Arturo Zychlinsky
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Biologist
Arturo Zychlinsky's AcademicInfluence.com Rankings
Arturo Zychlinskybiology Degrees
Biology
#2674
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#4216
Historical Rank
Microbiology
#279
World Rank
#324
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Biology
Arturo Zychlinsky's Degrees
- PhD Microbiology University of Buenos Aires
Why Is Arturo Zychlinsky Influential?
(Suggest an Edit or Addition)According to Wikipedia, Arturo Zychlinsky is a biologist and since 2001 director at the Max Planck Institute for Infection Biology. His research focuses on Neutrophil Extracellular Traps which he discovered together with Volker Brinkmann, and the immune function of chromatin.
Arturo Zychlinsky's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neutrophil Extracellular Traps Kill Bacteria (2004) (7429)
- Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. (1999) (1683)
- Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps (2010) (1478)
- Novel cell death program leads to neutrophil extracellular traps. (2007) (1473)
- Neutrophil function: from mechanisms to disease. (2012) (1356)
- Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans (2009) (1344)
- Discrimination of bacterial lipoproteins by Toll-like receptor 6. (2001) (1343)
- Novel cell death program leads to neutrophil extracellular traps (2007) (1281)
- Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis (2010) (1194)
- Shigella flexneri induces apoptosis in infected macrophages (1992) (969)
- Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms (2006) (881)
- Beneficial suicide: why neutrophils die to make NETs (2007) (867)
- Neutrophil extracellular traps: Is immunity the second function of chromatin? (2012) (840)
- The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. (1999) (767)
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (2019) (627)
- NETs: a new strategy for using old weapons. (2009) (617)
- Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity. (2011) (574)
- An Endonuclease Allows Streptococcus pneumoniae to Escape from Neutrophil Extracellular Traps (2006) (570)
- Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation. (2011) (554)
- The apoptotic signaling pathway activated by Toll‐like receptor‐2 (2000) (535)
- Restoration of NET formation by gene therapy in CGD controls aspergillosis. (2009) (531)
- A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis (2014) (431)
- Diverse stimuli engage different neutrophil extracellular trap pathways (2017) (429)
- The induction of apoptosis by bacterial pathogens. (1999) (418)
- Shigella-induced Apoptosis Is Dependent on Caspase-1 Which Binds to IpaB* (1998) (412)
- Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation. (2000) (396)
- A bacterial invasin induces macrophage apoptosis by binding directly to ICE. (1996) (393)
- Gasdermin D plays a vital role in the generation of neutrophil extracellular traps (2018) (364)
- Extracellular ATP as a trigger for apoptosis or programmed cell death (1991) (343)
- Neutrophil elastase targets virulence factors of enterobacteria (2002) (322)
- Capsule and d‐alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps (2007) (309)
- Superoxide dismutase 1 regulates caspase-1 and endotoxic shock (2008) (295)
- Neutrophil Extracellular Traps: How to Generate and Visualize Them (2010) (268)
- Neutrophils: New insights and open questions (2018) (264)
- Bordetella pertussis induces apoptosis in macrophages: role of adenylate cyclase-hemolysin (1993) (263)
- Mutant superoxide dismutase 1-induced IL-1β accelerates ALS pathogenesis (2010) (263)
- Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease. (2010) (261)
- Toll-Like Receptors Are Temporally Involved in Host Defense (2004) (246)
- Caspase-1-Mediated Activation of Interleukin-1β (IL-1β) and IL-18 Contributes to Innate Immune Defenses against Salmonella enterica Serovar Typhimurium Infection (2006) (244)
- Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes. (1991) (236)
- Mouse Neutrophil Extracellular Traps in Microbial Infections (2009) (234)
- Salmonella Exploits Caspase-1 to Colonize Peyer's Patches in a Murine Typhoid Model (2000) (233)
- IpaB mediates macrophage apoptosis induced by Shigella flexneri (1994) (232)
- Pathogen‐induced apoptosis of macrophages: a common end for different pathogenic strategies (2000) (221)
- Perspectives series: host/pathogen interactions. Apoptosis in bacterial pathogenesis. (1997) (221)
- Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri. (1994) (219)
- A proposed role for neutrophil extracellular traps in cancer immunoediting (2013) (214)
- How do microbes evade neutrophil killing? (2006) (211)
- Neutrophil Elastase Enhances Sputum Solubilization in Cystic Fibrosis Patients Receiving DNase Therapy (2011) (206)
- Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death? (1997) (195)
- Neutrophil Extracellular Traps: The Biology of Chromatin Externalization. (2018) (195)
- In vivo apoptosis in Shigella flexneri infections (1996) (188)
- The balancing act of neutrophils. (2014) (175)
- Automatic quantification of in vitro NET formation (2013) (156)
- Cytolytic lymphocytes induce both apoptosis and necrosis in target cells. (1991) (149)
- Proinflammatory Effects of Bacterial Recombinant Human C-Reactive Protein Are Caused by Contamination With Bacterial Products, Not by C-Reactive Protein Itself (2005) (148)
- Apoptosis induced by bacterial pathogens. (1994) (147)
- How do neutrophils and pathogens interact? (2004) (147)
- The role of neutrophil extracellular traps in rheumatic diseases (2018) (137)
- The selC‐associated SHI‐2 pathogenicity island of Shigella flexneri (1999) (135)
- Apoptosis in Bacterial Pathogenesis (1996) (133)
- The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages (1997) (131)
- Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps. (2017) (122)
- MyD88, but Not Toll-Like Receptors 4 and 2, Is Required for Efficient Clearance of Brucella abortus (2005) (106)
- IpaB–IpgC interaction defines binding motif for type III secretion translocator (2009) (104)
- A Toll-like receptor 2–integrin β3 complex senses bacterial lipopeptides via vitronectin (2008) (100)
- Chronic granulomatous disease (CGD) and complete myeloperoxidase deficiency both yield strongly reduced dihydrorhodamine 123 test signals but can be easily discerned in routine testing for CGD. (2007) (92)
- Perspectives Series: Host/Pathogen Interactions (1997) (85)
- The regulation of apoptosis by microbial pathogens. (1999) (83)
- The regulatory protein PhoP controls susceptibility to the host inflammatory response in Shigella flexneri (2000) (83)
- Sepsis: the dark side of histones (2009) (82)
- The Neutrophil. (2021) (80)
- What is the role of Toll-like receptors in bacterial infections? (2007) (80)
- Human Neutrophils Kill Bacillus anthracis (2005) (80)
- Neutrophil extracellular traps drive inflammatory pathogenesis in malaria (2019) (80)
- Effects of low-intensity AC and/or DC electromagnetic fields on cell attachment and induction of apoptosis. (1997) (78)
- Do macrophages kill through apoptosis? (1996) (77)
- Protein refolding is required for assembly of the type three secretion needle (2010) (76)
- Shigella flexneri is trapped in polymorphonuclear leukocyte vacuoles and efficiently killed (1997) (76)
- Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages (2012) (72)
- Fungal and bacterial killing by neutrophils. (2009) (67)
- IcsA is a Shigella flexneri adhesin regulated by the type III secretion system and required for pathogenesis. (2014) (66)
- The cytosolic DNA sensor cGAS recognizes neutrophil extracellular traps (2021) (59)
- Genome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity (2016) (59)
- Acidic and basic fibroblast growth factors are survival factors with distinctive activity in quiescent BALB/c 3T3 murine fibroblasts. (1991) (59)
- Apoptosis in Acute Shigellosis Is Associated with Increased Production of Fas/Fas Ligand, Perforin, Caspase-1, and Caspase-3 but Reduced Production of Bcl-2 and Interleukin-2 (2002) (58)
- IpaB, a Shigella flexneri invasin, colocalizes with interleukin-1 beta-converting enzyme in the cytoplasm of macrophages (1997) (57)
- Structure-Function Analysis of theShigella Virulence Factor IpaB (2001) (57)
- Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis. (2015) (56)
- How bacteria initiate inflammation: aspects of the emerging story. (1998) (55)
- Immunodetection of NETs in Paraffin-Embedded Tissue (2016) (52)
- Release of Toll-Like Receptor-2-Activating Bacterial Lipoproteins in Shigella flexneri Culture Supernatants (2001) (51)
- Resistance of cytolytic lymphocytes to perforin-mediated killing. Lack of correlation with complement-associated homologous species restriction (1988) (50)
- Subcellular localization of perforin and serine esterase in lymphokine-activated killer cells and cytotoxic T cells by immunogold labeling. (1991) (49)
- Tripeptidyl Peptidase II Promotes Maturation of Caspase-1 in Shigella flexneri-Induced Macrophage Apoptosis (2000) (48)
- Neutrophil phenotypes and functions in cancer: A consensus statement (2022) (47)
- Macrophage apoptosis in microbial infections (1997) (45)
- Programmed cell death in infectious diseases. (1993) (43)
- Increased Interleukin-1 (IL-1) and Imbalance between IL-1 and IL-1 Receptor Antagonist during Acute Inflammation in Experimental Shigellosis (1999) (42)
- Interleukin-1 Antagonist Anakinra in Amyotrophic Lateral Sclerosis—A Pilot Study (2015) (41)
- Molecular and Cellular Mechanisms of Tissue Invasion by Shigella flexneri a (1994) (41)
- Neutrophil Extracellular Trap Formation Is Independent of De Novo Gene Expression (2016) (40)
- Induction and quantification of neutrophil extracellular traps. (2014) (40)
- Caspase-1 activation by Salmonella. (2003) (40)
- The ShiA protein encoded by the Shigella flexneri SHI‐2 pathogenicity island attenuates inflammation (2003) (38)
- Pathogenicity islands of Shigella. (2002) (38)
- The Capsule Sensitizes Streptococcus pneumoniae to α-Defensins Human Neutrophil Proteins 1 to 3 (2008) (37)
- Netting bacteria in sepsis (2007) (37)
- Beyond the grave: When is cell death critical for immunity to infection? (2016) (36)
- Shigella flexneri Phagosomal Escape Is Independent of Invasion (2007) (31)
- Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity (2015) (30)
- ShiA Abrogates the Innate T-Cell Response to Shigella flexneri Infection (2006) (29)
- Glutamate utilization promotes meningococcal survival in vivo through avoidance of the neutrophil oxidative burst (2011) (29)
- Copper Regulates the Canonical NLRP3 Inflammasome (2018) (28)
- Clinical isolates of Shigella species induce apoptosis in macrophages. (1997) (28)
- Resistance of cytolytic lymphocytes to perforin-mediated killing. Induction of resistance correlates with increase in cytotoxicity (1989) (28)
- Toll-like receptor-2 transduces signals for NF-κB activation, apoptosis and reactive oxygen species production (2001) (28)
- Neutrophil antimicrobial proteins enhance Shigella flexneri adhesion and invasion (2010) (27)
- Single residue determines the specificity of neutrophil elastase for Shigella virulence factors. (2008) (27)
- Introduction: Forum in immunology on neutrophils. (2003) (25)
- Molecular cellular microbiology (2002) (23)
- Cytotoxic mechanisms of murine lymphokine-activated killer cells: functional and biochemical characterization of homogeneous populations of spleen LAK cells. (1990) (23)
- Dnase1‐deficient mice spontaneously develop a systemic lupus erythematosus‐like disease (2018) (22)
- Tetrahydroisoquinolines: New Inhibitors of Neutrophil Extracellular Trap (NET) Formation (2017) (18)
- Toll-like receptor-2 transduces signals for NF-kappa B activation, apoptosis and reactive oxygen species production. (2001) (16)
- The bacterial pigment pyocyanin inhibits the NLRP3 inflammasome through intracellular reactive oxygen and nitrogen species (2018) (14)
- O-Antigen Protects Gram-Negative Bacteria from Histone Killing (2013) (13)
- Apoptosis as a trigger of inflammation in Shigella-induced cell death. (1996) (12)
- A homogeneous population of lymphokine-activated killer (LAK) cells is incapable of killing virus-, bacteria-, or parasite-infected macrophages. (1990) (11)
- Sensing, presenting, and regulating PAMPs. (2007) (10)
- Cytolytic mechanisms of the immune system. (1988) (9)
- Induction of apoptosis by microbial pathogens. (2004) (9)
- Linker histone H1.2 and H1.4 affect the neutrophil lineage determination (2019) (9)
- The ipaB gene of Shigella flexneri and macrophage-programmed cell death. (1993) (6)
- Histone H3 clipping is a novel signature of human neutrophil extracellular traps (2021) (4)
- Methods for studying bacteria-induced host cell death (2002) (4)
- Protecting against Aspergillus infection in CGD (2009) (3)
- Response: Protecting against Aspergillus infection in CGD (2009) (3)
- Virulence mechanisms of bacterial pathogens: edited by J.A. Roth, C.A. Bolin, K.A. Brogden, F.C. Minion and M.J. Wannemuehler ASM Press, 1995. £52.50 hbk (xvii + 366 pages) ISBN 1 55581 085 3 (1996) (2)
- Author response: Diverse stimuli engage different neutrophil extracellular trap pathways (2017) (2)
- Apoptosis and Enteric Bacterial Infections (2003) (2)
- Host-microbe interactions: bacteria Microbes and their hosts: mutual interactions (2002) (1)
- aspergillosis Restoration of NET formation by gene therapy in CGD controls (2009) (1)
- Interleukin I IsReleased byMurineMacrophagesduringApoptosis Inducedby Shigella flexneri (1994) (1)
- Protecting against Aspergillus infection in CGD Response (2009) (1)
- Editorial Board: Eur. J. Immunol. 10'16 (2016) (0)
- SP0140 Neutrophil extracellular traps (2013) (0)
- Neutrophil Extracellular Traps (NETs) -- from infection to autoimmunity (2012) (0)
- Large granular lymphocyte (1992) (0)
- Brief report Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease (2010) (0)
- Antimicrobial Mechanisms of Neutrophils (2010) (0)
- Apoptosis in Shigella and Salmonella Infections (2003) (0)
- Arturo Zychlinsky Infection Shigella flexneri to ShiA Abrogates the Innate T-Cell Response (2006) (0)
- Crystal structure of IpgC from Shigella flexneri (2009) (0)
- Involvement of the selected genes in the colanic acid pathway and cloning under arabinose promoter. (2013) (0)
- , Bärbel Raupach and Independent of Invasion Phagosomal Escape Is Shigella flexneri (2007) (0)
- Entering the neutrophil trap (2021) (0)
- Crystal structure of a soluble PrgI mutant from Salmonella Typhimurium (2010) (0)
- Apoptose, interleukine et shigellose (1995) (0)
- Editorial Board: Eur. J. Immunol. 10'15 (2015) (0)
- Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL+-Staphylococcus aureus infections (2022) (0)
- Editorial Board: Eur. J. Immunol. 12'16 (2016) (0)
- PS5:92 Clarification of the role of dnase 1 on the onset of systemic lupus erythematosus in a murine model (2018) (0)
- Patients with recurrent PVL+-Staphylococcus aureus infections show enhanced sensitivity to PVL-mediated formation of atypical NETs (2021) (0)
- Crystal structure of IpgC in complex with the chaperone binding region of IpaB (2009) (0)
- Linker Histone H1 subtypes specifically regulate neutrophil differentiation (2019) (0)
- Rotation Invariant Clustering of 3D Cell Nuclei Shapes * (2019) (0)
- Basic science under threat: Lessons from the Skirball Institute (2022) (0)
- Editorial Board: Eur. J. Immunol. 1'17 (2017) (0)
- Lipoproteins and recognition by toll-like receptors (2000) (0)
- Shigella host cell invasion: significance in pathogenesis (1999) (0)
- Methods in microbiology (2016) (0)
- Novel binding domain defines stoichiometry between type III secretion systm chaperone IpgC and its substrates IpaB and IpaC (2009) (0)
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Arturo Zychlinsky is affiliated with the following schools:
