Arturo Falaschi
Italian geneticist
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Biology
Arturo Falaschi's Degrees
- PhD Genetics University of Pavia
- Bachelors Biology University of Pavia
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(Suggest an Edit or Addition)According to Wikipedia, Arturo Falaschi was an Italian geneticist. Biography He graduated in Medicine in 1957 from University of Milan and undertook two post doctoral studies. Firstly, with J. Adler and Har Gobind Khorana in Wisconsin, USA , and later with Arthur Kornberg at Stanford . His main field of research was the replication of DNA. He was Professor of Molecular Biology at the University of Pavia ; Director of the Instituto di Genetica Biochimica ed Evoluzionistica, CNR, Pavia ; and Director of the Progetto Finalizzato "Ingegneria Genetica" of the Italian National Research Council . He taught Molecular Biology at the University of Pavia and remained Director of Graduate School of Genetics, University of Pavia . He was coordinator of the Graduate School of Molecular Genetics, International School of Advanced Studies , Trieste and Professor of Molecular Biology, Scuola Normale Superiore , Pisa, Italy from 2004 to his last breath. He researched mainly in the field of DNA replication and in the last decades of his life he searched in particular the origin of replication of human DNA, discovering the first documented origin .
Arturo Falaschi's Published Works
Published Works
- A novel procedure for quantitative polymerase chain reaction by coamplification of competitive templates. (1992) (275)
- Clinical StudiesFamilial dilated cardiomyopathy: Evidence for genetic and phenotypic heterogeneity☆ (1999) (217)
- Start sites of bidirectional DNA synthesis at the human lamin B2 origin. (2000) (196)
- A new locus for arrhythmogenic right ventricular dysplasia on the long arm of chromosome 14. (1996) (186)
- Familial dilated cardiomyopathy: evidence for genetic and phenotypic heterogeneity. Heart Muscle Disease Study Group. (1999) (169)
- Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1 (1996) (164)
- A point mutation in the 5' splice site of the dystrophin gene first intron responsible for X-linked dilated cardiomyopathy. (1996) (158)
- Linkage of familial dilated cardiomyopathy to chromosome 9. Heart Muscle Disease Study Group. (1995) (147)
- Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation (2010) (139)
- A new phage of Bacillus subtilis with infectious DNA having separable strands. (1968) (116)
- Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression (2003) (107)
- Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A. (2004) (107)
- Modular Structure of the Human Lamin B2 Replicator (2004) (106)
- Dystrophin gene abnormalities in two patients with idiopathic dilated cardiomyopathy (1997) (84)
- Characterization of the DNA-unwinding Activity of Human RECQ1, a Helicase Specifically Stimulated by Human Replication Protein A* (2003) (83)
- Localization of proteins bound to a replication origin of human DNA along the cell cycle (2003) (82)
- High-resolution mapping of the origin of DNA replication in the hamster dihydrofolate reductase gene domain by competitive PCR (1996) (81)
- Nested polymerase chain reaction for high-sensitivity detection of enteroviral RNA in biological samples (1993) (81)
- Familial dilated cardiomyopathy. (1994) (80)
- Variations of DNA polymerase-alpha and -beta during prolonged stimulation of human lymphocytes. (1976) (74)
- Mapping replication origins by quantifying relative abundance of nascent DNA strands using competitive polymerase chain reaction. (1997) (74)
- Low frequency of detection by nested polymerase chain reaction of enterovirus ribonucleic acid in endomyocardial tissue of patients with idiopathic dilated cardiomyopathy. (1994) (73)
- A human binding site for transcription factor USF/MLTF mimics the negative regulatory element of human immunodeficiency virus type 1. (1992) (72)
- Cell cycle modulation of protein–DNA interactions at a human replication origin (1998) (68)
- In vivo footprinting analysis of constitutive and inducible protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1 (1993) (64)
- Human DNA helicase VIII: a DNA and RNA helicase corresponding to the G3BP protein, an element of the ras transduction pathway. (1999) (64)
- STUDIES ON THE MECHANISM OF ACTION OF PEDERINE (1968) (60)
- Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents. (1997) (60)
- Studies on the mode of action of nalidixic acid. (1972) (57)
- Replication origins of mammalian chromosomes: the happy few. (1999) (56)
- CHEMICALLY SYNTHESIZED DEOXYPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE. (1963) (54)
- Utilization of the same DNA replication origin by human cells of different derivation. (1996) (54)
- Functional Properties of the Separate Subunits of Human DNA Helicase II/Ku Autoantigen* (1997) (53)
- Molecular and functional interactions of transcription factor USF with the long terminal repeat of human immunodeficiency virus type 1 (1995) (52)
- Functional interactions of DNA topoisomerases with a human replication origin (2007) (52)
- In vivo protein-DNA interactions at human DNA replication origin. (1996) (51)
- Studies on the Mode of Ku Interaction with DNA* (2002) (47)
- Selection of homeotic proteins for binding to a human DNA replication origin. (2000) (46)
- Interactions of USF and Ku antigen with a human DNA region containing a replication origin. (1993) (43)
- A DNA helicase from human cells. (1990) (43)
- DNA helicase IV from HeLa cells (1991) (41)
- Characterization of human DNA sequences synthesized at the onset of S-phase. (1987) (40)
- Control of cell division by aphidicolin without adverse effects upon resting cells. (1985) (39)
- ANTIMETABOLITES AFFECTING PROTEIN OR NUCLEIC ACID SYNTHESIS. PHLEOMYCIN, AN INHIBITOR OF DNA POLYMERASE. (1964) (39)
- Purification and properties of a polynucleotide ligase from human cell cultures. (1971) (38)
- A rapid procedure for the quantitation of low abundance RNAs by competitive reverse transcription-polymerase chain reaction. (1994) (38)
- Human DNA helicase V, a novel DNA unwinding enzyme from HeLa cells. (1993) (36)
- Eukaryotic DNA replication: a model for a fixed double replisome. (2000) (36)
- Fate of exogenous recombinant plasmids introduced into mouse and human cells. (1985) (35)
- Two forms of the DNA ligase of human cells. (1973) (35)
- DNA helicase III from HeLa cells: an enzyme that acts preferentially on partially unwound DNA duplexes. (1992) (33)
- Molecular and Structural Transactions at Human DNA Replication Origins (2007) (32)
- Is DNA sequence sufficient to specify DNA replication origins in metazoan cells? (2004) (32)
- DNA replication in mammalian cells. I. The size of newly synthesized helices. (1970) (32)
- Biochemical studies of bacterial sporulation. II. Deoxy- ribonucleic acid polymerase in spores of Bacillus subtilis. (1966) (30)
- The homeotic protein HOXC13 is a member of human DNA replication complexes (2009) (30)
- Rapid retrovirus titration using competitive polymerase chain reaction. (1996) (29)
- Identification of human DNA helicase V with the far upstream element-binding protein. (2001) (28)
- Probing protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1 by in vivo footprinting (1992) (27)
- Homeotic proteins participate in the function of human-DNA replication origins (2010) (27)
- The Three DNA Polymerases of Animal Cells: Properties and Functions (1978) (24)
- In Vitro Protein-DNA Interactions at the Human Lamin B2 Replication Origin* (2003) (23)
- Molecular genetics of dilated cardiomyopathy. (1994) (22)
- Presence of transcription signals in two putative DNA replication origins of human cells. (1988) (22)
- Evidence for two waves of induction of DNA enzymes in stimulated human lymphocytes. (1974) (21)
- A somatostatin analogue induces translocation of Ku 86 autoantigen from the cytosol to the nucleus in colon tumour cells. (1998) (20)
- A lipopolysaccharide inhibitor of a DNA methyl transferase. (1965) (19)
- Enhancement of the rate of DNA polymerase-alpha activity on duplex DNA by a DNA-binding protein and a DNA-dependent ATPase of mammalian cells. (1979) (19)
- Incorporation of (3H)thymidine stimulated by ultraviolet radiation into human fibroblast cultures. (1976) (19)
- Effect of deoxyribonucleic acid replication inhibitors on bacterial recombination (1976) (18)
- Induction of polynucleotide ligase in human lymphocytes stimulated by phytohemoagglutinin. (1972) (18)
- DNA replication, development and cancer: a homeotic connection? (2010) (18)
- Dependence of the buoyant density of single-stranded DNA on base composition. (1969) (18)
- A human DNA replication origin: localization and transcriptional characterization (2006) (18)
- Purification of BrdUrd-substituted DNA by immunoaffinity chromatography with anti-BrdUrd antibodies. (1992) (17)
- DNA-binding proteins and DNA-unwinding enzymes in eukaryotes (1980) (16)
- A protein target site in an early replicated human DNA sequence: a highly conserved binding motif. (1989) (15)
- Molecular genetics of dilated cardiomyopathies. (1995) (15)
- Control of DNA Replication and Cell Proliferation in Eukaryotes by Aphidicolin (1984) (15)
- Variations of DNA polymerases-a and -3 during prolonged stimulation of human lymphocytes (15)
- Genetic and enzymic studies on the recombination process in Bacillus subtilis (2004) (13)
- A novel endonuclease of human cells specific for single-stranded DNA. (1976) (13)
- Searching for replication origins in mammalian DNA. (1993) (12)
- Similia similibus: Pairing of homologous chromosomes driven by the physicochemical properties of DNA (2008) (12)
- Genetic factors in dilated cardiomyopathy. (1996) (11)
- Levels of some enzymes acting on DNA in xeroderma pigmentosum. (1974) (11)
- Levels of DNA polymerase-alpha and beta in normal and xeroderma pigmentosum fibroblasts (1977) (10)
- Enhancement of gene targeting in human cells by intranuclear permeation of the Saccharomyces cerevisiae Rad52 protein (2010) (10)
- International Centre for Genetic Engineering and Biotechnology (2018) (9)
- Inhibition of heterologous DNA replication by the MVMp nonstructural NS-1 protein: identification of a target sequence. (1993) (9)
- Properties of a Bacillus subtilis strain lacking DNA polymerase I. (1974) (8)
- Modulation of deoxyribonucleic acid polymerase III level during the life cycle of Bacillus subtilis (1977) (8)
- Isolation of the hybrid between ribosomal RNA and DNA of Bacillus subtilis. (1968) (8)
- An intracellular endonuclease of Bacillus subtilis specific for single-stranded DNA. (1976) (8)
- Total purification of a DNA‐dependent ATPase and of a DNA‐binding protein from human cells. (1983) (7)
- Absence of linkage between idiopathic dilated cardiomyopathy and candidate genes involved in the immune function in a large Italian pedigree. (1994) (7)
- A new mutant of Bacillus subtilis altered in the initiation of chromosome replication (2004) (6)
- Functional reconstitution of oxidase activity in X-linked chronic granulomatous disease by retrovirus-mediated gene transfer. (1996) (6)
- A modified protocol for in vivo footprinting by ligation-mediated polymerase chain reaction. (1994) (6)
- On the identity of dnaP and dnaF genes of Bacillus subtilis (1976) (6)
- Binding of DNA topoisomerases I and II to replication origins. (2009) (5)
- 2 Eukaryotic DNA Replication Origins (2006) (5)
- Enzymic purification of a hybrid between ribosomal ribonucleic acid and deoxyribonucleic acid. (1971) (5)
- Variations of DNA repair synthesis after UV irradiation in PHA stimulated lymphocytes. (1979) (5)
- Isolation of a high-molecular-weight hybrid between ribosomal RNA and DNA. (1972) (5)
- Bacillus subtilis deoxyribonuclease activity specific for single-stranded deoxyribonucleic acid: cellular site and variations during germination and sporulation (1980) (4)
- Frontiers in life science. (2010) (4)
- Effect of radiations on heart lactic dehydrogenase and pancreas ribonuclease and protective action of a sulfanilamide disulfide. (1962) (4)
- DNA Repair in Human Cells: Enzymes and Mutants (1978) (3)
- Stimulation of the DNA unwinding activity of human DNA helicase II/Ku by phosphorylation. (2008) (3)
- Properties of the high-molecular-weight deoxyribonuclease of Bacillus subtilis degrading single-stranded DNA. (1978) (3)
- Gene therapy of chronic granulomatous disease (CGD) by gene transfer into hematopoietic stem cells. (1998) (3)
- The quest for a human ori. (1994) (3)
- Nalidixic acid does not inhibit bacterial transformation (2004) (3)
- Familial dilated cardiomyopathy with subclinical skeletal muscle involvement (1996) (2)
- A simplified procedure for the analysis of DNA polymerase III levels in Bacillus subtilis strains. (1976) (2)
- Changing disciplinary borders into frontiers of progress (2007) (2)
- Sequence-specific DNA binding protein(s) that bind(s) to a putative human DNA replication origin. (1988) (2)
- A DNA dependent ATPase from HeLa cells. (1982) (2)
- Editorial: Frontiers in Life Science (2010) (1)
- In vivo protein-DNA interactions at a human DNA replication origin ( lamin B 2 / origin-binding proteins / ligation-mediated PCR / genomic footprinting ) (2005) (1)
- Funding assured for India's international biotechnology centre . . . (2001) (1)
- Benefits from Cooperation in Biotechnology: The Experience of The International Centre for Genetic Engineering and Biotechnology (2002) (1)
- A point mutation in the 5′ splice site of the first intron of the dystrophin gene responsible for X-linked dilated cardiomyopathy (1996) (1)
- Molecular mechanics and DNA replication regulation (2007) (1)
- The quest for a humanori (2005) (1)
- The HFSP Journal one year on: moving forward with a new feature. (2008) (0)
- Searching for proteins and sequences of DNA replication in mammalian cells. (1984) (0)
- NestedPolymerase ChainReaction forHigh-Sensitivity Detection ofEnteroviral RNA inBiological Samples (1993) (0)
- Preface (1993) (0)
- DNA polymerase accessory proteins in mammalian cells. (1984) (0)
- TheGenefora NovelHumanLaminMapsata Highly Transcribed LocusofChromosome 19which Replicates attheOnsetofS-Phase (1992) (0)
- Linkage of autosomal dominant familial dilated cardiomyopathy to chromosome 9 (1996) (0)
- Dilated Cardiomyopathy: Does Etiological Heterogeneity Portend Clinical Heterogeneity? (1998) (0)
- Total purification ofa DNA-dependent ATPaseandof a DNA-binding protein fromhumancells (1983) (0)
- Activation of Human Immunodeficiency Virus-1 Transcription monitored by in vivo Footprinting of the Long Terminal Repeat. (1993) (0)
- Development of a competitive RT-PCR assay for the quantitative detection of gp91 gene expression in patients with chronic granulomatous disease (1994) (0)
- Effect of 6-(p-hydroxyphenylazo)-uracil on the homologous and heterologous transduction processes in Bacillus subtilis (1979) (0)
- Linkage ofFamilial Dilated Cardiomyopathy toChromosome9 (1995) (0)
- InVivoFootprinting Analysis ofConstitutive andInducible Protein-DNA Interactions attheLongTerminal Repeatof HumanImmunodeficiency VirusType1 (1993) (0)
- … though funding states have promised to pay up (2000) (0)
- Identification of start sites of bi-directional DNA synthesis at eukaryotic DNA replication origins. (2004) (0)
- The International Centre for Genetic Engineering and Biotechnology of UNIDO. (1990) (0)
- Functional recostitution of the NADPH oxidase activity in B-lymphoblasts from patients with X-linked CGD by retrovirus-mediated gene tranfer. (1994) (0)
- The HFSP Journal one year on: Moving forward with a new feature (2008) (0)
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