Anthony A. Hyman
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British biologist, Max Planck Institute of Cell Biology & Genetics
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Why Is Anthony A. Hyman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Anthony Arie Hyman is a British scientist and director at the Max Planck Institute of Molecular Cell Biology and Genetics. Early life and education Hyman was born in 1962, the eldest of three children of R. Anthony Hyman, a historian of computing, and Hon. Laura Alice Boyd, daughter of the 6th Baron Kilmarnock. He was educated at William Ellis School and St Marylebone Grammar School, University College London and the University of Cambridge, where he was awarded a PhD in 1987.
Anthony A. Hyman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biomolecular condensates: organizers of cellular biochemistry (2017) (2725)
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation (2009) (1853)
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation (2015) (1752)
- Liquid-liquid phase separation in biology. (2014) (1743)
- Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts (1996) (980)
- A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances (2015) (977)
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins (2018) (975)
- Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. (1992) (912)
- Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans (2005) (912)
- Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III (2000) (906)
- Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes (2011) (866)
- Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes (2010) (811)
- Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers (2010) (754)
- Dynamics and mechanics of the microtubule plus end (2003) (745)
- Preparation of modified tubulins. (1991) (678)
- RNA buffers the phase separation behavior of prion-like RNA binding proteins (2018) (656)
- BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals (2008) (619)
- Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding (2011) (572)
- The spindle: a dynamic assembly of microtubules and motors (2001) (543)
- ATP as a biological hydrotrope (2017) (537)
- Tau protein liquid–liquid phase separation can initiate tau aggregation (2018) (523)
- Rab5 regulates motility of early endosomes on microtubules (1999) (512)
- XMAP215 Is a Processive Microtubule Polymerase (2008) (500)
- Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo (2001) (498)
- Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins (2010) (493)
- Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3β phosphorylation (2001) (462)
- Functional Analysis of Kinetochore Assembly in Caenorhabditis elegans (2001) (458)
- Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans (2001) (453)
- Cytoplasmic Dynein Is Required for Distinct Aspects of Mtoc Positioning, Including Centrosome Separation, in the One Cell Stage Caenorhabditis elegans Embryo (1999) (451)
- The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. (1999) (447)
- Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions (2010) (442)
- Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts (1990) (438)
- Visualizing the molecular sociology at the HeLa cell nuclear periphery (2016) (428)
- Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner (2006) (427)
- The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin (2017) (427)
- Phase separation of a yeast prion protein promotes cellular fitness (2018) (424)
- RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation (2020) (382)
- Centriole assembly in Caenorhabditis elegans (2006) (373)
- The Distribution of Active Force Generators Controls Mitotic Spindle Position (2003) (369)
- Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP. (1992) (367)
- Ki-67 acts as a biological surfactant to disperse mitotic chromosomes (2016) (367)
- Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl (2010) (360)
- Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization (1997) (355)
- Determination of cell division axes in the early embryogenesis of Caenorhabditis elegans (1987) (350)
- Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts (1999) (338)
- A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility (2013) (336)
- Mitosis : a subject collection from Cold Spring Harbor Perspectives in biology (2015) (333)
- SAS-4 Is a C. elegans Centriolar Protein that Controls Centrosome Size (2003) (319)
- Genome-scale RNAi profiling of cell division in human tissue culture cells (2007) (314)
- Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells (2010) (312)
- An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function (2017) (308)
- Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods (2011) (305)
- Microtubule polymerases and depolymerases. (2007) (301)
- Morphogenetic Properties of Microtubules and Mitotic Spindle Assembly (1996) (296)
- Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing (2021) (288)
- Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis (2005) (287)
- Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis (2005) (272)
- A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos (1997) (261)
- Amyloid-like Self-Assembly of a Cellular Compartment (2016) (257)
- Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast (2005) (255)
- Polarization of PAR Proteins by Advective Triggering of a Pattern-Forming System (2011) (254)
- KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans. (2003) (254)
- Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism (2016) (253)
- Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position (1989) (253)
- A Genome-Scale Resource for In Vivo Tag-Based Protein Function Exploration in C. elegans (2012) (253)
- The Caenorhabditis elegans Centrosomal Protein SPD-2 Is Required for both Pericentriolar Material Recruitment and Centriole Duplication (2004) (250)
- Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics (2012) (249)
- Asymmetric cell division in C. elegans: cortical polarity and spindle positioning. (2004) (246)
- Pericentriolar material structure and dynamics (2014) (242)
- HAUS, the 8-Subunit Human Augmin Complex, Regulates Centrosome and Spindle Integrity (2009) (240)
- Growth and division of active droplets provides a model for protocells (2016) (239)
- Coupling cell division and cell death to microtubule dynamics. (1997) (237)
- Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans. (2011) (236)
- Structural changes accompanying GTP hydrolysis in microtubules: information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)- methylene-diphosphonate (1995) (232)
- A cytokinesis furrow is positioned by two consecutive signals (2005) (232)
- Reconstitution of Physiological Microtubule Dynamics Using Purified Components (2001) (231)
- Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules (1997) (231)
- Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos (2004) (225)
- Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo. (2005) (222)
- Spindle positioning by cortical pulling forces. (2005) (222)
- Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase (2017) (217)
- Pheromone Induces Programmed Cell Death in S. cerevisiae (2002) (217)
- The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is γ-tubulin dependent (2002) (216)
- BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures (2012) (212)
- Identification of essential components of the S. cerevisiae kinetochore (1993) (211)
- Two different microtubule-based motor activities with opposite polarities in kinetochores (1991) (211)
- Structural changes at microtubule ends accompanying GTP hydrolysis: Information from a slowly hydrolyzable analogue of GTP, guanylyl (α,β)methylenediphosphonate (1998) (205)
- A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis (2008) (199)
- Beyond Oil and Water—Phase Transitions in Cells (2012) (199)
- Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A (2008) (197)
- The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae (2005) (196)
- Are aberrant phase transitions a driver of cellular aging? (2016) (195)
- A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue (2011) (194)
- A recombineering pipeline for functional genomics applied to Caenorhabditis elegans (2006) (193)
- The human cap-binding complex is functionally connected to the nuclear RNA exosome (2013) (188)
- Partitioning of cancer therapeutics in nuclear condensates (2020) (187)
- Straight GDP-Tubulin Protofilaments Form in the Presence of Taxol (2007) (185)
- CDK1 Inactivation Regulates Anaphase Spindle Dynamics and Cytokinesis In Vivo (1997) (182)
- MaxSynBio: Avenues Towards Creating Cells from the Bottom Up. (2018) (182)
- Limiting Amounts of Centrosome Material Set Centrosome Size in C. elegans Embryos (2011) (181)
- Spindle Oscillations during Asymmetric Cell Division Require a Threshold Number of Active Cortical Force Generators (2006) (178)
- Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation (2018) (176)
- Growth, fluctuation and switching at microtubule plus ends (2009) (175)
- The Mammalian SPD-2 Ortholog Cep192 Regulates Centrosome Biogenesis (2008) (175)
- Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response (2010) (168)
- Aurora A activates D-TACC–Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules (2005) (168)
- Organelle Growth Control through Limiting Pools of Cytoplasmic Components (2012) (165)
- Motor proteins regulate force interactions between microtubules and microfilaments in the axon (2000) (165)
- CPAP promotes timely cilium disassembly to maintain neural progenitor pool (2016) (164)
- Regulating the Yeast Kinetochore by Ubiquitin-Dependent Degradation and Skp1p-Mediated Phosphorylation (1997) (160)
- Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles (2014) (159)
- Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p. (1999) (158)
- Codon adaptation–based control of protein expression in C. elegans (2011) (157)
- Phase separation provides a mechanism to reduce noise in cells (2019) (157)
- Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions (2020) (156)
- EB1 Recognizes the Nucleotide State of Tubulin in the Microtubule Lattice (2009) (156)
- Quantification of surface tension and internal pressure generated by single mitotic cells (2014) (153)
- Functional Repurposing Revealed by Comparing S. pombe and S. cerevisiae Genetic Interactions (2012) (152)
- Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans (2003) (151)
- Regulated assembly of a supramolecular centrosome scaffold in vitro (2015) (151)
- CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos (2006) (149)
- XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region (2011) (149)
- Katanin Disrupts the Microtubule Lattice and Increases Polymer Number in C. elegans Meiosis (2006) (148)
- A Bir1-Sli15 Complex Connects Centromeres to Microtubules and Is Required to Sense Kinetochore Tension (2006) (148)
- Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels (2013) (145)
- Site-Specific Cryo-focused Ion Beam Sample Preparation Guided by 3D Correlative Microscopy. (2016) (145)
- Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence (1991) (143)
- Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments (2018) (142)
- Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour (2011) (142)
- Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery. (2018) (142)
- XMAP215: a key component of the dynamic microtubule cytoskeleton. (2002) (141)
- Protein condensates as aging Maxwell fluids (2020) (139)
- Stu2p binds tubulin and undergoes an open-to-closed conformational change (2006) (139)
- A User’s Guide for Phase Separation Assays with Purified Proteins (2018) (138)
- Organization and Function of Non-dynamic Biomolecular Condensates. (2017) (137)
- Spatial organization of the cell cytoplasm by position-dependent phase separation. (2013) (137)
- Motor-Independent Targeting of CLASPs to Kinetochores by CENP-E Promotes Microtubule Turnover and Poleward Flux (2009) (136)
- Cyk-4 (2000) (132)
- Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end–binding microtubule destabilizer (2003) (132)
- APC15 mediates CDC20 autoubiquitylation by APC/CMCC and disassembly of the mitotic checkpoint complex (2012) (130)
- Cdk1-dependent mitotic enrichment of cortical myosin II promotes cell rounding against confinement (2015) (126)
- Structural Transitions at Microtubule Ends Correlate with Their Dynamic Properties in Xenopus Egg Extracts (2000) (125)
- One-step purification of assembly-competent tubulin from diverse eukaryotic sources (2012) (124)
- An introduction to Shi'i Islam: the history and doctrines of Twelver Shi'ism (1986) (124)
- Centrosome Size Sets Mitotic Spindle Length in Caenorhabditis elegans Embryos (2010) (123)
- Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding. (2007) (123)
- Tumor Necrosis Factor Induces Hyperphosphorylation of Kinesin Light Chain and Inhibits Kinesin-Mediated Transport of Mitochondria (2000) (118)
- Acto-myosin reorganization and PAR polarity in C. elegans (2007) (118)
- An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles. (2005) (118)
- The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos (2007) (116)
- Microtubule-motor activity of a yeast centromere-binding protein complex (1992) (113)
- Beyond stereospecificity: liquids and mesoscale organization of cytoplasm. (2011) (112)
- Stress Generation and Filament Turnover during Actin Ring Constriction (2007) (112)
- Suppression of Ostwald ripening in active emulsions. (2015) (112)
- Caenorhabditis elegans TAC-1 and ZYG-9 Form a Complex that Is Essential for Long Astral and Spindle Microtubules (2003) (111)
- Controlling compartmentalization by non-membrane-bound organelles (2018) (111)
- Correlative light and electron microscopy of early Caenorhabditis elegans embryos in mitosis. (2007) (110)
- XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules (2013) (110)
- Microtubule structure and dynamics. (1997) (109)
- Membrane Invaginations Reveal Cortical Sites that Pull on Mitotic Spindles in One-Cell C. elegans Embryos (2010) (108)
- GTP Binding Induces Filament Assembly of a Recombinant Septin (2002) (108)
- PAR proteins diffuse freely across the anterior–posterior boundary in polarized C. elegans embryos (2011) (107)
- Automated tracing of microtubules in electron tomograms of plastic embedded samples of Caenorhabditis elegans embryos. (2012) (106)
- A genomic toolkit to investigate kinesin and myosin motor function in cells (2013) (104)
- The role of nucleation in patterning microtubule networks. (1998) (103)
- RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. (2005) (102)
- A focused ion beam milling and lift-out approach for site-specific preparation of frozen-hydrated lamellas from multicellular organisms. (2015) (100)
- Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro (1994) (100)
- Rheology of the Active Cell Cortex in Mitosis. (2016) (99)
- Systematic Phosphorylation Analysis of Human Mitotic Protein Complexes (2011) (98)
- Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division (2009) (97)
- Natural product-inspired cascade synthesis yields modulators of centrosome integrity. (2012) (97)
- zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly. (2001) (97)
- Protein Dynamics in Complex DNA Lesions. (2018) (94)
- XMAP215 regulates microtubule dynamics through two distinct domains (2001) (93)
- The C. elegans RSA Complex Localizes Protein Phosphatase 2A to Centrosomes and Regulates Mitotic Spindle Assembly (2007) (91)
- LGL Can Partition the Cortex of One-Cell Caenorhabditis elegans Embryos into Two Domains (2010) (90)
- A role for microtubule dynamics in phagosome movement. (1998) (90)
- Structure and function of kinetochores in budding yeast. (1995) (90)
- Charles Babbage: Pioneer of the Computer (1984) (89)
- Principles of PAR polarity in Caenorhabditis elegans embryos (2013) (89)
- Structural changes at microtubule ends accompanying GTP hydrolysis: information from a slowly hydrolyzable analogue of GTP, guanylyl (alpha,beta)methylenediphosphonate. (1998) (88)
- Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes (2018) (84)
- Salt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical Traps. (2018) (84)
- Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production (2020) (84)
- Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy (2018) (80)
- Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. (1993) (80)
- Postmodernism and Islam: predicament and promise (1993) (77)
- FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy (2019) (77)
- Discovering Islam: making sense of Muslim history and society (1991) (76)
- Temperature Dependence of Cell Division Timing Accounts for a Shift in the Thermal Limits of C. elegans and C. briggsae. (2015) (76)
- Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores (2012) (75)
- LET-99, GOA-1/GPA-16, and GPR-1/2 Are Required for Aster-Positioned Cytokinesis (2007) (74)
- Cell cycle progression requires the CDC-48UFD−1/NPL−4 complex for efficient DNA replication (2008) (72)
- Microtubule-associated Protein-dependent Binding of Phagosomes to Microtubules (*) (1996) (72)
- Cyclin E–Cdk2 temporally regulates centrosome assembly and establishment of polarity in Caenorhabditis elegans embryos (2006) (71)
- Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease (2019) (70)
- Herman Hollerith: Forgotten Giant of Information Processing (1982) (68)
- Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo. (2008) (67)
- Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans. (2008) (65)
- The mbk‐2 kinase is required for inactivation of MEI‐1/katanin in the one‐cell Caenorhabditis elegans embryo (2003) (65)
- Purification of tubulin from porcine brain. (2011) (65)
- FRAP analysis of membrane-associated proteins: lateral diffusion and membrane-cytoplasmic exchange. (2010) (62)
- Mitotic cells contract actomyosin cortex and generate pressure to round against or escape epithelial confinement (2015) (62)
- Modulation of microtubule stability by kinetochores in vitro (1990) (60)
- A Dual Protein-mRNA Localization Screen Reveals Compartmentalized Translation and Widespread Co-translational RNA Targeting. (2020) (59)
- Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis (2014) (58)
- Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length (2016) (58)
- High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes (2011) (57)
- GTSE1 Is a Microtubule Plus-End Tracking Protein That Regulates EB1-Dependent Cell Migration (2012) (55)
- Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression. (2007) (54)
- Characterization of protein dynamics in asymmetric cell division by scanning fluorescence correlation spectroscopy. (2008) (54)
- Large-scale De Novo Prediction of Physical Protein-Protein Association* (2011) (54)
- Tracking mechanics and volume of globular cells with atomic force microscopy using a constant-height clamp (2012) (53)
- Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions (2022) (52)
- Cell structure and dynamics - Editorial overview (2005) (52)
- Cortical domains and the mechanisms of asymmetric cell division. (1996) (51)
- Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival (2014) (49)
- Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA. (1995) (48)
- Sequence-dependent surface condensation of a pioneer transcription factor on DNA (2020) (48)
- Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos (2010) (48)
- PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formation (2018) (46)
- Kinetochores distinguish GTP from GDP forms of the microtubule lattice (1997) (45)
- Correct spindle elongation at the metaphase/anaphase transition is an APC-dependent event in budding yeast (2001) (44)
- The crystal structure of sodium tetraborate (1967) (43)
- Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation (2016) (42)
- Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding (2017) (42)
- Generalized models for bond percolation transitions of associative polymers. (2020) (41)
- Timing and mechanism of the initial cue establishing handed left–right asymmetry in Caenorhabditis elegans embryos (2014) (40)
- Analysis of the distribution of the kinetochore protein Ndc10p in Saccharomyces cerevisiae using 3-D modeling of mitotic spindles (2003) (40)
- The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion (2018) (38)
- OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos. (2000) (37)
- Emergent Properties of the Metaphase Spindle. (2015) (37)
- Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis (2015) (37)
- Drops and fibers — how biomolecular condensates and cytoskeletal filaments influence each other (2020) (36)
- Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates (2021) (35)
- Motor proteins of the eukaryotic cytoskeleton. (1997) (35)
- Force probing cell shape changes to molecular resolution. (2011) (32)
- Moving out of Moscow's orbit: the outlook for Central Asia (1993) (32)
- The crystal structure of bismuth (2:1) borate, 2Bi2O3.B2O3 (1972) (31)
- NATIONALISM IN AFGHANISTAN (2002) (31)
- Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos (2010) (31)
- Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome (2014) (31)
- Amal and the Shi'a: struggle for the soul of Lebanon (1988) (30)
- Radical Islam: the Iranian Mojahedin (1990) (28)
- Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit (2017) (27)
- The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix (2014) (27)
- Extremist Shiites: the Ghulat sects (1990) (27)
- Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1 (2006) (26)
- Priority of discovery in the life sciences (2016) (25)
- A History of Biochemistry (2000) (25)
- The Mitotic Spindle in the One-Cell C. elegans Embryo Is Positioned with High Precision and Stability (2016) (25)
- A comparison of the ability of XMAP215 and tau to inhibit the microtubule destabilizing activity of XKCM1 (2005) (24)
- PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins* (2016) (24)
- Science and Reform: Selected Works of Charles Babbage (1989) (24)
- Crystal Structure of Ca2Na2(CO3)3 (Shortite). (1971) (24)
- Charles Babbage: Pioneer of the Modern Computer (1982) (23)
- A ubiquitin C-terminal hydrolase is required to maintain osmotic balance and execute actin-dependent processes in the early C. elegans embryo. (2002) (22)
- RNA gets in phase (2017) (22)
- Revolutions and rebellions in Afghanistan: anthropological perspectives (1985) (22)
- The first cell cycle of the Caenorhabditis elegans embryo: spatial and temporal control of an asymmetric cell division. (2011) (22)
- Soluble tubulin is significantly enriched at mitotic centrosomes (2019) (22)
- Charles Babbage: Pioneer of the Computer. (1985) (21)
- Inhibition of CPAP–tubulin interaction prevents proliferation of centrosome‐amplified cancer cells (2018) (21)
- The struggle for Afghanistan (1989) (21)
- Sestrin 2 Protein Regulates Platelet-derived Growth Factor Receptor β (Pdgfrβ) Expression by Modulating Proteasomal and Nrf2 Transcription Factor Functions* (2015) (21)
- Stem cells: the new “model organism” (2017) (20)
- Molecular biology: A liquid reservoir for silent chromatin (2017) (19)
- Spindle positioning during the asymmetric first cell division of Caenorhabditis elegans embryos. (2001) (19)
- Microtubule cytoskeleton: No longer an also Ran (1999) (19)
- Directed Growth of Biomimetic Microcompartments (2019) (19)
- The segmentation of microtubules in electron tomograms using Amira. (2014) (18)
- Afghanistan Under Soviet Domination, 1964-81 (1982) (18)
- Cell Polarity: The importance of being polar (1995) (18)
- Positioning of Particles in Active Droplets. (2018) (17)
- Spindle positioning and cell polarity (1992) (17)
- Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo (2020) (17)
- Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins. (2017) (16)
- Regulation of the direction of chromosome movement. (1991) (16)
- Quantitative phase microscopy enables precise and efficient determination of biomolecular condensate composition (2020) (16)
- Whither systems biology (2011) (15)
- Preparation of Tubulin from Porcine Brain (2006) (15)
- Role of chromosomes in assembly of meiotic and mitotic spindles. (1997) (14)
- Method: In vitro analysis of pericentriolar material assembly. (2015) (14)
- Cell division. (2006) (14)
- TransgeneOmics--A transgenic platform for protein localization based function exploration. (2016) (14)
- In vitro Reconstitution of a Membrane Switch Mechanism for the Polarity Protein LGL. (2016) (13)
- APC15 mediates CDC20 auto-ubiquitylation by APC/CMCC and MCC disassembly (2012) (13)
- Erratum: Spatial Organization of the Cell Cytoplasm by Position-Dependent Phase Separation [Phys. Rev. Lett. 111, 088101 (2013)] (2013) (13)
- Discriminative Semi-Markov Models for automated mitotic phase labelling (2012) (13)
- Centrosomes: Sic transit gloria centri (2000) (12)
- Glycine-Rich Peptides from FUS Have an Intrinsic Ability to Self-Assemble into Fibers and Networked Fibrils. (2021) (12)
- Resources for proteomics in mouse embryonic stem cells (2011) (12)
- Microtubule Dynamics: Kinetochores get a grip (1995) (12)
- Turkestan and pan‐Turkism revisited (1997) (12)
- kinetochores in budding yeast The conserved protein kinase Ipl 1 regulates microtubule binding to (1999) (12)
- Pioneer of the Computer (1982) (12)
- Charles Babbage–Pioneer of the Computer (1985) (12)
- HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA binding domain (2021) (11)
- Afghanistan under Soviet Domination, 1964-91 (1992) (11)
- The Afghan politics of exile (1987) (10)
- Afghanistan: politics, economics and society (1986) (9)
- HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain (2021) (9)
- An assay for the activity of microtubule-based motors on the kinetochores of isolated Chinese hamster ovary chromosomes. (1993) (9)
- Shi'ism, resistance and revolution (1987) (9)
- Two-photon fluorescence imaging and correlation analysis applied to protein dynamics in C. elegans embryo (2008) (8)
- Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation (2021) (8)
- Kinetochores on the move (1988) (8)
- Dynamic Time Warping for Automated Cell Cycle Labelling (2011) (8)
- In vitro reconstitution of endosome motility along microtubules. (2001) (8)
- The C. elegans Centrosome during Early Embryonic Development (2005) (8)
- A locus in Pristionchus pacificus that is responsible for the ability to give rise to fertile offspring at higher temperatures (2016) (6)
- The centrosome is a selective phase that nucleates microtubules by concentrating tubulin (2016) (6)
- Molecular basis of chromosome movement: Current Opinion in Structural Biology 1992, 2:275–279 (1992) (6)
- Quantitative theory for the diffusive dynamics of liquid condensates (2021) (6)
- Phosphatase PP2A and microtubule pulling forces disassemble centrosomes during mitotic exit (2017) (6)
- SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA (2022) (6)
- Afghanistan in perspective (1996) (5)
- The Glycolytic Protein Phosphofructokinase Dynamically Relocalizes into Subcellular Compartments with Liquid-like Properties in vivo (2019) (5)
- Cell Fate Determination: When is a determinant a determinant? (1994) (5)
- Erratum: BAC TransgeneOmics: A high-throughput method for exploration of protein function in mammals (Nature Methods (2008) vol. 5 (409-415)) (2008) (5)
- Encouraging innovation (2014) (4)
- On the Implications of Laterally Mobile Cortical Tension Elements for Cytokinesis (1987) (4)
- Functional analysis of kinetochore assembly in C. elegans (2001) (4)
- A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis (2012) (4)
- Political Change in Post-Soviet Central Asia (1994) (4)
- Characterization of RNA content in individual phase-separated coacervate microdroplets (2021) (4)
- MIACA – Minimum Information About a Cellular Assay: Standardized description of cell-based functional assay projects (2013) (4)
- Soluble tubulin is locally enriched at mitotic centrosomes in C. elegans (2019) (4)
- Temporal models for mitotic phase labelling (2014) (4)
- Computing. A dictionary of terms, concepts and ideas (1976) (4)
- C11ORF24 Is a Novel Type I Membrane Protein That Cycles between the Golgi Apparatus and the Plasma Membrane in Rab6-Positive Vesicles (2013) (3)
- Publisher Correction: Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding (2019) (3)
- Products of the Parkinson’s-disease related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival (2014) (3)
- Atomic Force Microscopy to Study Mechanics of Living Mitotic Mammalian Cells (2011) (3)
- ESI mutagenesis: A one-step method for introducing point mutations into bacterial artificial chromosome transgenes (2019) (3)
- Biomolecular condensate phase diagrams with a combinatorial microdroplet platform. (2022) (3)
- Local thermodynamics governs the formation and dissolution of protein condensates in living cells (2021) (3)
- The Saur Revolution (1984) (3)
- Priority of discovery in the life (2016) (3)
- Mitotic phase based detection of chromosome segregation errors in embryonic stem cells (2013) (3)
- Erratum: Salt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical Traps [Phys. Rev. Lett. 121, 258101 (2018)]. (2020) (2)
- A conserved role of Parkinson-associated DJ-1 metabolites in sperm motility, mitosis, and embryonic development (2021) (2)
- Central Asian republics: Independence and after (1997) (2)
- The political language of Islam and Islam and revolution in the Middle East (1988) (2)
- Afghanistan's unpopular revolution (1979) (2)
- A State of Nature (1984) (2)
- Funding Innovative Science (2013) (2)
- PLK4 is a microtubule-associated protein that self assembles promoting de novo MTOC formation (2018) (2)
- The Land and the People in History (1984) (2)
- A Bleeding Wound (1992) (2)
- High-Voltage Electron Tomography of the Centrosome in Caenorhabditis elegans (2002) (2)
- High Resolution and Multidimensional Protein Condensate Phase Diagrams with a Combinatorial Microdroplet Platform (2022) (2)
- Afghan intelligentsia 1978-81: For four traumatic years all independent thinkers have been under attack. (1982) (2)
- ESI mutagenesis: a one-step method for introducing mutations into bacterial artificial chromosomes (2020) (2)
- Charles Babbage: Science and reform (2002) (2)
- Afghanistan and Central Asia (1997) (2)
- Charles Babbage, 1791-1871, Philosoph, Mathematiker, Computerpionier (1987) (2)
- No great change in human rights (1989) (2)
- Crystal Structure of Ca 2 Na 2 ( C 0 3 ) 3 ( Shortite ) (2)
- Boveri revisited (2005) (2)
- Molecular mechanisms of stress-induced reactivation in mumps virus condensates (2022) (2)
- Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK / XKCM 1 (2006) (1)
- Pakistan and the commonwealth: An expanding organization? (1988) (1)
- Bangladesh under martial law (1983) (1)
- Ancestral figure of computing (1978) (1)
- The war in Afghanistan: an account and analysis of the country, its people, Soviet intervention and the resistance (1989) (1)
- ASCB Keith Porter Lecture. (2020) (1)
- Polo kinase phosphorylation determines C. elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation (2016) (1)
- Molecular Grammar Governing Phase Behavior of Intrinsically Disordered Proteins with Prion-like Domains (2018) (1)
- Opposing Activities of Hydrostatic Pressure and Actomyosin Contraction Drive Mitotic Cell Rounding (2010) (1)
- Red flag over Afghanistan: the communist coup, the Soviet invasion, and the consequences (1985) (1)
- XMAP215 and EB1 act in Synergy to Promote Microtubule Growth (2013) (1)
- Book Reviews: Arts of the Islamic world (1996) (1)
- ‘Positive Non-alignment’ (1984) (1)
- Ultrastructural Localization of Antigens in the Mitotic Spindle of Budding Yeast Using High Presure Freezing and Freeze Substitution (2000) (1)
- Regulation of yeast Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p (1998) (1)
- A localization screen reveals translation factories and widespread co-translational RNA targeting (2020) (1)
- Reading Afghan public opinion: Voices from the camps (1990) (1)
- Mitotic spindle oscillations (2005) (1)
- Adaptation to environmental temperature in divergent clades of the nematode Pristionchus pacificus (2022) (1)
- Iran's press — freedom within limits (1990) (1)
- In Memoriam: Professor Sayed Bahauddin Majrooh (1988) (1)
- Different low-complexity regions of SFPQ play distinct roles in the formation of biomolecular condensates (2022) (1)
- Armenian tragedy: an eye-witness account of human conflict and natural disaster in Armenia and Azerbaijan (1990) (1)
- Afghan/Pakistan border disputes (1980) (1)
- Phase Transitions in Cells − − Beyond Oil and Water (2012) (1)
- Why publish single observations? Because Science Matters. (2016) (0)
- The path to condensates—19th Wiley Prize in Biomedical Sciences laureates share their discovery stories (2022) (0)
- Dissecting the mechanisms of liquid to solid phase transition associated with neurodegenerative diseases (2016) (0)
- The Numb protein, which is asymmetrically distributed during certain cell divisions in the nervous system of Drosophila, may have a role in determining the developmental fates of the daughter cells. (1994) (0)
- CD-CODE: crowdsourcing condensate database and encyclopedia. (2023) (0)
- A conserved and tunable mechanism for the temperature-controlled condensation of the translation factor Ded1p (2022) (0)
- Sestrin 2 Regulates PDGF Receptor beta (PDGFR β ) Expression by Modulating Proteasomal and Nrf2 Transcription Factor Functions* (2015) (0)
- XMAP215 is a Processive Microtubule Polymerase Please share how this access benefits you. Your story matters (2008) (0)
- An antibody validation scheme for immunofluorescence using gene tagging (2016) (0)
- Toward Exploring the 3D Supramolecular Architecture of Centrosomes In-Situ (2013) (0)
- The Caenorhabditis elegans Centrosomal Protein SPD-2 Is Required for both Pericentriolar Material Recruitment and Centriole Duplication (2006) (0)
- Liquid-like protein condensates are glassy (2019) (0)
- Science Journals — AAAS (2020) (0)
- Actin Ring Constriction (2013) (0)
- 3K1334 A single-cell RNAi screen for regulators of mitotic cell mechanics identifies diseases-associated genes(Cell biology 4,The 49th Annual Meeting of the Biophysical Society of Japan) (2011) (0)
- The mechanical properties of phase separated protein droplets (2016) (0)
- Automated Cell Volume Estimation in Time-Lapse Microscopy Images (2014) (0)
- C . elegans genome-wide ChIP-seq in Diverse transcription factor binding features revealed by Material Supplemental (2011) (0)
- Principles of Systems Biology, No. 11. (2016) (0)
- Quantitative droplet FRAP based on physical principles (2020) (0)
- Suppression of Ostwald Ripening by Chemical Reactions (2015) (0)
- SILAC based quantitative proteomics to determine specific protein-protein and protein-DNA interactions (2008) (0)
- Functional proteomics of the human centrosome (2010) (0)
- Actin(g) on phase separation (2020) (0)
- Role of cortical rigidity in spindle positioning in C. elegans (2009) (0)
- Q & A Tony Hyman (2011) (0)
- The mechanical properties of p-granule components (2015) (0)
- C. elegans uses Liquid-Liquid Demixing for the Assembly of Non-Membrane-Bound Compartments CHRISTOPH A. WEBER, FRANK (2015) (0)
- Cytoplasmic Volume Modulates Spindle Size During Embryogenesis (2013) (0)
- 3D reconstruction of cellular microtubule networks using time- resolved live cell imaging and serial electron tomography (2015) (0)
- Cell division. Kinetochores on the move. (1988) (0)
- Analysis of microtubule binding by budding yeast kinetochores in vitro (2001) (0)
- metabolism of dihomo-?-linolenic acid to bronchoactive products in the canine lung (1983) (0)
- The multiple facets of RNA in development and disease February 7-9 2018 (2018) (0)
- Abstract GS3-10: Partitioning of cancer therapeutics in nuclear condensates (2021) (0)
- Polo-like kinase phosphorylation determines <italic>Caenorhabditis</italic> <italic>elegans</italic> centrosome size and density by biasing SPD-5 toward an assembly-competent conformation (2016) (0)
- Complementary proteomics methods identify novel components localizing asymmetrically to centrosomes (2011) (0)
- The Forces that Center the Mitotic Spindle (2012) (0)
- An mRNA competition mechanism regulates localized phase separation of liquid- like P granules in C-elegans embryo. (2016) (0)
- High-Voltage Electron Tomography of the Early C. elegans Mitotic Spindle (2003) (0)
- How Do Cells Form Compartments and How Is This Related to the Onset of Neurodegenerative Diseases (2017) (0)
- CommentarySpindle Positioning by Cortical Pulling Forces (2005) (0)
- Protein Interactions Control Dynamics of Liquid Compartments (2018) (0)
- Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing (2021) (0)
- Could dividing active droplets provide a model for protocells (2017) (0)
- Eukaryotic cell division genes and their use in diagnostics as well as in the treatment of proliferative diseases (2001) (0)
- Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding (2017) (0)
- Coacervates and Protein-Rich Droplets : Volume and Area Grow Simultaneously (2019) (0)
- Parallel adaptation to higher temperatures in divergent clades of the nematode Pristionchus pacificus (2016) (0)
- Eukaryotic genes for modulating cell cycle progression (2004) (0)
- Pattern-Forming System Polarization of PAR Proteins by Advective Triggering of a (2014) (0)
- Modulation oftheDynamic Instability ofTubulin Assembly bytheMicrotubule-Asso (1992) (0)
- Force Probing the Molecular Mechanics of Cell Rounding (2010) (0)
- Partitioning of cancer therapeutics in nuclear condensates. (2021) (0)
- Afghanistan: One death more or less (2007) (0)
- Society and Economy (2021) (0)
- The politics of Islamic revivalism: diversity and unity and Islamic fundamentalism (1988) (0)
- Author response: HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain (2021) (0)
- Ancestral voices of Iran (1982) (0)
- Musaddiq and the struggle for power in Iran (1992) (0)
- EMBO Gold Medal Review 2003 Boveri revisited (2005) (0)
- Islam and politics (1985) (0)
- Book Review: Henry S. Bradsher, Afghanistan and the Soviet Union (Durham NC: Duke University Press, 1985, 384pp., £12.95 pbk.). Edward G. Girardet, Afghanistan: The Soviet War (London: Croom Helm, 1985, 259pp., £17.95 pbk.) (1986) (0)
- Taboo themes: Drugs and pollution in Central Asia (1989) (0)
- Afghan Foreign Relations (1984) (0)
- Afghanistan: War and reconciliation? (1992) (0)
- Gold Medal Review 2003 Boveri revisited (2005) (0)
- The forces at work in militant Islam (1980) (0)
- The conflict of tribe and state in Iran and Afghanistan (1985) (0)
- Return of the native (1992) (0)
- Samurai Sword Sets Spindle Size (2011) (0)
- The New Democracy and its Limitations (1984) (0)
- The grim reality of Afghan exiles (1990) (0)
- The computer in design (1973) (0)
- Laura Otis.Networking: Communicating with Bodies and Machines in the Nineteenth Century. (Studies in Literature and Science.) 312 pp., figs., index. Ann Arbor: University of Michigan Press, 2002. $49.50 (cloth). (2002) (0)
- Afghanistan in crisis: A review article (1982) (0)
- Reforms from Above and Repressions (1984) (0)
- Structural and Molecular Determinants of Dynamics in P Granules of C. Elegans (2021) (0)
- Condensate-mediated reactivation of mumps virus infection under stress (2021) (0)
- Pakistan: Towards a Modern Muslim State? (2019) (0)
- Author response: Priority of discovery in the life sciences (2016) (0)
- TOG domain structure from C.elegans Zyg9 (2007) (0)
- Mitotic Cell Shape - RNA Interference Screening for Genes Involved in Mechanics using Atomic Force Microscopy (2014) (0)
- Afghanistan: A suitable case for intervention (2007) (0)
- One death more or less (1994) (0)
- Jihad and the Superpower Proxy War (1992) (0)
- Historical Dictionary of Afghanistan (1999) (0)
- Afghan Centres of Opposition (1984) (0)
- Anthony Hyman: from unlikely scientist to Royal Society Fellow. Interview by Ruth Williams. (2007) (0)
- Charles Babbage—computer pioneer (1991) (0)
- Ada, countess of lovelace: Byron's legitimate daughter: By Doris Langley Moore. New York (Harper & Row). 1977. $25.00 (1978) (0)
- The fall of Afghanistan: an insider's account, War in Afghanistan and Among the Afghans (1988) (0)
- Disintegrating Army v. Divided Opposition (1984) (0)
- Barnett R. Rubin: The fragmentation of Afghanistan: state formation and collapse in the international system . xix, 378 pp. New Haven and London: Yale University Press, 1995. £24. (1996) (0)
- News Review (2003) (0)
- Between Marx and Muhammad: the changing face of Central Asia (1994) (0)
- Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation (2018) (0)
- Waiting for Allah: Pakistan's struggle for democracy (1992) (0)
- A suitable case for intervention (1994) (0)
- Supplemental Data Identification and Characterization of Factors Required for Microtubule Growth and Nucleation in the Early C. elegans Embryo (2001) (0)
- TransgeneOmics: a platform for systems wide protein function analysis in metazoans (2010) (0)
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