Anne Moscona
#145,887
Most Influential Person Now
American pediatrician and virologist
Anne Moscona's AcademicInfluence.com Rankings
Anne Mosconamedical Degrees
Medical
#2987
World Rank
#3436
Historical Rank
#486
USA Rank
Pediatrics
#76
World Rank
#89
Historical Rank
#19
USA Rank
Anne Mosconabiology Degrees
Biology
#10973
World Rank
#14339
Historical Rank
#2535
USA Rank
Virology
#283
World Rank
#290
Historical Rank
#53
USA Rank
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Medical Biology
Anne Moscona's Degrees
- Doctorate Medicine Columbia University
- PhD Microbiology Columbia University
Why Is Anne Moscona Influential?
(Suggest an Edit or Addition)According to Wikipedia, Anne Moscona is an American virologist and pediatrician. She is best known for identifying cell entry mechanisms for enveloped respiratory viruses, elucidating general infection mechanisms that apply to parainfluenza virus, Nipah virus, measles virus, and other viruses, and for applying this knowledge to identify antiviral strategies to prevent infection by viruses including SARS-CoV-2. She is frequently consulted as a medical expert during viral outbreaks, including epidemic and pandemic influenza. Since 2016, she has served as the Sherie L. Morrison Professor Microbiology & Immunology, Professor of Pediatrics, and Professor of Physiology & Cellular Biophysics at Columbia University Medical Center in New York City, where she directs the Center for Host Pathogen Interaction. In 2022, Moscona was elected as president of the American Society for Virology, the nation's leading virology research organization, and will lead the organization starting in July 2023. For the last two years she has served the American Society for Virology as Councilor for Medical Virology.
Anne Moscona's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Role of cell shape in growth control (1978) (2405)
- Neuraminidase inhibitors for influenza. (2005) (1056)
- Global transmission of oseltamivir-resistant influenza. (2009) (465)
- A three-dimensional model of human lung development and disease from pluripotent stem cells (2017) (373)
- Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum (2020) (354)
- Oseltamivir resistance--disabling our influenza defenses. (2005) (326)
- Measurement of the mutation rates of animal viruses: influenza A virus and poliovirus type 1 (1986) (277)
- The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. (2001) (238)
- A broad-spectrum antiviral targeting entry of enveloped viruses (2010) (223)
- In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age (2020) (176)
- Medical management of influenza infection. (2008) (133)
- Entry of parainfluenza virus into cells as a target for interrupting childhood respiratory disease. (2005) (118)
- Immunization of pediatric solid organ transplant candidates and recipients. (2000) (111)
- Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry (2010) (108)
- Fusion properties of cells persistently infected with human parainfluenza virus type 3: participation of hemagglutinin-neuraminidase in membrane fusion (1991) (101)
- Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets (2020) (100)
- Triggering of Human Parainfluenza Virus 3 Fusion Protein (F) by the Hemagglutinin-Neuraminidase (HN) Protein: an HN Mutation Diminishes the Rate of F Activation and Fusion (2003) (90)
- Authentic Modeling of Human Respiratory Virus Infection in Human Pluripotent Stem Cell-Derived Lung Organoids (2019) (89)
- Viral Entry Inhibitors Targeted to the Membrane Site of Action (2010) (88)
- A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the FusionMechanism (2007) (87)
- Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets (2021) (78)
- Simulating Henipavirus Multicycle Replication in a Screening Assay Leads to Identification of a Promising Candidate for Therapy (2009) (77)
- Effect of Temperature on Adhesion to Glass and Histogenetic Cohesion of Dissociated Cells (1961) (75)
- Relative affinity of the human parainfluenza virus type 3 hemagglutinin-neuraminidase for sialic acid correlates with virus-induced fusion activity (1993) (75)
- Capturing a Fusion Intermediate of Influenza Hemagglutinin with a Cholesterol-conjugated Peptide, a New Antiviral Strategy for Influenza Virus* (2011) (73)
- A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. (2010) (73)
- The Anti-Influenza Virus Agent 4-GU-DANA (Zanamivir) Inhibits Cell Fusion Mediated by Human Parainfluenza Virus and Influenza Virus HA (2000) (72)
- A General Strategy to Endow Natural Fusion-protein-Derived Peptides with Potent Antiviral Activity (2012) (66)
- Human Parainfluenza Virus Infection of the Airway Epithelium: Viral Hemagglutinin-Neuraminidase Regulates Fusion Protein Activation and Modulates Infectivity (2009) (65)
- Molecular Determinants of Antiviral Potency of Paramyxovirus Entry Inhibitors (2007) (64)
- Inhibition of Hendra Virus Fusion (2006) (64)
- Paramyxovirus Receptor-Binding Molecules: Engagement of One Site on the Hemagglutinin-Neuraminidase Protein Modulates Activity at the Second Site (2006) (63)
- Influence of the Human Parainfluenza Virus 3 Attachment Protein's Neuraminidase Activity on Its Capacity To Activate the Fusion Protein (2005) (62)
- Mechanism of Fusion Triggering by Human Parainfluenza Virus Type III (2011) (61)
- Hemagglutinin-neuraminidase of human parainfluenza 3: role of the neuraminidase in the viral life cycle. (1995) (61)
- Fatal Measles Virus Infection Prevented by Brain-Penetrant Fusion Inhibitors (2013) (58)
- Inhibition of Parainfluenza Virus Type 3 and Newcastle Disease Virus Hemagglutinin-Neuraminidase Receptor Binding: Effect of Receptor Avidity and Steric Hindrance at the Inhibitor Binding Sites (2004) (56)
- Fusion properties of cells infected with human parainfluenza virus type 3: receptor requirements for viral spread and virus-mediated membrane fusion (1992) (56)
- Antibody responses to SARS-CoV2 are distinct in children with MIS-C compared to adults with COVID-19 (2020) (54)
- The Second Receptor Binding Site of the Globular Head of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Activates the Stalk of Multiple Paramyxovirus Receptor Binding Proteins To Trigger Fusion (2012) (54)
- The Role of Quantitative Epstein-Barr Virus Polymerase Chain Reaction and Preemptive Immunosuppression Reduction in Pediatric Liver Transplantation: A Preliminary Experience (2001) (53)
- Spring-Loaded Model Revisited: Paramyxovirus Fusion Requires Engagement of a Receptor Binding Protein beyond Initial Triggering of the Fusion Protein (2011) (52)
- Human Parainfluenza Virus Type 3 HN-Receptor Interaction: Effect of 4-Guanidino-Neu5Ac2en on a Neuraminidase-Deficient Variant (2001) (51)
- Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain (2020) (47)
- Prevention of Measles Virus Infection by Intranasal Delivery of Fusion Inhibitor Peptides (2014) (46)
- Prospective longitudinal analysis of quantitative Epstein-Barr virus polymerase chain reaction in pediatric liver transplant recipients. (1999) (45)
- Mutations in Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Causing Increased Receptor Binding Activity and Resistance to the Transition State Sialic Acid Analog 4-GU-DANA (Zanamivir) (2003) (44)
- Interaction between the Hemagglutinin-Neuraminidase and Fusion Glycoproteins of Human Parainfluenza Virus Type III Regulates Viral Growth In Vivo (2013) (39)
- Fusion Promotion by a Paramyxovirus Hemagglutinin-Neuraminidase Protein: pH Modulation of Receptor Avidity of Binding Sites I and II (2007) (39)
- Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro (2009) (38)
- Development and validation of a chemiluminescent immunodetection assay amenable to high throughput screening of antiviral drugs for Nipah and Hendra virus. (2008) (38)
- Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides (2017) (37)
- Measles Fusion Machinery Is Dysregulated in Neuropathogenic Variants (2015) (37)
- Mechanism of Interference Mediated by Human Parainfluenza Virus Type 3 Infection (2000) (36)
- In Vivo Efficacy of Measles Virus Fusion Protein-Derived Peptides Is Modulated by the Properties of Self-Assembly and Membrane Residence (2016) (35)
- Premature Activation of the Paramyxovirus Fusion Protein before Target Cell Attachment with Corruption of the Viral Fusion Machinery* (2011) (34)
- Virus-receptor interactions of human parainfluenza viruses types 1, 2 and 3. (1999) (34)
- The use of a quantitative fusion assay to evaluate HN-receptor interaction for human parainfluenza virus type 3. (1999) (34)
- Study of the impact of oseltamivir on the risk for pneumonia and other outcomes of influenza, 2000-2005. (2008) (33)
- Adaptation of Human Parainfluenza Virus to Airway Epithelium Reveals Fusion Properties Required for Growth in Host Tissue (2012) (32)
- Regulation of Paramyxovirus Fusion Activation: the Hemagglutinin-Neuraminidase Protein Stabilizes the Fusion Protein in a Pretriggered State (2012) (32)
- Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance (2017) (31)
- In vivo antiviral host response to SARS-CoV-2 by viral load, sex, and age (2020) (30)
- Fusion Inhibitory Lipopeptides Engineered for Prophylaxis of Nipah Virus in Primates (2018) (30)
- Kinetic Dependence of Paramyxovirus Entry Inhibition (2009) (28)
- Viral Entry Properties Required for Fitness in Humans Are Lost through Rapid Genomic Change during Viral Isolation (2018) (26)
- The Cell Biology of Acute Childhood Respiratory Disease: Therapeutic Implications (2006) (25)
- Characterization of human parainfluenza virus type 3 persistent infection in cell culture (1990) (25)
- Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection (2020) (24)
- A Single Amino Acid Alteration in the Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Glycoprotein Confers Resistance to the Inhibitory Effects of Zanamivir on Receptor Binding and Neuraminidase Activity (2001) (24)
- Electron Tomography Imaging of Surface Glycoproteins on Human Parainfluenza Virus 3: Association of Receptor Binding and Fusion Proteins before Receptor Engagement (2015) (23)
- Synthetic Protocells Interact with Viral Nanomachinery and Inactivate Pathogenic Human Virus (2011) (23)
- Contribution of the Human Parainfluenza Virus Type 3 HN-Receptor Interaction to Pathogenesis In Vivo (2001) (22)
- Analysis of a Subacute Sclerosing Panencephalitis Genotype B3 Virus from the 2009-2010 South African Measles Epidemic Shows That Hyperfusogenic F Proteins Contribute to Measles Virus Infection in the Brain (2018) (22)
- Measles Virus Fusion Machinery Activated by Sialic Acid Binding Globular Domain (2013) (22)
- Defective interfering particles of human parainfluenza virus type 3 are associated with persistent infection in cell culture. (1991) (21)
- Measles Virus Bearing Measles Inclusion Body Encephalitis-Derived Fusion Protein Is Pathogenic after Infection via the Respiratory Route (2019) (21)
- Unity in diversity: shared mechanism of entry among paramyxoviruses. (2015) (21)
- Circulating Clinical Strains of Human Parainfluenza Virus Reveal Viral Entry Requirements for In Vivo Infection (2014) (21)
- Rapid Screening for Entry Inhibitors of Highly Pathogenic Viruses under Low-Level Biocontainment (2012) (20)
- Identification of a Region in the Stalk Domain of the Nipah Virus Receptor Binding Protein That Is Critical for Fusion Activation (2013) (20)
- Analysis of human parainfluenza virus 3 receptor binding variants: evidence for the use of a specific sialic acid-containing receptor. (1996) (20)
- Effective in Vivo Targeting of Influenza Virus through a Cell-Penetrating/Fusion Inhibitor Tandem Peptide Anchored to the Plasma Membrane. (2018) (20)
- Features of Circulating Parainfluenza Virus Required for Growth in Human Airway (2016) (17)
- News about influenza B drug resistance that cannot be ignored. (2007) (15)
- Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent. (2019) (14)
- Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain (2021) (14)
- Interaction of human parainfluenza virus type 3 with the host cell surface. (1997) (13)
- The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell–derived lung progenitors in 3D (2021) (13)
- Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length (2017) (12)
- Hijacking the Fusion Complex of Human Parainfluenza Virus as an Antiviral Strategy (2020) (12)
- Structure-Stability-Function Mechanistic Links in the Anti-Measles Virus Action of Tocopherol-Derivatized Peptide Nanoparticles. (2018) (11)
- Management of respiratory syncytial virus infections in the immunocompromised child. (2000) (10)
- Persistent infection with human parainfluenza virus 3 in CV-1 cells: analysis of the role of defective interfering particles. (1993) (9)
- Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor. (2019) (9)
- Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum (2020) (9)
- A daring treatment and a successful outcome: The need for targeted therapies for pediatric respiratory viruses (2007) (7)
- Inhibiting Human Parainfluenza Virus Infection by Preactivating the Cell Entry Mechanism (2019) (7)
- Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection (2021) (7)
- Human parainfluenza virus fusion complex glycoproteins imaged in action on authentic viral surfaces (2020) (7)
- Intermediates in SARS-CoV-2 spike–mediated cell entry (2022) (6)
- Bronchiolitis: too-familiar yet too-mysterious disease of childhood. (2012) (6)
- Properties of human parainfluenza virus type 3 RNA polymerase/replicase activity in vitro: consensus with other negative-stranded RNA viruses (1991) (6)
- Inhibition of Measles Viral Fusion Is Enhanced by Targeting Multiple Domains of the Fusion Protein. (2021) (5)
- Paramyxoviruses: Parainfluenza Viruses (2014) (5)
- M-Protein Peptides of Influenza Virus: Application as Antiviral Agents, (1992) (4)
- Virology under the Microscope—a Call for Rational Discourse (2023) (4)
- Potency of Fusion-Inhibitory Lipopeptides against SARS-CoV-2 Variants of Concern (2022) (3)
- RSV vaccine: Beating the virus at its own game (2015) (3)
- Single-chain variable fragment antibody constructs neutralize measles virus infection in vitro and in vivo (2021) (3)
- Effects of single α-to-β residue replacements on recognition of an extended segment in a viral fusion protein. (2020) (3)
- Self-assembly Stability Compromises the Efficacy of Tryptophan-Containing Designed Anti-measles Virus Peptides (2019) (3)
- Modeling Infection and Tropism of Human Parainfluenza Virus Type 3 in Ferrets (2022) (2)
- Human parainfluenza virus evolution during lung infection of immunocompromised individuals promotes viral persistence (2021) (2)
- Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model (2021) (2)
- Rapid and Flexible Platform To Assess Anti-SARS-CoV-2 Antibody Neutralization and Spike Protein-Specific Antivirals (2021) (2)
- Faculty Opinions recommendation of Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease. (2014) (2)
- Measles fusion complexes from central nervous system clinical isolates: decreased interaction between hemagglutinin and fusion proteins (2021) (2)
- CSI Microbiology: Emerging Pathogens and a Staged Strategy for Detection and Discovery (2007) (2)
- Faculty Opinions recommendation of Human metapneumovirus (HMPV) binding and infection are mediated by interactions between the HMPV fusion protein and heparan sulfate. (2012) (1)
- Virology under the Microscope—a Call for Rational Discourse (2023) (1)
- Repurposing an In Vitro Measles Virus Dissemination Assay for Screening of Antiviral Compounds (2022) (1)
- Human parainfluenza virus evolution during lung infection of immunocompromised humans promotes viral persistence. (2021) (1)
- Parainfluenza virus entry at the onset of infection. (2021) (1)
- Endocarditis due to Haemophilus aphrophilus (1984) (1)
- Virology under the Microscope—a Call for Rational Discourse (2023) (1)
- Erratum for Gui et al., Electron Tomography Imaging of Surface Glycoproteins on Human Parainfluenza Virus 3: Association of Receptor Binding and Fusion Proteins before Receptor Engagement (2016) (0)
- Faculty Opinions recommendation of Soluble respiratory syncytial virus fusion protein in the fully cleaved, pretriggered state is triggered by exposure to low-molarity buffer. (2011) (0)
- COMPARISON OF THE VIRUS-RECEPTOR INTERACTIONS OF HUMAN PARAINFLUENZA VIRUSES TYPES 1, 2 and 3. † 995 (1996) (0)
- Measurement oftheMutation RatesofAnimalViruses: Influenza A VirusandPoliovirus Type1 (1986) (0)
- identification of a promising candidate for therapy. (2009) (0)
- Faculty Opinions recommendation of Molecular determinants of proteolytic disassembly of the reovirus outer capsid. (2012) (0)
- Role of the Human Parainfluenza Virus Type 3 Fusion Machinery in Viral Growth in the Natural Host (2016) (0)
- Faculty Opinions recommendation of Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine. (2012) (0)
- Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms (2023) (0)
- Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection (2022) (0)
- A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the Fusion Mechanism (cid:1) (2007) (0)
- Chikungunya infection: de-linking replication from symptomatology reveals the central role of muscle. (2020) (0)
- STRUCTURAL REARRANGEMENTS IN THE PARAMYXOVIRUS FUSION COMPLEX IN THE PRESENCE OF A NOVEL ANTIVIRAL. (2016) (0)
- Faculty Opinions recommendation of Architecture of respiratory syncytial virus revealed by electron cryotomography. (2013) (0)
- Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection (2022) (0)
- Faculty Opinions recommendation of Bats host major mammalian paramyxoviruses. (2012) (0)
- (Zanamivir)Sialic Acid Analog 4-GU-DANA Activity and Resistance to the Transition Causing Increased Receptor Binding Type 3 Hemagglutinin-Neuraminidase Mutations in Human Parainfluenza Virus (2013) (0)
- Fusion Properties ofCells Infected withHumanParainfluenza Virus Type3:Receptor Requirements forViral Spread andVirus-Mediated MembraneFusion (1992) (0)
- SARS-CoV-2 infection and recovery in children: Distinct T cell responses in MIS-C compared to COVID-19. (2023) (0)
- Understanding the transmission of tuberculosis (TB) to children using insertion sequence (IS)-6110 based southern blot hybridization (SBH) and restriction fragment length polymorphism analysis (RFLP). • 434 (1997) (0)
- Respiroviruses: Parainfluenza Virus (2010) (0)
- DT388-C-Peptide: Novel Recombinant Antiviral for Prevention and Early Treatment of SARS-Cov-2 Infection (2021) (0)
- Development of airways protection against respiratory nipah virus infection by inhalation of antiviral peptides (2021) (0)
- Human Parainfluenza Virus Infection of the Airway Epithelium: Viral Hemagglutinin-Neuraminidase Regulates Fusion Protein Activation and Modulates Infectivity (cid:1) (2009) (0)
- Faculty Opinions recommendation of siRNA screen for genes that affect Junín virus entry uncovers voltage-gated calcium channels as a therapeutic target. (2014) (0)
- Faculty Opinions recommendation of In vivo analysis of infectivity, fusogenicity, and incorporation of a mutagenic viral glycoprotein library reveals determinants for virus incorporation. (2016) (0)
- Faculty Opinions recommendation of DC-SIGN as a receptor for phleboviruses. (2011) (0)
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Anne Moscona is affiliated with the following schools:
