Andrzej Pilc

Q: What Schools Are Affiliated With Andrzej Pilc

Andrzej Pilc is affiliated with the following schools: Medical University of Łódź, Jagiellonian University

Andrzej Pilc's AcademicInfluence.com Rankings

Andrzej Pilc

Medical

#3297

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#3762

Historical Rank

Pharmacology

#406

World Rank

#459

Historical Rank

medical Degrees

Andrzej Pilc

Biology

#12956

World Rank

#16467

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Neuroscience

#2221

World Rank

#2282

Historical Rank

biology Degrees

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Biology

Andrzej Pilc's Degrees

PhD Pharmacology Jagiellonian University

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Andrzej Pilc's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. (2008) (317)
Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist (2001) (308)
The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies. (2010) (252)
Effect of zinc supplementation on antidepressant therapy in unipolar depression: a preliminary placebo-controlled study. (2003) (229)
Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs. (2007) (219)
Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock. (1985) (212)
Mood disorders: regulation by metabotropic glutamate receptors. (2008) (179)
Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study. (2009) (177)
Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats (2003) (165)
Zinc and depression. An update. (2005) (164)
Antidepressant-like properties of zinc in rodent forced swim test (2001) (160)
Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats (2002) (152)
Antidepressant activity of zinc and magnesium in view of the current hypotheses of antidepressant action. (2008) (143)
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice (2007) (140)
Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats (2004) (133)
The involvement of serotonergic system in the antidepressant effect of zinc in the forced swim test (2009) (127)
Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models (1999) (124)
Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rats (2001) (124)
Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist (2005) (120)
Antidepressant- and anxiolytic-like activity of magnesium in mice (2004) (119)
Enhancement of responsiveness of the central serotonergic system and serotonin-2 receptor density in rat frontal cortex by electroconvulsive treatment. (1981) (117)
Antidepressant-like activity of zinc: further behavioral and molecular evidence (2008) (116)
Chronic antidepressants and GABA "B" receptors: a GABA hypothesis of antidepressant drug action. (1984) (113)
Glutamate-Based Antidepressants: Preclinical Psychopharmacology (2013) (111)
Serum zinc level in depressed patients during zinc supplementation of imipramine treatment. (2010) (106)
mGlu2/3 and mGlu5 receptors: Potential targets for novel antidepressants (2013) (104)
Zinc exhibits an antidepressant-like effect in the forced swimming test in mice. (2000) (96)
Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice (2002) (91)
Glutamate receptor ligands as anxiolytics. (2001) (91)
Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABAA signaling (2004) (91)
The involvement of glutamate in the pathophysiology of depression. (2005) (90)
The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration (2001) (90)
Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs (2009) (89)
GABAergic hypotheses of anxiety and depression: focus on GABA-B receptors. (2005) (88)
LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats (1998) (86)
Depression by chronic electroconvulsive treatment of clonidine hypotherma and [3H]clonidine binding to rat cortical membranes. (1982) (84)
Sipuleucel-T immunotherapy for castration-resistant prostate cancer. A systematic review and meta-analysis (2012) (83)
The involvement of NMDA and AMPA receptors in the mechanism of antidepressant-like action of zinc in the forced swim test (2010) (83)
NMDA/glutamate mechanism of antidepressant-like action of magnesium in forced swim test in mice (2007) (82)
Interaction of zinc with antidepressants in the forced swimming test in mice. (2002) (81)
Functional Selectivity and Antidepressant Activity of Serotonin 1A Receptor Ligands (2015) (78)
Antidepressant‐like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents (2006) (73)
Zinc treatment induces cortical brain-derived neurotrophic factor gene expression. (2004) (72)
Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission (2008) (71)
Zinc, magnesium and NMDA receptor alterations in the hippocampus of suicide victims. (2013) (70)
Tumor necrosis factor-α antibodies (infliximab, adalimumab and certolizumab) in Crohn's disease: systematic review and meta-analysis (2013) (67)
The effectiveness of tofacitinib, a novel Janus kinase inhibitor, in the treatment of rheumatoid arthritis: a systematic review and meta-analysis (2013) (63)
Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression. (2001) (62)
Chronic electroconvulsive treatment enhances the density of [3H]prazosin binding sites in the central nervous system of the rat (1983) (60)
Combined administration of PHCCC, a positive allosteric modulator of mGlu4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant-like effects in rats (2007) (59)
Neuroprotective effects of metabotropic glutamate receptor group II and III activators against MPP(+)-induced cell death in human neuroblastoma SH-SY5Y cells: The impact of cell differentiation state (2014) (59)
Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats (2002) (59)
Activation of alpha-2 adrenergic receptors augments neurotransmitter-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices. (1986) (59)
A Qualitative Approach to a Better Understanding of the Problems Underlying Drug Shortages, as Viewed from Belgian, French and the European Union’s Perspectives (2015) (58)
Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus (2002) (57)
Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia (2011) (57)
Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice (2002) (57)
Attenuation by chronic imipramine treatment of [3H]clonidine binding to cortical membranes and of clonidine-induced hypothermia: the influence of central chemosympathectomy (1982) (56)
Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials (2020) (56)
On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039 (2010) (56)
Antibiotic consumption and antimicrobial resistance in Poland; findings and implications (2018) (56)
Roles of group II metabotropic glutamate receptors in modulation of seizure activity (2000) (56)
On the role of metabotropic glutamate receptors in the mechanisms of action of antidepressants. (2002) (55)
Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats. (2002) (55)
The anxiolytic-like effect of metabotropic glutamate receptor antagonists after intrahippocampal injection in rats. (1997) (54)
Effects of South African traditional medicine in animal models for depression. (2008) (54)
An influence of ligands of metabotropic glutamate receptor subtypes on parkinsonian-like symptoms and the striatopallidal pathway in rats (2007) (54)
Time course of zinc deprivation-induced alterations of mice behavior in the forced swim test. (2012) (54)
Enhancement of antidepressant-like activity by joint administration of imipramine and magnesium in the forced swim test: Behavioral and pharmacokinetic studies in mice (2005) (54)
Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems (2010) (53)
Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats. (2004) (53)
Effects of acute and chronic treatment with magnesium in the forced swim test in rats. (2005) (51)
Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment. (2016) (51)
MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats (2005) (50)
Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents (2008) (50)
In vitro and in vivo characterization of MPEP, an allosteric modulator of the metabotropic glutamate receptor subtype 5: Review article (2002) (48)
Zinc-induced adaptive changes in NMDA/glutamatergic and serotonergic receptors. (2009) (48)
NMDA but not AMPA glutamatergic receptors are involved in the antidepressant-like activity of MTEP during the forced swim test in mice. (2010) (48)
Comparative effectiveness of abatacept, apremilast, secukinumab and ustekinumab treatment of psoriatic arthritis: a systematic review and network meta-analysis (2017) (48)
Activation of the NMDA/glutamate receptor complex antagonizes the NMDA antagonist-induced antidepressant-like effects in the forced swim test. (2007) (48)
In the Amygdala Anxiolytic Action of mGlu5 Receptors Antagonist MPEP Involves Neuropeptide Y but not GABAA Signaling (2004) (47)
The Antidepressant-Like Action of Metabotropic Glutamate 7 Receptor Agonist N,N′-Bis(Diphenylmethyl)-1,2-Ethanediamine (AMN082) Is Serotonin-Dependent (2010) (46)
NMDA antagonists under investigation for the treatment of major depressive disorder (2014) (46)
Zinc deficiency in rats is associated with up-regulation of hippocampal NMDA receptor (2015) (46)
Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice (2000) (46)
Investigational NMDA receptor modulators for depression (2012) (45)
The influence of group III metabotropic glutamate receptor stimulation by (1S,3R,4S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid on the parkinsonian-like akinesia and striatal proenkephalin and prodynorphin mRNA expression in rats (2007) (45)
Efficacy and safety of intranasal esketamine for the treatment of major depressive disorder (2020) (45)
The role of glutamate receptors in antipsychotic drug action (2000) (44)
Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu4 receptor (2013) (44)
Effect of MPEP treatment on brain-derived neurotrophic factor gene expression. (2006) (42)
Activation of the mTOR signaling pathway in the antidepressant-like activity of the mGlu5 antagonist MTEP and the mGlu7 agonist AMN082 in the FST in rats (2014) (41)
The antipsychotic‐like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents (2013) (41)
Reduced potency of zinc to interact with NMDA receptors in hippocampal tissue of suicide victims. (2003) (40)
Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test. (2013) (40)
Alpha up-beta down adrenergic regulation: a possible mechanism of action of antidepressant treatments. (1984) (39)
Anxiolytic-like effects of group I metabotropic glutamate antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) in rats. (2000) (38)
Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region. (1998) (37)
Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling. (2004) (36)
The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems (2009) (36)
Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent (2007) (36)
Postdecapitation convulsions in the rat measured with an Animex motility meter: relation to central alpha-adrenoceptors. (1982) (36)
D-serine, a selective glycine/N-methyl-D-aspartate receptor agonist, antagonizes the antidepressant-like effects of magnesium and zinc in mice. (2008) (35)
Differential effects of NMDA–receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices (2000) (35)
Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats (2016) (34)
The correlation between HTA recommendations and reimbursement status of orphan drugs in Europe (2016) (34)
Zinc deficiency alters responsiveness to antidepressant drugs in mice. (2013) (33)
Olfactory bulbectomy and amitriptyline treatment influences mGlu receptors expression in the mouse brain hippocampus. (2008) (32)
The effect of multiple imipramine administration on monoaminergic systems of the rat brain. (1980) (32)
Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent (2007) (32)
Pharmaceutical Regulation in Central and Eastern European Countries: A Current Review (2017) (32)
Anxiolytic-like effects of group III mGlu receptor ligands in the hippocampus involve GABAA signaling. (2006) (32)
Effects of GABAB receptor ligands in rodent tests of anxiety-like behavior. (2007) (32)
Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex (2007) (32)
Anxiolytic-like activity of zinc in rodent tests. (2011) (32)
The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu2/3 receptor agonist, LY379268, is 5-HT1A dependent (2013) (31)
Effectiveness of fixed-dose combination therapy in hypertension: systematic review and meta-analysis (2018) (31)
The Loss of Glutamate-GABA Harmony in Anxiety Disorders (2011) (31)
The GABAB receptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice (2011) (31)
Does histamine interact with cholinergic neurones in its cataleptogenic action in the rat? (1977) (30)
Efavirenz-Based Regimens in Antiretroviral-Naive HIV-Infected Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2015) (30)
Synergistic interaction between α- and β -adrenergic receptors in rat brain slices: Possible site for antidepressant drug action (1985) (29)
The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT1A signalling (2013) (29)
Lack of the antianxiety-like effect of (S)-3,4-DCPG, an mGlu8 receptor agonist, after central administration in rats. (2005) (28)
Alterations in hippocampal calcium-binding neurons induced by stress models of depression: a preliminary assessment. (2010) (28)
Lack of NMDA–AMPA interaction in antidepressant-like effect of CGP 37849, an antagonist of NMDA receptor, in the forced swim test (2008) (28)
Antidepressant-like effects of scopolamine in mice are enhanced by the group II mGlu receptor antagonist LY341495 (2016) (27)
The role of striatal metabotropic glutamate receptors in Parkinson's disease (2002) (27)
Safety profile of biologic drugs in the therapy of Crohn disease: A systematic review and network meta-analysis. (2016) (26)
Is the mGlu5 receptor a possible target for new antidepressant drugs? (2013) (26)
The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies (2014) (26)
A selective mGlu7 receptor antagonist MMPIP reversed antidepressant-like effects of AMN082 in rats (2013) (26)
mGlu5-GABAB interplay in animal models of positive, negative and cognitive symptoms of schizophrenia (2015) (25)
Effect of chronic antidepressant or electroconvulsive shock treatment on mGLuR1a immunoreactivity expression in the rat hippocampus. (1999) (25)
The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity (2000) (25)
The effect of prolonged imipramine and electroconvulsive shock treatment on calcium/calmodulin-dependent protein kinase II in the hippocampus of rat brain (1999) (24)
Different pattern of changes in calcium binding proteins immunoreactivity in the medial prefrontal cortex of rats exposed to stress models of depression. (2011) (24)
Increase in synaptic hippocampal zinc concentration following chronic but not acute zinc treatment in rats (2006) (24)
Selective group II glutamate metabotropic receptor agonist LY354740 attenuates pentetrazole- and picrotoxin-induced seizures. (1999) (24)
The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent (2013) (24)
Effects of anxiolytic drugs on some behavioral consequences in olfactory bulbectomized rats. (2001) (24)
Reimbursement of Orphan Drugs in Europe in Relation to the Type of Authorization by the European Medicines Agency and the Decision Making Based on Health Technology Assessment (2018) (24)
Chronic treatment with zinc and antidepressants induces enhancement of presynaptic/extracellular zinc concentration in the rat prefrontal cortex (2010) (23)
A role for glutamate in the treatment of anxiety and depression: Focus on group I metabotropic glutamate (mGlu) receptors (2002) (23)
Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test (2012) (23)
A novel mGlu4 selective agonist LSP4-2022 increases behavioral despair in mouse models of antidepressant action (2015) (23)
The involvement of monoaminergic neurotransmission in the antidepressant-like action of scopolamine in the tail suspension test (2017) (22)
Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022 (2016) (22)
The influence of prolonged antidepressant treatment on the changes in cyclic AMP accumulation induced by excitatory amino acids in rat cerebral cortical slices (1995) (21)
Selective mGlu5 receptor antagonist MTEP attenuates naloxone-induced morphine withdrawal symptoms. (2004) (20)
On the mechanism of anti-hyperthermic effects of LY379268 and LY487379, group II mGlu receptors activators, in the stress-induced hyperthermia in singly housed mice (2012) (20)
Neurochemical and behavioral studies on the 5-HT1A-dependent antipsychotic action of the mGlu4 receptor agonist LSP4-2022 (2017) (20)
Opiates and specific receptor binding of [3H]clonidine (1980) (20)
Rapid-eye-movement sleep deprivation inhibits clonidine-induced sedation in rats. (1981) (19)
Health-Related Quality of Life Impairment and Indirect Cost of Crohn’s Disease: A Self-Report Study in Poland (2016) (19)
Simultaneous alterations of brain and plasma serotonin concentrations and liver cytochrome P450 in rats fed on a tryptophan-free diet. (2012) (19)
Neuroprotective effects of mGluR II and III activators against staurosporine- and doxorubicin-induced cellular injury in SH-SY5Y cells: New evidence for a mechanism involving inhibition of AIF translocation (2015) (19)
Chronic antidepressants and GABA synapses (1984) (18)
Role of AMPA receptor stimulation and TrkB signaling in the antidepressant-like effect of ketamine co-administered with a group II mGlu receptor antagonist, LY341495, in the forced swim test in rats. (2019) (18)
Influence of histamine on the serotonergic system of rat brain. (1979) (18)
GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67kDa and increased reelin proteins in the hippocampus (2010) (18)
Safety Profile of Biologic Drugs in the Therapy of Ulcerative Colitis: A Systematic Review and Network Meta‐Analysis (2016) (18)
Glutamate-based anxiolytic ligands in clinical trials (2013) (18)
Negative Allosteric Modulators of mGlu7 Receptor as Putative Antipsychotic Drugs (2018) (18)
Pregabalin for the treatment of social anxiety disorder (2015) (17)
SEPARATION OF ACETYLCHOLINE AND CATECHOLAMINE CONTAINING SYNAPTIC VESICLES FROM BRAIN CORTEX (1977) (17)
Effects of Magnesium Supplementation on Unipolar Depression: A Placebo-Controlled Study and Review of the Importance of Dosing and Magnesium Status in the Therapeutic Response (2018) (17)
The influence of 4-methylhistamine, an agonist of histamine H2 receptors on body temperature in rats (1980) (17)
The Effectiveness of Dimethyl Fumarate Monotherapy in the Treatment of Relapsing-Remitting Multiple Sclerosis: A Systematic Review and Meta-Analysis (2014) (17)
The potential antidepressant action and adverse effects profile of scopolamine co-administered with the mGlu7 receptor allosteric agonist AMN082 in mice (2018) (16)
LY-354740 (Eli Lilly). (2003) (16)
Mutual activation of glutamatergic mGlu4 and muscarinic M4 receptors reverses schizophrenia-related changes in rodents (2018) (16)
Expression of group III metabotropic glutamate receptors in the reproductive system of male mice. (2016) (16)
Glutamate-Based Drug Discovery for Novel Antidepressants (2016) (15)
An indirect comparison of infliximab versus adalimumab or golimumab for active ulcerative colitis (2016) (15)
The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia. (2020) (15)
Safety Profile of Biologic Drugs in the Treatment of Inflammatory Bowel Diseases: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials (2016) (15)
Disease activity, quality of life and indirect costs of psoriatic arthritis in Poland (2016) (14)
Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats (2014) (14)
The influence of electroshock on adrenoceptor function in rat brain cerebral cortex: selectivity for the alpha-adrenoceptor site. (1988) (14)
Antidepressant administration has a differential effect on rat brain alpha 2-adrenoceptor sensitivity to agonists and antagonists. (1986) (14)
The use of citation indicators to identify and support high-quality research in Poland (2008) (13)
New evidences for a role of mGluR7 in astrocyte survival: Possible implications for neuroprotection (2018) (13)
Prolonged administration of antidepressant drugs leads to increased binding of [3H]MPEP to mGlu5 receptors (2014) (13)
Simultaneous activation of muscarinic and GABAB receptors as a bidirectional target for novel antipsychotics (2019) (12)
An in vivo procedure for the selective inactivation of rat brain cerebral cortical α-adrenoceptors using N-ethoxycarbonyl-2-ethoxy1,2-dihydroquinoline (EEDQ) (1989) (12)
Nevirapine-Based Regimens in HIV-Infected Antiretroviral-Naive Patients: Systematic Review and Meta-Analysis of Randomized Controlled Trials (2013) (12)
Antidepressant-like activity of 8-Br-cAMP, a PKA activator, in the forced swim test (2008) (12)
Group III mGlu receptor agonist, ACPT-I, attenuates morphine-withdrawal symptoms after peripheral administration in mice (2009) (12)
(S)-4C3HPG, a mixed group I mGlu receptor antagonist and a group II agonist, administered intrastriatally, counteracts parkinsonian-like muscle rigidity in rats (2001) (12)
Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients (2016) (12)
The striatum as a target for anti-rigor effects of an antagonist of mGluR1, but not an agonist of group II metabotropic glutamate receptors (2002) (12)
Spaced electroconvulsive treatment: effects on responses associated with α2‐ and 5‐HT2–receptors (1983) (12)
Negligible binding of 3H-clonidine to histamine H2 receptor. (1979) (11)
Inhibitory actions of mGlu4 receptor ligands on cocaine-, but not nicotine-, induced sensitizing and conditioning locomotor responses in rats. (2014) (11)
Effectiveness and safety of vedolizumab for treatment of Crohn's disease: a systematic review and meta-analysis (2016) (11)
Tetracycline-Based System for Controlled Inducible Expression of Group III Metabotropic Glutamate Receptors (2015) (11)
Over-the-counter medicine and dietary supplement consumption among academic youth in Poland (2016) (10)
Anxiolytic-like effects of metabotropic glutamate antagonist (RS)-alpha-methylserine-O-phosphate in rats. (1996) (10)
Ionic Glutamate Modulators in Depression (Zinc, Magnesium) (2010) (10)
Depression Viewed as a GABA/Glutamate Imbalance in the Central Nervous System (2012) (10)
Antidepressant treatment influences cyclic AMP accumulation induced by excitatory amino acids in rat brain. (1995) (10)
Two possible binding sites for 3H-clonidine in the rat cerebral cortex. (1979) (9)
Cost-Effectiveness Analysis of Crohn’s Disease Treatment with Vedolizumab and Ustekinumab After Failure of Tumor Necrosis Factor-α Antagonist (2018) (9)
Electroshock-induced increase in [3H]prazosin binding to cortical membranes in reserpinized rats. (1984) (9)
Serotonin transporter and receptor ligands with antidepressant activity as neuroprotective and proapoptotic agents. (2017) (9)
Direct or indirect action of histamine on dopamine metabolism in the rat striatum? (1977) (9)
Serotonin transporter and receptor ligands with antidepressant activity as neuroprotective and proapoptotic agents. (2017) (9)
The usefulness of monitored therapy using Clozapine concentration in the blood serum for determining drug dose in Polish schizophrenic patients. (2016) (9)
Histidine-induced bizarre behaviour in rats: The possible involvement of central cholinergic system (1982) (9)
Reimbursement Status and Recommendations Related to Orphan Drugs in European Countries (2019) (9)
Anxiolytic-like activity of MGS0039, a selective group II mGlu receptor antagonist, is serotonin- and GABA-dependent. (2011) (9)
An interaction of histamine H2-receptor antagonists with the noradrenergic system in rat brain. (1978) (9)
Influence of imipramine treatment on the group I of metabotropic glutamate receptors in CA1 region of hippocampus. (1997) (9)
Depression and schizophrenia viewed from the perspective of amino acidergic neurotransmission: Antipodes of psychiatric disorders (2019) (8)
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible receptor inactivator, as a tool for measurement of alpha 2-adrenoceptor occupancy in vivo. (1992) (8)
Chronic treatment with imipramine: Further functional evidence for the enhanced noradrenergic transmission in flexor reflex activity (1983) (8)
The role of alpha 2-adrenoceptors in the mechanism of action of antidepressant drugs. (1987) (8)
The transparency of published health technology assessment-based recommendations on pharmaceutical reimbursement in Poland (2016) (8)
Histamine content and synthesis in central and pheripheral nerve structures during stress (1975) (8)
The influence of mepyramine and burimamide on histamine induced catalepsy in the rat. (1975) (7)
Application of magnetic resonance diffusion anisotropy imaging for the assessment neuroprotecting effects of MPEP, a selective mGluR5 antagonist, on the rat spinal cord injury in vivo. (2005) (7)
Neurochemical changes underlying schizophrenia-related behavior in a modified forced swim test in mice (2018) (7)
Cost‐Utility Analysis of Infliximab with Standard Care versus Standard Care Alone for Induction and Maintenance Treatment of Patients with Ulcerative Colitis in Poland (2016) (7)
Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland (2017) (7)
Some central effects of impromidine, a potent agonist of histamine H2 receptors (1980) (7)
Cost-Effectiveness Analysis of 1-Year Treatment with Golimumab/Standard Care and Standard Care Alone for Ulcerative Colitis in Poland (2016) (7)
Developments in the discovery and design of intranasal antidepressants (2020) (6)
Possible involvement of mGluR1 together with group II and III mGluRs in ibotenate-stimulated cAMP formation in the rat brain cortical slices. (2000) (6)
Impact of Biologic Treatment of Crohn’s Disease on the Rate of Surgeries and Other Healthcare Resources: An Analysis of a Nationwide Database From Poland (2018) (6)
Stimulation of group II metabotropic glutamate receptors or inhibition of group I ones exerts anxiolytic-like effects in rats (2000) (6)
SupersensitiveΒ-adrenergic receptors are down-regulated in rat brain by mianserin administration (2005) (6)
The enhancement and the inhibition of noradrenaune-induced cyclic amp accumulation in rat brain by stimulation of metabotropic glutamate receptors (1996) (6)
Where do we go next in antidepressant drug discovery? A new generation of antidepressants: a pivotal role of AMPA receptor potentiation and mGlu2/3 receptor antagonism (2022) (6)
Metabotropic Approaches to Anxiety (2010) (5)
The enhancement and the inhibition of noradrenaline-induced cyclic AMP accumulation in rat brain by stimulation of metabotropic glutamate receptors. (1996) (5)
Cost-utility analysis of 1-year treatment with adalimumab/standard care and standard care alone for ulcerative colitis in Poland (2016) (5)
Pretreatment with N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline accelerates the electroshock-induced decrease in density of β-adrenoceptors but not functional downregulation (1990) (5)
Costs related to type 1 and 2 diabetes mellitus in Poland (2006) (5)
Spaced electroconvulsive treatment: effects on responses associated with alpha 2- and 5-HT2-receptors. (1983) (4)
The hyperthermic phase of histamine action in rats. (1980) (4)
Developmental changes in the modulation of cyclic amp accumulation by activation of metabotropic glutamate receptors. (2001) (4)
Reserpinization enhances electroconvulsive treatment effects on cortical α1-adrenoceptors (1988) (4)
MPEP, mGlu5 receptor antagonist, regulates NPYmRNA expression in hippocampal and amygdalar neurons. (2004) (4)
The influence of histamine liberator compound 48/80 on histamine level in sciatic nerve of the rat. (1974) (4)
Intraamygdaloid administration of BIBO 3304 increases water intake and extends anxiolytic effects. (2004) (4)
Synergistic interaction between alpha- and beta-adrenergic receptors in rat brain slices: possible site for antidepressant drug action. (1985) (4)
A bright future of researching AMPA receptor agonists for depression treatment (2012) (4)
Analiza kosztów leczenia powikłań cukrzycy poniesionych przez płatnika w Polsce w 2002 roku (2004) (3)
The attenuation by chronic electroconvulsive treatment of hypothermia induced by histamine H2-receptor stimulants in rats. (1983) (3)
Breast cancer surgery decreases serum brain-derived neurotrophic factor concentrations in middle aged women: relationship to the serum C-reactive protein concentration. (2019) (3)
The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent (2013) (3)
Zinc and mental health. (2011) (3)
Some behavioral effects of histamine H1-, and H2-receptor agonists in rats. (1979) (3)
Vedolizumab Compared with Certolizumab in the Therapy of Crohn Disease: A Systematic Review and Indirect Comparison (2016) (3)
A cost-effectiveness analysis of treatment of diabetic complications in 2002 (2004) (3)
Influence of chronic imipramine administration on the CaM-KII activity in postsynaptic densities and synaptosomal plasma membrane fraction isolated from the rat frontal cortex and hippocampus. (2000) (2)
The action of histamine, histamine H1-and H2-receptor agonists on noradrenaline level in rat brain. (1979) (2)
Antidepressant profile of 9-methyl-2[-3-(4-phenyl-1-piperazinylpropyl)]-1,2,3,4-tetrahydro-beta- carbolin-1-one (B-193). (1989) (2)
Therapeutic drug monitoring of depression – Amplification by magnesium ions (2015) (2)
Systemic Solutions, Legislative And Organizational Frameworks Aimed To Prevent Or Mitigate Drug Shortages In European Countries (2016) (2)
Are pharmacological properties of anticoagulants reflected in pharmaceutical pricing and reimbursement policy? Out-patient treatment of venous thromboembolism and utilization of anticoagulants in Poland. (2014) (2)
Inflammatory bowel diseases (IBD) as public health problem – review of the literature (2016) (2)
Corrigendum to “Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor antagonist does not involve GABAA signaling” [Neuropharmacology 47 (2004) 342–350] (2004) (2)
The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT1A signalling (2013) (2)
The histamine-induced skin reaction in schizophrenic and normal subjects. (1982) (2)
Trans-(±)-1-amino-1, 3-cyclopentanedicarboxylate (trans-ACPD) stimulates cAMP accumulation in rat cerebral cortical slices but not in glial or neuronal cell cultures (1994) (2)
A comparison of norepinephrine stimulated inositol phosphate accumulation in cerebral cortex of the Acomys cahirinus, the laboratory mice and the rat. (1988) (2)
New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties (2021) (1)
The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies (2014) (1)
The mechanism of antipsychotic-like action of the mGlu receptor activators: Focus on GABAergic signaling (2015) (1)
Antidepressant-like activity of metabotropic glutamate receptors (2010) (1)
APPLICATION OF CITICOLINE IN SUPPORTING THERAPY OF SELECTED DISEASES (2022) (1)
Application of the MR Diffusion Anisotropy Imaging for the Assessment of MPEP Neuroprotection Effects on the Rat Spinal Cord Injury in vivo (2002) (1)
Chronic co-treatment of NS398 (COX-2 inhibitor) with MTEP changes strategy of mice in Barnes Maze, through membrane resistance variation (2018) (1)
Catalepsia-like symptoms produced by histidine in rats (1973) (1)
Pharmaco-Electroencephalography-Based Assessment of Antidepressant Drug Efficacy—The Use of Magnesium Ions in the Treatment of Depression (2021) (1)
Polski rynek farmaceutyczny a integracja Europejska (2003) (1)
Metabotropic glutamate receptors (2007) (1)
Role of Neurotoxicity in Depression (2014) (1)
The functional cooperation of 5-HT1A and mGlu4R in HEK-293 cell line (2020) (1)
P.2.c.018 Zinc supplementation enhances the therapeutic response in treatment resistant unipolar depression (2006) (1)
[The role of the cytostatic drugs unit in rationalization of hospital drugs management--the case study and the analysis of drug utilization]. (2014) (1)
Effects of acute mGluR7 PAM on changes in short-time plasticity and mGluR7 levels after chronic treatment with mGluR5 antagonist and COX-2 inhibitor (2018) (1)
The influence of histamine H2-receptor antagonists on monoaminergic systems in rat brain (1979) (1)
P.2.a.005 Chronic co-administration of mGluR5 antagonist (MTEP) with COX-2 inhibitor (NS398) affects DSCAM expression in prefrontal cortex and hippocampus in C57Bl/6J mice (2017) (1)
[Zinc homeostasis and glutamatergic system in the pathogenesis and treatment of depression]. (2001) (1)
Dependence of the lower limit of hydrogen explosivity on the initial temperature of the hydrogen mixture with air (1968) (0)
P.2.a.003 NS-398 potentiates the antidepressant-like effect of MTEP in mice: involvement of pro-inflammatory cytokine pathways in the brain (2017) (0)
P.1.009 Cell synchronisation as a tool to optimise expression of metabotropic glutamate receptors in inducible mammalian expression system (2013) (0)
S.11.02 The possible role of mGluR4 in drug addiction (2016) (0)
Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats (2016) (0)
P.2.a.008 Pro-depressive-like effects of mGlu4 selective agonist LSP4–2022 in mice (2015) (0)
CHANGES IN ALPHA2 - ADRENORECEPTOR DENSITY AFTER CHRONIC TREATMENT WITH IMIPRAMINE (1980) (0)
[Not Available]. (2002) (0)
A possible serotoninergic link in the hypothermic action of histamine (1979) (0)
Synthesis and characterization of novel metabotropic glutamate receptor 2/3 (mGluR2/3) positive allosteric modulator (PAM) (2011) (0)
The anxiolytic effect of CRF in rat brain frontal cortex is prevented by CRF1&2 receptor antagonists (2006) (0)
CHL1 gene expression of human blod lymphocytes as SSRI response biomarker (2013) (0)
Stimulation of group 11 metabotropic glutamate receptors counteracts parkinsonian-like muscle rigidity (1998) (0)
Cell synchronization as a tool to optimize protein expression level of mGlu receptors in applying the inducible expression system (2012) (0)
IP562083 a novel mGluR7 negative allosteric modulator (2015) (0)
Behaviorai effects of repeated treatment with amitriptyline and citalopram in the olfactory buibectomy model of depression in C57BL/6J mice (2005) (0)
Potential antidepressant-like effects of MPEP, a potent, selective and systemically active mGluR5 receptor antagonist (2001) (0)
Modified swim test as a model of depressive-like negative symptoms of schizophrenia: GABAergic and serotonergic signaling (2015) (0)
The involvement of GABAB signalling in the antipsychotic-like action of the novel orthosteric agonist of mGlu4receptor – LSP4 (2016) (0)
P.1.h.011: AMN082, a positive allosteric modulator of the mGlu7 receptor, enhances the antidepressant-like activity of scopolamine in the tail suspension test (2017) (0)
The Loss Od Glutamate-GABA Harmony in Anxiety Disorders: towards the Yin/Yang Based Brain Theory. (2011) (0)
The enhancement of noradrenaline induced cyclic AMP accumulation in rat brain by stimulation of metabotropic glutamate receptors occurs in cerebral cortical slices and is mediated by endogenous adenosine (1995) (0)
Effect of histamine H2-receptor antagonists on concentration of noradrenaline, dopamine, 3,4-dihydroxyphenylacetic acid, serotonin and 5-hydroxyindoleacetic acid in rat brain. (1979) (0)
The antipsychotic activity of mGlu receptor agents, focus on novel allosteric vs. orthosteric agonists of mGlu4 receptors (2016) (0)
Reserpinization enhances electroconvulsive treatment effects on cortical alpha 1-adrenoceptors. (1988) (0)
P.4.01 Effects of group II metabotropic glutamate receptor antagonist, MGS0039 in rodent tests of anxiety-like behaviour (2009) (0)
Metabotropic glutamate receptor ligands as a possible targets for treatment of anxiety and depression (2009) (0)
P.2.12 Interaction between metabotropic glutamate 5 receptors and NPY in the amygdala as a novel mechanism of anxiolysis (2004) (0)
Identification and characterization of new 5-HT7 receptor inverse agonists (2012) (0)
Anxiolytic-like effects of group III mGluR positive modulator PHCCC and agonist ACPT-I injected to the rat hippocampus (2006) (0)
The inhibition and enhancement by excitatory amino acids of noradrenaline-stimulated cyclic AMP accumulation in rat cerebral cortical slices (1995) (0)
The quest for allosteric binding sites in mGluRs group III (2012) (0)
The influence of tryptophan-deficient diet on liver cytochrome P450 (2012) (0)
B12 METABOTROPIC GLUTAMATE RECEPTORS AS POTENTIAL TARGETS OF ANTIPARKINSONIAN THERAPY (2005) (0)
[Clinical efficacy and safety of prolonged use of the valganciclovir for the treatment of cytomegalovirus disease in patients after kidney transplantation]. (2013) (0)
CHANGES IN STRIATAL AND MESOLIMBIC DOPAMINE RECEPTORS AFTER SINGLE IN VIVO ADMINISTRATION OF MORPHINE (1980) (0)
Effect of histidine on the formation of catalepsia-like symptoms in rats. (1973) (0)
The influence of magnesium on the action of the anti-depressant drugs in swim test in mice (2005) (0)
Expression of metabotropic glutamate receptors in mammalian cells as a method for identification of new chemical compounds with drug-like activity (2013) (0)
The role of GABAergic transmission in the behavioral effects of mGlu7 receptor positive modulator, AMN082 (2009) (0)
Potential anxiolytic- and antidepressant-like activity of Dipraglurant (ADX48621), the novel negative allosteric modulator (NAM) of the metabotropic glutamate 5 (mGlu5) receptor (2015) (0)
The influence of LY354740 - an agonist of group-II metabotropic glutamate receptors (mGLuR II) on neuronal apoptosis in primary neurons (2011) (0)
The most frequently cited Polish pharmacologists, physiologists and pathophysiologists (2015) (0)
P.3.c.011 The antipsychotic-like activity of VU152100, a muscarinic M4 receptor positive allosteric modulator, in animal models of schizophrenia (2016) (0)
Wieronska-BehvBrRes-2013-298 (2013) (0)
Potential anti-anxiety effects of gropu II glutamate metabotropic receptor agonists in animal models (1999) (0)
Mutual activation of glutamatergic mGlu4 and muscarinic M4 receptors reverses schizophrenia-related changes in rodents (2018) (0)
P.2.h.004 Antidepressant and antipsychotic-like effects of GABA-B receptor ligands in mGlu7 deficient mice (2010) (0)
THE DIFFERENTIAL EFFECTS OF EXCITATORY AMINO ACIDS ON CYCLIC AMP ACCUMULATION IN RATS, THE INFLUENCE OF PROLONGED ANTIDEPRESSANT TREATMENT (1992) (0)
On the role of group I metabotropic glutamate receptors in the mechanism of action of antidepressant drugs (2001) (0)
Involvement of protein kinase a in the mechanism of antidepressant action (1999) (0)
P.1.009 Co-administration of COX-2 inhibitor NS-398 enhances antidepressant effect of mGluR5 antagonist MTEP in mice (2017) (0)
Metabotropic glutamate receptors counteract muscle rigidity induced by haloperidol (1999) (0)
P.1.g.033 Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of scopolamine in behavioural models of depression (2016) (0)
106-5 Antidepressant treatment influences metabotropic receptors for excitatory amino acids in rat brain (1997) (0)
Design and Synthesis of New Quinazolin-4-one Derivatives with Negative mGlu7 Receptor Modulation Activity and Antipsychotic-Like Properties (2023) (0)
P.3.e.005 The involvement of GABAB receptors in antipsychotic-like effects of positive allosteric modulator of muscarinic acetylcholine M4 receptors (2017) (0)
Anxiolytic-like action of LY487379 after central administration in rats (2011) (0)
The effect of chronic treatment with imipramine, ECS and nifedipine on the beta-adrenergic function in the rat hippocampal slices. (1993) (0)
Influence of mGluR7 gene knockout and behavioral changes which its causes on male mice fertility (2012) (0)
An influence of compounds acting on glutamatergic and noradrenergic receptors on the tremor induced by harmaline; automatic measurements by force plate actimeters (2013) (0)
Anxiolytic-like effects of CGP 36742 an antagonist of GABAB receptors in animal models (2001) (0)
The influence of antidepressant treatments on protein kineses activity in rat brain (1997) (0)
BEHAVIORAL AND BIOCHEMICAL STUDIES ON AZIDOMORPHINES. II. ACTION ON OPIATE AND CATECHOLAMINE RECEPTORS (1980) (0)
Sensitivity to paroxetine-induced inhibition of lymphocyte growth in depressed patients as state marker of depression (2015) (0)
Cataleptogenic doses of morphine suppress 3H-spiroperidol binding to striatal membranes (1982) (0)
Effects of South Africa traditional medicine in animal models of depression (2008) (0)
Metabotropic glutamate receptors PAMs as a novel, potential antipsychotic drugs (2013) (0)
Abstract WP425: Blood Brain Barrier Disruption and Vascular Cognitive Impairment in Early Stages of Heart Failure Development in Tgαq*44 Mice (2016) (0)
Characterization of compound C46: a novel positive allosteric modulator? (2011) (0)
The antagonists of metabotropic glutamate receptors produce anxiolytic-like effects and attenuate morphine abstinence symptoms in animals (1996) (0)
IF270750: Synthesis and pharmacology of novel mGluR4 positive allosteric modulator (2012) (0)
S.28.04 The antidepressant potential of mGluR5 and GABA-B receptor antagonists in rodent models of depression (2010) (0)
Metabotropic glutamate receptors as targets for psychotropic drugs (2013) (0)
The effect of interaction between (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R)-ACPD and noradrenaline on cyclic AMP accumulation: different actions in brain slices, primary glial and neuronal cell cultures. (1995) (0)
The Transparency Of Published Recommendations On Reimbursement Of Health Technologies In Poland (2016) (0)
P.2.g.008 Serum zinc level as potential marker in recurrent depressive disorder (2006) (0)
Validation of HEK-293 cell line as a molecular tool for pharmacological study of mGluR7 receptor (2011) (0)
Changes in group I metabotropic glutamate receptors immunoreactivity in rat hippocampus after electroconvulsive shock (2001) (0)
Point mutation as a strategy for development a new tool in pharmacological research for mGluR7 allosteric modulators (2012) (0)
Potential anti-addictive effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist (2002) (0)
Adjustment of adenylate cyclase [EC 4.6.1.1] activity in HEK293 cells transiently expressing mGluRs group III (2011) (0)
NS398 (COX-2 INHIBITOR) potentiates the antidepressant-like effects of MTEP (MGLUR5 ANTAGONIST): Involvement of 5-HT system (2017) (0)
The evaluation of the role of mGluR7 in neuronal apoptotic processes by usage of AMN082, a selective mGluR7 agonist and mGluR7 knockout-derived cells (2013) (0)
On the mechanism of antidepressant-like activity of mGlu5 allosteric modulators (2013) (0)
On the mechanisms of anxiolytic-like effects of mGlu2/3 receptor agonist LY 379268 and positive modulator LY487379 in stress-induced hyperthermia model in mice (2011) (0)
Searching for a new mGluRs positive allosteric modulators (2013) (0)
mGlu4-dependent reversal of the MK-801-induced cognitive impartment involves 5-HT1A receptors (2012) (0)
P.2.015 An anxiolytic but not antidepressant-like activity of a novel positive modulator of mGlu4 receptor Lu AF21394 (2012) (0)
P.2.25 Anxiolytic-like effects of LY487379 an allosteric modulator of mGlu2 receptors in rats (2009) (0)
Chronic effects of imipramine and nifedipine on the beta-adrenergic function in neuronal and glial primary cultures. (1993) (0)
Characterization of metabotropic receptors for excitatory amino acids which stimulate cyclic AMP accumulation in rat brain (1997) (0)
S.24.04 Inhibitory actions of mGlu4 receptor ligands on cocaine- but not nicotine-induced locomotor responses in rats (2012) (0)
Agonists of mGluRs II/III attenuate the staurosporine-induced toxicity in human neuroblastoma SH-SY5Y cells (2011) (0)
Mechanizmy przetwarzania sygnalu blonowego przy udziale kinaz bialkowych zaleznych od cyklicznych nukleotydow (1997) (0)
Biological drugs in the treatment of ankylosing spondylitis (AS) – systematic review (2016) (0)
Refundacja w wybranych krajach Europy Środkowowschodniej (2004) (0)
"Józef Chlebowczyk - badacz procesów narodotwórczych w Europie XIX i XX wieku", ed. Maria W. Wanatowicz, Katowice 2007 : [recenzja] / Andrzej Pilc. (2010) (0)
Indirect costs of diabetes mellitus in Poland (2006) (0)
Antibiotic consumption and antimicrobial resistance in Poland; findings and implications (2018) (0)
Cost-utility analysis of 1-year treatment with adalimumab/standard care and standard care alone for ulcerative colitis in Poland (2016) (0)
Interakcje układu glutaminianergicznego z cynkiem (2002) (0)
Neurotoxicity in Depression (2021) (0)

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