Ann Marie Surprenant
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Ann Marie Surprenantmedical Degrees
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Pharmacology
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Ann Marie Surprenant's Degrees
- PhD Pharmacology University of California, San Diego
- Bachelors Pharmacology University of California, San Diego
Why Is Ann Marie Surprenant Influential?
(Suggest an Edit or Addition)Ann Marie Surprenant's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Cytolytic P2Z Receptor for Extracellular ATP Identified as a P2X Receptor (P2X7) (1996) (1705)
- Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor (2006) (1367)
- A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP (1994) (1066)
- Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons (1995) (1046)
- Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels (1996) (891)
- Rapid secretion of interleukin-1β by microvesicle shedding (2001) (788)
- Pharmacology of cloned P2X receptors. (2000) (717)
- 5-HT3 receptors are membrane ion channels (1989) (646)
- Mu and delta receptors belong to a family of receptors that are coupled to potassium channels. (1987) (602)
- ATP mediates fast synaptic transmission in mammalian neurons (1992) (579)
- Signaling at purinergic P2X receptors. (2009) (520)
- Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals (1997) (435)
- The Permeabilizing ATP Receptor, P2X7 (1997) (421)
- Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. (1996) (418)
- Pore dilation of neuronal P2X receptor channels (1999) (415)
- An antagonist‐insensitive P2X receptor expressed in epithelia and brain. (1996) (413)
- Rapid secretion of interleukin-1beta by microvesicle shedding. (2001) (408)
- P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1β in Mouse Macrophage1 (2008) (406)
- Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors. (2000) (404)
- Proteomic and functional evidence for a P2X7 receptor signalling complex (2001) (399)
- P2X3 is expressed by DRG neurons that terminate in inner lamina II (1998) (361)
- Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor (1999) (354)
- Nanoparticles can cause DNA damage across a cellular barrier. (2009) (353)
- Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). (1995) (334)
- Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor (1997) (326)
- Pannexin-1 Couples to Maitotoxin- and Nigericin-induced Interleukin-1β Release through a Dye Uptake-independent Pathway* (2007) (301)
- Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors. (1998) (283)
- P2x receptors bring new structure to ligand-gated ion channels (1995) (277)
- Ionic permeability of, and divalent cation effects on, two ATP‐gated cation channels (P2X receptors) expressed in mammalian cells. (1996) (276)
- Reanalysis of P2X7 Receptor Expression in Rodent Brain (2004) (270)
- Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells (2009) (269)
- Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1β release through pyrophosphates (2009) (250)
- Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues. (1998) (227)
- Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes (2005) (222)
- Identification of Amino Acid Residues Contributing to the ATP-binding Site of a Purinergic P2X Receptor* (2000) (215)
- Electrophysiological properties of P2X‐purinoceptors in rat superior cervical, nodose and guinea‐pig coeliac neurones. (1995) (212)
- Muscarinic M1 and M2 receptors mediate depolarization and presynaptic inhibition in guinea‐pig enteric nervous system. (1985) (212)
- Subunit Arrangement in P2X Receptors (2003) (208)
- Identification of amino acid residues contributing to the pore of a P2X receptor (1997) (206)
- Cytosolic Ca2+, exocytosis, and endocytosis in single melanotrophs of the rat pituitary (1990) (204)
- Different sensitivities to pH of ATP-induced currents at four cloned P2X receptors. (1997) (197)
- P2X7 receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness (2011) (190)
- Epithelial Membrane Proteins Induce Membrane Blebbing and Interact with the P2X7 Receptor C Terminus* (2002) (188)
- Vasoconstriction of guinea‐pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP (1992) (176)
- Inhibitory synaptic potentials resulting from alpha 2‐adrenoceptor activation in guinea‐pig submucous plexus neurones. (1985) (165)
- Pseudoapoptosis Induced by Brief Activation of ATP-gated P2X7 Receptors* (2005) (161)
- A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents. (1992) (160)
- Inhibition of calcium currents by noradrenaline, somatostatin and opioids in guinea‐pig submucosal neurones. (1990) (159)
- Calcium permeability and block at homomeric and heteromeric P2X2 and P2X3 receptors, and P2X receptors in rat nodose neurones (1998) (139)
- Baculovirus Expression Provides Direct Evidence for Heteromeric Assembly of P2X2 and P2X3 Receptors (1997) (138)
- The P2X7 receptor–pannexin connection to dye uptake and IL-1β release (2009) (138)
- Pharmacological and biophysical properties of the human P2X5 receptor. (2003) (137)
- Membrane Topology of an ATP-gated Ion Channel (P2X Receptor)* (1998) (135)
- Characterization of a selective and potent antagonist of human P2X7 receptors, AZ11645373 (2006) (133)
- Contribution of individual subunits to the multimeric P2X(2) receptor: estimates based on methanethiosulfonate block at T336C. (1999) (131)
- Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions. (2010) (119)
- Amino Acid Residues Involved in Gating Identified in the First Membrane-spanning Domain of the Rat P2X2 Receptor* (2001) (117)
- Inhibition of Neutrophil Apoptosis by ATP Is Mediated by the P2Y11 Receptor1 (2007) (116)
- P2X7 Receptor-Mediated Release of Cathepsins from Macrophages Is a Cytokine-Independent Mechanism Potentially Involved in Joint Diseases (2010) (116)
- Neural reflexes controlling intestinal microcirculation. (1996) (114)
- N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X7 receptors (2005) (113)
- The antagonist trinitrophenyl‐ATP reveals co‐existence of distinct P2X receptor channels in rat nodose neurones (1998) (112)
- Differential Assembly of Rat Purinergic P2X7 Receptor in Immune Cells of the Brain and Periphery* (2001) (111)
- Amino Acid Residues in the P2X7 Receptor that Mediate Differential Sensitivity to ATP and BzATP (2007) (109)
- Facilitation of P2X7 Receptor Currents and Membrane Blebbing via Constitutive and Dynamic Calmodulin Binding (2008) (108)
- Functional and Molecular Diversity of Purinergic Ion Channel Receptors (1999) (105)
- Vasodilatation of arterioles by acetylcholine released from single neurones in the guinea‐pig submucosal plexus. (1990) (102)
- Tyrosine Phosphorylation of HSP90 within the P2X7 Receptor Complex Negatively Regulates P2X7 Receptors* (2003) (100)
- Pannexin 1 forms an anion-selective channel (2012) (99)
- P2X4, P2Y1 and P2Y2 receptors on rat alveolar macrophages (2003) (98)
- 2′,3′‐O‐(2,4,6‐ trinitrophenyl) adenosine 5′‐triphosphate (TNP‐ATP)–a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels (1998) (95)
- Dopamine actions on calcium currents, potassium currents and hormone release in rat melanotrophs. (1991) (94)
- P2X1 receptor activation in HL60 cells. (1996) (92)
- Role of Ectodomain Lysines in the Subunits of the Heteromeric P2X2/3 Receptor (2006) (92)
- Functional properties of heteromeric P2X(1/5) receptors expressed in HEK cells and excitatory junction potentials in guinea-pig submucosal arterioles. (2000) (88)
- P2X receptors in autonomic and sensory neurons (1996) (71)
- Differential localization of 5-HT1 receptors on myenteric and submucosal neurons. (1988) (70)
- Enhanced adenosine triphosphate release from the urothelium of patients with painful bladder syndrome: a possible pathophysiological explanation. (2007) (68)
- Cation current activated by hyperpolarization (IH) in guinea pig enteric neurons. (1990) (67)
- A study on P2x purinoceptors mediating the electrophysiological and contractile effects of purine nucleotides in rat vas deferens (1995) (65)
- C-terminal Calmodulin-binding Motif Differentially Controls Human and Rat P2X7 Receptor Current Facilitation* (2010) (64)
- Identification of Key Residues Coordinating Functional Inhibition of P2X7 Receptors by Zinc and Copper (2008) (63)
- Effects of 5‐HT3 receptor antagonists on 5‐HT and nicotinic depolarizations in guinea‐pig submucosal neurones (1990) (61)
- P2X receptor characterization and IL‐1/IL‐1Ra release from human endothelial cells (2007) (61)
- Trinitrophenyl-Substituted Nucleotides Are Potent Antagonists Selective for P 2 X 1 , P 2 X 3 , and Heteromeric P 2 X 2 / 3 Receptors (1998) (58)
- Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation (2009) (57)
- N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X(7) receptors. (2005) (57)
- Cholera toxin-sensitive neurons in guinea pig submucosal plexus. (1993) (56)
- Potassium channels opened by noradrenaline and other transmitters in excised membrane patches of guinea‐pig submucosal neurones. (1992) (56)
- Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors (2002) (56)
- Adenosine A1 and A2 receptors mediate presynaptic inhibition and postsynaptic excitation in guinea pig submucosal neurons. (1991) (53)
- Ligand binding to the serotonin 5HT3 receptor studied with a novel fluorescent ligand. (1998) (51)
- Mucosal stimulation evokes vasodilation in submucosal arterioles by neuronal and nonneuronal mechanisms. (1993) (51)
- μ-Opioid receptors andα2-Adrenoceptors coexist on myenteric but not on submucous neurones (1985) (51)
- Common ionic mechanisms of excitation by substance P and other transmitters in guinea‐pig submucosal neurones. (1993) (51)
- Potassium currents and their modulation by muscarine and substance P in neuronal cultures from adult guinea pig celiac ganglia. (1993) (50)
- Purinergic P2Y2 Receptors Induce Increased MCP-1/CCL2 Synthesis and Release from Rat Alveolar and Peritoneal Macrophages1 (2007) (48)
- Substance P mediates neurogenic vasodilatation in extrinsically denervated guinea‐pig submucosal arterioles. (1990) (47)
- Somatostatin‐mediated inhibitory postsynaptic potential in sympathetically denervated guinea‐pig submucosal neurones. (1993) (46)
- Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor. (2001) (46)
- Morphological properties and projections of electrophysiologically characterized neurons in the guinea-pig submucosal plexus (1994) (46)
- Identification of Thr283 as a key determinant of P2X7 receptor function (2006) (45)
- Mechanisms underlying presynaptic inhibition through alpha 2‐adrenoceptors in guinea‐pig submucosal neurones. (1990) (43)
- Characterization of vasopressin actions in isolated submucosal arterioles of the intestinal microcirculation. (1990) (42)
- Expression of ligand-gated ion channels with the Semliki Forest virus expression system. (1997) (41)
- Characterization of ATP-gated P2X7 receptors in fish provides new insights into the mechanism of release of the leaderless cytokine interleukin-1 beta. (2007) (38)
- Cholinergic and noncholinergic submucosal neurons dilate arterioles in guinea pig colon. (1991) (37)
- Functional characterization of neuronal pre and postsynaptic α2‐adrenoceptor subtypes in guinea‐pig submucosal plexus (1990) (36)
- Identification of the amino acid residues in the extracellular domain of rat P2X7 receptor involved in functional inhibition by acidic pH (2009) (34)
- A comparison of the binding characteristics of recombinant P2×1 and P2×2 purinoceptors (1996) (34)
- Observations on the actions of substance P and [d-Arg1, d-Pro2, d-Trp7,9,Leu11]substance P on single neurons of the guinea pig submucous plexus (1987) (33)
- The binding characteristics of a human bladder recombinant P2X purinoceptor, labelled with [3H]‐αβmeATP, [35S]‐ATPγS or 33[P]‐ATP (1996) (32)
- A novel and efficient method for the stable expression of heteromeric ion channels in mammalian cells. (1998) (29)
- Quinine blocks a calcium‐activated potassium conductance in mammalian enteric neurones (1984) (27)
- Single channel properties of the 5-HT3 subtype of serotonin receptor in primary cultures of rodent hippocampus (1994) (27)
- New insights on P2X purinoceptors (1995) (23)
- Increased P2X7R expression in atrial cardiomyocytes of caveolin-1 deficient mice (2010) (20)
- Effects of phospholipase A2 inhibitors on coupling of α2‐adrenoceptors to inwardly rectifying potassium currents in guinea‐pig submucosal neurones (1993) (19)
- Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy. (1992) (19)
- N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P 2 X 7 receptors (2005) (18)
- Biosynthesis of multiple forms of β-endorphin in the reptile intermediate pituitary (1983) (18)
- Interaction between cysteines introduced into each transmembrane domain of the rat P2X2 receptor (2003) (18)
- A comparative study of neuromuscular transmission in several mammalian muscular arteries (1980) (17)
- Sustained Depolarization and ADP-Ribose Activate a Common Ionic Current in Rat Peritoneal Macrophages 1 (2003) (17)
- Subunit Arrangement in P 2 X Receptors (2003) (17)
- New insights on P 2 x purinoceptors (16)
- Re-innervation of submucosal arterioles by myenteric neurones following extrinsic denervation. (1992) (14)
- DTG and (+)-3-PPP inhibit a ligand-activated hyperpolarization in mammalian neurons. (1989) (13)
- The selective P2X purinoceptor agonist, β,γ-methylene-L-adenosine 5′-triphosphate, discriminates between smooth muscle and neuronal P2X purinoceptors (1995) (11)
- ATP in synapses (1993) (11)
- Effects of nifedipine on nerve-evoked action potentials and consequent contractions in rat tail artery (1983) (10)
- The selective P2X purinoceptor agonist, beta,gamma-methylene-L-adenosine 5'-triphosphate, discriminates between smooth muscle and neuronal P2X purinoceptors. (1995) (10)
- Binding thermodynamic characterization of human P2X1 and P2X3 purinergic receptors. (2008) (9)
- Pain TRP‐ed up by PARs (2007) (9)
- Noradrenaline, somatostatin and opioids inhibit activity of single HVA/N-type calcium channels in excised neuronal membranes (1991) (9)
- mu-Opioid receptors and alpha 2-adrenoceptors coexist on myenteric but not on submucous neurones. (1985) (8)
- The binding characteristics of a human bladder recombinant P2X purinoceptor, labelled with [3H]-alpha beta meATP, [35S]-ATP gamma S or [33P]-ATP. (1996) (6)
- In vitro synthesis of ACTH- and beta-endorphin-related substances in the pars distalis of Anolis carolinensis. (1984) (5)
- Cloned and Expressed (1998) (4)
- Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1b release through pyrophosphates This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourceare (2009) (3)
- P2RX7 (purinergic receptor P2X, ligand-gated ion channel, 7) (2011) (2)
- P2X Purinergic Receptors (2004) (2)
- Muscarinic Receptors on Neurones of the Submucous Plexus (1985) (1)
- Effects of notexin on neuromuscular transmission in the guinea pig vas deferens. (1990) (1)
- Enhanced ATP release from the urothelium of patients with painful bladder syndrome: A possible pathophysiological explanation (2007) (1)
- Pannexin 1 forms an anion-selective channel (2012) (0)
- Table of Contents (1996) (0)
- Mediated by the P 2 Y Inhibition of Neutrophil Apoptosis by ATP Is (2007) (0)
- Cholinergic neurones in the submucosal plexus mediate reflex vasodilation in guinea pig ileum (1991) (0)
- Purinergic Receptors in the CNS (1999) (0)
- Discrete regions of the P2X 7 receptor confer differential sensitivity to ATP and BzATP (2007) (0)
- Poster Abstracts—Wednesday June 2, 2004PRO-INFLAMMATORY CYTOKINE MODULATION OF P2X RECEPTOR EXPRESSION IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS (2004) (0)
- Renal Physiology (2001) (0)
- Signal Transduction Processes in Sensorimotor Neurons of the Enteric Nervous System (1994) (0)
- Potentially Involved in Joint Diseases Cytokine-Independent Mechanism Cathepsins from Macrophages Is a Receptor-Mediated Release of 7 P 2 X (2010) (0)
- Observations on single ion channels affected by inhibitory transmitters in guinea pig submucous plexus neurones (1991) (0)
- g and 6 receptors belong to a family of receptors that are coupled to potassium channels ( opioids / neuron / potassium conductance / guanine nucleotide-binding regulatory proteins / narcotic drugs (0)
- ExperimentalSurgeryGroup,UniversityHospital"VirgendelaArrixaca"-FFIS,CarreteraPalmar,30120 Murcia, Spain (2010) (0)
- Rat Alveolar and Peritoneal Macrophages MCP-1 / CCL 2 Synthesis and Release from Receptors Induce Increased 2 Purinergic P 2 Y (2007) (0)
- Calcium block of a novel ATP-gated ion channel expressed in spinal cord and immune cells (1996) (0)
- Co-immunoprecipitation of P2X receptor subunits from rat tissues (2002) (0)
- The P2x7 -Hsp90 relationship: a matter of tyrosine phosphorylation? (2002) (0)
- PRO-INFLAMMATORY CYTOKINE MODULATION OF P2X RECEPTOR EXPRESSION IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS (2004) (0)
- Extracellular H62 and D197 mediate functional inhibition of P2X 7 receptor by zinc (2007) (0)
- Peritoneal Macrophages Activate a Common Ionic Current in Rat Sustained Depolarization and ADP-Ribose (2003) (0)
- Muscarinic Receptors on N eurones of the Submucous Plexus * (0)
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What Schools Are Affiliated With Ann Marie Surprenant?
Ann Marie Surprenant is affiliated with the following schools: