Andrew Ewald
#93,177
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American cell biologist
Andrew Ewald's AcademicInfluence.com Rankings
Andrew Ewaldbiology Degrees
Biology
#8481
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#11566
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Cell Biology
#765
World Rank
#781
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Biology
Andrew Ewald's Degrees
- PhD Cell Biology University of California, San Francisco
- Bachelors Biology Stanford University
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Why Is Andrew Ewald Influential?
(Suggest an Edit or Addition)According to Wikipedia, Andrew Ewald is a professor of cell biology at Johns Hopkins University School of Medicine. He is known for his contributions in the field of metastatic breast cancer research. Education Ewald earned a BS in physics from Haverford College in 1997. He then went on to complete a PhD in 2003 from the California Institute of Technology in biochemistry and molecular biophysics. He researched in Scott Fraser's Lab where he studied light microscopy which would later influence his research.
Andrew Ewald's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Matrix metalloproteinases and the regulation of tissue remodelling (2007) (2578)
- Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development (2003) (2212)
- Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program (2013) (615)
- Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. (2008) (586)
- Three-dimensional organotypic culture: experimental models of mammalian biology and disease (2014) (578)
- PDGFRβ+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival (2005) (558)
- Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters (2016) (519)
- Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. (2012) (416)
- E-cadherin is required for metastasis in multiple models of breast cancer (2019) (413)
- A collective route to metastasis: Seeding by tumor cell clusters (2016) (391)
- ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium (2012) (370)
- GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. (2008) (341)
- Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration. (2010) (315)
- Twist1-induced dissemination preserves epithelial identity and requires E-cadherin (2014) (195)
- Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy (2008) (188)
- A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis (2014) (188)
- The MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium. (2007) (182)
- Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis. (2008) (175)
- Calcium signaling during convergent extension in Xenopus (2001) (162)
- Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis (2008) (153)
- A molecular switch for the orientation of epithelial cell polarization. (2014) (153)
- Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium (2012) (134)
- Cell–cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis (2015) (114)
- Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity. (2019) (113)
- 3D culture assays of murine mammary branching morphogenesis and epithelial invasion. (2015) (107)
- Surface imaging microscopy, an automated method for visualizing whole embryo samples in three dimensions at high resolution (2002) (96)
- Illuminating breast cancer invasion: diverse roles for cell-cell interactions. (2014) (96)
- The independent roles of mechanical, structural and adhesion characteristics of 3D hydrogels on the regulation of cancer invasion and dissemination. (2013) (95)
- Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. (2007) (94)
- An expanded universe of cancer targets (2021) (86)
- Adhesion in mammary development: novel roles for E-cadherin in individual and collective cell migration. (2015) (86)
- The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures. (2010) (81)
- Monitoring of vital signs for long-term survival of mice under anesthesia. (2011) (76)
- Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation (2004) (76)
- Cellular mechanisms regulating epithelial morphogenesis and cancer invasion. (2010) (75)
- Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy (2019) (64)
- Mammary epithelial tubes elongate through MAPK-dependent coordination of cell migration (2016) (64)
- Myoepithelial cells are a dynamic barrier to epithelial dissemination (2018) (60)
- Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis (2008) (59)
- HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24 (2016) (55)
- HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche (2017) (53)
- Mammary ductal elongation and myoepithelial migration are regulated by the composition of the extracellular matrix (2013) (52)
- Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy. (2011) (51)
- Cancer cells educate natural killer cells to a metastasis-promoting cell state (2020) (50)
- Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells (2014) (48)
- Cellular foundations of mammary tubulogenesis. (2014) (48)
- A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer (2017) (46)
- Coordination of Receptor Tyrosine Kinase Signaling and Interfacial Tension Dynamics Drives Radial Intercalation and Tube Elongation. (2018) (44)
- Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer (2014) (43)
- Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome (2020) (32)
- Practical considerations for long-term time-lapse imaging of epithelial morphogenesis in three-dimensional organotypic cultures. (2013) (32)
- GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity (2016) (31)
- Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects (2020) (31)
- A Tissue-Engineered 3D Microvessel Model Reveals the Dynamics of Mosaic Vessel Formation in Breast Cancer (2020) (31)
- Mechano-induced cell metabolism promotes microtubule glutamylation to force metastasis. (2021) (30)
- Preparation of mice for long-term intravital imaging of the mammary gland. (2011) (30)
- TRPV1 is a physiological regulator of μ-opioid receptors (2017) (29)
- Isolation of mouse mammary organoids for long-term time-lapse imaging. (2013) (29)
- Organotypic culture assays for murine and human primary and metastatic-site tumors (2020) (27)
- Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids. (2018) (27)
- p114RhoGEF governs cell motility and lumen formation during tubulogenesis through a ROCK–myosin-II pathway (2015) (25)
- mTORC1 loss impairs epidermal adhesion via TGF-&bgr;/Rho kinase activation (2017) (24)
- Tumor-Resident Stromal Cells Promote Breast Cancer Invasion through Regulation of the Basal Phenotype (2020) (20)
- Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium (2012) (18)
- Genetic Engineering of Primary Mouse Intestinal Organoids Using Magnetic Nanoparticle Transduction Viral Vectors for Frozen Sectioning. (2019) (14)
- Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread (2018) (14)
- New tools for visualization and analysis of morphogenesis in spherical embryos (2005) (14)
- Twist1-positive epithelial cells retain adhesive and proliferative capacity throughout dissemination (2016) (13)
- On the role of p53 in the cellular response to aneuploidy (2021) (13)
- Twist1-induced epithelial dissemination requires Prkd1 signaling. (2019) (13)
- Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level (2021) (12)
- Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin (2022) (11)
- A model of intussusceptive angiogenesis. (2007) (11)
- Invasive leader cells: metastatic oncotarget (2014) (11)
- Neuroblastoma Invasion Strategies Are Regulated by the Extracellular Matrix (2021) (9)
- The changing role of natural killer cells in cancer metastasis (2022) (9)
- Engineering a 3D collective cancer invasion model with control over collagen fiber alignment. (2021) (9)
- Cancer: Sugar-coated cell signalling (2014) (9)
- Mosaic loss of non-muscle myosin IIA and IIB is sufficient to induce mammary epithelial proliferation (2017) (9)
- Intussusceptive angiogenesis in human metastatic malignant melanoma. (2021) (9)
- Between-tumor and within-tumor heterogeneity in invasive potential (2020) (7)
- Organoids in cancer research: a review for pathologist‐scientists (2021) (7)
- Pulling cells out of tumours (2017) (7)
- DOT1L Is a Novel Cancer Stem Cell Target for Triple-Negative Breast Cancer (2022) (6)
- Microscale pressure measurements based on an immiscible fluid/fluid interface (2019) (6)
- GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD (2020) (6)
- OrgDyn: feature- and model-based characterization of spatial and temporal organoid dynamics (2020) (5)
- Vertebrate Gastrulation: Separation Is Sticky and Tense (2008) (5)
- 3D cell biology – the expanding frontier (2017) (5)
- Journal of Cell Science: 130 (1) (2017) (4)
- Immunotherapy: Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy (Adv. Mater. 23/2019) (2019) (4)
- Metastasis inside‐out: dissemination of cancer cell clusters with inverted polarity (2018) (4)
- Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis (2008) (3)
- 3D Analysis of Multi-cellular Responses to Chemoattractant Gradients. (2019) (3)
- GDNF drives rapid tubule morphogenesis in novel 3D in vitro model for ADPKD. (2020) (2)
- Organoid Co-culture Methods to Capture Cancer Cell-Natural Killer Cell Interactions. (2022) (2)
- An Arresting Story about Basement Membrane Invasion. (2015) (2)
- Mosaic analysis reveals essential function of FGF receptor 2 in mammary gland branching morphogenesis (2006) (2)
- Abstract 1526: HOXA5 inhibits cell plasticity and stemness in breast cancer cells by reinforcing epithelial traits (2015) (1)
- Mammary epithelial tubes elongate through MAPK-dependent coordination of cell migration (2016) (1)
- Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer (2022) (1)
- Abstract A12: Screening for TWIST1 inhibitors as a novel therapy for oncogene-driven lung cancer. (2014) (1)
- Little is known about the dynamics of cancer cell death in response to therapy in the tumor microenvironment (2012) (0)
- Abstract NG06: The Trojan Horse Strategy: Packaging chemotherapeutics can help alleviate toxicity (2015) (0)
- Foxp3+ regulatory T cells migrate along blood vessels and at the tumor-stroma border. (2008) (0)
- Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion. (2023) (0)
- Cancer Therapy : Preclinical Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer (2014) (0)
- Abstract 1014: A framework for research scientists to include patient advocates in cancer research (2022) (0)
- Title: Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer (2014) (0)
- A Three Dimensional Analysis of Frog Gastrulation (2003) (0)
- Infiltration and migration of c-fms+ myeloid cells in the tumor microenvironment. (2008) (0)
- Gr1+ myeloid cells are a patrolling subpopulation of the tumor-infiltrating myeloid cells. (2008) (0)
- Twist1 triggers PKD1 expression to promote metastatic dissemination in breast cancer (2016) (0)
- c-fms+ myeloid cells migrate in the normal mammary gland. (2008) (0)
- Abstract 4771: Identification of inhibitors of TWIST1 as a treatment for lung cancer (2014) (0)
- Abstract 5019: HMGA1 amplifies Wnt signaling and expands the intestinal stem cell compartment to drive premalignant polyposis in transgenic mice (2017) (0)
- Triple negative breast tumors contain heterogeneous cancer cells expressing distinct KRAS-dependent collective and disseminative invasion programs (2023) (0)
- Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread (2018) (0)
- Interview with the Guest Editor – Andrew Ewald (2017) (0)
- Integrated Transcriptomic and Proteomic Analyses Reveal Role of the Hexosamine Biosynthetic Pathway in Invasion and Metastasis of Hepatocellular Carcinoma (2020) (0)
- 3D cell biology – the expanding frontier (2017) (0)
- Correction for Jiao et al., Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects (2020) (0)
- Abstract 368: Defining the invasive gene signature using patient derived pancreatic cancer organoids (2020) (0)
- Abstract PR-008: Identification and characterization of the molecular mechanisms of SCLC chemo-radiation resistance (2021) (0)
- Abstract BS2-1: Collective invasion in breast cancer is led by specialized cancer cells with basal gene expression (2015) (0)
- Abstract P3-01-01: A dual role of natural killer cells in breast cancer metastasis (2020) (0)
- Carcinoma-associated fibroblasts in different tumor microenvironments. (2008) (0)
- INVOLVEMENT OF LUNG DENDRITIC CELLS DURING EARLY STAGES OF BREAST CANCER LUNG METASTASIS by (2020) (0)
- Abstract 3926: Establishment of patient-derived organoids asex vivotool to characterize the molecular mechanisms of SCLC chemo-radiation resistance (2020) (0)
- 490f – Liver Cancer Organoids Model Drug Response Heterogeneity (2019) (0)
- Pitavastatin Selectively Kills PTEN Knock Out Cells and Cancer Organoids in Mouse Model via the Mevalonate Pathway (2019) (0)
- 490e – Complext Patient Derived Organoids(CPDOS) Modeling for Anti-Cancer Drug Screening (2019) (0)
- Abstract C39: Building a novel molecular model for Twist1-induced epithelial dissemination (2013) (0)
- Quantitative real-time analysis of collective cancer invasion and dissemination (2015) (0)
- Twist1 induces dissemination by activating an epithelial motility program that requires E‐cadherin (LB230) (2014) (0)
- Abstract IA19: Microenvironmental regulation of breast cancer invasion, dissemination, and lung colonization (2016) (0)
- Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia. (2008) (0)
- Coordinate regulation of cell motility and intercellular adhesion during mammary branching morphogenesis (2010) (0)
- c-fms+ myeloid cells migrate in response to wounding on the surface of a normal mammary gland (2009) (0)
- Molecular regulation of collective epithelial migration during mammary branching morphogenesis (2008) (0)
- Collective cell migration is spatiotemporally regulated during mammary epithelial bifurcation. (2023) (0)
- Myeloid cells extravasate and infiltrate late carcinoma lesions. (2009) (0)
- Abstract P1-05-02: Epithelial-to-epithelial transition precedes collective breast cancer invasion (2012) (0)
- CD11c+ dendritic-like cells migrate at the tumor-stroma border. (2008) (0)
- Identification and Characterization of the Molecular Mechanisms of SCLC Chemo-Radiation Resistance. (2021) (0)
- Twist1 induces dissemination by activating an epithelial motility program that requires E‐cadherin (479.2) (2014) (0)
- Editorial Overview: Integration of dynamic processes in cell behaviour and tissue architecture. (2018) (0)
- Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis (2015) (0)
- Abstract IA17: Collective epithelial routes to metastatic spread (2016) (0)
- E-cadherin is required for metastasis in multiple models of breast cancer (2019) (0)
- Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters. (2023) (0)
- Improving the odds together: a framework for breast cancer research scientists to include patient advocates in their research (2022) (0)
- The molecular control of cell movements during early vertebrate development (2003) (0)
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