Arthur Lander | Academic Influence

Arthur Lander's AcademicInfluence.com Rankings

Arthur Lander

Biology

#1490

World Rank

#2487

Historical Rank

Developmental Biology

#108

World Rank

#114

Historical Rank

Molecular Biology

#905

World Rank

#928

Historical Rank

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Biology

Arthur Lander's Degrees

PhD Biology University of California, Berkeley
Bachelors Biology Stanford University

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Why Is Arthur Lander Influential?

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According to Wikipedia, Arthur D. Lander an American biologist who is Director of the Center for Complex Biological Systems at the University of California, Irvine. Education He was born in Brooklyn, New York, and is an alumnus of John Dewey High School there. He received a Bachelor of Arts from Yale University and a combined M.D., Ph.D. from the University of California, San Francisco, under the direction of Louis Reichardt. His first faculty position was jointly in the Department of Brain and Cognitive Sciences and the Department of Biology at Massachusetts Institute of Technology. He moved as Professor to Irvine in 1995.

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Arthur Lander's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons (1992) (900)
Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B (2004) (683)
Do morphogen gradients arise by diffusion? (2002) (426)
Differential binding of chemokines to glycosaminoglycan subpopulations (1994) (374)
The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer. (1998) (349)
Laminin is associated with the "neurite outgrowth-promoting factors" found in conditioned media. (1985) (348)
Morpheus Unbound: Reimagining the Morphogen Gradient (2007) (335)
Cell surface glypicans are low-affinity endostatin receptors. (2001) (305)
Cell Lineages and the Logic of Proliferative Control (2009) (294)
Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells. (2001) (264)
Enhanced glypican-3 expression differentiates the majority of hepatocellular carcinomas from benign hepatic disorders (2001) (262)
Characterization of a factor that promotes neurite outgrowth: evidence linking activity to a heparan sulfate proteoglycan (1982) (258)
A diverse set of developmentally regulated proteoglycans is expressed in the rat central nervous system (1990) (254)
Complex Regulation of cyp26a1 Creates a Robust Retinoic Acid Gradient in the Zebrafish Embryo (2007) (237)
Multiple Organ System Defects and Transcriptional Dysregulation in the Nipbl +/− Mouse, a Model of Cornelia de Lange Syndrome (2009) (235)
GDF11 Controls the Timing of Progenitor Cell Competence in Developing Retina (2005) (217)
Purification of a factor that promotes neurite outgrowth: isolation of laminin and associated molecules (1985) (210)
Pattern, Growth, and Control (2011) (195)
The Elusive Functions of Proteoglycans (2000) (184)
What does the concept of the stem cell niche really mean today? (2012) (182)
Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation (1994) (177)
Formation of the BMP activity gradient in the Drosophila embryo. (2005) (177)
Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations (2015) (175)
Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior. (1994) (171)
Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells. (2008) (155)
Regulation of Neurite Outgrowth by Integrin Activation (2000) (150)
Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: development of a sensitive electrophoretic approach. (1991) (146)
Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain. (1997) (142)
Free Extracellular Diffusion Creates the Dpp Morphogen Gradient of the Drosophila Wing Disc (2012) (136)
Inhibitors and Promoters of Thalamic Neuron Adhesion and Outgrowth in Embryonic Neocortex: Functional Association with Chondroitin Sulfate (1996) (135)
Expression of the heparan sulfate proteoglycan glypican‐1 in the developing rodent (1998) (131)
Heparin-binding properties of the amyloidogenic peptides Abeta and amylin. Dependence on aggregation state and inhibition by Congo red. (1997) (130)
Heparan Sulfate Proteoglycans as Adhesive and Anti-invasive Molecules (1998) (128)
Identifying gene regulatory networks in schizophrenia (2010) (120)
Widespread Defects in the Primary Olfactory Pathway Caused by Loss of Mash1 Function (2003) (120)
Proteoglycans in the nervous system (1993) (119)
Growth factor–induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells (2005) (119)
Proteoglycans: master regulators of molecular encounter? (1998) (118)
Understanding the molecules of neural cell contacts: emerging patterns of structure and function (1989) (116)
Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate (2011) (110)
Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis (2009) (109)
Feedback regulation in multistage cell lineages. (2008) (109)
Cohesin Mediates Chromatin Interactions That Regulate Mammalian β-globin Expression* (2011) (103)
Heparan Sulfate Acts as a Bone Morphogenetic Protein Coreceptor by Facilitating Ligand-induced Receptor Hetero-oligomerization (2010) (100)
Interdomain Interactions of Radixin in Vitro(*) (1995) (99)
How Cells Know Where They Are (2013) (98)
Mapping the heparin-binding sites on type I collagen monomers and fibrils (1994) (97)
Secreted Glypican Binds to the Amyloid Precursor Protein of Alzheimer's Disease (APP) and Inhibits APP-induced Neurite Outgrowth* (1996) (97)
Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: assessment of selectivity, heterogeneity and the participation of core proteins in binding. (1999) (97)
The edges of understanding (2010) (88)
Mechanisms Underlying Preferential Assembly of Heparan Sulfate on Glypican-1* (2001) (88)
Multifactorial Origins of Heart and Gut Defects in nipbl-Deficient Zebrafish, a Model of Cornelia de Lange Syndrome (2011) (88)
Dynamics and precision in retinoic acid morphogen gradients. (2012) (88)
Adhesion of B lymphoid (MPC-11) cells to type I collagen is mediated by integral membrane proteoglycan, syndecan. (1992) (86)
Studies on extracellular matrix components that promote neurite outgrowth. (1983) (85)
Specificity in the interactions of extracellular matrix proteins with subpopulations of the glycosaminoglycan heparin. (1993) (83)
The 'stem cell' concept: is it holding us back? (2009) (81)
The measure of success: constraints, objectives, and tradeoffs in morphogen-mediated patterning. (2009) (77)
Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11 (2009) (77)
Immunopurification and characterization of a neuronal heparan sulfate proteoglycan (1985) (75)
Mini-Review The Elusive Functions of Proteoglycans: In Vivo Veritas (2000) (72)
The glypican family of heparan sulfate proteoglycans: major cell-surface proteoglycans of the developing nervous system. (1996) (72)
Multispecies model of cell lineages and feedback control in solid tumors. (2012) (71)
Cerebroglycan, a developmentally regulated cell-surface heparan sulfate proteoglycan, is expressed on developing axons and growth cones. (1997) (70)
Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells. (1999) (66)
Cellular retinoic acid-binding proteins are essential for hindbrain patterning and signal robustness in zebrafish (2012) (62)
Heparan Sulfate Proteoglycans as Adhesive and Anti-invasive Molecules SYNDECANS AND GLYPICAN HAVE DISTINCT FUNCTIONS* (1998) (61)
A Calculus of Purpose (2004) (61)
Characterization of cytokeratin 20 expression in pancreatic and colorectal cancer. (1999) (60)
Interactions of syndecan-1 and heparin with human collagens. (1994) (60)
Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development (2014) (57)
Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue (2009) (55)
Heparin inhibits the attachment and growth of Balb/c‐3T3 fibroblasts on collagen substrata (1992) (51)
Analysis of DNA-protein interactions by affinity coelectrophoresis. (1991) (49)
Association of ezrin isoforms with the neuronal cytoskeleton (1991) (45)
Spatiotemporal mechanisms of morphogen gradient interpretation. (2011) (45)
A reaction–diffusion mechanism influences cell lineage progression as a basis for formation, regeneration, and stability of intestinal crypts (2012) (45)
Spatial dynamics of multistage cell lineages in tissue stratification. (2010) (44)
Laminar specific attachment and neurite outgrowth of thalamic neurons on cultured slices of developing cerebral neocortex. (1994) (43)
Membrane-Associated Non-Receptors and Morphogen Gradients (2007) (40)
Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome. (2013) (40)
Spatially distributed morphogen production and morphogen gradient formation. (2005) (39)
Targeting the glycosaminoglycan-binding sites on proteins. (1994) (39)
Pertussis toxin specifically inhibits growth cone guidance by a mechanism independent of direct G protein inactivation (1995) (38)
Feedback, Lineages and Self-Organizing Morphogenesis (2016) (38)
Computational analysis of BMP gradients in dorsal-ventral patterning of the zebrafish embryo. (2007) (37)
Patterns of Chondroitin Sulfate Immunoreactivity in the Developing Tectum Reflect Regional Differences in Glycosaminoglycan Biosynthesis (1998) (33)
Cell lineage branching as a strategy for proliferative control (2015) (33)
The genetics of alcohol dependence: advancing towards systems-based approaches. (2012) (32)
The Protective Role of Symmetric Stem Cell Division on the Accumulation of Heritable Damage (2014) (30)
Internalization and end flux in morphogen gradient formation (2006) (29)
Neuronal Receptors Mediating Responses to AntibodyActivated Laminin-1 (1998) (29)
A BMP-FGF Morphogen Toggle Switch Drives the Ultrasensitive Expression of Multiple Genes in the Developing Forebrain (2014) (29)
Foxg 1 promotes olfactory neurogenesis by antagonizing Gdf 11 (2009) (27)
The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome (2017) (27)
Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. (2017) (26)
Using mouse and zebrafish models to understand the etiology of developmental defects in Cornelia de Lange Syndrome (2016) (25)
Size-normalized Robustness of Dpp Gradient in Drosophila Wing Imaginal Disc. (2011) (24)
Mechanisms by which molecules guide axons. (1990) (24)
Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects (2016) (23)
Feedback Regulation of Neurogenesis in the Mammalian Olfactory Epithelium: New Insights from Genetics and Systems Biology (2010) (22)
Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster (2012) (22)
Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I (2013) (22)
Aggregation of a Distributed Source in Morphogen Gradient Formation (2005) (20)
Scaling a Dpp Morphogen Gradient through Feedback Control of Receptors and Co-receptors. (2020) (20)
ROBUSTNESS OF SIGNALING GRADIENT IN DROSOPHILA WING IMAGINAL DISC. (2011) (20)
Heparin-binding Properties of the Amyloidogenic Peptides Aβ and Amylin (1997) (20)
Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms (2015) (19)
NTR 2.0: a rationally-engineered prodrug converting enzyme with substantially enhanced efficacy for targeted cell ablation (2020) (18)
Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes (2020) (16)
Can morphogen activity be enhanced by its inhibitors (2003) (16)
Localized Ectopic Expression of Dpp Receptors in a Drosophila Embryo (2009) (14)
Multiple Paths to Morphogen Gradient Robustness (2005) (14)
Molecules that make axons grow (2008) (13)
Extracellular matrix in the developing nervous system (1993) (12)
Cohesin Mediates Chromatin Interactions That Regulate Mammalian (cid:1) -globin Expression * (2011) (12)
Cell surface proteoglycans in signalling and development (1999) (12)
The individuality of stem cells (2011) (10)
Genetic enhancement of limb defects in a mouse model of Cornelia de Lange syndrome (2016) (9)
Basal forebrain cholinergic cell attachment and neurite outgrowth on organotypic slice cultures of hippocampal formation (2002) (8)
Expanding signaling-molecule wavefront model of cell polarization in the Drosophila wing primordium (2017) (8)
Discovery of a Novel Molecule that Regulates Tumor Growth and Metastasis (2008) (7)
Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: Abstracts from the 2014 Scientific and Educational Symposium (2015) (7)
Title Heparin-binding properties of the amyloidogenic peptides Aβ and amylin : Dependence on aggregation state and inhibition by Congo red Permalink (1997) (7)
Generation, Differentiation, and Maturation of Olfactory Receptor Neurons In Vitro (1994) (7)
Affinity coelectrophoresis of proteoglycan-protein complexes. (2001) (5)
Analysis of Protein-Glycosaminoglycan Interactions by Affinity Co-Electrophoresis (1997) (4)
Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis (2016) (4)
Regulatory Feedbacks on Receptor and Non-receptor Synthesis for Robust Signaling (2019) (4)
Optimal experimental design for mathematical models of haematopoiesis (2021) (4)
Making sense in biology: an appreciation of Julian Lewis (2014) (4)
Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I (2013) (4)
Diverse Paths to Morphogen Gradient Robustness (2005) (3)
The cohesin loader NIPBL interacts with pre-ribosomal RNA and treacle to regulate ribosomal RNA synthesis (2019) (3)
Insights Into Cornelia de Lange Syndrome From the Nipbl-Mutant Mouse (2009) (3)
Predicting mechanism of biphasic growth factor action on tumor growth using a multi-species model with feedback control. (2013) (3)
Title Multifactorial Origins of Heart and Gut Defects in nipbl-Deficient Zebrafish , a Model of Cornelia de Lange Syndrome Permalink (2011) (3)
Using organotypic tissue slices as substrata for the culture of dissociated cells. (2000) (2)
Semantic analysis and synthesis of complex biological systems (2004) (2)
Elaboration of a Multispecies Model of Solid Tumor Growth with Tumor-Host Interactions (2014) (2)
Dynamic readout of the Hh gradient in the Drosophila wing disc reveals pattern-specific tradeoffs between robustness and precision (2022) (2)
Left-right symmetry and asymmetry. (1996) (2)
Distributed Individual-Based Simulation (2009) (2)
Decreasing Wapl dosage partially corrects transcriptome phenotypes in Nipbl-/+ embryonic mouse brain (2022) (2)
Regulation of endoderm development by zebrafish Nipbl (2010) (1)
Title Elaboration of a multispecies model of solid tumor growth with tumor-host interactions Permalink (2014) (1)
1 Supporting Information Spatial Dynamics of Multi-stage Cell Lineages in Tissue Stratification (2010) (1)
Opinions on left-right axis formation. (1995) (1)
MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses (2021) (1)
Feedback control of morphogen gradient scale (2019) (1)
Scaling a Dpp morphogen gradient through feedback control of receptors and co-receptors. Zhu et al. (2020) (1)
Making sense in biology: an appreciation of Julian Lewis (2014) (1)
Decreasing Wapl dosage partially corrects embryonic growth and brain transcriptome phenotypes in Nipbl+/− embryos (2022) (1)
When oncogenes do not cause cancer (2021) (1)
Title Secreted glypican binds to the amyloid precursor protein of Alzheimer ' s disease ( APP ) and inhibits APP-induced neurite outgrowth Permalink (1996) (0)
GR-02 A cross-inhibitory positive feedback mechanism establishes a robust sharp border in the forebrain (2009) (0)
Opinions on left-right axis formation. Author's reply (1995) (0)
The engineering of developmental regulation (2008) (0)
Morphogen Cellular retinoic acid-binding proteins are essential for hindbrain patterning and signal robustness in (2012) (0)
Laminin is associated with the "nei factors" found in conditioned medio (extracellular matrix/cell-substratum interaction/axonal growth and (2016) (0)
Contributors (2002) (0)
Title Spatiotemporal mechanisms of morphogen gradient interpretation (2011) (0)
Glypican-1 is crucial for the angiogenic and metastatic potential of pancreatic cancer cells (2008) (0)
Works Title Modeling Early Developmental Defects in Cornelia de Lange Syndrome Using the Zebrafish Permalink (2015) (0)
Leveraging gene correlations in single cell transcriptomic data (2023) (0)
The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome (2017) (0)
Title Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects (2016) (0)
690 Characterization of the amyloidogenic subunits Aß1–40. Aβ1–42, Aβ1–40 (Dutch) and amylin: heparin-binding properties and multiple effects of Congo red (1996) (0)
What does the concept of the stem cell niche really mean today? (2012) (0)
Spatial organization of the 3D genome encodes gene co-expression programs in single cells (2022) (0)
Modeling Early Developmental Defects in Cornelia de Lange Syndrome Using the Zebrafish (2009) (0)
079 Identifying signaling networks in melanoma tumors that promote the uncontrolled growth of BRAF mutant melanocytes (2022) (0)
Developmental defects in multiple organ systems in a mouse model of Cornelia de Lange Syndrome (2006) (0)
Cell lineage branching as a strategy for proliferative control (2015) (0)
Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy (2022) (0)
hindbrain patterning and signal robustness in zebrafish (2012) (0)
Investigating the Origins of Congenital Heart Defects in a Mouse Model of Cornelia de Lange Syndrome (2019) (0)
Title Multiple organ system defects and transcriptional dysregulation in the Nipbl + /-mouse , a model of Cornelia de Lange syndrome (2009) (0)
Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. (2023) (0)
C O M M E N T Open Access (2011) (0)
Procede d'inactivation virale (1993) (0)
C O MMENT Open Access (2011) (0)
Roles of zebrafish Nipped-B-like (Nipbl) in gene regulation (2009) (0)
Cornelia de Lange Syndrome (2020) (0)
Do Morphogen Gradients Arise by Diffusion ? with diffusive tranpsort (2002) (0)
Table of Contents, Volume 172C, Number 2, June 2016 (2016) (0)
MULTISTAGE CELL LINEAGES (2008) (0)
Making sense in biology: an appreciation of (2014) (0)
1 Multi-stage Stem Cell Lineages and Tissue Stratification (0)
Purification Isolation of of a Factor That Promotes Neurite Laminin and Associated Molecules Outgrowth: (2002) (0)
Interactions of syndecan-1 and heparin with collagens (1994) (0)
The Role of NIPBL in Cornelia de Lange Syndrome (2015) (0)
Regulatory feedback effects on tissue growth dynamics in a two-stage cell lineage model. (2021) (0)
Genetic interactions of cell intrinsic factors and secreted signals regulateneurogenesis in olfactory epithelium / 細胞内因子と分泌シグナル因子の反作用による嗅覚上皮神経発生の制御 - eScholarship (2012) (0)
Understanding the Combinatorial Fragility of Life (2017) (0)
Abnormalities of Limb Development in Vertebrate Animal Models of CdLS (2015) (0)
A follistatin-BMP7 feedback circuit controls taste papillae development and patterning in mouse tongue (2009) (0)
Nipbl regulates organ laterality and Kupffer's vesicle development in Zebrafish (2011) (0)

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