Asifa Akhtar
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Asifa Akhtarbiology Degrees
Biology
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Molecular Biology
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Genetics
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Biology
Asifa Akhtar's Degrees
- Masters Biochemistry University of Karachi
Why Is Asifa Akhtar Influential?
(Suggest an Edit or Addition)According to Wikipedia, Asifa Akhtar is a Pakistani biologist who has made significant contributions to the field of chromosome regulation. She is Senior Group Leader and Director of the Department of Chromatin Regulation at the Max Planck Institute of Immunobiology and Epigenetics. Akhtar was awarded EMBO membership in 2013. She became the first international and female Vice President of the Max Planck Society's Biology and Medicine Section in July 2020.
Asifa Akhtar's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila. (2000) (472)
- High-resolution TADs reveal DNA sequences underlying genome organization in flies (2017) (460)
- The nuclear envelope and transcriptional control (2007) (457)
- Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. (2006) (410)
- Chromodomains are protein–RNA interaction modules (2000) (383)
- DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome (2017) (353)
- Considerations when investigating lncRNA function in vivo (2014) (307)
- hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells (2005) (290)
- Nuclear Pore Proteins Nup153 and Megator Define Transcriptionally Active Regions in the Drosophila Genome (2010) (245)
- Dosage compensation in Drosophila melanogaster: epigenetic fine-tuning of chromosome-wide transcription (2012) (237)
- The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition (2001) (180)
- Genome-wide Analysis Reveals MOF as a Key Regulator of Dosage Compensation and Gene Expression in Drosophila (2008) (175)
- The dMi‐2 chromodomains are DNA binding modules important for ATP‐dependent nucleosome mobilization (2002) (161)
- The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma (2008) (156)
- The nonspecific lethal complex is a transcriptional regulator in Drosophila. (2010) (148)
- Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila. (2013) (144)
- Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification (2014) (134)
- Rapid evolutionary turnover underlies conserved lncRNA–genome interactions (2016) (133)
- Functional integration of the histone acetyltransferase MOF into the dosage compensation complex (2004) (123)
- Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing (2009) (115)
- MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria (2016) (106)
- Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1 (2011) (97)
- X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. (2006) (97)
- The many lives of KATs — detectors, integrators and modulators of the cellular environment (2018) (96)
- The NSL Complex Regulates Housekeeping Genes in Drosophila (2012) (95)
- NMR Structure of the First PHD Finger of Autoimmune Regulator Protein (AIRE1) (2005) (91)
- Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex (2014) (91)
- Modulation of cellular processes by histone and non-histone protein acetylation (2022) (91)
- MOF-regulated acetylation of MSL-3 in the Drosophila dosage compensation complex. (2003) (85)
- MOF-associated complexes ensure stem cell identity and Xist repression (2014) (84)
- Dosage Compensation of the X Chromosome: A Complex Epigenetic Assignment Involving Chromatin Regulators and Long Noncoding RNAs. (2018) (79)
- Transcription-Coupled Methylation of Histone H3 at Lysine 36 Regulates Dosage Compensation by Enhancing Recruitment of the MSL Complex in Drosophila melanogaster (2008) (79)
- Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters (2012) (77)
- Dosage compensation: an intertwined world of RNA and chromatin remodelling. (2003) (69)
- The MOF chromobarrel domain controls genome-wide H4K16 acetylation and spreading of the MSL complex. (2012) (69)
- High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila. (2015) (67)
- Cotranscriptional recruitment of the dosage compensation complex to X-linked target genes. (2007) (65)
- Distinct activated and non‐activated RNA polymerase II complexes in yeast. (1996) (61)
- The right dose for every sex (2006) (61)
- Structure of the Chromo Barrel Domain from the MOF Acetyltransferase* (2005) (58)
- Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation (2020) (55)
- Multiple facets of nuclear periphery in gene expression control. (2011) (52)
- An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis (2015) (51)
- roX RNAs: Non-coding regulators of the male X chromosome in flies (2009) (50)
- The MSL complex: juggling RNA-protein interactions for dosage compensation and beyond. (2015) (48)
- The NSL complex maintains nuclear architecture stability via lamin A/C acetylation (2019) (47)
- MOF maintains transcriptional programs regulating cellular stress response (2015) (45)
- Msl1-mediated dimerization of the dosage compensation complex is essential for male X-chromosome regulation in Drosophila. (2012) (40)
- X‐chromosome targeting and dosage compensation are mediated by distinct domains in MSL‐3 (2006) (34)
- The MSL complex: X chromosome and beyond. (2010) (31)
- A general precursor ion‐like scanning mode on quadrupole‐TOF instruments compatible with chromatographic separation (2006) (31)
- CAPRI enables comparison of evolutionarily conserved RNA interacting regions (2019) (30)
- The Epigenome Network of Excellence (2005) (29)
- Functional mechanisms and abnormalities of the nuclear lamina (2021) (29)
- The non‐specific lethal (NSL) complex at the crossroads of transcriptional control and cellular homeostasis (2019) (29)
- Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling (2019) (28)
- Systematic Identification of Cell-Cell Communication Networks in the Developing Brain (2019) (28)
- Drosophila dosage compensation (2011) (27)
- X chromosomal regulation in flies: when less is more (2009) (27)
- RNA nucleation by MSL2 induces selective X chromosome compartmentalization (2020) (24)
- De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation (2018) (24)
- Epigenetic Regulators as the Gatekeepers of Hematopoiesis. (2020) (24)
- uvCLAP is a fast and non-radioactive method to identify in vivo targets of RNA-binding proteins (2018) (22)
- Domain ChIRP reveals the modularity of long noncoding RNA architecture, chromatin interactions, and function (2014) (21)
- Chromatin mechanisms in Drosophila dosage compensation. (2005) (21)
- Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration (2021) (20)
- Response to Comments on “Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters” (2013) (20)
- A mutually exclusive stem–loop arrangement in roX2 RNA is essential for X-chromosome regulation in Drosophila (2017) (20)
- A decade of molecular cell biology: achievements and challenges (2011) (20)
- Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells (2018) (19)
- Drosophila MCRS2 Associates with RNA Polymerase II Complexes To Regulate Transcription (2010) (19)
- Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature (2020) (18)
- Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation (2016) (17)
- The non‐specific lethal (NSL) complex at the crossroads of transcriptional control and cellular homeostasis (2019) (14)
- MAPCap allows high-resolution detection and differential expression analysis of transcription start sites (2019) (14)
- Pyrido- and benzisothiazolones as inhibitors of histone acetyltransferases (HATs) (2014) (14)
- NMR structure of the first phd finger of autoimmune regulator protein (AIRE1): insights into apeced (2005) (12)
- Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation (2020) (12)
- FLASH: ultra-fast protocol to identify RNA–protein interactions in cells (2019) (11)
- The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise (2019) (11)
- Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate (2020) (7)
- Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cells (2021) (7)
- Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice (2021) (7)
- Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and Drosophila (2021) (6)
- Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules (2020) (6)
- Functional interplay between MSL 1 and CDK 7 controls RNA polymerase II Ser 5 phosphorylation (2016) (5)
- Large-scale nuclear architecture and transcriptional control. (2011) (5)
- Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. (2020) (5)
- Considerations when investigating lncRNA function (2014) (4)
- Cofactor Analogues as Active Site Probes in Lysine Acetyltransferases. (2019) (4)
- In and around the nucleus (2006) (3)
- Abstract 12851: Efficacy and Safety of Rilonacept in Recurrent Pericarditis: A Multicenter Phase 2 Clinical Trial (2019) (3)
- uvCLAP: a fast, non-radioactive method to identify in vivo targets of RNA-binding proteins (2017) (2)
- Author response: MOF-associated complexes ensure stem cell identity and Xist repression (2014) (1)
- Explorer Considerations when investigating lncRNA function in vivo (2014) (1)
- 3029 – TEMPORAL EXPRESSION OF MOF ACETYLTRANSFERASE PRIMES TRANSCRIPTION FACTOR NETWORKS FOR ERYTHROID FATE (2020) (0)
- New TeAM, New ideAS (2020) (0)
- Author response: Considerations when investigating lncRNA function in vivo (2014) (0)
- The solution structure of the chromo barrel domain from the males- absent on the first (MOF) protein. (2005) (0)
- Design and Application of Cofactor Analogues as Chemical Tools to Probe Lysine Acetyltransferase Ligands Targeting the Catalytic Domain (2018) (0)
- Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice (2021) (0)
- CAPRI enables comparison of evolutionarily conserved RNA interacting regions (2019) (0)
- Epigenetic regulation of the X chromosome (471.1) (2014) (0)
- Author Correction: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation (2023) (0)
- High-resolution TADs reveal DNA sequences underlying genome organization in flies (2018) (0)
- MAPCap: A fast and quantitative transcription start site profiling protocol (2019) (0)
- 1 uvCLAP : a fast , non-radioactive method to identify in vivo targets of RNA-binding proteins (2017) (0)
- 2018 - TRANSPOSABLE ELEMENTS ENHANCE HEMATOPOIETIC REGENERATION VIA ACTIVATION OF INNATE IMMUNE SIGNALLING (2019) (0)
- How Does the Enzyme MOF Work as a Molecular Bridge between Epigenetics and Metabolism (2017) (0)
- The many lives of KATs — detectors, integrators and modulators of the cellular environment (2018) (0)
- MOF, an Acetyl Transferase Involved in Dosage Compensation in Drosophila, Uses a CCHC Finger for Substrate Recognition (2005) (0)
- Finding your way through the science maze (2018) (0)
- De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation (2018) (0)
- RNA nucleation by MSL2 induces selective X chromosome compartmentalization (2020) (0)
- Epigenetics-Exploring the Genome Project (2017) (0)
- uvCLAP is a fast and non-radioactive method to identify in vivo targets of RNA-binding proteins (2018) (0)
- Christiane melanogaster Drosophila of the MSL Complex in Compensation by Enhancing Recruitment Histone H 3 at Lysine 36 Regulates Dosage Transcription-Coupled Methylation of (2008) (0)
- The nucleus and gene expression: the center of the cyclone. (2012) (0)
- Repetitive Elements Enhance Hematopoietic Regeneration Via Activation of the Innate Immune Receptor MDA5 (2019) (0)
- Evolutionary dynamics of roX lncRNA function and genomic occupancy (2015) (0)
- Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells (2018) (0)
- Epigenetics for big and small (2007) (0)
- Asifa Akhtar (2023) (0)
- Finding your way through the science maze (2018) (0)
- The NSL complex mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise (2018) (0)
- Publisher Correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration (2021) (0)
- Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature (2020) (0)
- Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation (2020) (0)
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