of labetalol into amniotic fluid and breast milk in lactating women (2004) (35)
- Androgens and doping tests: genetic variation and pit-falls. (2012) (35)
- Metabolism of styrene oxide in different human fetal tissues. (1982) (35)
- PLASMA PROTEIN BINDING, PLASMA CONCENTRATIONS, AND EFFECTS OF DIPHENYLHYDANTOIN IN MAN * (1971) (34)
- Glutathione S-transferases in human fetal liver. (1981) (34)
- Increased liability of tramadol–warfarin interaction in individuals with mutations in the cytochrome P450 2D6 gene (2004) (34)
- Messenger Ribonucleic Acid Levels of Steroid 5α-Reductase 2 in Human Prostate Predict the Enzyme Activity1 (2001) (33)
- Dose-dependent testosterone sensitivity of the steroidal passport and GC-C-IRMS analysis in relation to the UGT2B17 deletion polymorphism. (2015) (33)
- Genetic polymorphism of cytochrome P450s and P‐glycoprotein in the Finnish population (2007) (33)
- Presystemic glucuronidation of morphine in humans and rhesus monkeys: subcellular distribution of the UDP-glucuronyltransferase in the liver and intestine. (1986) (33)
- Differential gene expression of steroid 5 alpha-reductase 2 in core needle biopsies from malignant and benign prostatic tissue. (1997) (32)
- Glucuronidation of Morphine in Human Liver and Interaction with Oxazepam (1982) (32)
- Tissue Distribution and Relative Gene Expression of UDP-Glucuronosyltransferases (2B7, 2B15, 2B17) in the Human Fetus (2013) (31)
- Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y). (2007) (31)
- Long term high dose morphine, ketamine and midazolam infusion in a child with burns. (1990) (31)
- A novel polymorphism in the 17β-hydroxysteroid dehydrogenase type 5 (aldo-keto reductase 1C3) gene is associated with lower serum testosterone levels in caucasian men (2007) (31)
- Ethosuximide in human milk and in plasma of a mother and her nursed infant. (1981) (30)
- Expression of CYP3A4 and CYP3A7 in Human Foetal Tissues and its Correlation with Nuclear Receptors (2015) (30)
- Plasma concentrations of 5‐(4‐hydroxyphenyl)‐5‐phenylhydantoin in phenytoin‐treated patients (1977) (30)
- Single dose testosterone increases total cholesterol levels and induces the expression of HMG CoA Reductase (2012) (30)
- Urinary excretion of diphenylhydantoin metabolites in newborn infants. (1974) (30)
- Loading and conventional dose therapy with phenytoin in children: Kinetic profile of parent drug and main metabolite in plasma (1976) (30)
- Low Vitamin D Levels and Genetic Polymorphism in the Vitamin D Receptor are Associated with Increased Risk of Statin‐Induced Myopathy (2016) (30)
- p-Toluenesulfonyl Chloride as an Activating Agent of Agarose for the Preparation of Immobilized Affinity Ligands and Proteins. Optimization of Conditions for Activation and Coupling. (1981) (29)
- Bioavailability of testosterone enanthate dependent on genetic variation in the phosphodiesterase 7B but not on the uridine 5′-diphospho-glucuronosyltransferase (UGT2B17) gene. (2011) (29)
- Drug metabolizing enzymes in lymphocytes (1999) (29)
- Lamotrigine and toxic epidermal necrolysis (1996) (28)
- Phenotyping of drug metabolism in infants and children: potentials and problems. (1999) (28)
- Sulphotransferase and its substrate: adenosine-3'-phosphate-5'-phosphosulphate in human fetal liver and placenta. (1990) (28)
- Effect of caffeine intake 12 or 24 hours prior to melatonin intake and CYP1A2*1F polymorphism on CYP1A2 phenotyping by melatonin. (2006) (28)
- Expression of cytochromes P450 3A and P-glycoprotein in human large intestine in paired tumour and normal samples. (2007) (28)
- Glutathione S-epoxidetransferase in the human placenta at different stages of pregnancy. (1981) (28)
- Evidence for a role of cytochrome P450 2D6 and 3A4 in ethylmorphine metabolism. (1995) (27)
- A Novel Polymorphic Cytochrome P450 Formed by Splicing of CYP3A7 and the Pseudogene CYP3AP1* (2005) (27)
- Sensitivity of doping biomarkers after administration of a single dose testosterone gel. (2018) (26)
- Amphetamine secretion in breast milk (2004) (25)
- Organ distribution of glutathione transferase isoenzymes in the human fetus: differences between liver and extrahepatic tissues. (1986) (25)
- Plasma concentration — effect relationship of metoprolol during and after pregnancy (2004) (24)
- Oxidative drug metabolism in the perinatal rabbit liver and placenta. A biochemical and morphologic study. (1973) (23)
- Effect of cyclophosphamide on gene expression of cytochromes p450 and beta-actin in the HL-60 cell line. (2002) (23)
- Differential effects of neuroleptic agents on hepatic cytochrome P-450 isozymes in the male rat. (1996) (23)
- Human adult and foetal liver sulphotransferases: inhibition by mefenamic acid and salicylic acid (2001) (23)
- Epoxide hydrolase in human fetal liver. (1983) (22)
- Valpromide inhibits human epoxide hydrolase. (1986) (22)
- Rate of metabolism of tremorine and oxotremorine in rats and mice. (1968) (22)
- Ethylmorphine O‐deethylation cosegregates with the debrisoquin genetic metabolic polymorphism (1992) (21)
- Effects of different doses of testosterone on gonadotropins, 25-hydroxyvitamin D3, and blood lipids in healthy men (2014) (21)
- Human liver morphine UDP‐glucuronyl transferase enantioselectivity and inhibition by opioid congeners and oxazepam (1988) (21)
- Glutathione-S-transferase in human fetal liver. (1981) (21)
- Pharmacogenetics of Anticoagulants (2010) (21)
- Effect of voriconazole on the pharmacokinetics of diclofenac (2007) (21)
- VALPROMIDE/CARBAMAZEPINE AND RISK OF TERATOGENICITY (1985) (21)
- A functional C–G polymorphism in the CYP7B1 promoter region and its different distribution in Orientals and Caucasians (2004) (21)
- Glutathione and gamma-glutamyl cycle enzymes in human fetal liver. (1981) (21)
- Sex differences and endocrine regulation of morphine oxidation in rat liver. (1990) (20)
- Roles of different CYP enzymes in the formation of specific fluvastatin metabolites by human liver microsomes. (2009) (20)
- Renal glucuronidation of morphine in the human foetus. (2009) (20)
- Relation of naproxen kinetics to effect on platelet prostaglandin release in men and dysmenorrheic women (1981) (20)
- Gene expression of cytochrome P450 1B1 and 2D6 in leukocytes in human pregnancy. (2003) (19)
- Testosterone challenge and androgen receptor activity in relation to UGT2B17 genotypes (2013) (19)
- Monoclonal antibody directed detection of cytochrome P-450 (PCN) in human fetal liver. (1988) (19)
- Thiol methyltransferase in humans: development and tissue distribution. (1991) (19)
- miRNA‐27b levels are associated with CYP3A activity in vitro and in vivo (2015) (19)
- A conspicuous down-regulating effect of morphine on essential steroid hydroxylation reactions and certain drug N-demethylations (1992) (18)
- SULT2A1 Gene Copy Number Variation is Associated with Urinary Excretion Rate of Steroid Sulfates (2013) (18)
- Conjugation of benzoic acid with glycine in the human fetal and adult liver and kidney. (1991) (18)
- Clonazepam serum protein binding during development (1984) (18)
- Metabolic interaction between morphine and various benzodiazepines. (2009) (18)
- Genetic variation in androgen disposition: implications in clinical medicine including testosterone abuse (2009) (18)
- CYP1A2*1F Polymorphism Decreases Clinical Response to Clozapine in Patients with Schizophrenia (2011) (18)
- Detoxification of Styrene Oxide by Human Liver Glutathione Transferase (1987) (18)
- Metabolic interaction between morphine and naloxone in human liver. A common pathway of glucuronidation? (1989) (18)
- Selective effects of somatostatin analogs on human drug‐metabolizing enzymes (1998) (17)
- Epoxide hydrolase in human placenta at different stages of pregnancy. (1983) (17)
- Comparison of different clearance estimates for metoprolol in the rhesus monkey. (1984) (17)
- Sulfotransferase in humans: development and tissue distribution. (1988) (16)
- Formation of a 16,17‐trans‐glycolic metabolite from a 16‐dehydro‐androgen in human fetal liver microsomes (1973) (16)
- Statin-induced myopathy in a usual care setting—a prospective observational study of gender differences (2016) (16)
- Uridine 5′ — Diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta (2000) (16)
- Inhibition of morphine glucuronidation by oxazepam in human fetal liver microsomes. (1981) (16)
- CYP2C8 and CYP2C9 mRNA expression profile in the human fetus (2014) (16)
- Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism? (1995) (16)
- N‐oxidation of a tertiary amine (N,N‐dimethylaniline) by human fetal liver microsomes (1974) (15)
- Polymorphic acetylation of 7-amino-clonazepam in human liver cytosol. (1984) (15)
- Biotransformation of benzo[a]pyrene and 7-ethoxyresorufin and heme-staining proteins in microsomes from human fetal liver and placenta. (1983) (15)
- Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat (2005) (15)
- Atorvastatin Treatment Induces Uptake and Efflux Transporters in Human Liver (2013) (15)
- Genetic variation, expression and ontogeny of sulfotransferase SULT2A1 in humans (2015) (15)
- N-demethylation of ethylmorphine in pregnant and non-pregnant women and in men: an evaluation of the effects of sex steroids. (1992) (15)
- Beneficial vasoactive endothelial effects of fluvastatin: focus on prostacyclin and nitric oxide (2011) (15)
- Caffeine intake and the risk of spontaneous abortion. (2003) (15)
- Distribution of UDP-glucuronyltransferase in different human foetal tissues. (1982) (15)
- Quantitation of clonazepam and its 7-amino and 7-acetamido metabolites in plasma by high-performance liquid chromatography. (1984) (15)
- Gene expression of cytochromes P450 in liver transplants over time (2004) (14)
- Internet based clinical trial protocols -- as applied to a study of warfarin pharmacogenetics. (2004) (14)
- Cytosolic epoxide hydrolase in fetal and adult human liver (1983) (14)
- Doping and Genetic Testing: Sex Difference in UGT2B15 Expression, Testosterone Glucuronidation Activity and Urinary Testosterone/ Epitestosterone Glucuronide Ratio (2012) (14)
- Determination of codeine and its metabolites in human blood plasma and in microsomal incubates by high-performance liquid chromatography with ultraviolet detection. (1989) (14)
- Disposition of placentally transferred carbamazepine (Tegretol®) in the newborn (1975) (13)
- The Anion Radical-Proton Donor Complex Mechanism of the Electrohydrodimerization of Diethyl Fumarate in N,N-Dimethylformamide. (1981) (13)
- The postoperative pharmacokinetics of codeine (2004) (13)
- Morphine metabolism in mouse brain. (1986) (13)
- Expression of UGT2B7 is driven by two mutually exclusive promoters and alternative splicing in human tissues: changes from prenatal life to adulthood and in kidney cancer (2013) (13)
- Ultrafiltration compared with equilibrium dialysis in the determination of unbound phenytoin in plasma. (1985) (13)
- Messenger ribonucleic acid levels of steroid 5 alpha-reductase 2 in human prostate predict the enzyme activity. (2001) (13)
- Association of cytochrome P450 1B1 polymorphism with first-trimester miscarriage. (2006) (13)
- The monooxygenase system in the human fetal liver: subcellular distribution and studies on in vitro metabolism of aniline. (1971) (13)
- Pharmacokinetics of 250 μg anti‐D IgG in the third trimester of pregnancy: An observational study (2012) (13)
- Nuclear epoxide hydrolase in the human fetal and adult liver. (1984) (12)
- Metabolism of desmethylimipramine in human foetal and adult liver microsomes. (2009) (12)
- Phenytoin enhances epoxide metabolism in human fetal liver cultures. (1985) (12)
- Comparison of human fetal hepatic and adrenal cytochrome P450 activities with some major gestational steroids and ethylmorphine as substrates (1992) (11)
- Plasma Protein Binding of Clonazepam in Hepatic and Renal Insufficiency and After Hemodialysis (1987) (11)
- Male Anabolic Androgenic Steroid Users with Personality Disorders Report More Aggressive Feelings, Suicidal Thoughts, and Criminality (2020) (11)
- Kinetics of phenytoin in pregnant and non-pregnant rats. (2009) (11)
- Electrode Mechanism Analysis by Linear Sweep Voltammetry. II. Application of Derivative Cyclic Voltammetry. (1981) (11)
- Expression of cytochrome P450 and MDR1 in patients with proctitis (2007) (11)
- Cytochrome P-450 in human fetal liver microsomes. (1971) (11)
- Effects of Angiotensin II Receptor Blockers on Metabolism of Arachidonic Acid via CYP2C8. (2015) (11)
- Growth hormone replacement therapy induces codeine clearance (2002) (11)
- The sensitivity to noxious heat in relation to brain and liver opioid glucuronidation in inbred strains of mice (1989) (11)
- Metabolism of ethylmorphine and aniline in human fetal liver. (1972) (11)
- Styrene oxide metabolism in rhesus monkey liver: enzyme activities in subcellular fractions and in isolated hepatocytes. (1983) (11)
- Implication of Human UGT2B7, 2B15, and 2B17 in 19-Norandrosterone Metabolism (2013) (10)
- Disposition of carbamazepine and its 10,11-epoxide metabolite in the isolated perfused rat liver. (1977) (10)
- Angiotensin II Receptor Blockers Inhibit the Generation of Epoxyeicosatrienoic Acid from Arachidonic Acid in Recombinant CYP2C9, CYP2J2 and Human Liver Microsomes (2017) (10)
- STRUCTURE OF CHALOXONE, ISOLATED FROM A CHALARA SP (1981) (10)
- Mechanisms of the Electrohydrodimerization of Activated Olefins. II. The Radical--Substrate Coupling Mechanism. (1981) (10)
- Prenatal expression of thioredoxin reductase 1 (TRXR1) and microsomal glutathione transferase 1 (MGST1) in humans (2014) (10)
- Non-Steroidal Anti-Inflammatory Drugs Do Not Influence the Urinary Testosterone/Epitestosterone Glucuronide Ratio (2013) (10)
- Detection of morphine-3-sulfate and morphine-6-sulfate in human urine and plasma, and formation in liver cytosol (2014) (10)
- Sulphate and glucuronic acid conjugation of harmol in human fetal and adult liver tissue. (1982) (10)
- Human fetal liver cultures: basal activities and inducibility of epoxide hydrolases and aryl hydrocarbon hydroxylase. (1984) (10)
- Intestinal and hepatic morphine glucuronidation in immature and pregnant rats. (1981) (9)
- Statin‐induced Myopathy and Ubiquinone Levels in Serum – Results from a Prospective, Observational Study (2015) (9)
- Perturbation of the Hematopoietic Profile by Anabolic Androgenic Steroids (2014) (9)
- Insulin-like growth factor 1 (IGF-I) effects on sex-specific cytochrome P450 enzymes in normal and hypophysectomised male rats. (1998) (9)
- The Inhibitory Effect of Telmisartan on the Metabolism of Arachidonic Acid by CYP2C9 and CYP2C8: An in Vitro Study. (2017) (9)
- Kinetics of placentally transferred phenytoin and its p-hydroxylated metabolites in newborn infants. (1979) (9)
- Fatal Hepatic Failure in a Child Treated with Phenytoin and Valproic Acid (1982) (9)
- The rhesus monkey as a model for studies of pregnancy induced changes in metoprolol metabolism. (1990) (9)
- Developmental aspects of pharmacokinetics. (2009) (9)
- Valpromide but not sodium hydrogen divalproate inhibits epoxide hydrolase in human liver. (1987) (8)
- Digoxin and Phenytoin analyses as part of consultations in clinical pharmacology: a study on the use of drugs. (1981) (8)
- Quantitation of cytochrome P450 mRNAs in patients with suspected liver diseases as assessed by reverse transcriptase-polymerase chain reaction. (1999) (8)
- Disposition of morphine-3-glucuronide in the pregnant rhesus monkey. (1990) (8)
- Epoxide hydrolase and aryl hydrocarbon hydroxylase in human fetal tissues: activities in nuclear and microsomal fractions and in isolated hepatocytes. (1983) (8)
- Pregnancy greatly affects the steroidal module of the Athlete Biological Passport. (2018) (8)
- Endocrine and adrenergic pharmacological intervention in diseases of the prostate. (1998) (7)
- THE IMPACT OF CYP 2 C 9 GENETICS AND ORAL CONTRACEPTIVES ON CYTOCHROME P 450 2 C 9 PHENOTYPE (2004) (7)
- Conjugation of styrene oxide by the basic and acidic forms of glutathione transferase in the human fetal liver. (1988) (7)
- Presence of epoxide hydrolase and glutathione S-transferase in human pulmonary alveolar macrophages (2004) (7)
- Purification of Glutamine Synthetase from Rhodospirillum rubrum by Affinity Chromatography. (1981) (7)
- Isolation of nuclear fractions from human fetal tissues. Ultrastructure and presence of epoxide hydrolase and aryl hydrocarbon hydroxylase. (1985) (7)
- Clonazepam and 7‐Aminoclonazepam in Human Plasma (1991) (7)
- 7-Ethoxycoumarin and 7-ethoxyresorufin O-deethylase in human foetal and adult liver: studies with monoclonal antibodies. (1988) (7)
- Atypical excretion profile and GC/C/IRMS findings may last for nine months after a single dose of nandrolone decanoate (2016) (6)
- Simple and Exact Determination of Apparent Activation Energies of Electrode Processes. (1981) (6)
- Simultaneous Determination Method of Epoxyeicosatrienoic Acids and Dihydroxyeicosatrienoic Acids by LC-MS/MS System. (2015) (6)
- Plasma concentrations of diphenylhydantoin in young infants (1970) (6)
- Drug−drug Interaction between Losartan and Paclitaxel in Human Liver Microsomes with Different CYP2C8 Genotypes (2015) (6)
- Nitroreduction of clonazepam in human foetal liver microsomes and hepatocyte cultures. (1984) (6)
- Plasma concentration-effect relationship of theophylline in treatment of apnea in preterm infants (1980) (6)
- Perinatal opiate exposure. Effects on metabolism of xenobiotics and steroids in adult rat liver. (1989) (6)
- Discordant genotyping results using DNA isolated from anti-doping control urine samples. (2017) (5)
- Co-administration of Fluvastatin and CYP3A4 and CYP2C8 Inhibitors May Increase the Exposure to Fluvastatin in Carriers of CYP2C9 Genetic Variants. (2017) (5)
- Apparently normal phenytoin metabolism in a patient with phenytoin-induced rash and lymphadenopathy. (1987) (5)
- DOPAMINE SULFOTRANSFERASE IS BETTER DEVELOPED THAN PARA-NITROPHENOL SULFOTRANSFERASE IN THE HUMAN FETUS (1991) (5)
- Genetic Variation in SLCO2B1 is Associated with Serum Levels of Testosterone and its Metabolites Prior to and Two Days after Testosterone Administration (2012) (5)
- Vitamin D receptor rs2228570 polymorphism is associated with LH levels in men exposed to anabolic androgenic steroids (2018) (5)
- Morphine-induced effects on hepatic metabolism in the male rat depends on an intact pituitary gland. (1990) (5)
- Losartan competitively inhibits CYP2C8-dependent paclitaxel metabolism in vitro. (2014) (5)
- Codeine influences the serum and urinary profile of endogenous androgens but does not interact with the excretion rate of administered testosterone. (2018) (5)
- Ontogenic development of 7-ethoxycoumarin and 7-ethoxyresorufin O-deethylase in the rat and effect of monoclonal antibodies. (1988) (4)
- Assay of the major (4-hydroxylated) metabolites of diphenylhydantoin in human urine (1975) (4)
- Subcellular Distribution of Styrene Oxide in Rat Liver (1984) (4)
- The Role of CYP2C8 and CYP2C9 Genotypes in Losartan‐Dependent Inhibition of Paclitaxel Metabolism in Human Liver Microsomes (2016) (4)
- Excretion of tiapamil in breast milk. (1988) (4)
- Profile of drug metabolizing enzymes in the nuclear and microsomal fractions from rat liver nodules and normal liver (2004) (4)
- INVERSE TEMPERATURE EFFECTS AND CONCENTRATION DEPENDENT APPARENT FIRST ORDER RATE CONSTANTS IN COMPLEX ION RADICAL REACTIONS (1981) (4)
- Seeking Improved Global Child Health: Progress Toward Millennium Development Goal 4 (2014) (4)
- Association of the cytochrome P450 1A2*1F polymorphism with clozapine response in schizophrenic patients (2007) (4)
- Influence of Simvastatin on the Thromboxane and Prostacyclin Pathways, In Vitro and In Vivo (2013) (4)
- PDE7B is involved in nandrolone decanoate hydrolysis in liver cytosol and its transcription is up-regulated by androgens in HepG2 (2014) (4)
- Hepatic oxygen consumption and cytochrome P450 activity in experimental faecal peritonitis. (1993) (3)
- Metabolism of a glutathione conjugate in human fetal and adult tissues. (1980) (3)
- Characterization of desmethylimipramine 2-hydroxylation in human foetal and adult liver microsomes. (2009) (3)
- Opiate-specific effects on mRNA and catalytic activity of a hepatic cytochrome P450 isozyme (1994) (3)
- WARFARIN DOSING ALGORITHM REFINEMENTS AFTER 7-9 DAYS OF THERAPY BASED ON PHARMACOGENETIC, PHARMACOKINETIC, CLINICAL, AND LABORATORY DATA (2010) (3)
- The Stabilizing Effect of Ion Occupancy on the Formation of Membrane Channels. (1981) (3)
- How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper (2022) (3)
- Determinants of drug disposition in infants (1996) (3)
- Tissue distribution and relative gene expression of UDP-glucuronosyltransferases ( 2 B 7 , 2 B 15 , 2 B 17 ) in the human fetus (2012) (2)
- The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile. (1981) (2)
- Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition (2018) (2)
- GABA AGONISTS. X-RAY CRYSTALLOGRAPHIC AND PROTON NMR SPECTROSCOPIC INVESTIGATIONS OF (3RS,4RS)-3-HYDROXYPIPERIDINE-4-CARBOXYLIC ACID (1981) (2)
- Carbamazepine in trigeminal neuralgia: clinical effects in relation to plasma-concentration. (1980) (2)
- Institutional profile: Karolinska Institutet. (2012) (1)
- Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity (2002) (1)
- Effect of Para Substituents on 31P Chemical Shifts of Alkyl Phenyl Phenylphosphonates. (1981) (1)
- Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function (2013) (1)
- BRIEF REPORT The Uridine Diphosphate Glucuronosyltransferase 2B15 D 85 Y and 2B17 Deletion Polymorphisms Predict the Glucuronidation Pattern of Androgens and Fat Mass in Men (2007) (1)
- Differential foetal development ofthe0-andN-demethylation ofcodeine anddextromethorphan inman (1991) (1)
- forecasting The largest prospective warfarin-treated cohort supports genetic (2012) (1)
- Axial Ligands of the Heme Iron in Soybean Leghemoglobin a as Investigated Using Resonance Raman Spectroscopy. (1981) (1)
- Glucuronidation of morphine and some drug oxidation reactions in liver microsomes from pregnant and non-pregnant rhesus monkeys. (1991) (1)
- Plasma concentration and plasma protein binding of diphenylhydantoin in the newborn infant. (1970) (1)
- Distribution and concordance of phenotypically and genotypically determined acetylation status on patients taking anti-tuberculosis drugs in Ethiopia (2006) (1)
- Biphasic kinetic profile for carbamazepine epoxide formation. (1977) (1)
- Anti-tubercular drug-induced hepatotoxicity in HIV-positive and negative patients (2006) (1)
- Combined effect of telmisartan and fluvastatin on arachidonic acid metabolism in human liver microsomes (2018) (1)
- Subject Index, Vol. 36, 1988 (1988) (1)
- 925 – KINETICS OF DIPHENYLHYDANTOIN (DPH) AND p-OH-DPH IN PLASMA AND URINE AFTER LOADING DOSES OF DPH IN CHILDREN (1977) (1)
- Caffeine Intake and the Risk of First-Trimester Spontaneous Abortion (2001) (1)
- Drug Metabolism at Various Ages — Young (1980) (1)
- Purification and Characterization of Maltose Binding Protein of Saccharomyces cerevisiae. (1981) (1)
- Abundance and distribution of hydroxymethylcytosine (5hmC) in human liver (2014) (0)
- Influence of genotype on warfarin dose requirements-a systematic review and meta-analysis (2020) (0)
- polymorphic serumpattern ofthe O-demethylated anddidemethylated metabolites inman (1989) (0)
- DMD049197 291..295 (2013) (0)
- Reply to ‘Multiple and Opposite Effects of Angiotensin II Receptor Blockers on the Bioavailability of Epoxyeicosatrienoic Acids’ (2017) (0)
- [Paracetamol and liver damage in a new light: are findings of tumors Gn mice and rats relevant for the clinical situation?]. (1985) (0)
- Challenges in Drug Therapy of Children in Africa (2015) (0)
- Interactions by tricyclic antidepressant drugs (TCA) with the human liver morphine-UDP-glucuronyl transferase and the opioid receptor binding in human brain (1990) (0)
- Valpromide is a poor inhibitor of the cytosolic epoxide hydrolase (2004) (0)
- The Prins Reaction of 2-Phenylbicyclo[2.2.1]hept-2-ene. (1981) (0)
- Vitamin D receptor rs2228570 polymorphism is associated with LH levels in men exposed to anabolic androgenic steroids (2018) (0)
- X-Ray Crystallographic Studies of 4,5,6,7-Tetrahydrobenzimidazole and Two Related Semirigid Histamine Analogues. (1981) (0)
- N-demethylation ofethylmorphine inpregnantandnon- pregnant women andinmen: an evaluation oftheeffects ofsex steroids (1992) (0)
- Quantitative assessment of cytochrome p450 mRNAs in liver needle biopsies. (1997) (0)
- Tribute to Folke Sjöqvist, a Pioneer in Clinical Pharmacology (2020) (0)
- 756 – GLUTATHIONE CONJUGATION OF PARACETAMOL BY HUMAN FETAL AND ADULT LIVER MICROSOMES (1978) (0)
- Endocrine and adrenergic pharmacological intervention in diseasesof the prostate: Pharmacological treatment of prostate diseases (2003) (0)
- Subject Index, Vol. 28, 1984 (1984) (0)
- Effects of angiotensin II receptor blockers on serum levels of epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids in patients admitted to a cardiovascular center (2021) (0)
- Early Impact of Severe Acute Respiratory Syndrome Coronavirus 2 on Pediatric Clinical Research: A Pan-European and Canadian Snapshot in Time (2021) (0)
- Correction to: Effects of angiotensin II receptor blockers on serum levels of epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids in patients admitted to a cardiovascular center (2021) (0)
- Metabolism of benzo(a)pyrene in the nuclear and microsomal fractions from rhesus monkey liver. (2009) (0)
- Contents, Vol. 28, 1984 (1984) (0)
- CYP3A and MDR1 (P-glycoprotein) gene expression levels along the human gastrointestinal tract (2005) (0)
- Problems Phenotyping of Drug Metabolism in Infants and Children : Potentials and Services (1999) (0)
- DECREASEDPLASMA PROTEINBINDING OF PHENYTOININPATIENTSON VALPROICACID (1979) (0)
- Contents, Vol. 36, 1988 (1984) (0)
- Variation i genexpression för cytokrom p-450 enzymer. Analys med reverse transcription (RT)-PCR i leverbiopsier. (1995) (0)
- [Introduction of genetic analysis can provide us with safer doping tests. Large variation in androgen turnover creates problems in current tests]. (2012) (0)
- THE PROSTATE IS AN IMPORTANT SYSTEMIC AND LOCO-REGIONAL ANDROGEN REGULATOR (2009) (0)
- KINETICS OFPLACENTALLY TRANSFERREDPHENYTOINAND ITS P-HYDROXYLATEDMETABOLITESINNEWBORN INFANTS (1979) (0)
- Correction to: Effects of angiotensin II receptor blockers on serum levels of epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids in patients admitted to a cardiovascular center (2021) (0)
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What Schools Are Affiliated With Anders Rane?
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