Antonio Sica

Q: What Schools Are Affiliated With Antonio Sica

Antonio Sica is affiliated with the following schools: University of Milan, University of Eastern Piedmont, Stanford University, University of Brescia

Antonio Sica's AcademicInfluence.com Rankings

Antonio Sica

Physics

#4390

World Rank

#6041

Historical Rank

physics Degrees

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Physics

Antonio Sica's Degrees

PhD Physics University of Milan
Masters Physics University of Milan
Bachelors Physics University of Milan

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Antonio Sica's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cancer-related inflammation (2008) (9454)
The chemokine system in diverse forms of macrophage activation and polarization. (2004) (5622)
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. (2002) (4728)
Macrophage plasticity and polarization: in vivo veritas. (2012) (4585)
Macrophage activation and polarization: nomenclature and experimental guidelines. (2014) (4128)
Macrophage activation and polarization. (2008) (2890)
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. (2009) (2522)
Macrophage plasticity and polarization in tissue repair and remodelling (2013) (1842)
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards (2016) (1817)
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. (2006) (1396)
Macrophages, innate immunity and cancer: balance, tolerance, and diversity. (2010) (1339)
Altered macrophage differentiation and immune dysfunction in tumor development. (2007) (1250)
Macrophage polarization comes of age. (2005) (1141)
Macrophage polarization in tumour progression. (2008) (1113)
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. (2014) (993)
The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. (2008) (909)
Regulation of the Chemokine Receptor CXCR4 by Hypoxia (2003) (865)
Role of tumor-associated macrophages in tumor progression and invasion (2006) (833)
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). (2006) (713)
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter (1995) (671)
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB (2009) (588)
The Yin‐Yang of tumor‐associated macrophages in neoplastic progression and immune surveillance (2008) (586)
Cancer related inflammation: the macrophage connection. (2008) (548)
Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF-κB Activation in Tumor-Associated Macrophages1 (2000) (473)
p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. (2006) (469)
New vistas on macrophage differentiation and activation (2007) (455)
Macrophage polarization in pathology (2015) (425)
Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms1 (2008) (409)
Interaction of NF-κB and NFAT with the Interferon-γ Promoter* (1997) (408)
Pathways connecting inflammation and cancer. (2008) (399)
Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor. (1990) (378)
A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships. (2009) (352)
Macrophage plasticity and polarization in liver homeostasis and pathology (2014) (351)
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. (2009) (343)
Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. (2004) (330)
Macrophage activation and polarization as an adaptive component of innate immunity. (2013) (329)
Bacterial Lipopolysaccharide Rapidly Inhibits Expression of C–C Chemokine Receptors in Human Monocytes (1997) (326)
Epidermal Growth Factor and Hypoxia-induced Expression of CXC Chemokine Receptor 4 on Non-small Cell Lung Cancer Cells Is Regulated by the Phosphatidylinositol 3-Kinase/PTEN/AKT/Mammalian Target of Rapamycin Signaling Pathway and Activation of Hypoxia Inducible Factor-1α* (2005) (298)
Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation. (2002) (287)
Interleukin 10 Increases CCR5 Expression and HIV Infection in Human Monocytes (1998) (265)
Cellular and molecular pathways linking inflammation and cancer. (2009) (258)
M2 Macrophages Phagocytose Rituximab-Opsonized Leukemic Targets More Efficiently than M1 Cells In Vitro1 (2009) (251)
Interaction of NF-kappaB and NFAT with the interferon-gamma promoter. (1997) (236)
Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors. (2004) (208)
Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB. (2009) (207)
Expression of monocyte chemotactic protein and interleukin-8 by cytokine-activated human vascular smooth muscle cells. (1991) (206)
The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65. (1993) (201)
The chemokine receptor switch paradigm and dendritic cell migration: its significance in tumor tissues (2000) (197)
Molecular and epigenetic basis of macrophage polarized activation. (2015) (190)
IL-1 transcriptionally activates the neutrophil chemotactic factor/IL-8 gene in endothelial cells. (1990) (180)
Divergent effects of hypoxia on dendritic cell functions. (2008) (168)
Characterization of the Promoter for the Human Long Pentraxin PTX3 (1997) (159)
Inflammation and cancer: breast cancer as a prototype. (2007) (154)
Negative Transcriptional Regulation of the Interferon-γ Promoter by Glucocorticoids and Dominant Negative Mutants of c-Jun (*) (1995) (151)
Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-gamma. (1998) (148)
Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha. (2005) (147)
RORC1 Regulates Tumor-Promoting "Emergency" Granulo-Monocytopoiesis. (2015) (144)
Defective Expression of the Monocyte Chemotactic Protein-1 Receptor CCR2 in Macrophages Associated with Human Ovarian Carcinoma1 (2000) (142)
Myeloid suppressor cells in cancer and autoimmunity. (2017) (140)
The c-rel protooncogene product c-Rel but not NF-kappa B binds to the intronic region of the human interferon-gamma gene at a site related to an interferon-stimulable response element. (1992) (131)
Modulation of peripheral blood immune cells by early use of steroids and its association with clinical outcomes in patients with metastatic non-small cell lung cancer treated with immune checkpoint inhibitors (2019) (129)
Tumor-associated macrophages: a molecular perspective. (2002) (128)
Redox regulation of chemokine receptor expression. (2000) (123)
Gradual loss of T-helper 1 populations in spleen of mice during progressive tumor growth. (1995) (123)
Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies (2016) (117)
Role of tumour-associated macrophages in cancer-related inflammation. (2010) (114)
Expression of a heat-inducible gene of the HSP70 family in human myelomonocytic cells: regulation by bacterial products and cytokines. (1991) (114)
Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages. (2017) (113)
Choosing wisely first line immunotherapy in non-small cell lung cancer (NSCLC): what to add and what to leave out. (2019) (111)
Circulating Exosomes Are Strongly Involved in SARS-CoV-2 Infection (2021) (106)
Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokines. (1991) (105)
Mechanisms linking pathogens-associated inflammation and cancer. (2011) (102)
Regulation of PD-L1 Expression by NF-κB in Cancer (2020) (102)
Tumor promotion by tumor-associated macrophages. (2007) (99)
Alterations in NF kappa B/Rel family proteins in splenic T-cells from tumor-bearing mice and reversal following therapy. (1994) (94)
A chemoattractant expressed in human sarcoma cells (tumor‐derived chemotactic factor, TDCF) is identical to monocyte chemoattractant protein‐1/monocyte chemotactic and activating factor (MCP‐1/MCAF) (1990) (90)
Inflammation as target in cancer therapy. (2017) (89)
Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7‐dependent manner (2014) (88)
Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. (2013) (87)
Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense. (2002) (86)
Cell-specific Regulation of PTX3 by Glucocorticoid Hormones in Hematopoietic and Nonhematopoietic Cells* (2008) (84)
Hypoxia-mediated regulation of macrophage functions in pathophysiology. (2013) (81)
Origin and Functions of Tumor-Associated Myeloid Cells (TAMCs) (2012) (81)
MCP‐1 and CCR2 in HIV infection: regulation of agonist and receptor expression (1997) (78)
Kappa B site-dependent activation of the interleukin-2 receptor alpha-chain gene promoter by human c-Rel (1992) (75)
Targeting tumour-associated macrophages (2007) (71)
Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. (2004) (70)
miR-146a and NF-κB1 Regulate Mast Cell Survival and T Lymphocyte Differentiation (2012) (68)
Myeloid-Derived Suppressor Cells: Ductile Targets in Disease (2019) (67)
Tumor-Associated Macrophages and Dendritic Cells as Prototypic Type II Polarized Myeloid Populations (2003) (64)
Hypoxia: a double-edged sword of immunity (2011) (63)
Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs (2020) (59)
Retinoic Acid-induced Transcriptional Modulation of the Human Interferon-γ Promoter* (1996) (58)
Expression of CD4 on human peripheral blood neutrophils. (2003) (58)
Activated macrophages release microvesicles containing polarized M1 or M2 mRNAs (2014) (58)
Microenvironmental control of malignancy exerted by RNASET2, a widely conserved extracellular RNase (2010) (56)
Activation of Nuclear Factor of Activated T Cells in a Cyclosporin A-resistant Pathway (*) (1996) (55)
Expression of c-jun protooncogene in human myelomonocytic cells. (1989) (52)
Targeting Cancer Cells and Tumor Microenvironment in Preclinical and Clinical Models of Hodgkin Lymphoma Using the Dual PI3Kδ/γ Inhibitor RP6530 (2018) (52)
Correction tp Macrophage activation and polarization: Nomenclature and experimental guidelines [Immunity, 41, 2014 (14-20)] (2014) (51)
Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization (2013) (51)
Tumor‐associated myeloid cells: new understandings on their metabolic regulation and their influence in cancer immunotherapy (2018) (47)
Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation (2013) (47)
Linking inflammation reactions to cancer: novel targets for therapeutic strategies. (2008) (46)
Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells. (2019) (45)
Angiostatin anti-angiogenesis requires IL-12: The innate immune system as a key target (2009) (45)
Regulation of macrophage function in tumors: the multifaceted role of NF- B (2009) (44)
Tumor-associated myeloid cells as guiding forces of cancer cell stemness (2017) (42)
Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 89.6 in monocytes exposed to glucocorticoid hormones. (1999) (42)
Enhanced interferon regulatory factor 3 binding to the interleukin-23p19 promoter correlates with enhanced interleukin-23 expression in systemic lupus erythematosus. (2012) (41)
Energy metabolism drives myeloid‐derived suppressor cell differentiation and functions in pathology (2017) (40)
Lipid Metabolism and Cancer Immunotherapy: Immunosuppressive Myeloid Cells at the Crossroad (2020) (37)
Heme catabolism by tumor-associated macrophages controls metastasis formation (2021) (36)
Protumor Steering of Cancer Inflammation by p50 NF-κB Enhances Colorectal Cancer Progression (2018) (35)
Convergent pathways of macrophage polarization: The role of B cells (2010) (34)
SPARC Is a New Myeloid-Derived Suppressor Cell Marker Licensing Suppressive Activities (2019) (34)
Macrophages in cancer and infectious diseases: the 'good' and the 'bad'. (2011) (33)
Endothelial cells express the interleukin-1 receptor type I (1991) (30)
Myelopoiesis, metabolism and therapy: a crucial crossroads in cancer progression (2019) (29)
VEGF blockade enhances the antitumor effect of BRAFV 600E inhibition (2016) (28)
Metabolic regulation of suppressive myeloid cells in cancer. (2017) (27)
Nonsense mutations affect C1 inhibitor messenger RNA levels in patients with type I hereditary angioneurotic edema. (1991) (27)
IL‐10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF‐κB p50 member in Trypanosoma congolense infection‐resistant C57BL/6 mice (2011) (26)
Inactivation of junctional adhesion molecule-A enhances antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration. (2010) (25)
Metabolic influence on the differentiation of suppressive myeloid cells in cancer. (2018) (23)
GADD45β Loss Ablates Innate Immunosuppression in Cancer. (2017) (23)
Divergent effects of dithiocarbamates on AP‐1‐containing and AP‐1‐less NFAT sites (1999) (22)
Immunosenescence, Inflammaging, and Frailty: Role of Myeloid Cells in Age-Related Diseases (2022) (21)
developmental relationships embryonic macrophages suggests common functions and Tie 2-expressing monocytes , blood ' ' resident ' ' monocytes , and A distinguishing gene signature shared by tumor-infiltrating (2009) (21)
Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages (2020) (21)
Retinoic acid-induced transcriptional modulation of the human interferon-gamma promoter. (1996) (20)
The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity (2012) (20)
Immunometabolic Status of COVID-19 Cancer Patients (2020) (20)
Influence of Innate Immunity on Cancer Cell Stemness (2020) (19)
Endothelial cells express the interleukin-1 receptor type I. (1991) (18)
The Macrophages-Microbiota Interplay in Colorectal Cancer (CRC)-Related Inflammation: Prognostic and Therapeutic Significance (2020) (17)
Interleukin-6 gene expression and production induced in human monocytes by membrane proteoglycans from Klebsiella pneumoniae. (1990) (17)
Tumor-associated macrophages (TAMs) as new target in anticancer therapy (2006) (16)
Cellular and molecular pathways linking inflammation and cancer. Immunobiology (2009) (14)
Implications of metabolism-driven myeloid dysfunctions in cancer therapy (2020) (14)
Choosing the Best Chemotherapy Agent to Boost Immune Checkpoint Inhibition Activity. (2018) (11)
Impact of cholesterolemia and body mass index on outcome of metastatic non small cell lung cancer treated with immunotherapy. (2019) (9)
Oncolytic virotherapy: new weapon for breast cancer treatment (2020) (8)
A PROTEOMIC ANALYSIS OF GSD-1a IN MOUSE LIVERS: EVIDENCE FOR METABOLIC REPROGRAMMING, INFLAMMATION AND MACROPHAGE POLARIZATION. (2019) (8)
LPS‐inducible nuclear factor in human monocytes that binds the negative regulatory element of the HIV LTR (1994) (8)
The role of cytokines as communication signals between leukocytes and endothelial cells. (1990) (8)
Membrane Cholesterol Regulates Macrophage Plasticity in Cancer. (2019) (8)
Tolerance in intestinal inflammation and cancer. (2008) (7)
Macrophages give Gas(6) to cancer. (2010) (7)
Macrophage fusion cuisine. (2009) (7)
Tumors as a Paradigm for the In Vivo Role of Chemokines in Leukocyte Recruitment (1999) (5)
Retinoic Acid-induced Transcriptional Modulation of the Human Interferon-g Promoter* (1996) (5)
The Inflammatory Milieu of Tumors: Cytokines and Chemokines that Affect Tumor Growth and Metastasis (2018) (4)
Precision Medicine Approaches with Metabolomics and Artificial Intelligence (2022) (3)
Role of Tumor‐Associated Macrophages (TAM) in Cancer Related Inflammation (2010) (3)
RORC 1 Regulates Tumor-Promoting ‘ ‘ Emergency ’ ’ Granulo-Monocytopoiesis Graphical Abstract Highlights (3)
Retraction notice to: Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. (2014) (3)
The interleukin 2 CD 28-responsive complex contains at least three members of the NF cB family : c-Rel , p 50 , and p 65 (2005) (3)
Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis (2022) (3)
NF-KappaB-Mediated Regulation of Tumour-Associated Macrophages: Mechanisms and Significance (2011) (3)
Tumor-Infiltrating Inflammatory Cells as Possible Therapeutic Targets (2012) (3)
Tumor-Associated Macrophages (2014) (2)
Tumor-Associated Macrophages in Cancer Growth and Progression (2007) (2)
Response to Hellstrand: The jury on radicals is still out (2003) (2)
Evolution and Targeting of Myeloid Suppressor Cells in Cancer: A Translational Perspective (2022) (2)
The Yin Yang of Cancer Related Inflammation (2011) (2)
Title: Enhanced interferon regulatory factor 3 binding to the IL-23p19 promoter correlates with enhanced IL-23 expression in systemic lupus erythematosus. Running Title: IRF3-IL-23p19 promoter interaction in SLE (2011) (1)
Abstract 393: Nicotinamide phosphoribosyl transferase (NAMPT) inhibitors: novel modulators of antitumor immunity (2015) (1)
Antitumor Resistance Macrophages Inhibits M 1 Inflammatory Responses and B Overexpression in Tumor-Associated κ p 50 Nuclear Factor-Updated (2006) (1)
MacrophagesActivation in Tumor-Associated B k Defective IL-12 Production and NF-Autocrine Production of IL-10 Mediates (1999) (1)
Chapter 27 – Tumor-associated Macrophages in Cancer Growth and Progression (2013) (1)
Inflammation and cancer: From bench to bedside? (2007) (1)
166 p50 NF-κB overexpression in tumor associated macrophages inhibits M1 inflammatory responses and antitumor resistance (2008) (1)
Circulating Fatty Acid Profile as a Biomarker for Immunotherapy in Advanced Non-Small Cell Lung Cancer. (2022) (1)
2 Functions of Diverse Myeloid Cells in the Tumor MicroEnvironment (2017) (0)
Molecular Mechanisms Tumor Progression: Regulation by Distinct Plasticity of Macrophage Function during (2008) (0)
SP0104 Reprogramming of myeloid cells in cancer: mechanisms and significance (2017) (0)
The in vivo tumor antagonizing role of human RNASET2 is mediated by host stromal cells recruitment (2009) (0)
Macrophages (PP-047) (2010) (0)
Dendritic cells: function (PP-024) (2010) (0)
The Immunoglobulin Heavy Chain Gene 2122 1 8 M a R C H 2 0 1 0 I V O L U M E 1 1 5 , N U M B E R 1 1 Blood (0)
Tumor antagonizing genes and ovarian cancer: the role of the human RNASET2 gene. (2011) (0)
296 Macrophage migration in tolerance (2010) (0)
Abstract 2677: Role of CLEC4D in inflammation-driven liver carcinogenesis (2017) (0)
Immunometabolic interference between cancer and COVID-19 (2023) (0)
Correction: Convergent pathways of macrophage polarization: The role of B cells (2010) (0)
Role of p50 NF-kappaB in dendritic cells functions (2008) (0)
Modulation of p50 NF-kappaB activity in TAM and TADC : a possible novel strategy to restore antitumor functions in vivo (2007) (0)
Host metabolic factors and prognosis in patients treated with immune checkpoint inhibitors for advanced malignancies. (2019) (0)
MiR-146 a and NF-kB 1 regulate mast cell survival and T lymphocyte 1 differentiation 2 3 4 (2012) (0)
Cancer immunity and immunotherapy beyond COVID-19 (2023) (0)
Cancer bio-immunotherapy XVIII annual NIBIT-(Italian network for tumor biotherapy) meeting, October 15–16, 2020 (2022) (0)
The c-rel protooncogene product c-Rel but not NF-KB (2004) (0)
PD-L1 status and efficacy of immune check-point inhibitors (ICIs) in advanced cancer patients: A pooled analysis of randomized trials. (2020) (0)
Regulation of Inflammatory Cytokine Receptor Expression by Pro- and Anti-Inflammatory Molecules (1998) (0)
IRF-3/STAT1 activation B and enhanced κ tumor-associated macrophages: defective NF- A distinct and unique transcriptional programme expressed by (2013) (0)
Cancer bio-immunotherapy XVII annual NIBIT (Italian Network for Tumor Biotherapy) meeting, October 11–13 2019, Verona, Italy (2021) (0)
NF‐κBとNFATのインターフェロン‐γのプロモータとの相互作用 (1997) (0)
Ovarian Carcinoma Macrophages Associated with Human Chemotactic Protein-1 Receptor CCR 2 in Defective Expression of the Monocyte (1999) (0)
Nicotinamide Phosphoribosyl Transferase ( NAMPT ) Inhibitors : Novel Modulators of Cancer-Related Inflammation (2013) (0)
T Lymphocyte Infiltration Antitumoral Immune Response by Promoting Dendritic Cell Inactivation of Junctional Adhesion Molecule-A Enhances (2010) (0)
Abstract 1871: Targeting nicotinamide phosphoribosyltransferase (NAMPT) in cancer therapy. (2013) (0)
PS2-039. The p50 NF-κB subunit controls dendritic cell survival and immunogenicity (2011) (0)
PP-046-32 IL-32g induces maturation of dendritic cells through a NF-kB/p38 MAPK signaling pathway (2010) (0)
The central nervous system microenvironment imprints microglial inability to switch from pro- to anti-inflammatory phenotype (2014) (0)
IL-21 and T follicular helper cells (2013) (0)
Abstract PR04: Targeting tumor-asoociated macrophages with a novel anti-CSF1R antibody in cancer patients (2015) (0)
Abstract P3-05-09: mRNA expression level and prognostic significance of different immune-related biomarkers in early breast cancer (2020) (0)
Macrophages (WS-047) Chairpersons: Masato Tanaka, Anna Erdei (2010) (0)
More Efficiently than M 1 Cells In Vitro Rituximab-Opsonized Leukemic Targets M 2 Macrophages Phagocytose (2009) (0)
Functions of Diverse Myeloid Cells in the Tumor Micro-Environment (2012) (0)
IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-jB p50 member in Trypanosoma congolense infection-resistant C57BL/6 mice: Eur. J. Immunol. 2011 41:1-11 (2011) (0)
Macrophage polarization in pathology (2015) (0)
The p50 NF-κB subunit is a prognostic regulator of colorectal cancer-associated inflammation (2016) (0)
Modulation of Innate Immunity by Hypoxia (2016) (0)

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What Schools Are Affiliated With Antonio Sica?

Antonio Sica is affiliated with the following schools: