Augustine M. K. Choi

Augustine M. K. Choi's AcademicInfluence.com Rankings

Philosophy

#5093

World Rank

#7816

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#2426

World Rank

#3416

Historical Rank

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Philosophy

Augustine M. K. Choi's Degrees

Doctorate Medicine University of Chicago
PhD Biochemistry University of Chicago

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Augustine M. K. Choi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. (2011) (2168)
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. (2006) (2125)
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway (2000) (2032)
Nrf2, a Cap’n’Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene* (1999) (1229)
Autophagy in human health and disease. (2013) (1185)
Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. (1996) (1140)
Mechanisms of cell death in oxidative stress. (2007) (1105)
Carbon Monoxide Generated by Heme Oxygenase 1 Suppresses Endothelial Cell Apoptosis (2000) (999)
Autophagy in human health and disease. (2013) (897)
Heme oxygenase: colors of defense against cellular stress. (2000) (893)
Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia* (1997) (768)
Paneth cells as a site of origin for intestinal inflammation (2013) (578)
Heme oxygenase-1: the "emerging molecule" has arrived. (2002) (541)
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury (2003) (535)
Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. (1999) (525)
Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance (2002) (515)
Fatty Acids Modulate Toll-like Receptor 4 Activation through Regulation of Receptor Dimerization and Recruitment into Lipid Rafts in a Reactive Oxygen Species-dependent Manner* (2009) (492)
Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants1 (2001) (481)
Carbon monoxide provides protection against hyperoxic lung injury. (1999) (434)
Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease (2008) (433)
Inflammasome-regulated cytokines are critical mediators of acute lung injury. (2012) (430)
Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. (2000) (417)
CO as a cellular signaling molecule. (2006) (390)
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis (2006) (376)
Suppression of Inflammatory Cytokine Production by Carbon Monoxide Involves the JNK Pathway and AP-1* (2003) (370)
Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. (1996) (363)
Autophagy proteins regulate innate immune response by inhibiting NALP3 inflammasome-mediated mitochondrial DNA release (2010) (362)
Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts (2006) (356)
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema (2010) (341)
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. (2004) (330)
Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1. (1995) (328)
Hyaluronan Fragments Induce Nitric-oxide Synthase in Murine Macrophages through a Nuclear Factor κB-dependent Mechanism* (1997) (300)
Parallel Induction of Heme Oxygenase-1 and Chemoprotective Phase 2 Enzymes by Electrophiles and Antioxidants: Regulation by Upstream Antioxidant-Responsive Elements (ARE) (1995) (294)
Carbon Monoxide Inhibition of Apoptosis during Ischemia-Reperfusion Lung Injury Is Dependent on the p38 Mitogen-activated Protein Kinase Pathway and Involves Caspase 3* (2003) (277)
Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation. (1995) (271)
Autophagy: A critical regulator of cellular metabolism and homeostasis (2013) (268)
Heme oxygenase-1 inhibits TNF-α-induced apoptosis in cultured fibroblasts (2000) (267)
Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy. (2009) (267)
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. (2013) (265)
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation. (2016) (258)
Autophagy and inflammation in chronic respiratory disease (2018) (255)
Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models. (2005) (226)
Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects. (2003) (222)
Identification of a Second Region Upstream of the Mouse Heme Oxygenase-1 Gene That Functions as a Basal Level and Inducer-dependent Transcription Enhancer (*) (1995) (219)
Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. (1996) (219)
Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death. (2007) (216)
The Impact of Autophagy on Cell Death Modalities (2014) (215)
Carbon Monoxide Protects against Liver Failure through Nitric Oxide–induced Heme Oxygenase 1 (2003) (208)
Autophagic proteins regulate cigarette smoke induced apoptosis: Protective role of heme oxygenase-1 (2008) (208)
Biliverdin administration protects against endotoxin-induced acute lung injury in rats. (2005) (204)
Heme oxygenase-1: from bench to bedside. (2005) (198)
Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. (2003) (196)
Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. (2003) (195)
Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress. (2002) (195)
Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase–Dependent Nitric Oxide Generation (2010) (191)
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. (2011) (181)
MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury. (2003) (181)
Carbon Monoxide Protects against Hyperoxia-induced Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Formation* (2007) (178)
Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide. (1997) (175)
American journal of respiratory cell and molecular biology: Introduction (2003) (175)
Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease. (2007) (173)
Mitochondria in lung disease. (2016) (173)
Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver (2004) (173)
Pathways of cell signaling in hyperoxia. (2003) (172)
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. (2009) (168)
The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-11 (2009) (159)
Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine. (2003) (155)
Carbon monoxide attenuates aeroallergen-induced inflammation in mice. (2001) (153)
Carbon monoxide modulates endotoxin-induced production of granulocyte macrophage colony-stimulating factor in macrophages. (2002) (152)
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. (2009) (150)
Inhaled carbon monoxide confers antiinflammatory effects against ventilator-induced lung injury. (2004) (150)
Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/Bid Pathway* (2003) (149)
Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway. (2006) (149)
Transcriptional activation of the HO-1 gene by lipopolysaccharide is mediated by 5' distal enhancers: role of reactive oxygen intermediates and AP-1. (1998) (140)
Mitochondrial Dysfunction Induces Formation of Lipid Droplets as a Generalized Response to Stress (2013) (138)
Controlled Gene Delivery System Based on Thermosensitive Biodegradable Hydrogel (2003) (136)
Protective effect of carbon monoxide in transplantation (2006) (136)
Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis (2015) (136)
Heme oxygenase-1 and carbon monoxide in pulmonary medicine (2003) (134)
Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway. (2002) (133)
Characterization of macroautophagic flux in vivo using a leupeptin-based assay (2011) (128)
Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts. (2000) (127)
Heat Shock Protein-70 Mediates the Cytoprotective Effect of Carbon Monoxide: Involvement of p38β MAPK and Heat Shock Factor-1 1 (2005) (126)
Carbon Monoxide Inhibits T Lymphocyte Proliferation via Caspase-Dependent Pathway1 (2004) (122)
Inhaled Hydrogen Sulfide Protects against Ventilator-induced Lung Injury (2010) (118)
Carbon Monoxide: To Boldly Go Where NO Has Gone Before (2004) (118)
Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation. (2009) (117)
Stimulation of pro-α1(I) collagen by TGF-β1 in mesangial cells: role of the p38 MAPK pathway (2001) (116)
Caveolin-1: a critical regulator of lung injury. (2011) (113)
Autophagy in lung disease pathogenesis and therapeutics (2015) (112)
Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1. (2008) (109)
AP-1 and STAT mediate hyperoxia-induced gene transcription of heme oxygenase-1. (2000) (109)
Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide. (2005) (108)
Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system. (2007) (108)
Autophagy in the lung. (2010) (108)
Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis (2011) (107)
Oxidant stress responses in influenza virus pneumonia: gene expression and transcription factor activation. (1996) (106)
