Anne O'Garra | Academic Influence

Anne O'Garra's AcademicInfluence.com Rankings

Anne O'Garra

Biology

#1693

World Rank

#2759

Historical Rank

Immunology

#115

World Rank

#122

Historical Rank

biology Degrees

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Biology

Anne O'Garra's Degrees

PhD Immunology University of Oxford

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According to Wikipedia, Anne O'Garra FRS FMedSci is a British immunologist who has made important discoveries on the mechanism of action of Interleukin 10. O'Garra was born in Gibraltar. Biography She was born to Fred O,Garra and Isaac Wimett in 1954, as a child she was noted as having a keen mind.

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Anne O'Garra's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Interleukin-10 and the interleukin-10 receptor. (2001) (6573)
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis (1997) (4062)
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. (1993) (3465)
IL-10 inhibits cytokine production by activated macrophages. (1991) (3059)
The regulation of IL-10 production by immune cells (2010) (2510)
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. (1991) (1983)
Cytokines induce the development of functionally heterogeneous T helper cell subsets. (1998) (1744)
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. (1995) (1714)
Type I interferons in infectious disease (2015) (1584)
An Interferon-Inducible Neutrophil-Driven Blood Transcriptional Signature in Human Tuberculosis (2010) (1449)
In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines (2002) (1250)
Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology (2001) (1158)
The immune response in tuberculosis. (2013) (1062)
1α,25-Dihydroxyvitamin D3 Has a Direct Effect on Naive CD4+ T Cells to Enhance the Development of Th2 Cells1 (2001) (893)
Regulatory T cells and mechanisms of immune system control (2004) (874)
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model (1995) (812)
IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB (1997) (756)
Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. (1992) (745)
IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells 1 (2004) (723)
Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma (2005) (713)
Flexibility of Mouse Classical and Plasmacytoid-derived Dendritic Cells in Directing T Helper Type 1 and 2 Cell Development (2003) (649)
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations (1995) (629)
Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. (2005) (613)
TH1 cells control themselves by producing interleukin-10 (2007) (612)
The Development of Murine Plasmacytoid Dendritic Cell Precursors Is Differentially Regulated by FLT3-ligand and Granulocyte/Macrophage Colony-Stimulating Factor (2002) (592)
Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells (2005) (580)
Ly‐1 B (B‐1) cells are the main source of B cell‐derived interleukin 10 (1992) (550)
IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. (2004) (546)
T cell genetic background determines default T helper phenotype development in vitro (1995) (510)
Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells (2009) (504)
Biological properties of interleukin 10. (1992) (494)
Reversibility of T helper 1 and 2 populations is lost after long-term stimulation (1996) (484)
The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. (1998) (455)
The molecular basis of T helper 1 and T helper 2 cell differentiation. (2000) (455)
Role of cytokines in determining T-lymphocyte function. (1994) (453)
Gata-3 Induces T Helper Cell Type 2 (Th2) Cytokine Expression and Chromatin Remodeling in Committed Th1 Cells (2000) (444)
IL‐10 Family Cytokines IL‐10 and IL‐22: from Basic Science to Clinical Translation (2019) (438)
The role of IL-10 in immune regulation during M. tuberculosis infection (2011) (420)
Strategies for use of IL‐10 or its antagonists in human disease (2008) (419)
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation (1994) (410)
Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein (1996) (398)
SOCS-3 regulates onset and maintenance of TH2-mediated allergic responses (2003) (379)
Diversity of Cytokine Synthesis and Function of Mouse CD4+ T Cells (1991) (376)
Reversal of Tumor-induced Dendritic Cell Paralysis by CpG Immunostimulatory Oligonucleotide and Anti–Interleukin 10 Receptor Antibody (2002) (376)
Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10. (1990) (363)
Type I interferon dependence of plasmacytoid dendritic cell activation and migration (2005) (357)
Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells. (1999) (357)
From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines (2012) (354)
Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependent (1993) (336)
Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development. (1996) (334)
Interleukin-10 Production by Th1 Cells Requires Interleukin-12-Induced STAT4 Transcription Factor and ERK MAP Kinase Activation by High Antigen Dose (2009) (323)
Macrophages and Myeloid Dendritic Cells, but Not Plasmacytoid Dendritic Cells, Produce IL-10 in Response to MyD88- and TRIF-Dependent TLR Signals, and TLR-Independent Signals1 (2006) (321)
Interleukins and the immune system 1. (1989) (306)
Neutrophils in tuberculosis: friend or foe? (2012) (290)
Differential effect of IL-10 on dendritic cell-induced T cell proliferation and IFN-gamma production. (1993) (273)
CD4+ T-cell subsets in autoimmunity. (1997) (270)
IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. (1997) (265)
CD8+ T cells control Th2‐driven pathology during pulmonary respiratory syncytial virus infection (1997) (259)
The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. (1988) (252)
Biology and therapeutic potential of interleukin-10 (2019) (245)
Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers (2013) (239)
Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice (2001) (237)
A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure. (2002) (228)
Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung (2010) (225)
CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production. (2005) (223)
Tripartite-motif proteins and innate immune regulation. (2011) (222)
Further checkpoints in Th1 development. (2002) (221)
'B-cell factors' are pleiotropic. (1988) (214)
GATA-3 significantly downregulates IFN-gamma production from developing Th1 cells in addition to inducing IL-4 and IL-5 levels. (1999) (202)
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers (2020) (202)
Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy (2012) (195)
IL-27 Promotes IL-10 Production by Effector Th1 CD4+ T Cells: A Critical Mechanism for Protection from Severe Immunopathology during Malaria Infection (2012) (193)
TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells (2009) (184)
Eosinophil differentiation factor also has B-cell growth factor activity: proposed name interleukin 4. (1986) (178)
TGF‐β1 down‐regulates Th2 development and results in decreased IL‐4‐induced STAT6 activation and GATA‐3 expression (2000) (173)
Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells (2006) (172)
From IL-10 to IL-12: how pathogens and their products stimulate APCs to induce TH1 development (2009) (169)
Cutting Edge: Chromatin Remodeling at the IL-4/IL-13 Intergenic Regulatory Region for Th2-Specific Cytokine Gene Cluster1 (2000) (167)
The role of 1α,25‐dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+and IL‐10+ CD4+ T cells (2012) (167)
Th1 and Th2 cytokine induction in pulmonary T cells during infection with respiratory syncytial virus. (1996) (166)
Type I interferon‐dependent and ‐independent expression of tripartite motif proteins in immune cells (2008) (164)
GATA-3 Directly Remodels the IL-10 Locus Independently of IL-4 in CD4+ T Cells (2006) (164)
IL-1α and TNF-α Are Required for IL-12-Induced Development of Th1 Cells Producing High Levels of IFN-γ in BALB/c But Not C57BL/6 Mice (1998) (160)
Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4+ T cells (2012) (158)
The regulation of IL-10 expression. (2014) (153)
Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography (2016) (152)
Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing in Mycobacterium tuberculosis–Infected Macrophages (2014) (150)
Blockade of IL-10 Signaling during Bacillus Calmette-Guérin Vaccination Enhances and Sustains Th1, Th17, and Innate Lymphoid IFN-γ and IL-17 Responses and Increases Protection to Mycobacterium tuberculosis Infection (2012) (150)
Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells. (1999) (148)
Type I interferons in tuberculosis: Foe and occasionally friend (2018) (145)
T-cell subsets in autoimmunity. (1993) (144)
The human immune response to tuberculosis and its treatment: a view from the blood (2015) (143)
A Critical Role for Interleukin 18 in Primary and Memory Effector Responses to Listeria monocytogenes That Extends Beyond Its Effects on Interferon γ Production (2001) (142)
Identification of a Macrophage-Specific Chromatin Signature in the IL-10 Locus1 (2005) (140)
Pathogen-induced Th1 phenotype development in CD4+ αβ-TCR transgenic T cells is macrophage dependent (1993) (135)
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. (2006) (123)
IL-10 Regulates Viral Lung Immunopathology during Acute Respiratory Syncytial Virus Infection in Mice (2012) (122)
A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection (2017) (122)
Interleukin‐10 Suppresses the Development of Collagen Type II‐Induced Arthritis and Ameliorates Sustained Arthritis in Rats (1996) (120)
Influenza A Virus Impairs Control of Mycobacterium tuberculosis Coinfection Through a Type I Interferon Receptor–Dependent Pathway (2013) (118)
Cytokine Networking in Lungs of Immunocompetent Mice in Response to Inhaled Aspergillus fumigatus (2001) (117)
Characterization of cis-regulatory elements and nuclear factors conferring Th2-specific expression of the IL-5 gene: a role for a GATA-binding protein. (1998) (110)
Depletion of eosinophils in mice through the use of antibodies specific for C‐C chemokine receptor 3 (CCR3) (1999) (107)
Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis (2011) (103)
Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections (2020) (102)
Integrated T‐cell receptor and costimulatory signals determine TGF‐β‐dependent differentiation and maintenance of Foxp3+ regulatory T cells (2011) (100)
Highlights of 10 years of immunology in Nature Reviews Immunology (2011) (99)
Xid-associated resistance to experimental Chagas' disease is IFN-gamma dependent. (1993) (99)
T-cell subsets: Chemokine receptors guide the way (1998) (97)
Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice. (1993) (94)
Activation and proliferation signals in mouse B cells VIII. Induction of DNA synthesis in B cells by a combination of calcium ionophores and phorbol myristate acetate (1986) (94)
c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells (2018) (93)
Receptor Signalling and Crosstalk in B Lymphocytes (1987) (93)
Systems Biology Approaches Reveal a Specific Interferon-Inducible Signature in HTLV-1 Associated Myelopathy (2012) (91)
Local cytokine production in a murine model of Escherichia coli pyelonephritis. (1992) (89)
Role of cytokines in development of Th1 and Th2 cells. (1996) (88)
Development and function of T helper 1 cells. (2004) (88)
TPL-2–ERK1/2 Signaling Promotes Host Resistance against Intracellular Bacterial Infection by Negative Regulation of Type I IFN Production (2013) (88)
Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza (2018) (86)
IL‐10 Production by CD5 B Cells (1992) (85)
Identification of a novel thymocyte growth-promoting factor derived from B cell lymphomas. (1990) (84)
Twenty-first century Foxp3 (2003) (83)
T Cell–Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection (2017) (81)
Differentiation of human TH-17 cells does require TGF-β! (2008) (80)
IL-18 Receptors, Their Role in Ligand Binding and Function: Anti-IL-1RAcPL Antibody, a Potent Antagonist of IL-181 (2000) (80)
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses (2006) (80)
INTERLEUKINS AND THE IMMUNE SYSTEM 2 (1989) (79)
HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling (2015) (78)
Vaccination against tuberculosis: how can we better BCG? (2013) (76)
Mouse γδ TCR+NK1.1+ thymocytes specifically produce interleukin‐4, are major histocompatibility complex class I independent, and are developmentally related to αβ TCR+NK1.1+ thymocytes (1996) (74)
Early expression of cytokines in lymph nodes after treatment in vivo with Staphylococcus enterotoxin B. (1994) (73)
Type I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling (2016) (73)
Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis (2018) (72)
