Arnold Burgen

Q: What Schools Are Affiliated With Arnold Burgen

Arnold Burgen is affiliated with the following schools: McGill University, University of Oxford, University College London, University of Cambridge

Arnold Burgen's AcademicInfluence.com Rankings

Arnold Burgen

Chemistry

#1645

World Rank

#2414

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chemistry Degrees

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Chemistry

Arnold Burgen's Degrees

PhD Chemistry University of Oxford
Bachelors Chemistry University of Oxford

Why Is Arnold Burgen Influential?

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According to Wikipedia, Sir Arnold Stanley Vincent Burgen FRS was a British physician, pharmacologist, academic and university administrator. He was Master of Darwin College, Cambridge, from 1982–89, Deputy Vice-Chancellor of The University of Cambridge from 1985–89, and founding President of the Academia Europæa.

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Arnold Burgen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Pirenzepine distinguishes between different subclasses of muscarinic receptors (1980) (1266)
The binding of agonists to brain muscarinic receptors. (1978) (622)
The action of botulinum toxin on the neuro‐muscular junction (1949) (568)
The Responsibility to Protect Report of the International Commission on Intervention and State Sovereignty (2001) The International Development Research Centre, PO Box 8500, Ottawa ON, Canada K1G 3H9 (2002) (393)
Modification of the binding properties of muscarinic receptors by gallamine. (1983) (322)
The inhibition of noradrenaline uptake by sympathomimetic amines in the rat isolated heart. (1965) (274)
Guanine nucleotides modulate muscarinic receptor binding in the heart. (1979) (218)
On the negative inotropic effect in the cat's auricle (1953) (186)
Binding of flexible ligands to macromolecules (1975) (177)
Cholinesterase and succinic dehydrogenase in the central nervous system of the dog (1951) (173)
The character of the muscarinic receptors in different regions of the rat brain (1980) (171)
The secretion of potassium in saliva (1956) (169)
Physiology of the Salivary Glands (2015) (167)
Ontogeny of muscarinic receptors in rat brain (1980) (138)
The proton relaxation of benzyl alcohol in erythrocyte membranes. (1968) (136)
Large-scale purification and characterization of dihydrofolate reductase from a methotrexate-resistant strain of Lactobacillus casei. (1976) (129)
The metabolism of tritiated folic acid in man. (1961) (117)
THE BINDING OF [3H]‐PROPYLBENZILYLCHOLINE MUSTARD BY LONGITUDINAL MUSCLE STRIPS FROM GUINEA‐PIG SMALL INTESTINE (1974) (112)
Kinetics of complex formation between human carbonic anhydrases and aromatic sulfonamides. (1970) (104)
The uptake of isoprenaline and noradrenaline by the perfused rat heart. (1966) (102)
The use of transferred nuclear Overhauser effects in the study of the conformations of small molecules bound to proteins (1979) (102)
The binding of antagonists to brain muscarinic receptors. (1978) (100)
Gastrointestinal absorption and excretion of Mg 28 in man. (1960) (87)
Binding of coenzyme analogues to Lactobacillus casei dihydrofolate reductase: binary and ternary complexes. (1980) (82)
The membrane resting and action potentials of the cat auricle (1953) (79)
Two populations of binding sites for muscarinic antagonists in the rat heart. (1981) (79)
31P NMR studies of NADPH and NADP+ binding to L. casei dihydrofolate reductase (1975) (76)
Nuclear magnetic resonance studies of the binding of trimethoprim to dihydrofolate reductase. (1979) (76)
Kinetic aspects of structure─activity relations: the binding of sulphonamides by carbonic anhydrase (1976) (73)
Influence of pH on the kinetics of complex formation between aromatic sulfonamides and human carbonic anhydrase. (1970) (66)
Binding of agonists and antagonists to muscarinic receptors. (1976) (63)
Goals and purposes of higher education in the 21st century (1996) (63)
Proton nuclear magnetic resonance saturation transfer studies of coenzyme binding to Lactobacillus casei dihydrofolate reductase. (1980) (58)
19 Fnuclear magnetic resonance studies of ligand binding to 3-fluorotyrosine-and 6-fluorotryptophan-containing dihydrofolate reductase from Lactobacillus casei. (1977) (58)
The drug‐receptor complex (1966) (57)
Changes in the Permeability of the Salivary Gland Caused by Sympathetic Stimulation and by Catecholamines (1962) (57)
Receptor mechanisms. (1970) (54)
The secretion of non-electrolytes in the parotid saliva. (1956) (53)
Relaxation of Anaesthetics in the Presence of Cyto-membranes (1968) (52)
The conformation of acetylcholine and related compounds in aqueous solution as studied by nuclear magnetic resonance spectroscopy. (1972) (49)
The binding of benzyl alcohol to erythrocyte membranes. (1970) (48)
The role of ionic interaction at the muscarinic receptor. (1965) (48)
The location of cholinesterase in the central nervous system. (1952) (47)
The specificity of brain choline acetylase. (1956) (47)
Negative cooperativity between folinic acid and coenzyme in their binding to Lactobacillus casei dihydrofolate reductase. (1981) (45)
Conformational changes and drug action. (1981) (45)
Sulphonamide complexes of human carbonic anhydrases. Ultraviolet difference spectroscopy. (1970) (45)
Correlation Between the Binding Properties and Pharmacological Responses of Muscarinic Receptors (1978) (44)
Absorption of folic acid from the small intestine of the rat. (1962) (43)
Ligand-binding propeties of the muscarinic acetylcholine receptor in mouse neuroblastoma cells. (1978) (42)
Oxygen consumption and blood flow in the submaxillary gland of the dog. (1959) (42)
Pirenzepine--a ligand with original binding properties to muscarinic receptors. (1980) (42)
TECHNIQUES FOR STIMULATING THE AURICULO-TEMPORAL NERVE AND RECORDING THE FLOW OF SALIVA. (1964) (41)
The charge state of trimethoprim bound to Lactobacillus casei dihydrofolate reductase (1981) (40)
Topics in Molecular Pharmacology (1982) (40)
Investigation of the mechanism of ligand binding with cobalt(II) human carbonic anhydrase by 1 H and 19 F nuclear magnetic resonance spectroscopy. (1971) (40)
Preparation of selectively deuterated aromatic amino acids for use in 1H NMR studies of proteins. (1976) (39)
Occupancy of muscarinic acetylcholine receptors stimulates a guanylate cyclase in neuroblastoma cells. (1977) (38)
Cooperativity in ligand binding to dihydrofolate reductase. (1978) (36)
1H and 31P NMR characterization of two conformations of the trimethoprim-NADP+-dihydrofolate reductase complex. (1981) (36)
Conformational study of some component peptides of pentagastrin (1972) (36)
Phosphorus-31 nuclear magnetic resonance studies of the binding of oxidized coenzymes to Lactobacillus casei dihydrofolate reductase. (1980) (35)
Modulation of the binding properties of muscarinic receptors: evidence for receptor-effector coupling. (1980) (35)
A nuclear magnetic resonance study of nicotinamide adenine dinucleotide phosphate binding to Lactobacillus casei dihydrofolate reductase. (1975) (35)
A theoretical treatment of glucose reabsorption in the kidney. (1956) (34)
Direct observation by NMR of two coexisting conformations of an enzyme–ligand complex in solution (1981) (33)
