Andreas Trumpp
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(Suggest an Edit or Addition)Andreas Trumpp's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Bone-marrow haematopoietic-stem-cell niches (2006) (1387)
- IFNα activates dormant haematopoietic stem cells in vivo (2009) (1094)
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair (2009) (1065)
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair (2008) (996)
- Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay (2013) (926)
- c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. (2004) (805)
- Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the Pten Tumor Suppressor Gene in Vivo (2001) (802)
- Human haematopoietic stem cell lineage commitment is a continuous process (2017) (631)
- Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors (2015) (615)
- Senescence-associated reprogramming promotes cancer stemness (2017) (564)
- The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in (2011) (551)
- Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. (1999) (516)
- Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells (2015) (482)
- c-Myc regulates mammalian body size by controlling cell number but not cell size (2001) (460)
- Awakening dormant haematopoietic stem cells (2010) (399)
- The evolving concept of cancer and metastasis stem cells (2012) (398)
- DNA Hypomethylation Perturbs the Function and Survival of CNS Neurons in Postnatal Animals (2001) (364)
- Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells. (2005) (358)
- Combined single-cell and spatial transcriptomics reveals the molecular, cellular and spatial bone marrow niche organization (2019) (355)
- Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit. (2014) (347)
- Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors. (2015) (320)
- Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors (2016) (311)
- Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy (2017) (291)
- Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment (2007) (284)
- Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. (2008) (279)
- Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. (2014) (279)
- Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background. (2005) (275)
- Dormant and Self‐Renewing Hematopoietic Stem Cells and Their Niches (2007) (251)
- Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer (2012) (250)
- BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation (2017) (228)
- Endothelial Notch1 Activity Facilitates Metastasis. (2017) (208)
- Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis (2018) (208)
- Balancing dormant and self-renewing hematopoietic stem cells. (2009) (195)
- Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion (2019) (195)
- More than just proliferation: Myc function in stem cells. (2005) (194)
- Mechanisms of Disease: cancer stem cells—targeting the evil twin (2008) (190)
- Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause (2016) (188)
- A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies (2018) (185)
- What does the concept of the stem cell niche really mean today? (2012) (182)
- Targeting leukemic stem cells by breaking their dormancy (2010) (175)
- Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis (2015) (171)
- Causes and Consequences of Hematopoietic Stem Cell Heterogeneity. (2018) (169)
- CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma (2016) (168)
- Toward modeling the bone marrow niche using scaffold-based 3D culture systems. (2011) (165)
- Nestin‐Cre transgenic mouse line Nes‐Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite‐derived tissues (2006) (164)
- High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling (2011) (160)
- Conditional Mutation of Rb Causes Cell Cycle Defects without Apoptosis in the Central Nervous System (2003) (156)
- Nestin expression in pancreatic exocrine cell lineages (2004) (150)
- c-Myc Is Required for the Formation of Intestinal Crypts but Dispensable for Homeostasis of the Adult Intestinal Epithelium (2005) (149)
- Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis (2014) (141)
- The Myc trilogy: lord of RNA polymerases (2005) (138)
- Neurotrophin–3 is required for proper cerebellar development (1999) (136)
- Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations (2017) (135)
- Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling. (2011) (133)
- C‐Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia (2008) (129)
- Circulating miRNAs with prognostic value in metastatic breast cancer and for early detection of metastasis. (2016) (127)
- Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation (2008) (121)
- Survival of pancreatic cancer cells lacking KRAS function (2017) (119)
- The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer (2012) (114)
- Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP‐mediated recombination in the mouse (2000) (110)
- Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors (2018) (110)
- Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure. (2016) (103)
- Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice. (2009) (102)
- Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts (2011) (101)
- Myc's other life: stem cells and beyond. (2009) (95)
- Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene. (2006) (89)
- Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function (2008) (88)
- An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging (2015) (87)
- Estimating Dormant and Active Hematopoietic Stem Cell Kinetics through Extensive Modeling of Bromodeoxyuridine Label-Retaining Cell Dynamics (2009) (86)
- Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs (2020) (85)
- Selective Requirement for c-Myc at an Early Stage of Vα14i NKT Cell Development 1 (2009) (84)
- Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells. (2012) (79)
- A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer (2015) (78)
- The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patients (2015) (73)
- Co-expression of MET and CD47 is a novel prognosticator for survival of luminal-type breast cancer patients (2014) (71)
- c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo (2008) (70)
- Haematopoietic stem cells in perisinusoidal niches are protected from ageing (2019) (70)
- Serial enumeration of circulating tumor cells predicts treatment response and prognosis in metastatic breast cancer: a prospective study in 393 patients (2014) (68)
- Colonic Epithelial Expression of ErbB2 Is Required for Postnatal Maintenance of the Enteric Nervous System (2003) (68)
- Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF–p53 pathway (2008) (67)
- Chromosome Dynamics in the Yeast Interphase Nucleus (66)
- The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis. (1992) (65)
- Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response (2017) (64)
- Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer (2013) (64)
- Proteomic Cornerstones of Hematopoietic Stem Cell Differentiation: Distinct Signatures of Multipotent Progenitors and Myeloid Committed Cells* (2012) (63)
- Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer (2017) (61)
- Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma (2016) (60)
- Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand (2018) (59)
- Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal (2016) (58)
- Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas (2007) (58)
- c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. (2006) (57)
- Innovations, challenges, and minimal information for standardization of humanized mice (2020) (57)
- Breaking the cell cycle of HSCs by p57 and friends. (2011) (56)
- Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In Vivo. (2017) (52)
- Nestin‐Cre mediated deletion of Pitx2 in the mouse (2006) (49)
- Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics (2018) (48)
- Lineage- and stage-restricted lentiviral vectors for the gene therapy of chronic granulomatous disease (2011) (48)
- N-myc Controls Proliferation, Morphogenesis, and Patterning of the Inner Ear (2011) (48)
- The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features (2015) (47)
- Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations. (2020) (46)
- CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma (2015) (45)
- Circulating free DNA integrity and concentration as independent prognostic markers in metastatic breast cancer (2018) (45)
- Hematopoietic stem cell quiescence and function are controlled by the CYLD–TRAF2–p38MAPK pathway (2015) (45)
- MALDI versus ESI: The Impact of the Ion Source on Peptide Identification. (2017) (44)
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair (vol 135, pg 1118, 2008) (2009) (44)
- The rarity of ALDH + cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients (2015) (43)
- Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin. (2020) (42)
- Quantitative proteomics reveals specific metabolic features of Acute Myeloid Leukemia stem cells. (2020) (41)
- Expression and prognostic significance of cancer stem cell markers CD24 and CD44 in urothelial bladder cancer xenografts and patients undergoing radical cystectomy. (2014) (41)
- Activated Src abrogates the Myc requirement for the G0/G1 transition but not for the G1/S transition. (2006) (41)
- Identification of evolutionarily conserved regulatory elements in the mouse Fgf8 locus (2006) (40)
- Pten loss in the bone marrow leads to G-CSF–mediated HSC mobilization (2013) (38)
- Single cell polarity in liquid phase facilitates tumour metastasis (2018) (38)
- Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model (2013) (37)
- Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states (2021) (37)
- Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2. (2015) (36)
- Selection and dynamics of embryonic stem cell integration into early mouse embryos (2016) (34)
- Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization (2019) (34)
- Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia (2017) (33)
- Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response. (2014) (33)
- Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules. (2019) (33)
- c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland (2009) (33)
- Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing (2014) (32)
- Inducible Gene and shRNA Expression in Resident Hematopoietic Stem Cells In Vivo (2010) (30)
- Transcriptome-wide Profiling and Posttranscriptional Analysis of Hematopoietic Stem/Progenitor Cell Differentiation toward Myeloid Commitment (2014) (30)
- Histone Acetyltransferase Cofactor Trrap Is Essential for Maintaining the Hematopoietic Stem/Progenitor Cell Pool1 (2009) (30)
- A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer (2015) (30)
- AMPK promotes survival of c‐Myc‐positive melanoma cells by suppressing oxidative stress (2018) (29)
- The protooncogene MYC can break B cell tolerance. (2005) (29)
- Convergence of cMyc and β‐catenin on Tcf7l1 enables endoderm specification (2015) (28)
- Plasma hyaluronic acid level as a prognostic and monitoring marker of metastatic breast cancer (2016) (28)
- Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence. (2014) (28)
- Regulation of Episomal Gene Expression by KRAB/KAP1-Mediated Histone Modifications (2009) (28)
- Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells. (2019) (27)
- Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations (2012) (27)
- Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism. (2020) (27)
- Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1 (2021) (26)
- Leukemic spleen cells are more potent than bone marrow-derived cells in a transgenic mouse model of CML (2012) (26)
- Defined Conditions for the Isolation and Expansion of Basal Prostate Progenitor Cells of Mouse and Human Origin (2015) (25)
- MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis (2022) (24)
- Bridging the information gap (2011) (24)
- Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response (2021) (23)
- c-Myc controls the development of CD8alphaalpha TCRalphabeta intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival. (2010) (23)
- Developmental vascular regression is regulated by a Wnt/β-catenin, MYC and CDKN1A pathway that controls cell proliferation and cell death (2018) (23)
- miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells. (2016) (21)
- Impact of apoptotic circulating tumor cells (aCTC) in metastatic breast cancer (2016) (21)
- Label retaining cells in cancer--the dormant root of evil? (2013) (20)
- Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells. (2019) (20)
- Identification and Validation of Novel Subtype-Specific Protein Biomarkers in Pancreatic Ductal Adenocarcinoma (2017) (20)
- Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B (2014) (20)
- TNF-α-producing macrophages determine subtype identity and prognosis via AP1 enhancer reprogramming in pancreatic cancer (2021) (20)
- Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs (2020) (17)
- The proteogenomic subtypes of acute myeloid leukemia. (2022) (17)
- Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients (2020) (16)
- Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis (2021) (16)
- The impact of type 2 diabetes on the outcome of localized renal cell carcinoma (2013) (16)
- A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition (2015) (16)
- HER2-targeted therapy influences CTC status in metastatic breast cancer (2020) (15)
- Development and characteristics of preclinical experimental models for the research of rare neuroendocrine bladder cancer. (2013) (15)
- Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation. (2021) (15)
- Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells. (2021) (13)
- The molecular signature of AML with increased ALDH activity suggests a stem cell origin (2018) (12)
- Maintenance of epithelial traits and resistance to mesenchymal reprogramming promote proliferation in metastatic breast cancer (2020) (12)
- The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells (2019) (12)
- Plasma S100P level as a novel prognostic marker of metastatic breast cancer (2016) (12)
- Constitutive gray hair in mice induced by melanocyte‐specific deletion of c‐Myc (2012) (12)
- Hematopoietic Stem Cell Niches (2009) (11)
- An interplay of NOX1-derived ROS and oxygen determines the spermatogonial stem cell self-renewal efficiency under hypoxia (2021) (11)
- Vitamin A/ retinoic acid signaling regulates hematopoietic stem cell dormancy (2017) (10)
- High prevalence of incidental and symptomatic venous thromboembolic events in patients with advanced pancreatic cancer under palliative chemotherapy: A retrospective cohort study. (2017) (10)
- Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells (2022) (9)
- Human haematopoietic stem cell lineage commitment is a continuous process (2017) (9)
- on an INK 4 a-Deficient BackgroundQ 61 Kof Activated N-Ras Metastasizing Melanoma Formation Caused by Expression (2005) (9)
- Stem cells make leukemia grow again (2017) (9)
- Antigen presentation safeguards the integrity of the hematopoietic stem cell pool. (2022) (9)
- Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer (2018) (9)
- OMIP‐059: Identification of Mouse Hematopoietic Stem and Progenitor Cells with Simultaneous Detection of CD45.1/2 and Controllable Green Fluorescent Protein Expression by a Single Staining Panel (2019) (8)
- c-Myc and activated Ras during skin tumorigenesis: cooperation at the cancer stem cell level? (2006) (8)
- Venetoclax synergizes with Gilteritinib in FLT3 wildtype high-risk Acute Myeloid Leukemia by suppressing MCL-1. (2022) (8)
- Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs (2021) (8)
- Potency finds its niches (2016) (7)
- Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF–p53 pathway (2009) (7)
- Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies (2018) (7)
- Combined Single-Cell and Spatial Transcriptomics to Deconvolute the Hematopoietic Stem Cell Niche (2018) (7)
- Circulating microRNAs as Surrogate Markers for Circulating Tumour Cells and Prognostic Markers in Metastatic Breast Cancer (2012) (6)
- In vivo fate mapping with SCL regulatory elements identifies progenitors for primitive and definitive hematopoiesis in mice (2009) (6)
- mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease (2021) (6)
- Ion source-dependent performance of 4-vinylpyridine, iodoacetamide, and N-maleoyl derivatives for the detection of cysteine-containing peptides in complex proteomics (2016) (6)
- The pivotal role of reactivity in the design of novel biotinylation reagents for the chemical-proteomics-based identification of vascular accessible biomarkers. (2016) (5)
- An Intrinsic Interferon Program Protects Stem Cells from Viral Infection. (2018) (5)
- A Stem Cell-Based Epigenetic Memory Mediates Interferon Response-Heterogeneity within the Hematopoietic System (2017) (5)
- Tuning mTORC1 activity for balanced self-renewal and differentiation. (2010) (5)
- c-Myc controls the development of CD 8 TCR intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15 – dependent survival (2010) (5)
- Versatile workflow for cell type resolved transcriptional and epigenetic profiles from cryopreserved human lung (2020) (4)
- Leukemic stem cells and therapy resistance in acute myeloid leukemia (2023) (4)
- MutaSeq reveals the transcriptomic consequences of clonal evolution in acute myeloid leukemia (2018) (4)
- Kooperation unter asymmetrischer Information : eine Verbindung von Prinzipal-Agenten-Theorie und Transaktionskostenansatz (1995) (4)
- Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion (2019) (4)
- Analysis of nonleukemic cellular subcompartments reconstructs clonal evolution of acute myeloid leukemia and identifies therapy‐resistant preleukemic clones (2021) (4)
- Recent advances in “sickle and niche” research - Tribute to Dr. Paul S Frenette - (2022) (3)
- A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia (2022) (3)
- The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features (2015) (3)
- Versatile workflow for cell type–resolved transcriptional and epigenetic profiles from cryopreserved human lung (2021) (3)
- Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation (2018) (3)
- Hematopoietic Stem Cells in Perisinusoidal Niches are Protected From Aging (2018) (2)
- ALTERNATIVE POLYADENYLATION REGULATES HEMATOPOIETIC STEM CELL METABOLISM (2019) (2)
- Neogenin regulates hematopoietic stem cell quiescence and maintenance (2017) (2)
- Human haematopoietic stem cell differentiation follows a continuous waddington-like landscape (2016) (2)
- Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype (2022) (2)
- CXCR3-expressing metastasis-initiating cells induce and exploit a fibroblast niche in the lungs to fuel metastatic colonization (2019) (2)
- γδ T cells license immature B cells to produce a broad range of polyreactive antibodies. (2022) (2)
- Therapy resistance mechanisms in hematological malignancies (2022) (2)
- The Netrin-1 - Neogenin Axis Regulates Hematopoietic Stem Cell Dormancy and Function with Implications for Stem Cell Ageing (2018) (2)
- Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis (2018) (2)
- Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia (2022) (2)
- The influence of prostatic anatomy and neurotrophins on basal prostate epithelial progenitor cells (2018) (2)
- Selenocysteine metabolism is a targetable vulnerability in MYCN-amplified cancers (2022) (2)
- Stress-Induced Activation of Dormant Hematopoietic Stem Cells In Vivo, (2011) (2)
- Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion (2018) (2)
- Targeting VLA 4 integrin and CXCR 2 mobilizes serially repopulating hematopoietic stem cells (2019) (2)
- Stress-induced exit from dormancy alters redox signaling in HSCs, resulting in de novo DNA damage and bone marrow failure in the absence of a functional fanconi anemia signaling pathway (2014) (2)
- Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer (2022) (2)
- Comparison of extraction methods for intracellular metabolomics of human tissues (2022) (2)
- Role of myc in melanoma (2011) (1)
- A Novel Enhancer Region 1.7Mb Downstream of the C-Myc Gene Drives Its Expression in Hematopoietic Stem and Progenitor Cells (2014) (1)
- The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patients (2015) (1)
- IFN-alpha PROMOTES PROLIFERATION OF DORMANT HSCS IN VIVO, MAKING THEM SUSCEPTIBLE TO ELIMINATION BY CHEMOTHERAPY (2008) (1)
- Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics (2018) (1)
- HAPLN1 is a driver for peritoneal carcinomatosis in pancreatic cancer (2022) (1)
- Chemotherapy-Induced Senescence Reprograms Lymphoma and Leukemia Cells into Latent Cancer Stem Cells That Are Susceptible to Conceptually Novel Treatments (2014) (1)
- Myc controls IL-15-driven expansion and translational machinery of NK cells (2022) (1)
- Driving differentiation: targeting APA in AML. (2022) (1)
- Combinatorial BCL-2 family expression in Acute Myeloid Leukemia Stem Cells predicts clinical response to Azacitidine/Venetoclax. (2023) (1)
- Activation of Dormant Hematopoietic Stem Cells In Vivo by the Endotoxin LPS. (2010) (1)
- Supplemental material for Myc / Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal (2016) (1)
- Science, Society and the Nobel Prize (2004) (1)
- 306 Subtype-specific Models of Pancreatic Ductal Adenocarcinoma Reveal Signaling Pathways That Can Be Exploited Therapeutically (2012) (1)
- The limb deformity gene encodes evolutionarily highly conserved proteins (1991) (1)
- S120: ACUTE MYELOID LEUKEMIA REPRESENTS A FERROPTOSIS-SENSITIVE CANCER ENTITY RAISING THE POSSIBILITY FOR NOVEL TARGETING STRATEGIES (2022) (1)
- Protein tyrosine kinase 2b inhibition reverts niche-associated resistance to tyrosine kinase inhibitors in AML (2022) (1)
- Inherent engraftment differences between CD45.1 and CD45.2 HSCs are caused by differential expression of Cxcr4 (2017) (1)
- A cluster of enhancer modules directs differential MYC expression along the normal and leukemic haematopoietic stem cell hierarchies (2017) (1)
- Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis (2015) (1)
- 147 The C-Myc and TNFα/NF-kB pathways are critically involved in the regulatory network between the undifferentiated prostate basal stem cell state and the more differentiated luminal prostate epithelial cells (2016) (1)
- Comparison of extraction methods for intracellular metabolomics (2021) (1)
- Leukemic Stem Cells of Monocytic AMLs Are Not-Resistant to BCL-2 Inhibition (2021) (1)
- Dauerhaftes Ansprechen auf Olaparib und endokrine Therapie bei einer Patientin mit metastasiertem luminalem Mammakarzinom und gBRCA-Mutation (2020) (0)
- Challenges and opportunities of CYP3A5 as novel drug target in pancreatic cancer subtypes (2016) (0)
- Altered HSC Metabolism in Response to Stress Leads to De Novo dna Damage and Cellular Attrition (2014) (0)
- Today@Biozentrum/Pharmazentrum Seminarreihen (2015) (0)
- Whole-genome bisulfite sequencing of HSCs and their immediate progeny identifies novel regulatory elements involved in self-renewal and early hematopoietic commitment (2014) (0)
- Stem/Progenitor Cell Pool Essential for Maintaining the Hematopoietic Histone Acetyltransferase Cofactor Trrap Is (2009) (0)
- HAPLN1 potentiates peritoneal metastasis in pancreatic cancer (2023) (0)
- P454: VENETOCLAX AND GILTERITINIB SYNERGIZE IN FLT3 WILDTYPE ACUTE MYELOID LEUKEMIA BY SUPPRESSION OF MCL-1 VIA COMBINED AXL AND FLT3 TARGETING (2022) (0)
- Paul S. Frenette (1965-2021). (2021) (0)
- Circulating tumor cells in metastatic breast cancer: Are they a strong and independent predictor of poor progression-free and overall survival? (2012) (0)
- 1123 ESTABLISHMENT OF PRIMARY TUMOR XENOGRAFTS IN IMMUNODEFICIENT MICE - THE ROLE OF CHRONIC GRAFT VERSUS HOST REACTIONS - IDENTIFICATION AND AVOIDANCE OF INVALID SCIENTIFIC RESULTS (2013) (0)
- ROBO1 Regulates the Junctional Actin Cytoskeleton of Pancreatic Tumor Cells Through the RhoA/ABI/Diaph1/NMII Pathway and Promotes Vasculogenic Mimicry (2021) (0)
- CRISPR-Cas9 mediated generation of a conditional poly(A) binding protein nuclear 1 (Pabpn1) mouse model reveals an essential role for hematopoietic stem cells (2022) (0)
- Survival of pancreatic cancer cells lacking KRAS function (2017) (0)
- Exploring Genetic and Non-Genetic Changes Driving Tumor Evolution in CK-AML at Single-Cell Resolution (2022) (0)
- Abstract 3650: Trace'n'Seq: Assessing neuronal infiltration and its impact in pancreatic ductal carcinoma (2022) (0)
- Global regulatory networks and Myc regulation in HSCs and early progenitors (2015) (0)
- Abstract P3-06-45: Concordance/discordance rates of HER2, ER, PR, and Ki67 in matched pair samples of primary (PBC) and metastatic breast cancer (MBC) tissues when comparing IHC with MammaTyper® RT-PCR kit (2015) (0)
- Transition out of HSC Dormancy By a Continuous Upregulation of Metabolism Is Controlled Via Dietary Vitamin A/ Retinoic Acid Signaling (2016) (0)
- Today@Biozentrum/Pharmazentrum Seminar Series (2015) (0)
- 291 Comparison of Conventional Cell Lines and Improved Models for Ovarian Carcinoma – Drug Targets and Cancer-stem Cell Markers (2012) (0)
- Central Nervous System Cycle Defects without Apoptosis in the Causes Cell Rb Conditional Mutation of (2003) (0)
- Abstract 1063: A clear cell renal cancer metastasis model identifies novel mediators of tumor aggressiveness and predictors of patient survival (2018) (0)
- Abstract P2-08-18: Gene and protein expression profiles of HER2, ER, PR, and Ki67 in matched pair samples of primary (PBC) and metastatic breast cancer (MBC) tissues (2016) (0)
- Macs - a Leukemic Stem Cell- Based Predictor of Clinical Response to Venetoclax and Other BH3 Mimetics for Acute Myeloid Leukemia (2022) (0)
- OBC: Contents (2004) (0)
- PO-302 Deconvolution of the tumour microenvironment of primary human pancreatic ductal adenocarcinoma and normal pancreas reveals specific deregulated signalling nodes (2018) (0)
- 407 Development of preclinical experimental models for the research of neuroendocrine bladder cancer (2014) (0)
- Virus infections differentially modulate the cell cycle state and functionality of dormant long-term hematopoietic stem cells in vivo (2015) (0)
- 63 Circulating Metastasis-initiating Cells in Breast Cancer (2012) (0)
- Targeting the Leukemic stem cell protein machinery by inhibition of mitochondrial pyrimidine synthesis (2022) (0)
- Serial enumeration of circulating tumor cells predicts treatment response and prognosis in metastatic breast cancer: a prospective study in 393 patients (2014) (0)
- Corrigendum: Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer (2017) (0)
- 3071 – HEALTHY AND MALIGNANT HEMATOPOIETIC STEM CELLS ACT AS IMMUNOREGULATORY ANTIGEN PRESENTING CELLS (2021) (0)
- 3032 – MOUSE MULTIPOTENT PROGENITOR 5 CELLS ARE LOCATED AT THE INTERPHASE BETWEEN HEMATOPOIETIC STEM AND PROGENITOR CELLS (2021) (0)
- biomedical research Of mice and models: improved animal models for (2015) (0)
- Abstract B77: CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma (2016) (0)
- S123: DECODING TRANSCRIPTOMIC AND EPIGENETIC CONSEQUENCES OF STRUCTURAL VARIANTS IN CK-AML AT SINGLE-CELL RESOLUTION (2022) (0)
- The global RNA and protein landscape of hematopoietic stem cells and their immediate progeny (2014) (0)
- Abstract 3714: Efficient derivation and expansion of tumor cell lines from primary and xenotransplanted pancreatic, ovarian and renal tumors (2019) (0)
- Abstract P2-02-06: Impact of apoptotic circulating tumor cells in metastatic breast cancer (2016) (0)
- Single cell polarity in liquid phase facilitates tumour metastasis (2018) (0)
- Abstract PD2-01: Exploring CDK4/6 inhibitor therapy response and drug resistance development at the single cell level in metastatic breast cancer CTCs (2020) (0)
- Metabolic cues for hematopoietic stem cells (2016) (0)
- 227 Identification of Novel Therapeutic Targets in Advanced Patient-matched Renal Cell Carcinoma Models (2012) (0)
- Mesenchymal and MDS stem cells shape an interactive disease unit in the bone marrow (2014) (0)
- Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietin. (2022) (0)
- Abstract A69: A novel mechanism mediates drug resistance in the exocrine-like pancreatic ductal adenocarcinoma (PDAC) subtype (2015) (0)
- Faculty Opinions recommendation of Myc influences global chromatin structure. (2006) (0)
- 1030 - REGULATION OF HEMATOPOIETIC AND IMMUNE ESCAPE OF AML STEM CELLS (2019) (0)
- Bioluminescence in Vivo Imaging Improves the Model of Individual Patients' AML Cells Growing in Mice for Sensitive and Reliable Preclinical Treatment Trials on Various Genetic Subgroups (2014) (0)
- Hematopoietic Stem Cells are Regulated by Alternative Polyadenylation (2018) (0)
- Prognostic impact of changes in circulating tumor cells (CTC) in metastatic breast cancer (MBC). (2013) (0)
- Regulatory elements of maize storage protein genes (1990) (0)
- Abstract 652: An androgen receptor-associated transcription factor regulates fatty acid metabolism driving tumor growth in androgen receptor-positive breast cancer (2022) (0)
- Paul S. Frenette (1965–2021) (2021) (0)
- Versatile workflow for storage, characterization and cell-type resolved transcriptional and epigenetic profiles of human lung samples (LSC-2020) (2020) (0)
- What does the concept of the stem cell niche really mean today? (2012) (0)
- O-013 Mesenchymal stromal cells support significant engraftment of low-risk myelodysplastic syndromes (MDS) in a murine xenograft model (2013) (0)
- Faculty Opinions recommendation of Prospective identification of tumorigenic breast cancer cells. (2003) (0)
- Paul S. Frenette (1965-2021). (2021) (0)
- Quantitative Bone-Marrow Imaging Reveals Niche Signatures of Distinct Types of Adult and Juvenile Hematopoietic Stem Cells (2018) (0)
- Brief Report Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells (2021) (0)
- Given the heterogeneity of putative leukemia stem cells, is this concept still clinically relevant? (2016) (0)
- Myc controls NK cell development, IL-15-driven expansion, and translational machinery (2023) (0)
- The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells (2019) (0)
- Clonal hierarchies and dynamic evolution in Myelodysplastic Syndromes (MDS) upon therapy (2016) (0)
- Multi-Layered Single-Cell Transcriptional Profiling of All Bone and Bone Marrow Populations Provides a Systems View of the Mesenchymal and Hematopoietic Stem Cell Niche (2018) (0)
- 3171 – MOUSE MULTIPOTENT PROGENITOR 5 CELLS ARE LOCATED AT THE INTERPHASE BETWEEN HEMATOPOIETIC STEM AND PROGENITOR CELLS (2022) (0)
- homeostasis c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell (2011) (0)
- 2007 – DIFFERENTIAL ALTERNATIVE POLYADENYLATION LANDSCAPES MEDIATE HEMATOPOIETIC STEM CELL ACTIVATION AND REGULATE GLUTAMINE METABOLISM (2020) (0)
- P447: BCL2-INHIBITION TARGETS LEUKEMIC STEM CELLS IN ACUTE MYELOID LEUKEMIA INDEPENDENT OF MONOCYTIC BLAST POPULATIONS (2022) (0)
- Inhibitors in control (1999) (0)
- A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies (2018) (0)
- hematopoietic progenitor cells via ROS signaling induced mobilization of - Enhanced c-Met activity promotes G-CSF (2011) (0)
- HSC Exit From Dormancy Provokes De Novo DNA Damage, Leading To Bone Marrow Failure If Unresolved By The Fanconi Anemia Pathway (2013) (0)
- Significant Engraftment of Immature Hematopoietic Cells From Patients with Low Risk Myelodysplastic Syndromes (MDS) in Immunodeficient Mice (2012) (0)
- Abstract 960: HAPLN1 increases peritoneal carcinomatosis by inducing tumor cell hyperplasticity (2022) (0)
- Functional and molecular segregation of in vitro specified hematopoietic stem and progenitor cells using a HOXB4 knock-in reporter (2016) (0)
- Abstract B50: A patient-derived renal cell carcinoma model as a platform for the identification of novel diagnostic markers and therapeutic targets (2013) (0)
- Resolving drug effects in patient-derived cancer cells links organoid responses to genome alterations (2017) (0)
- Glutamine protects mouse spermatogonial stem cells against NOX1-derived ROS for sustaining self-renewal division in vitro. (2023) (0)
- 43PEFFECTS OF MTOR INHIBITION ON IR/IGF-1R SIGNALLING IN PIK3CA-MUTATED, TAMOXIFEN RESISTANT BREAST CANCER (2013) (0)
- Abstract PD9-07: Mdm2 gene amplification in estrogen receptor-positive breast cancer cells is associated with enhanced solid tumor growth and pronounced metastatic potential in humanized tumor mice (HTM) and a poor outcome of patients with luminal breast cancer (2022) (0)
- Abstract IA05: Viral Mimicry in Pancreatic Cancer (2020) (0)
- The Molecular and Functional Foundations of Conducive Somatic Cell Reprogramming to Ground State Pluripotency (2018) (0)
- Inflammation-driven fast-track differentiation of HSCs into the megakaryocytic lineage (2014) (0)
- Versatile workflow for storage, characterization and cell-type resolved transcriptional and epigenetic profiling of human lung samples. (2020) (0)
- The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a study in 107 patients (2014) (0)
- The role of the lncRNA Meg3 in the adult hematopoietic compartment (2017) (0)
- 84: Mesenchymal and MDS stem cells shape an interactive disease unit in the bone marrow (2014) (0)
- 65 MYELODYSPLASTIC SYNDROMES ARE CHARACTERIZED BY RECURRENT PATTERNS IN PATIENT-INDIVIDUAL MUTATIONAL HIERARCHIES THAT ARE SUBJECT TO HIGHLY DYNAMIC SUBCLONAL EVOLUTION DURING THERAPY AND DISEASE PROGRESSION (2015) (0)
- Differential expression of endothelial protein C receptor (EPCR) in hematopoietic stem and multipotent progenitor cells in young and old mice. (2023) (0)
- In-Depth Quantitative Multiplex Proteomics Reveal Subtype-Specific Differences Among Functionally Validated AML Stem Cell Populations (2014) (0)
- Identification Of Novel Markers Of Human AML Stem Cells Using High Resolution Proteomics and Transcriptomics (2013) (0)
- Abstract 3374: Large-scale single-cell whole transcriptomic analyses reveal distinct malignant phenotypes of CTCs from NSCLC patients (2022) (0)
- Quantitative Analysis of Patient-Specific Lesions in Primary and Xenografted Myelodysplastic Syndromes Reveals Complex Hierarchies and Subclonal Diversity That Evolve during Disease Progression (2014) (0)
- 281PCell-free circulating DNA as independent prognostic markers in metastatic breast cancer (2017) (0)
- Haematopoietic stem cells in perisinusoidal niches are protected from ageing (2019) (0)
- ACUTE LEUKEMIAS XV (2015) (0)
- Dormant and Activated Stem Cells during Homeostasis Injury and Cancer (2009) (0)
- Identification and characterization of novel functional markers of EHT (2017) (0)
- Loss of sparc protects hematopoietic stem cells from the toxic effects of repeated cycles of chemotherapy by accelerating their return to quiescence (2013) (0)
- Malignant Myeloma Cells Impair Phenotype and Function of stem and Progenitor Cells. (2009) (0)
- A non-canonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML. (2023) (0)
- The Disease-Related Bone Marrow Microenvironment Alters Hematopoietic Stem and Progenitor Function in Multiple Myeloma Patients (2011) (0)
- Exit from HSC dormancy by a continuous upregulation of metabolism is controlled via vitamin A/ retinoic acid (2016) (0)
- MDS-Derived Stromal Cells Exhibit Altered Gene Expression and Support The Engraftment Of lin-CD34+CD38- Disease-Initiating Stem Cells In a Xenograft Model Of Lower Risk MDS (2013) (0)
- Abstract IA22: CYP3A5 mediates resistance to small molecule inhibitors in a subtype of pancreatic ductal adenocarcinoma (2016) (0)
- Retained functional normal and preleukemic HSCs at diagnosis are associated with good prognosis in DNMT3AmutNPM1mut AMLs (2022) (0)
- PO-187 Liquid-phase polarity facilitates attachment, adhesion and metastasis of tumour cells (2018) (0)
- PO-395 Mechanistic investigation of epigenetic modifications induced by metabolic changes in AML (2018) (0)
- Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs (2020) (0)
- CYTIDINE DEAMINASES SHAPE THE GENOME OF GERMINAL CENTER B CELL DERIVED LYMPHOMA (2021) (0)
- BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation (2017) (0)
- Cellular deconvolution and expression analysis of Stromal and Epithelial cells directly isolated from human Pancreatic Ductal Adenocarcinoma (PDAC) (2017) (0)
- Abstract 1050: Efficient derivation and expansion of tumor cell lines from primary and xenotransplanted pancreatic tumors (2018) (0)
- Next Generation Sequencing-Based Molecular Dissection Of Lineage-Specific Mutational Hierarchies In Oligoclonal Primary and Xenografted Myelodysplasia (2013) (0)
- Regulation of Episomal Gene Expression by KRAB/KAP1-Mediated Histone Modifications (cid:1) (2009) (0)
- hematopoietic stem and progenitor cells + derived CD34 - related deregulation of bone marrow - Multiple myeloma (2013) (0)
- Complex genotype-phenotype relationships shape the response to treatment of Down Syndrome Childhood Acute Lymphoblastic Leukaemia (2022) (0)
- Abstract A61: Exploring the PDAC-subtype-associated microenvironment in PDX models and patients (2015) (0)
- Functional Analysis of Different Haematopoietic Stem Cell Subsets (2014) (0)
- Global landscape of hematopoietic stem cells and multipotent progenitors (2013) (0)
- After 25 years of research into the proto-oncogene c-myc, there is a light at the end of the tunnel (2002) (0)
- Detection and Isolation of Circulating Tumor Cells from Breast Cancer Patients Using CUB Domain-Containing Protein 1. (2023) (0)
- Endothelial Notch 1 Activit y Facilitates Metastasis Graphical Abstract Highlights (0)
- 3123 – DELINEATING THE HIERARCHICAL ORGANIZATION AND LINEAGE HETEROGENEITY OF THE MOUSE HSC AND MPP NETWORK (2022) (0)
- COGNITION – Präzisionsmedizin bei Brustkrebs im Frühstadium (2020) (0)
- Zur prognostischen Relevanz des CTC-Status bei Progress des metastasierten Mammakarzinoms (2018) (0)
- Eine mdm2 Genamplifikation ist mit Progression und Metastasierung des luminalen Mammakarzinoms im humanisierten Tumormausmodell (hPDX) assoziiert, sowie mit einem ungünstigen klinischen Verlauf der Erkrankung (2022) (0)
- Konkordanz-Analyse von Primärtumor, Metastase und CTC mithilfe von IHC, RT-PCR und CellSearch bei metastasiertem Mammakarzinom (2015) (0)
- Vergleich der Anzahl zirkulierender Tumorzellen mit dem Proliferationsmarker Ki-67 beim metastasierten Mammakarzinom (2018) (0)
- Büroflächenleerstand in Berlin (2005) (0)
- Zur prognostischen Relevanz des CTC-Status bei Progress des metastasierten Mammakarzinoms (2017) (0)
- Identifikation stammzellspezifischer Markerproteine beim Ovarialkarzinom (2014) (0)
- Zirkulierende Tumorzellen zur individuellen Therapiekontrolle beim metastasierten Mammakarzinom (2017) (0)
- Serielle Bestimmung von zirkulierenden Tumorzellen (CTC) zur Prädiktion von Therapieansprechen und Prognose beim metastasierten Mammakarzinom (MBC) – eine prospektive Studie an 393 Patientinnen (2014) (0)
- Prognostische Relevanz von CTC-Status und Kinetik bei erneutem Progress des metastasierten Mammakarzinoms (2017) (0)
- Prognostische Bedeutung apoptotischer zirkulierender Tumorzellen (aCTCs) bei metastasiertem Mammakarzinom (MBC) (2015) (0)
- Dauerhaftes Ansprechen auf Olaparib und endokrine Therapie bei einer Patientin mit metastasiertem luminalem Mammakarzinom und gBRCA-Mutation (2020) (0)
- COGNITION - Präzisionsmedizin bei Brustkrebs im Frühstadium (2020) (0)
- Zirkulierende miRNAs als prognostische und prädiktive Marker beim metastasierenden Mammakarzinom (2011) (0)
- Serielle Enumeration von CTC zur Prädiktion von Therapieansprechen und Prognose beim metastasierten Mammakarzinom – Analyse der Kinetik intakter und apoptotischer CTC (2014) (0)
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What Schools Are Affiliated With Andreas Trumpp?
Andreas Trumpp is affiliated with the following schools:
