Aron H. Lichtman
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(Suggest an Edit or Addition)Aron H. Lichtman's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase (2001) (1243)
- Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects (2008) (836)
- Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation (2011) (583)
- Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system (2010) (545)
- Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo (2009) (363)
- Reversible Inhibitors of Fatty Acid Amide Hydrolase That Promote Analgesia: Evidence for an Unprecedented Combination of Potency and Selectivity (2004) (332)
- Blockade of Endocannabinoid-Degrading Enzymes Attenuates Neuropathic Pain (2009) (309)
- Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. (2003) (298)
- Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia (2004) (298)
- Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement. (1996) (263)
- Evaluation of CB1 receptor knockout mice in the Morris water maze. (2002) (246)
- Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats (1995) (235)
- Spinal and supraspinal components of cannabinoid-induced antinociception. (1991) (234)
- Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. (2002) (228)
- Functional disassociation of the central and peripheral fatty acid amide signaling systems. (2004) (221)
- Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity (2017) (216)
- The endogenous cannabinoid system and its role in nociceptive behavior. (2004) (208)
- The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain (2018) (189)
- Increased Seizure Susceptibility and Proconvulsant Activity of Anandamide in Mice Lacking Fatty Acid Amide Hydrolase (2003) (186)
- Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality (2007) (182)
- SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats. (2000) (174)
- Δ9-Tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism (1996) (172)
- Inhibition of Fatty-Acid Amide Hydrolase Accelerates Acquisition and Extinction Rates in a Spatial Memory Task (2007) (171)
- Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay (2011) (170)
- Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory (2014) (165)
- Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain. (2017) (161)
- Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice. (2001) (151)
- Targeting Fatty Acid Amide Hydrolase (FAAH) to Treat Pain and Inflammation (2009) (150)
- Repeated Low-Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains Cannabinoid Receptor Type 1–Mediated Antinociceptive and Gastroprotective Effects (2013) (146)
- Cannabinoid tolerance and dependence. (2005) (144)
- Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice (2013) (142)
- Opposing actions of chronic Delta9-tetrahydrocannabinol and cannabinoid antagonists on hippocampal long-term potentiation. (2007) (142)
- Endocannabinoids Shape Accumbal Encoding of Cue-Motivated Behavior via CB1 Receptor Activation in the Ventral Tegmentum (2012) (141)
- Endocannabinoids in cognition and dependence. (2002) (136)
- Δ9-Tetrahydrocannbinol Accounts for the Antinociceptive, Hypothermic, and Cataleptic Effects of Marijuana in Mice (2005) (131)
- Disruption of CB1 receptor signaling impairs extinction of spatial memory in mice (2005) (129)
- The enzymatic inactivation of the fatty acid amide class of signaling lipids. (2002) (123)
- Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies (2017) (120)
- Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms. (2010) (119)
- A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects (2015) (118)
- Differential effects of Δ9-THC on spatial reference and working memory in mice (2001) (118)
- Hippocampal CB1 receptors mediate the memory impairing effects of Δ9-tetrahydrocannabinol (2009) (118)
- Cannabinoid Transmission and Pain Perception (1998) (117)
- In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects (2014) (115)
- The disruptive effects of the CB1 receptor antagonist rimonabant on extinction learning in mice are task-specific (2007) (112)
- Synergy between Enzyme Inhibitors of Fatty Acid Amide Hydrolase and Cyclooxygenase in Visceral Nociception (2009) (111)
- The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. (2013) (111)
- Regulation of Inflammatory Pain by Inhibition of Fatty Acid Amide Hydrolase (2010) (107)
- The Endogenous Cannabinoid System Modulates Nicotine Reward and Dependence (2008) (107)
- Cannabinoid-induced antinociception is mediated by a spinalα2-noradrenergic mechanism (1991) (106)
- Interactions between THC and cannabidiol in mouse models of cannabinoid activity (2006) (106)
- Novel bioactive metabolites of dipyrone (metamizol). (2012) (106)
- Inhibitors of Endocannabinoid-Metabolizing Enzymes Reduce Precipitated Withdrawal Responses in THC-Dependent Mice (2009) (105)
- Discovery of Prostamide F2α and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability (2012) (104)
- Blockade of Endocannabinoid Hydrolytic Enzymes Attenuates Precipitated Opioid Withdrawal Symptoms in Mice (2011) (102)
- The Selective Cannabinoid Antagonist SR 141716A Blocks Cannabinoid-Induced Antinociception in Rats (1997) (99)
- The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects (2011) (98)
- The fatty acid amide hydrolase (FAAH) inhibitor PF‐3845 acts in the nervous system to reverse LPS‐induced tactile allodynia in mice (2012) (95)
- The psychoactive plant cannabinoid, Δ9‐tetrahydrocannabinol, is antagonized by Δ8‐ and Δ9‐tetrahydrocannabivarin in mice in vivo (2007) (89)
- Inhibition of Monoacylglycerol Lipase Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Hemorrhages in Mice (2011) (88)
- Cannabinoid CB2 Receptors Regulate Central Sensitization and Pain Responses Associated with Osteoarthritis of the Knee Joint (2013) (85)
- Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. (2008) (81)
- Endocannabinoid Modulation of Scratching Response in an Acute Allergenic Model: A New Prospective Neural Therapeutic Target for Pruritus (2009) (81)
- Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse (2017) (80)
- FAAH−/− Mice Display Differential Tolerance, Dependence, and Cannabinoid Receptor Adaptation After Δ9-Tetrahydrocannabinol and Anandamide Administration (2010) (80)
- The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice (2013) (79)
- Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice (2011) (78)
- Effects of alpha 7 positive allosteric modulators in murine inflammatory and chronic neuropathic pain models (2013) (75)
- Marijuana Withdrawal Syndrome in the Animal Model (2002) (75)
- Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol. (2010) (74)
- Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action. (2015) (74)
- Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function (2015) (71)
- Exposure to Marijuana Smoke Impairs Memory Retrieval in Mice (2007) (71)
- Differential effects of delta 9-THC on spatial reference and working memory in mice. (2001) (71)
- Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. (1998) (71)
- Stout Guards of the Central Nervous System (2003) (70)
- The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or TRPV1 (2009) (68)
- Evaluation of fatty acid amides in the carrageenan-induced paw edema model (2008) (68)
- Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice (2015) (66)
- Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice. (2012) (64)
- Endocannabinoids: A Promising Impact for Traumatic Brain Injury (2017) (64)
- A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2‐arachidonoylglycerol with potential anti‐obesity effects (2013) (64)
- Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Antiwithdrawal Effects in Morphine-Dependent Mice (2013) (62)
- The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain (2016) (59)
- In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569 (2014) (59)
- Precipitated cannabinoid withdrawal is reversed by Δ9-tetrahydrocannabinol or clonidine (2001) (59)
- Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice. (2012) (59)
- Cats produce analgesia in rats on the tail-flick test: naltrexone sensitivity is determined by the nociceptive test stimulus (1990) (58)
- The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice (2017) (57)
- Tonic nociception in neonatal rats (1990) (55)
- The up-and-down method substantially reduces the number of animals required to determine antinociceptive ED50 values. (1998) (52)
- Food for thought: endocannabinoid modulation of lipogenesis. (2005) (50)
- Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature (1993) (50)
- Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception. (2009) (50)
- The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI‐101 prevents cisplatin‐induced nephrotoxicity (2016) (50)
- Combination of Rimonabant and Donepezil Prolongs Spatial Memory Duration (2007) (49)
- The pharmacological activity of inhalation exposure to marijuana smoke in mice. (2001) (48)
- SR 141716 (Rimonabant) precipitates withdrawal in marijuana-dependent mice (2006) (47)
- The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model (2016) (47)
- Pharmacological evaluation of aerosolized cannabinoids in mice. (2000) (46)
- Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy (2018) (45)
- Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics. (2011) (45)
- Differential endocannabinoid regulation of extinction in appetitive and aversive Barnes maze tasks. (2008) (45)
- Novel Insights on the Effect of Nicotine in a Murine Colitis Model (2013) (44)
- Fatty Acid Amide Hydrolase (–/–) Mice Exhibit an Increased Sensitivity to the Disruptive Effects of Anandamide or Oleamide in a Working Memory Water Maze Task (2006) (44)
- NIH 11082 produces anti-depressant-like activity in the mouse tail-suspension test through a delta-opioid receptor mechanism of action. (2007) (44)
- Cannabinoid-induced antinociception is mediated by a spinal alpha 2-noradrenergic mechanism. (1991) (42)
- Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models (2014) (42)
- Production and Actions of the Anandamide Metabolite Prostamide E2 in the Renal Medulla (2012) (41)
- Δ9-THC-induced cognitive deficits in mice are reversed by the GABAA antagonist bicuculline (2005) (41)
- Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler. (2002) (41)
- Δ8‐Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors (2012) (40)
- Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex (2016) (39)
- Endocannabinoid Overload (2010) (39)
- Disposition of cannabichromene, cannabidiol, and Δ⁹-tetrahydrocannabinol and its metabolites in mouse brain following marijuana inhalation determined by high-performance liquid chromatography-tandem mass spectrometry. (2010) (39)
- Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide (2013) (38)
- The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. (2013) (38)
- Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. (2007) (38)
- Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action. (2008) (38)
- Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice (2020) (37)
- Precipitated cannabinoid withdrawal is reversed by Delta(9)-tetrahydrocannabinol or clonidine. (2001) (37)
- The uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist memantine prolongs spatial memory in a rat delayed radial-arm maze memory task. (2007) (36)
- Diacylglycerol lipase β inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain (2016) (36)
- Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats (2014) (35)
- Inhibition of monoacylglycerol lipase reduces nicotine withdrawal (2015) (34)
- Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein (2017) (33)
- Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice (2016) (33)
- Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice (2015) (33)
- Evaluation of CB 1 Receptor Knockout Mice in the Morris Water Maze (2002) (32)
- Prolonged Monoacylglycerol Lipase Blockade Causes Equivalent Cannabinoid Receptor Type 1 Receptor–Mediated Adaptations in Fatty Acid Amide Hydrolase Wild-Type and Knockout Mice (2014) (32)
- Δ9-Tetrahydrocannabinol and Endocannabinoid Degradative Enzyme Inhibitors Attenuate Intracranial Self-Stimulation in Mice (2015) (32)
- CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action (2011) (32)
- Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays (2016) (32)
- Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice (2012) (31)
- The Endocannabinoid System: Role in Energy Regulation (2012) (31)
- Inhalation studies with drugs of abuse. (1997) (31)
- Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. (2013) (30)
- Opioid and nonopioid conditional analgesia: the role of spinal opioid, noradrenergic, and serotonergic systems. (1991) (30)
- The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators. (2019) (30)
- Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. (2015) (30)
- In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence (2017) (29)
- Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and β-arrestin 2 activity in the forebrain (2016) (29)
- Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. (2014) (29)
- N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice (2019) (29)
- Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity (2018) (28)
- Delta(9)-THC-induced cognitive deficits in mice are reversed by the GABA(A) antagonist bicuculline. (2005) (27)
- Inhalation exposure to volatilized opioids produces antinociception in mice. (1996) (27)
- Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus (2015) (27)
- Pharmacological effects of methamphetamine and other stimulants via inhalation exposure. (1999) (26)
- Combined Antiproliferative Effects of the Aminoalkylindole WIN55,212-2 and Radiation in Breast Cancer Cells (2014) (26)
- Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS (2018) (26)
- Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters (2014) (26)
- Marijuana dependence: not just smoke and mirrors. (2011) (26)
- Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN (2018) (26)
- Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task (2009) (25)
- Are CB1 receptor antagonists nootropic or cognitive impairing agents? (2009) (24)
- Acetylcodeine, an impurity of illicitly manufactured heroin, elicits convulsions, antinociception, and locomotor stimulation in mice. (2001) (24)
- Neuroscience. Stout guards of the central nervous system. (2003) (24)
- The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice (2017) (23)
- The cannabinoid CB(1) receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task. (2008) (23)
- Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (2011) (22)
- Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices (2016) (21)
- Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model (2017) (21)
- Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice (2015) (20)
- Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice (2012) (20)
- Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model (2017) (20)
- Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo. (2017) (19)
- Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system (2014) (18)
- Evaluation of cAMP involvement in cannabinoid-induced antinociception. (1995) (17)
- Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine (2007) (16)
- Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice. (2015) (15)
- ∆9-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory (2011) (15)
- Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids. (2016) (15)
- Determination of naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in mouse blood and tissue after inhalation exposure to 'buzz' smoke by HPLC/MS/MS. (2012) (15)
- Evaluation of different drug classes on transient sciatic nerve injury–depressed marble burying in mice (2018) (15)
- l-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice (2012) (15)
- The antinociceptive effects of intrathecally administered cannabinoids are influenced by lipophilicity (1992) (14)
- Comparison of escape and tail flick thresholds in the rat: A psychophysical analysis of morphine hypoalgesia (1990) (14)
- Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497 (2016) (14)
- Molecular Mechanism and Cannabinoid Pharmacology. (2020) (14)
- Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge (2015) (13)
- Inhibitory Control Deficits Associated with Upregulation of CB1R in the HIV-1 Tat Transgenic Mouse Model of Hand (2019) (13)
- alpha-Benzyl-N-methylphenethylamine (BNMPA), an impurity of illicit methamphetamine synthesis: pharmacological evaluation and interaction with methamphetamine. (1995) (12)
- Differential Tolerance to FTY720-Induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role of Sphingosine-1-Phosphate Receptor Adaptation (2018) (12)
- Investigation of left and right lateral fluid percussion injury in C57BL6/J mice: In vivo functional consequences (2017) (11)
- C57BL/6 substrain differences in formalin-induced pain-like behavioral responses (2020) (11)
- Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice (2017) (10)
- Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions. (2014) (10)
- Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine (2019) (10)
- Cannabinoid exposure during zebra finch sensorimotor vocal learning persistently alters expression of endocannabinoid signaling elements and acute agonist responsiveness (2011) (10)
- Relative importance of experience, social facilitation, and availability of milk in weaning of rats. (1989) (10)
- Role of Dopamine Type 1 Receptors and Dopamine- and cAMP-Regulated Phosphoprotein Mr 32 kDa in Δ9-Tetrahydrocannabinol–Mediated Induction of ΔFosB in the Mouse Forebrain (2015) (9)
- Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice (2019) (9)
- Evaluation of Agonist-antagonist Properties of Nitrogen Mustard and Cyano Derivatives of Δ8-Tetrahydrocannabinol (1996) (9)
- Neuronal nicotinic acetylcholine receptors mediate ∆9‐THC dependence: Mouse and human studies (2018) (8)
- Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids (2020) (8)
- Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague–Dawley rats (2019) (8)
- Stimulation of diuresis and natriuresis by renomedullary infusion of a dual inhibitor of fatty acid amide hydrolase and monoacylglycerol lipase. (2017) (8)
- Development of a high-performance liquid chromatography-tandem mass spectrometry method for the identification and quantification of CP-47,497, CP-47,497-C8 and JWH-250 in mouse brain. (2014) (7)
- Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats (2020) (7)
- Role of the endocannabinoid system in learning and memory (2005) (7)
- GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration (2021) (7)
- Pro-Leu-Gly-NH2 serves as a conditioned stimulus in the acquisition of conditioned tolerance. (1989) (7)
- Cannabis Dependence: Understanding the Pharmacology and Physiology of Cannabis Dependence (2006) (6)
- A FAAH-fetched approach to treat osteoarthritis pain (2011) (6)
- Acute tolerance to the cardiovascular effects of volatilized cocaine free base in rats. (1995) (6)
- Spinal action of cannabinoid-induced antinociception. (1990) (6)
- Δ8‐Tetrahydrocannabivarin has potent anti‐nicotine effects in several rodent models of nicotine dependence (2019) (6)
- Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice (2016) (5)
- Methysergide-induced nipple attachment depends on suckling experience in juvenile rats. (1989) (5)
- In vivo evaluation of the CB1 allosteric modulator LDK1258 reveals CB1-receptor independent behavioral effects (2019) (5)
- Protective effects of N-oleoylglycine in a mouse model of mild traumatic brain injury. (2020) (5)
- HPLC-MS-MS Determination of ZCZ-011, A Novel Pharmacological Tool for Investigation of the Cannabinoid Receptor in Mouse Brain Using Clean Screen FASt™ Column Extraction. (2015) (5)
- Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice (2020) (5)
- Ocular and Systemic Effects of WIN 55-212-2 in Normotensive Rabbits (2003) (4)
- N‐acylethanolamine‐hydrolysing acid amidase: A new potential target to treat paclitaxel‐induced neuropathy (2021) (4)
- Cannabinoids and Cancer Chemotherapy-Associated Adverse Effects. (2021) (4)
- Inhibition of monoacylglycerol lipase ( MAGL ) attenuates NSAID-induced gastric hemorrhages in mice (2011) (4)
- Peripheral serotonergic inhibition of suckling (1990) (4)
- Pharmacological potency and biodisposition of phencyclidine via inhalation exposure in mice. (1996) (4)
- Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in N-Oleoylglycine and N-Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators (2021) (4)
- Targeting FAAH and COX to Treat Visceral Pain (2008) (3)
- The CB1 Receptor Positive Allosteric Modulator, ZCZ011, Attenuates Naloxone-Precipitated Diarrhea and Weight Loss in Oxycodone-Dependent Mice. (2021) (3)
- Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus (2014) (3)
- Full FAAH inhibition combined with partial monoacylglycerol lipase inhibition: Augmented and sustained antinociceptive effects with reduced cannabimimetic side effects in mice (2015) (3)
- Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat (2021) (3)
- Preclinical investigation of the abused synthetic cannabinoid CP47,497 (2014) (3)
- N-Oleoylglycine and N-Oleoylalanine Do Not Modify Tolerance to Nociception, Hyperthermia, and Suppression of Activity Produced by Morphine (2021) (3)
- Behavioral Battery for Testing Candidate Analgesics in Mice. II. Effects of Endocannabinoid Catabolic Enzyme Inhibitors and ∆9-Tetrahydrocannabinol (2021) (3)
- Changes in tail skin temperature are unlikely to be a confounding factor in the tail-flick test (1994) (3)
- Behavioral effects of cannabinoid agonists (2000) (2)
- Diacylglycerol Lipase-β Knockout Mice Display a Sex-Dependent Attenuation of Traumatic Brain Injury-Induced Mortality with No Impact on Memory or Other Functional Consequences. (2021) (2)
- Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters (2014) (2)
- Just add water: cannabinoid discrimination in a water T-maze with FAAH(−/−) and FAAH(+/+) mice (2016) (2)
- The Genetics of Cannabis Use and Cannabis Use Disorders (2013) (2)
- D 9-Tetrahydrocannabinol and Endocannabinoid Degradative Enzyme Inhibitors Attenuate Intracranial Self-Stimulation in Mice s (2014) (2)
- The Endocannabinoid System as a Target for Treatment of Breast Cancer (2009) (2)
- Cannabichromene and tetrahydrocannabinol determination in mouse blood and brain by gas chromatography-mass spectrometry. (2011) (2)
- Inactivation of fatty acid amide hydrolase protects against ischemic reperfusion injury-induced renal fibrogenesis. (2022) (2)
- Effects of chemotherapy on operant responding for palatable food in male and female mice (2021) (2)
- Integration of Molecular and Behavioral Approaches to Evaluate Cannabinoid Dependence (2003) (2)
- The Endogenous Cannabinoid System: A Cadre of Potential Therapeutic Targets (2018) (1)
- CANNABINOIDS ARE NEUROPROTECTIVE AGAINST HIV‐1 TAT AND OCCLUDE THE TAT‐INDUCED DECREASE IN GABAERGIC NEUROTRANSMISSION IN PREFRONTAL CORTEX SLICES (2016) (1)
- Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms (2022) (1)
- alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain (2011) (1)
- Global cannabinoid receptor 1 deficiency affects disuse-induced bone loss in a site-specific and sex-dependent manner. (2022) (1)
- Abstract 1453: The cannabinoid Win55, 212-2 enhances the response of breast cancer cells to radiation (2012) (1)
- Short communication Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB 1 receptors (2007) (1)
- Elevation of Endocannabinoids via Inhibition of their Catabolic Enzymes Attenuates the Precipitated Opioid Withdrawal Syndrome (2010) (1)
- CB1 receptor transgenic mice in the cannabinoid triad: a novel approach to assess in vivo efficacy of CB1 ligands. (2015) (0)
- Differing Roles of S1P Receptor Adaptation in FTY720‐Induced Antinociception in Acute Versus Neuropathic Pain (2017) (0)
- Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system (2013) (0)
- Dual blockade of endocannabinoid hydrolyzing enzymes reveal a CB1 receptor-mediated interoceptive stimulus (2015) (0)
- Knockout of fatty acid amide hydrolase (FAAH) gene attenuates cisplatin‐induced nephrotoxicity in mice (2022) (0)
- Inhibition of both FAAH and MAGL, but not either separately, produces delta‐9‐THC like discriminative stimulus effects (2013) (0)
- Abstract P468: Stimulation of Diuresis and Salt Excretion by Renomedullary Infusion of a Dual Inhibitor of Fatty Acid Amide Hydrolase (FAAH) and Monoacylglycerol Lipase (MAGL) (2017) (0)
- Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine (2019) (0)
- Analgesic Properties of THC and Its Synthetic Derivatives (1999) (0)
- Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids (2020) (0)
- Fatty acid amide hydrolase (FAAH) inhibition mitigates TGF‐β1‐induced fibrogenesis via the anandamide‐COX‐2‐dependent pathway (2022) (0)
- Aerosoldosiergeräte compositions for delta 9 tetrahydrocannabinol (delta 9 THC) and methods of use (1999) (0)
- Metered dose inhalers of dissolution of delta 9-tetrahydrocannabinol (delta 9-THC) and methods of use. (1999) (0)
- Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge (2015) (0)
- Microsoft Word-1197974-file00.docx (2015) (0)
- RGS9‐2 differentially regulates adenylyl cyclase signaling by opioid and cannabinoid receptors in the mouse CNS (2008) (0)
- Results of a double-blind, randomized, placebo-controlled study of Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic uncontrolled pain (2017) (0)
- Running Title : Diacylglycerol lipase in inflammatory pain * (2017) (0)
- Oxycodone Produces Antinociception, but Worsens Functional Behaviors, in Humanized Sickle Cell Disease Mice (2022) (0)
- Monoacylglycerol Lipase Inhibition: A Strategy to Treat Chronic Pain in a Humanized Sickle Cell Mouse Model (2021) (0)
- Investigation of Cannabidiol in the Mouse Drug Discrimination Paradigm. (2023) (0)
- Medical Science 7 nAChR NEGATIVE ALLOSTERISM : A PROMISING APPROACH FOR COGNITIVE DISORDERS (0)
- 106. Neuropathic pain is attenuated by a cannabinoid mechanism of action (2008) (0)
- Assessment of Monoacyglycerol Lipase Inhibition for Acute and Chronic Antinociception in a Behavioral Battery for Testing Candidate Analgesics in Mice (2021) (0)
- The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice (2013) (0)
- Endocannabinoid catabolic enzyme inhibitors reduce opioid withdrawal responses (2011) (0)
- Pediatric blood and cancer (2011) (0)
- Marble Burying: A Novel Measure of Murine Neuropathic Pain Depressed Behavior (2015) (0)
- Anandamide and its metabolites as novel natriuretic and antihypertensive lipids from the renal medulla (2012) (0)
- Summary Cannabis in India: Ancient lore and modern medicine (2019) (0)
- Inhibition of cannabinoid metabolic enzymes reduces NSAID‐induced gastric pathology (2011) (0)
- Topical Win55 212–2 Reduces Intraocular Pressure in Ocular Hypertensive Rats (2004) (0)
- The ontogenesis of lithium-induced effects on suckling: inhibition and facilitation. (1989) (0)
- Targeted Deletion of Sphingosine‐1‐Phosphate Receptor Type 1 (S1PR1) Reveals a Predominant Functional Localization of S1PR1 in Astrocytes in the Spinal Cord (2021) (0)
- Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices (2016) (0)
- Involvement of the Endocannabinoid System in the Development and Treatment of Breast Cancer (2014) (0)
- Cannabinoid1 receptors in the hippocampus mediate the deleterious effects of cannabinoid agonists on spatial memory assessed in the radial arm maze (2008) (0)
- Structural basis of selective cannabinoid CB2 receptor activation (2023) (0)
- Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague–Dawley rats (2019) (0)
- The Anandamide Cyclooxygenase‐2 Metabolite, Prostamide E2, as a Novel Diuretic and Natriuretic Lipid in the Mouse Renal Medulla (2013) (0)
- Inhibiting endocannabinoid catabolic enzymes attenuates neuropathic pain via distinct cannabinoid receptor mediated mechanisms of action (2010) (0)
- Chemokine-mediated angiogenesis : an essential link in the evolution of airway fibrosis ? (2005) (0)
- The FAAH inhibitor URB‐597 ameliorates cannabinoid withdrawal in mice (2008) (0)
- Microsoft Word-25600871-file00.docx (2013) (0)
- Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function (2015) (0)
- Cannabichromene andTetrahydrocannabinol Determination in Mouse Blood and Brain by Gas Chromatography – Mass Spectrometry (0)
- Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice (2023) (0)
- Mice lacking fatty acid amide hydrolase have facilitated acquisition of anandamide discriminative stimulus, (2008) (0)
- Effects of GAT107, an Allosteric Agonist and Positive Modulator of α7 Nicotinic Acetylcholine Receptors, on Chronic Inflammatory and Neuropathic Pain in Mice (2015) (0)
- 35. Differential effects of endocannabinoid catabolic enzyme inhibition on thermal homeostasis following environmental or immunological stressors (2014) (0)
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