Use of transferred nuclear Overhauser effect measurements to compare binding of coenzyme analogues to dihydrofolate reductase. (1983) (33)
Hydrogen-1, carbon-13, and phosphorus-31 nuclear magnetic resonance studies of the dihydrofolate reductase-nicotinamide adenine dinucleotide phosphate-folate complex: characterization of three coexisting conformational states. (1982) (32)
The role of the salivary duct system in the formation of the saliva. (1958) (32)
Nuclear magnetic resonance studies of the binding of substrate analogs and coenzyme to dihydrofolate reductase from Lactobacillus casei. (1974) (31)
Molecular graphics and drug design (1986) (31)
Kinetics of carbonic anhydrase-inhibitor complex formation. a comparison of anion- and sulfonamide-binding mechanisms. (1971) (31)
Effects of coenzyme analogues on the binding of p-aminobenzoyl-L-glutamate and 2,4-diaminopyrimidine to Lactobacillus casei dihydrofolate reductase. (1980) (29)
Conformational studies of oxytocin and lysine vasopressin in aqueous solution using high resolution NMR spectroscopy. (1971) (29)
GADDUM'S PHARMACOLOGY (1972) (29)
The inhibition of cholinesterases by alkyl-phosphates and alkylphenolphosphates. (1951) (29)
Histidine residues of Lactobacillus casei dihydrofolate reductase: paramagnetic relaxation and deuterium-exchange studies and partial assignments. (1980) (28)
Interactions of muscarinic receptors with guanine nucleotides and adenylate cyclase (1981) (28)
Proton nuclear magnetic resonance studies of the effects of ligand binding on tryptophan residues of selectively deuterated dihydrofolate reductase from Lactobacillus casei. (1980) (28)
Trimethoprim binding to bacterial and mammalian dihydrofolate reductase: a comparison by proton and carbon-13 nuclear magnetic resonance. (1983) (28)
Nuclear Magnetic Resonance in Biochemistry: Applications to Enzyme Systems (1974) (27)
Synaptic Physiology (1964) (26)
Unequivocal assignments of NH proton magnetic resonance bands in oxytocin using 2H‐ and 15N‐substituted molecules (1974) (26)
Competitive binding studies with multiple sites. Effects arising from depletion of the free radioligand. (1980) (25)
Growing up with science : developing early understanding of science (1997) (24)
Effects of coenzyme binding on histidine residues of Lactobacillus casei dihydrofolate reductase. (1981) (24)
A nuclear magnetic resonance study of the degradation of penicillin G in acidic solution (1979) (23)
Labelling of cholinergic receptors in subcellular fractions from rat cerebral cortex. (1972) (23)
The secretion of iodide in saliva. (1957) (22)
The mechanism of action of anticholinesterase drugs. (1949) (22)
A nuclear magnetic resonance study of the interaction between vanomycin and acetyl-D-alanyl-D-alanine in aqueous solution. (1975) (21)
Hydrogen-1 nuclear magnetic resonance study of the complexes of two diastereoisomers of folinic acid with dihydrofolate reductase. (1981) (21)
Investigation of a hapten-antibody complex by nuclear magnetic resonance. (1967) (21)
Application of analogue computer to measurement of intestinal absorption rates with tracers. (1961) (20)
Photo-CIDNP studies of the influence of ligand binding on the surface accessibility of aromatic residues in dihydrofolate reductase. (1980) (20)
Muscarinic receptor subclasses: evidence from binding studies. (1983) (20)
Solubilisation and molecular characterisation of muscarinic acetylcholine receptors. (1983) (19)
The physiological ultrastructure of cell membranes. (1957) (19)
The sites of transfer of sodium, potassium, and iodide in the parotid duct system of the dog. (1959) (19)
The use of saturation transfer NMR experiments to monitor the conformational selection accompanying ligand—protein interactions (1980) (19)
13C NMR evidence for three slowly interconverting conformations of the dihydrofolate reductase-NADP+-folate complex. (1981) (18)
Pharmacological actions of tetraethylpyrophosphate and hexaethyltetraphosphate. (1949) (18)
The background of the muscarinic system. (1995) (18)
The turnover of fluid in the dog's pleural cavity. (1958) (17)
The osmotic work of salivary secretion in the dog. (1955) (17)
Methods for studying the reflex activity of the frog's spinal cord. (1954) (17)
Development of ionic conductances in neurons of neurons of the inferior olive in the rat: an in vitro study (1988) (17)
Cutaneous and systemic reactions to human plasma. (1960) (16)
Physiological Effects of Alkyl Polyphosphates (1947) (15)
Intestinal Absorption of Tritium-Labelled Folic Acid in Idiopathic Steatorrhea: Effect of a Gluten-Free Diet (1963) (14)
The structure and function of cell membranes. (1962) (14)
The binding properties of muscarinic receptors in the brain of the frog (R. temporaria) (1980) (14)
Physiology of the salivary glands, by A.S.V. Burgen and N.G. Emmelin. (1961) (14)
Urinary excretion of phosphatases in man. (1947) (14)
A structure-activity study by nuclear magnetic resonance of peptide interactions with vancomycin. (1975) (13)
The effects of agonists on the components of the cardiac muscarinic receptor (1987) (13)
The disposal of tritiated folic acid injected intravenously in man. (1961) (12)
The Skin Lesions of Monocytic Leukaemia (1947) (12)
SYMPOSIUM ON NEUROSECRETION (1959) (12)
Drug receptors. (1979) (11)
Spin-lattice relaxation of methyl protons in some compounds of biological interest. (1969) (11)
The comparative activity of arecoline and arecoline N‐metho salt (1964) (10)
The secretion of lithium in saliva. (1958) (10)
Simplified Method for Estimation of Chloroform in Blood (1948) (9)
Tetra-ethylpyrophosphate in myasthenia gravis. (1948) (9)
The assay of anticholinesterase drugs by the chromodacryorrhoea response in rats. (1949) (9)
Regulation of Acetylcholine Receptors (1982) (9)
Multiple Classes of Muscarinic Receptor Binding Sites in the Brain (1979) (9)
Influx sites in the duct system of the dog parotid gland (1962) (8)
The effect of changes in the rate of flow of the saliva on the concentration of iodide in parotid saliva (1962) (8)
The specificity of drug receptors. An immunochemical model for cholinergic receptors. (1969) (8)
Ab initio molecular orbital calculations of electron distribution in tetramethylammonium ion. (1983) (8)
History and Basic Properties of the Muscarinic Cholinergic Receptor (1989) (8)
KINETIC METHODS FOR THE STUDY OF SALIVARY SECRETIONS; THEIR SCOPE LIMITATIONS. (1964) (8)
THE SECRETION OF LITHIUM IN SALIVA (1958) (7)
Receptor subunits and complexes (1992) (7)
Pharmacological Methods (1971) (7)
The idea of progress (1997) (7)
The effects of modification with N-bromosuccinimide on the binding of ligands to dihydrofolate reductase. (1980) (6)
Formation of lodinated Protein in Saliva (1962) (6)
On the Mechanism of Binding Choline Derivatives to an Anticholine Antibody (1968) (5)
Some processes concerned with the secretion of sodium, bromide and chloride in saliva (1963) (5)
THE PHARMACOLOGY OF THE METHYL AND BENZYL ESTERS OF γ‐CROTONIC BETAINE (γ‐CARBOXYALLYLTRIMETHYL‐AMMONIUM CHLORIDE) (1949) (5)
The action of alloxan and related compounds on alkaline phosphatase. (1947) (5)
Proceedings: Two populations of acetylcholine receptors in guinea-pig ileum. (1974) (4)
Infusion of Non-Autologous Plasma (1963) (4)
A method for measuring the turnover of fluid in the pleural and other serous cavities. (1958) (4)
Academia Europaea: Origin and Early Days (2009) (4)
The structural features determining the affinity of haptens for an antibody binding acetylcholine. (1969) (4)
St Anthony's gift (2003) (3)
Quantitative studies of procaine metabolism in the cat. (1948) (3)
Symposium on membrane transport. The effect of drugs on membrane transport. (1967) (3)
Ionic perturbation of agonist binding to brain muscarinic receptors [proceedings]. (1979) (3)
Water solute and cell exchanges in the dog's pleural fluid. (1955) (2)
The binding of (3H)-propylbenzilycholine mustard by longitudinal muscle strips from guinea-pig small intestine. (1974) (2)
Central and sensory transmission. (1954) (2)
Information flow in the nervous system (1993) (2)
An explosive story (2004) (2)
INFUSION OF NON-AUTOLOGOUS PLASMA. EFFECTS OF CHLORPHENIRAMINE, PREDNISOLONE, AND ADRENALINE. (1963) (2)
“Binding States” of Muscarinic Receptors (1981) (2)
Recent Advances in the Pharmacology of Toxins (1965) (2)
Interactions of peptides derived from the C-fragment of beta-lipotropin with brain opiate receptors [proceedings]. (1976) (2)
Exact numbers (2000) (2)
Muscarinic receptors: ionic perturbation of the binding properties [proceedings]. (1977) (2)
INTESTINAL ABSORPTION OF TRITUM-LABELLED FOLIC ACID IN IDIOPATHIC STEATORRHEA: EFFECT OF A GLUTENFREE DIET. (1963) (2)
François Magendie and the New Science of Drugs (1996) (1)
Two Interconverting Conformers of a Drug-Receptor Complex: The Lactobacillus Casei Dihydrofolate Reductase-NADP+ - Trimethoprim Complex (1983) (1)
Concepts in the primary science curriculum (1997) (1)
Ca 21 -independent inhibition of inositol trisphosphate receptors by calmodulin: Redistribution of calmodulin as a possible means of regulating Ca 21 mobilization (cerebellumyscintillation proximity assay) (1997) (1)
Anaesthetics and cell membranes (2004) (1)
Targets of drug action. (2000) (1)
Conformational Studies on Hormonal Peptides Using Nuclear Magnetic Resonance Spectroscopy (1974) (1)
Comparison of Effectiveness of Autologous and Nonautologous Plasma in Oligemic Shock in Dogs (1962) (1)
Calcium and Excitable Cells [Abridged] (1968) (1)
The United Kingdom and the reconstruction of German science: the rebirth of the Kaiser-Wilhelm-Gesellschaft (2001) (1)
Some considerations of receptor specificity. (1989) (1)
Chapter 13: Evolution and acetylcholine receptors (1993) (1)
Formation of iodinated protein in saliva. (1962) (1)
The theory, methods and relevance of muscarinic receptor binding studies. (1982) (1)
Frank Campbell MacIntosh, 24 December 1909 - 11 September 1992 (1994) (1)
Proceedings: Structure-activity relationships in the sulphonamide-carbonic anhydrase systems. (1974) (0)
Tobacco (2005) (0)
Book Review: Substances Producing Pain and Itch (1965) (0)
Virtual University? Educational Environments of the Future. Henk J. van der Molen (editor). Portland Press, London, 2001 (2001) (0)
Is this the new sociology of science? An editorial (2002) (0)
The state of quaternary ammonium ions in solution. (1969) (0)
The Nature of Complex Formation (2008) (0)
Editorial: what about the human genome? (2001) (0)
Proceedings: NMR studies of the binding of substrate analogues to L. casei dihydrofolate reductase. (1974) (0)
Co-operativity in ligand binding to dihydrofolate reductase [proceedings]. (1977) (0)
Introductory remarks (1980) (0)
Symposium on neurosecretion: introduction. (1959) (0)
Corrections - Hydrogen-1 Nuclear Resonance Study of the Complexes of Two Diastereoisomers of Folinic Acid with Dihydrofolate Reductase (1981) (0)
Evolution and acetylcholine receptors. (1993) (0)
Kinetic studies of coenzyme binding to L. casei dihydrofolate reductase [proceedings]. (1977) (0)
Research: The Possibilities of Medical Innovation (1974) (0)
1031 – AGONIST AND ANTAGONIST-BINDING PROPERTIES OF THE MUSCARINIC CHOLINERGIC RECEPTOR IN CEREBRAL CORTEX (1977) (0)
Book Review: Recent Advances in the Pharmacology of Toxins (1965) (0)
What does my left hand know? (1999) (0)
Conformational studies of some hormonal peptides in solution by using nuclear-magnetic-resonance spectroscopy. (1971) (0)
Bioassay, past and present (1990) (0)
31P and 1H n.m.r. studies of coenzyme binding to dihydrofolate reductase [proceedings]. (1977) (0)
The nature of complex formation. In: molecular properties of drug receptors. (1971) (0)
Summing Up (2021) (0)
Structure-activity relationships in the sulphonamide-carbonic anhydrase systemi NMR studies of the binding of substrate analogues to L. casei dihydrofolate reductase (2006) (0)
Symposium on Membrane Transport [Abridged] (1967) (0)
THE ACADEMIA EUROPAEA (2004) (0)
The nature of complex formation. In: Molecular properties of drug receptors. (1970) (0)
Nations, states and human rights (1993) (0)
The Formative Years of Young Scholars U. Teichler (Editor) Portland Press, 2006 ISBN-13-978-1-85578-1641 (2007) (0)
Cambridge Illustrated History of Medicine edited by Roy Porter Cambridge University Press, Cambridge, 1996 (400 pages). £24.95, hardback, ISBN 0-521-44211-7. (1997) (0)
Sir Arnold Burgen Interviewed by Anne Buttimer (2011) (0)
The binding of benzyl alcohol to erythrocyte membranes. (1970) (0)
The place of the basic medical sciences in clinical education. (1958) (0)
Demonstration and characterization of two co-existing conformations of an enzyme complex by n.m.r. (1980) (0)
Molecular Pharmacology (1971) (0)
No Gulf at Cambridge (1969) (0)
Hydrogen- 1, Carbon- 13, and Phosphorus-3 1 Nuclear Magnetic Resonance Studies of the Dihydrofolate Reductase-Nicotinamide Adenine Dinucleotide Phosphate-Folate Complex: Characterization of Three (1982) (0)
The Control of secretion : a Royal Society discussion held on 28 and 29 May 1981 (1982) (0)
The generation of receptor specificity. (1988) (0)
Sir Arnold Burgen FRS in interview with Lord Walton of Detchant Kt (2017) (0)
Denial Anaesthesia and Oxygen Lack (1942) (0)
The Right to Health (1972) (0)
Calcium and excitable cells. (1968) (0)
Interactions ofpeptides derived fromtheC-fragment of,B-lipotropin withbrain opiate receptors (1976) (0)
The action of acetylcholine and other drugs on the efflux of potassium and rubidium from smooth muscle of the guinea‐pig intestine (1997) (0)
The pharmacology of the methyl and benzyl esters of gamma-crotonic betaine (gamma-carboxyallyltrimethyl-ammonium chloride). (1949) (0)
The idea of progress: [... held at a conference in Gargellen, Austria in September 1994] (1997) (0)
Failure of nerve homogenates to catalyse the coupled breakdown of acetylcholine and energy-rich phosphate. (1949) (0)
Recent knowledge concerning the plasma proteins. (1946) (0)
Nuclear magnetic resonance studies of ligand binding to dihydrofolate reductase (1977) (0)
1023 – KINETICS OF SUBSTRATE, COENZYME AND INHIBITOR BINDING TO DIHYDROFOLATE REDUCTASE (1977) (0)
Shifting targets for our magic bullets. (1972) (0)
Calcium, an earthy messenger in cells (2002) (0)
1576 – THE MECHANISM OF MUSCARINIC RECEPTOR ACTION (1978) (0)
Effects of p-chloromercuribenzoate on muscarinic receptor binding in rat brain [proceedings]. (1980) (0)

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