Anti–Interleukin 10 Receptor Monoclonal Antibody Is an Adjuvant for T Helper Cell Type 1 Responses to Soluble Antigen Only in the Presence of Lipopolysaccharide (2000) (71)
The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis (2014) (69)
Biological properties of interleukin 10 (1992) (68)
Differential representations of memory T cell subsets are characteristic of polarized immunity in leprosy and atopic diseases. (1999) (67)
Friend of GATA Is Expressed in Naive Th Cells and Functions As a Repressor of GATA-3-Mediated Th2 Cell Development1 (2002) (66)
Inflammasome Activation Underlying Central Nervous System Deterioration in HIV-Associated Tuberculosis (2016) (65)
The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis (2018) (65)
Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from alpha beta TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-gamma production is IFN-gamma-dependent. (1993) (64)
The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis (2016) (63)
Polymerase chain reaction for detection of cytokine gene expression. (1992) (63)
Sustained activation of the raf-MEK-ERK pathway elicits cytokine unresponsiveness in T cells. (1999) (63)
In vitro generation of IL-10-producing regulatory CD4+ T cells is induced by immunosuppressive drugs and inhibited by Th1- and Th2-inducing cytokines. (2003) (62)
Quantitative events determine the differentiation and function of helper T cells (2011) (62)
B Cells Producing Type I IFN Modulate Macrophage Polarization in Tuberculosis (2017) (61)
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis (2020) (61)
Immunomodulatory Role of Endogenous Interleukin-18 in Gamma Interferon-Mediated Resolution of Replicative Legionella pneumophila Lung Infection (2000) (60)
Identification of IL-6 as a T cell-derived factor that enhances the proliferative response of thymocytes to IL-4 and phorbol myristate acetate. (1988) (57)
The stability and reversibility of Th1 and Th2 populations. (1999) (57)
IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice. (1998) (57)
Cutting Edge: Ectopic Expression of the IL-12 Receptor-β2 in Developing and Committed Th2 Cells Does Not Affect the Production of IL-4 or Induce the Production of IFN-γ1 (2000) (56)
The role of macrophage- and dendritic cell-derived IL12 in Th1 phenotype development. (1995) (56)
Pillars article: development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. 1993. Science 260(5107): 547-549. (2008) (55)
25-Dihydroxyvitamin D 3 Has a Direct Effect on Naive CD 4 T Cells to Enhance the Development of Th 2 Cells 1 (2001) (50)
Cytokines and Ly-1 (B1) B cells. (1992) (49)
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis (2020) (49)
Interleukin 4 (B-cell growth factor II/eosinophil differentiation factor) is a mitogen and differentiation factor for preactivated murine B lymphocytes. (1986) (49)
Pathogen-induced Th1 phenotype development in CD4+ alpha beta-TCR transgenic T cells is macrophage dependent. (1993) (46)
Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages (2013) (45)
B-cell-stimulatory factor 1 reverses Fc receptor-mediated inhibition of B-lymphocyte activation. (1987) (45)
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases (2019) (42)
Role of T Cell‐Derived Lymphokines in Two Models of B‐Cell Tolerance (1987) (40)
A 380-gene meta-signature of active tuberculosis compared with healthy controls (2016) (40)
In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity. (2004) (37)
T-cell differentiation: Commitment factors for T helper cells (2000) (37)
Lymphoma models for B cell activation and tolerance. VI. Reversal of anti-Ig-mediated negative signaling by T cell-derived lymphokines. (1987) (36)
NF-κB1 Inhibits TLR-Induced IFN-β Production in Macrophages through TPL-2–Dependent ERK Activation (2011) (36)
Regulation of Experimental Autoimmune Encephalomyelitis by TPL-2 Kinase (2014) (35)
Systems approaches to studying the immune response in tuberculosis. (2013) (35)
Critical Role of Type 1 Cytokines in Controlling Initial Infection with Burkholderia mallei (2006) (35)
The BCL1 B lymphoma responds to IL-4, IL-5, and GM-CSF. (1989) (34)
Regulatory T Cells + CD25+ CD4Regulatory Function to Naturally Occurring Express Foxp3 but Have Comparable IL-10-Secreting Regulatory T Cells Do Not (2004) (33)
A conditionally active form of STAT6 can mimic certain effects of IL-4. (1998) (33)
Are dendritic cells afraid of commitment? (2004) (32)
Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages (2016) (32)
Contribution of cytokines to pathology and protection in virus infection. (2011) (30)
Systems approach to understand the immune response in tuberculosis: an iterative process between mouse models and human disease. (2013) (30)
A T cell–myeloid IL-10 axis regulates pathogenic IFN-γ–dependent immunity in a mouse model of type 2–low asthma (2020) (28)
Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria (2017) (28)
Effects of cyclosporine on responses of murine B cells to T cell-derived lymphokines. (1986) (26)
Regula'ten' the gut (2007) (25)
Correction: Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers (2013) (23)
Breakpoints in immunoregulation required for Th1 cells to induce diabetes (2006) (22)
The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease (2015) (21)
Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (2018) (21)
Pillars Article: IL-10 Inhibits Cytokine Production by Activated Macrophages. J. Immunol. 1991. 147: 3815-3822. (2016) (20)
Establishing the follicular helper identity. (2009) (20)
Mouse gamma delta TCR+NK1.1+ thymocytes specifically produce interleukin-4, are major histocompatibility complex class I independent, and are developmentally related to alpha beta TCR+NK1.1+ thymocytes. (1996) (19)
Transcription Factors Directing Th2 Differentiation: Gata-3 Plays a Dominant Role (2016) (19)
Regulatory role of IL4 and other cytokines in T helper cell development in an αβ TCR transgenic mouse system (1993) (18)
The production of lymphokines by primary alloreactive T-cell clones: a co-ordinate analysis of 233 clones in seven lymphokine assays. (1985) (18)
Interleukin-10 in Health and Disease (2014) (18)
Immunology: Commit ye helpers (2000) (17)
Identification of the Key Differential Transcriptional Responses of Human Whole Blood Following TLR2 or TLR4 Ligation In-Vitro (2014) (16)
Commitment factors for T helper cells. (2000) (16)
Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis (2021) (16)
Immunity Benefits from a Little Suppression (2008) (16)
Author Correction: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (2019) (15)
GATA-Binding Protein Expression of the IL-5 Gene : A Role for a Nuclear Factors Conferring Th 2-Specific-Regulatory Elements and cis Characterization of (1998) (15)
Scalable and robust SARS-CoV-2 testing in an academic center (2020) (15)
High-Dose IL-2 Skews a Glucocorticoid-Driven IL-17+IL-10+ Memory CD4+ T Cell Response towards a Single IL-10–Producing Phenotype (2018) (13)
Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data (2021) (13)
A Novel Repertoire of Blood Transcriptome Modules Based on Co-expression Patterns Across Sixteen Disease and Physiological States (2019) (13)
Host-directed immunotherapy of viral and bacterial infections: past, present and future (2022) (13)
Interleukin-4 (B cell growth factor-II/eosinophil differentiation factor) is a mitogen and differentiation factor for preactivated murine B lymphocytes. (1986) (13)
Checkpoints in the regulation of T helper 1 responses. (2002) (11)
Constitutive production of lymphokines by cloned murine B-cell lymphomas--CH12 B lymphoma produces interleukin-4. (1989) (11)
Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure (2021) (11)
Multiple levels of regulation of Th2 cytokine gene expression. (1999) (10)
Interleukin-10: Cytokines in Anti-inflammation and Tolerance (2014) (10)
The science of infectious diseases (2014) (10)
Transcriptomic Characterization of Tuberculous Sputum Reveals a Host Warburg Effect and Microbial Cholesterol Catabolism (2020) (9)
The immunobiology of interleukin 4 (1993) (9)
Role of IL-10 and the IL-10 Receptor in Immune Responses (2014) (9)
Immunity and Tolerance (2013) (9)
Pillars Article: IL-10 Acts on the Antigen-presenting Cell to Inhibit Cytokine Production by Thl Cells. J. Immunol. 1991. 146: 3444-3451. (2016) (8)
Induces IL-10 Production in an IL-27 – Independent Manner and Blocks Responsiveness to IFN-g for Production of IL-12 and Bacterial Killing in Mycobacterium tuberculosis – Infected Macrophages (2014) (8)
Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling (2016) (8)
Regulating the regulator: Bhlhe40 directly keeps IL-10 in check (2018) (8)
Checkpoints for regulation of development and interferon gamma production by Th1 cells in TCR-transgenic models. (1998) (7)
Development and Characterization of a Fixed Repertoire of Blood Transcriptome Modules Based on Co-expression Patterns Across Immunological States (2019) (7)
Interleukin-10: An Inhibitor of Macrophage-Dependent Stimulation of Th1 Cells (1995) (7)
Mycobacterium tuberculosis and its ability to resist immunity. (2007) (6)
Preferentially Expressed in Th 2 But Not Th 1 Cutting Edge : The Chemokine Receptor CCR 8 Is (1998) (5)
MinireviewFurther Checkpoints in Th 1 Development of Th 1 responses (2002) (5)
Regulatory role of IL4 and other cytokines in T helper cell development in an alpha beta TCR transgenic mouse system. (1993) (5)
Interleukin-12 and up: functions of T helper subsets resulting from differential cytokine production. (1997) (4)
CD25CD4 T cells compete with naive CD4 T cells for IL-2 and exploit it for the induction of IL-10 production (2005) (4)
Blockade of IL-10 signaling during BCG vaccination enhances and sustains Th 1 , Th 17 , and innate lymphoid IFN-γ and IL-17 responses and increases protection to Mycobacterium tuberculosis infection (2012) (4)
Remembering Ralph Steinman (2011) (4)
Correction: Transcription Factors Directing Th2 Differentiation: Gata-3 Plays a Dominant Role (2016) (3)
Checkpoints for regulation of development and IFN-gamma production by Th1 cells in TCR-transgenic models. (1999) (3)
Development and function of IL-10-secreting regulatory T cells: Comparison with naturally occurring CD4+CD25+ regulatory T cells (2005) (3)
Cytokines in Tuberculosis (2017) (3)
A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (2019) (3)
Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease. (2020) (2)
Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production (2018) (2)
Infection Mycobacterium tuberculosis Protection to and IL-17 Responses and Increases γ IFN-Sustains Th 1 , Th 17 , and Innate Lymphoid Calmette-Guérin Vaccination Enhances and Blockade of IL-10 Signaling during Bacillus (2012) (2)
CD 25 1 CD 4 1 T cells compete with naive CD 4 1 T cells for IL-2 and exploit it for the induction of IL-10 production (2005) (2)
NF-κ B 1 Inhibits TLR-Induced IFN-β Production in Macrophages Through TPL-2-dependent ERK Activation 1 (2011) (2)
JEM women in STEM: Unique journeys with a common purpose (2020) (1)
Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease (2020) (1)
A 380 gene meta-signature of active TB compared to healthy controls (2016) (1)
Preferentially Expressed in Th2 But Not Th1 Cutting Edge: The Chemokine Receptor CCR8 Is (2012) (1)
Correction: TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages. (2022) (1)
Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center (2020) (1)
An interferon signature is associated with HAM/TSP but not viral containment in HTLV-1 infection (2011) (1)
Brief Definitive Report the Effect of Antigen Dose on Cd4 + T Helper Cell Phenotype Development in a T Cell Receptor-ol[3-transgenic Model (2003) (0)
Volume 109 ‐ Contents (2003) (0)
The Plasticity of Dendritic Cells Populations in Promoting Th‐cell Responses (2008) (0)
IL-10 producing Th I cells (2009) (0)
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis (2020) (0)
Regulation of the immune response to pathogens - part 1 of 2 (2012) (0)
Development of Th2 Cells T Cells to Enhance the + Effect on Naive CD4 ,25-Dihydroxyvitamin D3 Has a Direct a 1 (2001) (0)
Cytokines regulating the innate response (2009) (0)
Development of a Fixed Repertoire of Blood Transcriptome Modules Based on Co-expression Patterns Across Immunological States (2020) (0)
Tuberculosis screening: variations on a theme (2009) (0)
Regulation of the immune response to pathogens 2 (2012) (0)
SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 1; peer review: awaiting peer review] (2021) (0)
IL-1 a and TNF-a Are Required for IL-12-Induced Development of Th1 Cells Producing High Levels of IFN- g in BALB/c But Not C57BL/6 Mice (1998) (0)
Regulation and functional significance of T-cell subsets: edited by R.L. Coffman, Karger, 1992. £91.30/$169.00 (x + 218 pages) ISBN 3 8055 5577 6 (1993) (0)
Publisher Correction: c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells (2019) (0)
A change in blood transcriptional signatures accompanies successful tuberculosis therapy (2012) (0)
Interleukin-10. (2020) (0)
A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection (2018) (0)
Sustains Th1, Th17, and Innate Lymphoid Calmette-Guérin Vaccination Enhances and Blockade of IL-10 Signaling during Bacillus (2012) (0)
Systems Immunology: Approaches to Tuberculosis (2016) (0)
Characterisation Of A Whole Blood Transcriptional Signature Of Subclinical Tuberculosis Identified By Fdg-Pet/ct In Asymptomatic Hiv-1 Infected Adults (2014) (0)
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases (2019) (0)
Regulation of the immune response to pathogens 1 (2012) (0)
GATA-3-Mediated Th 2 Cell Development Cells and Functions As a Repressor of Friend of GATA Is Expressed in Naive (2002) (0)
The use of interleukin-10 analogs or antagonists for the treatment of endotoxin-induced toxicity taisuperantigeenin (1994) (0)
during Malaria Infection Protection from Severe Immunopathology T Cells: A Critical Mechanism for + Th1 CD4 IL-27 Promotes IL-10 Production by Effector (2011) (0)
Blood Transcriptional Phenotypes of Progressive Latent M. tuberculosis Infection Inform Novel Signatures That Improve Prediction of Tuberculosis Risk (2021) (0)
Antibody , a Potent Antagonist of IL-18 Binding and Function : Anti-IL-1 RAcPL IL-18 Receptors , Their Role in Ligand (2000) (0)
The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis (2018) (0)
CS10-1. Regulation Of The Immune Response In Tuberculosis: Lessons Learned From Mouse Models And Human Disease (2011) (0)
c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells (2018) (0)
AntiRANKL antibody maintains trabecular bone mineral density and increases cortical area in ovariectomized swiss-webster mice: A new therapy to counteract glucocorticoid-induced osteoporosis (2003) (0)
Cytokines and Macrophages and Dendritic Cells: Key Modulators of Immune Responses (2009) (0)
CS09-2. The Regulation of Interleukin 10 and Interleukin 12 in Macrophages (2011) (0)
Differential expression of an alternative splice variant of IL-12Rβ1 impacts early dissemination in the mouse and associates with disease outcome in both mouse and humans exposed to tuberculosis (2018) (0)
ID: 15: The probacterial activity of Type I interferons: a target for disease intervention? (2015) (0)
Calling British scientists abroad (1989) (0)
Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-g Signaling (2016) (0)
1 c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD 4 + T cells (2018) (0)
Driving change in tuberculosis research: an interview with Anne O’Garra (2013) (0)
Publisher Correction: c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells (2019) (0)
Editorial overview. (2012) (0)
This information is current as Role Differentiation : Gata-3 Plays a Dominant Transcription Factors Directing (2016) (0)
This information is current as Role Differentiation : Gata-3 Plays a Dominant Transcription Factors Directing (2016) (0)
Regulation of the immune response to pathogens - part 2 of 2 (2012) (0)
Ralph M. Steinman (1943–2011) (2011) (0)
David Aspergillus fumigatus Inhaled Immunocompetent Mice in Response to Cytokine Networking in Lungs of (2000) (0)
S37 Dual step interferon-gamma release assay testing can improve tuberculosis (TB) risk stratification in contacts of pulmonary TB: a prospective adult household contact cohort study (2021) (0)
Correction: Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein (1998) (0)
[18F]-FDG PET/CT characterisation of progressive HIV-associated tuberculosis (2016) (0)
TRIF-Dependent TLR Signals , and Produce IL-10 in Response to MyD 88-and but Not Plasmacytoid Dendritic Cells , Macrophages and Myeloid Dendritic Cells (2006) (0)
Responsiveness in Th 1 and Th 2 Cells Molecule ( SLAM ) : Differential Expression of Mouse Signaling Lymphocytic Activation Molecular and Functional Characterization (1999) (0)
Inflammation / Cytokines (SY3-5) Chairpersons: Toshio Hirano, Anne O'Garra (2010) (0)
Independently of IL-4 in CD 4 Locus IL-10 GATA-3 Directly Remodels (2006) (0)

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University of Oxford

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