Austin L. Hughes
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Biology
Austin L. Hughes's Degrees
- PhD Biology University of California, Berkeley
- Masters Biology University of California, Berkeley
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Austin L. Hughes's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection (1988) (1917)
- The evolution of functionally novel proteins after gene duplication (1994) (962)
- Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection. (1989) (907)
- Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia (2000) (767)
- A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks (1995) (638)
- Natural selection at major histocompatibility complex loci of vertebrates. (1998) (610)
- The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes. (2001) (439)
- Reversion of CTL escape–variant immunodeficiency viruses in vivo (2004) (424)
- Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection (2002) (413)
- Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef (1999) (412)
- Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant. (1995) (387)
- A genome-wide screen identifies a single β-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins (2004) (290)
- Positive Darwinian selection promotes charge profile diversity in the antigen-binding cleft of class I major-histocompatibility-complex molecules. (1990) (277)
- Evolution of duplicate genes in a tetraploid animal, Xenopus laevis. (1993) (260)
- New recombinant HLA-B alleles in a tribe of South American Amerindians indicate rapid evolution of MHC class I loci (1992) (258)
- Looking for Darwin in all the wrong places: the misguided quest for positive selection at the nucleotide sequence level (2007) (255)
- Evolution of the major histocompatibility complex: independent origin of nonclassical class I genes in different groups of mammals. (1989) (245)
- Pattern and timing of gene duplication in animal genomes. (2001) (203)
- Natural selection on Plasmodium surface proteins. (1995) (199)
- The MHC class I genes of the rhesus monkey. Different evolutionary histories of MHC class I and II genes in primates. (1996) (195)
- Small genomes for better flyers (1995) (194)
- Major Histocompatibility Complex Class I Alleles Associated with Slow Simian Immunodeficiency Virus Disease Progression Bind Epitopes Recognized by Dominant Acute-Phase Cytotoxic-T-Lymphocyte Responses (2003) (189)
- Adaptive Evolution of Genes and Genomes (2000) (187)
- Gene duplication and the structure of eukaryotic genomes. (2001) (184)
- Phylogenies of Developmentally Important Proteins Do Not Support the Hypothesis of Two Rounds of Genome Duplication Early in Vertebrate History (1999) (182)
- Definition of an epitope and MHC class I molecule recognized by gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys. (1991) (181)
- Evolution of the mammalian MHC: natural selection, recombination, and convergent evolution (1999) (167)
- Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes. (2004) (164)
- Adaptive diversification within a large family of recently duplicated, placentally expressed genes. (2000) (158)
- Positive selection and interallelic recombination at the merozoite surface antigen-1 (MSA-1) locus of Plasmodium falciparum. (1992) (150)
- Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes (1990) (149)
- Natural selection on the gag, pol, and env genes of human immunodeficiency virus 1 (HIV-1). (1995) (136)
- Circumsporozoite protein genes of malaria parasites (Plasmodium spp.): evidence for positive selection on immunogenic regions. (1991) (134)
- The evolutionary biology of poxviruses. (2010) (133)
- MHC Polymorphism and the Design of Captive Breeding Programs (1991) (130)
- Evolution and Human Kinship (1988) (126)
- Comprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques (2007) (126)
- Ancient genome duplications did not structure the human Hox-bearing chromosomes. (2001) (126)
- A novel “chimeric” antibody class in cartilaginous fish: IgM may not be the primordial immunoglobulin (1996) (124)
- Widespread purifying selection at polymorphic sites in human protein-coding loci (2003) (119)
- Phylogenetic tests of the hypothesis of block duplication of homologous genes on human chromosomes 6, 9, and 1. (1998) (115)
- A uniquely high level of recombination at the HLA-B locus. (1994) (115)
- SNPGenie: estimating evolutionary parameters to detect natural selection using pooled next-generation sequencing data (2015) (112)
- Unusually High Frequency MHC Class I Alleles in Mauritian Origin Cynomolgus Macaques (2005) (112)
- Gene duplication and the origin of novel proteins. (2005) (111)
- A Dominant Role for CD8+-T-Lymphocyte Selection in Simian Immunodeficiency Virus Sequence Variation (2004) (110)
- Extraepitopic Compensatory Substitutions Partially Restore Fitness to Simian Immunodeficiency Virus Variants That Escape from an Immunodominant Cytotoxic-T-Lymphocyte Response (2004) (110)
- Evolutionary relationships of class II major-histocompatibility-complex genes in mammals. (1990) (102)
- Escape in One of Two Cytotoxic T-Lymphocyte Epitopes Bound by a High-Frequency Major Histocompatibility Complex Class I Molecule, Mamu-A*02: a Paradigm for Virus Evolution and Persistence? (2002) (102)
- Poxvirus genome evolution by gene gain and loss. (2005) (102)
- Evolution of the Integrin α and β Protein Families (2001) (101)
- Natural selection on the peptide-binding regions of major histocompatibility complex molecules (2004) (99)
- Evolutionary diversification of protein-coding genes of hantaviruses. (2000) (94)
- A Novel Hepacivirus with an Unusually Long and Intrinsically Disordered NS5A Protein in a Wild Old World Primate (2013) (94)
- Adaptive evolution after gene duplication. (2002) (93)
- Mitochondrial genome sequences support ancient population expansion in Plasmodium vivax. (2005) (93)
- Evolution of Divergent Life History Strategies in Marine Alphaproteobacteria (2013) (92)
- The temporal distribution of gene duplication events in a set of highly conserved human gene families. (2003) (92)
- Phylogeny of Trypanosomatidae and Bodonidae (Kinetoplastida) based on 18S rRNA: evidence for paraphyly of Trypanosoma and six other genera. (2003) (91)
- Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain. (1991) (89)
- Ultradeep Pyrosequencing Detects Complex Patterns of CD8+ T-Lymphocyte Escape in Simian Immunodeficiency Virus-Infected Macaques (2009) (86)
- CD8+ T Cells from SIV Elite Controller Macaques Recognize Mamu-B*08-Bound Epitopes and Select for Widespread Viral Variation (2007) (85)
- Very large long–term effective population size in the virulent human malaria parasite Plasmodium falciparum (2001) (85)
- MHC Heterozygote Advantage in Simian Immunodeficiency Virus–Infected Mauritian Cynomolgus Macaques (2010) (85)
- Genomewide Pattern of Synonymous Nucleotide Substitution in Two Complete Genomes of Mycobacterium tuberculosis (2002) (84)
- Evidence for Abundant Slightly Deleterious Polymorphisms in Bacterial Populations (2005) (84)
- Evolutionary instability of the major histocompatibility complex class I loci in New World primates. (1997) (82)
- Coordinated Amino Acid Changes in the Evolution of Mammalian Defensins (1997) (82)
- Rapid evolution of immunoglobulin superfamily C2 domains expressed in immune system cells. (1997) (82)
- Cytotoxic T lymphocytes do not appear to select for mutations in an immunodominant epitope of simian immunodeficiency virus gag. (1992) (81)
- Identification of MHC class I sequences in Chinese-origin rhesus macaques (2007) (80)
- Genome-wide survey for genes horizontally transferred from cellular organisms to baculoviruses. (2003) (80)
- Evidence that intragenic recombination contributes to allelic diversity of the S-RNase gene at the self-incompatibility (S) locus in Petunia inflata. (2001) (79)
- Within-host nucleotide diversity of virus populations: insights from next-generation sequencing. (2015) (78)
- Natural selection and the diversification of vertebrate immune effectors (2002) (77)
- Male size, mating success, and mating strategy in the mosquitofish Gambusia affinis (Poeciliidae) (1985) (76)
- Selection on hemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses (2013) (75)
- Chimpanzee MHC class I A locus alleles are related to only one of the six families of human A locus alleles. (1995) (75)
- 2R or not 2R: Testing hypotheses of genome duplication in early vertebrates (2004) (74)
- Origin and evolution of HLA class I pseudogenes. (1995) (72)
- Whole-Genome Characterization of Human and Simian Immunodeficiency Virus Intrahost Diversity by Ultradeep Pyrosequencing (2010) (72)
- Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2 (2004) (70)
- Complete Characterization of Killer Ig-Like Receptor (KIR) Haplotypes in Mauritian Cynomolgus Macaques: Novel Insights into Nonhuman Primate KIR Gene Content and Organization1 (2008) (70)
- Protein phylogenies provide evidence of a radical discontinuity between arthropod and vertebrate immune systems (1998) (70)
- Origin and Evolution of Viral Interleukin-10 and Other DNA Virus Genes with Vertebrate Homologues (2002) (69)
- Mamu-I: A Novel Primate MHC Class I B-Related Locus with Unusually Low Variability1 (2000) (69)
- Loss of ancestral genes in the genomic evolution of Ciona intestinalis (2005) (68)
- Functional diversification of the toll-like receptor gene family (2008) (68)
- Contrasting roles of interallelic recombination at the HLA-A and HLA-B loci. (1993) (68)
- Natural selection and the evolutionary history of major histocompatibility complex loci. (1998) (67)
- Selection‐driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection (2010) (67)
- Natural selection at the class II major histocompatibility complex loci of mammals. (1994) (66)
- Simultaneous Positive and Purifying Selection on Overlapping Reading Frames of the tat andvpr Genes of Simian Immunodeficiency Virus (2001) (65)
- Models of host-parasite interaction and MHC polymorphism. (1992) (63)
- Genome-Wide Patterns of Nucleotide Substitution Reveal Stringent Functional Constraints on the Protein Sequences of Thermophiles (2004) (63)
- More effective purifying selection on RNA viruses than in DNA viruses. (2007) (63)
- Molecular evolution of the vertebrate immune system (1997) (62)
- Molecular evolution of the NF-κB signaling system (2002) (62)
- The Evolution of Amino Acid Repeat Arrays in Plasmodium and Other Organisms (2004) (61)
- Locus-specific conservation of the HLA class I introns by intra-locus homogenization (1997) (61)
- Maintenance of MHC polymorphism (1992) (61)
- Molecular cloning of orangutan and gibbon MHC class I cDNA. The HLA-A and -B loci diverged over 30 million years ago. (1992) (59)
- Towards a new conceptual approach to "parasitoproteomics". (2005) (58)
- Comprehensive Immunological Evaluation Reveals Surprisingly Few Differences between Elite Controller and Progressor Mamu-B*17-Positive Simian Immunodeficiency Virus-Infected Rhesus Macaques (2008) (58)
- Evolution of adaptive phenotypic traits without positive Darwinian selection (2011) (58)
- Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus (2016) (57)
- Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesterone (2014) (57)
- Evolutionary origin and diversification of the mammalian CD1 antigen genes. (1991) (57)
- Analysis of Hepatitis C Virus Intrahost Diversity across the Coding Region by Ultradeep Pyrosequencing (2012) (55)
- Evolution of the arthropod prophenoloxidase/hexamerin protein family (1999) (54)
- Patterns of nucleotide difference in overlapping and non-overlapping reading frames of papillomavirus genomes. (2005) (54)
- Sequence convergence in the peptide-binding region of primate and rodent MHC class Ib molecules. (1997) (54)
- Evolutionary analysis of a streamlined lineage of surface ocean Roseobacters (2014) (54)
- Aspartic proteinase phylogeny and the origin of pregnancy-associated glycoproteins. (2003) (54)
- Natural selection at the class II major histocompatibility complex loci of mammals (1994) (54)
- Novel Member of the CD209 (DC-SIGN) Gene Family in Primates (2003) (54)
- The evolution of the type I interferon gene family in mammals (1995) (53)
- Near Neutrality (2008) (53)
- DNA repeat arrays in chicken and human genomes and the adaptive evolution of avian genome size (2005) (51)
- High level of functional polymorphism indicates a unique role of natural selection at human immune system loci (2005) (51)
- A new taxonomy of mammalian MHC class I molecules. (1999) (51)
- Genome sequences reveal divergence times of malaria parasite lineages (2010) (50)
- Understanding cytotoxic T‐lymphocyte escape during simian immunodeficiency virus infection (2001) (50)
- MHC class I characterization of Indonesian cynomolgus macaques (2008) (50)
- Evolutionary diversification of the mammalian defensins (1999) (50)
- The MHC E locus in macaques is polymorphic and is conserved between macaques and humans (2004) (49)
- Evidence for ancient balanced polymorphism at the Apical Membrane Antigen-1 (AMA-1) locus of Plasmodium falciparum. (2000) (49)
- AIDS virus–specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape (2007) (49)
- Evolution of the βGRP/GNBP/β-1,3-glucanase family of insects (2012) (49)
- Allelic variation in the circumsporozoite protein of Plasmodium falciparum from Thai field isolates. (1994) (48)
- Evolution of the proteasome components (1997) (48)
- The origin of adaptive phenotypes (2008) (48)
- Codon-based tests of positive selection, branch lengths, and the evolution of mammalian immune system genes (2008) (47)
- Evolution of the ATP-binding-cassette transmembrane transporters of vertebrates. (1994) (46)
- Genome size reduction in the chicken has involved massive loss of ancestral protein-coding genes. (2008) (46)
- Evolution of inhibitors of apoptosis in baculoviruses and their insect hosts. (2002) (46)
- Seasonal changes in fecundity and size at first reproduction in an Indiana Population of the mosquitofish Gambusia affinis (1985) (45)
- Synonymous and nonsynonymous polymorphisms versus divergences in bacterial genomes. (2008) (45)
- Chemokine PARC Gene (SCYA18) Generated by Fusion of Two MIP-1α/LD78α-like Genes (1999) (45)
- Synonymous and Nonsynonymous Substitution Distances Are Correlated in Mouse and Rat Genes (1998) (45)
- Ecology of malaria parasites infecting Southeast Asian macaques: evidence from cytochrome b sequences (2010) (45)
- Evolution of the integrin alpha and beta protein families. (2001) (44)
- Parallel evolution by gene duplication in the genomes of two unicellular fungi. (2003) (44)
- Characterization of 47 MHC class I sequences in Filipino cynomolgus macaques (2009) (43)
- Molecular cloning of cDNA that encode MHC class I molecules from a New World primate (Saguinus oedipus). Natural selection acts at positions that may affect peptide presentation to T cells. (1990) (41)
- Evolutionary relationships of the classes of major histocompatibility complex genes (2004) (41)
- Class I molecules with similar peptide-binding specificities are the result of both common ancestry and convergent evolution (2003) (41)
- Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first. (1994) (41)
- Genome reduction by deletion of paralogs in the marine cyanobacterium Prochlorococcus. (2011) (41)
- Differential loss of ancestral gene families as a source of genomic divergence in animals (2004) (39)
- Phylogeny of the Picornaviridae and differential evolutionary divergence of picornavirus proteins. (2004) (39)
- Coevolution of the vertebrate integrin alpha- and beta-chain genes. (1992) (38)
- High Genetic Diversity and Adaptive Potential of Two Simian Hemorrhagic Fever Viruses in a Wild Primate Population (2014) (38)
- Evolution of introns and exons of class II major histocompatibility complex genes of vertebrates (2000) (38)
- Coding sequence polymorphism in avian mitochondrial genomes reflects population histories (2007) (37)
- Homologous recombination and the pattern of nucleotide substitution in Ehrlichia ruminantium. (2007) (37)
- Peptide binding function and the paradox of HLA disease associations (1996) (37)
- Gene Duplication and the Properties of Biological Networks (2005) (37)
- Molecular phylogenetics of Trypanosomatidae: contrasting results from 18S rRNA and protein phylogenies (2003) (37)
- Escape from CD8+ T Cell Responses in Mamu-B*00801+ Macaques Differentiates Progressors from Elite Controllers (2012) (36)
- Unusually limited nucleotide sequence variation of the expressed major histocompatibility complex class I genes of a New World primate species (Saguinus oedipus) (1991) (35)
- Preferential first-cousin marriage and inclusive fitness (1980) (35)
- Evolution without selection: Form and function by autoevolution (1990) (35)
- Conditional CD8+ T Cell Escape during Acute Simian Immunodeficiency Virus Infection (2011) (35)
- Extensive polymorphism and ancient origin of Plasmodium falciparum. (2002) (34)
- Independent Origin of IFN- and IFN- in Birds and Mammals (2000) (34)
- Biased amino acid composition in repeat regions of Plasmodium antigens. (1999) (34)
- A gene family of putative immune recognition molecules in the hydroid Hydractinia (2007) (34)
- Selection Maintains Low Genomic GC Content in Marine SAR11 Lineages. (2015) (34)
- Male size, mating success, and breeding habitat partitioning in the whitespotted sawyer Monochamus scutellatus (Say) (Coleoptera: Cerambycidae) (1982) (34)
- Coevolution of the mammalian chemokines and their receptors (1999) (34)
- Cross-clade simultaneous HIV drug resistance genotyping for reverse transcriptase, protease, and integrase inhibitor mutations by Illumina MiSeq (2014) (33)
- Cloning of rhesus monkey killer-cell Ig-like receptors (KIRs) from early pregnancy decidua. (2001) (33)
- Differential male mating success in the white spotted sawyer Monochamus scutellatus (Coleoptera: Cerambycidae). (1981) (33)
- Ancient polymorphism and the hypothesis of a recent bottleneck in the malaria parasite Plasmodium falciparum. (1998) (32)
- Genetic Diversity of Near Genome-Wide Hepatitis C Virus Sequences during Chronic Infection: Evidence for Protein Structural Conservation Over Time (2011) (32)
- Reduced variance of gene expression at numerous loci in a population of chickens selected for high feather pecking. (2010) (32)
- Origin and diversification of the L-amino oxidase family in innate immune defenses of animals (2010) (31)
- Bottleneck effects on vaccine-candidate antigen diversity of malaria parasites in Thailand. (2010) (31)
- Reproductive behaviour and sexual dimorphism in the white-spotted sawyer Monochamus scutellatus (Say). (1979) (31)
- Nucleotide Substitution and Recombination at Orthologous Loci in Staphylococcus aureus (2005) (31)
- Evolutionary relationships of vertebrate NACHT domain-containing proteins (2006) (31)
- Non-random association of transposable elements with duplicated genomic blocks in Arabidopsis thaliana. (2003) (30)
- Gene family content-based phylogeny of prokaryotes: the effect of criteria for inferring homology. (2005) (30)
- Effects of Natural Selection on Interpopulation Divergence at Polymorphic Sites in Human Protein-Coding Loci (2005) (30)
- Nucleotide sequence polymorphism at the apical membrane antigen-1 locus reveals population history of Plasmodium vivax in Thailand. (2009) (30)
- Evolution of a new nonclassical MHC class I locus in two Old World primate species (1999) (30)
- MHC class I-processed pseudogenes in New World primates provide evidence for rapid turnover of MHC class I genes. (1996) (30)
- Expression Patterns of Duplicate Genes in the Developing Root in Arabidopsis thaliana (2005) (30)
- Adaptive evolution in the rat olfactory receptor gene family (1993) (30)
- Transmission of Clonal Hepatitis C Virus Genomes Reveals the Dominant but Transitory Role of CD8+ T Cells in Early Viral Evolution (2011) (30)
- Conservation of cytotoxic T lymphocyte (CTL) epitopes as a host strategy to constrain parasite adaptation: evidence from the nef gene of human immunodeficiency virus 1 (HIV-1). (1998) (29)
- Sequence and diversity of rhesus monkey T-cell receptor β chain genes (2004) (29)
- Contrasting evolutionary rates in the duplicate chaperonin genes of Mycobacterium tuberculosis and M. leprae. (1993) (29)
- Birth-and-death evolution of protein-coding regions and concerted evolution of non-coding regions in the multi-component genomes of nanoviruses. (2004) (28)
- Nucleotide sequence polymorphism in circoviruses. (2008) (28)
- Asymmetric contests among sawyer beetles (Cerambycidae: Monochamus notatus and Monochamus scutellatus) (1987) (27)
- Natural selection of K13 mutants of Plasmodium falciparum in response to artemisinin combination therapies in Thailand. (2016) (27)
- Small effective population sizes and rare nonsynonymous variants in potyviruses. (2009) (27)
- Differential human impact on the survival of genetically distinct avian lineages (1999) (27)
- Sequence and diversity of rhesus monkey T-cell receptor beta chain genes. (1992) (27)
- Shedding Genomic Ballast: Extensive Parallel Loss of Ancestral Gene Families in Animals (2004) (26)
- Ancient common ancestry of the merozoite surface protein 1 of Plasmodium vivax as inferred from its homologue in Plasmodium knowlesi. (2006) (26)
- Ancient interlocus exon exchange in the history of the HLA-A locus. (1989) (26)
- Self peptides bound by HLA class I molecules are derived from highly conserved regions of a set of evolutionarily conserved proteins (2004) (26)
- Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus. (2002) (26)
- Immunodominance of a single CTL epitope in a primate species with limited MHC class I polymorphism. (1997) (25)
- Comparative evolutionary rates of introns and exons in murine rodents (1997) (25)
- Nonlinear relationships among evolutionary rates identify regions of functional divergence in heat-shock protein 70 genes. (1993) (25)
- Evolution of the lung surfactant proteins in birds and mammals (2007) (25)
- Paternal investment and sexual size dimorphism in North American passerines (1986) (25)
- Polymorphism at the apical membrane antigen 1 locus reflects the world population history of Plasmodium vivax (2008) (25)
- Malaria parasite sequences from chimpanzee support the co-speciation hypothesis for the origin of virulent human malaria (Plasmodium falciparum). (2010) (25)
- Genome-wide SNP typing reveals signatures of population history. (2008) (24)
- Molecular evolution of the NF-kappaB signaling system. (2002) (24)
- Evolution of Suiform Aromatases: Ancestral Duplication with Conservation of Tissue-Specific Expression in the Collared Peccary (Pecari tayassu) (2007) (24)
- Molecular evolution of viral fusion and matrix protein genes and phylogenetic relationships among the Paramyxoviridae. (2001) (24)
- Phylogenetic analysis of genome rearrangements among five mammalian orders. (2012) (24)
- Variation in the pattern of synonymous and nonsynonymous difference between two fungal genomes. (2005) (23)
- Pattern of gene duplication in the Cotesia congregata Bracovirus. (2006) (23)
- The Future of Data Analysis in Evolutionary Genomics (2006) (23)
- Comparing effective population sizes of dominant marine alphaproteobacteria lineages. (2014) (23)
- Recombinational histories of avian infectious bronchitis virus and turkey coronavirus (2011) (23)
- Chemokine PARC gene (SCYA18) generated by fusion of two MIP-1alpha/LD78alpha-like genes. (1999) (23)
- Evolution of cysteine proteinases in eukaryotes. (1994) (23)
- Arteriviruses, Pegiviruses, and Lentiviruses Are Common among Wild African Monkeys (2016) (22)
- More radical amino acid replacements in primates than in rodents: support for the evolutionary role of effective population size. (2009) (22)
- Maintenance of DQB1 polymorphisms in primates. (1992) (22)
- Genetically distinct cell populations in naturally occurring bone marrow-chimeric primates express similar MHC class I gene products. (1990) (22)
- Modes of evolution in the protease and kringle domains of the plasminogen-prothrombin family. (2000) (22)
- Codon volatility as an indicator of positive selection: data from eukaryotic genome comparisons. (2005) (21)
- Molecular analysis of HLA-B35 alleles and their relationship to HLA-B15 alleles. (1997) (21)
- Characterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques (2011) (21)
- Low Level of Sequence Diversity at Merozoite Surface Protein-1 Locus of Plasmodium ovale curtisi and P. ovale wallikeri from Thai Isolates (2013) (21)
- Two patterns of genome organization in mammals: the chromosomal distribution of duplicate genes in human and mouse. (2004) (21)
- Genomics and Diversity of the Common Marmoset Monkey NK Complex12 (2007) (21)
- Likelihood-ratio tests for positive selection of human and mouse duplicate genes reveal nonconservative and anomalous properties of widely used methods. (2007) (21)
- Patterns of sequence evolution at epitopes for host antibodies and cytotoxic T-lymphocytes in human immunodeficiency virus type 1. (2006) (19)
- Adaptive evolution of mammalian aromatases: lessons from Suiformes. (2007) (19)
- Experimental Analysis of Sources of Error in Evolutionary Studies Based on Roche/454 Pyrosequencing of Viral Genomes (2012) (19)
- Between-Host Evolution of Cytotoxic T-Lymphocyte Epitopes in Human Immunodeficiency Virus Type 1: an Approach Based on Phylogenetically Independent Comparisons (2004) (19)
- Endemic Bird Areas of the World: Priorities for Biodiversity Conservation. Alison J. Stattersfield , Michael J. Crosby , Adrian J. Long , David C. Wege (2000) (19)
- Natural selection on apical membrane antigen-1 of Plasmodium falciparum. (1999) (18)
- The extent of nucleotide polymorphism is highly variable across a 3-kb region on Plasmodium falciparum chromosome 2. (2002) (18)
- Growth of adult mosquitofish Gambusia affinis in the laboratory (1986) (18)
- Female choice of mates in a polygynous insect, the whitespotted sawyer Monochamus scutellatus (1985) (18)
- Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H 5 N 1 influenza viruses (2013) (18)
- Gene duplication and recombination in the evolution of mammalian Fc receptors (1996) (18)
- Evolution of the salivary apyrases of blood-feeding arthropods. (2013) (18)
- Evolution of cytotoxic T-lymphocyte epitopes in hepatitis B virus. (2007) (17)
- Seasonal trends in body size of adult male mosquitofish,Gambusia affinis, with evidence for their social control (1985) (17)
- Evidence for at least three transcribed BoLA class I loci (2004) (17)
- Alternative splicing, gene duplication and connectivity in the genetic interaction network of the nematode worm Caenorhabditis elegans (2008) (17)
- Evolutionary diversification of the avian fatty acid-binding proteins. (2011) (17)
- Evolutionary change of predicted cytotoxic T cell epitopes of dengue virus. (2001) (17)
- Patterns of Sequence Divergence in 5′ Intergenic Spacers and Linked Coding Regions in 10 Species of Pathogenic Bacteria Reveal Distinct Recombinational Histories (2004) (17)
- Micro-scale signature of purifying selection in Marburg virus genomes. (2007) (17)
- Evolution of the human killer cell inhibitory receptor family. (2002) (17)
- Placental expression and molecular characterization of aromatase cytochrome P450 in the spotted hyena (Crocuta crocuta). (2007) (16)
- Evolutionary diversification of aminopeptidase N in Lepidoptera by conserved clade-specific amino acid residues. (2014) (16)
- Segmental exchange between MHC class I genes in a higher primate: recombination in the gorilla between the ancestor of a human non-functional gene and an A locus gene (1991) (16)
- Rates of amino acid evolution in the 26- and 28-kDa glutathione S-transferases of Schistosoma. (1993) (16)
- Within-host evolution of CD8+-TL epitopes encoded by overlapping and non-overlapping reading frames of simian immunodeficiency virus (2005) (16)
- Stimuli eliciting foodcalling in domestic chickens (1982) (16)
- HLA-A*8001 is a member of a newly discovered ancient family of HLA-A alleles. (1993) (16)
- Concerted evolution of exons and introns in the MHC-linked tenascin-X gene of mammals. (1999) (15)
- Independent gene duplications, not concerted evolution, explain relationships among class I MHC genes of murine rodents (2004) (15)
- Characterization of cynomolgus and vervet monkey placental MHC class I expression: diversity of the nonhuman primate AG locus (2009) (15)
- Natural selection maintains a stable polymorphism at the circumsporozoite protein locus of Plasmodium falciparum in a low endemic area. (2009) (15)
- Rapid Evolution of the Trophoblast Kunitz Domain Proteins (TKDPs)—A Multigene Family in Ruminant Ungulates (2006) (15)
- Environmental kinetoplastid-like 18S rRNA sequences and phylogenetic relationships among Trypanosomatidae: paraphyly of the genus Trypanosoma. (2005) (14)
- Recent Mammalian Gene Duplications: Robust Search for Functionally Divergent Gene Pairs (2004) (14)
- La reconstruction phylogénétique. Concepts et méthodes, Pierre Darlu and Pascal Tassy. Masson, Paris. xv + 245 pp. Paperback, 190 Francs (in French). (1994) (14)
- Evolution of Vertebrate Voltage-Gated Ion Channel α Chains by Sequential Gene Duplication (2003) (14)
- Phylogenetic analysis supports horizontal gene transfer of L-amino acid oxidase gene in Streptococcus oligofermentans. (2012) (14)
- Consistent across-tissue signatures of differential gene expression in Crohn's disease (2005) (14)
- Characterization and Phylogenetic Relationship of Prosimian MHC Class I Genes (2002) (14)
- The T-cell receptor β chain-encoding gene repertoire of a New World primate species, the cotton-top tamarin (1996) (14)
- Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function. (2017) (14)
- Accumulation of slightly deleterious mutations in the mitochondrial genome: a hallmark of animal domestication. (2013) (13)
- Reduced microsatellite heterozygosity in island endemics supports the role of long-term effective population size in avian microsatellite diversity (2010) (13)
- Perinatal Transmission and Viral Evolution of Hepatitis C Virus Quasispecies in Infants Coinfected With HIV (2004) (13)
- SIV Genome-Wide Pyrosequencing Provides a Comprehensive and Unbiased View of Variation within and outside CD8 T Lymphocyte Epitopes (2012) (13)
- Transposable Element Distribution in the Yeast Genome Reflects A Role in Repeated Genomic Rearrangement Events on an Evolutionary Time Scale (2004) (13)
- Phylogeny and recombination history of gallid herpesvirus 2 (Marek's disease virus) genomes. (2007) (13)
- Runaway evolution of the male-specific exon of the doublesex gene in Diptera. (2011) (12)
- Attraction of adult tribolium confusum to flour conditioned by male conspecifics (1982) (12)
- Confidence of paternity and wife-sharing in polygynous and polyandrous systems (1982) (12)
- Differential selective pressures on the merozoite surface protein 2 locus of Plasmodium falciparum in a low endemic area. (2008) (12)
- Cloning of rhesus monkey LILRs. (2006) (11)
- Kin Selection of Complex Behavioral Strategies (1983) (11)
- Distinctive pattern of sequence polymorphism in the NS3 protein of hepatitis C virus type 1b reflects conflicting evolutionary pressures. (2008) (11)
- Relaxation of purifying selection on live attenuated vaccine strains of the family Paramyxoviridae. (2009) (11)
- Pattern of divergence of amino acid sequences encoded by paralogous genes in human and pufferfish. (2004) (11)
- Sequence and evolution of cattle MHC class I cDNAs: concerted evolution has not taken place in cattle (2004) (11)
- Origin of ecdysosteroid UDP-glycosyltransferases of baculoviruses through horizontal gene transfer from Lepidoptera (2013) (11)
- Evolution of the src-related protein tyrosine kinases. (1996) (11)
- Class I and class II MHC bind self peptide sets that are strikingly different in their evolutionary characteristics (2000) (11)
- Variable intensity of purifying selection on cytotoxic T-lymphocyte epitopes in hepatitis C virus. (2007) (11)
- Evolution of vertebrate voltage-gated ion channel alpha chains by sequential gene duplication. (2003) (10)
- Ongoing purifying selection on intergenic spacers in group A streptococcus. (2011) (10)
- Behavioral correlates of post-breeding weight change in a captive flock of American flamingos (Phoenicopterus ruber ruber). (2013) (10)
- Evolutionary diversification of the vertebrate transferrin multi-gene family (2014) (10)
- Dynamics of haplotype frequency change in a CD8+TL epitope of simian immunodeficiency virus. (2010) (10)
- Kin networks and political leadership in a stateless society, the Toda of South India (1988) (10)
- Avian species described on the basis of DNA only. (1992) (10)
- Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae (2007) (9)
- Evolutionary conservation of amino acid composition in paralogous insect vitellogenins. (2010) (9)
- Rapid fixation of a distinctive sequence motif in the 3' noncoding region of the clade of West Nile virus invading North America. (2007) (9)
- Independent origin of IFN-alpha and IFN-beta in birds and mammals. (2000) (9)
- Evolution of the interleukin-1 gene family in mammals (1994) (9)
- Interallelic recombination has not played a major role in the history of the HLA-C locus (1996) (9)
- Testing for interlocus genetic exchange in the MHC: a reply to Andersson and co-workers (2004) (8)
- The evolutionary biology of viruses, Stephen S. Morse, ed., New York: Raven Press, 1993, xi + 353 pages, $69.00 (1994) (8)
- dN/dS does not show positive selection drives separation of polar-tropical SAR11 populations (2012) (8)
- Sexual Selection and Mate Choice: Insights from Neutralist Perspectives (2015) (8)
- PolyAna: analyzing synonymous and nonsynonymous polymorphic sites (2011) (8)
- A STATISTICAL ANALYSIS OF FACTORS ASSOCIATED WITH HISTORICAL EXTINCTION AND CURRENT ENDANGERMENT OF NON-PASSERINE BIRDS (2004) (8)
- HLA-DRA promoter polymorphism and diversity generation within the immune system (1997) (8)
- Evolution of thesrc-related protein tyrosine kinases (1996) (8)
- Molecular phylogenetic evidence of cytotoxic T lymphocyte (CTL) selection on human immunodeficiency virus type 1 (HIV-1) (1999) (8)
- Stability of social behavior in captive American Flamingos (Phoenicopterus ruber): A quantitative case study. (2015) (8)
- Life-history evolution at the molecular level: adaptive amino acid composition of avian vitellogenins (2015) (8)
- Being in the thick of things: context-dependent network centrality in a captive flock of American flamingos (2014) (8)
- Conditional Immune Escape during Chronic Simian Immunodeficiency Virus Infection (2015) (8)
- Seasonal changes in sexual receptivity of female mosquitofish Gambusia affinis (1986) (8)
- Nucleotide usage, synonymous substitution pattern, and past recombination in genomes of Streptococcus pyogenes. (2007) (8)
- Acute Phase CD8+ T Lymphocytes against Alternate Reading Frame Epitopes Select for Rapid Viral Escape during SIV Infection (2013) (8)
- Conflicting selection pressures target the NS3 protein in hepatitis C virus genotypes 1a and 1b. (2010) (7)
- Testing for Behavioral Lateralization in Observational Data: a Monte Carlo Approach Applied to Neck-looping in American Flamingos (2014) (7)
- Evolution of bill size in relation to body size in toucans and hornbills (Aves: Piciformes and Bucerotiformes) (2014) (7)
- Nucleotide substitution at the highly polymorphic K1 locus of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus). (2007) (7)
- Some methods for analyzing the structure and behavior of human kin groups (1984) (7)
- Conserved proteins as immunogens: glutathione S-transferase of Schistosoma. (1994) (7)
- A phylogenetic approach to gene expression data: evidence for the evolutionary origin of mammalian leukocyte phenotypes (2009) (7)
- Evolution of New World Primate MHC Class I Genes (1991) (7)
- Kin coalitions and social dominance (1986) (7)
- A dimorphic Alu Sb-like insertion in COL3A1 is ethnic-specific (1996) (7)
- Synonymous and Nonsynonymous Polymorphism vs . Divergence in Bacterial Genomes (2008) (7)
- Evolution of the Heme Peroxidases of Culicidae (Diptera) (2012) (7)
- Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus (2010) (6)
- Genomic catastrophism and the origin of vertebrate immunity. (1999) (6)
- Across-tissue expression and evolution of genes controlled by the Aire transcription factor. (2006) (6)
- The effect of branch lengths on phylogeny: an empirical study using highly conserved orthologs from mammalian genomes. (2007) (6)
- Cw*1701, a new HLA-C allelic lineage with an unusual transmembrane domain. (1997) (6)
- Evolution of the Host Defense System (2002) (6)
- Two more chimpanzee Patr-A locus alleles related to the HLA-A1/A2/A11 family (1993) (6)
- Syrian hamsters express diverse MHC class I gene products. (1990) (5)
- Gene duplication and MHC origins (2000) (5)
- Birth-and-Death Evolution (2004) (5)
- Frequency and intensity of chick distress calls: Effects on maternal foodcalling in chickens (1982) (5)
- Independent Origin of IFN- a and IFN-b in Birds and Mammals (2000) (5)
- Coevolution of the Vertebrate Integrin aand p-Chain Genes (1998) (5)
- Vertebrate Immune System: Evolution (2006) (5)
- The quagga case: Molecular evolution of an extinct species (1988) (5)
- Amino acid sequence constraint and gene expression pattern across the life history in the malaria parasite Plasmodium falciparum. (2005) (5)
- Social and Antisocial Behavior (1987) (5)
- Temporal pattern of vocalization type usage in singing sessions of male tyrant flycatchers (Tyranninae) (2008) (4)
- Distinctive amino acid composition profiles in salivary proteins of the tick Ixodes scapularis. (2011) (4)
- Female Reproductive Effort and Sexual Selection on Males of Waterfowl (2013) (4)
- Indices of Anseriform body shape based on the relative size of major skeletal elements and their relationship to reproductive effort (2013) (4)
- Biological relatedness and social structure (1986) (4)
- Adaptive amino acid composition in collagens of parasitic nematodes. (2015) (4)
- Polyploidization and Vertebrate Origins: A Review of the Evidence (2000) (4)
- The pattern of nucleotide difference at individual codons among mouse, rat, and human. (2005) (4)
- Evolution in the Post-Genome Era (2009) (4)
- The Need for Megatechnologies: Massive Sequencing, Proteomics and Bioinformatics (2007) (3)
- Genetic markers: Strength in numbers (2002) (3)
- Female infanticide: Sex ratio manipulation in humans☆ (1981) (3)
- Evolutionary Diversification of Insect Innexins (2014) (3)
- Conflicting selection pressures on T-cell epitopes in HIV-1 subtype B. (2011) (3)
- Major Histocompatibility Complex (MHC) Genes: Evolution (2008) (3)
- Monte carlo simulation of HIV-1 evolution in response to selection by antibodies (2002) (3)
- Relaxation of purifying selection on the SAD lineage of live attenuated oral vaccines for rabies virus. (2009) (3)
- Amino acid sequence coevolution in the insect bursicon ligand-receptor system. (2012) (2)
- Genomes of mice and men. (2003) (2)
- Two Models of Evolution of the Class I MHC (1991) (2)
- DNA from a 7000-year-old brain (1988) (2)
- Picking winners in animal contests (1986) (2)
- Conditional CD 8 T Cell Escape during Acute Simian Immunodeficiency Virus Infection (2011) (2)
- A survey of schistosome protein domain types: insights into unique biological properties. (2011) (2)
- Evolutionary origin of the Jiv90 gene of Pestivirus. (2004) (2)
- Myths and Realities of Gene Duplication (2011) (2)
- Stereotyped and non-stereotyped features of the temporal patterning of singing sessions in the ovenbird Seiurus auricapillus (2011) (2)
- Evidence of positive selection at the Lyb-2 locus of the mouse (2004) (2)
- Positive selection in a multi~gene family: Catfish olfactory receptors. (1993) (2)
- P20-16. Ultra-deep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in SIV-infected macaques (2009) (2)
- Multiple Forms of Aromatase in Suiformes: Tissue Distribution, Regulation, and Functional Significance (2013) (2)
- Involucrin genes of primates: Rapid evolution of a repeating DNA segment (1990) (2)
- O689 - Trans-species polymorphism vs. Independent evolution of class II MHC sequence motifs (1996) (1)
- Natural Selection and the Genome (2011) (1)
- Chaos Game Representation: An Alignment-Free Technique for Exploring Evolutionary Relationships of Protein Sequences (2018) (1)
- Correction: High Genetic Diversity and Adaptive Potential of Two Simian Hemorrhagic Fever Viruses in a Wild Primate Population (2013) (1)
- Natural Selection and Sequence Polymorphism (2007) (1)
- The chivalrous pigeon: Pigeons help their mates to obtain resources (1987) (1)
- Strength in numbers. (2002) (1)
- Comparative Genomics: Genomes of mice and men (2003) (1)
- Unusual recombinant HLA-B alleles in a tribe of South American Amerindians (1992) (1)
- Interallellc recombination has not played a major role In the history of theHLA-C locus (2007) (1)
- Dblox: a genome-wide test for ancient segmental duplication (2004) (1)
- Reply from austin hughes. (1992) (1)
- Letter to Blood To the editor: Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function (2017) (0)
- Electrical Recording of Drinking Behavior by the Housefly, Musca Domestica (2015) (0)
- HLA-A∗8001 is a member of a new family of HLA-A alleles (1994) (0)
- 10.1534/genetics.104.032979 Patterns of Sequence Divergence in 5 (cid:1) Intergenic Spacers and Linked Coding Regions in 10 Species of Pathogenic Bacteria Reveal Distinct Recombinational (2004) (0)
- Coevolution of Body Form and Reproductive Effort in Shorebirds (Aves: Charadriiformes) (2015) (0)
- Being in the thick of things: context-dependent network centrality in a captive flock of American flamingos (2014) (0)
- Purifying Selection (Negative Selection) (2014) (0)
- Comparative genomics: Mining the crucial 1% (2004) (0)
- Malaria Parasites: Genomes and Molecular Biology: A.P. Waters, C.J. Janse (Eds.), Academic Press, Wymondham, Norfolk, UK, 2004 (2004) (0)
- Coevolution of Body Form and Reproductive Effort in Shorebirds (Aves: Charadriiformes) (2015) (0)
- Book Review:Of Mice, Men, and Microbes: Hantavirus David R. Harper, Andrea S. Meyer (2001) (0)
- Protein in a Wild Old World Primate Long and Intrinsically Disordered NS5A A Novel Hepacivirus with an Unusually (2014) (0)
- Evolutionary diversification of the vertebrate transferrin multi-gene family (2014) (0)
- Evolution of the βGRP/GNBP/β-1,3-glucanase family of insects (2012) (0)
- AIDS virus – specifi c CD8 (cid:2) T lymphocytes against an immunodominant cryptic epitope select for viral escape (2007) (0)
- InfectionSimian Immunodeficiency Virus T Cell Escape during + Conditional CD8 (2014) (0)
- Sequence and Evolution of Bovine MHC Class I Genes (1991) (0)
- Parallel evolution by gene duplication in the genomes of two unicellular fungi. (2003) (0)
- Maintenance of DQBl Polymorphisms in Primates ’ (1998) (0)
- Rapid Evolution Immune System (1998) (0)
- Contrasting Patterns of Transcript Abundance in Tumour Tissue and Cancer Cell Lines (2006) (0)
- Evolutionary analysis of molecular sequence data (2001) (0)
- Faculty Opinions recommendation of Temporal fragmentation of speciation in bacteria. (2007) (0)
- Between-Host Evolution of Cytotoxic T-Lymphocyte Epitopes in Human Immunodeficiency Virus Type 1: an Approach Based on Phylogenetically Independent Comparisons (2005) (0)
- P702 - MHC class I genes in new world primates (1996) (0)
- Supplemental Information Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian In fl uenza Virus (0)
- Evolution of supraorbital ossification in Charadriiformes (2015) (0)
- More word play (1993) (0)
- Evolutionary Diversifaction of Aminopeptidase N in Lepidoptera by Conserved Clade-specific Amino Acid Residues (2015) (0)
- Gene Loss and Inactivation (Gene Inactivation) (2004) (0)
- Faculty Opinions recommendation of Community-wide convergent evolution in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase. (2012) (0)
- Virus-Infected Macaques Escape in Simian Immunodeficiency T-Lymphocyte + Complex Patterns of CD8 Ultradeep Pyrosequencing Detects (2014) (0)
- Faculty Opinions recommendation of Deep sequencing of HPV16 genomes: A new high-throughput tool for exploring the carcinogenicity and natural history of HPV16 infection. (2015) (0)
- Faculty Opinions recommendation of Multiple independent introductions of Plasmodium falciparum in South America. (2012) (0)
- Cross-clade simultaneous HIV drug resistance genotyping for reverse transcriptase, protease, and integrase inhibitor mutations by Illumina MiSeq (2014) (0)
- Horizontal Gene Transfer (2004) (0)
- MacaquesAlleles in Mauritian Origin Cynomolgus Unusually High Frequency MHC Class I (2005) (0)
- Positive Darwinian Selection (Positive Selection) (2004) (0)
- Evolution of Great Ape MHC Class I Genes (1991) (0)
- Selective and Structural Constraints (2006) (0)
- Sexual Selection and Mate Choice: Insights from Neutralist Perspectives (2015) (0)
- Female Reproductive Effort and Sexual Selection on Males of Waterfowl (2012) (0)
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What Schools Are Affiliated With Austin L. Hughes?
Austin L. Hughes is affiliated with the following schools:
