András F. Varró

Q: What Schools Are Affiliated With András F. Varró

András F. Varró is affiliated with the following schools: Heidelberg University, University of Liverpool, University of Szeged, University of Toronto

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András F. Varró

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Computer Science

András F. Varró's Degrees

PhD Computer Science Budapest University of Technology and Economics
Masters Computer Science Budapest University of Technology and Economics

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András F. Varró's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation (2011) (985)
Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer. (2000) (572)
Regional and tissue specific transcript signatures of ion channel genes in the non‐diseased human heart (2007) (478)
Restricting Excessive Cardiac Action Potential and QT Prolongation: A Vital Role for IKs in Human Ventricular Muscle (2005) (366)
Processing and proliferative effects of human progastrin in transgenic mice. (1996) (299)
A Mutation in the β3 Subunit of the Cardiac Sodium Channel Associated With Brugada ECG Phenotype (2009) (262)
Role of IKur in Controlling Action Potential Shape and Contractility in the Human Atrium: Influence of Chronic Atrial Fibrillation (2004) (259)
Gastrin deficiency results in altered gastric differentiation and decreased colonic proliferation in mice. (1997) (246)
The role of the delayed rectifier component IKs in dog ventricular muscle and Purkinje fibre repolarization (2000) (239)
Left-to-Right Atrial Inward Rectifier Potassium Current Gradients in Patients With Paroxysmal Versus Chronic Atrial Fibrillation (2010) (206)
Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium. (2005) (195)
Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis. (2000) (195)
Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts (2004) (174)
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts. (2010) (165)
Molecular basis of funny current (If) in normal and failing human heart. (2008) (164)
Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation. (1999) (162)
Cardiac ventricular repolarization reserve: a principle for understanding drug‐related proarrhythmic risk (2011) (157)
Asymmetrical distribution of ion channels in canine and human left-ventricular wall: epicardium versus midmyocardium (2005) (145)
An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes (1993) (140)
Interaction of different potassium channels in cardiac repolarization in dog ventricular preparations: role of repolarization reserve (2002) (137)
Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts. (2006) (133)
The slow component of the delayed rectifier potassium current in undiseased human ventricular myocytes. (2001) (132)
Ionic currents and action potentials in rabbit, rat, and guinea pig ventricular myocytes (1993) (129)
Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy. (2013) (128)
Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs (2013) (126)
Pharmacological block of the slow component of the outward delayed rectifier current (IKs) fails to lengthen rabbit ventricular muscle QTc and action potential duration (2001) (123)
Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation. (2011) (123)
Molecular basis of species-specific expression of repolarizing K+ currents in the heart. (2003) (120)
Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16 (2013) (119)
Effects of SEA0400 and KB-R7943 on Na+/Ca2+ exchange current and L-type Ca2+ current in canine ventricular cardiomyocytes (2005) (118)
Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone (2001) (112)
Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig (2008) (112)
Pathology‐specific effects of the IKur/Ito/IK,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation (2008) (110)
Delayed rectifier potassium current in undiseased human ventricular myocytes. (1998) (108)
Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen. (2000) (107)
Combined pharmacological block of IKr and IKs increases short‐term QT interval variability and provokes torsades de pointes (2007) (106)
A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis. (2011) (105)
Effects of endothelin-1 on calcium and potassium currents in undiseased human ventricular myocytes (2000) (103)
Estimate of net calcium fluxes and sarcoplasmic reticulum calcium content during systole in rat ventricular myocytes. (1995) (102)
Usefulness of short-term variability of QT intervals as a predictor for electrical remodeling and proarrhythmia in patients with nonischemic heart failure. (2010) (101)
Mutations of RegIalpha are associated with enterochromaffin-like cell tumor development in patients with hypergastrinemia. (1999) (99)
Contributions of HERG K+ current to repolarization of the human ventricular action potential. (2008) (98)
Diabetes mellitus attenuates the repolarization reserve in mammalian heart. (2007) (97)
Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block (2019) (96)
Transcriptomal analysis of failing and nonfailing human hearts. (2003) (96)
Endocardial versus epicardial differences in L-type calcium current in canine ventricular myocytes studied by action potential voltage clamp. (2003) (96)
Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization? (2009) (94)
Selective inhibition of sodium–calcium exchanger by SEA‐0400 decreases early and delayed afterdepolarization in canine heart (2004) (93)
Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts (2009) (93)
Peroxynitrite-induced alpha-actinin nitration and contractile alterations in isolated human myocardial cells. (2005) (92)
Slow Delayed Rectifier Potassium Current (IKs) and the Repolarization Reserve (2007) (89)
Pharmacological Inhibition of Na/Ca Exchange Results in Increased Cellular Ca2 Load Attributable to the Predominance of Forward Mode Block (2008) (87)
Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk. (2010) (85)
Comparison of the chronic and acute effects of amiodarone on the calcium and potassium currents in rabbit isolated cardiac myocytes (1996) (77)
Systems Approach to Understanding Electromechanical Activity in the Human Heart: A National Heart, Lung, and Blood Institute Workshop Summary (2008) (75)
Reorganized PKA-AKAP associations in the failing human heart. (2012) (74)
Proteome-wide protein concentrations in the human heart. (2010) (74)
Glycine-extended gastrin synergizes with gastrin 17 to stimulate acid secretion in gastrin-deficient mice. (2000) (74)
Frequency-Dependent Effects of Several Class I Antiarrhythmic Drugs on &OV0312;max of Action Potential Upstroke in Canine Cardiac Purkinje Fibers (1985) (72)
Mice overexpressing progastrin are predisposed for developing aberrant colonic crypt foci in response to AOM. (2000) (72)
Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications (2018) (71)
Effect of Antiarrhythmic Drugs on the Cycle Length-Dependent Action Potential Duration in Dog Purkinje and Ventricular Muscle Fibers (1986) (70)
Unique Cardiac Purkinje Fiber Transient Outward Current &bgr;-Subunit Composition: A Potential Molecular Link to Idiopathic Ventricular Fibrillation (2013) (68)
Heterogeneous Connexin43 distribution in heart failure is associated with dispersed conduction and enhanced susceptibility to ventricular arrhythmias (2010) (67)
Comparison of the cellular electrophysiological characteristics of canine left ventricular epicardium, M cells, endocardium and Purkinje fibres. (1998) (67)
Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes. (2004) (66)
ORM‐10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart (2013) (65)
Potassium currents in isolated human atrial and ventricular cardiocytes. (1993) (65)
Complex electrophysiological remodeling in postinfarction ischemic heart failure (2018) (64)
Gene expression profiling of human cardiac potassium and sodium channels. (2006) (64)
Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): Standardised Reporting for Model Reproducibility, Interoperability, and Data Sharing (2011) (63)
Use-dependent effects of amiodarone on Vmax in cardiac Purkinje and ventricular muscle fibers. (1985) (61)
Calpain-1-sensitive myofibrillar proteins of the human myocardium (2005) (60)
Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart (2014) (59)
Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy (2017) (59)
The secretory kinetics of the G cell in omeprazole-treated rats. (1991) (59)
Application of neural networks in structure–activity relationships (1999) (58)
Role of KATP Channels in the Maintenance of Ventricular Fibrillation in Cardiomyopathic Human Hearts (2011) (58)
A new severe acute necrotizing pancreatitis model induced by l-ornithine in rats (2008) (55)
ATP-sensitive potassium channel modulators: both pinacidil and glibenclamide produce antiarrhythmic activity during acute myocardial infarction in conscious rats. (1996) (54)
Sodium calcium exchange as a target for antiarrhythmic therapy. (2006) (54)
Reverse rate-dependent changes are determined by baseline action potential duration in mammalian and human ventricular preparations (2010) (54)
Reverse rate dependency is an intrinsic property of canine cardiac preparations. (2009) (54)
Preconditioning Effects of Levosimendan in a Rabbit Cardiac Ischemia-Reperfusion Model (2006) (54)
Levosimendan interacts with potassium channel blockers in human saphenous veins. (2004) (53)
Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases. (2009) (53)
Monoamine oxidases are novel sources of cardiovascular oxidative stress in experimental diabetes. (2015) (53)
Human Electrophysiological and Pharmacological Properties of XEN-D0101: A Novel Atrial-Selective Kv1.5/IKur Inhibitor (2013) (50)
Effects of thymol on calcium and potassium currents in canine and human ventricular cardiomyocytes (2002) (50)
Possible mechanisms of sudden cardiac death in top athletes: a basic cardiac electrophysiological point of view (2010) (49)
Rate and concentration‐dependent effects of UK‐68,798, a potent new class III antiarrhythmic, on canine Purkinje fibre action potential duration and Vmax (1991) (48)
Electrophysiological effects of ivabradine in dog and human cardiac preparations: potential antiarrhythmic actions. (2011) (48)
Activation of the Poly(ADP-Ribose) Polymerase Pathway in Human Heart Failure (2006) (48)
C-type natriuretic peptide hyperpolarizes and relaxes human penile resistance arteries. (2005) (46)
Cardiac Transmembrane Ion Channels and Action Potentials: Cellular Physiology and Arrhythmogenic Behavior. (2020) (46)
Role of slow delayed rectifier K+‐current in QT prolongation in the alloxan‐induced diabetic rabbit heart (2008) (44)
Protein kinase C mediates the inhibitory effect of substance P on HCO3- secretion from guinea pig pancreatic ducts. (2005) (44)
Deranged sodium to sudden death (2015) (44)
The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments (2016) (44)
Unique Cardiac Purkinje Fiber Transient Outward Current β-Subunit CompositionNovelty and Significance (2013) (43)
Combined Na+/Ca2+ Exchanger and L-Type Calcium Channel Block as a Potential Strategy to Suppress Arrhythmias and Maintain Ventricular Function (2013) (42)
Theoretical possibilities for the development of novel antiarrhythmic drugs. (2004) (42)
A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant‐negative mutation of the KCNE1 gene (2016) (41)
Selective Na+/Ca2+ exchanger inhibition prevents Ca2+ overload‐induced triggered arrhythmias (2014) (41)
The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study (2017) (41)
Reopening of L-type calcium channels in human ventricular myocytes during applied epicardial action potentials. (2004) (40)
Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop (2015) (40)
Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes (2015) (40)
5,7,8-Trimethyl-benzopyran and 5,7,8-trimethyl-1,4-benzoxazine aminoamide derivatives as novel antiarrhythmics against ischemia-reperfusion injury. (2009) (39)
Classification of positive inotropic actions based on electrophysiologic characteristics: where should calcium sensitizers be placed? (1995) (39)
Differential Electrophysiologic Effects of Chronically Administered Amiodarone on Canine Purkinje Fibers versus Ventricular Muscle (1996) (39)
Effect of Levosimendan and Milrinone on Regional Myocardial Ischemia/Reperfusion-Induced Arrhythmias in Dogs (2006) (39)
Novel blockers of hyperpolarization‐activated current with isoform selectivity in recombinant cells and native tissue (2012) (38)
COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo. (2005) (38)
The role of the Na+/Ca2+ exchanger, INa and ICaL in the genesis of dofetilide‐induced torsades de pointes in isolated, AV‐blocked rabbit hearts (2009) (37)
Role of I Kur in Controlling Action Potential Shape and Contractility in the Human Atrium Influence of Chronic Atrial Fibrillation (2004) (36)
Na+/Ca2+ exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart (2008) (36)
Gastrin biosynthesis in the antrum of patients with pernicious anemia. (1997) (36)
In vitro cardiac models of dog Purkinje fibre triggered and spontaneous electrical activity: effects of nicorandil (1990) (35)
Effect of antiarrhythmic drugs on the premature action potential duration in canine cardiac Purkinje fibers. (1985) (35)
Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations. (2011) (34)
Self‐augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency (2009) (33)
The Na+/Ca2+ exchange blocker SEA0400 fails to enhance cytosolic Ca2+ transient and contractility in canine ventricular cardiomyocytes. (2008) (33)
Sotalol and Mexiletine: Combination of Rate‐Dependent Electrophysiological Effects (1990) (32)
Relevance of anaesthesia for dofetilide‐induced torsades de pointes in α1‐adrenoceptor‐stimulated rabbits (2008) (32)
Effects of Chelidonium majus extracts and major alkaloids on hERG potassium channels and on dog cardiac action potential - a safety approach. (2015) (31)
Effect of partial blockade of the Na(+)/Ca(2+)-exchanger on Ca(2+) handling in isolated rat ventricular myocytes. (2007) (31)
Cholecystokinin and Gastrin Forms in the Nervous System (1985) (30)
Effect of disopyramide on potassium currents in rabbit ventricular myocytes (1998) (30)
Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition (2016) (30)
Increased Short-Term Variability of the QT Interval in Professional Soccer Players: Possible Implications for Arrhythmia Prediction (2011) (30)
New experimental method to study acid/base transporters and their regulation in lacrimal gland ductal epithelia. (2007) (29)
[Ca2+]i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium (2013) (29)
Evaluation of Possible Proarrhythmic Potency: Comparison of the Effect of Dofetilide, Cisapride, Sotalol, Terfenadine, and Verapamil on hERG and Native IKr Currents and on Cardiac Action Potential (2019) (29)
Action potential duration and force-frequency relationship in isolated rabbit, guinea pig and rat cardiac muscle (2004) (29)
Modulation of the cleavage of the gastrin precursor by prohormone phosphorylation. (1998) (29)
Rate-dependent electrophysiological effects of OPC-8212: comparison to sotalol. (1989) (29)
Altered expression of genes for Kir ion channels in dilated cardiomyopathy. (2013) (29)
Analysis of the contribution of Ito to repolarization in canine ventricular myocardium (2011) (28)
Rabbit models as tools for preclinical cardiac electrophysiological safety testing: Importance of repolarization reserve. (2016) (27)
Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation (2014) (26)
Caffeine‐induced decreases in the inward rectifier potassium and the inward calcium currents in rat ventricular myocytes (1993) (25)
Suppression of Erythromycin‐induced Early Afterdepolarizations and Torsade de Pointes Ventricular Tachycardia by Mexiletine (1998) (25)
Involvement of Large‐Conductance Ca2+‐Activated K+ Channels in both Nitric Oxide and Endothelium‐Derived Hyperpolarization‐Type Relaxation in Human Penile Small Arteries (2013) (25)
Comparison of the Effect of Class IA Antiarrhythmic Drugs on Transmembrane Potassium Currents in Rabbit Ventricular Myocytes (2003) (25)
Potential therapeutic effects of Na+/Ca2+ exchanger inhibition in cardiac diseases. (2009) (25)
Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities (2020) (25)
Comparison of the efficiency of Na+/Ca2+ exchanger or Na+/H+ exchanger inhibition and their combination in reducing coronary reperfusion-induced arrhythmias. (2015) (24)
Acute effects of cigarette smoking on the QT interval in healthy smokers. (2003) (24)
The impact of single cell voltage clamp on the understanding of the cardiac ventricular action potential. (1992) (24)
The cellular electrophysiological effects of tedisamil in human atrial and ventricular fibers. (1996) (24)
Academia Europaea Position Paper on Translational Medicine: The Cycle Model for Translating Scientific Results into Community Benefits (2020) (23)
The combined electrophysiological effects of lignocaine and sotalol in canine isolated cardiac Purkinje fibres are rate‐dependent (1990) (23)
Synthesis and biological evaluation of benzopyran analogues bearing class III antiarrhythmic pharmacophores. (2006) (22)
Effect of the antifibrillatory compound tedisamil (KC-8857) on transmembrane currents in mammalian ventricular myocytes. (2004) (22)
Sarcolemmal Ca(2+)-entry through L-type Ca(2+) channels controls the profile of Ca(2+)-activated Cl(-) current in canine ventricular myocytes. (2016) (21)
Herpesvirus-Mediated Delivery of a Genetically Encoded Fluorescent Ca2+ Sensor to Canine Cardiomyocytes (2009) (21)
Importance of extracardiac alpha1-adrenoceptor stimulation in assisting dofetilide to induce torsade de pointes in rabbit hearts. (2006) (21)
Increased tissue concentrations of the gastrin precursor in patients treated with omeprazole (1992) (21)
The potential impact of new generation transgenic methods on creating rabbit models of cardiac diseases. (2016) (21)
Regional Ion Channel Gene Expression Heterogeneity and Ventricular Fibrillation Dynamics in Human Hearts (2014) (20)
Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure (2017) (20)
NEP inhibitors enhance C-type natriuretic peptide-induced relaxation in porcine isolated coronary artery. (2005) (20)
Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk (2004) (20)
Voltage-clamp characteristics of ventricular myocytes in rabbit. (1991) (19)
Frequency-dependent Cardiac Electrophysiologic Effects of Tedisamil: Comparison With Quinidine and Sotalol (1997) (19)
Cardiac electrophysiological effects of levosimendan, a new calcium sensitizer. (1996) (19)
Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine Helicobacter infection (2007) (19)
Efficacy of selective NCX inhibition by ORM-10103 during simulated ischemia/reperfusion. (2014) (19)
Low penetrance, subclinical congenital LQTS: concealed LQTS or silent LQTS? (2006) (19)
Vitamin E models. Can the anti-oxidant and pro-oxidant dichotomy of α-tocopherol be related to ionic ring closing and radical ring opening redox reactions? (2003) (18)
Ionic currents in ventricular myocytes isolated from the heart of a patient with idiopathic cardiomyopathy. (1992) (18)
Absolute beat‐to‐beat variability and instability parameters of ECG intervals: biomarkers for predicting ischaemia‐induced ventricular fibrillation (2014) (18)
Late sodium current in human, canine and guinea pig ventricular myocardium. (2020) (18)
Short-term beat-to-beat variability of the QT interval is increased and correlates with parameters of left ventricular hypertrophy in patients with hypertrophic cardiomyopathy. (2015) (18)
L-364,373 fails to activate the slow delayed rectifier K+ current in canine ventricular cardiomyocytes (2006) (18)
Increased Short-Term Beat-to-Beat QT Interval Variability in Patients with Impaired Glucose Tolerance (2017) (18)
Development of pharmacophores for inhibitors of the rapid component of the cardiac delayed rectifier potassium current (1998) (18)
Selective pharmacological inhibition of the pacemaker channel isoforms (HCN1-4) as new possible therapeutical targets. (2011) (17)
Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women (2017) (17)
Novel antiarrhythmic compounds with combined class IB and class III mode of action. (2004) (17)
Vitamin E models. Shortened sidechain models of α, β, γ and δ tocopherol and tocotrienol—a density functional study (2003) (17)
The effects of amiodarone on repolarization and refractoriness of cardiac fibers. (1988) (17)
Prolonged antispasmodic effect in isolated radial artery graft and pronounced platelet inhibition induced by the inodilator drug, levosimendan. (2012) (16)
Age-related regulation and region-specific distribution of ion channel subunits promoting atrial fibrillation in human left and right atria. (2019) (16)
The electrophysiological effect of cannabidiol on hERG current and in guinea-pig and rabbit cardiac preparations (2020) (16)
Exploration of the Four-Dimensional-Conformational Potential Energy Hypersurface of N-Acetyl-L-aspartic Acid N'-Methylamide with Its Internally Hydrogen Bonded Side-Chain Orientation (2002) (16)
Modulation of posttranslational processing of gastrin precursor in dogs. (1990) (16)
Antiarrhythmic agents: Current status and perspectives (1997) (16)
Biomarkers and endogenous determinants of dofetilide‐induced torsades de pointes in α1‐adrenoceptor‐stimulated, anaesthetized rabbits (2010) (16)
Modulation of gastrin processing by vesicular monoamine transporter type 1 (VMAT1) in rat gastrin cells (1999) (16)
Atrial remodeling and novel pharmacological strategies for antiarrhythmic therapy in atrial fibrillation. (2011) (15)
Effect of sotalol on transmembrane ionic currents responsible for repolarization in cardiac ventricular myocytes from rabbit and guinea pig. (1991) (15)
Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury. (2019) (15)
Effects of Antiarrhythmic Drugs on Premature Action Potential Duration in Canine Ventricular Muscle Fibers (1987) (15)
Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve (2012) (15)
Intracellular calcium and electrical restitution in mammalian cardiac cells. (1998) (14)
Abstract 1520: Molecular Basis of Repolarization Reserve Differences between Dogs and Man (2008) (14)
Role of Ca²+-sensitive K+ currents in controlling ventricular repolarization: possible implications for future antiarrhytmic drug therapy. (2011) (14)
Beat-to-beat variability of cardiac action potential duration: underlying mechanism and clinical implications. (2017) (14)
Conformational effects of one glycine residue on the other glycine residues in the Ac-Gly-Gly-Gly-NHMe tripeptide motif: an ab initio exploratory study (2002) (13)
Block of Na(+)/Ca(2+) exchanger by SEA0400 in human right atrial preparations from patients in sinus rhythm and in atrial fibrillation. (2016) (13)
Density functional molecular computations on protonated serotonin in the gas phase and various solvent media (2002) (13)
Ionic basis for OPC-8212-induced increase in action potential duration in isolated rabbit, guinea pi (1993) (13)
Increased Short-Term Beat-To-Beat Variability of QT Interval in Patients with Acromegaly (2015) (13)
Antiarrhythmic and electrophysiological effects of GYKI-16638, a novel N-(phenoxyalkyl)-N-phenylalkylamine, in rabbits. (2000) (13)
Electrical restitution in rat ventricular muscle. (1996) (13)
A novel 'splice site' HCN4 Gene mutation, c.1737+1 G>T, causes familial bradycardia, reduced heart rate response, impaired chronotropic competence and increased short-term heart rate variability. (2017) (13)
Multiple cellular electrophysiological effects of azimilide in canine cardiac preparations. (2003) (13)
Synthesis and antiarrhythmic activity of N-aryl alkylenediamines (1987) (13)
Transgenic LQT2, LQT5, and LQT2‐5 rabbit models with decreased repolarisation reserve for prediction of drug‐induced ventricular arrhythmias (2020) (12)
Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion (2020) (12)
Vitamin E models. Conformational analysis and stereochemistry of tetralin, chroman, thiochroman and selenochroman (2002) (12)
Effect of herpesvirus infection on pancreatic duct cell secretion. (2005) (12)
Vasorelaxing effect of levosimendan against 5‐hydroxytryptamine‐induced contractions in isolated human conduit bypass grafts (2006) (11)
SEA0400 fails to alter the magnitude of intracellular Ca2+ transients and contractions in Langendorff-perfused guinea pig heart (2008) (11)
Role of the delayed rectifier component I(Ks) in cardiac repolarization. (2001) (11)
Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM‐10962 on canine ventricular myocytes (2018) (11)
Electrophysiological effects of EGIS-7229, a new antiarrhythmic agent, in isolated mammalian and human cardiac tissues (1997) (11)
Three distinct components of the negative inotropic action of lidocaine in dog Purkinje fiber. (1996) (11)
3,8-diazabicyclo--[3.2.1]-octane derivatives as analogues of ambasilide, a Class III antiarrhythmic agent. (2001) (11)
Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue (2020) (11)
How reliable could economic Hartree–Fock computations be in studying large, folded peptides? A comparative HF and DFT case study on N- and C-protected aspartic acid (2002) (10)
Frontiers in Medicinal Chemistry (2016) (10)
Density functional molecular study on the full conformational space of the S-4-(2-hydroxypropoxy)carbazol fragment of carvedilol (1-(9H-carbazol-4-yloxy)-3[2-(2-methoxyphenoxy)ethylamino]-2-propanol) in vacuum and in different solvent media (2002) (10)
Long-term endurance training-induced cardiac adaptation in new rabbit and dog animal models of the human athlete's heart. (2018) (10)
Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women (2017) (10)
A comparative conformational analysis of selected central nervous system stimulants (2003) (10)
Biseko colloidal solution diminishes the vasoreactivity of human isolated radial arteries. (2009) (10)
Molecular Study on the Enantiomeric Relationships of Carvedilol Fragment A, 4-(2-Hydroxypropoxy)carbazol, along with Selected Analogues (2003) (10)
Effects of Propranolol on Premature Action Potentials in Canine Purkinje and Ventricular Muscle (1990) (10)
Impact of neonatal treatment with cardioactive glycosides (digoxin, ouabain) on receptor binding capacity, blood level and cardiac function in the adult rat. Extension of the imprinting theory. (1983) (10)
Ionic basis for OPC-8212-induced increase in action potential duration in isolated rabbit, guinea pig and human ventricular myocytes. (1992) (10)
The Cardiac Pacemaker Story—Fundamental Role of the Na+/Ca2+ Exchanger in Spontaneous Automaticity (2020) (9)
An ab initio and DFT conformational analysis of unsubstituted and ω-substituted ethyl-benzene: (Ph–CH2–CH2–Z; Z=–H, –F, –NH3+, –CH3) (2002) (9)
Antiarrhythmic effect of acute and chronic amiodarone treatment in conscious rats (1986) (9)
Effect of sotalol on transmembrane ionic currents responsible for repolarization in cardiac ventricular myocytes from rabbit and guinea pig (1991) (9)
Discrimination between constitutive secretion and basal secretion from the regulated secretory pathway in GH3 cells. (1996) (9)
Analysis of the electrophysiological effects of ambasilide, a new antiarrhythmic agent, in canine isolated ventricular muscle and purkinje fibers. (2000) (9)
Assessment of Efficacy of Proarrhythmia Biomarkers in Isolated Rabbit Hearts With Attenuated Repolarization Reserve (2014) (9)
Combined inhibition of key potassium currents has different effects on cardiac repolarization reserve and arrhythmia susceptibility in dogs and rabbits. (2015) (9)
Inter-Species Differences in the Response of Sinus Node Cellular Pacemaking to Changes of Extracellular Calcium (2019) (9)
Vitamin E models (2002) (9)
Antiarrhythmic potential of drugs targeting the cardiac ryanodine receptor Ca2+ release channel: case study of dantrolene. (2014) (8)
Gastrin cell responses to acidification of the achlorhydric rat stomach. (1993) (8)
Modulation of the effects of sotalol on Purkinje strand electromechanical characteristics. (1989) (8)
Electrical Restitution and Its Modifications by Antiarrhythmic Drugs in Undiseased Human Ventricular Muscle (2020) (8)
SLC26 transporters and the inhibitory control of pancreatic ductal bicarbonate secretion. (2006) (8)
Cardiac sarcolemmal ion channels and transporters as possible targets for antiarrhythmic and positive inotropic drugs: strategies of the past--perspectives of the future. (2004) (8)
Mechanism of reverse rate-dependent action of cardioactive agents. (2011) (8)
Novel experimental results in human cardiac electrophysiology: measurement of the Purkinje fibre action potential from the undiseased human heart. (2015) (8)
New in vitro model for proarrhythmia safety screening: IKs inhibition potentiates the QTc prolonging effect of IKr inhibitors in isolated guinea pig hearts. (2016) (8)
Identification and functional characterisation of a novel KCNJ2 mutation, Val302del, causing Andersen-Tawil syndrome. (2015) (8)
Potassium channels sensitive to combination of charybdotoxin and apamin regulate the tone of diabetic isolated canine coronary arteries (2008) (8)
Alternative promoter usage and splicing of the human SCN5A gene contribute to transcript heterogeneity. (2010) (8)
An assessment of the chiral environment created by adjacent d- and l-alanyl residues on a glycine unit within the tripeptide N-Ac-Ala-Gly-Ala-NHMe: an ab initio exploratory study (2003) (8)
Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete’s heart model (2020) (8)
Cellular properties of C-terminal KCNH2 long QT syndrome mutations: description and divergence from clinical phenotypes. (2008) (8)
Arrhythmogenic Remodeling in the Failing Heart (2021) (8)
Differences in the Effects of d- and dl-Sotalol on Isolated Human Ventricular Muscle: Electromechanical Activity After Beta-Adrenoceptor Stimulation (1996) (7)
Effect of Altered Repolarization Course Induced by Antiarrhythmic Drugs and Constant Current Pulses on Duration of Premature Action Potentials in Canine Cardiac Purkinje Fibers (1989) (7)
L-364,373 (R-L3) enantiomers have opposite modulating effects on IKs in mammalian ventricular myocytes. (2013) (7)
Low 4-aminopyridine concentration-induced contraction is mediated by neuronal noradrenaline in canine saphenous vein. (2002) (7)
Comparison of the effects of IK,ACh, IKr, and INa block in conscious dogs with atrial fibrillation and on action potentials in remodeled atrial trabeculae. (2018) (7)
EGIS-7229, the new combined class III antiarrhythmic agent: lack of EAD inducing effect. (1999) (7)
Cellular electrophysiological effect of terikalant in the dog heart. (2005) (7)
Discovery and characterization of ORM-11372, a unique and positively inotropic sodium-calcium exchanger/inhibitor. (2020) (6)
Canine Myocytes Represent a Good Model for Human Ventricular Cells Regarding Their Electrophysiological Properties (2021) (6)
Blockade of sodium‑calcium exchanger via ORM-10962 attenuates cardiac alternans (2020) (6)
The cellular electrophysiologic effect of a new amiodarone like antiarrhythmic drug GYKI 16638 in undiseased human ventricular muscle: comparison with sotalol and mexiletine. (2002) (6)
Electrophysiological effects of EGIS-7229, a new antiarrhythmic agent, in isolated guinea pig papillary muscle. (1997) (6)
Drug-induced changes in action potential duration are proportional to action potential duration in rat ventricular myocardium. (2010) (6)
Predicting the conformational preferences of N-acetyl-4-hydroxy-l-proline-N′-methylamide from the proline residue (2003) (6)
Long-term pretreatment with desethylamiodarone (DEA) or amiodarone (AMIO) protects against coronary artery occlusion induced ventricular arrhythmias in conscious rats. (2015) (6)
Electrical restitution in diseased human ventricular myocardium. (1996) (6)
P6-2: Role of the slowly inactivating transient outward potassium current in cardiac repolarization (2006) (6)
The investigation of the cellular electrophysiological and antiarrhythmic effects of a novel selective sodium-calcium exchanger inhibitor, GYKB-6635, in canine and guinea-pig hearts. (2016) (6)
Phosphorylation of gastrin-related peptides: Physiological casein kinase like enzyme in Golgi membranes from bovine adrenal chromaffin cells and GH3 cells (1997) (6)
Phosphorylation of human preprogastrin 93-101 by a Golgi membrane kinase from rat mammary gland. (1994) (6)
Effects of veratridine on Na and Ca currents in frog skeletal muscle. (1994) (6)
Conformational dependence of the intrinsic acidity of the aspartic acid residue sidechain in N-acetyl-L-aspartic acid-N′-methylamide (2003) (5)
Effect of GLG-V-13, a class III antiarrhythmic agent, on potassium currents in rabbit ventricular myocytes. (2000) (5)
Isolation of human ventricular and atrial cardiomyocytes: technical note. (1993) (5)
N-acetyl-L-aspartic acid-N'-methylamide with side-chain orientation capable of external hydrogen bonding (2002) (5)
Pharmacological Modification of the Dispersion of Repolarization in the Heart: Importance of the M Cells (1999) (5)
Comparison of the Electromechanical Effects of Vesnarinone and Amrinone in Isolated Dog Purkinje Strands and Ventricular Trabeculae (1996) (5)
Gas phase conformational basicity of carvedilol Fragment B, 2(S)-1-(ethylamonium)propane-2-ol: An ab initio study on a protonophoretic of oxidative phosphorylation uncoupling (2003) (5)
Role of calcium-activated potassium channels in the regulation of basal and agonist-elevated tones in isolated conduit arteries. Short communication. (2004) (4)
The novel inodilator ORM-3819 relaxes isolated porcine coronary arteries: role of voltage-gated potassium channels activation. (2019) (4)
Synthesis and anti-arrhythmic activity of aminoguanidine derivatives (1993) (4)
Late Na+ Current Is [Ca2+]i-Dependent in Canine Ventricular Myocytes (2021) (4)
Mexiletine-like cellular electrophysiological effects of GS967 in canine ventricular myocardium (2021) (4)
New antiarrhythmic agents: a conceptually novel approach (2000) (4)
Antiarrhythmic effect of desethylamiodarone in conscious rats (1987) (4)
Age-Related Changes in Electromechanical Properties of Canine Ventricular Muscle: Effect of Ouabain (1989) (3)
NEW ANTIARRHYTHMIC AGENT WITH POSITIVE CARDIAC ACTIONS (GYKI-38 233) (1986) (3)
Action-potential duration and contractility in canine cardiac tissues: action of inotropic drugs. (1998) (3)
Na +/Ca 2+ exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart (British Journal of Pharmacology (2008) 154, (93-104) DOI: 10.1038/bjp.2008.83) (2008) (3)
[Complementary therapies--based on the principles of evidence-based medicine. Position statement of the Medical Sciences Section of the Hungarian Academy of Sciences]. (2011) (3)
Tedisamil is a potent blocker of ATP-sensitive potassium channels in cardiac muscle (1997) (3)
Tedisamil is a potent blocker of ATP-sensitive potassium channels in cardiac muscle (1997) (3)
Examination of the Changes in Calcium Homeostasis in the Delayed Antiarrhythmic Effect of Sodium Nitrite (2019) (3)
Active and passive electrical properties of isolated canine cardiac Purkinje fibers under conditions simulating ischaemia: effect of diltiazem. (1992) (3)
132 Peroxinitrite induced mechanical alterations of the actin‐myosin interaction in isolated human myocardial cells (2003) (3)
P6-18: Estimation of the proarrhythmic risk by short term variability of QT-interval and/or action potential duration in dog (2006) (3)
The effect of levosimendan during long-term amiodarone treatment in dogs. (2006) (3)
Use-dependent action of antiarrhythmic drugs in frog skeletal muscle and canine cardiac Purkinje fiber. (1990) (3)
Long-Term Endurance Exercise Training Alters Repolarization in a New Rabbit Athlete’s Heart Model (2022) (3)
Different electrophysiological effects of the levo- and dextro-rotatory isomers of mexiletine in isolated rabbit cardiac muscle. (2017) (3)
Pancreatic amylase- and protein-concentrations associated with thioacetamide-induced cirrhosis of the liver in rats. (1978) (3)
278LQT5 transgenic rabbits are characterized by increased repolarization instability and arrhythmia susceptibility (2014) (3)
The influence of feeding and fasting on the phosphorylation of gastrin-related peptides in the pyloric antral mucosa of the rat (1990) (3)
Implication of frequency-dependent protocols in antiarrhythmic and proarrhythmic drug testing. (2019) (3)
Quantification of the surface expression of ionchannel and gap junction proteins on cardiac myocytes with confocal microscopy (2006) (2)
Cardioprotection and arrhythmias, Part I. (2015) (2)
What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart (2012) (2)
Properties of the transient outward, ultra-rapid delayed rectifier and acetylcholine-sensitive potassium currents in isolated atrial myocytes from dogs: sinus rhythm and tachypaced model of permanent atrial fibrillation (2011) (2)
Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil Syndrome patient. (2020) (2)
Role of the dysfunctional ryanodine receptor - Na(+)-Ca(2+)exchanger axis in progression of cardiovascular diseases: What we can learn from pharmacological studies? (2016) (2)
Electrophysiological Effects of GYKI‐23 107, a New Antiarrhythmic Compound, in Isolated Rabbit and Canine Cardiac Preparations (1988) (2)
Electrophysiologic effects of FPL 13210 on canine Purkinje fiber action potential duration and Vmax comparison to disopyramide (1991) (2)
[Pathogenesis and clinical significance of atrial fibrillation]. (2003) (2)
Excessive Cardiac Action Potential and QT Prolongation : A Vital Role for IKs (2005) (2)
Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity (2020) (2)
Inhibition of thrombin-induced platelet aggregation by levosimendan is modified by small changes in albumin concentration in vitro (2013) (2)
Data-Driven Identification of Stochastic Model Parameters and State Variables: Application to the Study of Cardiac Beat-to-Beat Variability (2020) (2)
Nonlinear relationship between V+max and h infinity in frog skeletal muscle. (1992) (2)
Use-dependent blockade of sodium channels induced by bencyclane in frog skeletal muscle and canine cardiac Purkinje fiber. (1987) (2)
Repolarization-related ECG parameters do not predict the proarrhythmic activity of dofetilide (2007) (2)
Correction: Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition (2018) (2)
Effect of inter-subject variability in determining response to IKr block in human ventricular myocytes (2014) (2)
Personalised health education against health damage of COVID-19 epidemic in the elderly Hungarian population (PROACTIVE-19): protocol of an adaptive randomised controlled clinical trial (2020) (2)
Frequency-dependent and independent effects of tetrodotoxin on Vmax in cardiac fibers. (1989) (2)
Antiarrhythmic and cardiac electrophysiological effects of SZV-270, a novel compound with combined Class I/B and Class III effects, in rabbits and dogs. (2020) (2)
Molecular computations on lipids: a numbering system for phospholipids and triglyceride (2002) (2)
Docosahexaenoic acid normalizes QT interval in long QT type 2 transgenic rabbit models in a genotype-specific fashion. (2021) (2)
Hyperventilation assists proarrhythmia development during delayed repolarization in clofilium-treated, anaesthetized, mechanically ventilated rabbits. (2016) (2)
The electrophysiological effects of cannabidiol on action potentials and transmembrane potassium currents in rabbit and dog cardiac ventricular preparations (2021) (2)
Abstract 1369: Gender-related Differences In Non-diseased Human Epicardial-endocardial Ion-channel Expression Heterogeneity (2007) (1)
DIFERENTIAL EFFECTS OF BILE ACIDS ON PANCREATIC DUCTAL BICARBONATE SECRETION (2007) (1)
Application of ventricular tachyarrhythmia definitions of the updated Lambeth Conventions provides incompatibility with earlier results, masks antifibrillatory activity and reduces inter-observer agreement. (2019) (1)
The role of the transient outward current in action potential repolarization: A simulation study (2010) (1)
Different effect of amiodarone and dofetilide on the dispersion of repolarization between well coupled ventricular and Purkinje fibers. (2020) (1)
Expression Quantitative Trait Locus (eQTL) analysis in human heart for elucidation of causal genes at loci identified in genome-wide association studies (2013) (1)
The development of L-type Ca2+ current mediated alternans does not depend on the restitution slope in canine ventricular myocardium (2021) (1)
Concentration- and rate-dependent electrophysiological effects of restacorin on isolated canine purkinje fibres (1990) (1)
Nonlinear Relationship Between V+ax and ftM in Prog Skeletal Muscle (1992) (1)
Recovery of V(max) and of action potential duration in canine cardiac purkinje fibers (1984) (1)
Calcium Activated Chloride Current in Mammalian Ventricular Myocytes (2017) (1)
Athletic heart: The possible role of impaired repolarization reserve in development of sudden cardiac death (2012) (1)
Characterisation of familial idiopathic ventricular fibrillation linked to DPP6 (2013) (1)
Corrigendum: The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study (2017) (1)
Biphasic effect of tetraethylammonium on canine purkinje fibre action potential configuration. (1992) (1)
Cardiac electrophysiological effects of ibuprofen in dog and rabbit ventricular preparations: Possible implication to enhanced proarrhythmic risk. (2020) (1)
Abstract 14225: Reorganized PKA-AKAP Associations in the Failing Human Heart (2010) (1)
In vivo and cellular antiarrhythmic and cardiac electrophysiological effects of desethylamiodarone in dog cardiac preparations (2022) (1)
[Non-pharmacologic treatment of atrial fibrillation]. (2003) (1)
Author Correction: Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete’s heart model (2021) (1)
Effect of Ba2+ in low concentrations on various transmembrane potassium currents in dog ventricular myocytes (2002) (1)
Neurogenic Contraction Induced by the Antiarrhythmic Compound, AVE 0118, in Rat Small Mesenteric Arteries (2014) (1)
Potassium currents in alloxan induced diabetes in rabbit hearts (2002) (1)
Novel pharmacological strategies for antiarrhythmic therapy in atrial fibrillation (2011) (1)
Late Sodium Current in Canine, Guinea Pig and Human Left Ventricular Myocardium (2020) (1)
3,8-Diazabicyclo-[3.2.1]-octane Derivatives as Analogues of Ambasilide, a Class III Antiarrhythmic Agent. (2002) (1)
Comparison of the effects of restacorin and flecainide on various cardiac transmembrane potassium currents. (1996) (1)
Pharmacological investigation of a new anti-arrhythmic agent, GYKI-23 107. (1987) (1)
INTO THE EFFECTS OF FK 352 ( A NOVEL ADENOSINE-1 RECEPTOR ANTAGONIST ) IN CIRRHOTIC PATIENTS WITH ASCITES : A PILOT STUDY (2006) (1)
SEA0400 Fails To Alter The Magnitude Of Intracellular Ca2+ Transients And Contractions In Guinea Pig Heart (2009) (1)
Pharmacology of B-GYKI-38 233 a new antiarrhythmic agent (1988) (1)
Mutations in KCNE1 Promote Cardiac Alternans in Long QT Syndrome Type 5 Rabbits (2020) (1)
Cardiac electrophysiological remodeling associated with enhanced arrhythmia susceptibility in a canine model of elite exercise (2022) (1)
Effect of biogenic amines on the automaticity of the isolated heart (1978) (1)
Ventricular cycle length irregularity affects the correlation between ventricular rate and coronary flow in isolated, Langendorff perfused guinea pig hearts. (2016) (1)
Effect of restacorin on the early and delayed after depolarization in dog Purkinje fibres. (1996) (1)
Editorial (thematic issue: perspectives of antiarrhythmic therapy: new trails, challenges and pitfalls). (2014) (0)
Interspecies Differences and Extracellular Calcium Dependence in the Vasorelaxing Effect of Cromakalim in Isolated Human, Porcine, and Canine Coronary Arteries (2010) (0)
Combined modulation of IK, ATP and IKr to reduce reverse use-dependency and repolarization heterogeneity (2014) (0)
Dual effects of bile acids on guinea pig pancreatic ductal bicarbonate secretion (2007) (0)
G004 Transcriptional profiling of ion channel genes in right-ventricular myocardial diseases: particular signature for brugada syndrome (2009) (0)
Expression alterations of ion channels for IK1 current in dilated cardiomyopathy of human heart (2008) (0)
Amidated gastrin induces proliferation via the cholecystokinin type 2 (CCK 2 ) receptor in Barrett's oesophagus (2002) (0)
The role of the slow delayed rectifier potassium current (2005) (0)
Gyki-52 713, a new 5H-2, 3-benzodiazepine compound with positive inotropic effect (1990) (0)
565 Changes in myocardial electrophysiological parameters and sensitivity to drugs in rodent experimental diabetes models (2005) (0)
Assessment of proarrhythmogenic risk for cannabidiol using dog and rabbit cardiac preparations: the electrophysiological effects on action potential and transmembrane potassium currents (2022) (0)
MiRP2 rescues long QT syndrome type 5 (2022) (0)
Conductance Changes of Na+ Channels during the Late Na+ Current Flowing under Action Potential Voltage Clamp Conditions in Canine, Rabbit, and Guinea Pig Ventricular Myocytes (2023) (0)
Endurance training-induced cardiac remodeling in a guinea pig athlete's heart model. (2022) (0)
Na+/Ca2+ exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart (2008) (0)
Examination of the role of the sympathetic nervous system in the proarrhythmic activity of dofetilide (2007) (0)
Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes (2014) (0)
Pyrimido (5,4-b) (1,4) oxazine derivatives, processes for their preparation and pharmaceutical compositions containing them oxazine derivatives and intermediates performing pyrimido (5,4-b) (1,4). (1986) (0)
Pyrimidoû5,4-b¨û1,4¨oxazine derivatives, process for their preparation, medicament containing them and intermediate pyrimidoû5,4-b¨û1,4¨oxazine derivatives (1986) (0)
Novel aminoguanidine derivatives, process for their preparation and medicaments containing same (1984) (0)
Effects of veratrine on ion currents in single rabbit cardiomyocytes. (1994) (0)
18th International Meeting of the Alpe-Adria Association of Cardiology, September 16-18, 2010, Vienna-Abstracts (2018) (0)
Measurement of intracellular pH: differences between microspectrofluorimetric and imaging systems (2006) (0)
Enterochromaffin-like (ECL) cell hyperplasia in transgenic mice with circulating progastrin but not amidated gastrin (2002) (0)
Endurance training induced cellular electrophysiological remodeling in a small and a large animal athlete’s heart model (2022) (0)
Interaction of different potassium channels in dog ventricular repolarization: Role of the repolarization reserve (2002) (0)
[Drug therapy of atrial fibrillation]. (2003) (0)
Functional modulation of post-translational processing of the gastrin precursor in the dog (1989) (0)
Poster Session 3 (2012) (0)
Cardioprotection and arrhythmias, Part 2. (2015) (0)
Characterization of acid/base transporters in parietal cells isolated from human gastric biopsy samples (2007) (0)
Frequency-dependent effects of antiarrhythmic drugs on the excitabilityand conduction time in rabbit right ventricular muscle (1987) (0)
Electrophysiological effects of the antiarrhythmic agent GYKI-23107 in dogs. (1988) (0)
Vasorelaxing effect of Levosimendan against 5-hydroxytryptamine-induced contractions in isolated human conduit bypass grafts (2006) (0)
Basal vagal nerve activity does not predict susceptibility to dofetilide-induced torsade de pointes in anaesthetized rabbits (2006) (0)
Saturday, 17 July 2010 (2010) (0)
Potential Molecular Link to Idiopathic Ventricular Fibrillation-Subunit Composition : A β Unique Cardiac Purkinje Fiber Transient Outward Current (2013) (0)
THE EFFECT OF VIRUS INFECTION ON PANCREATIC DUCT CELL SECRETION (2006) (0)
The effect of a novel highly selective inhibitor of the sodium/calcium exchanger (NCX) on cardiac automaticity and arrhythmia in in vitro and in vivo experiments (2016) (0)
IK1 a crucial component of repolarization reserve is modulated by shifts in [Ca2+]i (2010) (0)
Functional characterization of the H+/K+ ATPase in wild type and gastrin knock-out mice (2007) (0)
Pyrimido (5,4-b) (1,4) oxazinderivater, tautomer, tautomeric mixtures and acid addition salts thereof, their preparation and use as medicaments (1986) (0)
Pharmacological Modi~cation of the Dispersion of Repolarization in the Heart: Importance of the M Cells Pharmacology of M Cells (1999) (0)
Category : Review / Position Paper TITLE : Combining forces : Computational approaches for a new human-based cardiology and pharmacology (2015) (0)
GI Tract (2005) (0)
Sunday, 18 July 2010 (2010) (0)
A Possible Explanation for the Low Penetrance of Pathogenic KCNE1 Variants in Long QT Syndrome Type 5 (2022) (0)
Effect of NEP enzyme inhibitor thiorphan on isolated systemic and coronary blood vessels (2006) (0)
Characterization of the acid/base transporters in human gastric myofibroblasts (2009) (0)
PWE-062 Long-term infection of Helicobacter pylori 48GX, and output strains 12.2 and 12.3, results in hypergastrinaemia, gastric carcinoids and dysplasia in Mongolian gerbils (2010) (0)
Role of NCX1 and NHE1 in Ventricular Arrhythmia (2011) (0)
The effect of bile acids on human pancreatic duct cells (2008) (0)
Synthesis and Anti-Arrhythmic Activity of Aminoguanidine Derivatives. (1993) (0)
Nagy N et al Br J Pharmacol 2014 171(24) 5665-81 (2014) (0)
Corrigendum (2016) (0)
Advantageous antiarrhythmic and cellular electrophysiological effect of the metabolite of amiodarone (desethylamiodarone) (2018) (0)
Repolarization Reserve and Proarrhythmic Risk (2009) (0)
Genetic background of IK1 current in ventricular tissue of different species (2006) (0)
The reverse mode of the Na+/Ca2+ exchanger contributes to the pacemaker mechanism in rabbit sinus node cells (2022) (0)
POSTER SESSION ON BEHALF OF THE WORKING GROUP ON CARDIAC CELLULAR ELECTROPHYSIOLOGY Atrium specific kir3.x determines inducibility and dynamics of fibrillation by regulating voltage-dependent alternans in atrial cardiomyocyte monolayers (2013) (0)
Abstract 1094: Transcription Signature of Ion Channel Genes in Brugada Syndrome (2006) (0)
Bench to bedside application of ... (2011) (0)
Sotalol and mexiletine: A combination of rate-dependent electrophysiological effects (1990) (0)
The bioactivity of multidrug resistance transporter proteins is increased in human esophagus cancer-derived myofibroblasts (2008) (0)
Electrophysiological effects of tiracizin and its metabolites in dog cardiac Purkinje fibers. (1995) (0)
Application of Neutral Networks in Structure—Activity Relationships (1999) (0)
Comparison oftheEffect ofClass IAAntiarrhythmic Drugson Transmembrane Potassium Currents inRabbit Ventricular Myocytes (2003) (0)
Expression of orexin-1 receptors by rat vagal afferent neurones (2002) (0)
Effect of antiarrhythmic drugs on the range of premature action potential durations (APD) in cardiac Purkinje fibers (1984) (0)
Effect of eliprodil on cardiac repolarization (2002) (0)
Effect of hypoxia in non-ischaemic coronary arteries isolated from normal and ischaemic canine hearts (2002) (0)
The hidden cardiotoxic effect of rofecoxib on rabbit ventricular preparations (2022) (0)
Shared gene expression profile between aging and diseased hearts in man (2017) (0)
Role of gap junctions in acute ischaemia-induced arrhythmias and in the antiarrhythmic effect of ischaemic preconditioning (2008) (0)
Is selective late sodium current inhibition different from class I/B antiarrhythmic action? Comparison of the effects of GS967 to mexiletine in canine ventricular myocardium (2021) (0)
Expression in rat G-cells of vesicular monoamine transporter type1 (VMAT1) and its role in modulating conversion of G34 to G17 (1998) (0)
New derivatives of alkylenediamine, process for preparing them and medicaments containing them (1982) (0)
The effects of trypsin on pancreatic ductal epithelia (2006) (0)
A novel LQT5 transgenic rabbit model for the assessment of proarrhythmic side effects of developmental compounds. (2014) (0)
Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy (2017) (0)
Bile acids cause acidification and CA2+-signalling in guinea pig pancreatic duct cells (2006) (0)
Study off GYKI-46.544, a new bradycardizing calcium antagonist in isolated cardiovascular preparations (1990) (0)
Analogifoerfarande Foer framstaellning of a alkylendiaminderivat with the Pharmacological Effect. (1982) (0)
The role of transient outward potassium current in mammalian heart (2007) (0)
Examination of the role of the Na+/Ca2+ exchanger in the genesis of the dofetilide-induced torsades de pointes (2007) (0)
Analogifremgangsmaade for the preparation of the alkylenediamine or N-oxide or acid addition salts thereof (1982) (0)
P475Investigation of cardiac morphological and electrophysiological changes of dogs after long time intensive exercise (2018) (0)
Selective inhibition of Na+/Ca2+ exchanger increases contractility in the isolated rat heart (2006) (0)
The inhibitory effect of Substance P on HCO3- secretion from the guinea pig microperfused pancreatic ducts (2005) (0)
A reference architecture for functional interoperability in robotics (2021) (0)
P640New in vitro model for proarrhythmia screening: iks inhibition potentiates the qtc prolonging effect of ikr inhibitors in isolated guinea pig hearts (2014) (0)
DERIVATIVES 3 (2H) -pyridazinone AND METHOD FOR PREPARING. (1992) (0)
Species dependent differences in the inhibition of various potassium currents and in their effects on repolarization in cardiac ventricular muscle. (2022) (0)
213 Calpain‐I sensitive proteins of the human myocardium (2003) (0)
Sudden cardiac death and cardioprotection. (2013) (0)
Phosphorylation of human progastrin by Golgi membrane kinase (1994) (0)
Characterization of a new acute necrotizing pancreatitis model induced by L-ornithine (2008) (0)
A Novel In Silico Human Cardiac Purkinje Cell Model to Investigate Drug Safety and Efficacy (2017) (0)
Rabbit a reliable human like model in preclinical cardiac electrophysiological safety testing (2018) (0)
[Ca2+]i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium (2013) (0)
ndocardial versus epicardial differences in L-type calcium current in canine ventricular myocytes studied by action potential voltage clamp a a a a b ́ ́ ́ ́ ́ ̈ ̈ ́ ́ ́ ́ (2003) (0)
Effect of ivabradine in heart failure: a meta-analysis of heart failure patients with reduced versus preserved ejection fraction. (2021) (0)
83rd Annual Meeting DPG. Abstracts pp S65-S87 (2004) (0)
THE EFFECT OF BILE ACIDS ON PANCREATIC DUCTAL EPITHELIA (2006) (0)
Alkylenediamine, process for their production and these compounds containing drug (1982) (0)
The targeted disruption of the gastrin gene in mice results in decreased proliferation of the stomach and colon in response to reffeding (1998) (0)
Alkylenediamine N-oxides and acid addition salts thereof, their preparation and use as anti-arrhythmic medicaments (1982) (0)
Author response: Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block (2019) (0)
Poster session 3 (2001) (0)
Familial Idiopathic Ventricular Fibrillation Linked to Chromosome 7q36 Harboring DPP6 (2011) (0)
CELLULAR ELECTROPHYSIOLOGICAL EFFECTS OF ANTIARRHYTHMIC DRUGS (2019) (0)
Abstract 4014: Connexin43 Remodeling in Septal Biopsies as a Sensitive Marker for Diagnosing Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (2009) (0)
Personalised health education against the health damage of COVID-19 epidemic in Hungary (PROACTIVE-19): protocol of an adaptive randomised controlled clinical trial. (2020) (0)
P604Docosahexaenoic acid acts as QT-shortening agent with genotype-tspecific beneficial effects in transgenic LQT1, LQT2, LQT5 and LQT2-5 rabbit models (2018) (0)
Kinetics of gastrin production in omeprazole-treated patients (1991) (0)
Abstract 11445: DPP6 Contributes to Purkinje Transient Outward Current: A Potential Molecular Mechanism for Idiopathic Ventricular Fibrillation (2010) (0)
Cardiac remodeling accompanied by increased arrhythmia susceptibility in a dog model of chronic high-intensity endurance training (2022) (0)
The non-conjugated chenodeoxycholate stimulates the luminal Cl-/HCO3- exchanger via IP3-mediated Ca2+-signalling in guinea pig pancreatic ducts (2007) (0)
Potential role of potassium currents in the repolarization reserve: the importance of cardiac repolarization reserve in safety pharmacology (2014) (0)
Is Selective Late Na+ Current Inhibition Different From Class I/B Antiarrhythmic Action? Comparison of The Effects of GS967 to Mexiletine in Canine Ventricular Myocardium (2021) (0)
Repolarizáló káliumáramok tulajdonságainak vizsgálata sinusritmusú és pitvarfibrilláló kutyákból izolált pitvari szívizomsejteken = Properties of several repolarizing potassium currents in atrial cadiomyocytes isolated from dogs in sinus rhythm and atrial fibrillation (2017) (0)
IKr channels analysis (alpha- and beta-subunits) in human and dog hearts (2007) (0)
BJP NCX and Torsades 2009 (2014) (0)
Enterochromaffin-like (ECL) cell function in transgenic mice expressing gastrin in pancreatic β-cells (1998) (0)
The Na+/Ca2+ exchange inhibitor SEA0400 fails to enhance cytosolic Ca2+ transient and contractility in isolated canine ventricular myocytes (2008) (0)
801 Interaction of C-type natriuretic peptide and NEP-enzyme inhibitors on the tone of isolated porcine coronary artery (2003) (0)
Ligand Binding and Gating in HCN 2 Channels (2009) (0)
Effects of diclofenac on ventricular muscle repolarization: proarrhythmic implications (2011) (0)
RESEARCH PAPER Combined pharmacological block of I Kr and I Ks increases short-term QT interval variability and provokes torsades de pointes (2007) (0)
Species dependent cardiac electrophysiological effects elicited by various potassium channel blocking drugs. (2021) (0)
Novel human Purkinje electrophysiology model for drug safety and efficacy mechanistic investigations (2020) (0)
2nd European Section Meeting of the International Academy of Cardiovascular Sciences (IACS) (2015) (0)
The comparison of the kinetics of of rapid and slow delayed rectifier currents in undiseased human, dog, rabbit and guinea pig ventricular myocytes (2013) (0)
The possible role of NCX in the generation of cardiac arrhythmias (2012) (0)
Electrophysiological Evaluation of Novel Blockers of If Current (2009) (0)
RESEARCH PAPER Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial ﬁbrillation (2013) (0)
Estimates of INaCa during ICa in rat ventricular myocytes (1992) (0)
EVALUATION OF THE RELATIONSHIP BETWEEN PLASMA GLUCOSE LEVEL AND SHORT-TERM BEAT-TO-BEAT QT INTERVAL VARIABILITY IN SUBJECTS WITH NORMOGLYCEMIA: PP.LB1.459 (2011) (0)
P511In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs (2017) (0)
A novel possibility for gene transfer into the duct cells using non-replicating pseudorabies virus variants (2005) (0)
11 Impairment of repolarisation reserve by combined pharmacological inhibition of ventricular potassium channels in rabbits: implications for arrhythmia prediction (2010) (0)
THE EFFECTS OF TRYPSIN ON PANCREATIC PAR-2 RECEPTORS (2006) (0)
Disruption of sodium homeostasis in cardiac disease In the session on ‘ Disruption of Na + homeostasis (2015) (0)
Comparative evaluation of cardiac actions of some new positive inotropic compounds with different modes of action (1987) (0)
Abstracts: Pharmacology (Basic Science) (2009) (0)
Ion channels alteration in dilated cardiomyopathy in human heart (2007) (0)
Shift in Na+/Ca2+exchange balance modulates the inotropic consequences of the NCX inhibition (2014) (0)
Pseudorabies virus infection stimulates pancreatic ductal HCO3- secretion (2005) (0)
Addendum: Electrical restitution in ventricular myocardium (Journal of Clinical Physiology (1996) 16(4) (339-351)) (1996) (0)
REAL-TIME MULTIPLEX PCR ASSAY FOR INVESTIGATION OF THE KINESIN LIGHT-CHAIN 1 GENE A 185 C AND C 406 T MUTATIONS (2011) (0)
Effect of class II-III-IV antiarrhythmic drugs on the premature action potential duration (APD) in cardiac Purkinje and ventricular muscle fibers (1987) (0)
Correction (1875) (0)
The Inhibition of the Small-Conductance Ca2+-Activated Potassium Channels Decreases the Sinus Node Pacemaking during Beta-Adrenergic Activation (2022) (0)

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