Andrius Kazlauskas
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Andrius Kazlauskasbiology Degrees
Biology
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Molecular Biology
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Biochemistry
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Biology
Andrius Kazlauskas's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Andrius Kazlauskas's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase (1995) (2107)
- PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase (1994) (739)
- Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal (1993) (608)
- Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. (2006) (559)
- Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes (1999) (466)
- Regulation of chemotaxis by the platelet-derived growth factor receptor-β (1994) (449)
- c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF. (1999) (438)
- Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins (1989) (431)
- PDGF signaling in cells and mice. (2004) (401)
- Faculty Opinions recommendation of An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. (2010) (303)
- Binding of GAP to activated PDGF receptors. (1990) (292)
- EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3‐kinase. (1996) (278)
- Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. (1994) (277)
- Growth-factor-dependent mitogenesis requires two distinct phases of signalling (2001) (276)
- The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors. (1992) (274)
- Platelet-derived Growth Factor-induced H2O2 Production Requires the Activation of Phosphatidylinositol 3-Kinase* (2000) (249)
- Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo. (1992) (240)
- Phosphoinositide 3-Kinase Regulates Phospholipase Cγ-mediated Calcium Signaling* (1998) (214)
- Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes. (1999) (213)
- GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit (1992) (199)
- Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase. (1990) (198)
- Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively (1993) (198)
- The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. (1993) (190)
- Receptor tyrosine kinases and their targets. (1994) (184)
- Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase. (1999) (184)
- Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase. (1996) (176)
- Phosphatidylinositol 3-Kinase Activity Is Required at a Postendocytic Step in Platelet-derived Growth Factor Receptor Trafficking (*) (1995) (173)
- Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation. (1991) (167)
- Axl is essential for VEGF‐A‐dependent activation of PI3K/Akt (2012) (164)
- Identification of a Putative Syp Substrate, the PDGFβ Receptor (*) (1995) (161)
- PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1 (1999) (150)
- SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors (1992) (147)
- Platelet-derived Growth Factor Receptor-mediated Signal Transduction from Endosomes* (2004) (144)
- Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity (1996) (143)
- Vascular endothelial growth factor and hepatocyte growth factor levels are differentially elevated in patients with advanced retinopathy of prematurity. (2000) (140)
- Lactate Engages Receptor Tyrosine Kinases Axl, Tie2, and Vascular Endothelial Growth Factor Receptor 2 to Activate Phosphoinositide 3-Kinase/Akt and Promote Angiogenesis* (2013) (137)
- A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-γ1 (2003) (135)
- Growth factor‐dependent signaling and cell cycle progression (2001) (134)
- Platelet-derived growth factor plays a key role in proliferative vitreoretinopathy. (1999) (132)
- PDGFs and their receptors. (2017) (125)
- Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42 (1988) (123)
- Is neutralizing vitreal growth factors a viable strategy to prevent proliferative vitreoretinopathy? (2014) (116)
- Full Activation of the Platelet-derived Growth Factor β-Receptor Kinase Involves Multiple Events* (1998) (113)
- Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells. (2005) (112)
- Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation (1995) (108)
- Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells. (2007) (106)
- Protein Kinase A-dependent Translocation of Hsp90α Impairs Endothelial Nitric-oxide Synthase Activity in High Glucose and Diabetes* (2007) (99)
- Platelet-derived growth factor-induced H(2)O(2) production requires the activation of phosphatidylinositol 3-kinase. (2000) (95)
- Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proliferation and Survival of Cells* (2009) (92)
- Recent developments in our understanding of how platelet-derived growth factor (PDGF) and its receptors contribute to proliferative vitreoretinopathy. (2010) (91)
- Identification of the Receptor-associated Signaling Enzymes That Are Required for Platelet-derived Growth Factor-AA-dependent Chemotaxis and DNA Synthesis* (1999) (87)
- Different effects of homo‐ and heterodimers of platelet‐derived growth factor A and B chains on human and mouse fibroblasts. (1988) (87)
- A Role for Src in Signal Relay by the Platelet-derived Growth Factor α Receptor* (1998) (85)
- Hepatocyte growth factor receptor in human RPE cells: implications in proliferative vitreoretinopathy. (1999) (85)
- Bidirectional Signaling Links the Abelson Kinases to the Platelet-Derived Growth Factor Receptor (2004) (83)
- Integrins Enhance Platelet-derived Growth Factor (PDGF)-dependent Responses by Altering the Signal Relay Enzymes That Are Recruited to the PDGF β Receptor* (1999) (83)
- PDGF Receptor-α Does Not Promote HCMV Entry into Epithelial and Endothelial Cells but Increased Quantities Stimulate Entry by an Abnormal Pathway (2012) (82)
- Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling (1995) (82)
- SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans. (2011) (80)
- Platelet‐derived growth factor‐induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCγ (1999) (79)
- Platelet-derived Growth Factor Induces a Long-term Inhibition of N-Methyl-D-aspartate Receptor Function* (1996) (78)
- Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp. (1994) (76)
- A NHERF binding site links the βPDGFR to the cytoskeleton and regulates cell spreading and migration (2004) (74)
- Involvement of Phospholipase D2 in Lysophosphatidate-induced Transactivation of Platelet-derived Growth Factor Receptor-β in Human Bronchial Epithelial Cells* (2003) (74)
- Activation of phospholipase C-gamma is necessary for stimulation of phospholipase D by platelet-derived growth factor. (1994) (73)
- Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit. (1991) (73)
- Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation (1996) (72)
- A role for cadherin-5 in regulation of vascular endothelial growth factor receptor 2 activity in endothelial cells. (1999) (72)
- Connecting signaling and cell cycle progression in growth factor-stimulated cells (2000) (69)
- Pericytes and ocular diseases. (2008) (69)
- A potential role for PDGF-C in experimental and clinical proliferative vitreoretinopathy. (2007) (68)
- Attenuation of experimental proliferative vitreoretinopathy by inhibiting the platelet-derived growth factor receptor. (2000) (68)
- Requirement of phosphatidylinositol-3 kinase for activation of JNK/SAPKs by PDGF. (1997) (67)
- Src-like adaptor protein (Slap) is a negative regulator of mitogenesis (1998) (67)
- Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling. (1998) (65)
- Oxysterol and Diabetes Activate STAT3 and Control Endothelial Expression of Profilin-1 via OSBP1* (2008) (65)
- Src Family Kinases Negatively Regulate Platelet-derived Growth Factor α Receptor-dependent Signaling and Disease Progression* (2000) (65)
- Pathological Signaling via Platelet-Derived Growth Factor Receptor α Involves Chronic Activation of Akt and Suppression of p53 (2011) (65)
- Corneal Graft Rejection Is Accompanied by Apoptosis of the Endothelium and Is Prevented by Gene Therapy With Bcl‐xL (2007) (64)
- Growth factors outside the PDGF family drive experimental PVR. (2009) (64)
- Attenuated Expression of Profilin-1 Confers Protection From Atherosclerosis in the LDL Receptor–Null Mouse (2007) (64)
- PDGF receptors are activated in human epiretinal membranes. (2007) (63)
- N-acetylcysteine suppresses retinal detachment in an experimental model of proliferative vitreoretinopathy. (2010) (60)
- An in vivo gene therapy approach for experimental proliferative vitreoretinopathy using the truncated platelet-derived growth factor alpha receptor. (2002) (60)
- The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways. (2001) (60)
- Disruption of Gap Junctional Communication by the Platelet-derived Growth Factor Is Mediated via Multiple Signaling Pathways* (1999) (58)
- Anti-apoptotic gene therapy prolongs survival of corneal endothelial cells during storage (2011) (57)
- Multiple roles for Src in a PDGF-stimulated cell. (1999) (56)
- A novel strategy to develop therapeutic approaches to prevent proliferative vitreoretinopathy. (2011) (56)
- Roles of platelet-derived growth factor in the developing and mature nervous systems (1997) (55)
- Phosphatidylinositol (3,4,5)-trisphosphate specifically interacts with the phox homology domain of phospholipase D1 and stimulates its activity (2005) (54)
- Activation of Src Family Members Is Not Required for the Platelet-Derived Growth Factor β Receptor To Initiate Mitogenesis (1998) (54)
- Heat Shock Protein 90&agr;–Dependent Translocation of Annexin II to the Surface of Endothelial Cells Modulates Plasmin Activity in the Diabetic Rat Aorta (2004) (53)
- Vascular Endothelial Growth Factor A Competitively Inhibits Platelet-Derived Growth Factor (PDGF)-Dependent Activation of PDGF Receptor and Subsequent Signaling Events and Cellular Responses (2012) (52)
- Platelet-derived Growth Factor-dependent Cellular Transformation Requires Either Phospholipase Cγ or Phosphatidylinositol 3 Kinase* (1997) (51)
- The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1 (1995) (51)
- Expression of PDGFRα is a determinant of the PVR potential of ARPE19 cells. (2011) (50)
- Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications (2012) (49)
- Insulin-like Growth Factor 1 (IGF-1) Stabilizes Nascent Blood Vessels* (2015) (48)
- Macrophage colony-stimulating factor-induced tyrosine phosphorylation of c-fms proteins expressed in FDC-P1 and BALB/c 3T3 cells (1990) (48)
- Regulating angiogenesis at the level of PtdIns‐4,5‐P2 (2006) (47)
- Profilin-1 Is Expressed in Human Atherosclerotic Plaques and Induces Atherogenic Effects on Vascular Smooth Muscle Cells (2010) (47)
- Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a nonangiogenic blinding disease. (2013) (43)
- The role of cathepsins in ocular physiology and pathology. (2007) (41)
- Phospholipase Cγ Activation Drives Increased Production of Autotaxin in Endothelial Cells and Lysophosphatidic Acid-Dependent Regression (2010) (39)
- Regulation of Ras signaling by the cell cycle. (2002) (39)
- The PDGF receptor alpha subunit activates p21ras and triggers DNA synthesis without interacting with rasGAP. (1994) (39)
- Src Family Kinases Promote Vessel Stability by Antagonizing the Rho/ROCK Pathway* (2007) (39)
- VE-cadherin increases the half-life of VEGF receptor 2. (2004) (38)
- Profilin acts downstream of LDL to mediate diabetic endothelial cell dysfunction (2004) (38)
- A Reactive Oxygen Species-Mediated, Self-Perpetuating Loop Persistently Activates Platelet-Derived Growth Factor Receptor α (2013) (38)
- PDGF initiates two distinct phases of protein kinase C activity that make unequal contributions to the G0 to S transition (2000) (37)
- Cultured endothelial cells do not respond to a platelet-derived growth-factor-like protein in an autocrine manner. (1985) (36)
- Corneal endothelial cells are protected from apoptosis by gene therapy. (2011) (36)
- Potential lymphangiogenesis therapies: Learning from current antiangiogenesis therapies—A review (2018) (36)
- A novel function of p53: a gatekeeper of retinal detachment. (2012) (36)
- TGFbeta1-dependent contraction of fibroblasts is mediated by the PDGFalpha receptor. (2002) (35)
- A new member of an old family (2000) (33)
- PLC-γ activation is required for PDGF-βR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells (1997) (33)
- Vascular endothelial growth factor acts primarily via platelet-derived growth factor receptor α to promote proliferative vitreoretinopathy. (2014) (33)
- Epitope Specificity Determines Pathogenicity and Detectability of Anti–Platelet‐Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis (2015) (32)
- The Platelet-derived Growth Factor β Receptor Triggers Multiple Cytoplasmic Signaling Cascades That Arrive at the Nucleus as Distinguishable Inputs* (1997) (31)
- Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells. (1996) (31)
- Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. (2008) (29)
- Platelet-derived growth factor receptor is a novel modulator of type A gamma-aminobutyric acid-gated ion channels. (1995) (27)
- New Insights Regarding Vessel Regression (2006) (27)
- Ex vivo adenovirus-mediated gene transfer to corneal graft endothelial cells in mice. (2004) (27)
- VEGF-A engages at least three tyrosine kinases to activate PI3K/Akt (2012) (27)
- Growth factor-dependent signaling and cell cycle progression. (2001) (26)
- Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosis. (2002) (25)
- Age-Related Macular Degeneration-Associated Silent Polymorphisms in HtrA1 Impair Its Ability To Antagonize Insulin-Like Growth Factor 1 (2013) (24)
- RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology (2015) (23)
- Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis. (2005) (23)
- D-3 phosphoinositide metabolism in cells treated with platelet-derived growth factor. (1996) (23)
- PI3K and PLCγ Play a Central Role in Experimental PVR (2002) (23)
- Keratocyte Apoptosis and Failure of Corneal Allografts (2006) (22)
- Platelet-derived growth factor receptor sequences important for binding of src family tyrosine kinases. (1991) (21)
- The alpha-receptor for platelet-derived growth factor confers bone-metastatic potential to prostate cancer cells by ligand- and dimerization-independent mechanisms. (2010) (21)
- Focus on molecules: platelet-derived growth factor C, PDGF-C. (2008) (20)
- Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src. (1999) (19)
- Effect of Overexpression of Protein Kinase Cα on Rat Lacrimal Gland Protein Secretion (2002) (19)
- Effect of overexpression of constitutively active PKCalpha on rat lacrimal gland protein secretion. (2004) (19)
- The role of c-Src in platelet-derived growth factor α receptor internalization (2003) (19)
- Faculty Opinions recommendation of Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. (2002) (18)
- Phosphospecific antibodies reveal temporal regulation of platelet-derived growth factor beta receptor signaling. (1999) (18)
- Development of wound healing models to study TGF&bgr;3's effect on SMA (2017) (18)
- Diabetes Disrupts the Response of Retinal Endothelial Cells to the Angiomodulator Lysophosphatidic Acid (2012) (17)
- PI3K and PLCgamma play a central role in experimental PVR. (2002) (17)
- PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA. (2009) (16)
- Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases (2016) (15)
- Cambogin Is Preferentially Cytotoxic to Cells Expressing PDGFR (2011) (15)
- Early phosphoinositide 3-kinase activity is required for late activation of protein kinase Cepsilon in platelet-derived-growth-factor-stimulated cells: evidence for signalling across a large temporal gap. (2001) (15)
- SU9518 inhibits proliferative vitreoretinopathy in fibroblast and genetically modified Müller cell-induced rabbit models. (2013) (15)
- PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis (2020) (14)
- The Renin-Angiotensin-Aldosterone System (RAAS) is One of the Effectors by Which Vascular Endothelial Growth Factor (VEGF)/anti-VEGF Controls the Endothelial Cell Barrier. (2020) (14)
- Lysophosphatidic acid contributes to angiogenic homeostasis. (2015) (14)
- Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid. (2014) (13)
- Retinal Pigment Epithelium and Müller Progenitor Cell Interaction Increase Müller Progenitor Cell Expression of PDGFRα and Ability to Induce Proliferative Vitreoretinopathy in a Rabbit Model (2012) (13)
- Vascular Endothelial Cell Growth Factor A Acts via Platelet-Derived Growth Factor Receptor α To Promote Viability of Cells Enduring Hypoxia (2016) (12)
- The role of c-Src in platelet-derived growth factor alpha receptor internalization. (2003) (11)
- VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration (2021) (11)
- Reduced receptor expression for platelet‐derived growth factor and epidermal growth factor in dividing mouse lung epithelial cells (1999) (11)
- PLC-gamma activation is required for PDGF-betaR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells. (1997) (11)
- A comparison of the platelet‐derived growth factor‐dependent tyrosine kinase activity in sparse and confluent fibroblasts (1986) (10)
- A novel endoproteolytic processing activity in mitochondria of erythroid cells and the role in heme synthesis. (2000) (10)
- Plakophilin-2 Promotes Activation of Epidermal Growth Factor Receptor (2014) (10)
- Focus on molecules: Akt (PKB). (2011) (10)
- The priming/completion paradigm to explain growth factor-dependent cell cycle progression (2005) (9)
- Growth Factors Outside of the Pdgf Family Employ Ros/sfks to Activate Pdgf Receptor and Thereby Promote Proliferation and Survival of Cells (2009) (9)
- Epitope specificity determines pathogenicity and detectability of anti-PDGFR autoantibodies in systemic (2015) (8)
- PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts (2017) (8)
- Expression of PDGF, VEGF and their receptors in non-small cell lung tumor cell lines. (1996) (8)
- Microenvironment dependent gene expression signatures in reprogrammed human colon normal and cancer cell lines (2018) (8)
- ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity (2017) (7)
- The kinase-inactive PDGF beta-receptor mediates activation of the MAP kinase cascade via the endogenous PDGF alpha-receptor in HepG2 cells. (1996) (7)
- Regression activity that is naturally present in vitreous becomes ineffective as patients develop proliferative diabetic retinopathy (2013) (7)
- Primary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA) (2012) (6)
- POSTURE DISORDERS AND THEIR CAUSES IN RURAL SCHOOLS PUPILS (2016) (6)
- PtdIns-4,5-P2 as a potential therapeutic target for pathologic angiogenesis (2007) (6)
- The Role of the Wnt Pathway in VEGF/Anti-VEGF-Dependent Control of the Endothelial Cell Barrier (2021) (6)
- PDGFRβ plays an essential role in patient vitreous-stimulated contraction of retinal pigment epithelial cells from epiretinal membranes. (2020) (6)
- Comparison of the phosphorylation events in membranes from proliferating vs. quiescent endothelial cells (1987) (6)
- PDGF receptor-modulates metanephric mesenchyme chemotaxis induced by PDGF AA (2009) (5)
- Lymphatic Vessel Regression and Its Therapeutic Applications: Learning From Principles of Blood Vessel Regression (2022) (5)
- [Viral vectors for gene delivery to corneal endothelial cells]. (2011) (5)
- toDistinct Regions ofthePlatelet-Derived GrowthFactor Receptor 1BSubunit (1992) (4)
- Faculty Opinions recommendation of Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity. (2008) (4)
- The timing and extent of activation of diacylglycerol-responsive protein kinase-cs determines their ability to inhibit or promote platelet-derived growth factor-dependent DNA synthesis. (2002) (4)
- A phage display-based approach to investigate abnormal neovessels of the retina. (2012) (4)
- CHAPTER 70 – Signaling by the Platelet-Derived Growth Factor Receptor Family (2003) (3)
- Effect of overexpression of protein kinase C alpha on rat lacrimal gland protein secretion. (2002) (3)
- Long-term follow-up after acute achilles tendon rupture - Does treatment strategy influence functional outcomes? (2019) (3)
- Platelet-Derived Growth Factor (2008) (3)
- Focus on molecules: HtrA1 and neovascular AMD. (2012) (3)
- Platelet-Derived Growth Factor Receptor Family (2004) (3)
- and subsequent signaling events and cellular responses (2012) (3)
- ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity. (2017) (2)
- Regulation of Tyrosine Kinases by Tyrosine Phosphorylation (1991) (2)
- Platelet-derived Growth Factor-dependent Cellular Transformation Requires Either Phospholipase Cg or Phosphatidylinositol 3 Kinase* (1997) (2)
- Epithelial cells promote fibroblast-mediated contraction of collagen gels by secreting bFGF (2013) (2)
- Faculty Opinions recommendation of PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival. (2005) (1)
- Faculty of 1000 evaluation for Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics. (2018) (1)
- Detection of H2O2-mediated phosphorylation of kinase-inactive PDGFRα. (2013) (1)
- Identifying the role of PDGFRα in the fibrotic pathway of TGF-β3 (2016) (1)
- Different effects ofhomo-andheterodimers of platelet-derived growthfactor A andBchains on human andmouse fibroblasts (1988) (1)
- Faculty Opinions recommendation of Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. (2008) (1)
- Automatic image analysis method for quantification of tube formation by endothelial cells in vitro (2010) (1)
- Characteristics of Primary Human Corneal Endothelial Cells (pHCEC) and Immortalized HCEC (iHCEC) Studying Early Apoptosis and Gene Transfer (2009) (1)
- Advances in a gene therapy-based approach to treat proliferative vitreoretinopathy. (2003) (1)
- Endothelial cells do not respond in an autocrine manner to an autologously produced platelet-derived growth factor-like protein (1985) (1)
- of Akt and suppression of p53 (2011) (1)
- Abstract 3124: Platelet-derived growth factor receptor α cooperates with loss of p16/INK4a and p19/ARF to enhance tumorigenesis through the PI3K- and SHP-2-mediated signaling in the brain (2010) (0)
- PLASMIN IS THE MAJOR PROTEASE RESPONSIBLE FOR PLASMIN IS THE MAJOR PROTEASE RESPONSIBLE FOR PROLIFERATIVE VITREORETINOPATHY (2008) (0)
- Faculty Opinions recommendation of Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization. (2005) (0)
- Faculty Opinions recommendation of Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration. (0)
- Expression Of PDGFRα In Retinal Pigment Epithelial Cells Promotes Experimental Proliferative Vitreoretinopathy (2011) (0)
- Abstract 1468: Antagonism of platelet-derived growth factor receptor-α as a potential therapeutic for prostate cancer bone metastases (2010) (0)
- [Pathophysiologic significance of growth factors and new therapeutic concepts in cardiovascular disease]. (1999) (0)
- Faculty Opinions recommendation of VE-PTP inhibition stabilizes endothelial junctions by activating FGD5. (2019) (0)
- Faculty Opinions recommendation of A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure. (2021) (0)
- Faculty Opinions recommendation of Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin α5. (2021) (0)
- The TEL / PDGF b R fusion in chronic myelomonocytic leukemia signals through STAT 5-dependent and STAT 5-independent pathways (2001) (0)
- How the PDGF receptor induces cell proliferation (2007) (0)
- Functions ofthemajortyrosine phosphorylation site of thePDGFreceptor j#subunit (1991) (0)
- A Potential Role for PDGF–CC in Proliferative Vitreoretinopathy (2006) (0)
- Modulation of GABAA receptor function by activation of the platelet-derived growth factor receptor: 20.15 (1995) (0)
- A PDGF–CC/PDGF alpha receptor autocrine loop require Src to elevate collagen 1 mRNA; implication in experimental PVR. (2004) (0)
- A Role of Phosphatidylinoitol 5-Phosphate 4-Kinases in Proliferative Vitreoretinopathy (2015) (0)
- SH2 Domains of the p85cx Subunit of Phosphatidylinositol 3-Kinase Regulate Binding to Growth Factor Receptors (0)
- Development and Characterization of a new Mouse Model of Proliferative Diabetic Retinopathy (2015) (0)
- Comparison of Fibroblasts and RPE Cells for Their Ability to Induce PVR in Rabbits (2007) (0)
- NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells (2023) (0)
- Faculty of 1000 evaluation for A non-canonical Notch complex regulates adherens junctions and vascular barrier function. (2018) (0)
- EFFECT OF OVEREXPRESSION OF PROTEIN KINASE Cα ON RAT LACRIMAL GLAND PROTEIN SECRETION. (2000) (0)
- Src Enhances in vitro Angiogenesis by Promoting Tube Formation and by Attenuating Rho-Dependent Regression (2007) (0)
- Faculty Opinions recommendation of Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy. (2020) (0)
- Phosphorylation sites inthePDGFreceptor with different specificities forbinding GAPandP13kinase in vivo (1992) (0)
- Faculty Opinions recommendation of Targeting β1-integrin inhibits vascular leakage in endotoxemia. (2018) (0)
- The requirement of tyrosines 579 and 581 for maximal ligand-dependent activation of the betaPDGFR is influenced by noncytoplasmic regions of the receptor. (2001) (0)
- Faculty Opinions recommendation of GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood. (2012) (0)
- VEGF Induces Expression of Genes That Either Promote or Limit Relaxation of the Retinal Endothelial Barrier (2023) (0)
- Faculty Opinions recommendation of Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. (2006) (0)
- Table of Contents (1996) (0)
- Editorial Board (2009) (0)
- Influence of art education on improving communication skills of multiple sclerosis (MS) patients (2011) (0)
- Faculty Opinions recommendation of DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. (2012) (0)
- Faculty Opinions recommendation of Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation. (2011) (0)
- Faculty Opinions recommendation of Biomechanical regulation of blood vessel growth during tissue vascularization. (2009) (0)
- Effect of bcl–xl overexpression in donor corneas on survival of corneal allografts in mice. (2004) (0)
- Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced (2009) (0)
- Faculty Opinions recommendation of PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR. (2007) (0)
- Faculty Opinions recommendation of Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. (2002) (0)
- Keratocyte Apoptosis and Failure of Corneal Allografts you. Your matters (2008) (0)
- Preventing Apoptosis in Corneal Endothelial Cells (2005) (0)
- Faculty Opinions recommendation of Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit. (2002) (0)
- Intracellular signaling processes (1998) (0)
- Faculty Opinions recommendation of A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. (2011) (0)
- Anti-Apoptotic Gene Transfer to Corneal Endothelial Cells Leads to Prolonged Survival During Corneal Preservation (2010) (0)
- Faculty Opinions recommendation of Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin. (2005) (0)
- Faculty of 1000 evaluation for Guidance of cell migration by the Drosophila PDGF/VEGF receptor. (2012) (0)
- Faculty Opinions recommendation of Phospholipase Cgamma1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B. (2007) (0)
- Faculty Opinions recommendation of Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. (2006) (0)
- Characterization of the Vitreal Factors Associated With PVR Pathology and Severity (2009) (0)
- Faculty Opinions recommendation of GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion. (2008) (0)
- Oxysterol Drive CRP Expression in Endothelial Cells (2006) (0)
- Correction of 1st MTP-joint arthrodesis with a bow-shaped osteotomy (2018) (0)
- Faculty Opinions recommendation of A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase. (2001) (0)
- Faculty Opinions recommendation of Opposing effects of Elk-1 multisite phosphorylation shape its response to ERK activation. (2017) (0)
- Faculty Opinions recommendation of p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase. (2006) (0)
- AMD-Associated Silent Substitutions in HTRA1 Hijack the Unfolded Protein Response in RPE (2015) (0)
- Diabetic Retinopathy Is Associated With Increased Vascular Stability (2009) (0)
- Faculty Opinions recommendation of Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1. (2002) (0)
- PDGFRα is required for the anti-fibrotic action of TGFβ3 (2015) (0)
- Receptors | Platelet-Derived Growth Factor Receptor Family (2021) (0)
- Faculty Opinions recommendation of Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition. (2021) (0)
- Intravitreal STI571 Inhibits Development of Proliferative Vitreoretinopathy in an Experimental Rabbit Model (2005) (0)
- Faculty Opinions recommendation of Forkhead transcription factors contribute to execution of the mitotic programme in mammals. (2001) (0)
- SU9518 Inhibits Proliferative Vitreoretinopathy (PVR) in a Rabbit Model (2010) (0)
- Faculty Opinions recommendation of Programmed translational readthrough generates antiangiogenic VEGF-Ax. (2014) (0)
- Gene therapy: can we prevent/modulate apoptosis in EC? (2009) (0)
- Faculty Opinions recommendation of Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling. (2020) (0)
- Faculty Opinions recommendation of Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy. (2019) (0)
- Modulation of apoptotic signaling pathways to promote survival of endothelial cells by gene therapy (2010) (0)
- Technical Advance Functional Tyrosine Kinase Inhibitor Profiling A Generally Applicable Method Points to a Novel Role of Platelet-Derived Growth Factor Receptor- (cid:1) in Tuberous Sclerosis (2002) (0)
- A ROS-mediated , self-perpetuating loop persistently activates PDGFR α (2013) (0)
- AMD-associated silent polymorphisms in HtrA1 ameliorate IGF-1 antagonism (2013) (0)
- Faculty Opinions recommendation of LRP: role in vascular wall integrity and protection from atherosclerosis. (2003) (0)
- Faculty Opinions recommendation of Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema. (2019) (0)
- Endothelial Cells Modulates Plasmin Activity in the Diabetic Rat Aorta Dependent Translocation of Annexin II to the Surface of − α Heat Shock Protein 90 (2004) (0)
- Faculty Opinions recommendation of VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation. (2013) (0)
- Faculty Opinions recommendation of A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. (2006) (0)
- Microenvironment dependent gene expression signatures in reprogrammed human colon normal and cancer cell lines (2018) (0)
- Faculty Opinions recommendation of Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span. (2021) (0)
- Abstract 5208: PDGFRα stimulates glioma cell invasion through tyrosine phosphorylation of Dock180 at Y1811 and activation of the Dock180-CrkII-p130cas-Rac1 pathway (2010) (0)
- Faculty Opinions recommendation of RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. (2004) (0)
- Faculty Opinions recommendation of Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation. (2007) (0)
- The Role of Growth Factors Outside of the PDGF Family in Experimental Proliferative Vitreoretinopathy (2008) (0)
- PDGF Receptor-Dependent Collagen Synthesis and its Implications for Proliferative Vitreoretinopathy in a Rabbit Model of the Disease (2003) (0)
- C-gamma 1. receptor signaling by silencing phospholipase suppresses platelet-derived growth factor beta The GTPase-activating protein of Ras (2013) (0)
- Faculty Opinions recommendation of Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier. (2021) (0)
- Faculty Opinions recommendation of Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events. (2018) (0)
- Production of AAV is technically involved , and accommodates only relatively small DNA inserts (2000) (0)
- Faculty Opinions recommendation of Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. (2012) (0)
- Faculty Opinions recommendation of c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis. (2002) (0)
- Erratum (2016) (0)
- Intravitreal STI571 Inhibition of Proliferative Vitreoretinopathy in an Experimental Rabbit Model Is Dose Dependent (2006) (0)
- Faculty Opinions recommendation of Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. (2008) (0)
- Commentary's title: Plakophilin-2 promotes activation of EGFR (2014) (0)
- Gene therapy for corneal graft survival (2007) (0)
- Indirect Activation of PDGF Receptor Alpha Engages a PI3k/Akt/p53-Dependent Pathway That Promotes Cellular Responses Intrinsic to PVR (2010) (0)
- Faculty Opinions recommendation of Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies. (2002) (0)
- Comparison of the phosphorylation events in membranes prepared from proliferating versus quiescent endothelial cells (1986) (0)
- Long term follow-up of patient reported outcomes and objective measures after acute Achilles tendon rupture: preferred surgical treatment vs. preferred functional rehabilitation (2018) (0)
- Faculty Opinions recommendation of Loss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescence. (2006) (0)
- migration to type IV collagen {alpha}2{beta}1-integrin-mediated A2058 tumor cell (Ca2+)i as a potential downregulator of (2010) (0)
- Faculty Opinions recommendation of Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells. (2010) (0)
- Application of art education in the management and reduction of signs of fatigue in women with MS diagnosis (2011) (0)
- The Composition of Pathological Vessels and Changes in the ILM That Are Caused by Oxygen-Induced Retinopathy in Rats (2010) (0)
- Diabetes Activate STAT 3 and Control Endothelial Expression of Profilin-1 via OSBP 1 * (2008) (0)
- Hyperglycemia promotes mitophagy and thereby mitigates hyperglycemia-induced damage. (2022) (0)
- Protein Phosphorylation in Endothelial Cell Membranes: Relationship to Growth Control (1989) (0)
- Faculty Opinions recommendation of Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors. (2005) (0)
- SU9518 Inhibits Proliferative Vitreoretinopathy (PVR) in a Muller Cell Rabbit Model of PVR (2011) (0)
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What Schools Are Affiliated With Andrius Kazlauskas?
Andrius Kazlauskas is affiliated with the following schools:
