Arnoud Sonnenberg
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Computer Science
Arnoud Sonnenberg's Degrees
- PhD Computer Science Delft University of Technology
- Masters Artificial Intelligence University of Amsterdam
- Bachelors Computer Science University of Amsterdam
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(Suggest an Edit or Addition)Arnoud Sonnenberg's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Function and interactions of integrins (2001) (1062)
- Laminin receptor on platelets is the integrin VLA-6 (1988) (700)
- Structure and function of hemidesmosomes: more than simple adhesion complexes. (1999) (602)
- Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner (2010) (589)
- Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion (1991) (567)
- Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components (1995) (509)
- Monoclonal antibodies against human milk‐fat globule membranes detecting differentiation antigens of the mammary gland and its tumors (1984) (503)
- Integrin–TGF‐β crosstalk in fibrosis, cancer and wound healing (2010) (468)
- Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin (2005) (465)
- Mouse egg integrin α6β1functions as a sperm receptor (1995) (445)
- Recombinant Vitronectin Is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self‐Renewal via αVβ5 Integrin (2008) (422)
- Epithelial detachment due to absence of hemidesmosomes in integrin β4 null mice (1996) (394)
- Structural and functional aspects of filamins. (2001) (372)
- A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody. (1987) (361)
- Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8 (1990) (359)
- Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice. (2011) (355)
- Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity (2005) (345)
- Stimulation‐Dependent Recycling of Integrin β1 Regulated by ARF6 and Rab11 (2004) (345)
- Integrins in regulation of tissue development and function (2003) (341)
- The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin (1990) (330)
- Mechanisms of integrin activation and trafficking. (2011) (329)
- Current insights into the formation and breakdown of hemidesmosomes. (2006) (326)
- The α6β4 Integrin Is a Receptor for both Laminin and Kalinin (1994) (323)
- Plakins in development and disease. (2007) (305)
- The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA–GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis (2002) (304)
- Cloning and sequence analysis of beta‐4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain. (1990) (291)
- Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1 (2006) (286)
- Recognition of the laminin E8 cell-binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubules (1990) (260)
- The Tetraspan Molecule Cd151, a Novel Constituent of Hemidesmosomes, Associates with the Integrin α6β4 and May Regulate the Spatial Organization of Hemidesmosomes (2000) (257)
- Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines. (1989) (255)
- Hemidesmosomes: roles in adhesion, signaling and human diseases. (1996) (243)
- Kidney failure in mice lacking the tetraspanin CD151 (2006) (243)
- The stomach in health and disease (2015) (239)
- Analysis of the interactions between BP180, BP230, plectin and the integrin α6β4 important for hemidesmosome assembly (2003) (229)
- Biology and function of hemidesmosomes. (1999) (222)
- Integrins control motile strategy through a Rho–cofilin pathway (2005) (215)
- Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins. (2000) (215)
- Distinct and overlapping ligand specificities of the alpha 3A beta 1 and alpha 6A beta 1 integrins: recognition of laminin isoforms. (1994) (212)
- Hemidesmosome Formation Is Initiated by the β4 Integrin Subunit, Requires Complex Formation of β4 and HD1/Plectin, and Involves a Direct Interaction between β4 and the Bullous Pemphigoid Antigen 180 (1998) (205)
- Glycoproteins V and Ib-IX form a noncovalent complex in the platelet membrane. (1992) (205)
- The alpha 6 beta 1 (VLA-6) and alpha 6 beta 4 protein complexes: tissue distribution and biochemical properties. (1990) (202)
- Integrins and their ligands. (1993) (198)
- Binding of Integrin α6β4 to Plectin Prevents Plectin Association with F-Actin but Does Not Interfere with Intermediate Filament Binding (1999) (198)
- Development of mouse mammary gland: identification of stages in differentiation of luminal and myoepithelial cells using monoclonal antibodies and polyvalent antiserum against keratin. (1986) (188)
- Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures. (1988) (184)
- P-selectin mediates Ca(2+)-dependent adhesion of activated platelets to many different types of leukocytes: detection by flow cytometry. (1992) (181)
- Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice. (1996) (180)
- Erratum: Integrins in regulation of tissue development and function. J Pathol; 200: 471–480 (2003) (177)
- 180-kD bullous pemphigoid antigen (BP180) is deficient in generalized atrophic benign epidermolysis bullosa. (1995) (174)
- TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton (2008) (165)
- Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin (2007) (163)
- Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily. (1989) (161)
- Induction of Cell Scattering by Expression of β1 Integrins in β1-Deficient Epithelial Cells Requires Activation of Members of the Rho Family of Gtpases and Downregulation of Cadherin and Catenin Function (1999) (161)
- Molecular cloning of the human α6 integrin subunit (1991) (156)
- Integrins: alternative splicing as a mechanism to regulate ligand binding and integrin signaling events (1999) (150)
- Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor. (1995) (149)
- Binding of soluble fibronectin to integrin α5β1 – link to focal adhesion redistribution and contractile shape (2008) (146)
- Deficiency of the integrin beta 4 subunit in junctional epidermolysis bullosa with pyloric atresia: consequences for hemidesmosome formation and adhesion properties. (1996) (145)
- Antibody to integrin α6 subunit specifically inhibits cell-binding to laminin fragment 8 (1990) (144)
- Unique and redundant functions of integrins in the epidermis (2010) (143)
- KASH-domain proteins in nuclear migration, anchorage and other processes (2006) (143)
- The Localization of Bullous Pemphigoid Antigen 180 (BP180) in Hemidesmosomes Is Mediated by Its Cytoplasmic Domain and Seems to be Regulated by the β4 Integrin Subunit (1997) (142)
- Skeletal myoblasts utilize a novel beta 1-series integrin and not alpha 6 beta 1 for binding to the E8 and T8 fragments of laminin. (1991) (142)
- The LIM-only Protein DRAL/FHL2 Binds to the Cytoplasmic Domain of Several α and β Integrin Chains and Is Recruited to Adhesion Complexes* (2000) (139)
- Biochemical characterization and tissue distribution of the A and B variants of the integrin alpha 6 subunit (1993) (137)
- Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo. (2002) (130)
- Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes. (2003) (129)
- The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins (2005) (126)
- Integrin α3β1 inhibits directional migration and wound re-epithelialization in the skin (2009) (126)
- Regulation of hemidesmosome disassembly by growth factor receptors. (2008) (123)
- Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interaction with isoforms of laminin. (1993) (121)
- Association of the tetraspanin CD151 with the laminin-binding integrinsα 3β1, α6β1, α6β4 and α7β1 in cells in culture and in vivo (2002) (121)
- Dual Stimulation of Ras/Mitogen-Activated Protein Kinase and Rhoa by Cell Adhesion to Fibronectin Supports Growth Factor–Stimulated Cell Cycle Progression (2000) (119)
- Multiple Functions of the Integrin α6β4 in Epidermal Homeostasis and Tumorigenesis (2006) (119)
- Cell–matrix adhesion of podocytes in physiology and disease (2013) (116)
- MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells. (2008) (115)
- Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus. (2003) (114)
- Formation of hemidesmosomes in cells of a transformed murine mammary tumor cell line and mechanisms involved in adherence of these cells to laminin and kalinin. (1993) (113)
- Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin β subunits (2002) (112)
- Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development. (1998) (112)
- The cAMP-Epac-Rap1 Pathway Regulates Cell Spreading and Cell Adhesion to Laminin-5 through the α3β1 Integrin but Not the α6β4 Integrin* (2004) (111)
- Transfection of the int‐1 mammary oncogene in cuboidal RAC mammary cell line results in morphological transformation and tumorigenicity. (1987) (110)
- Gain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome. (2012) (106)
- alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development. (2000) (106)
- A novel β1 integrin isoform produced by alternative splicing: unique expression in cardiac and skeletal muscle (1995) (103)
- Dynamics of the α6β4 Integrin in Keratinocytes (2002) (101)
- The opposing roles of laminin-binding integrins in cancer. (2017) (99)
- Variants of the alpha 6 beta 1 laminin receptor in early murine development: distribution, molecular cloning and chromosomal localization of the mouse integrin alpha 6 subunit. (1993) (98)
- Suppression of mouse melanoma metastasis by EA-1, a monoclonal antibody specific for alpha 6 integrins. (1993) (96)
- The Rac activator Tiam1 is required for α3β1-mediated laminin-5 deposition, cell spreading, and cell migration (2005) (94)
- The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin. (1994) (91)
- Filamin B Mediates ICAM-1-driven Leukocyte Transendothelial Migration* (2008) (91)
- Expression of the integrin alpha 6 beta 4 in peripheral nerves: localization in Schwann and perineural cells and different variants of the beta 4 subunit. (1994) (91)
- The 1//31 and c 6/ 1 Integrin Heterodimers Mediate Cell Attachment to Distinct Sites on Laminin (1990) (90)
- Demonstration of type II hemidesmosomes in a mammary gland epithelial cell line, BMGE-H. (1994) (89)
- The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression. (2001) (88)
- Keratinocytes display normal proliferation, survival and differentiation in conditional β4-integrin knockout mice (2005) (88)
- Structural and Functional Analysis of the Actin Binding Domain of Plectin Suggests Alternative Mechanisms for Binding to F-Actin and Integrin β4 (2003) (88)
- Distinct Roles of Talin and Kindlin in Regulating Integrin α5β1 Function and Trafficking (2012) (88)
- Identification and characterization of a novel antigen complex on mouse mammary tumor cells using a monoclonal antibody against platelet glycoprotein Ic. (1988) (86)
- The nanoscale geometrical maturation of focal adhesions controls stem cell differentiation and mechanotransduction. (2014) (84)
- Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption. (2007) (83)
- A minimal region on the integrin beta4 subunit that is critical to its localization in hemidesmosomes regulates the distribution of HD1/plectin in COS-7 cells. (1997) (81)
- Structural basis of the interaction between integrin α6β4 and plectin at the hemidesmosomes (2009) (79)
- Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis. (2006) (79)
- Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by α3β1, α6β1 and α6β4 integrins (2000) (79)
- Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis. (2012) (78)
- Isolation of α6β1 integrins from platelets and adherent cells by affinity chromatography on mouse laminin fragment E8 and human laminin pepsin fragment (1991) (78)
- Platelet adhesion to laminin: role of Ca2+ and Mg2+ ions, shear rate, and platelet membrane glycoproteins. (1992) (76)
- Blood pressure influences end-stage renal disease of Cd151 knockout mice. (2012) (74)
- Role of the bullous pemphigoid antigen 180 (BP180) in the assembly of hemidesmosomes and cell adhesion--reexpression of BP180 in generalized atrophic benign epidermolysis bullosa keratinocytes. (1998) (74)
- Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes. (1998) (74)
- Identification of novel interaction partners for the conserved membrane proximal region of α‐integrin cytoplasmic domains (1999) (73)
- Integrin alpha 6 beta 4 forms a complex with the cytoskeletal protein HD1 and induces its redistribution in transfected COS-7 cells. (1997) (70)
- Spatial and temporal expression of the β1D integrin during mouse development (1997) (70)
- Opposing roles of integrin alpha6Abeta1 and dystroglycan in laminin-mediated extracellular signal-regulated kinase activation. (2003) (70)
- Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis (2013) (68)
- Formation of hemidesmosome-like structures in the absence of ligand binding by the (alpha)6(beta)4 integrin requires binding of HD1/plectin to the cytoplasmic domain of the (beta)4 integrin subunit. (2000) (67)
- Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes (2008) (67)
- Secondary reduction of α7B integrin in laminin α2 deficient congenital muscular dystrophy supports an additional transmembrane link in skeletal muscle (1999) (67)
- Epithelial Development and Differentiation in the Mammary Gland Is Not Dependent on α3 or α6 Integrin Subunits (2001) (66)
- The interaction of plectin with actin: evidence for cross-linking of actin filaments by dimerization of the actin-binding domain of plectin. (2001) (66)
- Cre-loxP–mediated Inactivation of the α6A Integrin Splice Variant In Vivo: Evidence for a Specific Functional Role of α6A in Lymphocyte Migration but Not in Heart Development (1998) (64)
- Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells (2012) (64)
- Generalized atrophic benign epidermolysis bullosa. Either 180-kd bullous pemphigoid antigen or laminin-5 deficiency. (1996) (64)
- Control of mammary myoepithelial cell contractile function by α3β1 integrin signalling (2011) (63)
- The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin. (2004) (63)
- The mucin epiglycanin on TA3/Ha carcinoma cells prevents alpha 6 beta 4- mediated adhesion to laminin and kalinin and E-cadherin-mediated cell- cell interaction (1994) (63)
- Integrin α6β1-laminin interactions regulate early myotome formation in the mouse embryo (2006) (63)
- The A and B variants of the alpha 3 integrin subunit: tissue distribution and functional characterization. (1997) (62)
- Advances and perspectives of the architecture of hemidesmosomes: Lessons from structural biology (2009) (62)
- Two different mutations in the cytoplasmic domain of the integrin beta 4 subunit in nonlethal forms of epidermolysis bullosa prevent interaction of beta 4 with plectin. (2001) (61)
- Structural and functional aspects of ¢lamins (2001) (61)
- In vitro differentiation and progression of mouse mammary tumor cells. (1986) (60)
- EGF-induced MAPK Signaling Inhibits Hemidesmosome Formation through Phosphorylation of the Integrin β4* (2010) (60)
- Cleavage of the 6A Subunit Is Essential for Activation of the 6A1 Integrin by Phorbol 12-Myristate 13-Acetate (*) (1996) (58)
- Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival (2013) (58)
- Nesprin-3: a versatile connector between the nucleus and the cytoskeleton. (2011) (58)
- Expression patterns of laminin receptor splice variants α6Aβ1 and α6Bβ1 suggest different roles in mouse development (1995) (56)
- Integrin αvβ3 Controls Activity and Oncogenic Potential of Primed c-Src (2007) (56)
- Expression of integrin alpha 6 beta 4 in junctional epidermolysis bullosa. (1992) (55)
- Hemidesmosomes modulate force generation via focal adhesions (2020) (55)
- The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain. (2007) (55)
- Specificity of binding of the plectin actin-binding domain to beta4 integrin. (2003) (54)
- The role of phosphorylation in activation of the alpha 6A beta 1 laminin receptor. (1993) (52)
- Sepsis lethality via exacerbated tissue infiltration and TLR-induced cytokine production by neutrophils is integrin α3β1-dependent. (2014) (51)
- Episialin ( MUC 1 ) Overexpression Inhibits Integrin-mediated Cell Adhesion to Extracellular Matrix Components (2002) (51)
- CLIC4 regulates cell adhesion and &bgr;1 integrin trafficking (2014) (50)
- Laminin α1 chain mediated reduction of laminin α2 chain deficient muscular dystrophy involves integrin α7β1 and dystroglycan (2006) (50)
- Epithelial development and differentiation in the mammary gland is not dependent on alpha 3 or alpha 6 integrin subunits. (2001) (50)
- Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish (2011) (48)
- Dynamics of the alpha6beta4 integrin in keratinocytes. (2002) (48)
- Dual Role of α6β4 Integrin in Epidermal Tumor Growth: Tumor-suppressive Versus Tumor-promoting Function (2007) (48)
- The subcellular distribution of the high molecular mass protein, HD1, is determined by the cytoplasmic domain of the integrin beta 4 subunit. (1997) (48)
- Interaction of filamin A with the integrin β7 cytoplasmic domain: role of alternative splicing and phosphorylation (2004) (47)
- Tetraspanin CD151 maintains vascular stability by balancing the forces of cell adhesion and cytoskeletal tension. (2011) (47)
- Epigenetic Regulation of Galectin-3 Expression by β1 Integrins Promotes Cell Adhesion and Migration* (2012) (47)
- The PDZ domain of TIP-2/GIPC interacts with the C-terminus of the integrin α5 and α6 subunits (2002) (46)
- Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly (2012) (44)
- Antibody to integrin alpha 6 subunit specifically inhibits cell-binding to laminin fragment 8. (1990) (44)
- The Structure of the Plakin Domain of Plectin Reveals a Non-canonical SH3 Domain Interacting with Its Fourth Spectrin Repeat* (2011) (44)
- Signaling events mediated by α3β1 integrin are essential for mammary tumorigenesis (2014) (43)
- An Alternatively Spliced Exon in the Extracellular Domain of the Human α6 Integrin Subunit-Functional Analysis of the α6 Integrin Variants (1995) (41)
- Crosstalk between Cell Adhesion Complexes in Regulation of Mechanotransduction (2020) (41)
- Expression of α7β1 Integrin Splicing Variants during Skeletal Muscle Regeneration (2002) (40)
- A novel beta 1 integrin isoform produced by alternative splicing: unique expression in cardiac and skeletal muscle. (1995) (39)
- α3β1 and α6β4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development (2000) (38)
- Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src. (2007) (38)
- Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides (2014) (38)
- Glomerular extracellular matrix components and integrins. (1998) (37)
- Mechanisms of integrin αVβ5 clustering in flat clathrin lattices (2018) (37)
- Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo. (2006) (36)
- Tyrosine phosphorylation of P-selectin in intact platelets and in a disulphide-linked complex with immunoprecipitated pp60c-src. (1994) (35)
- Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin α6β4 (2015) (35)
- Dual Role of alpha6beta4 integrin in epidermal tumor growth: tumor-suppressive versus tumor-promoting function. (2007) (35)
- The two phenylalanines in the GFFKR motif of the integrin alpha6A subunit are essential for heterodimerization. (1997) (35)
- Monoclonal Antibodies Against Human Milkfat Globule Membranes Detecting Differentiation Antigens of the Mammary Gland (1982) (34)
- Secondary reduction of alpha7B integrin in laminin alpha2 deficient congenital muscular dystrophy supports an additional transmembrane link in skeletal muscle. (1999) (34)
- Determination of proteinase 3—α1‐antitrypsin complexes in inflammatory fluids (1992) (34)
- Structural and functional analysis of the actin binding domain of plectin suggests alternative mechanisms for binding to F-actin and integrin beta4. (2003) (33)
- Knock-in of integrin β1D affects primary but not secondary myogenesis in mice (2003) (33)
- Integrin laminin receptor profile of pulmonary squamous cell and adenocarcinomas. (1998) (32)
- Oncogene expression during progression of mouse mammary tumor cells; activity of a proviral enhancer and the resulting expression of int‐2 is influenced by the state of differentiation. (1987) (32)
- The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy (2015) (30)
- Kindlin-1 Regulates Integrin Dynamics and Adhesion Turnover (2013) (30)
- Molecular cloning of the human alpha 6 integrin subunit. Alternative splicing of alpha 6 mRNA and chromosomal localization of the alpha 6 and beta 4 genes. (1991) (30)
- Structure of the Calx-beta domain of the integrin beta4 subunit: insights into function and cation-independent stability. (2009) (29)
- The unique cytoplasmic domain of the human integrin variant beta4E is produced by partial retention of intronic sequences. (1997) (29)
- Genomic Organization of the Mouse β1 Gene: Conservation of the β1D but not of the β1B and β1C Integrin Splice Variants (1996) (29)
- Determinants in the cytoplasmic domain of P-selectin required for sorting to secretory granules. (1998) (29)
- Integrins Uncouple Src-induced Morphological and Oncogenic Transformation* (2008) (29)
- BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin. (2010) (28)
- Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner (2010) (28)
- Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles. (2010) (28)
- The PDZ domain of TIP-2/GIPC interacts with the C-terminus of the integrin alpha5 and alpha6 subunits. (2002) (27)
- The Cytoplasmic Domain of α6A Integrin Subunit Is an in Vitro Substrate for Protein Kinase C (1995) (27)
- Identification of the cleavage sites in the alpha6A integrin subunit: structural requirements for cleavage and functional analysis of the uncleaved alpha6Abeta1 integrin. (1997) (27)
- Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan. (2006) (26)
- The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape* (2016) (26)
- Conditional Deletion of the Itgb4 Integrin Gene in Schwann Cells Leads to Delayed Peripheral Nerve Regeneration (2008) (26)
- Laminin receptors in the integrin family. (1992) (25)
- Molecular consequences of deletion of the cytoplasmic domain of bullous pemphigoid 180 in a patient with predominant features of epidermolysis bullosa simplex. (2004) (25)
- Expression of Integrin alpha6beta4 in Junctional Epidermolysis Bullosa. (1992) (24)
- Modeling and Experimental Validation of the Binary Complex of the Plectin Actin-binding Domain and the First Pair of Fibronectin Type III (FNIII) Domains of the β4 Integrin* (2005) (23)
- Expression of the integrin α 6 β 4 in peripheral nerves : localization in Schwann and perineural cells and different variants of the β 4 subunit (1996) (23)
- Hemidesmosomes: molecular organization and their importance for cell adhesion and disease. (2004) (23)
- Integrin alpha6 maintains the structural integrity of the kidney collecting system. (2017) (22)
- Proteolysis of classic anti‐neutrophil cytoplasmic autoantibodies (C‐ANCA) by neutrophil proteinase 3 (1995) (21)
- The laminin binding α3 and α6 integrins cooperate to promote epithelial cell adhesion and growth. (2019) (21)
- Spatial and temporal expression of the beta1D integrin during mouse development. (1997) (21)
- The Rac activator Tiam 1 is required for 3 1-mediated laminin-5 deposition , cell spreading , and cell migration (2005) (20)
- Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin (2019) (20)
- Opposing Roles of Integrin 6 A 1 and Dystroglycan in Laminin-mediated Extracellular Signal-regulated Kinase Activation (2003) (20)
- Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene. (1999) (19)
- Isolation of alpha 6 beta 1 integrins from platelets and adherent cells by affinity chromatography on mouse laminin fragment E8 and human laminin pepsin fragment. (1991) (19)
- Kindlin-1 mutant zebrafish as an in vivo model system to study adhesion mechanisms in the epidermis. (2013) (19)
- Tetraspanin CD151 and integrin α3β1 contribute to the stabilization of integrin α6β4-containing cell-matrix adhesions (2019) (19)
- Autoantibodies to the laminin P1 fragment in HgCl2-induced membranous glomerulopathy. (1995) (19)
- Apical and basal Forssman antigen in MDCK II cells: a morphological and quantitative study. (1991) (19)
- Knock-in of integrin beta 1D affects primary but not secondary myogenesis in mice. (2003) (19)
- Integrin Recognition of Different Cell-binding Fragments of Laminin (P1, E3, E8) and Evidence that c 6fll But Not 6fl4 Functions as a Major Receptor for Fragment E8 (2002) (19)
- Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt (2015) (18)
- Implications of intragenic marker homozygosity and haplotype sharing in a rare autosomal recessive disorder: the example of the collagen type XVII (COL17A1) locus in generalised atrophic benign epidermolysis bullosa (1997) (18)
- The rod domain is not essential for the function of plectin in maintaining tissue integrity (2015) (18)
- Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins (2019) (17)
- Distribution of extracellular and cytoplasmic domains of the α3 and α6 integrin subunits in solid tumors (1995) (17)
- Biochemical Characterization and Tissue Distribution of the A and B Variants of the Integrin or 6 Subunit (2002) (17)
- Distribution of laminin variants and their integrin receptors in human secondary lymphoid tissue. Colocalization suggests that the alpha 6 beta 4-integrin is a receptor for laminin-5 in lymphoid follicles. (1996) (16)
- The regulation of expression of mouse mammary tumor virus DNA by steroid hormones and growth factors. (1989) (16)
- The nesprin-cytoskeleton interface probed directly on single nuclei is a mechanically rich system (2017) (16)
- Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of Cd151 (2013) (16)
- Expression of integrin α6β4 in functional epidermolysis bullosa (1992) (15)
- Monoclonal antibodies detecting different epitopes on the Forssman glycolipid hapten. (1986) (15)
- Genomic Organization of the Human a3 Integrin Subunit Gene (1998) (15)
- Truncated Type XVII Collagen Expression in a Patient with Non-Herlitz Junctional Epidermolysis Bullosa Caused by a Homozygous Splice-Site Mutation (2001) (15)
- Cell phenotypes and differentiative transitions in mouse submandibular salivary gland defined with monoclonal antibodies to mammary epithelial cells. (1994) (15)
- Expression of alpha7beta1 integrin splicing variants during skeletal muscle regeneration. (2002) (15)
- Antiplectin autoantibodies in subepidermal blistering diseases (2009) (14)
- Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration: Integrin/integrin antagonism regulates collective cell behaviour. (2020) (14)
- Cleavage of the alpha6A subunit is essential for activation of the alpha6Abeta1 integrin by phorbol 12-myristate 13-acetate. (1996) (14)
- Distinct and Overlapping Ligand Specificities of the a3Af 1 and a6Aj31 Integrins: Recognition of Laminin Isoforms (2003) (14)
- Expression patterns of laminin receptor splice variants alpha 6A beta 1 and alpha 6B beta 1 suggest different roles in mouse development. (1995) (14)
- The relation of 29 kD C‐ANCA antigen to proteinase 3 (1990) (13)
- Epithelial development and differentiation in the mammary gland is not dependent on the laminin receptors, alpha 6, alpha 3 and beta 4 integrin. (2001) (13)
- Formation of hemidesmosome-like structures in the absence of ligand binding by the α 6 β 4 integrin requires binding of HD 1 / plectin to the cytoplasmic domain of the β 4 integrin subunit (13)
- An alternatively spliced exon in the extracellular domain of the human alpha 6 integrin subunit--functional analysis of the alpha 6 integrin variants. (1995) (13)
- GENERALIZED ATROPHIC BENIGN EPIDERMOLYSIS-BULLOSA - EITHER 180-KD BULLOUS PEMPHIGOID ANTIGEN (BP180) OR LAMININ-5 IS DEFICIENT (1995) (13)
- Laminin-121--recombinant expression and interactions with integrins. (2010) (13)
- Reverse proteomic antibody screening identifies anti adhesive VHH targeting VLA-3. (2009) (12)
- Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential (2011) (12)
- MAPK uncouples cell cycle progression from cell spreading and cytoskeletal organization in cycling cells (2012) (12)
- Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo (2019) (11)
- Carbonic Anhydrase 5 Regulates Acid-Base Homeostasis in Zebrafish (2012) (11)
- CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease (2016) (11)
- The role of the cytoplasmic domain of alpha 6 integrin in the assembly and function of alpha 6 beta 1 and alpha 6 beta 4. (1996) (11)
- A novel specificity of anticytoplasmic autoantibodies directed against eosinophil peroxidase (1993) (11)
- Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. (2018) (10)
- Differentiation-dependent expression of provirus-activated int-1 oncogene in clonal cell lines derived from a mouse mammary tumor. (1990) (10)
- Defects in adhesion and migration, but not in proliferation and differentiation, of embryonic stem cells upon replacement of integrin subunit beta1A by beta1D. (2000) (10)
- 180-KD BULLOUS PEMPHIGOID ANTIGEN (BPAG2) IS NOT EXPRESSED IN GENERALIZED ATROPHIC BENIGN EPIDERMOLYSIS-BULLOSA (1994) (10)
- Regulation of hemidesmosome dynamics and cell signaling by integrin α6β4. (2021) (10)
- Laminin-binding integrins are essential for the maintenance of functional mammary secretory epithelium in lactation (2020) (10)
- Transforming growth factor-beta represses transcription of the mouse mammary tumour virus DNA in cultured mouse mammary cells. (1990) (10)
- Molecular characterization of a membrane protein by a simple immunobinding procedure with monoclonal antibodies. (1984) (9)
- Ultrastructural localization of integrin subunits alpha3 and alpha6 in capillarized sinusoids of the human cirrhotic liver. (2004) (9)
- Antigenic modulation of mammary tumour virus envelope antigen or GR thymic lymphoma cells in relation to expressions of H-2, TL cell-surface antigens and THY1. (1980) (9)
- The regulation of MacMARCKS expression by integrin β3 (2007) (9)
- Expression of Integrin a64 in Junctional Epidermolysis Bullosa (1992) (8)
- Activation States of Integrins (1997) (8)
- The Hemidesmosomal Protein Bullous Pemphigoid Antigen 1 and the Integrin β4 Subunit Bind to ERBIN (2001) (8)
- ANCA related antigens (1990) (7)
- Laminin-binding integrins are essential for the maintenance of functional mammary secretory epithelium in lactation. (2020) (7)
- Changes in Antigen Patterns During Development of the Mouse Mammary Gland: Implications for Tumorigenesis (1987) (7)
- Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin. (2005) (7)
- Spatial and Temporal Expression of the b1D Integrin During Mouse Development (1997) (6)
- Integrin α3β1 is a key regulator of several pro-tumorigenic pathways during skin carcinogenesis. (2020) (6)
- Distribution of extracellular and cytoplasmic domains of the alpha 3 and alpha 6 integrin subunits in solid tumors. (1995) (6)
- PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736 (2015) (6)
- Investigation into the mechanism regulating MRP localization. (2008) (6)
- Interaction of BP180 and α6β4 (1999) (6)
- Comparative interactomics analysis reveals potential regulators of α6β4 distribution in keratinocytes (2020) (5)
- Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis (2020) (5)
- Determination of proteinase 3-alpha 1-antitrypsin complexes in inflammatory fluids. (1992) (5)
- The cytoplasmic domain of alpha 6A integrin subunit is an in vitro substrate for protein kinase C. (1995) (5)
- Genomic organization of the human alpha 3 integrin subunit gene. (1998) (4)
- The regulation of MacMARCKS expression by integrin beta3. (2007) (4)
- Partial rescue of epithelial phenotype in integrin β 4 null mice by a keratin-5 promoter driven human integrin β 4 transgene (1999) (4)
- Interaction of BP180 and alpha6beta4. (1999) (4)
- Experimental Results on Invasiveness of Mouse Mammary Cells: Clinical Implications? (1986) (4)
- Tumor promoter binding to rat mammary cell cultures: role of receptors in the inhibition of dome formation. (1983) (4)
- Ultrastructural localization of integrin subunits α 3 and α 6 in capillarized sinusoids of the human cirrhotic liver (2004) (3)
- Comparative interactomics analysis reveals potential regulators of α6β4 distribution in keratinocytes. (2020) (3)
- LAMININ-EPITOPE SPECIFICITY OF MONOCLONAL AUTOANTIBODIES IN HGC12-INDUCED NEPHROPATHY (1990) (3)
- Genomic organization of the mouse beta 1 gene: conservation of the beta 1D but not of the beta 1B and beta 1C integrin splice variants. (1996) (3)
- Role of the gene on trisomic and pentasomic chromosome 13 in murine mammary tumorigenesis. (1993) (3)
- EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines (2021) (3)
- Molecular determinants of αVβ5 localization in flat clathrin lattices – role of αVβ5 in cell adhesion and proliferation (2022) (3)
- Identification of the cleavage sites in the a 6A integrin subunit : structural requirements for cleavage and functional analysis of the uncleaved a 6A b 1 integrin (1997) (3)
- Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins (2019) (3)
- 180-kd bullous pemphigoid antigen (BP180) is deficient in a patient with generalized atrophic benign epidermolysis-bullosa (1994) (3)
- and platelet membrane glycoproteins Platelet adhesion to laminin: role of Ca2+ and Mg2+ ions, shear rate, (2011) (2)
- Integrin Special Issue (2009) (2)
- Cell-to-cell contact and extracellular matrix. Editorial overview. (2011) (2)
- Structural basis of the interaction between integrin β4 and plectin at the hemidesmosomes (2008) (1)
- PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins (2022) (1)
- Structural basis of integrin α6β4 interaction with the bullous pemphigoid antigen BP230 in hemidesmosomes (2018) (1)
- Immunological Markers in the Study of the Development of the Mouse Mammary Gland and Its Tumors (1988) (1)
- Fibre Reinforced Polymer Composite Short Span Bridges: Are they viable? (1997) (1)
- The laminin-binding integrins regulate nuclear factor kappa-β-dependent epithelial cell polarity and inflammation. (2021) (1)
- Phenotypic reversion of junctional epidermolysis bullosa associated with pyloric atresia Role of the alpha-6-beta-4 integrin in the assembly of hemidesmosomes and adhesion (1997) (1)
- Structure of the plakin domain of plectin: implications for the mechanical properties of plakins (2016) (0)
- tetraspanin CD151 in primary endothelial cells MT1-MMP collagenolytic activity is regulated through association with (2008) (0)
- Hemidesmosome Formation Is Initiated by the (cid:98) 4 Integrin Subunit, Requires Complex Formation of (cid:98) 4 and HD1/Plectin, and Involves a Direct Interaction between (cid:98) 4 and the Bullous Pemphigoid Antigen 180 (1998) (0)
- Architecture of hemidesmosomes (2016) (0)
- Integrins in regulation of tissue development and function. (2003) (0)
- The regulation of Rho and Src signaling by integrins (2008) (0)
- Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin (cid:2) subunits (2002) (0)
- Identification of domains within the tail of the β4 integrin subunit which coordinates the assembly of hemidesmosomes (1998) (0)
- Biosynthesis and function of base J, a new base in the nuclear DNA of kinetoplastid parasites (1993) (0)
- Analysis of the interaction between desmosomal proteins: Desmoplakin and Plakophilins-1/2 (2012) (0)
- Integrin-mediated regulation of Rho GTPases in control of tumor invasion (2006) (0)
- Mapping of mutual binding sites in the hemidesmosomal proteins BPAG1e and α6ß4 integrin (2014) (0)
- Correction (2005) (0)
- Mapping of the integrin α6β4 binding site in the N-terminal region of the bullous pemphigoid antigen 1, BPAG1e (2012) (0)
- MAPK uncouples cell cycle progression from cell spreading and cytoskeletal organization in cycling cells (2012) (0)
- Dynamics of the 64 Integrin in Keratinocytes □ V (2002) (0)
- What does it take to be a collagen receptor? (2022) (0)
- The fibronectin-binding integrins (cid:2) 5 (cid:3) 1 and (cid:2) v (cid:3) 3 differentially modulate RhoA–GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis (2002) (0)
- Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo (2019) (0)
- MINIREVIEW Multiple Functions of the Integrin (cid:2) 6 (cid:3) 4 in Epidermal Homeostasis and Tumorigenesis (2006) (0)
- The role of the integrin alpha(6)beta(4) in call adhesion and formation of hemidesmosomes. (1996) (0)
- Cre- loxP –mediated Inactivation of the (cid:97) 6A Integrin Splice Variant In Vivo: Evidence for a Specific Functional Role of (cid:97) 6A in Lymphocyte Migration but Not in Heart Development (1998) (0)
- The « 6 / M ( VLA-6 ) and a 6 / J 4 protein complexes : tissue distribution and biochemical properties (2005) (0)
- Implications of intragenic marker homozygosity and haplotype sharing in generalized atrophic benign epidermolysis bullosa (GABEB) (1997) (0)
- A novel fll integrin isoform produced by alternative splicing : unique expression in cardiac and skeletal muscle (2003) (0)
- Structure of the second pair of fibronectin type III repeats of the integrin β4 (2011) (0)
- Cooperation between the Src oncogene and integrin alpha-v beta-3 in oncogenic transformation of epithelial cells (2003) (0)
- Erratum : (Journal of Cell Biology (May 9, 2005) 169:3 (515-526)) (2005) (0)
- MOUSE MAMMARY TUMOR CELL TYPES Cloning Efficiency of Cells in Soft Agar (2006) (0)
- Combination of DEER, SAXS, X-Ray crystallography and molecular modeling to obtain the structure of integrin ß4 domains (2014) (0)
- Electron beam vulcanization of elastomers (1984) (0)
- Mapping of mutual binding sites in the hemidesmosomal proteins integrin α6ß4 and BPAG1e (2015) (0)
- Running title: Regulation of MT1-MMP activity by tetraspanin CD151 Scientific Category: Hemostasis, Trombosis and Vascular Biology Abreviations: HUVEC: Human umbilical vein endothelial cells MLEC: Mouse lung endothelial cells FRET: Fluorescence Resonance Energy Transfer MMP: Matrix Metalloproteinase (2008) (0)
- CHARACTERIZATION OF THE MURINE CASEIN GENE FAMILY: EVOLUTION AND CHROMOSOMAL LOCALIZATION (1981) (0)
- Structural basis of the interaction between integrin a6b4 and the bullous pemphigoid antigen BP230 in hemidesmosomes (2019) (0)
- Intermediate filament associated proteins (2016) (0)
- Integrin a614 Forms a Complex with the Cytoskeletal Protein HD1 and Induces Its Redistribution in Transfected COS-7 Cells (0)
- A laminin receptor essential for development of epithelial tubules in the mouse kidney (1990) (0)
- University of Groningen Unusual variants of subepidermal autoimmune bullous diseases (2017) (0)
- Structure of a fragment of the integrin ß4 by hybrid methods: x-ray crystallography, small angle x-ray scattering and electron paramagnetic resonance spectroscopy (2014) (0)
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