Mitogen-activated protein kinases regulate HO-1 gene transcription after ischemia-reperfusion lung injury. (2002) (106)
Carbon monoxide suppresses bleomycin-induced lung fibrosis. (2005) (106)
The emerging importance of autophagy in pulmonary diseases. (2012) (104)
Cellular and Humoral Autoreactivity in Idiopathic Pulmonary Fibrosis1 (2007) (104)
CCAAT/enhancer-binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2. (2006) (104)
Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death. (2012) (103)
Carbon monoxide confers protection in sepsis by enhancing beclin 1-dependent autophagy and phagocytosis. (2014) (101)
Carbon monoxide in exhaled breath testing and therapeutics (2013) (100)
Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility (2003) (99)
Depletion of pulmonary EC-SOD after exposure to hyperoxia. (2002) (97)
Gene expression profiling of target genes in ventilator-induced lung injury. (2006) (94)
Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine. (2010) (93)
Mitochondria: commanders of innate immunity and disease? (2012) (93)
TGF-β1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells (2002) (92)
Influenza virus induces expression of antioxidant genes in human epithelial cells. (1994) (90)
Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells. (1999) (89)
Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts. (2003) (88)
Functional Significance of Apoptosis in Chronic Obstructive Pulmonary Disease (2007) (87)
Mitogen-Activated Protein Kinases Regulate Susceptibility to Ventilator-Induced Lung Injury (2008) (86)
Molecular responses to hyperoxia in vivo: relationship to increased tolerance in aged rats. (1995) (83)
Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts. (2008) (83)
Role of oxidants in influenza virus-induced gene expression. (1998) (83)
Emerging role of selective autophagy in human diseases (2014) (82)
Low-dose carbon monoxide inhalation prevents ischemia/reperfusion injury of transplanted rat lung grafts. (2006) (82)
Mechanism of hemoglobin-induced protection against endotoxemia in rats: a ferritin-independent pathway. (1997) (80)
MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production. (2007) (80)
Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease. (2014) (77)
Induction of apoptosis by particulate matter: role of TNF-α and MAPK. (1998) (77)
Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1. (2008) (76)
Carbon monoxide: present and future indications for a medical gas (2013) (76)
Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration. (2006) (75)
Discovery of the gene signature for acute lung injury in patients with sepsis. (2009) (75)
CX3CL1 up-regulation is associated with recruitment of CX3CR1+ mononuclear phagocytes and T lymphocytes in the lungs during cigarette smoke-induced emphysema. (2008) (74)
Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules* (2012) (74)
Influenza virus A infection induces interleukin-8 gene expression in human airway epithelial cells. (1992) (73)
Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus* (2005) (73)
Protective effects of heme oxygenase-1 in acute lung injury. (1999) (72)
Caveolin-1 Inhibits Expression of Antioxidant Enzymes through Direct Interaction with Nuclear Erythroid 2 p45-related Factor-2 (Nrf2)* (2012) (71)
Carbon Monoxide Ameliorates Renal Cold Ischemia-Reperfusion Injury With an Upregulation of Vascular Endothelial Growth Factor by Activation of Hypoxia-Inducible Factor (2008) (71)
Carbon Monoxide Promotes Fas/CD95-induced Apoptosis in Jurkat Cells* (2004) (70)
TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema. (2012) (70)
Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts. (2007) (70)
Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease (2010) (70)
Low-dose carbon monoxide inhalation prevents development of chronic allograft nephropathy. (2006) (69)
Hepatocyte Growth Factor Protects against Hypoxia/Reoxygenation-induced Apoptosis in Endothelial Cells* (2004) (69)
Autophagy in chronic obstructive pulmonary disease: Homeostatic or pathogenic mechanism? (2009) (68)
Heart Allograft Protection with Low-Dose Carbon Monoxide Inhalation: Effects on Inflammatory Mediators and Alloreactive T-cell Responses (2006) (66)
Induction of HSP70 gene expression by the antiproliferative prostaglandin PGA2: a growth-dependent response mediated by activation of heat shock transcription factor (1992) (66)
Carbon monoxide in sepsis. (2007) (66)
The fibrotic phenotype induced by IGFBP-5 is regulated by MAPK activation and egr-1-dependent and -independent mechanisms. (2009) (64)
Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation. (2011) (62)
Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages. (2000) (62)
Low-dose carbon monoxide reduces airway hyperresponsiveness in mice. (2003) (62)
Autophagy: a core cellular process with emerging links to pulmonary disease. (2011) (62)
Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells. (2014) (62)
Mitogen activated protein kinase (MAPK) pathway regulates heme oxygenase-1 gene expression by hypoxia in vascular cells. (2002) (62)
Autophagy in pulmonary diseases. (2012) (59)
Therapeutic applications of carbon monoxide in lung disease. (2006) (58)
Mitochondria: sensors and mediators of innate immune receptor signaling. (2013) (58)
Autophagic flux and oxidative capacity of skeletal muscles during acute starvation (2013) (58)
"Ciliophagy": The consumption of cilia components by autophagy. (2014) (58)
Insulin-like growth factor binding protein 5 induces skin fibrosis: A novel murine model for dermal fibrosis. (2006) (58)
Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells: role of the p38 MAPK pathway. (2001) (57)
Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC2-Deficient Cells to the Antimetabolite 6-Aminonicotinamide (2013) (57)
Carbon monoxide prevents ventilator-induced lung injury via caveolin-1* (2009) (57)
Isolation of mouse respiratory epithelial cells and exposure to experimental cigarette smoke at air liquid interface. (2011) (56)
Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis (2018) (55)
The Influence of Radiographic Phenotype and Smoking Status on Peripheral Blood Biomarker Patterns in Chronic Obstructive Pulmonary Disease (2009) (55)
Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo. (2008) (55)
Regulation of autophagy in oxygen-dependent cellular stress. (2013) (54)
Autophagy: a potential therapeutic target in lung diseases. (2013) (54)
Cytoprotective and anti-inflammatory actions of carbon monoxide in organ injury and sepsis models. (2007) (53)
Autophagy in vascular disease. (2010) (52)
Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells. (1999) (52)
Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38β MAPK and heat shock factor-1 (2006) (50)
Regulation and functional significance of autophagy in respiratory cell biology and disease. (2013) (50)
Carbon monoxide-dependent signaling (2002) (48)
Molecular regulation of autophagy and its implications for metabolic diseases (2014) (47)
Evaluation of inhaled carbon monoxide as an anti-inflammatory therapy in a nonhuman primate model of lung inflammation. (2010) (46)
Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells. (2005) (46)
Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure (2017) (46)
Induction of apoptosis by particulate matter: role of TNF-alpha and MAPK. (1998) (46)
Emerging role of carbon monoxide in physiologic and pathophysiologic states. (2002) (45)
Pulmonary apoptosis in aged and oxygen-tolerant rats exposed to hyperoxia. (1998) (45)
TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells. (2002) (43)
Deacetylation of p53 induces autophagy by suppressing Bmf expression (2013) (43)
Autophagy: An Integral Component of the Mammalian Stress Response. (2013) (42)
Calcium mediates expression of stress‐response genes in prostaglandin A2‐induced growth arrest (1994) (42)
Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis. (2011) (42)
Regulation of IL-1beta -induced GM-CSF production in human airway smooth muscle cells by carbon monoxide. (2003) (41)
Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis. (2012) (41)
Protein Kinase Cα and ζ Differentially Regulate Death-Inducing Signaling Complex Formation in Cigarette Smoke Extract-Induced Apoptosis1 (2008) (40)
Autophagy: cellular defense to excessive inflammation. (2012) (39)
FLIP Protects against Hypoxia/Reoxygenation-Induced Endothelial Cell Apoptosis by Inhibiting Bax Activation (2005) (39)
Cell growth inhibition by prostaglandin A2 results in elevated expression of gadd153 mRNA. (1992) (39)
Identifying targets for COPD treatment through gene expression analyses (2008) (38)
p62 sequestosome 1/light chain 3b complex confers cytoprotection on lung epithelial cells after hyperoxia. (2013) (37)
Heme oxygenase-1 protects the heart. (2001) (36)
Deficiency in the c-Jun NH2-terminal kinase signaling pathway confers susceptibility to hyperoxic lung injury in mice. (2003) (35)
Carbon monoxide inhibits IL-17-induced IL-6 production through the MAPK pathway in human pulmonary epithelial cells. (2005) (35)
Cross talk between autophagy and apoptosis in pulmonary hypertension (2012) (33)
Differential modulation by exogenous carbon monoxide of TNF-alpha stimulated mitogen-activated protein kinases in rat pulmonary artery endothelial cells. (2002) (32)
Dampening insulin signaling by an NLRP3 'meta-flammasome' (2011) (32)
Cytoprotection of heme oxygenase-1/carbon monoxide in lung injury. (2005) (32)
Haem oxygenase-1 overexpression alters intracellular iron distribution. (2013) (30)
Network analysis of temporal effects of intermittent and sustained hypoxia on rat lungs. (2008) (30)
Alpha-2 adrenoceptor blockade protects rats against lipopolysaccharide. (1996) (29)
Autophagic proteins (2012) (28)
Heme Oxygenase-1/CO as protective mediators in cigarette smoke- induced lung cell injury and chronic obstructive pulmonary disease. (2012) (28)
Alterations in the molecular response to DNA damage during cellular aging of cultured fibroblasts: Reduced AP‐1 activation and collagenase gene expression (1995) (28)
Regenerative pulmonary medicine: potential and promise, pitfalls and challenges (2012) (27)
Deadly triplex: Smoke, autophagy and apoptosis (2011) (27)
Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis. (2008) (27)
Urethan anesthesia protects rats against lethal endotoxemia and reduces TNF-α release (1996) (27)
Carbon monoxide modulates alpha-smooth muscle actin and small proline rich-1a expression in fibrosis. (2009) (25)
FLIP inhibits endothelial cell apoptosis during hyperoxia by suppressing Bax. (2007) (24)
The saga of leucine zippers continues: in response to oxidative stress. (2002) (24)
Phosphatidylinositol 3-kinase/Akt pathway mediates heme oxygenase-1 regulation by lipopolysaccharide. (2005) (24)
Transcriptional regulation of the HO-1 gene in cultured macrophages exposed to model airborne particulate matter. (2003) (22)
Exhaled monoxides as a pulmonary function test: use of exhaled nitric oxide and carbon monoxide. (2001) (21)
Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells. (1999) (21)
Heme Oxygenase-1 and Transplantation (2004) (20)
Nucleotide-Binding Oligomerization Domain Protein 2 Deficiency Enhances Neointimal Formation in Response to Vascular Injury (2011) (19)
Carbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cells (2011) (19)
“Ciliophagy” (2014) (18)
Comprehensive analysis of gene expression on GOLD-2 Versus GOLD-0 smokers reveals novel genes important in the pathogenesis of COPD. (2006) (18)
Erratum: Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: Involvement of p38β MAPK and heat shock factor-1 (Journal of Immunology (2005) 175 (2622-2629)) (2006) (17)
Nitric oxide-deficiency regulates hepatic heme oxygenase-1. (2008) (17)
A PEPTIDE WITH ANTI-TRANSGLUTAMINASE ACTIVITY DECREASES LIPOPOLYSACCHARIDE-INDUCED LUNG INFLAMMATION IN MICE (2006) (16)
Alterations in Nitric Oxide and Cytokine Production with Airway Inflammation in the Absence of IL-101 (2005) (16)
Lung redox homeostasis: emerging concepts. (2000) (15)
Gaseous therapeutics in acute lung injury. (2010) (15)
Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans. (2007) (15)
Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells. (1999) (15)
Pulmonary apoptosis in aged and oxygen-tolerant rats exposed to hyperoxia. (1998) (14)
Carbon monoxide-dependent signaling. (2002) (12)
NHLBI Workshop: Respiratory Medicine-Related Research Training for Adult and Pediatric Fellows (2009) (11)
Urethan anesthesia protects rats against lethal endotoxemia and reduces TNF-alpha release. (1996) (11)
Caveolin-1: a critical regulator of pulmonary vascular architecture and nitric oxide bioavailability in pulmonary hypertension. (2008) (10)
Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins. (2014) (9)
Analyzing autophagy in clinical tissues of lung and vascular diseases. (2009) (9)
Enhanced nitric oxide production associated with airway hyporesponsiveness in the absence of IL-10. (2005) (8)
Autophagy Proteins Regulate Innate Immune Response By Inhibiting NALP3 Inflammasome-Mediated Mitochondrial DAN Release (2011) (8)
Epigenetics and the unfolded protein response in the lung: emerging role for microRNAs. (2014) (7)
Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide. (1997) (7)
A new road to induce heme oxygenase-1 expression by carbon monoxide. (2007) (7)
Carbon monoxide provides protection against hyperoxic lung injury. (1999) (5)
Inhaled CO in the treatment of acute lung injury. (2008) (5)
Cell Death and Repair in Lung Disease (2014) (5)
Erratum: Caveolin-1 expression by means of p38β mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide (Proceedings of the National Academy of Sciences of the United States of America (August 9, 2005) 102, 32 (11319-11324)) (2005) (5)
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. (2020) (4)
Exhaled carbon monoxide: mechanisms and clinical applications (2010) (4)
Depletion of Pulmonary EC-SOD Following Exposure to Hyperoxia (2002) (4)
Caveolin-1 stops profibrogenic signaling? (2008) (3)
Synthesis and Metabolism of Carbon Monoxide (2004) (3)
Stimulation of proa 1 ( I ) collagen by TGF-b 1 in mesangial cells : role of the p 38 MAPK pathway (2001) (3)
Application of coherent antistokes Raman scattering (CARS) to imaging mammalian cells: a means for gaining molecular selectivity in multiphoton imaging (2001) (3)
Apoptosis in Lung Injury and Disease (2009) (2)
Caveolin-1 Protects Against Cigarette Smoking Induced Autophagic Cell Death and Emphysema in Chronic Obstructive Pulmonary Disease. (2009) (2)
Egr-1-Dependent Autophagy Inhibits the Development of Pulmonary Arterial Hypertension. (2009) (2)
Testing the rebound peer review concept. (2013) (2)
Stimulation of pro-a1(I) collagen by TGF-b1 in mesangial cells: role of the p38 MAPK pathway (2001) (2)
Protein Kinase C and Differentially Regulate Death-Inducing Signaling Complex Formation in Cigarette Smoke Extract-Induced Apoptosis (2008) (1)
Gene expression profiling in chronic obstructive pulmonary disease. (2008) (1)
CAN INHALATION CARBON MONOXIDE BE UTILIZED AS A THERAPEUTIC MODALITY IN HUMAN DISEASES (2005) (1)
Inducing Hypoxemia in Healthy Humans: A Method for Intermittently Lowering Arterial Blood Oxygenation During Physiological Studies (2008) (1)
The protective role of carbon monoxide in ventilator induced lung injury: BAPC1-3 (2007) (1)
Heme Oxygenase-1 in Acute Lung Injury (2001) (1)
Carbon Monoxide Induces Autophagy In Respiratory Epithelial Cells By Generation Of Mitochondrial Reactive Oxygen Species (2010) (1)
Statins Promote NALP3 Inflammasome Activation Through Increased Mitochondrial ROS Generation In Macrophages (2011) (1)
Early Inhibition of heme oxygenase enzymatic activity precipitates xenograft rejection. (1999) (1)
Peripheral Blood Biomarkers Of Acute Exacerbation In Idiopathic Pulmonary Fibrosis (2010) (1)
Regulation of gene expression in oxidative stress (1993) (1)
State of the Art Heme Oxygenase-1 From Bench to Bedside (2005) (1)
Systemic Biomarker Pattern in Different Chronic Obstructive Pulmonary Disease Phenotypes Independent of Smoking Status (2006) (1)
Heme Oxygenase-1 and Carbon Monoxide in Vascular Regulation (2005) (0)
Identification Of Mouse Lung Transcripts Exhibiting Circadian Variation In Expression (2012) (0)
Increased Autophagy In A Mouse Model Of Ventilator Induced Lung Injury (2010) (0)
Epithelial and Mesenchymal Cell Biology The Fibrotic Phenotype Induced by IGFBP-5 Is Regulated by MAPK Activation and Egr-1-Dependent and-Independent Mechanisms (2010) (0)
Autophagic Protein LC3B Regulates Cigarette Smoke-Induced Extrinsic Apoptosis in Chronic Obstructive Pulmonary Disease (2010) (0)
IL-12p40 Subunit Expression in Lungs of Mice Administered Low-Dose Carbon Monoxide. (2009) (0)
lung epithelial cells mitochondrial production of reactive oxygen species in Lipid-soluble components in cigarette smoke induce (2009) (0)
Alveolar-Specific Gene Expression Profiling in Emphysematous Lungs. (2009) (0)
Ketamine superinduces heme oxygenase-1(HO-1) in murine peritoneal macrophages after exposure to endotoxin (LPS) (1998) (0)
Caveolin-1 Regulates Ciliated Epithelial Cell Stress Responses to Cigarette Smoke. (2009) (0)
32: Low dose carbon monoxide protects rat lung grafts from ischemia-reperfusion (2006) (0)
Gene expression profiling and biomarkers in ARDS (2016) (0)
Involvement Of Ceramides And Dihydroceramides In Lung Apoptosis And Autophagy (2010) (0)
Diurnal Variation In Macroautophagic Activity In Vivo (2011) (0)
The Role Of MTORC1 Activation In Ventilator Induced Lung Injury (2012) (0)
Functional genomics of lung disease: Introduction (2004) (0)
EFFECT OF SLEEP FRAGMENTATION ON LIPID PROFILE IN NORMAL AND OVERWEIGHT SUBJECTS (2007) (0)
Prenatal Tobacco Exposure And Abnormalities In Postnatal Autophagy Effectors (2011) (0)
Endotoxemia Leads To Regulation Of Macroautophagic Activity In Multiple Vital Organs (2010) (0)
Loss Of PTEN-Induced Putative Kinase 1 (PINK1) Exaggerates Cigarette Smoke Induced Cell Death (2012) (0)
BENEFICIAL EFFECT OF CARBON MONOXIDE-INHALATION AGAINST ISCHEMIA/REPERFUSION INJURY AFTER RAT LIVER TRANSPLANTATION: POSSIBLE MECHANISM OF iNOS/NO PATHWAY BLOCKADE (2004) (0)
Cigarette Smoking Induces Cyr61 Expression And Secretion In Pulmonary Epithelial Cells Via Egr-1 Mediated Pathways (2010) (0)
Lung Mononuclear Phagocytes Require Functional CX3CR1 To Express Inflammatory Cytokines During Cigarette Smoke Exposure (2010) (0)
EB2000 symposium report Lung redox homeostasis: emerging concepts (2000) (0)
EFFECT OF SLEEP FRAGMENTATION ON OVERNIGHT OXIDATIVE STRESS, INSULIN, AND GLUCOSE (2006) (0)
TLR4 Deficiency Increases Autophagic Protein LC3B And Promotes Emphysematous Airspace Enlargement In Cigarette Smoke-Exposed Mice (2011) (0)
Correction for Kim et al., Caveolin-1 expression by means of p38β mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide (2021) (0)
Idiopathic Pulmonary Fibrosis Cellular and Humoral Autoreactivity in Zhang (2007) (0)
Chronic alcohol consumption increases heme oxygenase-1 (HO-1) induction following hemorrhagic shock (1996) (0)
Differential gene expression of antioxidant enzymes in macrophages exposed to carbon particles adsorbed with benzo-[a]-pyrene (1997) (0)
Factor-1 MAPK and Heat Shock β Involvement of p 38 Cytoprotective Effect of Carbon Monoxide : Heat Shock Protein-70 Mediates the ChoiIvor (2005) (0)
Genetic susceptibility to hyperoxic lung injury in mice and the role of heme oxygenase (1998) (0)
Endothelial Biomedicine: Heme Oxygenase and Carbon Monoxide in Endothelial Cell Biology (2007) (0)
Correction: Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2). (2020) (0)
Epithelial Functionas a Focus of Ozone-Allergen Interaction (1997) (0)
P62 Regulates Autophagy And Apoptosis Via Interacting Fas Pathways (2011) (0)
PathwayProliferation via Caspase-Dependent Carbon Monoxide Inhibits T Lymphocyte (2003) (0)
THE SYNERGISTIC EFFECT OF CARBON MONOXIDE AND BILIVERDIN FOR KIDNEY AND CARDIAC ISCHEMIA/REPERFUSION INJURY (2004) (0)
O13-02 Carbon monoxide saturates UW solution protects ischemia/reperfusion injury of rat lung grafts (2008) (0)
Carbon Monoxide Negatively Regulates NLRP3 Inflammasome Activation By Inhibiting Mitochondrial ROS Generation In Macrophages (2011) (0)
Absence Of Autophagy Gene LC3B Enhances IL-1b And IL-18 Secretion By Increased Activation Of Caspase-1 (2010) (0)
Caveolin-1 Interacts With The Keap1-Nrf2 System And Regulates The Cellular Antioxidant Capacity In Lung Epithelial Cells (2012) (0)
P62 SQSTM1 Regulates Mitochondria Mediated Apoptosis In Lung Epithelial Cells After Hyperoxia (2012) (0)
QS3. Low Dose Nebulized Nitrite Prevents or Reverses Pulmonary Hypertension and Is Dependent on Xanthine Oxidoreductase (2008) (0)
Carbon Monoxide-induced Autophagy Inhibits The Mortality Of Cecal Ligation And Puncture-induced Sepsis Model (2010) (0)
Regulation of Autophagy by Carbon Monoxide in Vascular and Respiratory Epithelial Cells. (2009) (0)
IREB2 And Smoke Induced Iron Deposition: Novel Biomarkers For COPD Severity And Progression (2012) (0)
Autophagic Responses In Two-Hit Air Pollution/Cigarette Smoke Exposure Models (2012) (0)
OR12,5 IGFBP-5 induces extracellular matrix production via Egr-1 and MAPK-dependent pathways (2008) (0)
biochemistryinjury in primates. I. Physiology and Aerosolized manganese SOD decreases hyperoxic (2015) (0)
ARDS In Patients With Sepsis Is Associated With Differential Expression Of Specific Lipid Signaling Genes (2012) (0)
Role of oxidants in influenza virus-induced gene expression. (1998) (0)
Quantitative CT Square Root Of Wall Area At Pi10 (mm) Correlates With Lung Function And The Development Of Bronchiolitis Obliterans Syndrome Following Allogeneic Hematopoietic Stem Cell Transplantation (2012) (0)
Identification of New Molecular Pathways Involved in the Pathogenesis of Chronic Obstructive Pulmonary Disease by Proteomics Approaches (2012) (0)
The Role Of Autophagy In Cigarette Smoke-Induced Cilia Loss: Implications For Chronic Obstructive Pulmonary Disease (2010) (0)
Abstract 2272: Heme oxygenase-1 regulates apoptosis and autophagy for the survival of renal cancer cells (2012) (0)
Reversal of Lung Emphysema by Endothelial Directed Attenuation of Lrg-1 Signaling (2020) (0)
Global gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. (2005) (0)
Abstract 12644: Aldosterone Activates Autophagy to Increase Vascular Smooth Muscle Cell Collagen Synthesis and Vascular Stiffness (2010) (0)
The Lung Macroautophagy Substrate Proteome: A SYSTEMS BIOLOGY Analysis (2015) (0)
Regulation Of Cellular Autophagy By Heme And Iron (2010) (0)
Impaired Autophagy In Idiopathic Pulmonary Fibrosis (2012) (0)
Activation of extracellular signal-regulated kinase 1 and activator protein-1 by transforming growth factor-beta1 in mesangial cells is dependent on TGF-beta type II receptor (1998) (0)
Carbon Monoxide Inhibits Lung Fibrosis By Inducing Cellular Quiescence Via E2F4 (2012) (0)
Identification Of Novel Molecular Targets By Gene Expression Profiling in Autophagy Protein LC3b Deficient Mice In Hypoxia-induced Pulmonary Hypertension (2010) (0)
Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells (Am J Physiol Lung Cell Mol Physiol, 306, (L1016-L1025), (2014), 10.1152/ajplung.00268.2013) (2018) (0)
Inhaled nitrite treats experimental pulmonary arterial hypertension (2006) (0)
Deletion of Caveolin-1 Protects Hyperoxia Induced Lung Cell Apoptosis Via Up-Regulation of Survivin. (2009) (0)
Cyr61 Regulates Pulmonary Artery Smooth Muscle Cell Proliferation via Akt-survivin Mediated Pathways (2010) (0)
ventilator-induced lung injury Gene expression profiling of target genes in (2015) (0)
Effects of carbon monoxide on airway reactivity and nitric oxide production in the absence of IL-10 (2005) (0)
CCN1 Regulates Pulmonary Hypertension In Murine Models (2012) (0)
STATE OF THE ART Autophagy in Pulmonary Diseases (2016) (0)
Mitogen Activating Protein Kinase (MAPK) mediates carbon particle-induced tumor necrosis factor-α expression (1998) (0)
Cyr61 Is A Novel Regulator In The Pathogenesis Of Cigarette Smoking Induced Emphysema (2012) (0)
The modulatory effects of carbon monoxide on the inflammatory response (2003) (0)
Carbon monoxide potentiates cerulein-induced pancreatitis in chronic alcohol-fed rats (2003) (0)
Cigarette Smoke Induced Autophagy In The Airway Epithelium Promotes Aggrephagy And Ciliaphagy In Models Of Chronic Obstructive Pulmonary Disease (2012) (0)
Therapeutic carbon monoxide may be toxic. Author's reply (2005) (0)
Pre-treatment with low concentrations of carbon monoxide (250 TO 75 ppm) for 3 hr prior to laparotomy protects against postoperative ileus (2003) (0)
Ketamine Increases Expression Of Tumor Necrosis Factor Alpha In Murine Peritoneal Macrophages After Exposure To Endotoxin(LPS) (1998) (0)
LPS Tolerance Regulates Autophagosome and Lysosome-Associated Protein Expression in Mice. (2009) (0)
Endothelial Biomedicine: Function of Hepatocyte Growth Factor and Its Receptor c-Met in Endothelial Cells (2007) (0)
Cell Cycle and Senescence Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC 2-De fi cient Cells to the Antimetabolite 6-Aminonicotinamide (2013) (0)
Extract-Induced Apoptosis Formation in Cigarette Smoke Regulate Death-Inducing Signaling Complex Differentially ζ and α Protein Kinase (2008) (0)
Cigarette Smoke Regulates Cross Talk Between Autophagy And Apoptosis by Induction Of TLR2 And TLR4 Signaling Pathways (2010) (0)
Erratum: Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2) (J. Biol. Chem. (2012) 287 (20922-20930) DOI: 10.1074/jbc.M112.352336) (2020) (0)

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