Ann Marie Surprenant

Ann Marie Surprenant's AcademicInfluence.com Rankings

Medical

#2853

World Rank

#3295

Historical Rank

Pharmacology

#323

World Rank

#374

Historical Rank

medical Degrees

Download Badge

Medical

Ann Marie Surprenant's Degrees

PhD Pharmacology University of California, San Diego
Bachelors Pharmacology University of California, San Diego

Why Is Ann Marie Surprenant Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Ann Marie Surprenant's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Cytolytic P2Z Receptor for Extracellular ATP Identified as a P2X Receptor (P2X7) (1996) (1705)
Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor (2006) (1367)
A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP (1994) (1066)
Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons (1995) (1046)
Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels (1996) (891)
Rapid secretion of interleukin-1β by microvesicle shedding (2001) (788)
Pharmacology of cloned P2X receptors. (2000) (717)
5-HT3 receptors are membrane ion channels (1989) (646)
Mu and delta receptors belong to a family of receptors that are coupled to potassium channels. (1987) (602)
ATP mediates fast synaptic transmission in mammalian neurons (1992) (579)
Signaling at purinergic P2X receptors. (2009) (520)
Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals (1997) (435)
The Permeabilizing ATP Receptor, P2X7 (1997) (421)
Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. (1996) (418)
Pore dilation of neuronal P2X receptor channels (1999) (415)
An antagonist‐insensitive P2X receptor expressed in epithelia and brain. (1996) (413)
Rapid secretion of interleukin-1beta by microvesicle shedding. (2001) (408)
P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1β in Mouse Macrophage1 (2008) (406)
Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors. (2000) (404)
Proteomic and functional evidence for a P2X7 receptor signalling complex (2001) (399)
P2X3 is expressed by DRG neurons that terminate in inner lamina II (1998) (361)
Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor (1999) (354)
Nanoparticles can cause DNA damage across a cellular barrier. (2009) (353)
Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). (1995) (334)
Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor (1997) (326)
Pannexin-1 Couples to Maitotoxin- and Nigericin-induced Interleukin-1β Release through a Dye Uptake-independent Pathway* (2007) (301)
Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors. (1998) (283)
P2x receptors bring new structure to ligand-gated ion channels (1995) (277)
Ionic permeability of, and divalent cation effects on, two ATP‐gated cation channels (P2X receptors) expressed in mammalian cells. (1996) (276)
Reanalysis of P2X7 Receptor Expression in Rodent Brain (2004) (270)
Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells (2009) (269)
Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1β release through pyrophosphates (2009) (250)
Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues. (1998) (227)
Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes (2005) (222)
Identification of Amino Acid Residues Contributing to the ATP-binding Site of a Purinergic P2X Receptor* (2000) (215)
Electrophysiological properties of P2X‐purinoceptors in rat superior cervical, nodose and guinea‐pig coeliac neurones. (1995) (212)
Muscarinic M1 and M2 receptors mediate depolarization and presynaptic inhibition in guinea‐pig enteric nervous system. (1985) (212)
Subunit Arrangement in P2X Receptors (2003) (208)
Identification of amino acid residues contributing to the pore of a P2X receptor (1997) (206)
Cytosolic Ca2+, exocytosis, and endocytosis in single melanotrophs of the rat pituitary (1990) (204)
Different sensitivities to pH of ATP-induced currents at four cloned P2X receptors. (1997) (197)
P2X7 receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness (2011) (190)
Epithelial Membrane Proteins Induce Membrane Blebbing and Interact with the P2X7 Receptor C Terminus* (2002) (188)
Vasoconstriction of guinea‐pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP (1992) (176)
Inhibitory synaptic potentials resulting from alpha 2‐adrenoceptor activation in guinea‐pig submucous plexus neurones. (1985) (165)
Pseudoapoptosis Induced by Brief Activation of ATP-gated P2X7 Receptors* (2005) (161)
A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents. (1992) (160)
Inhibition of calcium currents by noradrenaline, somatostatin and opioids in guinea‐pig submucosal neurones. (1990) (159)
Calcium permeability and block at homomeric and heteromeric P2X2 and P2X3 receptors, and P2X receptors in rat nodose neurones (1998) (139)
Baculovirus Expression Provides Direct Evidence for Heteromeric Assembly of P2X2 and P2X3 Receptors (1997) (138)
The P2X7 receptor–pannexin connection to dye uptake and IL-1β release (2009) (138)
Pharmacological and biophysical properties of the human P2X5 receptor. (2003) (137)
Membrane Topology of an ATP-gated Ion Channel (P2X Receptor)* (1998) (135)
Characterization of a selective and potent antagonist of human P2X7 receptors, AZ11645373 (2006) (133)
Contribution of individual subunits to the multimeric P2X(2) receptor: estimates based on methanethiosulfonate block at T336C. (1999) (131)
Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions. (2010) (119)
Amino Acid Residues Involved in Gating Identified in the First Membrane-spanning Domain of the Rat P2X2 Receptor* (2001) (117)
Inhibition of Neutrophil Apoptosis by ATP Is Mediated by the P2Y11 Receptor1 (2007) (116)
P2X7 Receptor-Mediated Release of Cathepsins from Macrophages Is a Cytokine-Independent Mechanism Potentially Involved in Joint Diseases (2010) (116)
Neural reflexes controlling intestinal microcirculation. (1996) (114)
N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X7 receptors (2005) (113)
The antagonist trinitrophenyl‐ATP reveals co‐existence of distinct P2X receptor channels in rat nodose neurones (1998) (112)
Differential Assembly of Rat Purinergic P2X7 Receptor in Immune Cells of the Brain and Periphery* (2001) (111)
Amino Acid Residues in the P2X7 Receptor that Mediate Differential Sensitivity to ATP and BzATP (2007) (109)
Facilitation of P2X7 Receptor Currents and Membrane Blebbing via Constitutive and Dynamic Calmodulin Binding (2008) (108)
Functional and Molecular Diversity of Purinergic Ion Channel Receptors (1999) (105)
Vasodilatation of arterioles by acetylcholine released from single neurones in the guinea‐pig submucosal plexus. (1990) (102)
Tyrosine Phosphorylation of HSP90 within the P2X7 Receptor Complex Negatively Regulates P2X7 Receptors* (2003) (100)
Pannexin 1 forms an anion-selective channel (2012) (99)
P2X4, P2Y1 and P2Y2 receptors on rat alveolar macrophages (2003) (98)
2′,3′‐O‐(2,4,6‐ trinitrophenyl) adenosine 5′‐triphosphate (TNP‐ATP)–a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels (1998) (95)
Dopamine actions on calcium currents, potassium currents and hormone release in rat melanotrophs. (1991) (94)
P2X1 receptor activation in HL60 cells. (1996) (92)
Role of Ectodomain Lysines in the Subunits of the Heteromeric P2X2/3 Receptor (2006) (92)
Functional properties of heteromeric P2X(1/5) receptors expressed in HEK cells and excitatory junction potentials in guinea-pig submucosal arterioles. (2000) (88)
P2X receptors in autonomic and sensory neurons (1996) (71)
Differential localization of 5-HT1 receptors on myenteric and submucosal neurons. (1988) (70)
Enhanced adenosine triphosphate release from the urothelium of patients with painful bladder syndrome: a possible pathophysiological explanation. (2007) (68)
Cation current activated by hyperpolarization (IH) in guinea pig enteric neurons. (1990) (67)
A study on P2x purinoceptors mediating the electrophysiological and contractile effects of purine nucleotides in rat vas deferens (1995) (65)
C-terminal Calmodulin-binding Motif Differentially Controls Human and Rat P2X7 Receptor Current Facilitation* (2010) (64)
Identification of Key Residues Coordinating Functional Inhibition of P2X7 Receptors by Zinc and Copper (2008) (63)
Effects of 5‐HT3 receptor antagonists on 5‐HT and nicotinic depolarizations in guinea‐pig submucosal neurones (1990) (61)
P2X receptor characterization and IL‐1/IL‐1Ra release from human endothelial cells (2007) (61)
Trinitrophenyl-Substituted Nucleotides Are Potent Antagonists Selective for P 2 X 1 , P 2 X 3 , and Heteromeric P 2 X 2 / 3 Receptors (1998) (58)
Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation (2009) (57)
N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X(7) receptors. (2005) (57)
Cholera toxin-sensitive neurons in guinea pig submucosal plexus. (1993) (56)
Potassium channels opened by noradrenaline and other transmitters in excised membrane patches of guinea‐pig submucosal neurones. (1992) (56)
Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors (2002) (56)
Adenosine A1 and A2 receptors mediate presynaptic inhibition and postsynaptic excitation in guinea pig submucosal neurons. (1991) (53)
Ligand binding to the serotonin 5HT3 receptor studied with a novel fluorescent ligand. (1998) (51)
Mucosal stimulation evokes vasodilation in submucosal arterioles by neuronal and nonneuronal mechanisms. (1993) (51)
μ-Opioid receptors andα2-Adrenoceptors coexist on myenteric but not on submucous neurones (1985) (51)
Common ionic mechanisms of excitation by substance P and other transmitters in guinea‐pig submucosal neurones. (1993) (51)
Potassium currents and their modulation by muscarine and substance P in neuronal cultures from adult guinea pig celiac ganglia. (1993) (50)
Purinergic P2Y2 Receptors Induce Increased MCP-1/CCL2 Synthesis and Release from Rat Alveolar and Peritoneal Macrophages1 (2007) (48)
Substance P mediates neurogenic vasodilatation in extrinsically denervated guinea‐pig submucosal arterioles. (1990) (47)
Somatostatin‐mediated inhibitory postsynaptic potential in sympathetically denervated guinea‐pig submucosal neurones. (1993) (46)
Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor. (2001) (46)
Morphological properties and projections of electrophysiologically characterized neurons in the guinea-pig submucosal plexus (1994) (46)
Identification of Thr283 as a key determinant of P2X7 receptor function (2006) (45)
Mechanisms underlying presynaptic inhibition through alpha 2‐adrenoceptors in guinea‐pig submucosal neurones. (1990) (43)
Characterization of vasopressin actions in isolated submucosal arterioles of the intestinal microcirculation. (1990) (42)
Expression of ligand-gated ion channels with the Semliki Forest virus expression system. (1997) (41)
Characterization of ATP-gated P2X7 receptors in fish provides new insights into the mechanism of release of the leaderless cytokine interleukin-1 beta. (2007) (38)
Cholinergic and noncholinergic submucosal neurons dilate arterioles in guinea pig colon. (1991) (37)
Functional characterization of neuronal pre and postsynaptic α2‐adrenoceptor subtypes in guinea‐pig submucosal plexus (1990) (36)
Identification of the amino acid residues in the extracellular domain of rat P2X7 receptor involved in functional inhibition by acidic pH (2009) (34)
A comparison of the binding characteristics of recombinant P2×1 and P2×2 purinoceptors (1996) (34)
Observations on the actions of substance P and [d-Arg1, d-Pro2, d-Trp7,9,Leu11]substance P on single neurons of the guinea pig submucous plexus (1987) (33)
The binding characteristics of a human bladder recombinant P2X purinoceptor, labelled with [3H]‐αβmeATP, [35S]‐ATPγS or 33[P]‐ATP (1996) (32)
A novel and efficient method for the stable expression of heteromeric ion channels in mammalian cells. (1998) (29)
Quinine blocks a calcium‐activated potassium conductance in mammalian enteric neurones (1984) (27)
Single channel properties of the 5-HT3 subtype of serotonin receptor in primary cultures of rodent hippocampus (1994) (27)
New insights on P2X purinoceptors (1995) (23)
Increased P2X7R expression in atrial cardiomyocytes of caveolin-1 deficient mice (2010) (20)
Effects of phospholipase A2 inhibitors on coupling of α2‐adrenoceptors to inwardly rectifying potassium currents in guinea‐pig submucosal neurones (1993) (19)
Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy. (1992) (19)
N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P 2 X 7 receptors (2005) (18)
Biosynthesis of multiple forms of β-endorphin in the reptile intermediate pituitary (1983) (18)
Interaction between cysteines introduced into each transmembrane domain of the rat P2X2 receptor (2003) (18)
A comparative study of neuromuscular transmission in several mammalian muscular arteries (1980) (17)
Sustained Depolarization and ADP-Ribose Activate a Common Ionic Current in Rat Peritoneal Macrophages 1 (2003) (17)
Subunit Arrangement in P 2 X Receptors (2003) (17)
New insights on P 2 x purinoceptors (16)
Re-innervation of submucosal arterioles by myenteric neurones following extrinsic denervation. (1992) (14)
DTG and (+)-3-PPP inhibit a ligand-activated hyperpolarization in mammalian neurons. (1989) (13)
The selective P2X purinoceptor agonist, β,γ-methylene-L-adenosine 5′-triphosphate, discriminates between smooth muscle and neuronal P2X purinoceptors (1995) (11)
ATP in synapses (1993) (11)
Effects of nifedipine on nerve-evoked action potentials and consequent contractions in rat tail artery (1983) (10)
The selective P2X purinoceptor agonist, beta,gamma-methylene-L-adenosine 5'-triphosphate, discriminates between smooth muscle and neuronal P2X purinoceptors. (1995) (10)
Binding thermodynamic characterization of human P2X1 and P2X3 purinergic receptors. (2008) (9)
Pain TRP‐ed up by PARs (2007) (9)
Noradrenaline, somatostatin and opioids inhibit activity of single HVA/N-type calcium channels in excised neuronal membranes (1991) (9)
mu-Opioid receptors and alpha 2-adrenoceptors coexist on myenteric but not on submucous neurones. (1985) (8)
The binding characteristics of a human bladder recombinant P2X purinoceptor, labelled with [3H]-alpha beta meATP, [35S]-ATP gamma S or [33P]-ATP. (1996) (6)
In vitro synthesis of ACTH- and beta-endorphin-related substances in the pars distalis of Anolis carolinensis. (1984) (5)
Cloned and Expressed (1998) (4)
Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1b release through pyrophosphates This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourceare (2009) (3)
P2RX7 (purinergic receptor P2X, ligand-gated ion channel, 7) (2011) (2)
P2X Purinergic Receptors (2004) (2)
Muscarinic Receptors on Neurones of the Submucous Plexus (1985) (1)
Effects of notexin on neuromuscular transmission in the guinea pig vas deferens. (1990) (1)
Enhanced ATP release from the urothelium of patients with painful bladder syndrome: A possible pathophysiological explanation (2007) (1)
Pannexin 1 forms an anion-selective channel (2012) (0)
Table of Contents (1996) (0)
Mediated by the P 2 Y Inhibition of Neutrophil Apoptosis by ATP Is (2007) (0)
Cholinergic neurones in the submucosal plexus mediate reflex vasodilation in guinea pig ileum (1991) (0)
Purinergic Receptors in the CNS (1999) (0)
Discrete regions of the P2X 7 receptor confer differential sensitivity to ATP and BzATP (2007) (0)
Poster Abstracts—Wednesday June 2, 2004PRO-INFLAMMATORY CYTOKINE MODULATION OF P2X RECEPTOR EXPRESSION IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS (2004) (0)
Renal Physiology (2001) (0)
Signal Transduction Processes in Sensorimotor Neurons of the Enteric Nervous System (1994) (0)
Potentially Involved in Joint Diseases Cytokine-Independent Mechanism Cathepsins from Macrophages Is a Receptor-Mediated Release of 7 P 2 X (2010) (0)
Observations on single ion channels affected by inhibitory transmitters in guinea pig submucous plexus neurones (1991) (0)
g and 6 receptors belong to a family of receptors that are coupled to potassium channels ( opioids / neuron / potassium conductance / guanine nucleotide-binding regulatory proteins / narcotic drugs (0)
ExperimentalSurgeryGroup,UniversityHospital"VirgendelaArrixaca"-FFIS,CarreteraPalmar,30120 Murcia, Spain (2010) (0)
Rat Alveolar and Peritoneal Macrophages MCP-1 / CCL 2 Synthesis and Release from Receptors Induce Increased 2 Purinergic P 2 Y (2007) (0)
Calcium block of a novel ATP-gated ion channel expressed in spinal cord and immune cells (1996) (0)
Co-immunoprecipitation of P2X receptor subunits from rat tissues (2002) (0)
The P2x7 -Hsp90 relationship: a matter of tyrosine phosphorylation? (2002) (0)
PRO-INFLAMMATORY CYTOKINE MODULATION OF P2X RECEPTOR EXPRESSION IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS (2004) (0)
Extracellular H62 and D197 mediate functional inhibition of P2X 7 receptor by zinc (2007) (0)
Peritoneal Macrophages Activate a Common Ionic Current in Rat Sustained Depolarization and ADP-Ribose (2003) (0)
Muscarinic Receptors on N eurones of the Submucous Plexus * (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Ann Marie Surprenant?

Ann Marie Surprenant is affiliated with the following schools: