Anthony Czarnik
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American biochemist
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Anthony Czarnikbiology Degrees
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Anthony Czarnik's Degrees
- PhD Chemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Anthony Czarnik Influential?
(Suggest an Edit or Addition)According to Wikipedia, Anthony W. Czarnik is an American chemist and inventor. He is best known for pioneering studies in the field of fluorescent chemosensorss and co-founding Illumina, Inc., a biotechnology company in San Diego. Czarnik was also the founding editor of ACS Combinatorial Science. He currently serves as an adjunct visiting professor at the University of Nevada, Reno.
Anthony Czarnik's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A LONG-WAVELENGTH FLUORESCENT CHEMODOSIMETER SELECTIVE FOR CU(II) ION IN WATER (1997) (837)
- Fluorescent chemosensors for ion and molecule recognition (1993) (786)
- Chemical Communication in Water Using Fluorescent Chemosensors (1994) (732)
- Fluorescent chemosensors of carbohydrates. A means of chemically communicating the binding of polyols in water based on chelation-enhanced quenching (1992) (411)
- Chemosensors of ion and molecule recognition (1997) (354)
- Real-Time Assay of Inorganic Pyrophosphatase Using a High-Affinity Chelation-Enhanced Fluorescence Chemosensor (1994) (271)
- Fluorimetric chemodosimetry. Mercury(II) and silver(I) indication in water via enhanced fluorescence signaling (1992) (270)
- Chelation-enhanced fluorescence of anthrylazamacrocycle conjugate probes in aqueous solution (1990) (231)
- Desperately seeking sensors. (1995) (187)
- Chelation enhanced fluorescence detection of non-metal ions (1989) (162)
- Chelation enhanced fluorescence in 9,10-bis[[(2-(dimethylamino)ethyl)methylamino]methyl]anthracene (1988) (151)
- Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism. (1998) (136)
- A sense for landmines (1998) (136)
- Inhibitors of protein-RNA complexation that target the RNA: specific recognition of human immunodeficiency virus type 1 TAR RNA by small organic molecules. (1998) (131)
- A fluorescent chemosensor signalling only Hg(II) and Cu(II) in water (1997) (125)
- Discovery of selective, small-molecule inhibitors of RNA complexes--I. The Tat protein/TAR RNA complexes required for HIV-1 transcription. (1997) (123)
- A practical guide to combinatorial chemistry (1997) (121)
- INHIBITION OF AN HIV-1 TAT-DERIVED PEPTIDE BINDING TO TAR RNA BY AMINOGLYCOSIDE ANTIBIOTICS (1995) (116)
- Ribonucleoside membrane transport by a new class of synthetic carrier (1993) (105)
- Functional group convergency in a binuclear dephosphorylation reagent (1993) (104)
- Transaminations by pyridoxamine selectively attached at C-3 in .beta.-cyclodextrin (1983) (94)
- Combinatorial Organic Synthesis Using Parke-Davis's DIVERSOMER Method (1996) (92)
- Mimics of transaminase enzymes (1986) (91)
- Encoding methods for combinatorial chemistry. (1997) (90)
- Chelatoselective fluorescence perturbation in anthrylazamacrocycle conjugate probes. Electrophilic aromatic cadmiation (1990) (88)
- Combinatorial Chemistry: Synthesis and Application (2003) (72)
- .alpha.-Amino acid chelative complexation by an arylboronic acid (1993) (68)
- Synthesis and reactivity of cobalt(III) complexes bearing primary- and secondary-side cyclodextrin binding sites. A tale of two CD's (1988) (65)
- Structural effects controlling the rate of the retro-Diels-Alder reaction in anthracene cycloadducts (1989) (65)
- Synthesis and some reactions of hexaazatriphenylenehexanitrile, a hydrogen-free polyfunctional heterocycle with D3h symmetry (1986) (59)
- A general fluorescence assay for enzyme catalyzed polyanion hydrolysis based on template directed excimer formation. Application to heparin and polyglutamate (1990) (52)
- Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs (2015) (48)
- Improved synthesis of 1,4,5,8,9,12-hexaazatriphenylenehexacarboxylic acid (1994) (46)
- Fluorescent chemosensing of catechol and catecholamines in water. (1993) (45)
- Cyclodextrin-mediated chiral sulfoxidations (1984) (44)
- Chelation‐enhanced fluorescence chemosensing of Pb(II), an inherently quenching metal ion (1996) (41)
- Syntheses of 9,10-disubstituted anthracenes derived from 9,10-dilithioanthracene (1988) (41)
- New reagents for the syntheses of fluorescent chemosensors. Anthrylogous ethylene dibromides (1993) (40)
- A General Method for the Synthesis of Cyclodextrinyl Aldehydes and Carboxylic Acids (1995) (40)
- Synthesis and characterization of a reactive binuclear co(III) complex. Cooperative promotion of phosphodiester hydrolysis (1990) (35)
- .pi.-Complexation in the Solid State Induced by Intermolecular Hydrogen Bonding (1994) (33)
- Intramolecular general base-acid catalysis in transaminations catalyzed by pyridoxamine enzyme analogs (1983) (30)
- Peer Reviewed: Combinatorial Chemistry (1998) (30)
- Selective transport of ribonucleosides through a liquid membrane (1989) (29)
- Mimics of Tryptophan Synthetase and of Biochemical Dehydroalanine Formation (1985) (29)
- Metal ion catalyzed reactions of acrylonitrile, acrylamide, and ethyl acrylate by way of their Diels-Alder cycloadducts (1987) (29)
- Discovery of selective, small-molecule inhibitors of RNA complexes--II. Self-splicing group I intron ribozyme. (1997) (26)
- solid‐phase organic synthesis (2001) (26)
- Encoding strategies in combinatorial chemistry. (1997) (25)
- Supramolecular Chemistry, Fluorescence, and Sensing (1993) (23)
- DIVERSOMERTM technology: Solid phase synthesis, automation, and integration for the generation of chemical diversity (1994) (23)
- Structural requirements for efficient photoinduced electron transfer (PET) quenching in 9-aminoalkylanthracenes (1993) (22)
- Kinetic Comparison of Amide Formation on Various Cross-Linked Polystyrene Resins (1999) (21)
- Facile preparation of the β-cyclodextrinyl aldehyde (1994) (19)
- Inhibition of self-splicing group I intron RNA: high-throughput screening assays. (1996) (19)
- Polystyrene grafted fluoropolymer microtubes: New supports for solid-phase organic synthesis with useful performance at high temperature (1999) (17)
- A combinatorial synthesis of tyrphostins via the "directed sorting" method. (1998) (16)
- Web alert Combinatorial chemistry (1997) (16)
- Preassociating .alpha.-nucleophiles (1992) (15)
- Reversal of electronic substituent effects in the retro-Diels-Alder reaction. A charge neutral analog of oxyanion-accelerated cycloreversion (1986) (15)
- Merrifield MicroTubeTM reactors for solid phase synthesis (1998) (14)
- A metal-ion-insensitive polyanion chemosensor (1993) (14)
- Rapid transacylations of activated ester substrates bound to the primary side β-cyclodextrin-cyclen conjugate and its M2+ complexes (1991) (14)
- An assay to determine the kinetics of RNA cleavage. (1985) (13)
- Diene-substituent effects on the rate of the retro-Diels-Alder reaction. Cycloreversion reactivity varying over a range of 105 (1988) (13)
- Nitrosations in Anhydrous Trifluoroacetic Acid Media: A Modification for Insoluble or Deactivated Amine and Amide Precursors (1988) (13)
- Integrated Drug Discovery Technologies (2002) (13)
- Synthesis, stereochemistry, intramolecular cyclization, and rates of hydrolysis of adenosine 2',3'-acetals. (1987) (13)
- Optimization of Solid-Phase Combinatorial Synthesis (2001) (12)
- Chelation-enhanced fluorescence in 9,10-bis(TMEDA)anthracene (1988) (12)
- PREASSOCIATING ALPHA -NUCLEOPHILES BASED ON BETA -CYCLODEXTRIN. THEIR SYNTHESIS AND REACTIVITY (1995) (12)
- Effects of cyclonucleoside formation on the rates of glycosidic hydrolyses in purine ribonucleosides (1987) (12)
- Fluorescent Chemosensors of Ion and Molecule Recognition: Recent Applications to Pyrophosphate and to Dopamine Sensing (1994) (12)
- METAL ION-CATALYZED HYDROLYSIS OF ACRYLATE ESTERS AND AMIDES BY WAY OF THEIR CONJUGATE ADDITION ADDUCTS (1995) (12)
- Chemical communication of enzymatic ATP hydrolysis using a fluorescent chemosensor (1993) (11)
- Foreshortened nucleotide analogs as potential base-pairing complements for lin-benzoadenosine (1982) (11)
- Copper-catalyzed redox deacylation of isomeric N- and O-benzoylhydroxylamines (1992) (10)
- Combinatorial Organic Synthesis Using Parke‐Davis′s DIVERSOMER Method (1996) (10)
- Hexadecarboxylative Synthesis of Hexaazatriphenylene (1988) (10)
- Unequivocal assignment of the skeletal structure of the guanine-glyoxal adduct (1980) (10)
- Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity (2021) (9)
- Syntheses of some hexacarboxylic acid derivatives of hexaazatriphenylene (1988) (9)
- Synthesis and transacylating activity of isomeric Co(III)‐cyclodextrin artificial metalloenzymes (1992) (9)
- Fluorescent Signal Transduction in Molecular Sensors and Dosimeters (1993) (9)
- Retrograde Diels–Alder Reactions (1991) (9)
- Models for nucleoside glycosylase enzymes. Evidence that the hydrolysis of .beta.-D-ribofuranosides requires a backside preassociation nucleophile (1990) (8)
- Hexadeoxycycloheptaamylose-pyridoxamine, an artificial transaminase with a "deeper" binding pocket. (1984) (8)
- CU(II) Catalyzed Hydrolysis of an Unactivated Ester Based on Reversible Conjugate Addition (1989) (8)
- Solid-phase synthesis of alkyl aryl ethers via the Ullmann condensation. (2002) (7)
- Copper(II)-catalysed hydrolysis of an unactivated amide. Application of the groves' rule to the hydrolysis of acrylamide (1990) (7)
- 2.12 – How and Why to Apply the Latest Technology* (2007) (7)
- Deuterium-Enabled Chiral Switching (DECS) Yields Chirally Pure Drugs from Chemically Interconverting Racemates (2020) (7)
- Ni(II)-promoted conversion of acrylamide to ethyl acrylate using the diels-alder reaction. (1984) (7)
- The impact of polystyrene resins in solid-phase organic synthesis (1996) (7)
- Synthesis and transacylating reactivity of β-cyclodextrin ethylenediamines (1994) (7)
- Rapid intermolecular electron transfer specific to the zwitterionic form of N-(9-(10-hydroxyanthryl)piperidine (HAP) (1991) (6)
- .alpha.-Amino acid chelative complexation by an arylboronic acid. [Erratum to document cited in CA119(17):181171a] (1994) (5)
- Synthesis of β-cyclodextrin oximes (1994) (5)
- Chemosensors: Synthetic Receptors in Analytical Sensing Applications (2007) (5)
- Aqueous solubilization of a synthetic charge-transfer receptor via cycloamylose inclusion (1993) (4)
- CONFIRMATION OF THE STRUCTURE OF THE GUANINE-METHYLMALONDIALDEHYDE REACTION PRODUCT BY UNEQUIVOCAL SYNTHESIS (1981) (4)
- TRANSAMINATIONS BY PYRIDOXAMINE SELECTIVELY ATTACHED AT C‐3 IN β‐CYCLODEXTRIN (1983) (4)
- A Cyclitively Cleavable Linker for Alcohols: Linker Preparation and Cleavage Conditions (1999) (3)
- Hydrogen bonding effects on the reactivity of a preassociating α-nucleophile. the secondary-side βCD hydroxylamine (1992) (3)
- Preparatively Useful Oxidation Reactions of Hexamethylhexaazatriphenylene (1995) (3)
- Improved Synthesis of 1,4,5,8,9,12-Hexaazatriphenylenehexacarboxylic Acid. (1994) (2)
- Intramolecular carboxylate catalysis in the depurination of a 7-methylguanosine derivative. (1993) (2)
- On the function of ionized carboxylate residues at the active sites of glycosyl transferase enzymes (1987) (2)
- Experimental support for Asp-52's importance in lysozyme using a carbohydrate-based enzyme model: acetal hydrolysis catalyzed by a stereoelectronically correct carboxylate group (1988) (2)
- Cu(II)-promoted hydrolysis of N-benzoyliminodiacetic acid (1992) (2)
- Metal Ion Catalyzed Reactions of Acrylonitrile, Acrylamide, and Ethyl Acrylate by Way of Their Diels-Alder Cycloadducts. (1987) (2)
- Synthesis and Some Reactions of Hexaazatriphenylenehexacarbonitrile, a Hydrogen-Free Polyfunctional Heterocycle with D3h Symmetry. (1987) (2)
- Cu(II)-catalysis in the reduction of , -dibenzoylhydroxylamine by a tertiary amine (1993) (2)
- Fluorimetric metal ion sensing usingN-methyl-9-anthrylhydroxamic acid (1992) (2)
- Combinatorial synthesis of deuterium-enriched atorvastatin (2016) (2)
- Tubes and Cubes, Chips and Tips: Tools for Solid‐Phase Organic Synthesis (2000) (1)
- Acceleration of the Retro-Diels-Alder Reactions of Anthracene Cycloadducts by Distal Siloxy Substituents (1997) (1)
- Synthesis and transacylating reactivity of beta-cyclodextrin ethylenediamines. (1994) (1)
- Hexadecarboxylative Synthesis of Hexaazatriphenylene. (1988) (1)
- New Reagents for the Syntheses of Fluorescent Chemosensors. Anthrylogous Ethylene Dibromides. (1994) (1)
- Synthesis and thermogravimetric analyses of trisimides and polyimides derived from hexaazatriphenylene (1989) (1)
- Combinatorial chemistry (1998) (1)
- Parallel Organic Synthesis Using Parke-Davis′ Diversomer Method (1998) (1)
- A Fluorescent Chemosensor with Selectivity for Hg(II) (1997) (1)
- Fluorescent Chemosensors for Cations, Anions, and Neutral Analytes (2002) (1)
- What's in it for analytical chemists? (1998) (1)
- Hexaazatriphenylenehexacarboxamide Solvate Exhibiting p-Complexation in the Solid State (1996) (1)
- Chemical Communication in Water Using Fluorescent Chemosensors. (1995) (1)
- Diene-Substituent Effects on the Rate of the Retro-Diels-Alder Reaction. Cycloreversion Reactivity Varying over a Range of Five Powers of Ten. (1988) (0)
- Faculty Opinions recommendation of Detection of DNA hybridization using the near-infrared band-gap fluorescence of single-walled carbon nanotubes. (2006) (0)
- Precomplexation and Activation of Carboxylate and Phosphate Esters (1992) (0)
- Syntheses of 9,10-Disubstituted Anthracenes Derived from 9,10-Dilithioanthracene. (1988) (0)
- Fluorescent chemosensors that signal carbohydrates in aqueous solution: a novel mechanism for signal transduction is required and found (1993) (0)
- Molecular recognition in drug discovery. A special issue based on the 36th Annual Buffalo Medicinal Chemistry Symposium (1996) (0)
- Combinatorial synthesis of deuterium-enriched (S)-oxybutynin (2016) (0)
- Faculty Opinions recommendation of Synthesis and properties of a new fluorescent bicyclic 4-N-carbamoyldeoxycytidine derivative. (2006) (0)
- Oligonucleotide Libraries as a Source of Molecular Diversity (1999) (0)
- Faculty Opinions recommendation of Facile quantification of enantiomeric excess and concentration with indicator-displacement assays: an example in the analyses of alpha-hydroxyacids. (2004) (0)
- Chemical Studies on Nucleic Acid Analogues (1981) (0)
- Combinatorial synthesis of deuterium-enriched (S)-oxybutynin (2016) (0)
- Syntheses of Some Hexacarboxylic Acid Derivatives of Hexaazatriphenylene. (1989) (0)
- Nitrosation in Anhydrous Trifluoroacetic Acid Media: A Modification for Insoluble or Deactivated Amine and Amide Precursors. (1988) (0)
- The Chemistry of Hexaazatriphenylene Hexanitrile, a Polyfunctional Heterocycle with Potential Utility in the Formulation of Thermostable Polymers (1989) (0)
- Faculty Opinions recommendation of Selection and amplification of hosts from dynamic combinatorial libraries of macrocyclic disulfides. (2002) (0)
- Méthodes et compositions de criblage intrabille (2000) (0)
- Reversal of Electronic Substituent Effects in the Retro-Diels-Alder Reaction. A Charge Neutral Analogue of Oxyanion-Accelerated Cycloreversion. (1987) (0)
- Encoding Methods for Combinatorial Chemistry (1997) (0)
- Faculty Opinions recommendation of Control of protein phosphorylation with a genetically encoded photocaged amino acid. (2007) (0)
- Tubes and Cubes, Chips and Tips: Tools for Solid-Phase Organic Synthesis (2001) (0)
- Mimics of Transaminase Enzymes. (1986) (0)
- Faculty Opinions recommendation of Naked-eye detection of fluoride ion in water: a remarkably selective easy-to-prepare test paper. (2006) (0)
- Structure of a model compound for the lysozyme–substrate complex (1990) (0)
- Automated Synthesis and Combinatorial Chemistry (1996) (0)
- Faculty Opinions recommendation of Switching the recognition preference of rhodamine B spirolactam by replacing one atom: design of rhodamine B thiohydrazide for recognition of Hg(II) in aqueous solution. (2006) (0)
- Parallel Organic Synthesis Using Parke—Davis Diversomer Technology (2010) (0)
- Faculty Opinions recommendation of Fluorescence sensing of ionic analytes in water: from transition metal ions to vitamin B13. (2002) (0)
- Combinatorial synthesis of deuterium-enriched atorvastatin (2016) (0)
- Cu(II)-Catalyzed Hydrolysis of an Unactivated Ester Based on Reversible Conjugate Addition. (1990) (0)
- Faculty Opinions recommendation of Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. (2007) (0)
- Rapid Intermolecular Electron Transfer Specific to the Zwitterionic Form of N‐(9‐(10‐Hydroxyanthryl))piperidine (HAP). (1991) (0)
- NICKEL(II)-PROMOTED CONVERSION OF ACRYLAMIDE TO ETHYL ACRYLATE USING THE DIELS-ALDER REACTION (1985) (0)
- Structural Effects Controlling the Rate of the Retro-Diels-Alder Reaction in Anthracene Cycloadducts. (1989) (0)
- Correction to Synthesis and Some Reactions of Hexaazatriphenylene Hexanitrile, a Hydrogen-Free Polyfunctional Heterocycle with D3h Symmetry (2021) (0)
- Screening methods porous microspheres and compositions (2000) (0)
- Synthesis, Stereochemistry, Intramolecular Cyclization, and Rates of Hydrolysis of Adenosine 2′,3′-Acetals. (1988) (0)
- United States Patent ( 19 ) Czarnik et al . ( 54 ) HEXAAZATRIPHENYLENE HEXANITRILE AND ITS DERVATIVES AND THEIR PREPARATIONS (2017) (0)
- Decoding matrix-like-arranged sensors by microparticles (1999) (0)
- LIBRARY SYNTHESIS TECHNIQUES (1998) (0)
- Effects of Cyclonucleoside Formation on the Rates of Glycosidic Hydrolyses in Purine Ribonucleosides. (1987) (0)
- Chelation-enhanced fluorescence detection of metal and nonmetal ions in aqueous solution (1992) (0)
- Faculty Opinions recommendation of Measuring picomolar intracellular exchangeable zinc in PC-12 cells using a ratiometric fluorescence biosensor. (2006) (0)
- Copper‐Catalyzed Redox Deacylation of Isomeric N‐ and O‐ Benzoylhydroxylamines. (2010) (0)
- Faculty Opinions recommendation of Rainbow beads: a color coding method to facilitate high-throughput screening and optimization of one-bead one-compound combinatorial libraries. (2008) (0)
- Decoding matrix sensors with microspheres (2000) (0)
- Faculty Opinions recommendation of The discovery of acylated beta-amino acids as potent and orally bioavailable VLA-4 antagonists. (2002) (0)
- Faculty Opinions recommendation of Interior surface modification of bacteriophage MS2. (2004) (0)
- Synthetic Catalysts that Hydrolyze Phosphate and Carboxylate Esters (1992) (0)
- Cu(II)‐Promoted Hydrolysis of N‐Benzoyliminodiacetic Acid. (1993) (0)
- Synthesis and hydrolysis kinetics of 1-O-[p-(N,N,N-trimethylammonio)phenyl]-.beta.-D-ribofuranoside (1993) (0)
- Faculty Opinions recommendation of Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. (2006) (0)
- This issue introduces a set of ideas called "Distributed Drug Discovery (D(3))". (2009) (0)
- Figure 1 Impact of HTOS on new drug development. (2002) (0)
- Solid‐Phase Synthesis of Ureas on Microtubes (2001) (0)
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