Angela N. Brooks | Academic Influence

Angela N. Brooks's AcademicInfluence.com Rankings

Angela N. Brooks

Biology

#7838

World Rank

#10817

Historical Rank

Computational Biology

#335

World Rank

#336

Historical Rank

Genetics

#1548

World Rank

#1652

Historical Rank

Molecular Biology

#2245

World Rank

#2279

Historical Rank

biology Degrees

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Biology

Angela N. Brooks's Degrees

PhD Genetics University of California, Berkeley
Masters Biology Stanford University
Bachelors Biology Stanford University

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Why Is Angela N. Brooks Influential?

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According to Wikipedia, Angela Brooks is an Assistant Professor of Biomolecular Engineering at University of California, Santa Cruz. She is a member of the Genomics Institute. Early life and education Brooks watched Gattaca in 1997 and was inspired to study genetics. Brooks studied biology at the University of California, San Diego, where she specialised in bioinformatics. She became interested in alternative splicing, and decided to focus on this for her doctoral studies. She moved to University of California, Berkeley for her graduate program, working with Steven E. Brenner. During her doctorate she worked on Modencode, a project which looked to create an encyclopaedia of the elements in the Drosophila melanogaster genomes. She created JuncBASE , a program which analysed high-throughput sequencing data generated. Brooks was a postdoctoral fellow at the Dana–Farber Cancer Institute, where she worked with Matthew Meyerson. Here she studied the cancerous effects of mutation in U2 small nuclear RNA auxiliary factor 1 and SF3B1. U2AF1 is frequently mutated in adenocarcinoma of the lung and myeloid leukemia, and SF3B1 in lymphoid leukemia.

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Angela N. Brooks's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Streamline upwind/Petrov-Galerkin formulations for convection dominated flows with particular emphasis on the incompressible Navier-Stokes equations (1990) (5181)
Comprehensive molecular profiling of lung adenocarcinoma (2014) (4095)
The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs (2005) (2040)
Evolution of genes and genomes on the Drosophila phylogeny (2007) (1992)
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles (2017) (1706)
Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing (2012) (1620)
Visualizing and interpreting cancer genomics data via the Xena platform (2020) (1395)
Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE (2010) (1211)
Structural Basis for Double-Stranded RNA Processing by Dicer (2006) (952)
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. (2016) (931)
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas (2016) (826)
The Developmental Transcriptome of Drosophila melanogaster (2010) (766)
Finite Element Analysis of Incompressible Viscous Flows by the Penalty Function Formulation (1979) (541)
MULTI-DIMENSIONAL UPWIND SCHEME WITH NO CROSSWIND DIFFUSION. (1979) (519)
Patterns of somatic structural variation in human cancer genomes (2020) (377)
The UCSC Xena Platform for cancer genomics data visualization and interpretation (2018) (370)
A theoretical framework for Petrov-Galerkin methods with discontinuous weighting functions: application to the streamline-upwind procedure. (1982) (336)
Nanopore native RNA sequencing of a human poly(A) transcriptome (2018) (335)
Conservation of an RNA regulatory map between Drosophila and mammals. (2011) (246)
The coupling of alternative splicing and nonsense-mediated mRNA decay. (2007) (236)
Genomic basis for RNA alterations in cancer (2020) (221)
Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns (2018) (212)
Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
High-throughput Phenotyping of Lung Cancer Somatic Mutations. (2016) (157)
A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events (2014) (155)
Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia. (2016) (147)
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. (2014) (136)
Application of hyperspherical coordinates to four‐atom reactive scattering: H2+CN→H+HCN (1990) (105)
A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters (2019) (96)
Genome-wide analysis of alternative pre-mRNA splicing and RNA-binding specificities of the Drosophila hnRNP A/B family members. (2009) (89)
Regulation of alternative splicing in Drosophila by 56 RNA binding proteins (2015) (76)
An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer (2018) (69)
Streamline-upwind/Petrov-Galerkin methods for advection dominated flows. (1980) (68)
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment (2021) (58)
A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. (2019) (55)
MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma. (2017) (55)
Sex differences in oncogenic mutational processes (2019) (41)
A Petrov-Galerkin Finite Element Formulation for Convection Dominated Flows (1981) (39)
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations (2020) (34)
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma (2018) (31)
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation (2017) (30)
Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies. (2018) (28)
Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types (2017) (27)
Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments (2017) (26)
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
Identification and experimental validation of splicing regulatory elements in Drosophila melanogaster reveals functionally conserved splicing enhancers in metazoans. (2011) (18)
Transcriptomic Characterization of SF 3 B 1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia (2016) (18)
Pan-cancer study of heterogeneous RNA aberrations (2017) (16)
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification (2021) (16)
SOX 2 and p 63 colocalize at genetic loci in squamous cell carcinomas (2014) (14)
High-throughput Phenotyping of Lung Cancer Somatic Mutations. (2016) (13)
Cell Painting predicts impact of lung cancer variants (2021) (11)
Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2 (2020) (10)
Streamline upwind formulations for advection-diffusion, Navier-Stokes, and first-order hyperbolic equations. (1982) (10)
A Petrov-Galerkin finite element formulation for systems of conservation laws with special reference to the compressible Euler equations. (1982) (9)
Butler enables rapid cloud-based analysis of thousands of human genomes (2020) (8)
The modENCODE Consortium modENCODE Drosophila Identification of Functional Elements and Regulatory Circuits (2011) (7)
A pan cancer analysis of promoter activity highlights the regulatory role of alternative transcription start sites and their association with noncoding mutations (2017) (5)
ALGORITHM FOR SOLVING THE NAVIER-STOKES EQUATIONS BASED UPON THE STREAMLINE UPWIND/PETROV-GALERKIN FORMULATION. (1984) (5)
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants (2019) (5)
Author Correction: Nanopore native RNA sequencing of a human poly(A) transcriptome (2019) (4)
Transcriptome analysis of alternative splicing-coupled nonsense-mediated mRNA decay in human cells reveals broad regulatory potential (2020) (4)
Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2 (2021) (3)
Breaking down RET breakpoints in lung adenocarcinoma. (2014) (3)
Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes (2022) (3)
Comprehensive Bulk and Single Cell Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia (2015) (3)
SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal. (2022) (2)
SF3B1 Mutation Alters The Selection Of 3' RNA Splice Sites In Chronic Lymphocytic Leukemia (2013) (2)
Abstract SY10-02: Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants (2017) (1)
Identification of cancer drivers from tumor-only RNA-seq with RNA-VACAY (2022) (1)
Distinct MET alterations to induce a common phenotype and to define a MET-driven subset of papillary RCC: Results from the Cancer Genome Atlas (TCGA) Kidney Renal Papillary (KIRP) Working Group. (2015) (1)
Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
Abstract 2466: Identifying confidently measured genes in single pediatric cancer patient samples using RNA sequencing (2017) (1)
Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function (2015) (1)
Nanopore native RNA sequencing of a human poly(A) transcriptome (2019) (0)
Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling (2018) (0)
RNA: Reviewers for Volume 21, 2015. (2015) (0)
Abstract A36: Genome-scale ORF screening to identify modulators of the epithelial-to-mesenchymal transition (2017) (0)
Abstract 5020: A genome-scale ORF screen reveals an alternative splicing program that regulates mesenchymal and stem-like cell states in breast cancer (2017) (0)
Author Correction: Nanopore native RNA sequencing of a human poly(A) transcriptome (2019) (0)
Abstract PR07: Towards precision functional genomics via next-generation functional mapping of cancer variants (2015) (0)
Genomic basis for RNA alterations in cancer (2020) (0)
Genomic basis for RNA alterations in cancer (2020) (0)
Abstract PR08:NF1,MET, andRIT1mutations are RAS-pathway driver events in lung adenocarcinoma (2014) (0)
Abstract B2-21: Identification of somatic RNA splicing alterations in human cancers (2015) (0)
Abstract 3150: Characterizing the effects of somatic mutations in splice factors on the transcriptome. (2013) (0)
Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
Abstract 957: Towards precision functional genomics via next-generation functional mapping of cancer variants (2015) (0)
DeepSea: An efficient deep learning model for single-cell segmentation and tracking of time-lapse microscopy images (2022) (0)
RNA Splicing Regulation in Drosophila melanogaster (2011) (0)
Abstract 389: Integrating diverse transcriptomic alterations to identify cancer-relevant genes (2017) (0)
Title An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer (2018) (0)
Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
Abstract PR12: High-throughput gene expression profiling as a generalizable assay for determination of mutation impact on gene function (2015) (0)
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma (2020) (0)
splicing enhancers in metazoans reveals functionally conserved Drosophila melanogaster elements in Identification and experimental validation of splicing regulatory Material (2011) (0)
Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
mammals and Drosophila Conservation of an RNA regulatory map between Material (2010) (0)
Abstract PR04: High-throughput gene expression profiling as a generalizable assay for determination of mutation impact on gene function (2015) (0)
Abstract 669: Compound heterozygous Sf3b1-K700E mutation and Atm deletion in B cells leads to CLL in mice (2016) (0)
Detection of alternative isoforms of gene fusions from long-read RNA-seq with FLAIR-fusion (2022) (0)
Author Correction: Genomic basis for RNA alterations in cancer (2023) (0)
Abstract 2449: Transcriptome and whole-genome sequencing analysis of a novel murine model of chronic lymphocytic leukemia (2017) (0)
Author response: Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2 (2021) (0)
Nanopore sequencing reveals U2AF1 S34F-associated full-length isoforms (2019) (0)
Visualizing and interpreting cancer genomics data via the Xena platform (2020) (0)
From Human Genetic to Mouse Model: SF3B1 Mutation and its Impact on Chronic Lymphocytic Leukemia (2016) (0)
An expression-based variant impact phenotyping protocol to predict the impact of gene variants in cell lines (2022) (0)
Title Regulation of alternative splicing in Drosophila by 56 RNA binding proteins (2015) (0)
Supplemental Information Transcriptomic Characterization of SF 3 B 1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia (2016) (0)
Author response: An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer (2018) (0)
Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
Abstract 1391: SOX2-p63 interaction and genomic co-localization in squamous cell carcinomas (2014) (0)
Genome-Wide Analysis of a Novel Murine Model of Chronic Lymphocytic Leukemia (2016) (0)

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