Andrea Biondi

Q: What Schools Are Affiliated With Andrea Biondi

Andrea Biondi is affiliated with the following schools: University of Milan, University of L'Aquila, University of Oxford, University of Perugia, University of Pavia, Hannover Medical School, University of Milano-Bicocca, Sapienza University of Rome, University of Münster

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Andrea Biondi

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#4555

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Philosophy

Andrea Biondi's Degrees

PhD Biomedical Sciences University of Milan
Doctorate Medicine University of Milan

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Andrea Biondi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. (2003) (2541)
Autoantibodies against type I IFNs in patients with life-threatening COVID-19 (2020) (1744)
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 (2020) (1524)
Genomewide Association Study of Severe Covid-19 with Respiratory Failure (2020) (1425)
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease (1999) (1191)
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. (2009) (790)
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study. (2010) (697)
Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration. (2015) (644)
Prenatal origin of acute lymphoblastic leukaemia in children (1999) (634)
Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood (1998) (617)
Acute promyelocytic leukemia: from genetics to treatment. (1994) (537)
IL-1 stimulates IL-6 production in endothelial cells. (1989) (510)
Molecular Remission in PML/RARα-Positive Acute Promyelocytic Leukemia by Combined All-trans Retinoic Acid and Idarubicin (AIDA) Therapy (1997) (488)
Mapping the human genetic architecture of COVID-19 (2021) (455)
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial (2007) (452)
Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region (2002) (385)
Cross-Linking of the Mannose Receptor on Monocyte-Derived Dendritic Cells Activates an Anti-Inflammatory Immunosuppressive Program 1 (2003) (372)
Monokine production by microglial cell clones (1989) (362)
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study. (2011) (356)
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia (2008) (344)
Recombinant human interleukin 5 is a selective eosinophil chemoattractant (1989) (337)
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias (2011) (321)
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties. (1991) (317)
Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials (1997) (308)
Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. (2001) (303)
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia (2013) (301)
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. (2004) (294)
Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. (2003) (292)
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations (2006) (288)
Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia. (1992) (281)
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. (2006) (273)
Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study (2012) (273)
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome (2008) (272)
Early Detection of Relapse by Prospective Reverse Transcriptase-Polymerase Chain Reaction Analysis of the PML/RARα Fusion Gene in Patients With Acute Promyelocytic Leukemia Enrolled in the GIMEMA-AIEOP Multicenter “AIDA” Trial (1998) (265)
Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus. (1991) (260)
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths (2021) (257)
Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. (2009) (252)
Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia (1992) (246)
Molecular analysis of the progression from Helicobacter pylori-associated chronic gastritis to mucosa-associated lymphoid-tissue lymphoma of the stomach. (1998) (246)
Molecular remission in PML/RAR alpha-positive acute promyelocytic leukemia by combined all-trans retinoic acid and idarubicin (AIDA) therapy. Gruppo Italiano-Malattie Ematologiche Maligne dell'Adulto and Associazione Italiana di Ematologia ed Oncologia Pediatrica Cooperative Groups. (1997) (224)
An immune-based biomarker signature is associated with mortality in COVID-19 patients (2020) (216)
An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. (2012) (215)
Prognostic value of minimal residual disease in relapsed childhood acute lymphoblastic leukaemia (2001) (208)
Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD123‐specific chimeric antigen receptor (2013) (200)
Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis (2002) (199)
Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000. (2016) (194)
GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children. (2005) (191)
Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients. (2014) (190)
Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity. (2007) (190)
RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML) (1999) (189)
Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases (1998) (187)
Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype. (2005) (184)
Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group. (2014) (181)
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 (2021) (178)
Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study. (2007) (173)
Platelet-lysate-expanded mesenchymal stromal cells as a salvage therapy for severe resistant graft-versus-host disease in a pediatric population. (2010) (173)
KIT activating mutations: incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication. (2004) (164)
Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels (2020) (162)
Heteroduplex analysis of T-cell receptor gamma gene rearrangements for diagnosis and monitoring of cutaneous T-cell lymphomas. (1994) (161)
Results of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia. (2013) (156)
Extracorporeal Photochemotherapy Is Accompanied by Increasing Levels of Circulating CD4+CD25+GITR+Foxp3+CD62L+ Functional Regulatory T-Cells in Patients With Graft-Versus-Host Disease (2007) (155)
Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL. (2002) (154)
Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration (2009) (147)
Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: Multicentric assessment is feasible (2008) (143)
Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia. (1992) (142)
Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study. (2010) (141)
Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study. (2019) (137)
ALL-1 gene at chromosome 11q23 is consistently altered in acute leukemia of early infancy. (1993) (129)
IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL. (2014) (129)
Interleukin-17–Producing T-Helper Cells as New Potential Player Mediating Graft-Versus-Host Disease in Patients Undergoing Allogeneic Stem-Cell Transplantation (2009) (124)
The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case. (2001) (120)
The tyrosine kinase abl-related gene ARG is fused to ETV6 in an AML-M4Eo patient with a t(1;12)(q25;p13): molecular cloning of both reciprocal transcripts. (1999) (119)
Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry (2016) (119)
IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia. (2018) (117)
Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia. (2017) (114)
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition. (2010) (114)
Italian cancer figures, report 2012: Cancer in children and adolescents. (2013) (111)
Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts (2013) (111)
Molecular follow-up in gastric mucosa-associated lymphoid tissue lymphomas: early analysis of the LY03 cooperative trial. (2002) (110)
Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors (2010) (107)
Detection of prognostically relevant genetic abnormalities in childhood B‐cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin‐Frankfürt‐Münster study group (2010) (105)
New policies to address the global burden of childhood cancers. (2013) (105)
Infant acute leukemias show the same biased distribution of ALL1 gene breaks as topoisomerase II related secondary acute leukemias. (1997) (105)
Lessons after the early management of the COVID-19 outbreak in a pediatric transplant and hemato-oncology center embedded within a COVID-19 dedicated hospital in Lombardia, Italy. Estote parati (2020) (102)
Managing children with chronic myeloid leukaemia (CML) (2014) (102)
Comparison of different suicide-gene strategies for the safety improvement of genetically manipulated T cells. (2012) (102)
Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leukemia (2012) (98)
Detection of minimal residual disease in pediatric acute lymphoblastic leukemia (2013) (97)
Early advice on managing children with cancer during the COVID‐19 pandemic and a call for sharing experiences (2020) (96)
Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia (2012) (96)
Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARalpha fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multicenter "AIDA" trial. GIMEMA-AIEOP Multicenter "AIDA" Trial. (1998) (95)
Detection of ALL-1/AF4 fusion transcript by reverse transcription-polymerase chain reaction for diagnosis and monitoring of acute leukemias with the t(4;11) translocation. (1993) (95)
Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy. (2016) (91)
Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL (2001) (88)
Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia (2016) (88)
Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial (2020) (87)
Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse (2018) (87)
AIEOP‐BFM Consensus Guidelines 2016 for Flow Cytometric Immunophenotyping of Pediatric Acute Lymphoblastic Leukemia (2018) (86)
Somatic PTPN11 mutations in childhood acute myeloid leukaemia (2005) (85)
Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: a retrospective analysis. (2016) (84)
A wide role for NOTCH1 signaling in acute leukemia. (2005) (84)
Molecular monitoring of childhood acute lymphoblastic leukemia using antigen receptor gene rearrangements and quantitative polymerase chain reaction technology. (2005) (83)
C-kit+ cardiac progenitors exhibit mesenchymal markers and preferential cardiovascular commitment. (2011) (83)
Extramedullary involvement in patients with acute promyelocytic leukemia (1998) (82)
Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19 (2022) (81)
Identification of preleukemic precursors of hyperdiploid acute lymphoblastic leukemia in cord blood (2004) (81)
Establishment of bone marrow and hematopoietic niches in vivo by reversion of chondrocyte differentiation of human bone marrow stromal cells. (2014) (81)
Molecular evaluation of response to all-trans-retinoic acid therapy in patients with acute promyelocytic leukemia. (1991) (79)
Asociación de Hemato‐Oncología Pediátrica de Centro América (AHOPCA): A model for sustainable development in pediatric oncology (2014) (79)
Children with cancer in the time of COVID‐19: An 8‐week report from the six pediatric onco‐hematology centers in Lombardia, Italy (2020) (79)
Microgranular variant of acute promyelocytic leukemia in children. (1992) (78)
IDUA mutational profiling of a cohort of 102 European patients with mucopolysaccharidosis type I: identification and characterization of 35 novel α‐L‐iduronidase (IDUA) alleles (2011) (77)
Regulatory T Cells and Extracorporeal Photochemotherapy: Correlation With Clinical Response and Decreased Frequency of Proinflammatory T Cells (2009) (76)
Minimal residual disease before and after transplantation for childhood acute lymphoblastic leukaemia: is there any room for intervention? (2014) (76)
Modulation of antigen expression in B‐cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: Evidence for a drug‐induced regulatory phenomenon. Results of the AIEOP‐BFM‐ALL‐FLOW‐MRD‐Study Group (2010) (76)
Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol. (2009) (75)
Delineation of multiple deleted regions in 7q in myeloid disorders (1999) (75)
The ABO blood group locus and a chromosome 3 gene cluster associate with SARS-CoV-2 respiratory failure in an Italian-Spanish genome-wide association analysis (2020) (73)
Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks (2009) (73)
Analysis of a Global Registration Trial of the Efficacy and Safety of CTL019 in Pediatric and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (2016) (73)
Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy. (2008) (72)
CD2 expression in acute promyelocytic leukemia is associated with microgranular morphology (FAB M3v) but not with any PML gene breakpoint. (1995) (72)
Childhood high-risk acute lymphoblastic leukemia in first remission: results after chemotherapy or transplant from the AIEOP ALL 2000 study. (2014) (71)
Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia. (2004) (70)
Expression of CD58 in normal, regenerating and leukemic bone marrow B cells: implications for the detection of minimal residual disease in acute lymphocytic leukemia. (2003) (70)
What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia? (2013) (68)
Characterization of in vitro migratory properties of anti-CD19 chimeric receptor-redirected CIK cells for their potential use in B-ALL immunotherapy. (2006) (66)
t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukemia (2000) (65)
How I treat infant leukemia. (2019) (65)
Microclustering of TEL‐AML1 translocation breakpoints in childhood acute lymphoblastic leukemia (2000) (64)
Enzymatic replacement therapy for Hunter disease: Up to 9 years experience with 17 patients (2015) (63)
Characterization of platelet lysate cultured mesenchymal stromal cells and their potential use in tissue-engineered osteogenic devices for the treatment of bone defects. (2010) (63)
Sleeping Beauty-engineered CAR T cells achieve anti-leukemic activity without severe toxicities. (2020) (61)
Prednisone induces immunophenotypic modulation of CD10 and CD34 in nonapoptotic B‐cell precursor acute lymphoblastic leukemia cells (2008) (60)
Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial. (2018) (60)
A human immunodeficiency virus type 1 pol gene-derived sequence (cPPT/CTS) increases the efficiency of transduction of human nondividing monocytes and T lymphocytes by lentiviral vectors. (2002) (59)
Gemtuzumab ozogamicin in pediatric CD33-positive acute lymphoblastic leukemia: first clinical experiences and relation with cellular sensitivity to single agent calicheamicin (2003) (59)
In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor. (2011) (59)
Front-Line Treatment of Acute Promyelocytic Leukemia with AIDA Induction Followed by Risk-Adapted Consolidation: Results of the AIDA-2000 Trial of the Italian GIMEMA Group. (2004) (59)
FLT3 internal tandem duplication in childhood acute myeloid leukaemia: association with hyperleucocytosis in acute promyelocytic leukaemia (2003) (58)
DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4 (2010) (57)
ALL-1 gene rearrangements in acute myeloid leukemia: association with M4-M5 French-American-British classification subtypes and young age. (1995) (57)
Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000). (2017) (57)
The SIOPE strategic plan: a European cancer plan for children and adolescents (2015) (56)
Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak (2020) (56)
Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia. (2011) (56)
Novel activating mutations lacking cysteine in type I cytokine receptors in acute lymphoblastic leukemia. (2014) (56)
PAX5/TEL acts as a transcriptional repressor causing down-modulation of CD19, enhances migration to CXCL12, and confers survival advantage in pre-BI cells. (2008) (55)
Protocol‐based treatment for children with cancer in low income countries in Latin America: A report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)—Part II (2007) (55)
Inhibition of granulocyte-macrophage colony-stimulating factor prevents dissemination and induces remission of juvenile myelomonocytic leukemia in engrafted immunodeficient mice. (1997) (54)
The silent mutational landscape of infant MLL‐AF4 pro‐B acute lymphoblastic leukemia (2013) (54)
Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor a (2017) (52)
Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome (2017) (52)
Protumoral role of monocytes in human B-cell precursor acute lymphoblastic leukemia: involvement of the chemokine CXCL10. (2012) (51)
The immunophenotype in infant acute lymphoblastic leukaemia: correlation with clinical outcome. An Italian multicentre study (AIEOP) (1992) (51)
Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BB-zeta activating signal. (2007) (50)
miRNA-regulated gene expression differs in celiac disease patients according to the age of presentation (2015) (50)
Clonality profile in relapsed precursor-B-ALL children by GeneScan and sequencing analyses. Consequences on minimal residual disease monitoring (2003) (50)
Identification of new partner chromosomes involved in fusions with the ETV6 (TEL) gene in hematologic malignancies (1998) (50)
Tyrosine kinase inhibitors in BCR-ABL positive acute lymphoblastic leukemia (2015) (49)
Immunoglobulin heavy chain Diversity genes rearrangement pattern indicates that MALT‐type gastric lymphoma B cells have undergone an antigen selection process (1997) (48)
Haematopoietic stem cell transplantation for refractory Langerhans cell histiocytosis: outcome by intensity of conditioning (2015) (48)
Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia (2007) (48)
A simplified minimal residual disease polymerase chain reaction method at early treatment points can stratify children with acute lymphoblastic leukemia into good and poor outcome groups (2009) (47)
Rearrangements of the RAR‐α gene in acute promyelocytic leukaemia: (1991) (47)
T‐cell lymphoblastic lymphoma shows differences and similarities with T‐cell acute lymphoblastic leukemia by genomic and gene expression analyses (2011) (47)
Dexamethasone in Induction Can Eliminate One Third of All Relapses in Childhood Acute Lymphoblastic Leukemia (ALL): Results of An International Randomized Trial in 3655 Patients (Trial AIEOP-BFM ALL 2000) (2008) (47)
Clinical relevance of residual disease monitoring by polymerase chain reaction in patients with ALL‐1/AF‐4 positive‐acute lymphoblastic leukaemia (1996) (46)
TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals (2020) (46)
Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement (2014) (46)
Optimal response to thalidomide in a patient with thalassaemia major resistant to conventional therapy. (2010) (45)
Hepato‐splenic γδ T‐cell lymphoma: A rare entity mimicking the hemophagocytic syndrome (1999) (45)
Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling. (2015) (45)
Neutralizing type‐I interferon autoantibodies are associated with delayed viral clearance and intensive care unit admission in patients with COVID‐19 (2021) (44)
Neonatal bone marrow transplantation prevents bone pathology in a mouse model of mucopolysaccharidosis type I. (2015) (43)
Innovative two-step negative selection of granulocyte colony-stimulating factor-mobilized circulating progenitor cells: adequacy for autologous and allogeneic transplantation. (1998) (43)
Characterization of the human myeloid leukemia‐derived cell line GF‐D8 by multiplex fluorescence in situ hybridization, subtelomeric probes, and comparative genomic hybridization (1999) (43)
Phase II Study of Sequential Infusion of Donor Lymphocyte Infusion and Cytokine-Induced Killer Cells for Patients Relapsed after Allogeneic Hematopoietic Stem Cell Transplantation. (2017) (42)
Familial partial monosomy 7 and myelodysplasia: different parental origin of the monosomy 7 suggests action of a mutator gene. (2001) (42)
Identification of a novel molecular partner of the E2A gene in childhood leukemia (1999) (42)
Analysis of p53 gene mutations in acute myeloid leukemia (1994) (41)
Immunosuppression does not affect human bone marrow mesenchymal stromal cell efficacy after transplantation in traumatized mice brain (2014) (41)
Classification of deletions and identification of cryptic translocations involving 7q by fluorescence in situ hybridization (FISH). (1996) (40)
Detection of minimal residual disease identifies differences in treatment response between TALL and precursor BALL (2002) (40)
Molecular analysis of 30 mucopolysaccharidosis type I patients: evaluation of the mutational spectrum in Italian population and identification of 13 novel mutations (2002) (39)
Defining and listing very rare cancers of paediatric age: consensus of the Joint Action on Rare Cancers in cooperation with the European Cooperative Study Group for Pediatric Rare Tumors. (2019) (39)
Outcome of very late relapse in children with acute lymphoblastic leukemia. (2004) (38)
Prognostic discrimination based on the EUTOS long-term survival score within the International Registry for Chronic Myeloid Leukemia in children and adolescents (2017) (38)
Immunogenotype Changes Prevail in Relapses of Young Children with TEL-AML1-Positive Acute Lymphoblastic Leukemia and Derive Mainly from Clonal Selection (2005) (38)
Somatically acquired JAK 1 mutations in adult acute lymphoblastic leukemia " (2008) (38)
Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform (2016) (37)
Clinical features and outcome of SIL/TAL1-positive T-cell acute lymphoblastic leukemia in children and adolescents: a 10-year experience of the AIEOP group (2015) (37)
Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment response (2002) (36)
Comparative analysis of multilineage properties of mesenchymal stromal cells derived from fetal sources shows an advantage of mesenchymal stromal cells isolated from cord blood in chondrogenic differentiation potential (2014) (36)
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias (2011) (36)
Mutations of JAK 2 in acute lymphoblastic leukaemias associated with Down ’ s syndrome (2008) (36)
Chimeric T-cell receptors: new challenges for targeted immunotherapy in hematologic malignancies. (2007) (36)
Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia (2010) (36)
Role of CXCR4‐mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia (2016) (35)
Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein (2004) (34)
Long‐term results of high‐dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience (2015) (34)
Heterogeneity of the 7q36 breakpoints in the t(7;12) involving ETV6 in infant leukemia (2003) (33)
Late mortality and causes of death among 5-year survivors of childhood cancer diagnosed in the period 1960-1999 and registered in the Italian Off-Therapy Registry. (2019) (33)
Human cord blood CD34+ progenitor cells acquire functional cardiac properties through a cell fusion process. (2011) (33)
In vitro modulatory effects of interleukin‐3 on macrophage activation induced by interleukin‐2 (1993) (32)
CD40 activation of BCP-ALL cells generates IL-10-producing, IL-12-defective APCs that induce allogeneic T-cell anergy. (2004) (32)
Acute undifferentiated leukemia with CD7+ and CD13+ immunophenotype. Lack of molecular lineage commitment and association with poor prognostic features (1992) (32)
Rapid retroviral infection of human haemopoietic cells of different lineages: efficient transfer in fresh T cells (1998) (31)
Biochemical and genetic defects underlying human congenital hypotransferrinemia. (2000) (31)
Mesenchymal Stromal Cells Do Not Increase the Risk of Viral Reactivation Nor the Severity of Viral Events in Recipients of Allogeneic Stem Cell Transplantation (2012) (31)
Development of an algorithm for the management of cervical lymphadenopathy in children: consensus of the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Society of Pediatric Infectious Diseases and the Italian Society of Pediatric Otorhinolaryngology (2015) (30)
Emergency department use by paediatric patients in Lombardy Region, Italy: a population study (2018) (30)
Risk factors for relapse in childhood acute lymphoblastic leukemia: prediction and prevention (2015) (30)
Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies. (2006) (29)
Catch me if you can: how AML and its niche escape immunotherapy (2021) (29)
Rituximab unveils hypogammaglobulinemia and immunodeficiency in children with autoimmune cytopenia. (2019) (29)
Reverse transcriptase/polymerase chain reaction follow‐up and minimal residual disease detection in t(1;19)‐positive acute lymphoblastic leukaemia (1996) (29)
Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols (2019) (28)
Allogeneic mesenchymal stem cell infusion for the stabilization of focal segmental glomerulosclerosis. (2013) (28)
The presence of mutated and deleted PTEN is associated with an increased risk of relapse in childhood T cell acute lymphoblastic leukaemia treated with AIEOP‐BFM ALL protocols (2018) (28)
CD123 AML targeting by chimeric antigen receptors (2014) (28)
WT1 gene expression: useful marker for minimal residual disease in childhood myelodysplastic syndromes and juvenile myelo‐monocytic leukemia? (2004) (28)
Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the Treatment of Acute Lymphoblastic Leukemia. (2018) (28)
Expression of lineage‐restricted protein tyrosine kinase genes in human natural killer cells (1991) (27)
The washouts of discarded bone marrow collection bags and filters are a very abundant source of hMSCs. (2009) (27)
Correlation of Serum Interleukin-2 Levels, Soluble Interleukin-2 Receptors and T Lymphocyte Subsets in Cancer Patients (1990) (26)
PTX3 as a Potential Novel Tool for the Diagnosis and Monitoring of Pulmonary Fungal Infections in Immuno-compromised Pediatric Patients (2008) (26)
Diagnosis and incidence of acute promyelocytic leukemia (FAB M3 and M3 variant) in childhood [letter] (1993) (26)
Adolescents’ Health Awareness and Understanding of Cancer and Tumor Prevention: When and Why an Adolescent Decides to Consult a Physician (2016) (26)
Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol (2020) (25)
Hurler disease bone marrow stromal cells exhibit altered ability to support osteoclast formation. (2012) (25)
Defining the correct role of minimal residual disease tests in the management of acute lymphoblastic leukaemia (2011) (25)
Molecular Pathways and Respiratory Involvement in Lysosomal Storage Diseases (2019) (25)
Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia (2015) (25)
Collateral effects of COVID‐19 pandemic in pediatric hematooncology: Fatalities caused by diagnostic delay (2020) (24)
Fusion of ETV 6 to the Caudal-Related Homeobox Gene CDX 2 in Acute Myeloid Leukemia (1999) (24)
Hepato-splenic gammadelta T-cell lymphoma: a rare entity mimicking the hemophagocytic syndrome. (1999) (24)
Targeting CD33 in Chemoresistant AML Patient-Derived Xenografts by CAR-CIK Cells Modified with an Improved SB Transposon System. (2020) (24)
Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study (2019) (24)
Unique genotypic features of infant acute lymphoblastic leukaemia at presentation and at relapse (1992) (24)
Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia. (2003) (23)
Acute myeloid leukemia and novel biological treatments: monoclonal antibodies and cell-based gene-modified immune effectors. (2013) (23)
Expression of CD 58 in normal , regenerating and leukemic bone marrow B cells : implications for the detection of minimal residual disease in acute lymphocytic leukemia (2003) (23)
The sensitivity of acute lymphoblastic leukemia cells carrying the t(12;21) translocation to campath-1H-mediated cell lysis. (2006) (23)
COVID-19 in Immunosuppressed Children (2021) (23)
CA180-372: An International Collaborative Phase 2 Trial of Dasatinib and Chemotherapy in Pediatric Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) (2017) (22)
Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): Review from an international consensus conference (2010) (22)
Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms (2017) (22)
CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia (2014) (22)
IGH and IGK gene rearrangements as PCR targets for pediatric Burkitt's lymphoma and mature B-ALL MRD analysis (2009) (21)
Additional cytogenetic abnormalities and variant t(9;22) at the diagnosis of childhood chronic myeloid leukemia: The experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents (2017) (21)
Long-term survivors of childhood cancer: cure and care—the Erice Statement (2006) revised after 10 years (2016) (2018) (21)
Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo (2017) (21)
Failure of interferon-γ pre-treated mesenchymal stem cell treatment in a patient with Crohn's disease. (2015) (20)
In Vitro Comparison of Three Different Chimeric Receptor-modified Effector T-cell Populations for Leukemia Cell Therapy (2011) (20)
Possible Role of Pandemic AH1N1 Swine Flu Virus in a Childhood Leukemia Cluster (2017) (20)
The International Registry for Chronic Myeloid Leukemia (CML) in Children and Adolescents (I-CML-Ped-Study): Objectives and Preliminary Results (2012) (20)
Childhood acute lymphoblastic leukemia in Nicaragua: Long‐term results in the context of an international cooperative program (2014) (20)
Autoreactive B cell clones in marginal-zone B cell lymphoma (MALT lymphoma) of the stomach (1998) (20)
Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia. (2013) (20)
Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study. (2021) (20)
Intrauterine diagnosis and management of transient myeloproliferative disorder. (1995) (19)
A single high dose of idarubicin combined with high‐dose ARA‐C for treatment of first relapse in childhood ‘high‐risk’ acute lymphoblastic leukaemia: a study of the AIEOP group (2002) (19)
Combined cord blood and bone marrow transplantation from the same human leucocyte antigen‐identical sibling donor for children with malignant and non‐malignant diseases (2015) (19)
High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia (2017) (19)
Transposon-Based CAR T Cells in Acute Leukemias: Where Are We Going? (2020) (18)
Spiritual Support for Adolescent Cancer Patients: A Survey of Pediatric Oncology Centers in Italy and Spain (2016) (18)
GMP-based CD133+ cells isolation maintains progenitor angiogenic properties and enhances standardization in cardiovascular cell therapy (2009) (18)
Diagnosis and incidence of acute promyelocytic leukemia (FAB M3 and M3 variant) in childhood. (1993) (18)
CyclinD1 Down‐Regulation and Increased Apoptosis Are Common Features of Cohesinopathies (2016) (18)
Pro‐inflammatory cytokines favor the emergence of ETV6‐RUNX1‐positive pre‐leukemic cells in a model of mesenchymal niche (2020) (18)
The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies (2022) (17)
ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells (2018) (17)
Reciprocal translocation t(12;13)(p13;q14) in acute nonlymphoblastic leukemia: report and cytogenetic analysis of two cases. (1994) (17)
Clinical and molecular genetic characterization of wild-type MLL infant acute lymphoblastic leukemia identifies few recurrent abnormalities (2016) (17)
In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor Running title: CD23 CAR-targeting for CLL immunotherapy Keywords: CLL, Chimeric T-cell receptor, CD23, Immunotherapy, Cell Therapy (2011) (17)
Acute Myeloid Leukemia Targeting by Chimeric Antigen Receptor T Cells: Bridging the Gap from Preclinical Modeling to Human Studies. (2017) (17)
Glutathione S-transferase homozygous deletions and relapse in childhood acute lymphoblastic leukemia: a novel study design in a large Italian AIEOP cohort. (2012) (17)
Modeling Cornelia de Lange syndrome in vitro and in vivo reveals a role for cohesin complex in neuronal survival and differentiation (2018) (17)
Corrigendum: Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia (Leukemia (2016) 30 (1672-1681) DOI: 10.1038/leu.2016.69) (2016) (17)
Absent B cells, agammaglobulinemia, and hypertrophic cardiomyopathy in Folliculin Interacting Protein 1 deficiency. (2020) (17)
Rituximab induces different but overlapping sets of genes in human B-lymphoma cell lines (2005) (17)
NIPBL: a new player in myeloid cell differentiation (2019) (17)
Transcriptional and post‐transcriptional regulation of IL‐1β, IL‐6 and TNF‐α genes in chronic lymphocytic leukaemia (1993) (17)
Minimal residual disease as a surrogate marker for risk assignment to ALL patients. (2003) (16)
Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4+ Infant ALL (2018) (16)
Donor-derived CD19-targeted T cells in allogeneic transplants (2015) (16)
A (15;17) translocation not associated with acute promyelocytic leukaemia (1996) (16)
Molecular remission induced by gemtuzumab ozogamicin associated with donor lymphocyte infusions in t(4;11) acute lymphoblastic leukemia relapsed after transplantation (2003) (16)
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia (2021) (16)
LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients (2015) (16)
Molecular characterization of a new recombination of the SIL/TAL‐1 locus in a child with T‐cell acute lymphoblastic leukaemia (2002) (15)
Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium. (2021) (15)
Biological and clinical features of acute lymphoblastic leukaemia with cytoplasmic granules or inclusions: description of eight cases (1989) (15)
Rearrangements of the RAR-alpha gene in acute promyelocytic leukaemia: correlations with morphology and immunophenotype. (1991) (15)
EVI-1 gene expression in myeloid clonogenic cells from juvenile myelomonocytic leukemia (JMML) (1997) (15)
An update on PCR use for minimal residual disease monitoring in acute lymphoblastic leukemia (2017) (15)
Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to “Incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute ly (2013) (15)
Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing (2021) (15)
Low prevalence of IDH1 gene mutation in childhood AML in Italy (2011) (15)
Neonatal cellular and gene therapies for mucopolysaccharidoses: the earlier the better? (2015) (15)
Location First: Targeting Acute Myeloid Leukemia Within Its Niche (2020) (15)
Adolescents with Cancer in Italy: Improving Access to National Cooperative Pediatric Oncology Group (AIEOP) Centers (2016) (14)
Peripheral blood progenitor cell collection in chronic myeloid leukemia patients with complete cytogenetic response after treatment with imatinib mesylate (2005) (14)
An Extensive Quality Control and Quality Assurance (QC/QA) Program Significantly Improves Inter-Laboratory Concordance Rates of Flow-Cytometric Minimal Residual Disease Assessment in Acute Lymphoblastic Leukemia: An I-BFM-FLOW-Network Report (2021) (14)
Polymerase chain reaction (PCR) approach for the evaluation of minimal residual disease in acute leukemia (1994) (14)
Human aplastic anaemia‐derived mesenchymal stromal cells form functional haematopoietic stem cell niche in vivo (2017) (14)
Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling. (2016) (14)
Redirecting T cells with Chimeric Antigen Receptor (CAR) for the treatment of childhood acute lymphoblastic leukemia. (2017) (14)
Impact of COVID-19 on the Pattern of Access to a Pediatric Emergency Department in the Lombardy Region, Italy. (2020) (14)
Immunoglobulin light chain kappa deletion rearrangement as a marker of clonality in mantle cell lymphoma. (1999) (14)
Droplet Digital PCR Improves IG-/TR-based MRD Risk Definition in Childhood B-cell Precursor Acute Lymphoblastic Leukemia (2021) (14)
Monitoring minimal residual disease using chromosomal translocations in childhood ALL. (2002) (14)
Establishment of human acute myelogenous leukemia lines secreting interleukin‐1β in SCID mice (1995) (14)
T-cell acute lymphoblastic leukemia occurring in a patient with acute promyelocytic leukemia. (1998) (14)
Randomized post-induction and delayed intensification therapy in high-risk pediatric acute lymphoblastic leukemia: long-term results of the international AIEOP-BFM ALL 2000 trial (2019) (14)
Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor (2018) (14)
Paediatric non‐Hodgkin lymphoma in low and middle income countries (2016) (14)
Multigenetic lesions in infant acute leukaemias: correlations with ALL‐1 gene status (1997) (14)
Molecular Monitoring of Minimal Residual Disease (2003) (13)
New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations (2021) (13)
Prevalence of Immunological Defects in a Cohort of 97 Rubinstein–Taybi Syndrome Patients (2020) (13)
Results of a multicenter universal newborn screening program for sickle cell disease in Italy: A call to action (2019) (13)
Early diagnosis of PI3Kδ syndrome in a 2 years old girl with recurrent otitis and enlarged spleen. (2017) (13)
Results of minimal residual disease (MRD) evaluation and MRD-based treatment stratification in childhood ALL. (2002) (13)
Prognostic value of minimal residual disease measured by flow-cytometry in two cohorts of infants with acute lymphoblastic leukemia treated according to either MLL-Baby or Interfant protocols (2020) (13)
Detailed stratified GWAS analysis for severe COVID-19 in four European populations (2022) (13)
Ataluren‐driven restoration of Shwachman‐Bodian‐Diamond syndrome protein function in Shwachman‐Diamond syndrome bone marrow cells (2018) (13)
Safe and Effective Treatment of Graft Versus Host Disease with Platelet Lysate-Expanded Mesenchymal Stromal Cells: A Prospective, Multicentric, Phase 1 Study (2013) (13)
Molecular genetics of the t(15;17) of acute promyelocytic leukemia (APPL). (1992) (13)
Philadelphia-Like Signature In Childhood Acute Lymphoblastic Leukemia: The AIEOP Experience (2013) (12)
Promoter analysis of TFPT (FB1), a molecular partner of TCF3 (E2A) in childhood acute lymphoblastic leukemia. (2001) (12)
Partial duplication of the PARK2 gene in a child with developmental delay and her normal mother: A second report (2013) (12)
Mesenchymal stromal cells from Shwachman‐Diamond syndrome patients fail to recreate a bone marrow niche in vivo and exhibit impaired angiogenesis (2018) (12)
Unbalanced t(3;12) in a case of juvenile myelomonocytic leukemia (JMML) results in partial trisomy of 3q as defined by FISH (1997) (12)
Molecular analysis of 1p32 genetic involvement in pediatric T-cell non-Hodgkin's lymphoma. (1999) (12)
Engineered T cells towards TNFRSF13C (BAFFR): a novel strategy to efficiently target B‐cell acute lymphoblastic leukaemia (2018) (12)
Isolation of monocytes from leukapheretic products for large‐scale GMP‐grade generation of cytomegalovirus‐specific T‐cell lines by means of an automated elutriation device (2008) (12)
Two siblings presenting with novel ADA2 variants, lymphoproliferation, persistence of large granular lymphocytes, and T-cell perturbations. (2020) (12)
Reconstitution of lymphocyte subpopulations in children with inherited metabolic storage diseases after haematopoietic cell transplantation (2005) (12)
GIMEMA-AIEOP AIDA Protocols for the Treatment of Newly Diagnosed Acute Promyelocytic Leukemia (APL) In Children: Analysis of 247 Patients Enrolled In Two Sequential Italian Multicenter Trials (2010) (12)
Abnormally expanded pro‐B hematogones associated with congenital cytomegalovirus infection (2007) (12)
Results of the AIEOP AML 2002/01 Study for Treatment of Children with Acute Myeloid Leukemia. (2009) (12)
CD34+ stem cell recovery after positive selection of "overloaded" immunomagnetic columns. (2005) (12)
Characterization of CD34+, CD13+, CD33- cells, a rare subset of immature human hematopoietic cells. (2002) (12)
Two cases of hepatic adenomas in patients with wolf‐hirschhorn syndrome: A new rare complication? (2013) (12)
Prenatal Origin of Pediatric Leukemia: Lessons From Hematopoietic Development (2021) (11)
Pharmacokinetic profile of imatinib mesylate and N-desmethyl-imatinib (CGP 74588) in children with newly diagnosed Ph+ acute leukemias (2009) (11)
Monitoring of minimal residual disease in leukemia, advantages and pitfalls (2006) (11)
Outcome of adolescent patients with acute lymphoblastic leukaemia aged 10-14 years as compared with those aged 15-17 years: Long-term results of 1094 patients of the AIEOP-BFM ALL 2000 study. (2019) (11)
PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias (2017) (11)
Reduced Intensity Delayed Intensification in Standard-Risk Patients Defined By Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Results of an International Randomized Trial in 1164 Patients (Trial AIEOP-BFM ALL 2000) (2016) (11)
A new case report of severe mucopolysaccharidosis type VII: diagnosis, treatment with haematopoietic cell transplantation and prenatal diagnosis in a second pregnancy (2018) (11)
Genotypes of the glutathione S-transferase superfamily do not correlate with outcome of childhood acute lymphoblastic leukemia (2003) (11)
Double target in situ hybridization applied to the study of numerical aberrations in childhood acute lymphoblastic leukemia. (1994) (11)
A European paediatric cancer mission: aspiration or reality? (2019) (10)
Potential use of CD40 ligand for immunotherapy of childhood B-cell precursor acute lymphoblastic leukaemia. (2004) (10)
Acute myeloid leukemia shapes the bone marrow stromal niche in vivo. (2020) (10)
PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients (2019) (10)
Identification of immunophenotypic signatures by clustering analysis in pediatric patients with Philadelphia chromosome‐positive acute lymphoblastic leukemia (2010) (10)
BCR-ABL1-like acute lymphoblastic leukemia in childhood and targeted therapy. (2020) (10)
Commitment of juvenile myelo-monocytic (JMML) leukemic cells to spontaneously differentiate into dendritic cells. (2002) (10)
Agranulocytosis due to deferiprone: a case report with cytomorphological and functional bone marrow examination. (2011) (10)
New advances in leukaemia immunotherapy by the use of Chimeric Artificial Antigen Receptors (CARs): state of the art and perspectives for the near future (2011) (10)
Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia (2021) (10)
Intermittent granulocyte maturation arrest, hypocellular bone marrow, and episodic normal neutrophil count can be associated with SRP54 mutations causing Shwachman–Diamond‐like syndrome (2020) (10)
Three novel fusion transcripts of the paired box 5 gene in B-cell precursor acute lymphoblastic leukemia (2015) (10)
The thirteenth international childhood acute lymphoblastic leukemia workshop report: La Jolla, CA, USA, December 7–9, 2011 (2013) (10)
Generic formulations of imatinib for treatment of Philadelphia chromosome–positive leukemia in pediatric patients (2018) (10)
An Attempt to Induce Transient Immunosuppression Pre-erythrocytapheresis in a Girl With Sickle Cell Disease, a History of Severe Delayed Hemolytic Transfusion Reactions and Need for Hip Prosthesis (2013) (9)
The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. (2008) (9)
The Effects of Propofol and Ketamine on the Cytokine Levels of Children With Acute Lymphoblastic Leukemia (2013) (9)
Impact of Minimal Residual Disease (MRD) on Prognosis in Children with Acute Lymphoblastic Leukemia (ALL) According to WBC Count, Age and TEL/AML1 Status at Diagnosis. Results of the AIEOP-BFM ALL 2000 Study. (2007) (9)
Cytogenetic and molecular characterization of T-cell acute lymphoblastic leukemia as a second tumor after anaplastic large-cell lymphoma in a boy. (1999) (9)
Case of congenital hypotransferrinemia suggests that tissue hypoxia during fetal development may cause hypospadias. (2000) (9)
Mesenchymal stromal cell-secreted chemerin is a novel immunomodulatory molecule driving the migration of ChemR23-expressing cells. (2017) (9)
Early Detection of Relapse by Prospective Reverse Transcriptase-Polymerase Chain Reaction Analysis of the PML / RAR a Fusion Gene in Patients With Acute Promyelocytic Leukemia (1998) (9)
Acute myeloid leukaemia niche regulates response to L‐asparaginase (2019) (9)
The Italian Registry for Primary Immunodeficiencies (Italian Primary Immunodeficiency Network; IPINet): Twenty Years of Experience (1999–2019) (2020) (9)
RECURRENT GENETIC FUSIONS REDEFINE MLL-GERMLINE ACUTE LYMPHOBLASTIC LEUKEMIA IN INFANTS. (2020) (9)
Single‐cell profiling of pediatric T‐cell acute lymphoblastic leukemia: Impact of PTEN exon 7 mutation on PI3K/Akt and JAK–STAT signaling pathways (2020) (9)
Development of advanced therapies in Italy: Management models and sustainability in six Italian cell factories. (2016) (9)
A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B-cell Acute Lymphoblastic Leukemia (2019) (9)
Association of gastric and Waldeyer's ring lymphoma: a molecular study (2000) (9)
Stem cells in severe infantile spinal muscular atrophy (SMA1) (2012) (9)
Targeting of Acute Myeloid Leukemia by Cytokine-Induced Killer Cells Redirected with a Novel CD123-Specific Chimeric Antigen Receptor. (2012) (9)
Cervical spine malformation in cornelia de lange syndrome: A report of three patients (2014) (8)
Lower-limb MRI in the staging and re-staging of osteonecrosis in paediatric patients affected by acute lymphoblastic leukaemia after therapy (2016) (8)
SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia (2018) (8)
The Past, Present, and Future of Non-Viral CAR T Cells (2022) (8)
Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice (2017) (8)
ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment (2021) (8)
TNFRSF13C (BAFFR) positive blasts persist after early treatment and at relapse in childhood B‐cell precursor acute lymphoblastic leukaemia (2018) (8)
First evidence of a paediatric patient with Cornelia de Lange syndrome with acute lymphoblastic leukaemia (2019) (8)
Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19 (2022) (8)
Validation of Minimal Residual Disease as Surrogate Endpoint for Event-Free Survival in Childhood Acute Lymphoblastic Leukemia (2018) (8)
ETV6-RUNX1 fusion gene and additional genetic changes in infant leukemia: a genome-wide analysis. (2009) (8)
The Experience of the International Registry for Chronic Myeloid Leukemia (CML) in Children and Adolescents (I-CML-Ped Study): Pronostic Consideration (2014) (8)
Cytoskeletal Regulatory Gene Expression and Migratory Properties of B-cell Progenitors Are Affected by the ETV6–RUNX1 Rearrangement (2014) (8)
Dissecting Proto-Oncogenic PIM Serine/Threonine Kinases in FLT3-ITD-Induced Leukemogenesis: PIM1 Regulates CXCL12/CXCR4-Mediated Homing and Migration (2008) (8)
Efficient detection of leukemia-related fusion transcripts by multiplex PCR applied on a microelectronic platform (2008) (8)
Erratum: Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia (2016) (8)
Neonatal umbilical cord blood transplantation halts skeletal disease progression in the murine model of MPS-I (2017) (8)
“There's no Reason why”: A Campaign to Raise Cancer Awareness among Adolescents (2016) (8)
Childhood cancer in Italy: background, goals, and achievements of the Italian Paediatric Hematology Oncology Association (AIEOP) (2021) (7)
Structure and rearrangement of the T cell receptor J alpha locus in T cells and leukemic T cell lines (1988) (7)
Advanced Phases at Diagnosis of Childhood Chronic Myeloid Leukemia : The Experience of the International Registry for Chronic Myeloid Leukemia (CML) in Children and Adolescents (I-CML-Ped Study) (2017) (7)
MODULATION OF NK ACTIVITY BY HUMAN MONONUCLEAR PHAGOCYTES: SUPPRESSIVE ACTIVITY OF BRONCHO-ALVEOLAR MACROPHAGES (1982) (7)
Neonatal combination therapy improves some of the clinical manifestations in the Mucopolysaccharidosis type I murine model. (2020) (7)
Low prevalence of IDH1 gene mutation in childhood AML in Italy. Leukemia. (2010) (7)
Lymphoblastic predominance of blastic phase in children with chronic myeloid leukaemia treated with imatinib: A report from the I-CML-Ped Study. (2020) (7)
Monocyte–macrophage polarization and recruitment pathways in the tumour microenvironment of B‐cell acute lymphoblastic leukaemia (2021) (7)
Efficacy and Safety of Imatinib on Top of BFM-Like Chemotherapy in Pediatric Patients with Ph+/BCR-ABL+ Acute Lymphoblastic Leukemia (Ph+ALL). the EsPhALL Study (2011) (7)
Novel clinical trials for pediatric leukemias: lessons learned from genomic analyses. (2013) (7)
Natural history of acute lymphoblastic leukemia in neurofibromatosis type 1 monozygotic twins (2013) (7)
A Phase 2 Study to Test the Feasibility, Safety and Efficacy of the Addition of Blinatumomab to the Interfant06 Backbone in Infants with Newly Diagnosed KMT2A-Rearranged Acute Lymphoblastic Leukemia. a Collaborative Study of the Interfant Network (2021) (7)
Hepatic Granulomatous Lesions Caused by Systemic Bartonella vinsonii subsp. arupensis Infection in a Child. (2015) (7)
Full GMP-Compliant Validation of Bone Marrow-Derived Human CD133+ Cells as Advanced Therapy Medicinal Product for Refractory Ischemic Cardiomyopathy (2015) (7)
Biological and clinical features of B-precursor childhood acute lymphoblastic leukemia showing CD2 and/or E-rosette co-expression. (1992) (7)
The new frame for Mucopolysaccharidoses (2018) (7)
Lessons After the Early Management of the COVID-19 Outbreak in a Pediatric Transplant and Hemato-Oncology Center Embedded within a COVID-19 Dedicated Hospital in Lombardia, Italy. Estote Parati. (Be Ready.) (2020) (7)
Autologous purified peripheral blood stem cell transplantation compare to chemotherapy in childhood acute lymphoblastic leukemia after low‐risk relapse (2011) (6)
Williams syndrome and mature B-Leukemia: A random association? (2016) (6)
Genomic analysis of different clonal evolution in a twin pair with t(12;21) positive acute lymphoblastic leukemia sharing the same prenatal clone (2008) (6)
Lenalidomide enhances CD23.CAR T cell therapy in chronic lymphocytic leukemia (2022) (6)
Transcriptional and post-transcriptional regulation of IL-1 beta, IL-6 and TNF-alpha genes in chronic lymphocytic leukaemia. (1993) (6)
A boy with Burkitt lymphoma associated with Noonan syndrome due to a mutation in RAF1 (2013) (6)
Simultaneous occurrence of acute myeloid leukaemia with mutated nucleophosmin (NPM1) in the same family (2009) (6)
Outcome of Infants Younger Than 1 Year with Acute Lymphoblastic Leukemia Treated with the Interfant-06 Protocol; Results from an International Randomised Study (2018) (6)
Expression and modulation of a mononuclear phagocyte differentiation antigen (PAM-1) during in vitro maturation of peripheral blood monocytes (1993) (6)
The Biology of Acute Lymphoblastic Leukemia (2011) (6)
INTERNATIONAL COLLABORATIVE TREATMENT PROTOCOL FOR INFANTS UNDER ONE YEAR WITH ACUTE LYMPHOBLASTIC OR BIPHENOTYPIC LEUKEMIA (2015) (6)
Activin A contributes to the definition of a pro-oncogenic bone marrow microenvironment in t(12;21) preleukemia. (2019) (6)
Detection of the breakpoint cluster region-ABL fusion in chronic myeloid leukemia with variant Philadelphia chromosome translocations by in situ hybridization. (1996) (6)
Successful Application of OPLS‐DA for the Discrimination of Wild‐Type and Mutated Cells in Acute Lymphoblastic Leukemia (2009) (6)
Rings and Bricks: Expression of Cohesin Components is Dynamic during Development and Adult Life (2018) (6)
EARLY T-CELL PRECURSOR LEUKEMIA: A SUBTYPE OF VERY HIGH-RISK ACUTE LYMPHOBLASTIC LEUKEMIA IDENTIFIED IN TWO INDEPENDENT COHORTS (2010) (6)
Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation (2016) (6)
Results of the AIEOP-BFM ALL 2000 Study for Childhood Acute Lymphoblastic Leukemia IN AIEOP High Risk Patients. (2009) (6)
Understanding the Immunomodulatory Effect of Mesenchymal Stem Cell Infused In Transplanted Patients with Steroid-Refractory GvHD (2010) (6)
PCR Technology to Identify Minimal Residual Disease. (2021) (6)
Assessment of submicroscopic genetic lesions by single nucleotide polymorphism arrays in a child with acute myeloid leukemia and FLT3-internal tandem duplication. (2006) (6)
Evaluation of the Pattern of Use of a Pediatric Emergency Department in Italy (2020) (6)
Lineage switch in a childhood T-cell acute lymphoblastic leukemia. (1992) (6)
Minimal residual disease and outcome characteristics in infant KMT2A-germline acute lymphoblastic leukaemia treated on the Interfant-06 protocol (2021) (6)
Infusion of Donor Derived Cytokine Induced Killer Cells May Induce Clinical Remission with Limited GVHD in Patients Relapsing after Allogeneic Stem Cell Transplantation. (2006) (6)
Loss of CBL E3‐ligase activity in B‐lineage childhood acute lymphoblastic leukaemia (2012) (6)
Results and outcome of intermittent imatinib (ON/OFF schedule) in children and adolescents with chronic myeloid leukaemia (2020) (6)
Thrombocytopenia and Cornelia de Lange syndrome: Still an enigma? (2016) (6)
Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects (2020) (6)
The Strong Prognostic Effect of Concurrent Deletions of IKZF1 and PAX5, CDKN2A, CDKN2B or PAR1 in the Absence of ERG Deletions (IKZF1plus) in Pediatric Acute Lymphoblastic Leukemia Strongly Depends on Minimal Residual Disease Burden after Induction Treatment (2014) (6)
Chromosome-Positive ( Ph 1 ) Childhood Acute Lymphoblastic Leukemia : Good Initial Steroid Response Allows Early Prediction of a Favorable Treatment Outcome (1998) (6)
Incidence of Hypersensitivity Reactions (HSR) Reactions (HSR) to Peg-Asparaginase (PEG-ASP) in 6136 Patients Treated in the AIEOP-BFM ALL 2009 Study Protocol (2019) (5)
Unraveling the Efficacy and Safety Profiles of Anti-CD123 Chimeric Antigen Receptors (CARs) in a Model of Acute Myeloid Leukemia Immunotherapy By Investigating CAR Binding Affinity and Density Variables (2015) (5)
Impairment of Retinoic Acid Signaling in Cornelia de Lange Syndrome Fibroblasts. (2017) (5)
Pharmacodynamic effects in the cerebrospinal fluid of rats after intravenous administration of different asparaginase formulations (2017) (5)
Advanced Targeted, Cell and Gene-Therapy Approaches for Pediatric Hematological Malignancies: Results and Future Perspectives (2013) (5)
Genomic Imbalances Are Confined to Non-Proliferating Cells in Paediatric Patients with Acute Myeloid Leukaemia and a Normal or Incomplete Karyotype (2011) (5)
Collaboration between Activating Mutations in JAK2 and Trisomy 21 in the Acute Lymphoblastic Leukemias of Down Syndrome (DS). (2007) (5)
Safe and Effective Treatment of Graft Versus Host Disease with Platelet Lysate-Expanded Human Mesenchymal Stromal Cells: A Phase 1 Study On 47 Adult and Pediatric Patients (2012) (5)
Primary immunodeficiencies, autoimmune hyperthyroidism, coeliac disease and systemic lupus erythematosus in childhood immune thrombocytopenia (2020) (5)
From bone marrow transplantation to cellular therapies: possible therapeutic strategies in managing autoimmune disorders. (2012) (5)
Final Analysis of a Multicenter Pilot Phase 2 Study of Cytokine Induced Killer (CIK) Cells for Patients with Relapse after Allogeneic Transplantation (2016) (5)
Oral Nutritional Supplementation in Children Treated for Cancer in Low− and Middle-Income Countries Is Feasible and Effective: the Experience of the Children’s Hospital Manuel De Jesus Rivera “La Mascota” in Nicaragua (2018) (5)
Characterization of migratory activity and cytokine profile of helper and cytotoxic CMV-specific T-cell lines expanded by a selective peptide library. (2008) (5)
Diagnosis and monitoring of PML-RARA-positive acute promyelocytic leukemia by qualitative RT-PCR. (2006) (5)
Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19 (2022) (5)
A new report of Cornelia de Lange syndrome associated with split hand and feet (2012) (5)
Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19 (2022) (4)
Hodgkin lymphoma in a patient with mosaic trisomy 18: First clinical observation (2016) (4)
Program an Anti-Inflammatory Immunosuppressive Monocyte-Derived Dendritic Cells Activates Cross-Linking of the Mannose Receptor on Mantovani (2003) (4)
Identification of DNA Rearrangements at the Retinoic Acid Receptor-a ( RARa ) Locus in All Patients With Acute Promyelocytic Leukemia ( APL ) and Mapping of APL Breakpoints Within the RARa Second Intron (2003) (4)
Early evaluation of bone marrow minimal residual disease by flowcytometry on day 15 is feasible on a multicenter basis and bears strong prognostic value in childhood acute lymphoblastic leukemia. The AIEOP-BFM experience (2007) (4)
Musculoskeletal manifestations of childhood cancer and differential diagnosis with juvenile idiopathic arthritis (ONCOREUM): a multicentre, cross-sectional study (2021) (4)
Multi-omics approach identifies novel age-, time- and treatment-related immunopathological signatures in MIS-C and pediatric COVID-19 (2021) (4)
Clonal hematopoiesis is not significantly associated with COVID-19 disease severity (2022) (4)
Early response does not predict outcome in children and adolescents with chronic myeloid leukaemia treated with high‐dose imatinib (2018) (4)
TEL/ARG induces cytoskeletal abnormalities in 293T cells. (2006) (4)
Digital-Droplet PCR, an Accurate Method for IG/TR PCR-MRD Stratification in Childhood Acute Lymphoblastic Leukemia (2018) (4)
Prognostic Value of Minimal Residual Disease Measured By Flow Cytometry in Two Cohorts of Infants with Acute Lymphoblastic Leukemia Treated with MLL-Baby and Interfant Protocols in Large Multicenter Networks (2019) (4)
The Role of PAX5 in ALL (2011) (4)
Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic Leukemia (B-ALL) (2019) (4)
Time Point-Dependent Concordance of Flow Cytometry and RQ-PCR in the MRD Detection in Childhood ALL: The Experience of the AIEOP-BFM- ALL MRD Study Group (2008) (4)
From Adjustment to Thriving: Exploring Well-Being in Young Adult Survivors of Childhood Cancer and Their Siblings. (2016) (4)
Tailoring treatment strategy for acute promyelocytic leukemia in low‐income countries (2009) (4)
Acute Lymphoblastic Leukaemia Cells Carrying the t(12;21) Translocation Are Highly Sensitive to Alemtuzumab Mediated Cell Lysis. (2005) (4)
A Girl with Life Threatening Meningitis Caused by an Infected Dermoid Cyst Derived from an Occult Dermal Sinus (2014) (4)
Children with TEL/AML1-Positive Acute Lymphoblastic Leukemia (ALL) and Favorable Presenting Features May Benefit from the Use of Vincristine-Dexamethasone (VCR-DXM) Pulses on Top of Antimetabolite-Based Continuation Therapy. (2005) (4)
Real-Life Management of Children and Adolescents with Chronic Myeloid Leukemia: The Italian Experience (2018) (4)
Neutropenia, hypogammaglobulinemia, and pneumonia: A case of WHIM syndrome (2018) (3)
A novel EP300 mutation associated with Rubinstein‐Taybi syndrome type 2 presenting as combined immunodeficiency (2018) (3)
Clonal Evolution and Lack of BCR-ABL1 Mutations in Pediatric Ph+ ALL Patients Resistant/Refractory to Imatinib Treatment (2015) (3)
When to suspect GATA2 deficiency in pediatric patients: from complete blood count to diagnosis (2021) (3)
Cytotoxicity and DNA damage caused by 4-demethoxydaunorubicin and its metabolite 4-demethoxy-13-hydroxydaunorubicin in human acute myeloid leukemia cells (2008) (3)
Outcome of Early T-Cell Precursor Acute Lymphoblastic Leukemia in AIEOP Patients Treated with the AIEOP-BFM ALL 2000 Study (2014) (3)
Long pentraxin 3 (PTX3) levels predict death, intubation and thrombotic events among hospitalized patients with COVID-19 (2022) (3)
Switch to Subsequent Line of Treatment in Children and Adolescents with Chronic Myeloid Leukemia (CML) Treated with Imatinib: Experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents (I-CML-Ped Study) (2015) (3)
Generation of a New Chimeric Antigen Receptor (CAR) to Target CD23 Expressed on Chronic Lymphocytic Leukemia (B-CLL) Cells (2008) (3)
Precursor B‐cell acute lymphoblastic leukaemia—a global view (2021) (3)
Description and Management of Accelerated Phase and Blast Crisis in 21 CML Pediatric Patients (2015) (3)
Cytokine-induced killer (CIK) cells engineered with chimeric antigen receptors (CARs) by sleeping beauty system (2014) (3)
Therapy-related acute leukemia associated with involvement of 11q23 after high grade non-Hodgkin lymphoma. (1998) (3)
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 (2023) (3)
A Multicenter Phase II Study of Sequential Administration of Unmanipulated DLI and Donor Derived Cytokine Induced Killer (CIK) Cells in HSCT Patients, Relapsed of Disease (2015) (3)
Balance of Anti-CD123 Chimeric Antigen Receptor (CAR) Binding Affinity and Density for the Treatment of Acute Myeloid Leukemia (2016) (2)
Combining the Expression of CD33.CAR and CXCR4 to Increase CAR-CIK Cell Homing to Bone Marrow Niche and Leukemic Stem Cell Eradication in Acute Myeloid Leukemia (2021) (2)
Regulation of the Tumoricidal and Suppressive Activity of Human Macrophages (1983) (2)
ACUTE LYMPHOBLASTIC LEUKAEMIA WITH CYTOPLASMIC GRANULES OR INCLUSIONS (1990) (2)
Evaluation of Technical Issues in a Pilot Multicenter Newborn Screening Program for Sickle Cell Disease (2018) (2)
High Dose Methotrexate (HD MTX at 2 gr/sqm x 4) Associated to Extended Intrathecal (IT) Chemotherapy Is Effective for Prevention of Central Nervous System (CNS) Relapse in Childhood ALL Treated with BFM Systemic Therapy. (2005) (2)
Characterization of CD 34 + , CD 13 + , CD 33 — cells , a rare subset of immature human hematopoietic cells (2002) (2)
“Growth patterns in children with mucopolysaccharidosis type I-Hurler after hematopoietic stem cell transplantation: Comparison with untreated patients” (2021) (2)
Germline mosaicism in cornelia de lange syndrome: Dilemmas and risk figures (2013) (2)
PAX5/TEL Has An Opposite Dominant Effect on Endogenous PAX5, Affecting Its Transcriptional Regulation, B Cell Adhesion and BCR Signaling In Murine Pre-BI Cells (2010) (2)
The Chemerin/ChemR23 Axis Plays a Pivotal Role in the Pathogenesis of Intestinal Damage in a Murine Model of Graft Versus Host Disease (2015) (2)
Highly Sensitive Mutations Detection in BCR-ABL Positive Leukemia Prior and during Imatinib Treatment. (2004) (2)
Maturation signatures of conventional dendritic cells in COVID-19 reflect direct viral sensing (2021) (2)
Failure of interferon-γ pretreated mesenchymal stem cell treatment in a patient with crohn ’ s disease (2015) (2)
Dexamethasone Stimulation Test in the Diagnostic Work-Up of Growth Hormone Deficiency in Childhood: Clinical Value and Comparison With Insulin-Induced Hypoglycemia (2020) (2)
CD123 and CD33 Co-Targeting By Balanced Signaling on CAR-CIK Cells Reduces Potential Off-Target Toxicity While Preserving the Anti-Leukemic Activity of Acute Myeloid Leukemia (2021) (2)
International Laboratory Comparison of Methodologies for Determining Minimal Residual Disease (MRD) in Childhood Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) (2015) (2)
Heterogeneity of the bone marrow niche in patients with myeloproliferative neoplasms: ActivinA secretion by mesenchymal stromal cells correlates with the degree of marrow fibrosis (2020) (2)
ImmunoTyper-SR: A Novel Computational Approach for Genotyping Immunoglobulin Heavy Chain Variable Genes using Short Read Data (2022) (2)
Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells (2021) (2)
High EVI1 Expression due to NRIP1/EVI1 Fusion in Therapy-related Acute Myeloid Leukemia: Description of the First Pediatric Case (2020) (2)
Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL. (2017) (2)
More than an ‘atypical’ phenotype: dual molecular diagnosis of autoimmune lymphoproliferative syndrome and Becker muscular dystrophy (2020) (2)
How to Confront the Problem of Treatment of Childhood Leukemias in Underprivileged Populations (2003) (2)
A Treatment Protocol with Imatinib and Intensive Chemotherapy for Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia: A Single-Arm, Intergroup Study (Esphall 2010) (2018) (2)
Treatment Intensification of Traditional BFM Therapy with 3 Chemotherapy Blocks and Double Delayed Intensification (Protocol II) Improves Outcome in Infants with High Risk (HR) Acute Lymphoblastic Leukemia (ALL): Results of Two Consecutive AIEOP Studies. (2005) (2)
The Impact of a Precision-Based Exercise Intervention in Childhood Hematological Malignancies Evaluated by an Adapted Yo-Yo Intermittent Recovery Test (2022) (2)
Cytokine release syndrome after CAR infusion in pediatric patients with refractory/relapsed B-ALL: is there a role for diclofenac? (2021) (1)
Structural Variations Identified By Whole Transcriptome Sequencing (RNA-Seq) in Childhood ALL with Different Response to Therapy (2014) (1)
CD14 positive cells accelerate hematopoietic stem cell engraftment (2022) (1)
C ombined MV-trans Retinoic Acid and Idarubicin (AIDA) Therapy (1997) (1)
Poor Prognosis for IKZF1 Intra-Gene Deletions in Pediatric Ph– B-Cell Precursor Acute Lymphoblastic Leukemia (2011) (1)
markers and preferential cardiovascular commitment (2010) (1)
Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia (2015) (1)
Molecular Biological Detection of Minimal Residual Disease in Acute Myeloid Leukemia (1997) (1)
Serum anti-Müllerian hormone as a marker of ovarian reserve after cancer treatment and/or hematopoietic stem cell transplantation in childhood: proposal for a systematic approach to gonadal assessment. (2021) (1)
Comparison of Dfferent Suicide Gene Strategies for the Safety Improvement of Genetically Manipulated T Cells. (2010) (1)
Donor-Derived CAR T Cells Engineered with Sleeping Beauty Achieve Anti-Leukemic Activity without Severe Toxicity (2020) (1)
Analysis of the PML/RAR-α Fusion Gene in Acute Promyelocytic Leukemia by Reverse-Transcription Polymerase Chain Reaction : Technical Recommendations, Advantages, and Pitfalls. (1996) (1)
Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL) (2018) (1)
Minimal residual disease in BCR::ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease (2022) (1)
Osteopathic Treatment and Evaluation in the Clinical Setting of Childhood Hematological Malignancies (2021) (1)
Specific Targeting of Acute Myeloid Leukemia By the Use of Non-Virally Engineered CIK (Cytokine-Induced Killer) Cells Expressing the Anti-CD33 Chimeric Antigen Receptor (CAR) (2018) (1)
In Infant ALL with t(4;11)/ MLL-AF4 multiple and phenotypically distinct CD19+ BM subsets initiate leukemia in NOD/SCID mice (2010) (1)
Prognostic discrimination of children and adolescents with chronic myeloid leukemia based on the EUTOS Long Term Survival (ELTS) score (2016) (1)
On the differentiative mode of action of All-trans retinoic acid in acute promyelocytic leukemia. (1995) (1)
Germ-Line TP53 Mutation in an Adolescent With CMML/Atypical CML and Familiar Cancer Predisposition (2020) (1)
Activin A, a Potential Key Factor of the Malignant Bone Marrow Niche, Enhances B-Cell Precursor-Acute Lymphoblastic Leukemic Cell Migratory and Invasive Properties (2018) (1)
Impact of Minimal Residual Disease (MRD) on Prognosis in Children with Philadelphia Positive Acute Lymphoblastic Leukemia (ALL) Treated in the AIEOP-BFM ALL 2000 Study. (2008) (1)
Fludarabine as a cost-effective adjuvant to enhance engraftment of human normal and malignant hematopoiesis in immunodeficient mice (2018) (1)
Children and coronavirus: The necessary search for a balance between the alleged risks and documented collateral damage (2020) (1)
Biological Features and Prognostic Impact of CRLF2 Overexpression In Childhood ALL (2010) (1)
A novel homozygous disruptive PRF1 variant (K285Sfs*4) causes very early-onset of familial hemophagocytic lymphohystiocytosis type 2 (2020) (1)
Impact of Additional Cytogenetic Abnormalities and Variant t(9;22) at Diagnosis on Prognosis of Childhood Chronic Myelogenous Leukemia : The Experience of the International Registry for CML in Children and Adolescents (I-CML-Ped Study) (2014) (1)
XVI International Workshop on Chronic Lymphocytic Leukemia 2015 6–9 September 2015 Sydney, Australia (2015) (1)
Case Report: Hypomorphic Function and Somatic Reversion in DOCK8 Deficiency in One Patient With Two Novel Variants and Sclerosing Cholangitis (2021) (1)
[SENTIERI KIDS: protecting health and preventing childhood cancer in contaminated sites]. (2013) (1)
Detection of CALM-AF10 Fusion Transcript Does Not Predict A Poor Prognosis in Children with T-Lineage Acute Lymphoblastic Leukemia Treated with AIEOP ALL 2000 Protocol and Subsequent Modified 2000 Study (R-2006). (2009) (1)
Inhibition of GM-CSF prevents dissemination and induces remission of human juvenile myelomonocytic leukemia in engrafted immunodeficient mice. (1997) (1)
Evidence of treatment benefits in patients with MPSI-Hurler in long-term follow up using a new MRI scoring system. (2021) (1)
A Childhood Leukaemia Cluster in Milan: Possible Role of Pandemic AH1N1 Swine Flu Virus. (2012) (1)
Combining CD23 chimeric antigen receptor immunotherapy and lenalidomide as a novel therapeutic strategy for chronic lymphocytic leukemia (2014) (1)
Final Results of Phase I/II Study of Donor-Derived CAR T Cells Engineered with Sleeping Beauty in Pediatric and Adult Patients with B-Cell Acute Lymphoblastic Leukemia Relapsed Post-HSCT (2022) (1)
Intermittent Imatinib Mesylate in Children with Chronic Myeloid Leukemia: Results and Outcome (2018) (1)
Mutations of the PML tumor suppressor gene in APL (2003) (1)
Abstract 466: Valproic Acid Enhances Human Cord Blood CD34+ Cell Differentiation Toward The Endothelial Phenotype (2007) (1)
TEL/AML1 Rearrangement Is Rare in Children with Acute Lymphoblastic Leukemia (ALL) and Down Syndrome (DS). Presenting Features and Treatment Outcome in the Experience of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP). (2007) (1)
Sleeping Beauty Modified CAR+ Lymphocytes Engraft and Exhibit Anti-Tumor Activity in Patient-Derived Xenograft Models of Acute Lymphoblastic Leukemia (2016) (1)
PTPN11 and RAS Gene Mutation Pattern Identifies an Unique Feature of Upregulated RAS Function in Infant ALL. (2004) (1)
Novel Chimeric Transcripts Involving PAX5 in B-Cell Precursor ALL (2013) (1)
Pre-Clinical Efficacy of the Novel Kinase Inhibitor Nintedanib on PAX5 Fusion Genes in Pediatric Ph-like B-Cell Precursor Acute Lymphoblastic Leukemia (2019) (1)
Interleukin-17-Producing T Cells: A New Potential Player Mediating Graft Versus Host Pathology In Patients Undergoing Allogeneic Stem Cell Transplantion (2008) (1)
Role of CXCR 4-mediated bone marrow colonization in CNS infiltration by T-cell acute lymphoblastic leukemia (2016) (1)
FLT3-ITD As a Target for Minimal Residual Disease Monitoring in Early T-Cell Precursor (ETP) Acute Lymphoblastic Leukemia (2014) (1)
Globalization of pediatric research: pharmacological RCTs in Latin America (2019) (1)
Potential role of STAG1 mutations in genetic predisposition to childhood hematological malignancies (2022) (1)
Targeting of acute myeloid leukemia (AML) by cytokine-induced killer (CIK) cells redirected with a novel CD123-specific chimeric antigen receptor (CAR) (2013) (1)
CYTOKINE INDUCED KILLER (CIK) CELLS FOR CELL THERAPY OF ACUTE MYELOID LEUKEMIA (AML): IMPROVEMENT OF IMMUNE ACTIVITY BY EXPRESSION OF CD33-SPECIFIC CHIMERIC RECEPTORS (CAR) (2010) (1)
Human Mesenchymal Stroma Cells (hMSCs) Expanded with Human Platelets Lysate Are Safe and Effective For the Treatment of Graft Versus Host Disease (2008) (1)
High Clonal Evolution Rate in Relapsing Infant ALL Patients. (2004) (1)
A Versatile DNA/RNA NGS Targeted Capture Strategy for Detection of Fusion Genes in Pediatric ALL (2016) (1)
FLT3-ITD in Children with Early T-cell Precursor (ETP) Acute Lymphoblastic Leukemia: Incidence and Potential Target for Monitoring Minimal Residual Disease (MRD) (2022) (1)
Acute promyelocytic leukemia with unusual morphological features, absence of the t(15,17) and rearranged PML/RAR alpha genes. (1994) (1)
Severe and recurrent infections identify severe congenital neutropenia and primary immunodeficiencies in pediatric isolated neutropenia. (2020) (1)
Infant ALL patients carrying t(4;11) have a different genotypic profile than older ALL children (2007) (1)
Abnormal B-Cell Maturation and Increased Transitional B Cells in CBL Syndrome (2022) (1)
Somatic PTPN11 mutations in childhood acute leukemia (2004) (1)
Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases: A Report From the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Geno (2011) (0)
Abstract 1783: UMG1, a novel humanized monoclonal antibody against a glysosylated-CD43-related epitope, induces antibody-dependent cellular cytotoxicity (ADCC) on human T-cell acute lymphoblastic leukemia cells (2018) (0)
FUNCTIONAL STATUS OF TUMOR-ASSOCIATED EFFECTOR CELLS (1982) (0)
Angio-Phenotype of Pediatric Acute Lymphoblastic Leukemia and Pharmacodynamic Evaluation of the Antiangiogenic Activity of Corticosteroids. (2006) (0)
PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression (2013) (0)
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Therapy of Molecular Relapse in Acute Promyelocytic Leukemia (2016) (0)
Monozygotic Twins with Childhood ALL Demonstrate Prenatal Origin of the Philadelphia Chromosome and Post-Natal Ikaros Deletion. (2009) (0)
PAX5/TEL Causes Down Modulation of B-Lineage Specific Genes, and Enhances Migration to CXCL12 in preBI Cells. (2007) (0)
Clinico-Biologic Characterization of 5203 Acute Lymphoblastic Leukemia Patients Enrolled in the Italian Aieop and Gimema Protocols, Stratified in Age-Cohorts From Small Children to Young Elderly (2010) (0)
Novel Drugs to Target JAK2 Rearrangements in Pediatric Acute Lymphoblastic Leukemia (2022) (0)
Stable Expression of Chimeric Antigen Receptors by Sleep- ing Beauty Transposon System and Efficient Expansion of Leukemia-Specific Cytotoxic Cells (2014) (0)
Pentraxin-3: An Easily Measurable Soluble Factor to Improve Post-Transplant Graft Versus Host Disease Monitoring and Management. (2009) (0)
Quantitative Detection of NPM1 Mutations as Marker of Minimal Residual Disease (MRD) in the Large Majority of AML with Normal Karyotype. (2005) (0)
Acute Promyelocytic Leukaemia (2010) (0)
Comparison of MRD Monitoring By IG/TR Rearrangement and BCR/ABL1 Transcript in Ph+ Pediatric Acute Lymphoblastic Leukemia Patients Treated with Imatinib in the Esphall Study (2014) (0)
acute lymphoblastic leukemia Novel activating mutations lacking cysteine in type I cytokine receptors in (2014) (0)
STAT5 Phosphorylation Status by Flow Cytometry Is a Rapid and Reliable Tool for Diagnosis and Follow up of Juvenile Myelomonocytic Leukemia (2010) (0)
Heterozygous Mutation in Adenosine Deaminase Gene in a Patient With Severe Lymphopenia Following Corticosteroid Treatment of Autoimmune Hemolytic Anemia (2018) (0)
Skip pattern approach toward the early access of innovative anticancer drugs (2021) (0)
10 The Role of PAX 5 in ALL (2017) (0)
Impact of Donor and Patient CMV Serology in Children Receiving First Geno-Identical or Unrelated HSCT for Malignant Hematological Disease: An EBMT Retrospective Registry Study (2022) (0)
High Dose Imatinib Is Effective In Children and Adolescents With Chronic Myelogenous Leukemia In Chronic Phase. The Italian Experience (2013) (0)
3159 – PH-LIKE AND IKZF1PLUS FEATURES IN CHILDREN WITH DOWN SYNDROME ACUTE LYMPHOBLASTIC LEUKAEMIA (2022) (0)
Dominant-Negative Impact of PAX5/TEL on Downstream Targets of PAX5 and Essential Pre-B Cell Receptor Genes (2010) (0)
Prevalence of Immunological Defects in a Cohort of 97 Rubinstein–Taybi Syndrome Patients (2020) (0)
Activina: A Key Factor Mediating Chemoresistance in B-Cell Type Acute Lymphoblastic Leukemia (2022) (0)
PAX5/TEL Exhibits a Dominant-Negative Role by Inhibiting the Expression of Genes Involved in BCR Signalling and Suppressing the Binding of Wild Type PAX5 to Its Direct Target Gene CD79A (mb-1) in a human Pre-B ALL Cell Line. (2009) (0)
inhibition acute lymphoblastic leukemia, and its reversal by histone deacetylase in glucocorticoid poor-responsive pediatric BIM Epigenetic silencing of (2012) (0)
Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) (2015) (0)
childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study Late MRD response determines relapse risk overall and in subsets of (2013) (0)
3031 – MSI2 PLAYS A ROLE IN GLUCOCORTICOIDS RESISTANCE OF MLL-REARRANGED ALL BY REGULATING THE ENERGY METABOLISM OF LEUKEMIC CELLS (2022) (0)
Osteonecrosis in paediatric acute lymphoblastic leukaemia: Incidence, risk factors, radiological patterns and evolution in a single‐centre cohort (2022) (0)
Prevalence and Prognostic Impact of CEBPA mutations in Children with AML Treated with the AIEOP-LAM 2002/01 Protocol. (2009) (0)
P616: Cell-based noninvasive prenatal screening for a comprehensive fetal genome profiling for pathogenic submicroscopic CNVs in circulating trophoblasts from maternal blood (2023) (0)
Genomics Cytoskeletal Regulatory Gene Expression and Migratory Properties of B-cell Progenitors Are Affected by the ETV 6 – RUNX 1 Rearrangement (2014) (0)
PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120 (2022) (0)
Generation of Cytomegalovirus (CMV)-Specific CD4 and CD8 T Cell Lines Using Protein-Spanning Pools of pp65 and IE1 Derived Peptides. (2005) (0)
Collaboration of the Meningioma 1 (MN1) Oncogene with MLL-Fusions in Pediatric Leukemia (2008) (0)
Single-Cell Profiling of Signal Transduction Pathways in Pediatric T-Cell Acute Lymphoblastic Leukemia By Mass Cytometry:Dissecting JAK/STAT and PI3K/Akt/mTOR Active Signalling (2020) (0)
Phase II Study of Sequential Infusion of DLI and Cytokine Induced Killer Cells for Patients Relapsed after Sequential for (2017) (0)
BCR::ABL1-Positive Acute Lymphoblastic Leukemia: Different Clinical Behavior and Relevance of Prognostic Features in Typical ALL and in CML-like Disease (2022) (0)
Therapy-related acute leukemia associated with involvement of 11 q 23 after high grade non-Hodgkin lymphoma (2005) (0)
Oligoclonal Origin Of Functionally Distinct Leukemic Stem Cells In Infant Acute Lymphoblastic Leukemia (2010) (0)
Isolation and Characterization of Mesenchymal Stromal Cells Derived from Paediatric Patients with B Acute Lymphoblastic Leukemia (2015) (0)
Abstract 610: Evolutionary Conservation of Human CD34+ Cell Endothelial Differentiation in the Zebrafish Embryo (2007) (0)
PAX5/TEL Causes down Regulation of CD19 and TGFbeta Resistance in PreBI Cells. (2006) (0)
treatment of children with acute myeloid leukemia Results of the AIEOP AML 2002/01 multicenter prospective trial for the (2013) (0)
Increased Frequency of Cells with Activated Ribosomal Protein S6 at Diagnosis Associates with MRD Positivity and Relapse in Childhood BCP ALL (2015) (0)
Treatment of Philadelphia positive ( Ph + ) ALL and CML in children (2006) (0)
Identification Of Low Risk Group In Infants With Acute Lymphoblastic Leukemia By Flow Cytometric Minimal Residual Disease Measurement At Day 15 Of Interfant-99 and Interfant-06 Protocols Treatment (2013) (0)
Empagliflozin Modifies Neutrophils' Subsets in Patients with Glycogen Storage Disease Type Ib By Increasing Mature Neutrophils and Decreasing Immature Neutrophils (2022) (0)
Targeting JAK2 Gene Rearrangements with a Novel Kinase Inhibitor in a Preclinical Model of Pediatric Acute Lymphoblastic Leukemia (2021) (0)
Genomic and Transcriptomic Analyses Revealed Differences and Similarities Between T-Lbl and T-ALL. (2009) (0)
Management of Chronic Myeloid Leukemia in Children and Adolescents According to Local Guidelines.the Italian Experience (2016) (0)
Potential Role of STAG1 Mutations in Genetic Predisposition to Childhood Hemato-Oncological Diseases (2021) (0)
Poor Prognosis in Children with ABL-Class Fusion Positive B-Cell Acute Lymphoblastic Leukemia Treated According to AIEOP-BFM Protocols (2019) (0)
LONG TERM EFFICACY OF HUMAN BONE MARROW MESENCHYMAL STEM CELLS IN TRAUMATIZED MICE BRAIN IS NOT AFFECTED BY IMMUNOSUPPRESSIVE TREATMENT. (2012) (0)
PF436 GMP MANUFACTURING OF ALLOGENEIC CD19 CHIMERIC ANTIGEN RECEPTOR (CAR) CYTOKINE INDUCED KILLER (CIK) CELLS WITH SLEEPING BEAUTY (SB) TRANSPOSON FOR ADOPTIVE IMMUNOTHERAPY (2019) (0)
leukemia : results in 3184 patients of the AIEOP-BFM ALL 2000 study children and adolescents with B-cell precursor acute lymphoblastic Molecular response to treatment redefines all prognostic factors in (2010) (0)
PO-345 Long-Term Survivors of Childhood Acute Lymphoblastic Leukaemia (ALL):Does Parents’Emotional Well-being Aﬀect the Emotional Disposition of Their Survived Children? (2018) (0)
Overexpression of CXCR4 Enhances the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia (2022) (0)
Noonan Syndrome Peripheral Blood Cells Show Enhanced Spontaneous Colonies Growth In Vitro and Hyperactive JAK and RAS Intracellular Signalling Pathways (2013) (0)
Clinical-Grade Transduction of Allogeneic Cytokine Induced Killer (CIK) Cells with CD19 Chimeric Antigen Receptor (CAR) Using Sleeping Beauty (SB) Transposon: Successful GMP-Compliant Manufacturing for Clinical Applications (2018) (0)
The Migratory Activity of Anti-CD19 cTCR-Redirected CIK Cells as a Useful Property for In Vivo Targeting of B-ALL Cells. (2005) (0)
Constitutional Segmental Uniparental Disomy in a Twin Pair with t(12;21) Positive Acute Lymphoblastic Leukemia Characterized by the Same Prenatal Clone and Divergent Clonal Evolution. (2005) (0)
Hematopoietic stem cell transplant start-up in Iraqi Kurdistan: results on thalassemia patients and analysis of the methodology. (2023) (0)
ALL-167: A Phase 1/2 Study to Evaluate the Safety and Efficacy of Ponatinib with Chemotherapy in Pediatric Patients with Relapsed, Resistant, or Intolerant Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) or Have the T315I Mutation (2021) (0)
Cytokine Release Syndrome after Tisagenlecleucel Infusion in Pediatric Patients with Refractory/Relapsed B-Lineage Acute Lymphoblastic Leukemia: Is there a Role for Diclofenac? (2021) (0)
Study of Angiogenic Potential and Oxidative Metabolism in Mesenchymal Stromal Cells Derived from Shwachman-Diamond Syndrome Patients (2022) (0)
Neonatal umbilical cord blood transplantation halts skeletal disease progression in the murine model of MPS-I (2017) (0)
CI-FISH, GEP, and SNPs Correlate Genomic Categories with Risk Stratification in Children with T-ALL (2012) (0)
A Macromolecular Signaling Complex Formed by CXCR4, VLA4 and hERG1 K + Channels Mediates Bone Marrow-Induced Chemo-Resistance in Childhood Acute Lymphoblastic Leukemias: Shortcoming Effects of hERG1 Channels Inhibitors. (2008) (0)
Results of an AIEOP (Associazione Italiana di Ematologia e Oncologia Pediatrica) Randomized Clinical Trial in Children with Low- and Intermediate-Risk Relapsed Acute Lymphoblastic Leukemia (ALL) (2014) (0)
leukemia distinguishes cases with underlying A new morphologic classification system for acute promyelocytic (2000) (0)
Preclinical Assessment of Non-Virally Engineered CD33.CAR Cytokine-Induced Killer (CIK) Cells in Chemoresistant AML Patient-Derived Xenografts (2019) (0)
Low-Dose Lenalidomide Improves CAR-Based Immunotherapy In CLL By Reverting T-Cell Defects In Vivo (2013) (0)
Feasibility of Multicentric Assessment of MRD in All by Flow-Cytometry: Standardization and Experience of the I-BFM-ALL FCM-MRD Study Group. (2004) (0)
processcardiac properties through a cell fusion (2011) (0)
Glucocorticoid-Resistant B-Cell Acute Lymphoblastic Leukemic Cells Can be Targeted By BCR-Signaling Inhibition (2021) (0)
OP049: Automated isolation and genetic characterization of single circulating fetal trophoblasts in pregnant women (2022) (0)
Role of MRD Monitoring in Childhood Acute Lymphoblastic Leukemia after Allogeneic Transplantation. (2004) (0)
STUDYING THE ROLE OF PIM KINASES IN FLT3-ITD-INDUCED LEUKEMIA REVEALED PIM1 AS REGULATOR OF CXCL12/CXCR4-MEDIATED HOMING AND MIGRATION (2009) (0)
PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients (2019) (0)
ANALYSIS OF T-CELL RECEPTOR GENES CONFIGURATION IN MYCOSIS-FUNGOIDES (1992) (0)
PB1763: A PHASE 1/2 STUDY TO EVALUATE PONATINIB WITH CHEMOTHERAPY IN PEDIATRIC PATIENTS WITH RELAPSED/RESISTANT/INTOLERANT PHILADELPHIA CHROMOSOME–POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA OR WITH T315I MUTATION (2022) (0)
A Phase 1/2 Study to Evaluate the Safety and Efficacy of Ponatinib with Chemotherapy in Pediatric Patients with Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) (2020) (0)
Identification of chromosomal rearrangements in the human myeloid leukemia cell line GF‐D8 by dual‐colour fluorescence in situ hybridization (1995) (0)
MiR-125b Cooperates with BCR-ABL and Enhances Therapy Resistance in Childhood Ph+ ALL (2011) (0)
Use of anti-CD20 antibodies for the treatment of graft-versus-host disease (2000) (0)
leukemia Mutations of the PML tumor suppressor gene in acute promyelocytic (2013) (0)
First Description of a Frameshift PAX5 Germline Variant in Two Siblings with B-Cell Precursor Acute Lymphoblastic Leukemia (2022) (0)
Hypersensitivity Reactions to Native E. coli L-Asparaginase in Children with Acute Lymphoblastic Leukemia May Vary By Treatment Schedule and Type of Glucocorticoid in Induction: Results of Trial ALL-BFM 2000 (2022) (0)
Long-Term Outcome in Children and Adolescents with Chronic Myeloid Leukemia in Chronic Phase Treated with High-Dose Imatinib— the Italian Experience (2017) (0)
Promyelocytic Leukemia Genetic Diagnosis and Molecular Monitoring in the Management of Acute (2011) (0)
Immunomodulatory Interventions Based on Minimal Residual Disease before and after Transplantation for Childhood Acute Lymphoblastic Leukemia (2016) (0)
Running Title: T cell anergy induced by CD40L-activated BCP ALL cells. (2013) (0)
Identification of new genomic lesions in childhood ALL without known genetic aberrations: A microarray study of gene expression and genotype data. (2006) (0)
126. Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection and Vaccination (2021) (0)
and M3 variant) in childhood (letter) Diagnosis and incidence of acute promyelocytic leukemia (FAB M3 (2011) (0)
Flow Cytometric Measurement of the Initial In Vivo Response to Prednisone Provides New Prognostic Information in Childhood Acute Lymphoblastic Leukemia (ALL) (2018) (0)
A New in Vitro Model of Cortical Cerebral Organotypic Slices to Study Central Nervous System Microenvironment Modification By Leukemia Cells (2022) (0)
Legionellosi in Pediatria (2020) (0)
Abstract 2693: Relapse in BCP-ALL predicted by activated signaling in pro-B cell subsets (2016) (0)
NIPBL a new player with NPMc+ in the onset of acute myeloid leukemia (2018) (0)
NATURAL CYTOTOXICITY OF HUMAN MONONUCLEAR PHAGOCYTES: ROLE OF CONTAMINATING ENDOTOXIN AND EXPRESSION BY DIFFERENT MACROPHAGE POPULATIONS (1982) (0)
Evaluation of Minimal Residual Disease As a Surrogate Endpoint for Event Free Survival in Childhood B-Lineage Acute Lymphoblastic Leukemia (2016) (0)
P340: IN VITRO AND IN VIVO EFFICACY OF A NOVEL KINASE INHIBITOR TARGETING JAK2 GENE REARRANGEMENTS IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA (2022) (0)
IL3-zetakine combined with a CD33 costimulatory receptor as a Dual CAR approach for safer and selective targeting of AML. (2022) (0)
The RNA Binding Protein Musashi-2 (MSI2) Sustains the Growth and the Leukemogenic Potential of MLL-Rearranged Acute Lymphoblastic Leukemia, and It Is Involved in Glucocorticoid Resistance (2022) (0)
IRON OVERLOAD FOLLOWING HEMATOPOIETIC STEM CELL TRANSPLANTATION: PREVALENCE, SEVERITY AND MANAGEMENT IN CHILDREN AND ADOLESCENTS WITH MALIGNANT AND NON-MALIGNANT DISEASES. (2023) (0)
Anti-SARS-CoV-2 IgG antibodies induced by the BNT162b2 mRNA vaccine is age-dependent and influenced by a previous natural SARS-CoV-2 infection (2022) (0)
Chemerin As a New Potential Player in the Immunoregulatory Activity of Mesenchymal Stromal Cells (2014) (0)
Mechanism of Altered Nucleo-Cytoplasmic Traffic of Nucleophosmin in Acute Myelogenous Leukemia Carrying Exon-12 NPM Mutations (NPMc+ AML). (2005) (0)
ACUTE PROMYELOCYTIC LEUKEMIA WITH UNUSUAL MORPHOLOGICAL FEATURES , ABSENCE OF THE t ( 15 , 17 ) AND REARRANGED PML / RAR a GENES (2005) (0)
Interfant-99 protocol Outcome of congenital acute lymphoblastic leukemia treated on the (2013) (0)
leukemias with the t(4;11) translocation polymerase chain reaction for diagnosis and monitoring of acute Detection of ALL-1/AF4 fusion transcript by reverse transcription- (2011) (0)
Stable Expression Of Chimeric Antigen Receptors (CARs) By Sleeping Beauty-Mediated Gene Transfer and Efficient Expansion Of Leukemia-Specific Cytokine-Induced Killer (CIK) Cells (2013) (0)
Abstract 4867: Identification of an inv(16)-encodedCBFA2T3-GLIS2fusion protein in 34% of non-infant acute megkaryoblastic leukemias: A report from the Pediatric Cancer Genome Project (2012) (0)
Identical EP300 variant leading to Rubinstein–Taybi syndrome with different clinical and immunologic phenotype (2022) (0)
Clinical Manifestations of Lysosomal Acid Lipase Deficiency (LAL-D): The International LAL-D Registry (2020) (0)
Targeting Hyperactivated Lck in PAX5 Rearranged Pediatric B-Cell Precursors Acute Lymphoblastic Leukemia (2022) (0)
MRD analysis in mature B-ALL of childhood by I(G)GENE rearrangement and LD-PCR (2008) (0)
Tuned IL3-Zetakine Coupled to a CD33 Costimulatory Receptor As a Dual CAR for Safer and Selective Targeting of Acute Myeloid Leukemia (2022) (0)
Ph-like and IKZF1plus Features in Children with Down Syndrome and B Cell Precursor Acute Lymphoblastic Leukemia (2022) (0)
lymphomas: early analysis of the LY03 cooperative trial associated lymphoid tissue - Molecular follow-up in gastric mucosa (2013) (0)
Dissection of Submicroscopical Aberrations and Clonal Evolution from Birth To Diagnosis and Relapse in a Childhood AML FLT3-ITD Positive Patient by RQ-PCR and SNP Array Analyses. (2005) (0)
THE EUROPEAN ROADMAP TO HORIZON 2020 FOR CHILDREN AND ADOLESCENTS WITH CANCER - A LONG TERM SUSTAINABLE STRATEGY (2015) (0)
Clinical and Biological Characterization of Children with FLT3ITD Mutated Acute Myeloid Leukemia (AML): A Report from the AIEOP AML-2002 Study Group (2015) (0)
Thyroid function disorders and secondary cancer following haematopoietic stem cell transplantation in pediatrics: State of the art and practical recommendations for a risk-based follow-up (2022) (0)
LYMPHOID NEOPLASIA IKZF 1 status as a prognostic feature in BCR-ABL 1 – positive childhood ALL (2014) (0)
Multivariate Analysis Reveals a miRNA Profile Correlated To Karyotype and Outcome In Pediatric B-Cell Precursor ALL (2013) (0)
TEL-AML1 Affects the Regulation of Cytoskeleton and Causes Alteration In Cellular Adhesive and Migratory Properties In An In Vitro Model of Pre-Leukemia. (2010) (0)
Abstract 5425: Human CD34+ Cell Differentiation toward the Endothelial Lineage in the Zebrafish Embryo (2009) (0)
lymphoblastic leukemia: involvement of the chemokine CXCL10 Protumoral role of monocytes in human B-cell precursor acute (2012) (0)
Analysis of T Cell-Receptor Gene Configurations in Mycosis Fungoides (1994) (0)
Spirometry monitoring in asthmatic children in Lombardy Region, Italy (2018) (0)
acute lymphoblastic leukaemia + in monozygotic twins with Ph deletions IKZF1 fusion and BCR-ABL1 Developmental origins and impact of (2012) (0)
Purified Peripheral Autologous Stem Cell Transplant Versus Conventional Chemotherapy for Childhood Low Risk Relapsed Acute Lymphoblastic Leukemia. (2006) (0)
Sleeping beauty system-mediated expression of chimeric antigen receptors (CARs) in CIK cells: a novel tool towards the cure of childhood leukemia (2013) (0)
Euroflow-Based Immunophenotypic Characterization of CD34+ Cell Compartment in Juvenile Myelomonocytic Leukemia (JMML): A New Tool for Differential Diagnosis (2016) (0)
LONG TERM SURVIVAL AND EFFICACY OF HUMAN BONE MARROW MESENCHYMAL STEM CELLS IN TRAUMATIZED MICE BRAIN IS NOT DEPENDENT ON IMMUNOSUPPRESSIVE TREATMENT. (2012) (0)
Isolation of single circulating trophoblasts from maternal circulation for noninvasive fetal copy number variant profiling (2022) (0)
A New Chimeric Antigen Receptor (CAR) Targeting the CD23 Antigen Expressed by Chronic Lymphocytic Leukemia (B-CLL) Cells (2010) (0)
Homozygous Deletion in Stxbp2 Causative of Familial Hemophagocytic Lymphohistiocytosis Type 5 (Fhl-5) (2015) (0)
The Transition from Childhood to Adulthood in Chronic Immune Thrombocytopenia Patients: Clinical Management and the Role of Splenectomy and Thrombopoietin Receptor Agonists in a Single Center Experience (2018) (0)
Confers Survival Advantage in pre-BI Cells Down-modulation of CD 19 , Enhances Migration to CXCL 12 , PAX 5 / TEL Acts as a Transcriptional Repressor Causing (2007) (0)
miRNA-regulated gene expression differs in celiac disease patients according to the age of presentation (2015) (0)
Cytokine Induced Killer (CIK) Cells Transduced with an Anti-CD19 Chimeric Receptor Containing 4-1BB Acquire Powerful Anti-Leukemic Activity. (2006) (0)
Acute Lymphoblastic Leukemia Natural History in Neurofibromatosis Type 1 Monozygotic Twins (2011) (0)
Challenging Management of Severe Differentiation Syndrome in Pediatric Acute Promyelocytic Leukemia Treated with ATRA/ATO (2022) (0)
A multidisciplinary approach to screen the post-COVID-19 conditions (2023) (0)
Bone Marrow Mesenchymal Stromal Cells and Inflammation Contribute to ETV6-RUNX1+ Preleukemic Cells Persistence and DNA Damaging (2018) (0)
Early Response Does Not Impact on the Long-Term Outcome of Children and Adolescents with Chronic Myeloid Leukemia Treated with High-Dose Imatinib. the Italian Experience (2015) (0)
Minimal Residual Disease and Outcome Characteristics in Infant KMT2A-Germline Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol (2021) (0)
Loss of PTEN in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients: Proteomic and Molecular Characterization (2014) (0)
Early Response And Minimal Residual Disease Testing In Childhood ALL : Methodologies And Clinical Application (2005) (0)
Reciprocal Transcripts AML-M4Eo Patient With a t(1;12)(q25;p13): Molecular Cloning of Both The Tyrosine Kinase Abl-Related Gene ARG Is Fused toETV6 in an (2013) (0)
ImmunoTyper-SR: A computational approach for genotyping immunoglobulin heavy chain variable genes using short-read data. (2022) (0)
Clonal Changes Are Frequent in Relapsed TEL-AML1+ ALL and Predominate in Young Children. (2004) (0)
The EuroChimerism Concept for a Standardized Approach to Chimerism Analysis Following Allogeneic Stem Cell Transplantation. (2006) (0)
Short Time Latency in Infant Leukemia with ETV6/RUNX1 fusion Gene (2008) (0)
The chemerin/CMKLR1 axis regulates intestinal graft-versus-host disease (2023) (0)
Life-threatening cardiogenic shock in a pediatric patient with SARS-CoV-2-associated myocarditis treated with remdesivir: a case description and report of similar cases from the Literature (2020) (0)
The use of antibodies to CD20 for the treatment of graft versus host disease (2000) (0)
How I Treat How I treat infant leukemia (2018) (0)
Incidence and Therapeutic Implications of Germline TP53 Mutations in Hypodiploid Childhood Acute Lymphoblastic Leukemia: A Retrospective Analysis of the Italian Cohort (2020) (0)
Childhood Leukemias: Minimal residual disease (2006) (0)
Long Term Results of the AIEOP-All-95 Trial for Childhood Acute Lymphoblastic Leukemia. An Insight on the Prognostic Value of Dna Index in the Frame of BFM-Based Chemotherapy. (2007) (0)
A case of beta-thalassaemia major resistant to standard treatment (2010) (0)
Effects of hospital early childcare intervention in young children with cancer (2020) (0)
Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the Acute Myeloid Leukemia burden. (2023) (0)
Favorable Outcome of Children with Acute Megakaryoblastic Leukemia Treated with the AIEOP AML 2002/01 Protocol (2012) (0)
Pediatric immune myelofibrosis (PedIMF) as a novel and distinct clinical pathological entity (2022) (0)
With the Monoclonal Antibody PGM 3 ( Anti-PML ) Immunocytochemical Diagnosis of Acute Promyelocytic Leukemia ( M 3 ) (1997) (0)
286 Perspectives in cell and gene therapy of childhood leukaemia (2009) (0)
3081 – LCK DRUG TARGETING IN PAX5 REARRANGED CASES IN POOR RISK CHILDHOOD B-CELL PRECURSORS ACUTE LYMPHOBLASTIC LEUKAEMIA (2022) (0)
Impact of Additional Intensive L-Asparaginase Therapy during Consolidation Phase for High-Risk Acute Lymphoblastic Leukemia: Results of a Randomized Controlled Trial in the AIEOP-BFM ALL 2009 Protocol (2022) (0)
Chimeric Antigen Receptor for Specific Targeting of Acute Myeloid Leukemia (2012) (0)
Establishment and Characterization of a New Granulocyte-Macrophage Colony-Stimulating Factor-Dependent and Interleukin-3-Dependent Human Acute Myeloid Leukemia Cell Line ( GF-DS ) (2003) (0)
1407 The European Strategic Plan for children and adolescents with cancer (2015) (0)
Response to High Dose Imatinib and Long-Term Outcome in Children and Adolescents with Previously Untreated Chronic Myeloid Leukemia in Chronic Phase. the Italian Experience (2014) (0)
Prospective and Retrospective Observational Study in Adult and Pediatric Patients with GATA2 Variants (GATA2 Deficiency) (2022) (0)
Carcik-CD19 Cells Expand In Vivo Toward a CD8+ Memory Phenotype and Their Persistence Is Associated with a Longer Duration of Response (2022) (0)
Prognostic Value of Immunophenotype In Infant ALL – Results of the INTERFANT'99 Study (2010) (0)
A case of Philadelphia Positive Acute Lymphoblastic Leukaemia with three different phenotypic lineage, each one presenting the same BCR-ABL hybrid transcript. (2009) (0)
Role Of Long Pentraxin 3 (PTX3) In Wound Closure Induced By Bone Marrow-Derived Mesenchymal Stromal Cells (2013) (0)
TFPT (TCF3/E2A fusion partner) (2011) (0)
Chemerin Produced By Mesenchymal Stromal Cells (MSC) Is an Important Factor for In Vivo macrophage Migration (2015) (0)
New Isoforms of the ZFM1 Gene: a Growing Family of Signal Transduction and Activator of RNA (STAR) Proteins (1998) (0)
First clinical experiences with Gemtuzumab ozogamicin (GO, Mylotarg (c)) in CD33 positive relapsed/refractory leukemia in children (2003) (0)
Refinement of IKZF1 Genomic Status in Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia (2014) (0)
Preclinical evaluation of donor-derived sleeping beauty modified CD19CAR+ lymphocytes for the treatment of acute lymphoblastic leukemia (2017) (0)
Expression pattern of the RARcr-PML fusion gene in acute promyelocytic leukemia (0)
Role of MRD in Ph+ Pediatric Acute Lymphoblastic Leukemia Patients Treated with and without Tirosine Kinase Inhibitor in the Esphall Study (2012) (0)
Study )rearranged acute lymphoblastic leukemia: results from the Interfant-99 MLL ( mixed-lineage-leukemia poor prognostic subgroup of infants with Improved outcome with hematopoietic stem cell transplantation in a (2010) (0)
Methodology for the Start-up of a Pediatric Hematopoietic Stem Cell Transplant Unit (pHSCTU) in Middle-Income Countries (MICs): An Exportable Model? (2019) (0)
Genetics Directing Therapy in Acute Lymphocytic Leukemia: Identifying Risk, Defining Targets (2015) (0)
Use of antibodies against surface antigens for the treatment of graft versus host disease (1999) (0)
Fine Tuning of Surface CRLF2 Expression and Its Associated Signalling Profile in Childhood B Cell Precursor Acute Lymphoblastic Leukemia (2012) (0)

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