Ann F. Chambers
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Engineering Computer Science
Ann F. Chambers's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Ann F. Chambers's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Metastasis: Dissemination and growth of cancer cells in metastatic sites (2002) (3844)
- Changing views of the role of matrix metalloproteinases in metastasis. (1997) (1611)
- Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. (1998) (1188)
- Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices. (1996) (511)
- Role of osteopontin in tumour progression (2004) (434)
- Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. (2002) (425)
- Temporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiency. (2000) (406)
- Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. (2008) (377)
- Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy. (2002) (361)
- Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth. (2010) (361)
- Correlation of Osteopontin Protein Expression and Pathological Stage across a Wide Variety of Tumor Histologies (2004) (353)
- CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis. (1999) (316)
- In vivo MRI of cancer cell fate at the single‐cell level in a mouse model of breast cancer metastasis to the brain (2006) (296)
- Does tumour dormancy offer a therapeutic target? (2010) (294)
- Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. (1997) (292)
- Ineffectiveness of Doxorubicin Treatment on Solitary Dormant Mammary Carcinoma Cells or Late-developing Metastases (2003) (289)
- In vivo magnetic resonance imaging of single cells in mouse brain with optical validation (2006) (287)
- Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis. (2014) (284)
- Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen. (1997) (255)
- MDA-MB-435 and M14 cell lines: identical but not M14 melanoma? (2009) (244)
- Osteopontin expression in a group of lymph node negative breast cancer patients (1998) (231)
- The functional and clinical roles of osteopontin in cancer and metastasis. (2001) (231)
- Steps in tumor metastasis: new concepts from intravital videomicroscopy (1995) (224)
- A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines. (2004) (218)
- Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis. (1999) (215)
- Critical steps in hematogenous metastasis: an overview. (2001) (200)
- Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells (1999) (200)
- Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. (1997) (200)
- Osteopontin expression in lung cancer. (1996) (193)
- Fate of melanoma cells entering the microcirculation: over 80% survive and extravasate. (1995) (184)
- Osteopontin and Its Receptor αvβ3 Integrin Are Coexpressed in the Human Endometrium during the Menstrual Cycle But Regulated Differentially (2001) (184)
- Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. (1994) (181)
- Role of the metastasis-promoting protein osteopontin in the tumour microenvironment (2010) (181)
- Osteopontin and beta 3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro. (1995) (181)
- Tumor dormancy and cancer stem cells: implications for the biology and treatment of breast cancer metastasis. (2006) (177)
- Cancer spread and micrometastasis development: Quantitative approaches for in vivo models (2002) (176)
- Dormancy of Solitary Metastatic Cells (2006) (174)
- Effect of tocotrienols on the growth of a human breast cancer cell line in culture (1995) (169)
- Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma (2006) (168)
- Dynamic heterogeneity: rapid generation of metastatic variants in mouse B16 melanoma cells. (1984) (160)
- Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA. (1994) (157)
- Serial Plasma Osteopontin Levels Have Prognostic Value in Metastatic Breast Cancer (2006) (157)
- β1-Integrin: A Potential Therapeutic Target in the Battle against Cancer Recurrence (2011) (150)
- Molecular biology of breast cancer metastasis: Clinical implications of experimental studies on metastatic inefficiency (2000) (148)
- The Biology of Metastasis to a Sanctuary Site (2007) (148)
- Osteopontin‐induced, integrin‐dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met) (2000) (146)
- Metastatic variants are generated spontaneously at a high rate in mouse KHT tumor. (1982) (144)
- The Role of Osteopontin in Breast Cancer: Clinical and Experimental Studies (2001) (140)
- Ras-responsive genes and tumor metastasis. (1993) (138)
- Notch1 Inhibition Alters the CD44hi/CD24lo Population and Reduces the Formation of Brain Metastases from Breast Cancer (2011) (138)
- Osteopontin (Eta-1) and Fibroblast Growth Factor-2 Cross-Talk in Angiogenesis1 (2003) (135)
- Plasma osteopontin (2002) (133)
- Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways (2003) (132)
- Secreted phosphoprotein mrna is induced during multi‐stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts (1990) (131)
- Osteopontin overexpression in breast cancer: Knowledge gained and possible implications for clinical management (2007) (126)
- Clinical targets for anti-metastasis therapy. (2000) (123)
- Independence of metastatic ability and extravasation: metastatic ras-transformed and control fibroblasts extravasate equally well. (1996) (117)
- Identification of the major phosphoprotein secreted by many rodent cell lines as 2ar/osteopontin: enhanced expression in H-ras-transformed 3T3 cells. (1988) (117)
- Three-dimensional high-frequency ultrasound imaging for longitudinal evaluation of liver metastases in preclinical models. (2005) (117)
- Solitary cancer cells as a possible source of tumour dormancy? (2001) (116)
- Osteopontin and its receptor alphavbeta(3) integrin are coexpressed in the human endometrium during the menstrual cycle but regulated differentially. (2001) (116)
- Site‐directed mutagenesis of the arginine‐glycine‐aspartic acid sequence in osteopontin destroys cell adhesion and migration functions (1995) (110)
- p53 mutation, expression, and DNA ploidy in evolving gliomas: evidence for two pathways of progression. (1994) (110)
- Osteopontin and p53 expression are associated with tumor progression in a case of synchronous, bilateral, invasive mammary carcinomas. (1997) (108)
- Tumour dormancy in breast cancer: an update (2007) (107)
- Transcriptional regulation of osteopontin and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter (2004) (107)
- Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells. (1992) (106)
- Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation (2007) (106)
- Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer. (2006) (105)
- Overcoming obstacles to metastasis ‐ defenses against host defenses: Osteopontin (OPN) as a shield against attack by cytotoxic host cells (1994) (105)
- CORRIGENDUM: Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway (2015) (104)
- Enhanced cell surface CD44 variant (v6, v9) expression by osteopontin in breast cancer epithelial cells facilitates tumor cell migration: Novel post-transcriptional, post-translational regulation (2006) (103)
- Increased expression of cathepsins L and B and decreased activity of their inhibitors in metastatic, ras‐transformed NIH 3T3 cells (1992) (102)
- Pre- and post-translational regulation of osteopontin in cancer (2011) (102)
- Tumor dormancy and metastasis. (2009) (101)
- Functional analysis of bone sialoprotein: identification of the hydroxyapatite-nucleating and cell-binding domains by recombinant peptide expression and site-directed mutagenesis. (2000) (99)
- Osteopontin induces multiple changes in gene expression that reflect the six “hallmarks of cancer” in a model of breast cancer progression (2005) (99)
- Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene. (1999) (99)
- Early steps in hematogenous metastasis of B16F1 melanoma cells in chick embryos studied by high-resolution intravital videomicroscopy. (1992) (98)
- Dietary genistein reduces metastasis in a postsurgical orthotopic breast cancer model. (2005) (97)
- Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlates with the metastatic potential of the cell (1995) (96)
- Beta(3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin. (2003) (95)
- Osteopontin Knockdown Suppresses Tumorigenicity of Human Metastatic Breast Carcinoma, MDA-MB-435 (2006) (94)
- Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth (1994) (93)
- Detection and quantification of circulating tumor cells in mouse models of human breast cancer using immunomagnetic enrichment and multiparameter flow cytometry (2005) (92)
- Differential expression of drug resistance genes and chemosensitivity in glial cell lineages correlate with differential response of oligodendrogliomas and astrocytomas to chemotherapy. (2000) (92)
- Antibodies to different peptides in osteopontin reveal complexities in the various secreted forms (2000) (92)
- Early interactions of cancer cells with the microvasculature in mouse liver and muscle during hematogenous metastasis: videomicroscopic analysis (1993) (90)
- Tumor angiogenesis predicts recurrence in invasive colorectal cancer when controlled for Dukes staging. (1996) (89)
- The role of apoptosis in tumor progression and metastasis. (2003) (89)
- Osteopontin and colon cancer progression (2004) (88)
- Experimental metastatic ability of H-ras-transformed NIH3T3 cells. (1985) (86)
- Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin. (1994) (86)
- In Vivo Inhibition of Growth of Human Tumor Lines by Flavonoid Fractions From Cranberry Extract (2006) (86)
- ras mutation and expression of the ras‐regulated genes osteopontin and cathepsin L in human esophageal cancer (1997) (82)
- Recombinant GST‐human osteopontin fusion protein is functional in RGD‐dependent cell adhesion (1994) (81)
- A model system for studying metastasis using the embryonic chick. (1982) (81)
- The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells (1999) (80)
- Tumor heterogeneity and stability of the metastatic phenotype of mouse KHT sarcoma cells. (1981) (78)
- Clonal heterogeneity, experimental metastatic ability, and p21 expression in H-ras-transformed NIH 3T3 cells. (1988) (78)
- Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo. (2008) (76)
- Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays (2008) (76)
- In Vivo Characterization of Changing Blood-Tumor Barrier Permeability in a Mouse Model of Breast Cancer Metastasis: A Complementary Magnetic Resonance Imaging Approach (2011) (72)
- Activated ras regulates the proliferation/apoptosis balance and early survival of developing micrometastases. (2002) (68)
- Time-Course Characterization of the Computed Tomography Contrast Enhancement of an Iodinated Blood-Pool Contrast Agent in Mice Using a Volumetric Flat-Panel Equipped Computed Tomography Scanner (2006) (68)
- Osteopontin(OPN)-induced increase in human mammary epithelial cell invasiveness is urokinase (uPA)-dependent (2001) (67)
- Intravital videomicroscopy of the chorioallantoic microcirculation: a model system for studying metastasis. (1992) (66)
- Activation of MMP‐2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent (1998) (64)
- Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line (2012) (62)
- Quantification of osteopontin in human plasma with an ELISA: basal levels in pre- and postmenopausal women. (1996) (62)
- Multi-Platform Whole-Genome Microarray Analyses Refine the Epigenetic Signature of Breast Cancer Metastasis with Gene Expression and Copy Number (2010) (62)
- Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis. (1995) (62)
- The metastatic process: basic research and clinical implications. (1999) (62)
- Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells. (1990) (62)
- Sequential steps in hematogenous metastasis of cancer cells studied by in vivo videomicroscopy. (1997) (59)
- Low‐molecular‐weight variants of osteopontin generated by serine proteinases in urine of patients with kidney stones (1996) (59)
- Adhesion of metastatic, ras-transformed NIH 3T3 cells to osteopontin, fibronectin, and laminin. (1993) (59)
- Tumor progression and metastasis in murine D2 hyperplastic alveolar nodule mammary tumor cell lines (2004) (58)
- Nuclear localization of maspin is essential for its inhibition of tumor growth and metastasis (2011) (58)
- Osteopontin Induction of Hyaluronan Synthase 2 Expression Promotes Breast Cancer Malignancy* (2006) (58)
- Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response (2012) (57)
- Osteopontin inhibits inducible nitric oxide synthase activity in rat vascular tissue. (1998) (56)
- Quantification of cancer cell extravasation in vivo (2016) (56)
- Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry (2016) (55)
- A New Model for Lymphatic Metastasis: Development of a Variant of the MDA-MB-468 Human Breast Cancer Cell Line that Aggressively Metastasizes to Lymph Nodes (2005) (55)
- Osteopontin identified as colon cancer tumor progression marker. (2003) (55)
- Specificity of cell-cell interactions in sea urchin embryos. Appearance of new cell-surface determinants at gastrulation. (1977) (54)
- The predictive power of semiquantitative immunohistochemical assessment of p53 and c-erb B-2 in lymph node-negative breast cancer. (1996) (54)
- Surface‐enhanced laser desorption/ionization‐time of flight‐mass spectrometry (SELDI‐TOF‐MS): A new proteomic urinary test for patients with urolithiasis (2004) (53)
- Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1 (2008) (53)
- Integrin VLA-2 (alpha2beta1) function in postextravasation movement of human rhabdomyosarcoma RD cells in the liver. (1996) (52)
- Mapping of functional epitopes of osteopontin by monoclonal antibodies raised against defined internal sequences (2002) (51)
- The thrombin inhibitor Argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms (2008) (50)
- Changes over time of extracellular domain of HER2 (ECD/HER2) serum levels have prognostic value in metastatic breast cancer (2009) (49)
- Non‐RGD domains of osteopontin promote cell adhesion without involving αv integrins (1996) (49)
- Understanding Heterogeneity and Permeability of Brain Metastases in Murine Models of HER2-Positive Breast Cancer Through Magnetic Resonance Imaging: Implications for Detection and Therapy (2015) (49)
- Dynamic heterogeneity and metastasis (1984) (48)
- Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. (1996) (47)
- Micrometastatic disease and metastatic outgrowth: clinical issues and experimental approaches. (2009) (47)
- New dual monoclonal ELISA for measuring plasma osteopontin as a biomarker associated with survival in prostate cancer: clinical validation and comparison of multiple ELISAs. (2009) (47)
- Gene signatures of breast cancer progression and metastasis (2011) (45)
- Palm oil tocotrienols and plant flavonoids act synergistically with each other and with Tamoxifen in inhibiting proliferation and growth of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells in culture. (1997) (45)
- Quantitative genetic analysis of tumor progression (2004) (44)
- BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation (2008) (44)
- Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment. (2009) (44)
- Expression of genes that contribute to proliferative and metastatic ability in breast cancer resected during various menstrual phases (1998) (44)
- Brain metastases of breast cancer. (2006) (43)
- Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis (2019) (43)
- Cancer growth and spread are saltatory and phase-locked to the reproductive cycle through mediators of angiogenesis (2005) (42)
- Role of plasma osteopontin as a biomarker in locally advanced breast cancer. (2015) (42)
- Molecular mechanisms of metastasis (2006) (42)
- Identification of four classes of cell surface antigens appearing at gastrulation in sea urchin embryos. (1978) (42)
- Osteopontin Expression in Normal Skin and Non-melanoma Skin Tumors (2008) (41)
- Alternative splicing of PSP94 (prostatic secretory protein of 94 amino acids) mRNA in prostate tissue. (1995) (41)
- Noninvasive Quantification of Tumor Volume in Preclinical Liver Metastasis Models Using Contrast-Enhanced X-Ray Computed Tomography (2008) (41)
- Effect of anti-fibrinolytic therapy on experimental melanoma metastasis (2008) (40)
- Rapid phenotype variation in cells derived from lung metastases of KHT fibrosarcoma. (1984) (40)
- Ovarian Cancer Biomarkers in Urine (2006) (39)
- Influence of diet on metastasis and tumor dormancy (2008) (39)
- Different patterns of gene expression in ras-resistant and ras-sensitive cells. (1991) (39)
- Concurrent Neoadjuvant Chemotherapy and Radiation Therapy in Locally Advanced Breast Cancer. (2017) (37)
- Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway (2014) (37)
- An emerging role for the nuclear localization of maspin in the suppression of tumor progression and metastasis. (2012) (36)
- Up-regulation of TIMP-1 expression in B16-F10 melanoma cells suppresses their metastatic ability in chick embryo (1992) (36)
- ras-transformed NIH 3T3 cell lines, selected for metastatic ability in chick embryos, have increased proportions of p21-expressing cells and are metastatic in nude mice. (1990) (35)
- Three-dimensional imaging and quantification of both solitary cells and metastases in whole mouse liver by magnetic resonance imaging. (2009) (35)
- BRCA2 inhibition enhances cisplatin‐mediated alterations in tumor cell proliferation, metabolism, and metastasis (2014) (35)
- Differences in the repertoires of basement membrane degrading enzymes in two carcinoma sublines with distinct patterns of site-selective metastasis. (1992) (35)
- New clinical and experimental approaches for studying tumor dormancy: does tumor dormancy offer a therapeutic target? (2008) (34)
- Estrous cycle influences organ-specific metastasis of B16F10 melanoma cells. (2003) (34)
- Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial (2014) (34)
- Assessing cancer cell migration and metastatic growth in vivo in the chick embryo using fluorescence intravital imaging. (2012) (34)
- Human 21T breast epithelial cell lines mimic breast cancer progression in vivo and in vitro and show stage-specific gene expression patterns (2010) (33)
- Coordinate expression of OPN and associated receptors during monocyte/macrophage differentiation of HL‐60 cells (1998) (33)
- Plasma osteopontin levels are predictive of disease stage in patients with transitional cell carcinoma of the bladder (2005) (31)
- Absence of hereditary mutations in exons 5 through 9 of the p53 gene and exon 24 of the neurofibromin gene in families with glioma (1994) (31)
- Preclinical Drug Development Must Consider the Impact on Metastasis (2009) (31)
- A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase. (1994) (31)
- Co-Expression of α9β1 Integrin and VEGF-D Confers Lymphatic Metastatic Ability to a Human Breast Cancer Cell Line MDA-MB-468LN (2012) (30)
- Oncogene transformation and the metastatic phenotype. (1988) (30)
- In Vivo Magnetic Resonance Imaging for Investigating the Development and Distribution of Experimental Brain Metastases due to Breast Cancer. (2012) (29)
- Selection for experimental metastatic ability of heterologous tumor cells in the chick embryo after DNA-mediated transfer. (1984) (29)
- Inhibition of angiogenesis in liver metastases by carboxyamidotriazole (CAI) (2004) (28)
- Inhibition of endogenous hydrogen sulfide production in clear-cell renal cell carcinoma cell lines and xenografts restricts their growth, survival and angiogenic potential. (2015) (28)
- Mapping of the functional microcirculation in vital organs using contrast-enhanced in vivo video microscopy. (2005) (28)
- Tumor dormancy and the role of metastasis suppressor genes in regulating ectopic growth. (2006) (27)
- Preclinical Assessment of Anti-cancer Therapeutic Strategies using in vivo Videomicroscopy (1998) (27)
- Brain metastases from breast cancer: lessons from experimental magnetic resonance imaging studies and clinical implications (2013) (27)
- Therapeutic targets for antimetastatic therapy (2004) (27)
- p53 and ras gene expression in human esophageal cancer and Barrett's epithelium: a prospective study. (1994) (26)
- O6-Methylguanine-DNA Methyltransferase in Tumors and Cells of the Oligodendrocyte Lineage (1995) (26)
- In vivo single scan detection of both iron‐labeled cells and breast cancer metastases in the mouse brain using balanced steady‐state free precession imaging at 1.5 T (2011) (26)
- Expression of osteopontin and HGF/Met in adult soft tissue tumors (2005) (26)
- Someras-transformed cells have increased radiosensitivity and decreased repair of sublethal radiation damage (1990) (25)
- The synthetic triterpenoid CDDO-Imidazolide suppresses experimental liver metastasis (2007) (25)
- Serum bound forms of PSP94 (prostate secretory protein of 94 amino acids) in prostate cancer patients (1999) (25)
- Cyclin A2, a novel regulator of EMT (2014) (25)
- Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases (2006) (24)
- The Role of Osteopontin in the Development of Granulomatous Lesions in Lung (2000) (23)
- Tumour metastasis to the liver, and the roles of proteinases and adhesion molecules: new concepts from in vivo videomicroscopy. (1999) (22)
- TBX3 promotes progression of pre‐invasive breast cancer cells by inducing EMT and directly up‐regulating SLUG (2019) (22)
- New clinical and experimental approaches for studying tumor dormancy: does tumor dormancy offer a therapeutic target? (2008) (22)
- The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer (2016) (21)
- Wild-Type p53 Renders Mouse Astrocytes Resistant to 1,3-Bis(2-chloroethyl)-1-nitrosourea despite the Absence of a p53-dependent Cell Cycle Arrest (1996) (21)
- Osteopontin: Role in Cell Signalling and Adhesion (1995) (21)
- Transforming JB6 cells exhibit enhanced integrin‐mediated adhesion to osteopontin (2000) (20)
- Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization (2018) (20)
- Comparison of metastatic properties of a variety of mouse, rat, and human cells in assays in nude mice and chick embryos. (1990) (20)
- Non-RGD domains of osteopontin promote cell adhesion without involving alpha v integrins. (1996) (19)
- Evaluating Changes to Blood-Brain Barrier Integrity in Brain Metastasis over Time and after Radiation Treatment1 (2016) (19)
- In vivo videomicroscopy reveals differential effects of the vascular-targeting agent ZD6126 and the anti-angiogenic agent ZD6474 on vascular function in a liver metastasis model (2004) (18)
- Experimental Metastasis Assays in the Chick Embryo (2003) (18)
- Expression of Antisense Osteopontin RNA in Metastatic Mouse Fibroblasts Is Associated with Reduced Malignancy (1995) (18)
- Contrast-Enhanced Microcomputed Tomography Using Intraperitoneal Contrast Injection for the Assessment of Tumor-Burden in Liver Metastasis Models (2008) (18)
- Comparative analysis of two alternative first exons reported for the mouse osteopontin gene. (1993) (18)
- Cells transformed with a ts viral src mutant are temperature sensitive for in vivo growth (1985) (17)
- O(6)-methylguanine-DNA methyltransferase activity, p53 gene status and BCNU resistance in mouse astrocytes. (1999) (17)
- Genetic background influences timing, morphology and dissemination of lymphomas in p53-deficient mice. (1998) (17)
- Ex-vivo cellular MRI with b-SSFP: quantitative benefits of 3 T over 1.5 T (2008) (17)
- Radiation-induced lung injury after concurrent neoadjuvant chemoradiotherapy for locally advanced breast cancer (2014) (16)
- Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts (2014) (16)
- Role of osteopontin as a predictive biomarker for anti-EGFR therapy in triple-negative breast cancer (2018) (16)
- Detection of various epitopes of murine osteopontin by monoclonal antibodies. (1999) (15)
- Evaluating the role of serine protease inhibition in the management of tumor micrometastases. (2003) (15)
- Invasion and metastasis—recent advances and future challenges (2015) (15)
- MRI surveillance of cancer cell fate in a brain metastasis model after early radiotherapy (2017) (15)
- Osteopontin expression in salivary gland tumours. (2006) (14)
- Breast cancer metastasis progression as revealed by intravital videomicroscopy (2006) (14)
- Imaging the Impact of Chemically Inducible Proteins on Cellular Dynamics In Vivo (2012) (14)
- Dynamic heterogeneity: characterization of two cell lines derived from experimental lung metastases of mouse KHT fibrosarcoma. (1987) (14)
- Hypoxia promotes tumor cell motility via RhoA and ROCK1 signaling pathways (2014) (12)
- Angiogenesis as a Target for Breast Cancer Therapy (1999) (12)
- Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in mucoepidermoid carcinoma and acinic cell adenocarcinoma of salivary gland origin. (2014) (12)
- Putative growth characteristics of micrometastatic breast cancer (2008) (12)
- Effects of long-chain fatty amines on the growth of ras-transformed NIH 3T3 cells. (1994) (12)
- Technical Note: Immunohistochemical evaluation of mouse brain irradiation targeting accuracy with 3D-printed immobilization device. (2015) (11)
- Anticarcinogenic Activities of Naturally Occurring Cysteine Proteinase Inhibitors (1993) (11)
- CD 44 Variants but not CD 44 s Cooperate with b 1-containing Integrins to Permit Cells to Bind to Osteopontin Independently of Arginine-glycine-aspartic Acid , thereby Stimulating Cell Motility and Chemotaxis 1 (1998) (11)
- Use of NeoR B16F1 murine melanoma cells to assess clonality of experimental metastases in the immune-deficient chick embryo (1988) (10)
- Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in pleomorphic adenoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma. (2013) (10)
- Chapter 9. Intravital videomicroscopy in angiogenesis research. (2008) (9)
- Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host (2018) (9)
- Image analysis of Feulgen-stained transformed NIH 3T3 cells differing in p21 expression and ras-induced metastatic ability. (1994) (9)
- Mechanisms of oncogene-mediated alterations in metastatic ability. (1992) (9)
- Molecular cytogenetic characterization of human breast cancer cell line MDA-MB-468 and its variant 468LN, which displays aggressive lymphatic metastasis. (2008) (9)
- Regulation and Function of Osteopontin in Ras‐Transformed Cells a (1995) (9)
- ras Transfection and expression does not induce progression from tumorigenicity to metastatic ability in mouse LTA cells (1990) (8)
- Half brain irradiation in a murine model of breast cancer brain metastasis: magnetic resonance imaging and histological assessments of dose-response (2018) (7)
- Metastatic NIH 3T3 x LTA cell hybrids express 72 kDa type IV collagenase. (1995) (7)
- Primary melanoma tumor inhibits metastasis through alterations in systemic hemostasis (2016) (7)
- Osteopontin increases breast cancer cell sensitivity to specific signaling pathway inhibitors in preclinical models (2011) (7)
- Compound speckle model detects anti‐angiogenic tumor response in preclinical nonlinear contrast‐enhanced ultrasonography (2017) (7)
- Isoform-specific promotion of breast cancer tumorigenicity by TBX3 involves induction of angiogenesis (2019) (7)
- Gene expression and metastasis of somatic cell hybrids between murine fibroblast cell lines of different malignant potential (1991) (7)
- Cancer dissemination from a physical sciences perspective (2016) (7)
- A Monoclonal Antibody against Osteopontin Inhibits RGD‐Mediated Cell Adhesion to Osteopontin (1995) (7)
- Tumor Dormancy, Metastasis, and Cancer Stem Cells (2009) (6)
- Integrin VLA-2 (a2ßi)Function in Postextravasation Movement of Human Rhabdomyosarcoma RD Cells in the Liver1 (2006) (5)
- Evaluating the effectiveness of cancer drug sensitization in vitro and in vivo. (2015) (5)
- Variability of three-dimensional high-frequency ultrasound measurements of small tumor volumes (2004) (5)
- Modulation of clonal progression in B16F1 melanoma cells (1991) (5)
- MMP-2 expression is associated with, but not sufficient for, malignant conversion of murine LTA cells. (1998) (5)
- BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis (2015) (5)
- Brain Metastasis: Basic Biology, Clinical Management, and Insight From Experimental Model Systems (2017) (4)
- Wild-type p53 renders mouse astrocytes resistant to 1,3-Bis(2-chloroethyl)-1-nitrosourea despite the absence of a p53-dependent cell cycle arrest [corrected]. (1996) (4)
- A method to validate quantitative high-frequency power doppler ultrasound with fluorescence in vivo video microscopy. (2014) (4)
- Famesylamine: An inhibitor of famesylation and growth ofras-transformed cells (1993) (4)
- Contribution of Osteopontin to the Development of Bone Metastasis (2005) (4)
- Prevention of Conversion of Tumor Dormancy into Proliferative Metastases (2016) (4)
- Rates of generation of methotrexate-resistant variants in cells temperature-sensitive for malignant transformation (1988) (4)
- Malignant properties of P635 glioma are independent of glial fibrillary acidic protein expression (1991) (3)
- 578 Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis (2014) (3)
- A compound speckle model for vascular complexity quantification in nonlinear contrast-enhanced ultrasonography (2014) (3)
- Restriction Enzyme Analysis of DNA Methylation in “Condensed” Chromatin of Ha-Ras-Transformed NIH 3T3 Cells (2000) (3)
- Resistance of murine LTA cells to oncogene--mediated progression from tumorigenic to metastatic phenotype. (1990) (2)
- Factor-2 Cross-Talk in Angiogenesis Osteopontin (Eta-1) and Fibroblast Growth (2003) (2)
- Cancer Metastasis: Tracking and Attacking a Moving Target (2015) (2)
- Improved Linear Contrast-Enhanced Ultrasound Imaging via Analysis of First-Order Speckle Statistics (2016) (2)
- A two-component speckle model for detection of microbubble signals in linear contrast-enhanced ultrasonography (2013) (2)
- Progression of Early Breast Cancer to an Invasive Phenotype (2013) (2)
- Tumor Dormancy in Liver Metastasis: Clinical and Experimental Evidence and Implications for Treatment (2011) (2)
- Osteopontin inhibits inducible nitric oxide synthase activity in rat vascular tissue. (1998) (2)
- Farnesylamine: an inhibitor of farnesylation and growth of ras-transformed cells. (1993) (2)
- Use of the Chick Embryo in Studying the Molecular Genetics of Metastasis (1986) (2)
- Oncogenes as Therapeutic Targets to Prevent Metastasis (2003) (2)
- The vascular-targeting agent, ZD6126, and the antiangiogenic agent, ZD6474, inhibit liver metastases via differential effects on metastatic vasculature. (2003) (2)
- Osteopontin (OPN): A novel tumor marker of potential utility in metastatic breast cancer. (2004) (1)
- Commentary Putative growth characteristics of micrometastatic breast cancer (2008) (1)
- In vivo evaluation of an objective method to select power Doppler wall filter cut-off frequency for microvascular quantification (2014) (1)
- Review Tumour dormancy in breast cancer: an update (2007) (1)
- Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial (2014) (1)
- A new breast cancer model for lymphatic metastasis. (2007) (1)
- WE‐D‐I‐609‐07: Analysis of Growth Dynamics of Treated Murine Liver Metastases Using Volumetric Ultrasound Micro‐Imaging (2005) (1)
- Factors in resistance to chemotherapy cure (1987) (1)
- Osteopontin: A Ras-Regulated Gene That Contributes to Tumor Metastasis (2002) (1)
- DNA Transfection, Genetic Instability, and Metastasis (1989) (1)
- Re: Medroxyprogesterone acetate and metastases: of mice and (wo)men. (2005) (1)
- Tumor metastasis, physical sciences and the value of multidisciplinary collaborations (2016) (1)
- Distinct karyotypes in three breast cancer cell lines --21PTCi, 21NTCi, and 21MT-1 --derived from the same patient and representing different stages of tumor progression. (2008) (1)
- Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization (2018) (0)
- 467 Stromal compartment influences on response to therapy (2004) (0)
- Interactions of Normal Tissues and Systems with Metastatic Cells: Impact on Location, Survival and Growth (2013) (0)
- Survive and Extravasate Fate of Melanoma Cells Entering the Microcirculation : Over 80 % Updated (2006) (0)
- THE CELL TO CELL INTERACTION OF BREAST CANCER CELLS REGULATES CANCER INVASION VIA ADAM15 (2012) (0)
- Development of Animal Models for Studying How Timing of Surgery During the Menstrual Cycle Can Affect Breast Cancer Metastasis and Survival (2002) (0)
- THE FUNCTIONAL ROLE OF OSTEOPONTIN (OPN) IN BREAST CANCER MALIGNANCY (2002) (0)
- Preface (1995) (0)
- PD33-01 THE VIABILITY, METABOLISM AND VASCULARIZATION OF RENAL CELL CARCINOMA CELL LINES AND XENOGRAFTS CAN BE TARGETED THROUGH INHIBITION OF ENDOGENOUS HYDROGEN SULFIDE PRODUCTION (2015) (0)
- IDENTIFYING THE SPATIO‐FUNCTIONAL ORIGINS OF DRUG RESISTANCE WITH RAPID TUMOR XENOGRAFTS: MP72‐14 (2018) (0)
- Abstract 3119: Predicting drug resistance in metastatic renal cell carcinoma: Personalized medicine by xenografting patient tumors into chicken embryos (2014) (0)
- Reduced variability of contrast-enhanced ultrasound perfusion estimates in a patient-derived xenograft model via analysis of speckle statistics (2017) (0)
- Editorial: Revisiting seed and soil: A new approach to target hibernating dormant tumor cells (2023) (0)
- 85. Pattern of expression of metastasis associated genes in breast cancer resected during various menstrual phases (1995) (0)
- PLASMA OSTEOPONTIN AS A MARKER FOR METASTATIC CANCER (2002) (0)
- Re-expression of osteopontin in Breast Cancer Metastasis Suppressor 1 expressing breast cancer cells restores metastatic potential (2006) (0)
- Brief Wild-Type p53 Renders Mouse Astrocytes Resistant to l,3-Bis(2-chloroethyl)-l-nitrosourea despite the Absence of a p53-dependent Cell Cycle Arrest1 (2006) (0)
- Genes and metastasis: experimental advances and clinical implications (2008) (0)
- Abstract 1687: A BRCA2-targeting antisense oligodeoxynucleotide enhances cisplatin effectiveness by decreasing human tumor cell proliferation, metastatic frequency, and metabolic response (2014) (0)
- Invasion and metastasis—recent advances and future challenges (2015) (0)
- 729: Osteopontin Levels in the Plasma of Patients with Transitional Cell Carcinoma of the Bladder may be Predictive of Recurrence and Survival (2004) (0)
- Abstract 4055: The transcriptional regulator TBX3 promotes progression of cells representing early premalignant breast cancer (2014) (0)
- Original Article Role of plasma osteopontin as a biomarker in locally advanced breast cancer (2015) (0)
- Introduction: Breast Cancer Progression and Metastasis: Experimental Studies and Clinical Translation (2001) (0)
- Metastasis: a current perspective (2008) (0)
- The authors' reply (2009) (0)
- Astrocytomas to Chemotherapy Differential Response of Oligodendrogliomas and Chemosensitivity in Glial Cell Lineages Correlate with Differential Expression of Drug Resistance Genes and Updated (2000) (0)
- DRUG RESISTANCE CONSEQUENCES OF TUMOR HETEROGENEITY IN METASTATIC RENAL CELL CARCINOMA USING ULTRA‐FAST PATIENT DERIVED XENOGRAFTS AND MULTIREGIONAL GENOMIC SEQUENCING: MP73‐06 (2017) (0)
- Preclinical Liver Metastases: Three-Dimensional High-Frequency Ultrasound Imaging (2009) (0)
- Prospective Evaluation of Radiation Pneumonitis in Neoadjuvant Concurrent Docetaxel and Radiation Therapy for Locally Advanced Breast Cancer (2012) (0)
- Brain metastases from breast cancer: lessons from experimental magnetic resonance imaging studies and clinical implications (2013) (0)
- A method to validate quantitative high-frequency power Doppler ultrasound with fluorescence in vivo video microscopy (2013) (0)
- Motility and Chemotaxis of Arginine-glycine-aspartic Acid , thereby Stimulating Cell Integrins to Permit Cells to Bind to Osteopontin Independently 1-containing β CD 44 Variants but not CD 44 s Cooperate with Updated (1998) (0)
- CJN volume 22 issue 2 Cover and Front matter (1995) (0)
- Abstract A09: PDXovo: Ultra-fast in vivo drug sensitivity matrices for renal cell carcinoma patients prior to administration of targeted therapy (2016) (0)
- Metastasis Research Society VII International Congress (Part II). 7-10 October 1998, San Diego, CA, USA. (1999) (0)
- Reduced variability of CEUS perfusion estimates in a patient-derived xenograft model via analysis of speckle statistics (2017) (0)
- 970 Understanding the Heterogeneity of Brain Metastases from Breast Cancer : Lessons from New Models and Experimental Magnetic Resonance Imaging (2013) (0)
- Image analysis of feulgen-stained -transformed NIH 3T3 cell clones (1990) (0)
- P2-12-28: Studies of a Malignancy-Associated Protein, Osteopontin, in NCIC CTG MA.14, a Randomized Trial of Tamoxifen Versus Combined Tamoxifen and Octreotide LAR in Adjuvant Treatment of Women with Early Breast Cancer. (2011) (0)
- The Use of Cellular MRI and Magnetic Particles to Study Cancer Stem Cells (2009) (0)
- Cyclin A2, a novel regulator of EMT (2014) (0)
- Osteopontin , Fibronectin , and Laminin-transformed NIH 3 T 3 Cells to ras Adhesion of Metastatic , Updated Version (2006) (0)
- Dormancy and Metastasis of Melanoma Cells to Lymph Nodes, Lung and Liver (2013) (0)
- Cancer Metastasis: Metastatic Inefficiency and Tumor Dormancy (2011) (0)
- Abstract 5099: Abrogation of cancer cell extravasation in renal cell carcinoma PDX lines via invadopodia dysregulation mediated by PAK1 inhibitors (2015) (0)
- Comment on: Medroxyprogesterone acetate and metastases : Of mice and (Wo)men. Author's reply (2005) (0)
- Introduction to special issue on ‘epigenetic and physiological regulation of metastasis’ (2008) (0)
- Ovarian Cancer Biomarkers in Urine 55 Commentary onYe et al . , p . 432 (2005) (0)
- P3-16-11: Prospective Evaluation of Radiation Pneumonitis in Neoadjuvant Concurrent Docetaxel and Radiation Therapy for Locally Advanced Breast Cancer. (2011) (0)
- Abstract 4716: Discovery of biomarkers from highly enriched prostate cancer microparticles for prognostication of prostate cancer (2014) (0)
- EXPRESSION PROFILING IDENTIFIES OSTEOPONTIN AS LEADING CANDIDATE TUMOR PROGRESSION MARKER USING POOLED HUMAN COLON CANCER SPECIMENS (2002) (0)
- Effects of ras Oncogenes on Metastatic Capacity (1992) (0)
- Ovarian cancer biomarkers in urine. Commentary (2006) (0)
- Compound speckle model demonstrates two-phase wash-in of contrast-enhanced ultrasound cine loops (2018) (0)
- Abstract 4329: In vivo visualization of epithelial-mesenchymal transition in real time using a rapidly tuneable E-cadherin (2010) (0)
- The thrombin cleavage domain of osteopontin is important for mediating growth and adhesive properties of human breast cancer cells (2006) (0)
- P34 Endogenous hydrogen sulfide production plays a role in the survival, growth and neovascularization of renal cell carcinoma tumours (2014) (0)
- 199 Novel Functions of Cyclin A2 in Epithelial-Mesenchymal Transition and Metastasis (2012) (0)
- Primary melanoma tumor inhibits metastasis through alterations in systemic hemostasis (2016) (0)
- Abstract 968: Invadopodia formation and microparticle release are required for cancer cell extravasation in vivo (2011) (0)
- In vivo Tracking of Growth and Dormancy of Solitary Cells in a Mouse Model of Breast Cancer Metastasis to Brain using MRI (2005) (0)
- Tumor metastasis: Historical perspective and future prospects (1992) (0)
- Non-invasive visualization of differential BBB permeability and in vivo quantification of tumor volume in an experimental model of breast cancer metastasis to the brain , using Gadolinium-enhanced MRI and 3 D bSSFP (2010) (0)
- The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer (2016) (0)
- 187 Predicting targeted therapy tumor resistance in renal cell carcinoma patient-derived xenografts implanted into chicken embryos (2014) (0)
- Abstract P1-14-13: Increased Pathologic Complete Response Rate and Reduced Tumour RNA Levels Upon Treatment of Locally Advanced Breast Cancer with Neoadjuvant Concurrent Chemotherapy and Radiation (2012) (0)
- Complexity and Dynamic Heterogeneity of the Process of Cancer Metastasis (2010) (0)
- Half brain irradiation in a murine model of breast cancer brain metastasis: magnetic resonance imaging and histological assessments of dose-response (2018) (0)
- Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts (2014) (0)
- Osteopontin (OPN): A novel tumor marker of potential utility in metastatic breast cancer (2004) (0)
- Preclinical Cell and Tumor Models for Evaluating Radiopharmaceuticals in Oncology (2010) (0)
- Abstract 3432: A genome-wide shRNA screen for suppressors of prostate cancer cell invasion (2014) (0)
- Abstract B02: Ultrasound evaluation of anti-angiogenic therapy on patient-derived renal cell carcinoma xenograft tumors in the chicken embryo model (2015) (0)
- Abstract 4000: Cellular MRI of human breast cancer cells labeled with gadofluorine M (2010) (0)
- Is Ki67 a prognostic factor for survival inlow-grade glioma? (2000) (0)
- Abstract 3193: Expression analysis reveals candidate genes involved in highly invasive high-hyaluronan binding subpopulations of prostate cancer cell lines (2015) (0)
- MP35-15 DEVELOPING A PATIENT-DERIVED XENOGRAFT MODEL USING CHICKEN EMBRYOS TO PREDICT TARGETED THERAPY TUMOR RESISTANCE IN RENAL CELL CARCINOMAS (2014) (0)
- Advances in Brief Estrous Cycle Influences Organ-specific Metastasis of B 16 F 10 Melanoma Cells 1 (2003) (0)
- Circulating Tumor Cells and Tumor Dormancy (2016) (0)
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What Schools Are Affiliated With Ann F. Chambers?
Ann F. Chambers is affiliated with the following schools:
