Andrey Korshunov
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Computer Science
Andrey Korshunov's Degrees
- Masters Computer Science Stanford University
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Andrey Korshunov's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma (2012) (2074)
- International network of cancer genome projects (2010) (1839)
- Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. (2012) (1532)
- Molecular subgroups of medulloblastoma: the current consensus (2011) (1507)
- DNA methylation-based classification of central nervous system tumours (2018) (1461)
- Analysis of the IDH1 codon 132 mutation in brain tumors (2008) (971)
- Medulloblastoma comprises four distinct molecular variants. (2011) (895)
- Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma (2011) (871)
- Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas (2012) (855)
- Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. (2015) (782)
- Dissecting the genomic complexity underlying medulloblastoma (2012) (777)
- K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas (2012) (766)
- Subgroup-specific structural variation across 1,000 medulloblastoma genomes (2012) (760)
- Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations (2012) (755)
- The whole-genome landscape of medulloblastoma subtypes (2017) (658)
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma (2013) (637)
- New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs (2016) (608)
- Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. (2014) (601)
- Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas. (2013) (575)
- Medulloblastomics: the end of the beginning (2012) (559)
- International Society of Neuropathology‐Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading (2014) (514)
- Epigenomic alterations define lethal CIMP-positive ependymomas of infancy (2014) (507)
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma (2014) (496)
- Characterization of R132H Mutation‐specific IDH1 Antibody Binding in Brain Tumors (2010) (478)
- BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. (2008) (456)
- Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. (2011) (437)
- Patterns of somatic structural variation in human cancer genomes (2020) (377)
- Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. (2016) (374)
- ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma (2014) (367)
- Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations (2012) (366)
- Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing (2014) (362)
- Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. (2013) (362)
- The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation (2013) (338)
- Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples (2011) (318)
- Clonal Selection Drives Genetic Divergence of Metastatic Medulloblastoma (2012) (317)
- Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. (2009) (303)
- ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis (2013) (298)
- Active medulloblastoma enhancers reveal subgroup-specific cellular origins (2016) (296)
- Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. (2013) (295)
- The clinical implications of medulloblastoma subgroups (2012) (280)
- An animal model of MYC-driven medulloblastoma. (2012) (279)
- Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers (2015) (269)
- Divergent clonal selection dominates medulloblastoma at recurrence (2016) (266)
- Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma (2009) (261)
- Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system (2013) (254)
- Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas (2013) (250)
- A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing (2015) (250)
- Cytogenetic prognostication within medulloblastoma subgroups. (2014) (242)
- IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO (2015) (241)
- Novel, improved grading system(s) for IDH-mutant astrocytic gliomas (2018) (236)
- Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma. (2014) (235)
- Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience (2018) (232)
- Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities (2015) (230)
- Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays (2013) (230)
- Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma. (2005) (229)
- Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling (2015) (225)
- The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants (2016) (220)
- Adult medulloblastoma comprises three major molecular variants. (2011) (215)
- Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort (2018) (212)
- Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma (2011) (211)
- Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct (2011) (204)
- Identification of Gains on 1q and Epidermal Growth Factor Receptor Overexpression as Independent Prognostic Markers in Intracranial Ependymoma (2006) (199)
- Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
- Molecular staging of intracranial ependymoma in children and adults. (2010) (192)
- Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets (2016) (188)
- mSWI/SNF (BAF) Complexes Facilitate Decatentation of DNA by Topoisomerase IIα (2013) (184)
- Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma (2014) (180)
- The Next Generation of Glioma Biomarkers: MGMT Methylation, BRAF Fusions and IDH1 Mutations (2011) (180)
- Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas. (2014) (168)
- HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth (2010) (167)
- Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival. (2004) (165)
- Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity (2013) (165)
- Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma (2013) (164)
- Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas (2018) (162)
- Recurrent MET fusion genes represent a drug target in pediatric glioblastoma (2016) (160)
- Genomic and Expression Profiling of Glioblastoma Stem Cell–Like Spheroid Cultures Identifies Novel Tumor-Relevant Genes Associated with Survival (2009) (160)
- Therapeutic Targeting of Ependymoma as Informed by Oncogenic Enhancer Profiling (2017) (157)
- Prognostic Value of Medulloblastoma Extent of Resection After Accounting for Molecular Subgroup: An Integrated Clinical and Molecular Analysis (2016) (156)
- Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations (2018) (154)
- FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma. (2011) (152)
- Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis. (2012) (147)
- Sarcoma classification by DNA methylation profiling (2021) (147)
- TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma (2013) (146)
- Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity (2015) (145)
- Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome (2017) (145)
- Gene expression patterns in ependymomas correlate with tumor location, grade, and patient age. (2003) (144)
- Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes (2019) (139)
- RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival (2012) (129)
- Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes (2010) (128)
- Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis. (2016) (127)
- Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas (2011) (126)
- Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival. (2014) (124)
- The histologic grade is a main prognostic factor for patients with intracranial ependymomas treated in the microneurosurgical era (2004) (121)
- H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers (2017) (121)
- Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort (2014) (120)
- Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial. (2018) (120)
- Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes. (2020) (115)
- Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis (2016) (114)
- Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups. (2018) (113)
- TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma. (2010) (107)
- Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes (2008) (107)
- Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas (2014) (106)
- LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR) (2012) (103)
- Spatial heterogeneity in medulloblastoma (2017) (101)
- HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment (2012) (101)
- Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features (2018) (101)
- Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. (2010) (101)
- A biobank of patient-derived pediatric brain tumor models (2018) (99)
- Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas—Same Entity or First Cousins? (2016) (96)
- Acyl-CoA-Binding Protein Drives Glioblastoma Tumorigenesis by Sustaining Fatty Acid Oxidation. (2019) (94)
- Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme (2017) (90)
- Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations (2018) (88)
- Molecular diagnostics of CNS embryonal tumors (2010) (87)
- Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: an analysis of 168 cases. (1999) (87)
- Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas (2007) (87)
- Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis (2018) (87)
- Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling. (2018) (87)
- MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma (2011) (85)
- Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma (2011) (85)
- Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma (2013) (82)
- A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat (2011) (78)
- Medulloblastoma subgroups remain stable across primary and metastatic compartments (2015) (76)
- The prognostic relevance of molecular alterations in glioblastomas for patients age < 50 years (2005) (76)
- The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis. (2012) (73)
- Immunohistochemical Markers for Prognosis of Ependymal Neoplasms (2002) (71)
- Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma. (2011) (70)
- Biological and clinical heterogeneity of MYCN-amplified medulloblastoma (2012) (70)
- MYCN amplification drives an aggressive form of spinal ependymoma (2019) (70)
- The Molecular Landscape of ETMR at Diagnosis and Relapse (2019) (70)
- Germline Elongator mutations in Sonic Hedgehog medulloblastoma (2020) (69)
- Heterogeneity within the PF-EPN-B ependymoma subgroup (2018) (69)
- Real-time PCR assay based on the differential expression of microRNAs and protein-coding genes for molecular classification of formalin-fixed paraffin embedded medulloblastomas. (2013) (68)
- An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice. (2011) (68)
- Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma. (2010) (67)
- Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma (2015) (64)
- Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course (2019) (64)
- Immunohistochemical markers for intracranial ependymoma recurrence An analysis of 88 cases (2000) (64)
- Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer (2013) (64)
- MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma (2012) (61)
- Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis (2020) (61)
- Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors (2018) (58)
- Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain (2015) (57)
- Clinical utility of fluorescence in situ hybridization (FISH) in nonbrainstem glioblastomas of childhood (2005) (56)
- A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR. (2020) (55)
- Integrated molecular characterization of IDH‐mutant glioblastomas (2018) (55)
- YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis (2019) (54)
- Histology and Molecular Pathology of Pediatric Brain Tumors (2009) (53)
- Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH) (2006) (53)
- Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration (2019) (53)
- Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation. (2019) (53)
- FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma (2016) (52)
- Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma. (2014) (49)
- Isochromosome breakpoints on 17p in medulloblastoma are flanked by different classes of DNA sequence repeats (2006) (49)
- Overcoming multiple drug resistance mechanisms in medulloblastoma (2014) (48)
- Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma (2012) (48)
- Immunohistochemical analysis of p16INK4a, p14ARF, p18INK4c, p21CIP1, p27KIP1 and p73 expression in 271 meningiomas correlation with tumor grade and clinical outcome (2003) (46)
- Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups. (2016) (45)
- Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1‐deficient non‐rhabdoid tumor with favorable long‐term outcome (2017) (45)
- Nestin Expression Identifies Ependymoma Patients with Poor Outcome (2012) (45)
- The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors. (2014) (44)
- FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma (2018) (43)
- WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma (2014) (42)
- Sex differences in oncogenic mutational processes (2019) (41)
- Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis (2017) (41)
- Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort. (2020) (41)
- Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1 (2019) (40)
- Molecular Stratification of Diagnostically Challenging High-Grade Gliomas Composed of Small Cells (2004) (39)
- Telomere dysfunction and chromothripsis (2016) (39)
- HGNET-BCOR Tumors of the Cerebellum: Clinicopathologic and Molecular Characterization of 3 Cases (2017) (38)
- Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions (2019) (35)
- Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells (2017) (35)
- Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype (2015) (35)
- YAP1-fusions in pediatric NF2-wildtype meningioma (2019) (35)
- Immunohistochemical Markers for Prognosis of Average-risk Pediatric Medulloblastomas. The Effect of Apoptotic Index, TrkC, and C-myc Expression (2002) (34)
- Immunohistochemical Markers for Prognosis of Cerebral Glioblastomas (2002) (34)
- Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients (2017) (33)
- The Transcription Factor Evi-1 Is Overexpressed, Promotes Proliferation, and Is Prognostically Unfavorable in Infratentorial Ependymomas (2011) (33)
- Diffuse glioneuronal tumour with oligodendroglioma‐like features and nuclear clusters (DGONC) – a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14 (2019) (33)
- The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma (2018) (32)
- A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors (2017) (32)
- Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma (2016) (31)
- Papillary Tumor of the Pineal Region: A Distinct Molecular Entity (2016) (31)
- Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype (2020) (31)
- Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas (2016) (31)
- Chromosomal imbalances in clear cell ependymomas (2006) (31)
- Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA (2019) (31)
- Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities (2019) (30)
- Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities (2015) (30)
- Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis (2020) (30)
- Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing (2016) (30)
- Telomerase activation in posterior fossa group A ependymomas is associated with dismal prognosis and chromosome 1q gain (2017) (30)
- Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) Are Distinct Entities with Frequent BRAFV600 Mutations (2018) (29)
- p14ARF protein (FL-132) immunoreactivity in intracranial ependymomas and its prognostic significance: an analysis of 103 cases (2001) (29)
- Update on molecular and genetic alterations in adult medulloblastoma (2012) (29)
- The Prognostic Significance of Vascular Endothelial Growth Factor (VEGF C-1) Immunoexpression in Oligodendroglioma. An Analysis of 91 Cases (2000) (29)
- Identification of Gains on 1 q and Epidermal Growth Factor Receptor Overexpression as Independent PrognosticMarkers in Intracranial Ependymoma (2006) (29)
- Tissue Factor Regulation by miR-520g in Primitive Neuronal Brain Tumor Cells: A Possible Link between Oncomirs and the Vascular Tumor Microenvironment. (2016) (29)
- Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations (2019) (29)
- The clinical implications of medulloblastoma (2012) (29)
- Droplet digital PCR is a powerful technique to demonstrate frequent FGFR1 duplication in dysembryoplastic neuroepithelial tumors (2016) (29)
- ETMR: a tumor entity in its infancy (2020) (28)
- Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation (2018) (27)
- Accumulation of genomic aberrations during clinical progression of medulloblastoma (2008) (27)
- Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile (2018) (27)
- Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma (2009) (27)
- Immunohistochemical Markers for Prognosis of Anaplastic Astrocytomas (2002) (26)
- Intraocular Medulloepitheliomas and Embryonal Tumors With Multilayered Rosettes of the Brain: Comparative Roles of LIN28A and C19MC. (2015) (26)
- Recurrent cytogenetic aberrations in central neurocytomas and their biological relevance (2007) (25)
- CSF1R Inhibition Depletes Tumor-Associated Macrophages and Attenuates Tumor Progression in a Mouse Sonic Hedgehog-Medulloblastoma Model (2020) (25)
- DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma (2017) (25)
- Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with loss of morphological but retained genetic key features during progression (2011) (24)
- Pleomorphic Xanthoastrocytomas: Immunohistochemistry, Grading and Clinico-pathologic Correlations. An Analysis of 34 Cases From a Single Institute (2001) (24)
- Prognostic Value of Immunoexpression of the Chemoresistance-related Proteins in Ependymomas: an Analysis of 76 Cases (2004) (24)
- Duplications of KIAA1549 and BRAF screening by Droplet Digital PCR from formalin-fixed paraffin-embedded DNA is an accurate alternative for KIAA1549-BRAF fusion detection in pilocytic astrocytomas (2018) (23)
- Nestin Mediates Hedgehog Pathway Tumorigenesis. (2016) (23)
- Differential nuclear ATRX expression in sarcomas (2016) (22)
- Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors (2021) (22)
- Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
- Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q. (2021) (22)
- Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma (2021) (22)
- Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas. (2021) (22)
- Immunohistochemical Markers for Prognosis of Oligodendroglial Neoplasms (2002) (21)
- Mosaic trisomy of chromosome 1q in human brain tissue associates with unilateral polymicrogyria, very early-onset focal epilepsy, and severe developmental delay (2020) (21)
- Gains at the 1p36 chromosomal region are associated with symptomatic leptomeningeal dissemination of supratentorial glioblastomas. (2007) (21)
- DNA topoisomerase II-alpha and cyclin A immunoexpression in meningiomas and its prognostic significance: an analysis of 263 cases. (2002) (21)
- Molecular approaches to ependymoma: the next step(s). (2012) (21)
- Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B (2021) (20)
- Emerging Insights into the Ependymoma Epigenome (2013) (20)
- Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1) (2021) (20)
- DNA methylation profiling is a method of choice for molecular verification of pediatric WNT-activated medulloblastomas (2018) (19)
- PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum (2021) (19)
- HDAC 5 and HDAC 9 in Medulloblastoma : Novel Markers for Risk Stratification and Role in Tumor Cell Growth (2010) (18)
- Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells. (2019) (18)
- Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation (2018) (17)
- Prognostic value of tumor-associated antigens immunoreactivity and apoptosis in medulloblastomas. An analysis of 73 cases (2006) (17)
- Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma (2012) (15)
- Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors (2016) (15)
- Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1 (2021) (15)
- Subgroup and subtype-specific outcomes in adult medulloblastoma (2021) (15)
- Molecular characterization of medulloblastomas with extensive nodularity (MBEN) (2018) (15)
- Novel oncogene amplifications in tumors from a family with Li–Fraumeni syndrome (2009) (14)
- Long-term survival in a case of ETANTR with histological features of neuronal maturation after therapy (2015) (14)
- Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation (2021) (14)
- Functional loss of a noncanonical BCOR–PRC1.1 complex accelerates SHH-driven medulloblastoma formation (2020) (14)
- Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification (2017) (14)
- An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation (2012) (14)
- The prognostic significance of DNA topoisomerase II-alpha (Ki-S1), p21/Cip-1, and p27/Kip-1 protein immunoexpression in oligodendrogliomas. (2001) (14)
- Sorafenib plus valproic acid for infant spinal glioblastoma. (2010) (13)
- Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas (2021) (13)
- Oligosarcomas, IDH-mutant are distinct and aggressive (2021) (12)
- Quantification of telomere features in tumor tissue sections by an automated 3D imaging-based workflow. (2017) (12)
- Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age (2015) (11)
- Recurrent cytogenetic aberrations in histologically benign, invasive meningiomas of the sphenoid region (2006) (11)
- Spinal metastasis of gliosarcoma: Array-based comparative genomic hybridization for confirmation of metastatic spread (2014) (11)
- Absence of chromosome 19q13.41 amplification in a case of atypical teratoid/rhabdoid tumor with ependymoblastic differentiation (2011) (11)
- Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas (2016) (11)
- Somatostatin receptor subtype 2 (sst2) is a potential prognostic marker and a therapeutic target in medulloblastoma (2013) (11)
- DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region: an international individual patient data meta-analysis (2012) (10)
- Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study. (2021) (10)
- A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair (2014) (10)
- Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker (2019) (10)
- Abstract B73: Second-generation molecular subgrouping of medulloblastoma: An international meta-analysis of Group 3 and Group 4 subtypes (2020) (9)
- Prognostic value of the immunoexpression of chemoresistance‐related proteins in cerebral glioblastomas: An analysis of 168 cases (1999) (9)
- Genetic confirmation that ependymoma can arise as part of multiple endocrine neoplasia type 1 (MEN1) syndrome (2017) (8)
- HIGH GRADE GLIOMAS (2012) (8)
- GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types (2021) (8)
- Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation (2019) (8)
- A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors (2021) (8)
- Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival (2022) (8)
- ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing (2012) (8)
- Immunohistochemical analysis of p18INK4C and p14ARF protein expression in 117 oligodendrogliomas: correlation with tumor grade and clinical outcome. (2009) (8)
- Abstract 3687: An integrative genomics approach identifies distinct molecular and epigenetic subgroups of pediatric glioblastoma (2012) (7)
- Pilocytic Astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response. (2020) (7)
- Identification of a CpG Island Methylator Phenotype (PA-CIMP) in a Subgroup of Pilocytic Astrocytoma (2011) (6)
- Accurate calling of KIAA1549‐BRAF fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data (2020) (6)
- The age of adult pilocytic astrocytoma cells (2021) (6)
- Dissecting telomere maintenance mechanisms in pediatric glioblastoma (2017) (6)
- Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles (2019) (6)
- Integrated molecular analysis of adult Sonic Hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator. (2021) (5)
- Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study (2021) (5)
- CLIN-ONGOING CLINICAL TRIALS (2012) (5)
- Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas (2021) (4)
- NEURO/MEDICAL ONCOLOGY (2013) (4)
- An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data (2020) (4)
- Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model (2021) (4)
- MBCL-07. NON-METASTATIC MEDULLOBLASTOMA OF EARLY CHILDHOOD: RESULTS FROM THE PROSPECTIVE CLINICAL TRIAL HIT-2000 AND AN EXTENDED VALIDATION COHORT (2020) (4)
- Prognostic value of aberrant p53 immunoexpression for the recurrence of ependymoma: An analysis of 76 cases (1999) (4)
- Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability (2021) (4)
- Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts (2022) (4)
- Mapping pediatric brain tumors to their origins in the developing cerebellum (2021) (4)
- NEXT-GENERATION NEUROPATHOLOGY - IMPROVING DIAGNOSTIC ACCURACY FOR BRAIN TUMORS USING DNA METHYLATION ARRAY-BASED MOLECULAR PROFILING (2014) (4)
- The landscape of genomic alterations across childhood cancers (2018) (3)
- Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas (2015) (3)
- Supplemental Information New Brain Tumor Entities Emerge from Molecular Classi fi cation of CNS-PNETs (2016) (3)
- Abstract 3447: FSTL5 improves prognostic subclassification of medulloblastoma (2011) (3)
- Abstract 4347: Medulloblastoma comprises four distinct diseases (2010) (3)
- EMBR-15. DIAGNOSTIC RE-EVALUATION AND POOLED CLINICAL DATA ANALYSIS OF PATIENTS WITH PREVIOUS DIAGNOSIS OF CNS-PNET (2018) (3)
- Medulloepithelioma with peculiar clinical presentation, stem cell phenotype and aberrant DNA-methylation profile. (2015) (3)
- Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells (2019) (3)
- Medulloblastoma and CNS Primitive Neuroectodermal Tumors (2015) (3)
- Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification (2022) (2)
- ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma (2021) (2)
- Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma (2015) (2)
- Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry. (2022) (2)
- The first-in-class ERK inhibitor ulixertinib shows promising activity in MAPK-driven pediatric low-grade glioma models. (2022) (2)
- Molecular subtypes in medulloblastoma: an International meta-analysis for profiles, genetic aberrations, clinicopathological features AND SURVIVAL (2011) (2)
- A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies (2020) (2)
- CNS AT/RTs are a Heterogeneous Entity That Comprises Subgroups with Distinct Molecular Profiles (2014) (2)
- Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases (2022) (2)
- [Immunohistochemical study of neoplasm-associated proteins in cerebellum medulloblastomas]. (1998) (2)
- Molecular progression of SHH-activated medulloblastomas (2019) (2)
- Thrombospondin-1 mimetics are promising novel therapeutics for MYC-associated medulloblastoma (2021) (2)
- Tumorigenesis and Neoplastic Progression The RNA-Binding Protein Musashi 1 Affects Medulloblastoma Growth via a Network of Cancer-Related Genes and Is an Indicator of Poor Prognosis (2012) (2)
- Reply to J.C. Lindsey et al (2011) (2)
- Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses (2023) (2)
- OTHR-41. Amplification of the PLAG family genes – PLAGL1 and PLAGL2 – is a key feature of a novel embryonal CNS tumor type (2022) (1)
- Overcoming multiple drug resistance mechanisms in medulloblastoma (2014) (1)
- EPEN-24. YAP1 FUSION PROTEINS MEDIATE ONCOGENIC ACTIVITY IN EPENDYMOMA VIA INTERACTION WITH TEAD TRANSCRIPTION FACTORS (2018) (1)
- Abstract 1424: KCNJ2 comprises a marker of poor prognosis and a therapeutic target in non-WNT/non-SHH medulloblastoma (2012) (1)
- Omics and Prognostic Markers (2010) (1)
- Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma (2022) (1)
- Abstract 2492: Integrated genomics on molecular subgroups in medulloblastoma (2012) (1)
- DNA Topoisomerase II-α and Cyclin A Immunoexpression in Meningiomas and Its Prognostic Significance (2009) (1)
- Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
- OS6.1 Molecular characterization of astroblastoma (2016) (1)
- [Expression of glial fibrillary acidic protein and protein S-100 in cerebral astrocytic gliomas of varying degrees of malignancy (immunohistochemical study)]. (1995) (1)
- O-9-132 Immunohistochemical study of proliferative activity and P53 oncoprotein expression in different cytological phenotypes of the cerebral glioblastomas (1997) (1)
- LAB-PEDIATRICS LABORATORY RESEARCH (2012) (1)
- [The prognostic importance of cancer-associated proteins and apoptosis in glioblastomas of the cerebral hemispheres]. (1999) (1)
- EPN-30YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE (2016) (1)
- Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial ependymoma (2021) (1)
- Abstract 4872: ICGC PedBrain Tumor - Next-generation sequencing identifies novel subgroup-specific mutations and copy number aberrations in medulloblastoma (2012) (1)
- DNA methylation array-based molecular profiling for brain tumor classification (2015) (1)
- EPEN-06. YAP1 SUBGROUP SUPRATENTORIAL EPENDYMOMA REQUIRES TEAD AND NUCLEAR FACTOR I-MEDIATED TRANSCRIPTIONAL PROGRAMS FOR TUMORIGENESIS (2019) (1)
- NFM-11. PEDIATRIC MENINGIOMAS ARE MOLECULARLY DISTINCT FROM ADULT COUNTERPARTS (2018) (1)
- Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression (2022) (1)
- FAM131B-BRAF Fusion Gene Resulting From 7q34 Deletion Leads to MAPK Pathway Activation in Pilocytic Astrocytoma (2011) (1)
- GENE-12. ANAPLASTIC NEUROEPITHELIAL TUMOR WITH CONDENSED NUCLEI (ANTCON): A NOVEL BRAIN TUMOR ENTITY WITH RECURRENT NTRK FUSION (2019) (1)
- [Proliferative markers of meningiomas: immunohistochemical analysis and prognostic value]. (2002) (1)
- MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS (2014) (1)
- Pilocytic Astrocytomas Mediate Oncogene-Induced Senescence in Sporadic Genetic Aberrations Leading to MAPK Pathway Activation (2012) (1)
- Abstract 5050: KCNJ2 constitutes a marker and therapeutic target of high-risk medulloblastomas. (2013) (1)
- OMICS AND PROGNSTIC MARKERS (2013) (1)
- LGG-20. MOLECULARLY-DEFINED DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR (DLGNT) COMPRISES TWO SUBGROUPS WITH DISTINCT CLINICAL AND GENETIC FEATURES (2018) (0)
- HIP1R and Vimentin immunohistochemistry predict 1p/19q status in IDH-mutant glioma. (2022) (0)
- Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes. (2023) (0)
- Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature (2023) (0)
- Abstract 3453: Induction of differentiation in high-risk ependymoma stem-like cells by treatment with the HDAC inhibitor Vorinostat (2011) (0)
- MODL-11. COMPARISON OF HUMAN & MURINE PA/PXA CHARACTERISTICS (2020) (0)
- MicroRNA Signature Predicts Molecular Risk Groups in Medulloblastoma (2009) (0)
- Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
- Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors (2018) (0)
- MB-18DYSFUNCTION OF THE CHROMATIN REMODELER Chd7 CAUSES ABNORMAL CEREBELLAR DEVELOPMENT AND ACCELERATES MEDULLOBLASTOMA FORMATION. (2016) (0)
- [An immunohistochemical study of the expression of the oncoprotein p53 in astrocytic gliomas of the cerebral hemispheres]. (1996) (0)
- A biobank of patient-derived pediatric brain tumor models (2018) (0)
- Distribution of GOPC:ROS1 and other ROS1 fusions in glioma types (2021) (0)
- Investigation of BRAF fusion genes as a therapeutic target in pilocytic astrocytoma (2012) (0)
- Use of CDK6 oncogene amplification and 17q gain to predict poor clinical risk groups in adult medulloblastoma. (2009) (0)
- PTPS-11ATYPICAL TERATOID/RHABDOID TUMOUR IS AN EPIGENETICALLY HETEROGENEOUS DISEASE CHARACTERIZED BY SUBGROUP SPECIFIC SUPER-ENHANCERS (2015) (0)
- Histone deacetylases 5 and 9 are novel markers for medulloblastoma risk stratification and potential drug targets for therapy (2009) (0)
- WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma (2014) (0)
- Csig-10. Shh-Medulloblastoma Preferentially Arises From Granule Cell Precursors In The Lateral Cerebellum (2016) (0)
- Abstract 1428: A CpG island methylator phenotype defines a clinically aggressive subgroup of posterior fossa ependymoma (2012) (0)
- PNR-12GENOME-WIDE PROFILING OF EMBRYONAL TUMORS WITH MULTILAYERED ROSETTES (ETMR) (2016) (0)
- Em-24. Telomerase Inhibition Induces Growth Arrest in Paediatric Ependymoma (2012) (0)
- Targeting MYC/HDAC2 interaction in Group 3 medulloblastoma – rationales for an innovative therapeutic approach (2015) (0)
- Abstract B71: Molecular heterogeneity and novel oncogenic fusions in RELA- and YAP1-negative supratentorial ependymoma (2020) (0)
- [An immunohistochemical study of the expression of the epithelial antigen Ber-EP4 and other tissue-specific antigens in primary and metastatic brain tumors]. (1998) (0)
- Abstract 3093: Unravelling the biology of aggressive and therapy-resistant embryonal tumors with multilayered rosettes (ETMR) (2014) (0)
- EPEN-28. HETEROGENEITY WITHIN THE PFB EPENDYMOMA SUBGROUP (2018) (0)
- SGK1: a novel prognostic marker and potential drug target in medulloblastoma (2010) (0)
- Clinical outcome following surgical resection and radiotherapy in adult patients with pleomorphic xanthoastrocytoma as defined by DNA methylation profiling (2023) (0)
- PDTM-49. GLOBAL REDUCTION IN H3K27me3, SIMILAR TO H3K27M MUTANT GLIOMAS, IS A MOLECULAR SURROGATE FOR PEDIATRIC POSTERIOR FOSSA- GROUP A EPENDYMOMAS (2017) (0)
- First Results from the International Cancer Genome Consortium PedBrain Tumor Project on Whole-Genome Deep Sequencing in Medulloblastoma (2011) (0)
- LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA (2018) (0)
- Tandem duplications of 7q34 and 3q25 in pilocytic astrocytoma result in RAF fusion genes (2010) (0)
- Abstract 1352: Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors (2018) (0)
- Abstract 509: Genomic profiling of acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link betweenATMmutations and chromothripsis (2017) (0)
- AT-10ATYPICAL TERATOID RHABDOID TUMORS AND POORLY DIFFERENTIATED CHORDOMAS: DISTINCT MOLECULAR ENTITIES WITH SMARCB1/INI1 LOSS AND DISMAL PROGNOSIS (2016) (0)
- EPEN-23. MOLECULAR HETEROGENEITY AMONG PEDIATRIC POSTERIOR FOSSA EPENDYMOMA (2017) (0)
- PL-01. IDENTIFICATION OF NOVEL FUSION GENES IN PEDIATRIC HIGH-GRADE GLIOMA (2012) (0)
- Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
- BIOM-35. CLINICALLY TRACTABLE OUTCOME PREDICTION OF GROUP 3/4 MEDULLOBLASTOMA BASED ON TPD52 IMMUNOHISTOCHEMISTRY: A MULTICOHORT STUDY (2021) (0)
- EPEN-03. ZFTA/C11ORF95 FUSIONS DRIVE SUPRATENTORIAL EPENDYMOMA VIA SHARED ONCOGENIC MECHANISMS (2021) (0)
- EPCT-06. PRECISION ONCOLOGY IN THE PEDIATRIC TARGETED THERAPY 2.0 PROGRAM (2021) (0)
- The molecular landscape of ETMR at diagnosis and relapse (2019) (0)
- Targeting class I histone deacetylases in high risk medulloblastoma – analysis of molecular mechanisms and translational implications (2014) (0)
- GENE-13. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS (2018) (0)
- Abstract 1432: The heterogeneous genomic landscape of posterior fossa ependymoma (2012) (0)
- [An analysis of the interconnections between the proliferative activity of benign and anaplastic astrocytomas of the cerebral hemispheres and their histological structural characteristics]. (1997) (0)
- Actinomycin-D treatment of high-risk ependymomas re-establishes the apoptotic function of p53 (2012) (0)
- Abstract PR02: Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling (2015) (0)
- Abstract 1178: Identification of a novelBRAFfusion partner in pilocytic astrocytoma (2010) (0)
- Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma (2021) (0)
- MEDB-41. Identifying a subgroup of patients with early childhood sonic hedgehog-activated medulloblastoma with unfavorable prognosis after treatment with radiation-sparing regimens including intraventricular methotrexate (2022) (0)
- Abstract 4591: Whole genome sequencing of SHH medulloblastomas predicts molecular groups of responders and non-responders to SMO-inhibition . (2013) (0)
- Progressively Metastasizing Ependymoma: Genomic Aberrations (2012) (0)
- PROLONGED SURVIVAL ASSOCIATED WITH THE USE OF INTRAOPERATIVE CARMUSTINE WAFERS ( GLIADEL w ) IN A PAEDIATRIC PATIENT WITH RECURRENT HIGH GRADE GLIOMA (2012) (0)
- Nestin protein expression is an independent prognostic marker in ependymoma and discriminates WHO II ependymoma with poor outcome (2012) (0)
- Cancer esearch apeutics , Targets , and Chemical Biology e of LIM and SH 3 Protein 1 ( LASP 1 ) in the Metastatic R emination of Medulloblastoma (2010) (0)
- Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions (2023) (0)
- Abstract 3172: Targeting genomic instability in embryonal tumors with multilayered rosettes (ETMR) (2018) (0)
- PATH-03. Clinically Tractable Outcome Prediction of Group 3/4 Medulloblastoma Based on TPD52 Immunohistochemistry: a Multicohort Study (2022) (0)
- Abstract PR08: mSWI/SNF (BAF) complexes facilitate decatentation of DNA by topoisomerase IIα (2013) (0)
- Survival for Medulloblastoma Revealed STK15 as Independent Predictor Microarray-Based Screening for Molecular Markers in (2013) (0)
- EPEN-18. CROSS-SPECIES GENOMICS IDENTIFIES GLI2 AS AN ONCOGENE OF C11orf95 FUSION-POSITIVE SUPRATENTORIAL EPENDYMOMA (2020) (0)
- EMBR-10. GENOMIC COMPLEXITY AND EVOLUTION OF EMBRYONAL TUMORS WITH MULTILAYERED ROSETTES (ETMR) (2018) (0)
- OTHR-32. The Pediatric Targeted Therapy 2.0 registry: robust molecular diagnostics for precision oncology (2022) (0)
- Abstract 4349: The chromosome 17q oncogene LASP1 promotes metastatic dissemination of medulloblastoma (2010) (0)
- Anaplastic pilocytic astrocytoma-an IDH-wildtype diffuse glioma characterized by a distinct DNA methylation profile and combined alterations in MAPK pathway genes, CDKN2A/B and ATRX (2017) (0)
- [An immunohistochemical study of tenascin expression in cerebellar medulloblastomas]. (1997) (0)
- MEDB-60. Medulloblastoma with extensive nodularity mimics cerebellar development and differentiates along the granular precursor lineage (2022) (0)
- Biological and clinical heterogeneity of MYCN-amplified (2012) (0)
- MEDB-14. Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome (2022) (0)
- Recurrent MET fusion genes represent a druggable target in paediatric glioblastoma 1 2 (2016) (0)
- Risk prediction in early childhood SHH medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than two subgroups. (2023) (0)
- The Pediatric Brain Tumor Preclinical Testing Program: update and perspectives (2013) (0)
- [Chromosome 17 abnormalities in medulloblastomas and their prognostic value]. (2008) (0)
- MPTH-15MOLECULAR RECLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS INTO WELL-KNOWN AND NOVEL TUMOR ENTITIES (2015) (0)
- Abstract 4699: Oncogenic fusion genes resulting from 7q34 deletions constitute a novel mechanism of MAPK pathway activation in pilocytic astrocytoma (2011) (0)
- Targeting differentially expressed histone deacetylases in Medulloblastoma – novel approach for treatment of high risk patients (2013) (0)
- Abstract 31: Subgroup-specific molecular alterations may explain the tremendous clinical heterogeneity of intracranial ependymoma (2010) (0)
- HIGH GRADE GLIOMAS AND DIPG (2014) (0)
- MEDU-11. MOLECULAR CHARACTERIZATION OF ETMRs REVEALS A ROLE FOR R-LOOP MEDIATED CHROMOSOMAL INSTABILITY (2019) (0)
- The kinocilia marker WDR16 as a prognostic molecular marker in pediatric ependymoma (2010) (0)
- TBIO-10. PEDIATRIC TARGETED THERAPY 2.0: DEVELOPMENT OF PERSONALIZED PEDIATRIC ONCOLOGY (2018) (0)
- MPTH-26MOLECULAR REFINEMENT OF PEDIATRIC POSTERIOR FOSSA EPENDYMOMA (2015) (0)
- Classifying medulloblastoma into molecular subgroups: Means, motive, and opportunity (2014) (0)
- EMBR-21. CLINICALLY TRACTABLE OUTCOME PREDICTION OF GROUP 3/4 MEDULLOBLASTOMA BASED ON TPD52 IMMUNOHISTOCHEMISTRY: A MULTICOHORT STUDY (2021) (0)
- Corrigendum to: ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma (2021) (0)
- [Immunohistochemical changes in apoptosis in glioblastoma of the cerebral hemispheres]. (1998) (0)
- Characterization of oncogene-induced senescence and the role of the senescence-associated secretory phenotype in pilocytic astrocytoma (2017) (0)
- [Immunohistochemical study of the expression of proliferating cell nuclear antigen in astrocytic gliomas of the cerebral hemispheres]. (1996) (0)
- Abstract 3552: Subgroup-specific pattern of recurrence in medulloblastoma. (2013) (0)
- Functional characterization of novel BRAF fusion gene in pilocytic astrocytomas (2009) (0)
- Molecular outcome prediction in intracranial ependymoma based on WDR16 expression status (2011) (0)
- PDTM-47. CHARACTERIZATION OF THE SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE IN PILOCYTIC ASTROCYTOMA AND ITS ROLE IN ONCOGENE-INDUCED SENESCENCE (2017) (0)
- Spatial and temporal transcriptomics of SHH-medulloblastoma with chromothripsis identifies multiple genetic clones that resist to treatment and lead to relapse (2023) (0)
- GENE-06. DISTINCT MOLECULAR SUBGROUPS OF TUMORS OF THE PINEAL REGION CORRELATE WITH CLINICAL PARAMETERS AND GENETIC ALTERATIONS (2019) (0)
- Abstract LB-B23: Medulloblastoma regulatory circuitries reveal subgroup-specific cellular origins (2015) (0)
- Expression of the kinocilia marker gene WDR16: An indicator of favourable prognosis in pediatric ependymoma (2011) (0)
- RARE-15. Astroblastoma, MN1 altered comprises two molecularly and clinically distinct subgroups defined by the fusion partners BEND2 and CXXC5 (2022) (0)
- Primary intracranial spindle cell sarcoma with RMS-like features share a highly distinct methylation profile and DICER1 mutations (0)
- PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING (2016) (0)
- Abstract A39: Molecular characterization of ETMRs reveals role for R-loop mediated genomic instability and new treatment options (2020) (0)
- MAPK pathway activation in low-grade astrocytomas by BRAF gene duplications and activating mutations (2008) (0)
- ATRT-10. Single-cell transcriptional profiling of ATRTs reveals heterogeneous signatures of tumor and non-malignant cell populations (2022) (0)
- Quantification of telomere features in tumor tissue sections by an automated 3D imaging-based workflow (2016) (0)
- MEDU-21. LOSS OF THE TRANSCRIPTIONAL CO-REPRESSOR BCOR LEADS TO OVEREXPRESSION OF THE GROWTH FACTOR IGF2 AND SHH MEDULLOBLASTOMA TUMOR FORMATION (2019) (0)
- DNA methylation pattern of brain stem pilocytic astrocytomas in children. (2009) (0)
- Functional characterization of SGK1 in medulloblastoma biology (2009) (0)
- MBCL-44. THE MOLECULAR AND CLINICAL LANDSCAPE OF INFANT MEDULLOBLASTOMA (iMB): RESULTS AND MOLECULAR ANALYSIS FROM A PROSPECTIVE, MULTICENTER PHASE II TRIAL (SJYC07) (2018) (0)
- Abstract 3646: (Epi-)genomic homogeneity in radiation-induced glioblastoma with recurrentPDGFRAamplification and loss ofCDKN2A/Bfollowing primary acute lymphatic leukemia and medulloblastoma (2019) (0)
- [Immunohistochemistry characterization of neurocytoma of the cerebral hemispheres]. (1997) (0)
- SGK1 expression predicts treatment response in paediatric medulloblastoma (2009) (0)
- Correction to: Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification (2023) (0)
- EP-03MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS (2015) (0)
- P-3-266 Tenascin immunoreactivityin 78 cerebellar medulloblastomas. Correlation with growth fraction and oncoprotein's expression (1997) (0)
- PDTM-38. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS (2018) (0)
- Identification of SGK1 as a novel predictive marker for treatment response in medulloblastoma. (2009) (0)
- MPTH-23DISTINCT MORPHOLOGY IN MOLECULAR SUBGROUPS OF GLIOBLASTOMA IN YOUNG PATIENTS (2015) (0)
- Identification of Two Molecular and Clinical Distinct Entities of Posterior Fossa Ependymoma (2011) (0)
- Dysregulated expression of histone deacetylases in medulloblastoma - potential targets for selective inhibitor treatment (2013) (0)
- MBCL-21. GERMLINE ELONGATOR MUTATIONS IN SONIC HEDGEHOG MEDULLOBLASTOMA (2020) (0)
- The Pediatric Brain Tumor Preclinical Testing Program: an update on the current status (2012) (0)
- Germline Elongator mutations in Sonic Hedgehog medulloblastoma (2020) (0)
- Abstract 3458: Activated BRAF induces pilocytic astrocytomas in mice (2011) (0)
- THE GENETIC HETEROGENEITY OF POSTERIOR FOSSA EPENDYMOMA (2012) (0)
- P14.03 Adult medulloblastoma: Influence of risk stratification and molecular subtypes on chemotherapy efficacy (2019) (0)
- Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups (2014) (0)
- PNR-23SHH AND WNT SIGNALLING ARE UPREGULATED IN HUMAN INTRAOCULAR MEDULLOEPITHELIOMA AND LEAD TO RETINAL TUMOR-LIKE LESIONS IN THE MOUSE (2016) (0)
- Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
- MBCL-35. CURRENT PROGNOSTIC FACTORS AND TREATMENT RESULTS IN YOUNG CHILDREN MEDULLOBLASTOMAS (2018) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
- MBRS-68. SINGLE NUCLEUS RNA-SEQUENCING DECIPHERS INTRATUMORAL HETEROGENEITY IN MEDULLOBLASTOMA WITH EXTENSIVE NODULARITY (MBEN) (2020) (0)
- [Embryonal neuroepithelial tumors of the cerebral hemispheres]. (1995) (0)
- EMBR-12. IMPROVED DIAGNOSTIC ALGORITHM FOR DIFFERENTIAL DIAGNOSTICS OF CNS EMBRYONAL TUMORS (FORMER CNS-PNET) BY NEUROPATHOLOGICAL RE-EVALUATION OF 256 CASES AND CROSSVALIDATION BY METHYLATION CLASSIFICATION (2018) (0)
- Molecular risk stratification in pediatric medulloblastoma (2007) (0)
- Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities (2019) (0)
- PO-198 FLAVOPEREIRINE SUPPRESSES COLORECTAL CANCER GROWTH VIA INDUCING CELL CYCLE ARREST AND APOPTOSIS IN P53 SIGNALLING DEPENDENCE (2019) (0)
- AT-03ATYPICAL TERATOID/RHABDOID TUMOUR IS A GENETICALLY HOMOGENEOUS BUT EPIGENETICALLY HETEROGENEOUS DISEASE THAT IS DEFINED BY SUBGROUP SPECIFIC SUPER-ENHANCERS (2015) (0)
- Molecular Characterization of Radiation-induced Glioblastoma (2018) (0)
- Abstract 4594: Recurrent FGFR1 hotspot mutations represent a novel therapeutic target in childhood astrocytoma. (2013) (0)
- Personalized pediatric oncology: Targeted Therapy and clinical feasibility (2013) (0)
- PATH-54. MULTI-DIMENSIONAL MOLECULAR CHARACTERIZATION OF PATIENT-MATCHED MEDULLOBLASTOMA AT DIAGNOSIS AND RELAPSE (2019) (0)
- Identification of novel predictive biomarkers and molecular targets in pediatric ependymoma (2009) (0)
- GENOMICS OF MEDULLOBLASTOMA (2010) (0)
- Corrigendum to 'Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry' [Eur J Cancer 180 (2023) 71-84]. (2023) (0)
- Abstract 4124: YAP1 fusion proteins mediate oncogenic activity in ependymoma via interaction with TEAD transcription factors (2018) (0)
- Abstract 4724: Identification of a CpG-island methylator phenotype (CIMP) in a subgroup of pilocytic astrocytoma with favorable prognosis (2011) (0)
- Abstract 3089: (Epi)genetic profiling enables molecular re-classification of CNS-primitive neuroectodermal tumors (2014) (0)
- The Medulloblastoma Methylome Reveals New Epigenetic Regulatory Mechanisms (2013) (0)
- Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival (2022) (0)
- PO-199 Platelet aggregate formation in a novel murine preclinical glioma model depends on podoplanin expression on tumour cells (2018) (0)
- Abstract 2491: Molecular and clinical characterization of the new WHO entity ‘Astroblastoma, MN1 altered’ and its molecular subgroups (2022) (0)
- Abstract 1889: Next-generation neuropathology - Improving diagnostic accuracy for brain tumors using DNA methylation array-based molecular profiling (2014) (0)
- Oncogene-induced senescence and the senescence-associated secretory phenotype in pilocytic astrocytoma (2017) (0)
- Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation (2021) (0)
- Molecular Heterogeneity Among Pediatric Posterior Fossa Ependymomas (2017) (0)
- P09.09 Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas (2016) (0)
- RARE-21. CANCER SPECTRUM IN GERMLINE SUFU MUTATION CARRIERS: A COLLABORATIVE PROJECT OF THE SIOPE HOST GENOME WORKING GROUP (2020) (0)
- ETMR-06. Molecular and clinical characteristics of CNS tumors withBCOR(L1) fusion/internal tandem duplication (2022) (0)
- The Pediatric Brain Tumor Preclinical Testing Program: evaluation of an individualized molecular treatment approach (2011) (0)
- PCM-20PRE-CLINICAL DRUG SCREEN IN A PDX ETMR MOUSE MODEL (2016) (0)
- LGG-06. COMPREHENSIVE GENOMIC CHARACTERIZATION AND INTEGRATED CLINICAL ANALYSIS OF LOW-GRADE GLIOMAS IN CHILDREN WITH NEUROFIBROMATOSIS TYPE 1 (2021) (0)
- SpinalMyxopapillary EpendymomasDemonstrate a Warburg Phenotype (2015) (0)
- Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage (2022) (0)
- Developmental Basis of SHH Medulloblastoma Heterogeneity (2022) (0)
- TRTH-09. PTT2.0: DEVELOPING PERSONALIZED PEDIATRIC ONCOLOGY (2017) (0)
- MBRS-07. BCOR LOSS IMPACTS SHH MEDULLOBLASTOMA FORMATION VIA TRANSCRIPTIONAL UP-REGULATION OF Igf2 (2018) (0)
- MBCL-08. INTEGRATIVE MOLECULAR ANALYSIS OF PATIENT-MATCHED DIAGNOSTIC AND RELAPSED MEDULLOBLASTOMAS (2020) (0)
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What Schools Are Affiliated With Andrey Korshunov?
Andrey Korshunov is affiliated with the following schools:
