Arun K Shukla
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Arun K Shuklacomputer-science Degrees
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Computational Linguistics
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Machine Learning
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Computer Science
Arun K Shukla's Degrees
- PhD Computer Science University of California, Berkeley
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science Stanford University
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(Suggest an Edit or Addition)Arun K Shukla's Published Works
Published Works
- Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors. (2012) (559)
- Distinct Phosphorylation Sites on the β2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin (2011) (549)
- Visualization of arrestin recruitment by a G Protein-Coupled Receptor (2014) (421)
- Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling. (2011) (406)
- GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling (2016) (390)
- Functional specialization of β-arrestin interactions revealed by proteomic analysis (2007) (389)
- Structure of active β-arrestin1 bound to a G protein-coupled receptor phosphopeptide (2013) (367)
- Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis (2017) (248)
- Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors (2008) (240)
- Multiple ligand-specific conformations of the β2-adrenergic receptor. (2011) (239)
- beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. (2009) (212)
- Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) (2010) (187)
- Methodological advances: the unsung heroes of the GPCR structural revolution (2015) (180)
- β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2 (2009) (144)
- Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation* (2007) (128)
- Functional competence of a partially engaged GPCR–β-arrestin complex (2016) (123)
- β-Arrestin–dependent activation of Ca2+/calmodulin kinase II after β1–adrenergic receptor stimulation (2010) (119)
- Emerging Functional Divergence of β-Arrestin Isoforms in GPCR Function (2015) (117)
- Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor (2020) (109)
- Development of a nanocomposite ultrafiltration membrane based on polyphenylsulfone blended with graphene oxide (2017) (108)
- Mg3Sb2-based Zintl compound: a non-toxic, inexpensive and abundant thermoelectric material for power generation (2013) (107)
- Emerging structural insights into biased GPCR signaling. (2014) (97)
- Topical delivery of clobetasol propionate loaded microemulsion based gel for effective treatment of vitiligo: ex vivo permeation and skin irritation studies. (2013) (97)
- Arresting a Transient Receptor Potential (TRP) Channel (2010) (94)
- The structure of the neuropeptide bradykinin bound to the human G-protein coupled receptor bradykinin B2 as determined by solid-state NMR spectroscopy. (2008) (87)
- Novel Structural Insights into GPCR-β-Arrestin Interaction and Signaling. (2017) (83)
- Molecular mechanism of modulating arrestin conformation by GPCR phosphorylation (2018) (77)
- Removal of heavy metal ions using a carboxylated graphene oxide-incorporated polyphenylsulfone nanofiltration membrane (2018) (75)
- Emerging Approaches to GPCR Ligand Screening for Drug Discovery. (2015) (71)
- Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation (2017) (65)
- Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor (2013) (58)
- Comparative investigation of CuFe 2 O 4 nano and microstructures for structural, morphological, optical and magnetic properties (2016) (47)
- Conformational sensors and domain-swapping reveal structural and functional differences between β-arrestin isoforms (2019) (44)
- Biasing GPCR Signaling from Inside (2014) (43)
- Illuminating GPCR Signaling by Cryo-EM. (2018) (40)
- Graphene boosts thermoelectric performance of a Zintl phase compound (2015) (38)
- Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling (2020) (37)
- Emerging Insights into the Structure and Function of Complement C5a Receptors. (2020) (37)
- Evaluation of antibacterial and antifouling properties of silver-loaded GO polysulfone nanocomposite membrane against Escherichia coli, Staphylococcus aureus, and BSA protein (2019) (37)
- Green synthesis and antifungal activity of Al2O3 NPs against fluconazole-resistant Candida spp isolated from a tertiary care hospital (2016) (36)
- Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors (2021) (35)
- Key phosphorylation sites in GPCRs orchestrate the contribution of β‐Arrestin 1 in ERK1/2 activation (2020) (35)
- The Complement C5a-C5aR1 GPCR Axis in COVID-19 Therapeutics (2020) (33)
- A synthetic intrabody based selective and generic inhibitor of GPCR endocytosis (2017) (33)
- Selective ion removal and antibacterial activity of silver-doped multi-walled carbon nanotube / polyphenylsulfone nanocomposite membranes (2019) (33)
- Community guidelines for GPCR ligand bias: IUPHAR review 32 (2022) (33)
- Effect of doping concentration and annealing temperature on luminescence properties of Y2O3:Eu3+ nanophosphor prepared by colloidal precipitation method (2012) (33)
- Removal of Cadmium and Chromium by Mixture of Silver Nanoparticles and Nano-Fibrillated Cellulose Isolated from Waste Peels of Citrus Sinensis (2021) (31)
- Thin-Film Nanocomposite Membrane Incorporated with Porous Zn-Based Metal-Organic Frameworks: Toward Enhancement of Desalination Performance and Chlorine Resistance. (2021) (31)
- A crystal clear view of the β2-adrenergic receptor (2008) (30)
- Atomic layer deposition of TiO2 film on a polyethersulfone membrane: separation applications (2016) (30)
- Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors. (2018) (29)
- Effect of foliar application of calcium and boron on growth, productivity and quality of Indian gooseberry (Emblica officinalis) (2011) (28)
- Heterologous expression and comparative characterization of the human neuromedin U subtype II receptor using the methylotrophic yeast Pichia pastoris and mammalian cells. (2007) (28)
- GPCR Signaling: β-arrestins Kiss and Remember (2016) (28)
- Biased ligands at opioid receptors: Current status and future directions (2021) (27)
- Crystallizing Thinking about the β2-Adrenergic Receptor (2008) (27)
- k-Carrageenan – A versatile biopolymer for the preparation of a hydrophilic PVDF composite membrane (2019) (25)
- Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide. (2020) (25)
- Synthesis and Investigations on Microwave Absorption Properties of Core–Shell FeCo(C) Alloy Nanoparticles (2014) (24)
- Graphene oxide, an effective nanoadditive for a development of hollow fiber nanocomposite membrane with antifouling properties (2018) (24)
- Antimicrobial and antifouling properties of versatile PPSU/carboxylated GO nanocomposite membrane against Gram-positive and Gram-negative bacteria and protein (2018) (22)
- Biochemical and pharmacological characterization of the human bradykinin subtype 2 receptor produced in mammalian cells using the Semliki Forest virus system (2006) (22)
- Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells (2006) (22)
- Synthesis, characterization and optical properties of sulfur and fluorine doped ZnO nanostructures for visible light utilized catalysis (2017) (22)
- Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors (2008) (21)
- Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells. (2006) (20)
- Partial ligand-receptor engagement yields functional bias at the human complement receptor, C5aR1 (2019) (20)
- Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G-protein–coupled receptors (2020) (20)
- Phytoremediation of dairy wastewater using Azolla pinnata: Application of image processing technique for leaflet growth simulation (2021) (19)
- Preparation and Characterization of Biocompatible and Water-Dispersible Superparamagnetic Iron Oxide Nanoparticles (SPIONs) (2010) (19)
- Topical delivery of clobetasol propionate loaded microemulsion based gel for effective treatment of vitiligo--part II: rheological characterization and in vivo assessment through dermatopharmacokinetic and pilot clinical studies. (2014) (19)
- Electron microscopic ultrastructural study on the toxicological effects of AgNPs on the liver, kidney and spleen tissues of albino mice. (2016) (18)
- Heterologous expression and characterization of the recombinant bradykinin B2 receptor using the methylotrophic yeast Pichia pastoris. (2007) (18)
- Tuning of Microwave Absorption Properties and Electromagnetic Interference (EMI) Shielding Effectiveness of Nanosize Conducting Black-Silicone Rubber Composites Over 8-18 GHz (2017) (17)
- Functional overexpression and characterization of human bradykinin subtype 2 receptor in insect cells using the baculovirus system (2006) (16)
- SnapShot: GPCR-Ligand Interactions (2014) (15)
- Terminating G-Protein Coupling: Structural Snapshots of GPCR-β-Arrestin Complexes (2020) (15)
- Innovation of novel ‘Tab in Tab’ system for release modulation of milnacipran HCl: optimization, formulation and in vitro investigations (2013) (15)
- Transformation of hazardous sacred incense sticks ash waste into less toxic product by sequential approach prior to their disposal into the water bodies (2021) (15)
- GPCR Signaling: The Interplay of Gαi and β-arrestin (2018) (15)
- Silver nanoparticle/r-graphene oxide deposited mesoporous-manganese oxide nanocomposite for pollutant removal and supercapacitor applications (2017) (15)
- Synthesis of Fe3O4@Y2O3:Eu3+ core–shell multifunctional nanoparticles and their magnetic and luminescence properties (2013) (14)
- Rec A-independent homologous recombination induced by a putative fold-back tetraplex DNA (2006) (14)
- A Facile Approach for Elimination of Electroneutral/Anionic Organic Dyes from Water Using a Developed Carbon-Based Polymer Nanocomposite Membrane (2020) (14)
- Measuring surface expression and endocytosis of GPCRs using whole-cell ELISA. (2019) (14)
- Sensitive and selective detection of copper ions using low cost nitrogen doped carbon quantum dots as a fluorescent sensing plateform (2017) (13)
- A Novel Approach to Optimize the Fabrication Conditions of Thin Film Composite RO Membranes Using Multi-Objective Genetic Algorithm II (2020) (13)
- Studies on Native Medicinal Plants, I. The Quaternary Alkaloids of Thalictrum javanicum (1983) (12)
- Biased Opioid Receptor Ligands: Gain without Pain (2017) (12)
- Dye Separation and Antibacterial Activities of Polyaniline Thin Film-Coated Poly(phenyl sulfone) Membranes (2020) (11)
- Antibody fragments for stabilization and crystallization of G protein-coupled receptors and their signaling complexes. (2015) (11)
- Efficient soluble anionic dye removal and antimicrobial properties of ZnO embedded‐ Polyphenylsulfone membrane (2020) (11)
- Fabrication of different SnO2 nanorods for enhanced photocatalytic degradation and antibacterial activity (2021) (10)
- Structure and function of β-arrestins, their emerging role in breast cancer, and potential opportunities for therapeutic manipulation. (2020) (10)
- Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi (2012) (9)
- Frozen in action: cryo-EM structure of a GPCR–G-protein complex (2017) (9)
- Development and Validation of UV Spectrophotometric Method for Determination of Milnacipran in bulk and Pharmaceutical Dosage Form (2011) (9)
- A highly permeable zinc-based MOF/polyphenylsulfone composite membrane with elevated antifouling properties. (2020) (8)
- In vivo performance evaluation and establishment of IVIVC for osmotic pump based extended release formulation of milnacipran HCl (2013) (8)
- κ-Carrageenan as a promising pore-former for the preparation of a highly porous polyphenylsulfone membrane (2017) (8)
- Development of Platform Technology for Oral Controlled Delivery of Highly Water Soluble Drugs Using Milnacipran HCl as a Model Drug (2012) (7)
- Measuring agonist-induced ERK MAP kinase phosphorylation for G-protein-coupled receptors. (2019) (7)
- Structural insights into ligand recognition and activation of angiotensin receptors. (2021) (7)
- Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR (2021) (7)
- Design and characterization of ofloxacin mucoadhesive in situ hydrogel (2012) (6)
- Simple Route for Synthesis of Multilayer Graphene Nanoballs by Flame Combustion of Edible Oil (2013) (6)
- Chemical and Synthetic Approaches in Membrane Biology (2017) (5)
- Emerging structural insights into GPCR-β-arrestin interaction and functional outcomes. (2022) (5)
- A clarification on the use of the term viscin thread in Orchidaceae (1984) (5)
- Genetic Resources of Aonla (Emblica of ficinalis Gaertn.) (2005) (4)
- Development and characterization of Telmisartan self-microemulsifying drug delivery system for bioavailability enhancement (2015) (4)
- Membrane proteins : engineering, purification and crystallization (2015) (4)
- Emerging paradigms in activation, signaling, and regulation of G protein‐coupled receptors (2021) (4)
- Evaluation of aonla germplasm for growth, yield and quality attributes in hot arid ecosystem. (2010) (4)
- The Inside Story: Crystal Structure of the Chemokine Receptor CCR7 with an Intracellular Allosteric Antagonist. (2019) (4)
- From Recombinant Expression to Crystals: A Step-by-Step Guide to GPCR Crystallography. (2015) (4)
- Polysulfone–poly(Orthotoluidine) nanocomposite membrane with an improved separation performance (2017) (3)
- A palindromic repeat sequence adopts a stable fold back structure under supercoiling. (2006) (3)
- Methods of Screening-Purification and Antimicrobial Potentialities of Bacteriocin in Health Care. (2017) (3)
- Structural Basis of Partial Agonism at the β2-Adrenergic Receptor. (2018) (3)
- Role of changing climate on chilling unit accumulation and yield for apple (Malus × domestica Borkh) cultivation at Shimla, Himachal Pradesh, India. (2015) (3)
- Bacilli as Biological Nano-factories Intended for Synthesis of Silver Nanoparticles and Its Application in Human Welfare (2017) (3)
- Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody (2022) (3)
- Evaluation of ber (Ziziphus mauritiana L.) cultivars under hot arid ecosystem of Rajasthan (2007) (3)
- Membrane proteins : production and functional characterization (2015) (3)
- Screening of American Cotton (Gossypium hirsutum L.) and Desi Cotton (G. arboreum) for Fibre Quality Traits, Seed Cotton Yield and Important Yield Components (2006) (3)
- Recent Advancements in Polyphenylsulfone Membrane Modification Methods for Separation Applications (2022) (3)
- The Gut Feeling: GPCRs Enlighten the Way. (2019) (3)
- Performance of Indian gooseberry (Emblica officinalis) cultivars under arid region of India (2009) (3)
- Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor (2020) (3)
- Site-directed labeling of β-arrestin with monobromobimane for measuring their interaction with G protein-coupled receptors. (2020) (2)
- Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system (2022) (2)
- Release modulation of highly water soluble drug using solid dispersion: impact of dispersion and its compressed unit (2014) (2)
- Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex. (2020) (2)
- Calcium as a biased cofactor (2020) (2)
- Innentitelbild: The Structure of the Neuropeptide Bradykinin Bound to the Human G‐Protein Coupled Receptor Bradykinin B2 as Determined by Solid‐State NMR Spectroscopy (Angew. Chem. 9/2008) (2008) (2)
- An intrabody sensor to monitor conformational activation of β-arrestins. (2022) (2)
- Design, Development and Optimization Aceclofenac Effervescence tablets by Central Composite Design (2015) (2)
- Purification of native CCL7 and its functional interaction with selected chemokine receptors (2019) (2)
- Reversible biotinylation of purified proteins for measuring protein-protein interactions. (2020) (1)
- Structural insights into ligand-recognition, activation, and signaling-bias at the complement C5a receptor, C5aR1 (2023) (1)
- Mg 3 Sb 2-based Zintl compound : a non-toxic , inexpensive and abundant thermoelectric material for power generation 3 (2013) (1)
- Structural snapshots uncover a lock-and-key type conserved activation mechanism of β-arrestins by GPCRs (2022) (1)
- G Protein-Coupled Receptors (GPCRs). (2016) (1)
- Recent Advances in Preparation and Characterization of Graphene-Based Nanocomposite Membranes for Water Purification (2020) (1)
- Performance of Lentil (Lens Culinaris) Verities to Different Level of Sulphur Under Rainfed Condition District of Chitrakoot UP (2014) (1)
- Role of Viruses in Nanoparticles Synthesis (2021) (1)
- Crystal structure of active Beta‐arrestin1 bound to phosphorylated carboxy‐terminus of a G protein‐coupled receptor (2013) (1)
- Editorial overview: Multi-protein assemblies in signaling. (2016) (1)
- Probing the surface ultrastructure of Brevibacillus laterosporus using atomic force microscopy. (2020) (1)
- Effect of severity and time of pruning on canopy growth and yield of ber (Ziziphus mauritiana Lamk) under hot arid ecosystem (2007) (1)
- Performance evaluation of aonla (Emblica officinalis Gaertn.) for flowering behaviour in arid region (2008) (0)
- Single-molecule analysis of receptor-β-arrestin interactions in living cells (2022) (0)
- Faculty Opinions recommendation of A forward chemical genetic screen reveals gut microbiota metabolites that modulate host physiology. (2019) (0)
- Contents Silver Spoons and Other Personal Reflections (2013) (0)
- Making the switch: The role of Gq in driving GRK selectivity at GPCRs (2022) (0)
- Feeling at home: Structure of the NTSR1–Gi complex in a lipid environment (2021) (0)
- Structural insights into agonist-binding and activation of the human complement C3a receptor (2023) (0)
- Faculty Opinions recommendation of GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors. (2019) (0)
- In-cellulo chemical cross-linking to visualize protein-protein interactions. (2022) (0)
- Synthesis and Microwave Absorption Property of the Core-shell Absorber with Hollow Cenosphere as Core (2012) (0)
- Faculty Opinions recommendation of In vivo brain GPCR signaling elucidated by phosphoproteomics. (2018) (0)
- Faculty Opinions recommendation of β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. (2020) (0)
- Targeting the cell's gatekeepers for novel drug discovery (2022) (0)
- Structural snapshot of a β-arrestin-biased receptor. (2022) (0)
- Faculty Opinions recommendation of Structural determinants of 5-HT2B receptor activation and biased agonism. (2018) (0)
- Establish a Barcode That Encodes Differential Functions of { beta }-Arrestin Distinct Phosphorylation Sites on the { beta } 2-Adrenergic Receptor ` (2011) (0)
- Entering the Pocket: Crystal Structure of a Prostaglandin D2 Receptor. (2018) (0)
- Effect of soil amendments on growth characteristics of apple (Malus × domestica) cv. Starking Delicious. (2015) (0)
- Faculty Opinions recommendation of In vivo mapping of a GPCR interactome using knockin mice. (2020) (0)
- A NOVEL ELECTROPHORETIC EPOXY-MONTMORILLONITE (EMNC) NANOCOMPOSITE # FOR DIELECTRIC APPLICATION (2015) (0)
- Performance of apricot (Prunus armeniaca L.) varieties for growth, yield and quality traits. (2015) (0)
- Scratching the itch with cryo-EM (2022) (0)
- Design and characterization of ofloxacin mucoadhesi ve in situ hydrogel (2012) (0)
- Crystal structure of β-arrestin 2 in complex with an atypical chemokine receptor phosphopeptide reveals an alternative active conformation (2019) (0)
- Faculty Opinions recommendation of aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis. (2021) (0)
- Backbone structure of bradykinin (BK) peptide bound to human Bradykinin 2 Receptor (B2R) determined by MAS SSNMR (2018) (0)
- Faculty of 1000 evaluation for Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. (2018) (0)
- thermoelectric performance of a Zintl phase compound † (2015) (0)
- Faculty Opinions recommendation of Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function. (2020) (0)
- A key GPCR phosphorylation motif discovered in arrestin2•CCR5 phosphopeptide complexes (2022) (0)
- [beta]‐arrestin 1 mediates angiotensin II induced ubiquitination and down‐regulation of TRPV4 (2009) (0)
- Faculty Opinions recommendation of Functional map of arrestin-1 at single amino acid resolution. (2014) (0)
- Role Of Packaging Materials And Saline Solutions On Shelf Life Of Paneer Prepared With Different Types Of Milk And Fat Levels (2006) (0)
- Faculty of 1000 evaluation for Yeast surface display platform for rapid discovery of conformationally selective nanobodies. (2018) (0)
- Resonating with the signaling bias of CXCR7. (2022) (0)
- Cellular Signalling - Special issue to celebrate 75th birthday of Prof. Robert J. Lefkowitz. (2018) (0)
- Faculty Opinions recommendation of Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity. (2019) (0)
- Genetically encoded intrabody sensors illuminate structural and functional diversity in GPCR-β-arrestin complexes (2019) (0)
- Faculty Opinions recommendation of Nanobody-enabled monitoring of kappa opioid receptor states. (2020) (0)
- A Simplified Schematic Representation of Cell-based High-Throughput Screening ( HTS ) , Structure-based and Sensor-based Ligand Discovery Approaches (2015) (0)
- Method of making an asymmetric polyvinylidene difluoride membrane (2019) (0)
- A streamlined protocol for expression and purification of wild-type β-arrestins. (2023) (0)
- Molecular mechanism of modulating arrestin conformation by GPCR phosphorylation (2018) (0)
- Membrane proteins--engineering, purification and crystallization. Preface. (2015) (0)
- Plasma membrane preassociation drives β-arrestin coupling to receptors and activation (2023) (0)
- ASMS 2007, Poster# 438: Desalting Phosphopeptides by Solid-Phase Extraction (2007) (0)
- Faculty Opinions recommendation of G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons. (2018) (0)
- Faculty Opinions recommendation of Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation. (2018) (0)
- Faculty Opinions recommendation of Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors. (2017) (0)
- Backbone structure of free bradykinin (BK) in DDM/CHS detergent micelle determined by MAS SSNMR (2018) (0)
- Faculty Opinions recommendation of Structure and dynamics of the active human parathyroid hormone receptor-1. (2019) (0)
- Faculty Opinions recommendation of Phosphorylation barcode-dependent signal bias of the dopamine D1 receptor. (2020) (0)
- Faculty Opinions recommendation of Structural basis of the diversity of adrenergic receptors. (2019) (0)
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What Schools Are Affiliated With Arun K Shukla?
Arun K Shukla is affiliated with the following schools: