Ariela Benigni
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Computer Science
Ariela Benigni's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science Stanford University
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(Suggest an Edit or Addition)Ariela Benigni's Published Works
Published Works
- Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. (2004) (748)
- Understanding the nature of renal disease progression. (1997) (660)
- Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes. (2006) (599)
- Angiotensin II revisited: new roles in inflammation, immunology and aging (2010) (584)
- Disruption of the Ang II type 1 receptor promotes longevity in mice. (2009) (447)
- Immunity, endothelial injury and complement-induced coagulopathy in COVID-19 (2020) (384)
- Human Bone Marrow Mesenchymal Stem Cells Accelerate Recovery of Acute Renal Injury and Prolong Survival in Mice (2008) (369)
- Cyclosporin-induced endothelial cell injury. (1986) (338)
- Insulin-like growth factor-1 sustains stem cell mediated renal repair. (2007) (306)
- Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells. (2013) (300)
- Recommendations for Biomarker Identification and Qualification in Clinical Proteomics (2010) (298)
- Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury. (2015) (295)
- MicroRNAs in kidney physiology and disease (2015) (294)
- Should COVID-19 Concern Nephrologists? Why and to What Extent? The Emerging Impasse of Angiotensin Blockade (2020) (268)
- The case of complement activation in COVID-19 multiorgan impact (2020) (264)
- A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression. (1993) (250)
- Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteins. (1995) (249)
- Enhanced nitric oxide synthesis in uremia: implications for platelet dysfunction and dialysis hypotension. (1993) (238)
- Anti-Phospholipase A2 Receptor Antibody Titer Predicts Post-Rituximab Outcome of Membranous Nephropathy. (2015) (237)
- MYO1E mutations and childhood familial focal segmental glomerulosclerosis. (2011) (229)
- Calcium channel blockers protect transplant patients from cyclosporine-induced daily renal hypoperfusion. (1993) (220)
- Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat. (2003) (202)
- Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporin A. (1986) (195)
- Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression. (1993) (186)
- Nonviral gene delivery to the rat kidney with polyethylenimine. (1997) (182)
- Renal and systemic nitric oxide synthesis in rats with renal mass reduction. (1997) (177)
- Life‐Sparing Effect of Human Cord Blood‐Mesenchymal Stem Cells in Experimental Acute Kidney Injury (2010) (175)
- Mapping the Theories of Preeclampsia and the Role of Angiogenic Factors: A Systematic Review (2007) (174)
- Sirtuins in Renal Health and Disease. (2018) (174)
- Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis. (2009) (174)
- Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension. (1989) (172)
- Daily renal hypoperfusion induced by cyclosporine in patients with renal transplantation. (1992) (169)
- Reduced platelet thromboxane formation in uremia. Evidence for a functional cyclooxygenase defect. (1983) (169)
- Increased renal endothelin production in rats with reduced renal mass. (1991) (168)
- Recellularization of well-preserved acellular kidney scaffold using embryonic stem cells. (2014) (168)
- Endothelin antagonists (1999) (166)
- In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies. (2005) (163)
- l-Arginine Depletion in Preeclampsia Orients Nitric Oxide Synthase Toward Oxidant Species (2004) (160)
- New therapeutics that antagonize endothelin: promises and frustrations (2002) (158)
- Protein traffic activates NF-kB gene signaling and promotes MCP-1-dependent interstitial inflammation. (2000) (157)
- In vivo maturation of functional renal organoids formed from embryonic cell suspensions. (2012) (157)
- Cellular responses to protein overload: key event in renal disease progression (2004) (149)
- Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis. (2001) (148)
- Fluid shear stress modulates von Willebrand factor release from human vascular endothelium. (1997) (148)
- Combining an antiproteinuric approach with mycophenolate mofetil fully suppresses progressive nephropathy of experimental animals. (1999) (145)
- Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury. (2006) (143)
- Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion. (2005) (143)
- Constitutive expression of endothelin gene in cultured human mesangial cells and its modulation by transforming growth factor-beta, thrombin, and a thromboxane A2 analogue. (1991) (133)
- Protein overload induces fractalkine upregulation in proximal tubular cells through nuclear factor kappaB- and p38 mitogen-activated protein kinase-dependent pathways. (2003) (131)
- Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR. (2003) (131)
- Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy. (2004) (130)
- Bone marrow-derived mesenchymal stem cells improve islet graft function in diabetic rats. (2009) (129)
- Unlike each drug alone, lisinopril if combined with avosentan promotes regression of renal lesions in experimental diabetes. (2009) (125)
- Podocyte–actin dynamics in health and disease (2016) (125)
- The Nrf2 pathway in the progression of renal disease. (2014) (120)
- Unselective inhibition of endothelin receptors reduces renal dysfunction in experimental diabetes. (1998) (117)
- ACE inhibition reduces glomerulosclerosis and regenerates glomerular tissue in a model of progressive renal disease. (2006) (116)
- Outrageous prices of orphan drugs: a call for collaboration (2018) (114)
- Angiotensin II modulates glomerular capillary permselectivity in rat isolated perfused kidney. (1996) (113)
- Blocking both type A and B endothelin receptors in the kidney attenuates renal injury and prolongs survival in rats with remnant kidney. (1996) (111)
- Endothelins in the control of cardiovascular and renal function (1993) (110)
- Human amniotic fluid stem cell preconditioning improves their regenerative potential. (2012) (109)
- Shigatoxin-induced endothelin-1 expression in cultured podocytes autocrinally mediates actin remodeling. (2006) (103)
- Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function (2017) (103)
- Inhibiting angiotensin-converting enzyme promotes renal repair by limiting progenitor cell proliferation and restoring the glomerular architecture. (2011) (102)
- Kidney regeneration (2010) (102)
- A Novel Strategy to Enhance Mesenchymal Stem Cell Migration Capacity and Promote Tissue Repair in an Injury Specific Fashion (2013) (100)
- Analogs of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects. (2013) (99)
- Nature and mediators of renal lesions in kidney transplant patients given cyclosporine for more than one year. (1999) (98)
- Upregulation of renal and systemic cyclooxygenase-2 in patients with active lupus nephritis. (1998) (95)
- Mesenchymal stem cells and kidney repair. (2013) (94)
- MicroRNAs as Master Regulators of Glomerular Function in Health and Disease. (2017) (93)
- Present and future drug treatments for chronic kidney diseases: evolving targets in renoprotection (2008) (93)
- Renal Expression of FGF23 in Progressive Renal Disease of Diabetes and the Effect of Ace Inhibitor (2013) (93)
- THE ACUTE EFFECT OF FK506 AND CYCLOSPORINE ON ENDOTHELIAL CELL FUNCTION AND RENAL VASCULAR RESISTANCE (1992) (92)
- Effect of angiotensin II antagonism on the regression of kidney disease in the rat. (2002) (90)
- Imaging of the porous ultrastructure of the glomerular epithelial filtration slit. (2010) (90)
- Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides. (2009) (89)
- SGLT2 inhibitor dapagliflozin limits podocyte damage in proteinuric nondiabetic nephropathy. (2018) (88)
- MicroRNA-324-3p promotes renal fibrosis and is a target of ACE inhibition. (2012) (87)
- Reversible activation defect of the platelet glycoprotein IIb-IIIa complex in patients with uremia. (1993) (85)
- Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury (2015) (83)
- Mesenchymal stem cell therapy promotes renal repair by limiting glomerular podocyte and progenitor cell dysfunction in adriamycin-induced nephropathy. (2012) (82)
- Renoprotective effect of contemporary blocking of angiotensin II and endothelin-1 in rats with membranous nephropathy. (1998) (82)
- Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone. (2006) (81)
- Effect of short-term cyclosporine administration in rats on renin-angiotensin and thromboxane A2: possible relevance to the reduction in glomerular filtration rate. (1986) (77)
- The renal toxicity of sustained glomerular protein traffic. (1995) (77)
- Systemic and fetal–maternal nitric oxide synthesis in normal pregnancy and pre‐eclampsia (1996) (76)
- Early histological changes in the kidney of people with morbid obesity. (2009) (75)
- The Regenerative Potential of Stem Cells in Acute Renal Failure (2006) (75)
- Extracellular vesicles derived from T regulatory cells suppress T cell proliferation and prolong allograft survival (2017) (74)
- CTLA4Ig gene transfer prolongs survival and induces donor-specific tolerance in a rat renal allograft. (2000) (74)
- Recombinant human erythropoietin to correct uremic bleeding. (1991) (72)
- Acute cyclosporine A nephrotoxicity in rats: which role for renin-angiotensin system and glomerular prostaglandins? (1986) (72)
- Nephrotoxicity of increased glomerular protein traffic. (1999) (71)
- MODERATE DOSES OF ASPIRIN AND RISK OF BLEEDING IN RENAL FAILURE (1986) (71)
- Increased urinary excretion of thromboxane B2 and 2,3-dinor-TxB2 in cyclosporin A nephrotoxicity. (1988) (70)
- Aging and the renin-angiotensin system. (2012) (70)
- How renal cytokines and growth factors contribute to renal disease progression. (2001) (68)
- Endothelin induces diuresis and natriuresis in the rat by acting on proximal tubular cells through a mechanism mediated by lipoxygenase products. (1991) (67)
- Key fibrogenic mediators: old players. Renin–angiotensin system (2014) (67)
- Membranous nephropathy associated with IgG4-related disease. (2011) (66)
- β-arrestin-1 drives endothelin-1-mediated podocyte activation and sustains renal injury. (2014) (66)
- Involvement of renal tubular Toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus. (2007) (66)
- Blunted excretory response to atrial natriuretic peptide in experimental nephrosis. (1989) (65)
- Angiotensin receptors as determinants of life span (2009) (65)
- Protein Overload Activates Proximal Tubular Cells to Release Vasoactive and Inflammatory Mediators (1999) (65)
- Role of anti-TGF-β antibodies in the treatment of renal injury (2006) (64)
- Coagulation abnormalities in uremia. (1985) (64)
- Distinct cardiac and renal effects of ETA receptor antagonist and ACE inhibitor in experimental type 2 diabetes. (2011) (64)
- Generation of functional podocytes from human induced pluripotent stem cells (2016) (63)
- Acute intradialytic well-being: results of a clinical trial comparing polysulfone with cuprophan. Bergamo Collaborative Dialysis Study Group. (1991) (61)
- Nature and mediators of parietal epithelial cell activation in glomerulonephritides of human and rat. (2013) (60)
- Role of increased glomerular protein traffic in the progression of renal failure. (1997) (59)
- Time course and localization of endothelin-1 gene expression in a model of renal disease progression. (1997) (58)
- Biomarkers of Fabry disease nephropathy. (2010) (58)
- Kidney failure: aims for the next 10 years and barriers to success (2013) (57)
- Vasopeptidase inhibitor restores the balance of vasoactive hormones in progressive nephropathy. (2004) (56)
- Evaluation of the Zucker Diabetic Fatty (ZDF) Rat as a Model for Human Disease Based on Urinary Peptidomic Profiles (2012) (55)
- Adding a statin to a combination of ACE inhibitor and ARB normalizes proteinuria in experimental diabetes, which translates into full renoprotection. (2010) (55)
- Pharmacologic control of angiotensin II ameliorates renal disease while reducing renal TGF-beta in experimental mesangioproliferative glomerulonephritis. (1998) (54)
- Indomethacin reduces proteinuria in passive Heymann nephritis in rats. (1987) (54)
- Atrial Natriuretic Peptide and Prostacyclin Synergistically Mediate Hyperfiltration and Hyperperfusion of Diabetic Rats (1992) (54)
- Evidence against a pathogenetic role for endothelin in pre‐eclampsia (1992) (54)
- Functional Human Podocytes Generated in Organoids from Amniotic Fluid Stem Cells. (2016) (54)
- The Toll-IL-1R Member Tir8/SIGIRR Negatively Regulates Adaptive Immunity against Kidney Grafts1 (2009) (53)
- Antibody-mediated extraction/negative-ion chemical ionization mass spectrometric measurement of thromboxane B2 and 2,3-dinor-thromboxane B2 in human and rat urine. (1987) (53)
- Experimental Evaluation of Kidney Regeneration by Organ Scaffold Recellularization (2017) (52)
- Endothelin antagonists in renal disease. (2000) (52)
- Mitochondrial Sirtuin 3 and Renal Diseases (2016) (52)
- PARATHYROID HORMONE INHIBITS HUMAN PLATELET FUNCTION (1981) (51)
- Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy. (1991) (50)
- MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy (2017) (50)
- Angiotensin II Blockade Limits Tubular Protein Overreabsorption and the Consequent Upregulation of Endothelin 1 Gene in Experimental Membranous Nephropathy (1998) (50)
- Any value of podocyte B7-1 as a biomarker in human MCD and FSGS? (2016) (49)
- Platelet function in patients on maintenance hemodialysis: depressed or enhanced? (1982) (49)
- Cyclin-dependent kinase inhibition limits glomerulonephritis and extends lifespan of mice with systemic lupus. (2007) (49)
- Beneficial Effect of TGFβ Antagonism in Treating Diabetic Nephropathy Depends on When Treatment Is Started (2006) (49)
- Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis. (2001) (48)
- INCREASED URINARY EXCRETION OF ENDOTHELIN‐1 AND ITS PRECURSOR, BIG‐ENDOTHELIN-1, IN RATS CHRONICALLY TREATED WITH CYCLOSPORINE (1991) (48)
- An Ex Vivo Test of Complement Activation on Endothelium for Individualized Eculizumab Therapy in Hemolytic Uremic Syndrome. (2019) (47)
- Sirt3 deficiency shortens lifespan and impairs cardiac mitochondrial function rescued by Opa1 gene transfer. (2019) (47)
- Angiotensin-converting enzyme inhibition prevents glomerular-tubule disconnection and atrophy in passive Heymann nephritis, an effect not observed with a calcium antagonist. (2001) (47)
- Changes in glomerular perm-selectivity induced by angiotensin II imply podocyte dysfunction and slit diaphragm protein rearrangement. (2004) (47)
- Passive Heymann nephritis: evidence that angiotensin-converting enzyme inhibition reduces proteinuria and retards renal structural injury. (1996) (45)
- Targeted Downregulation of Extracellular Nephrin in Human IgA Nephropathy (2003) (44)
- Dendritic Cells Genetically Engineered with Adenoviral Vector Encoding dnIKK2 Induce the Formation of Potent CD4+ T-Regulatory Cells (2005) (43)
- Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity (2013) (42)
- Glomerular protein trafficking and progression of renal disease to terminal uremia. (1996) (42)
- Renoprotection by nitric oxide donor and lisinopril in the remnant kidney model. (1999) (41)
- Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway. (2013) (41)
- Mitochondrial Dynamics Is Linked to Longevity and Protects from End-Organ Injury: The Emerging Role of Sirtuin 3. (2016) (40)
- Thromboxane A2 receptor blocking abrogates donor-specific unresponsiveness to renal allografts induced by thymic recognition of major histocompatibility allopeptides (1994) (39)
- Targeted deletion of angiotensin II type 1A receptor does not protect mice from progressive nephropathy of overload proteinuria. (2004) (39)
- Glomerular Hyperfiltration and Urinary Prostaglandins in Type 1 Diabetes Mellitus (1989) (38)
- COVID-19 and lombardy: TESTing the impact of the first wave of the pandemic (2020) (38)
- Adeno-associated virus-mediated CTLA4Ig gene transfer protects MHC-mismatched renal allografts from chronic rejection. (2006) (38)
- ACE inhibition limits chronic injury of kidney transplant even with treatment started when lesions are established. (2003) (38)
- Effect on blood pressure of combined inhibition of endothelin-converting enzyme and neutral endopeptidase with daglutril in patients with type 2 diabetes who have albuminuria: a randomised, crossover, double-blind, placebo-controlled trial. (2013) (38)
- Polymorphisms of EDNRB, ATG, and ACE genes in salt-sensitive hypertension. (2008) (38)
- Regression of Renal Disease by Angiotensin II Antagonism Is Caused by Regeneration of Kidney Vasculature. (2016) (37)
- Endothelin: a mediator of renal disease progression. (1997) (37)
- Combined treatment with mycophenolate mofetil and an angiotensin II receptor antagonist fully protects from chronic rejection in a rat model of renal allograft. (2001) (36)
- Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy (2015) (36)
- B7-1 Is Not Induced in Podocytes of Human and Experimental Diabetic Nephropathy. (2016) (36)
- Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes (2020) (36)
- Erythropoietin, but not the correction of anemia alone, protects from chronic kidney allograft injury. (2012) (36)
- The metabolism of arachidonic acid by platelets in nephrotic syndrome. (1984) (34)
- Endothelin and eicosanoid synthesis in cultured mesangial cells. (1990) (33)
- Engineering the vasculature of decellularized rat kidney scaffolds using human induced pluripotent stem cell-derived endothelial cells (2019) (33)
- Immunophenotypic analysis of cellular infiltrate of renal allograft biopsies in patients with acute rejection after induction with alemtuzumab (Campath-1H). (2006) (33)
- Thromboxane synthesis inhibition increases renal prostacyclin and prevents renal disease progression in rats with remnant kidney. (1990) (32)
- Enhanced glomerular thromboxane A2 mediates some pathophysiologic effect of platelet-activating factor in rabbit nephrotoxic nephritis: evidence from biochemical measurements and inhibitor trials. (1989) (32)
- Therapeutic potential of TGF-β inhibition in chronic renal failure (2007) (31)
- Role of anti-TGF-beta antibodies in the treatment of renal injury. (2006) (31)
- C3a receptor blockade protects podocytes from injury in diabetic nephropathy. (2020) (31)
- ACE inhibition prevents renal failure and death in uninephrectomized MWF/Ztm rats. (1995) (31)
- Direct Reprogramming of Human Bone Marrow Stromal Cells into Functional Renal Cells Using Cell-free Extracts (2015) (30)
- Role of enhanced glomerular synthesis of thromboxane A2 in progressive kidney disease. (1990) (30)
- Defining the role of endothelins in renal pathophysiology on the basis of selective and unselective endothelin receptor antagonist studies (1995) (30)
- SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation (2022) (29)
- Endothelin antagonists and renal protection. (2000) (29)
- Therapeutic potential of stromal cells of non-renal or renal origin in experimental chronic kidney disease (2018) (29)
- Early and late scanning electron microscopy findings in diabetic kidney disease (2018) (29)
- DnIKK2-Transfected Dendritic Cells Induce a Novel Population of Inducible Nitric Oxide Synthase–Expressing CD4+CD25− Cells with Tolerogenic Properties (2007) (29)
- Rare Functional Variants in Complement Genes and Anti-FH Autoantibodies-Associated aHUS (2019) (29)
- Aging and the kidney (2011) (28)
- Primer: strategies for identifying genes involved in renal disease (2008) (28)
- Research on renal endothelin in proteinuric nephropathies dictates novel strategies to prevent progression (2001) (28)
- Unrecognized pattern of von Willebrand factor abnormalities in hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. (1999) (28)
- Addition of cyclic angiotensin-(1-7) to angiotensin-converting enzyme inhibitor therapy has a positive add-on effect in experimental diabetic nephropathy. (2019) (27)
- Renal Medicine 3 Kidney regeneration (2010) (27)
- Prolonged bleeding time and increased vascular prostacyclin in rats with chronic renal failure: effects of conjugated estrogens. (1988) (27)
- Unraveling the Molecular Mechanisms Underlying Complement Dysregulation by Nephritic Factors in C3G and IC-MPGN (2018) (27)
- Complement Alternative Pathway Deficiency in Recipients Protects Kidney Allograft From Ischemia/Reperfusion Injury and Alloreactive T Cell Response (2017) (26)
- BRAF Signaling Pathway Inhibition, Podocyte Injury, and Nephrotic Syndrome. (2017) (26)
- Quantitative profiling of 6-ketoprostaglandin F1 alpha, 2,3-dinor-6-ketoprostaglandin F1 alpha, thromboxane B2 and 2,3-dinor-thromboxane B2 in human and rat urine by immunoaffinity extraction with gas chromatography-mass spectrometry. (1989) (25)
- Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated? (1985) (24)
- Role of renal prostaglandins in normal and nephrotic rats with diet-induced hyperfiltration. (1986) (24)
- Glomerular filtration rate gfr extracellular fluid volume ecv and atrial natriuretic factor anf in insulin dependent diabetics (1988) (24)
- Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery (2018) (24)
- Effect of Low-Dose Aspirin on Fetal and Maternal Generation of Thromboxane by Platelets in Women at Risk for Pregnancy-Induced Hypertension (1990) (23)
- Effect of aspirin and sulindac in rabbit nephrotoxic nephritis. (1986) (23)
- Rabbit anti‐rat thymocyte immunoglobulin preserves renal function during ischemia/reperfusion injury in rat kidney transplantation (2011) (23)
- The role of B7-1 in proteinuria of glomerular origin (2018) (22)
- Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II (2015) (22)
- Differential inhibition by aspirin of platelet thromboxane and renal prostaglandins in the rat. (1989) (22)
- Renal prostacyclin biosynthesis is reduced in children with hemolytic-uremic syndrome in the context of systemic platelet activation. (1992) (22)
- Selective inhibition of platelet thromboxane generation with low-dose aspirin does not protect rats with reduced renal mass from the development of progressive disease. (1989) (22)
- Key pathways in renal disease progression of experimental diabetes. (2015) (22)
- Urinary excretion of platelet-activating factor in haemolytic uraemic syndrome (1992) (22)
- Data Sharing Under the General Data Protection Regulation (2021) (21)
- The Role of Angiotensin II in Parietal Epithelial Cell Proliferation and Crescent Formation in Glomerular Diseases. (2017) (21)
- Urinary excretion of platelet activating factor in patients with immune-mediated glomerulonephritis. (1993) (21)
- Therapeutic potential of TGF-beta inhibition in chronic renal failure. (2007) (21)
- C5a and C5aR1 are key drivers of microvascular platelet aggregation in clinical entities spanning from aHUS to COVID-19 (2021) (20)
- Endothelin receptor antagonists: which are the therapeutic perspectives in renal diseases? (1998) (20)
- Endothelin receptor selectivity in chronic renal failure (2009) (20)
- A previously unrecognized role of C3a in proteinuric progressive nephropathy (2016) (20)
- Et and diabetic nephropathy: preclinical and clinical studies. (2015) (19)
- Methylprednisolone dosage effects on peripheral lymphocyte subpopulations and eicosanoid synthesis. (1992) (19)
- Combining lisinopril and l-arginine slows disease progression and reduces endothelin-1 in passive Heymann nephritis. (2003) (19)
- Functional implications of decreased renal cortical atrial natriuretic peptide binding in experimental diabetes. (1990) (18)
- Increased concentrations of antiangiogenic factors in mirror syndrome complicating twin‐to‐twin transfusion syndrome (2010) (18)
- Mechanism of progression of renal disease: growth factors and related mechanisms. (1998) (17)
- α1-antitrypsin therapy in a case of thrombotic thrombocytopenic purpura (1995) (17)
- Renal Primordia Activate Kidney Regenerative Events in a Rat Model of Progressive Renal Disease (2015) (17)
- Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease (2015) (17)
- Evidence against a pathogenetic role for endothelin in preeclampsia (1993) (16)
- SYMPOSIUM Experimental Biology 1995 Endothelin Receptors: Role in Renal Function and Dysfunction ENDOTHELIN IS A KEY MODULATOR OF PROGRESSIVE RENAL INJURY: EXPERIMENTAL DATA AND NOVEL THERAPEUTIC STRATEGIES (1996) (16)
- Nonviral and Viral Gene Transfer to the Kidney in the Context of Transplantation (2000) (15)
- Gene therapy: how to target the kidney. Promises and pitfalls. (2004) (15)
- The potential of endothelin antagonism as a therapeutic approach (2004) (15)
- Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes. (2019) (15)
- Potential of mesenchymal stem cells in the repair of tubular injury (2011) (14)
- Endothelin in the progressive renal disease of glomerulopathies. (1995) (14)
- Endothelin in chronic proteinuric kidney disease. (2011) (14)
- Eculizumab in patients with severe coronavirus disease 2019 (COVID-19) requiring continuous positive airway pressure ventilator support: Retrospective cohort study (2021) (14)
- A new BEACON of hope for the treatment of inflammation? The endogenous metabolite itaconate as an alternative activator of the KEAP1-Nrf2 system. (2018) (13)
- Favorable Effect of Cotransfection with TGF-β and CTLA4Ig of the Donor Kidney on Allograft Survival (2004) (13)
- Renal metabolism and urinary excretion of thromboxane B2 in the rat. (1989) (12)
- Repairing renal lesions: will VEGF be the builder? (2000) (12)
- Preliminary report: renal thromboxane A2 synthesis in children with frequent relapsing nephrotic syndrome (1990) (11)
- CFH and CFHR Copy Number Variations in C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis (2021) (11)
- Abatacept in B7-1-positive proteinuric kidney disease. (2014) (11)
- The renoprotective potential of endothelin receptor antagonists (1997) (11)
- Inhibiting angiotensin-converting enzyme promotes renal repair by modulating progenitor cell activation. (2016) (11)
- Effects of Rosuvastatin on Glomerular Capillary Size-Selectivity Function in Rats with Renal Mass Ablation (2007) (11)
- The Nrf 2 pathway in the progression of renal disease (2014) (11)
- FK 506 does not affect the glomerular filtration rate and renal plasma flow in the rat. (1991) (11)
- Transplantation-Induced Ischemia-Reperfusion Injury Modulates Antigen Presentation by Donor Renal CD11c+F4/80+ Macrophages through IL-1R8 Regulation. (2020) (10)
- Post-transcriptional gene regulation makes things clearer in renal fibrosis. (2013) (9)
- Novel strategies to retard renal disease progression: combining ACE inhibition with endothelin receptor blocking? (1998) (9)
- Xenotransplantation in the 21st Century (2002) (9)
- Allograft rejection: acute and chronic studies. (2008) (9)
- A novel interpretation of the role of von Willebrand factor in thrombotic microangiopathies based on platelet adhesion studies at high shear rate flow. (2000) (9)
- Towards graft-specific immune suppression: Gene therapy of the transplanted kidney. (2010) (9)
- Progression of proteinuric diabetic and nondiabetic renal diseases: a possible role for renal endothelin. (1997) (9)
- Transplant tolerance: will genes protect the graft? (1998) (9)
- Tubulointerstitial disease mediators of injury: the role of endothelin. (2000) (9)
- An Unanticipated Role for Survivin in Organ Transplant Damage (2014) (9)
- Adenoviral-mediated gene transfer restores plasma ADAMTS13 antigen and activity in ADAMTS13 knockout mice (2009) (9)
- Impediments to successful gene transfer to the kidney in the context of transplantation and how to overcome them. (2002) (8)
- Local gene therapy with indoleamine 2,3-dioxygenase protects against development of transplant vasculopathy in chronic kidney transplant dysfunction (2016) (8)
- Empagliflozin protects glomerular endothelial cell architecture in experimental diabetes through the VEGF‐A/caveolin‐1/PV‐1 signaling pathway (2022) (8)
- Reply to the Comment by Dr. Cure on “Should COVID-19 Concern Nephrologists? Why and to What Extent? The Emerging Impasse of Angiotensin Blockade” (2020) (8)
- The role of vasoactive molecules of endothelial origin in the pathophysiology of normal pregnancy and pregnancy-induced hypertension. (1996) (8)
- Endothelin-targeted new treatments for proteinuric and inflammatory glomerular diseases: focus on the added value to anti-renin-angiotensin system inhibition (2020) (8)
- Metabolism of arachidonic acid in isolated glomeruli from pig kidney. (1988) (8)
- Another Piece of the Puzzle of Podocyte B7-1 Expression: Lupus Nephritis (2016) (8)
- Identification of a novel gene--SSK1--in human endothelial cells exposed to shear stress. (1998) (8)
- Impact of a Complement Factor H Gene Variant on Renal Dysfunction, Cardiovascular Events, and Response to ACE Inhibitor Therapy in Type 2 Diabetes (2019) (8)
- Molecular Studies and an ex vivo Complement Assay on Endothelium Highlight the Genetic Complexity of Atypical Hemolytic Uremic Syndrome: The Case of a Pedigree With a Null CD46 Variant (2020) (7)
- Role of ultrastructural determinants of glomerular permeability in ultrafiltration function loss. (2020) (7)
- ADAMTS13 Deficiency Shortens the Life Span of Mice With Experimental Diabetes (2018) (7)
- Autotaxin Inhibitor Protects from Chronic Allograft Injury in Rat Kidney Allotransplantation (2019) (7)
- Renin-angiotensin system and glomerular prostaglandins in early nephrotoxicity of ciclosporin. (1986) (7)
- Interleukin-6 stimulates gene expression of extracellular matrix components in bovine mesangial cells in culture (1993) (7)
- Metabolism of thromboxane B2 in the isolated perfused rat kidney: mass spectrometric identification of urinary products. (1989) (6)
- Proteins abnormally filtered throughout glomerular capillary have an intrinsic renal toxicity. (1996) (6)
- The role of eicosanoids in the pathogenesis of hemolytic uremic syndrome. (1994) (6)
- Untangling the Knot in Diabetic Nephropathy: The Unanticipated Role of Glycocalyx in the Antiproteinuric Effect of Endothelin Receptor Antagonists (2016) (6)
- The iNADequacy of renal cell metabolism: modulating NAD+ biosynthetic pathways to forestall kidney diseases. (2019) (6)
- Effect of Seliciclib (CYC202, R-Roscovitine) on Lymphocyte Alloreactivity and Acute Kidney Allograft Rejection in Rat (2008) (5)
- Pharmacological Induction of Kidney Regeneration (2017) (5)
- Drugs to Foster Kidney Regeneration in Experimental Animals and Humans (2014) (5)
- Genetics of rare diseases of the kidney: learning from mouse models (2004) (5)
- EGF receptor–mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling (2020) (5)
- Angiotensin-converting enzyme 2: from a vasoactive peptide to the gatekeeper of a global pandemic (2020) (5)
- Abnormalities of arachidonate metabolism in experimental ciclosporin nephrotoxicity. (1989) (5)
- Local gene therapy with indoleamine 2,3-dioxygenase protects against development of transplant vasculopathy in chronic kidney transplant dysfunction (2016) (5)
- Post-translational modifications by SIRT3 de-2-hydroxyisobutyrylase activity regulate glycolysis and enable nephrogenesis (2021) (4)
- The incessant search for renal biomarkers: is it really justified? (2019) (4)
- Treatment of chronic proteinuric kidney disease: what next? (2009) (4)
- CRISPR-Cas9-Mediated Correction of the G189R-PAX2 Mutation in Induced Pluripotent Stem Cells from a Patient with Focal Segmental Glomerulosclerosis. (2019) (4)
- Sirtuin 3 in acute kidney injury (2015) (4)
- Proteinuria and Tubulotoxicity (2018) (3)
- Human iPSC-derived neural crest stem cells can produce EPO and induce erythropoiesis in anemic mice. (2021) (3)
- Sirtuin 3 Deficiency Aggravates Kidney Disease in Response to High-Fat Diet through Lipotoxicity-Induced Mitochondrial Damage (2022) (3)
- Genes and molecular medicine in the future of organ transplantation (1999) (3)
- Role of eicosanoids as mediators of glomerular injury in immune-mediated nephropathies. (1989) (3)
- CYCLOSPORIN A (CyA) INDUCED ENDOTHELIAL CELL INJURY (1987) (3)
- Generation of two isogenic knockout PKD2 iPS cell lines, IRFMNi003-A-1 and IRFMNi003-A-2, using CRISPR/Cas9 technology. (2019) (3)
- Characterization of a Rat Model of Myeloperoxidase-Anti-Neutrophil Cytoplasmic Antibody-Associated Crescentic Glomerulonephritis (2021) (3)
- The goal of intragraft gene therapy. (2005) (3)
- Report on the first combined working group and management committee meeting of EuroKUP (Urine and Kidney Proteomics cost action). (2009) (3)
- Hemolytic Uremic Syndrome in an Infant with Primary Hyperoxaluria Type II: An Unreported Clinical Association (2019) (2)
- alpha 1-Antitrypsin therapy in a case of thrombotic thrombocytopenic purpura. (1995) (2)
- Generation of a homozygous CIITA knockout iPS cell line using the CRISPR-Cas9 system. (2021) (2)
- SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Thrombus Formation (2021) (2)
- Prevention of acute renal failure after aortic surgery. (1988) (2)
- The regenerative potential of stem cells in acute renal failure. (2006) (2)
- The Onset and Resolution of Renal Fibrosis: A Human Perspective (2016) (2)
- Gene therapy to the kidney. (2001) (1)
- 6th Update on Fabry Disease: Biomarkers, Progression and Treatment Opportunities (2019) (1)
- Sirtuins as key players in aging and kidney dysfunction (2021) (1)
- Prostacyclin and thromboxane and the development of preeclampsia. (2000) (1)
- Gene therapy for renal diseases and transplantation (2008) (1)
- Low Nephron Number Induced by Maternal Protein Restriction Is Prevented by Nicotinamide Riboside Supplementation Depending on Sirtuin 3 Activation (2022) (1)
- Inflammation and glomerular injury (2004) (1)
- Role of endothelin (ET) in the progression of renal disease (1990) (1)
- Membranous Nephropathy in IgG4-Related Disease (2015) (1)
- Cells for treating organ damage: how long will we need them? (2011) (1)
- Toll-like receptors in the development of renal injury in systemic lupus erythematosus (2009) (1)
- 6th Update on Fabry Disease: Biomarkers, Progression and Treatment Opportunities (2019) (1)
- Generation of PKD1 mono-allelic and bi-allelic knockout iPS cell lines using CRISPR-Cas9 system. (2020) (1)
- Imaging the Kidney with an Unconventional Scanning Electron Microscopy Technique: Analysis of the Subpodocyte Space in Diabetic Mice (2022) (1)
- Unravelling the molecular mechanisms underlying complement dysregulation by nephritic factors in C3G and IC-MPGN (2018) (1)
- Amnion epithelial cells are an effective source of factor H and prevent kidney complement deposition in factor H-deficient mice (2021) (1)
- Contents Vol. 137, 2017 (2017) (0)
- Therapeutic potential of stromal cells of non-renal or renal origin in experimental chronic kidney disease (2018) (0)
- Increased urinary excretion of thromboxane B 2 and 2 , 3-dinor-TxB 2 in cyclosporin A nephrotoxicity (2010) (0)
- Molecular Medicine in Organ Transplantation: How and When? (2001) (0)
- TimeCourseandLocalization ofEndothelin-1 Gene Expression ina ModelofRenalDisease Progression (1997) (0)
- Front & Back Matter (2017) (0)
- INCREASED SUSCEPTIBILITY TO INTESTINAL INFLAMMATION OF MICE DEFICIENT IN TIR8, AN INHIBITORY MEMBER OF IL-1 RECEPTOR FAMILY EXPRESSED IN EPITHELIAL AND DENDRITIC CELLS (2004) (0)
- Contents Vol. 85, 2000 (2000) (0)
- Decreased Nephron Number within Physiologic Ranges Increases Susceptibility to Chronic Renal Diseases Later in Life (2020) (0)
- Endothelin and renal disease progression. (1994) (0)
- Acknowledgment of Reviewers (2006) (0)
- Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity (2012) (0)
- P26.06: Increased concentrations of antiangiogenic factors in mirror syndrome complicating TTTS (2009) (0)
- Annual Author Index (2010) (0)
- Sirtuins and Longevity : Is RAS Dispensable ? (0)
- Shiga Toxin 2 Triggers C3a-Dependent Glomerular and Tubular Injury through Mitochondrial Dysfunction in Hemolytic Uremic Syndrome (2022) (0)
- Role of endothelin in progressive proteinuric nephropathies (2001) (0)
- Contents Vol. 27, 2007 (2007) (0)
- List of contributors (2021) (0)
- CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome (2023) (0)
- Inhibition Of Interleukin-8 (il-8) Activity Prevents Renal Function Deterioration Due To Ischemia/reperfusion In Syngeneic And Allogeneic Rat Kidney Transplantation. (2004) (0)
- ‘Remodeling' Nephron (2015) (0)
- Front & Back Matter (2017) (0)
- POS-037 ACTIVATION OF THE ALTERNATIVE PATHWAY OF COMPLEMENT FAVORS THROMBUS FORMATION ON MICROVASCULAR ENDOTHELIAL CELLS IN ACUTE HEMOLYTIC UREMIC SYNDROME INDUCED BY SHIGA-LIKE-TOXIN PRODUCING E.COLI (STEC-HUS) (2022) (0)
- Renal transplantation - basic research (2009) (0)
- Forefronts in endothelin. (2008) (0)
- Unravelling the Role of PAX2 Mutation in Human Focal Segmental Glomerulosclerosis (2021) (0)
- Engineering the vasculature of decellularized rat kidney scaffolds using human induced pluripotent stem cell-derived endothelial cells (2019) (0)
- Role of Transforming Growth Factor-β in the Kidney — Physiology and Pathology (2008) (0)
- Contents Vol. 141, 2019 (2019) (0)
- Genetic diseases and molecular genetics - 2 (2011) (0)
- Contents Vol. 139, 2018 (2018) (0)
- Subject Index Vol. 27, 2007 (2007) (0)
- Contents Vol. 138, 2018 (2018) (0)
- Generation of two isogenic iPS cell lines (IRFMNi002-A and IRFMNi002-B) from a patient affected by Focal Segmental Glomerulosclerosis carrying a heterozygous c.565G>A mutation in PAX2 gene (2018) (0)
- Thromboxane synthase inhibition increases urinary protein excretion in diabetic nephropathy (1993) (0)
- Editorial: Women in renal pharmacology: 2021 (2022) (0)
- Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes (2020) (0)
- Therapeutic Small Interfering RNA Targeting Complement C3 in a Mouse Model of C3 Glomerulopathy (2022) (0)
- Contributions to Nephrology: Preface (2008) (0)
- Prostanoid-Related Platelet Abnormalities in Renal Disease (1984) (0)
- An ex vivo test to investigate genetic factors conferring susceptibility to atypical haemolytic uremic syndrome (2023) (0)
- Potentially useful markers in identifying a population at risk for preeclampsia (1995) (0)
- Mechanisms of progression of renal disease and possible sites of action of n-3 fatty acids. (1993) (0)
- Author Index to Abstracts (1998) (0)
- AAV9-mediated engineering of autotransplanted kidney of non-human primates (2017) (0)
- Amnion epithelial cells are an effective source of factor H and prevent kidney complement deposition in factor H-deficient mice (2021) (0)
- 10th Annual Meeting of the European Renal Cell Study Group (1998) (0)
- Reviews submitted from September 1, 2012 through August 31, 2013 (2013) (0)
- POS-001 A NOVEL CFHR5 COPY NUMBER VARIATION ASSOCIATED WITH POST-PARTUM ATYPICAL HUS SUPERIMPOSED TO HELLP SYNDROME (2022) (0)
- Contents Vol. 105, 2004 (2004) (0)
- Genetic rearrangements in CFH and CFH-Related genes in atypical Hemolytic Uremic Syndrome, C3 glomerulopathy and Immuno-Complex mediated MPGN (2017) (0)
- Protective Effects of Human Nonrenal and Renal Stromal Cells and Their Conditioned Media in a Rat Model of Chronic Kidney Disease (2020) (0)
- Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function (2017) (0)
- Diabetes mellitus - basic research (2009) (0)
- Endothelin receptor antagonism versus combined ECE/NEP inhibition in patients with type 2 diabetes and nephropathy (2013) (0)
- Front & Back Matter (2018) (0)
- Contents Vol. 142, 2019 (2019) (0)
- Subject Index Vol. 7, 1999 (1999) (0)
- Life and Death of Podocytes: Not Only a Matter of Vascular Endothelial Growth Factor (2016) (0)
- Long-term adaptive response in COVID-19 vaccine recipients and the effect of a booster dose (2023) (0)
- Supplementary Material for: Another Piece of the Puzzle of Podocyte B7-1 Expression: Lupus Nephritis (2016) (0)
- Acknowledgments to Reviewers of Kidney Diseases 2018 (2018) (0)
- Subject Index Vol. 104, 2006 (2006) (0)
- Therapeutic Options for Preventing Transplant-Related Progressive Renal and Vascular Injury (2008) (0)
- Aspirin in Hypertension of Pregnancy (1992) (0)
- Renal prostaglandins and hyperfiltration. (1987) (0)
- Front & Back Matter (2017) (0)
- A platelet-activating factor receptor antagonist protects against renal function deterioration in nephrotoxic nephritis. (1987) (0)
- Translational Nephrology Will fish foster regenerative medicine in man ? (2011) (0)
- Front & Back Matter (2017) (0)
- Subject Index Vol. 85, 2000 (2000) (0)
- Contents Vol. 143, 2019 (2019) (0)
- Consultants for the American Journal of Nephrology 2007 (2007) (0)
- Immunophenotypic Alterations in Adult Patients with Steroid-Dependent and Frequently Relapsing Nephrotic Syndrome (2023) (0)
- Front & Back Matter (2018) (0)
- Front & Back Matter (2016) (0)
- Early and late scanning electron microscopy findings in diabetic kidney disease (2018) (0)
- Cardiovascular & Renal The renoprotective potential of endothelin receptor antagonists (1997) (0)
- Dendritic Cells (dcs) Genetically Engineered To Block Nf-kb Pathway Induce The Formation Of Potent Type-1-like T Regulatory Cells (treg) (2004) (0)
- Front & Back Matter (2014) (0)
- Mele-NEJM-2011-appendix (2012) (0)
- Front & Back Matter (2018) (0)
- Extracellular vesicles derived from T regulatory cells suppress T cell proliferation and prolong allograft survival (2017) (0)
- Front & Back Matter (2017) (0)
- CHAPTER 5. Regulation and Function of MicroRNAs in Kidney Diseases (2019) (0)
- The Editorial Office thanks the following colleagues for reviewing papers for the period of 1 November 2000 to 31 October 2001 (2002) (0)
- The Editorial Office thanks the following colleagues for reviewing papers for the period of 1 November 2000 to 31 October 2001 (2002) (0)
- Will fish foster regenerative medicine in man? (2011) (0)
- Acute renal failure - basic research (2009) (0)
- SP004INHIBITION OF THE C5A RECEPTOR BY CCX168 MARKEDLY REDUCES THE THROMBOGENIC POTENTIAL OF SERUM FROM PATIENTS WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME (2015) (0)
- Add-On Cyclic Angiotensin-(1-7) with Cyclophosphamide Arrests Progressive Kidney Disease in Rats with ANCA Associated Glomerulonephritis (2022) (0)
- Contents Vol. 104, 2006 (2006) (0)
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