Aviv Regev
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Bioinformatician
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Aviv Regevbiology Degrees
Biology
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Computational Biology
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Bioinformatics
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Biology
Aviv Regev's Degrees
- PhD Computational Biology Tel Aviv University
- Bachelors Computer Science and Biology Tel Aviv University
Why Is Aviv Regev Influential?
(Suggest an Edit or Addition)According to Wikipedia, Aviv Regev is a computational biologist and systems biologist and Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche. She is a core member at the Broad Institute of MIT and Harvard and professor at the Department of Biology of the Massachusetts Institute of Technology. Regev is a pioneer of single cell genomics and of computational and systems biology of gene regulatory circuits. She founded and leads the Human Cell Atlas project, together with Sarah Teichmann.
Aviv Regev's Published Works
Published Works
- Full-length transcriptome assembly from RNA-Seq data without a reference genome. (2011) (12944)
- De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis (2013) (5897)
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets (2015) (5020)
- Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals (2009) (3820)
- Trinity: reconstructing a full-length transcriptome without a genome from RNA-Seq data (2011) (3744)
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma (2014) (3192)
- Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. (2011) (3061)
- Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System (2015) (2978)
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq (2016) (2825)
- Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression (2009) (2770)
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors (2008) (2387)
- Spatial reconstruction of single-cell gene expression (2015) (2128)
- A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response (2010) (1942)
- SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues (2020) (1833)
- lincRNAs act in the circuitry controlling pluripotency and differentiation (2011) (1827)
- Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data (2003) (1826)
- SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes (2020) (1723)
- Nucleic acid detection with CRISPR-Cas13a/C2c2 (2017) (1699)
- Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors (2017) (1554)
- CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling (2014) (1395)
- Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium (2010) (1342)
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector (2016) (1335)
- The Human Cell Atlas (2017) (1285)
- Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer (2017) (1265)
- Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs (2010) (1233)
- Spatial reconstruction of single-cell gene expression data (2015) (1120)
- RNA targeting with CRISPR–Cas13 (2017) (1116)
- Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells (2013) (1096)
- An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma (2019) (1007)
- Induction and molecular signature of pathogenic TH17 cells (2012) (956)
- A single-cell survey of the small intestinal epithelium (2017) (954)
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens (2016) (920)
- SOX2 Is an Amplified Lineage Survival Oncogene in Lung and Esophageal Squamous Cell Carcinomas (2009) (904)
- Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis (2011) (887)
- A unique regulatory phase of DNA methylation in the early mammalian embryo (2012) (886)
- Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics (2016) (856)
- Single cell RNA Seq reveals dynamic paracrine control of cellular variation (2014) (848)
- Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1 (2013) (846)
- Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. (2014) (836)
- Ab initio reconstruction of transcriptomes of pluripotent and lineage committed cells reveals gene structures of thousands of lincRNAs (2010) (779)
- CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq (2016) (761)
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (754)
- Comprehensive comparative analysis of strand-specific RNA sequencing methods (2010) (740)
- Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis. (2012) (739)
- A module map showing conditional activity of expression modules in cancer (2004) (739)
- Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma (2016) (731)
- Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells (2014) (712)
- A revised airway epithelial hierarchy includes CFTR-expressing ionocytes (2018) (710)
- Massively-parallel single nucleus RNA-seq with DroNc-seq (2017) (689)
- Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA (2014) (679)
- A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response (2016) (678)
- A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade (2018) (673)
- A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection (2009) (654)
- Natural history and evolutionary principles of gene duplication in fungi (2007) (640)
- Dynamic regulatory network controlling Th17 cell differentiation (2013) (626)
- Inferring subnetworks from perturbed expression profiles (2001) (615)
- Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region (2018) (614)
- Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq (2017) (612)
- Landscape of X chromosome inactivation across human tissues (2016) (596)
- The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism (2012) (580)
- Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis (2019) (572)
- A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. (2017) (550)
- BioAmbients: an abstraction for biological compartments (2004) (547)
- Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution (2015) (530)
- Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells (2011) (526)
- Representation and Simulation of Biochemical Processes Using the pi-Calculus Process Algebra (2000) (519)
- Scaling single-cell genomics from phenomenology to mechanism (2017) (518)
- Application of a stochastic name-passing calculus to representation and simulation of molecular processes (2001) (514)
- High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis (2013) (512)
- Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis (2018) (503)
- High-definition spatial transcriptomics for in situ tissue profiling (2019) (496)
- Individual brain organoids reproducibly form cell diversity of the human cerebral cortex (2019) (495)
- High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome Profiling (2011) (494)
- Electrical and synaptic integration of glioma into neural circuits (2019) (491)
- Proto-genes and de novo gene birth (2012) (491)
- Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells (2015) (489)
- Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses (2009) (483)
- Whole exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer (2014) (479)
- DNA methylation dynamics of the human preimplantation embryo (2014) (475)
- Revealing the vectors of cellular identity with single-cell genomics (2016) (471)
- A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia (2019) (466)
- Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes (2014) (466)
- Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity (2015) (460)
- Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution (2017) (442)
- Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing (2014) (439)
- Comparative Functional Genomics of the Fission Yeasts (2011) (439)
- Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons (2016) (426)
- De novo transcript sequence reconstruction from RNA-Seq: reference generation and analysis with Trinity (2013) (421)
- The Human Cell Atlas: from vision to reality (2017) (417)
- From signatures to models: understanding cancer using microarrays (2005) (409)
- The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation (2017) (407)
- Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells (2014) (383)
- Dynamic profiling of the protein life cycle in response to pathogens (2015) (381)
- A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks (2015) (380)
- Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma (2019) (376)
- Many lncRNAs, 5’UTRs, and pseudogenes are translated and some are likely to express functional proteins (2015) (372)
- Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (368)
- Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq (2018) (368)
- Chromatin signature of embryonic pluripotency is established during genome activation (2010) (368)
- Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. (2004) (368)
- A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. (2012) (367)
- Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin (2020) (363)
- Disease-associated astrocytes in Alzheimer’s disease and aging (2020) (363)
- COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets (2021) (347)
- Single-cell transcriptomics to explore the immune system in health and disease (2017) (335)
- Deconstructing transcriptional heterogeneity in pluripotent stem cells (2014) (335)
- Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD‐1−CD8+ Tumor‐Infiltrating T Cells (2019) (334)
- Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells (2011) (328)
- Mitochondrial dysfunction remodels one-carbon metabolism in human cells (2015) (324)
- Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples (2013) (314)
- A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease (2018) (307)
- Decoding human fetal liver haematopoiesis (2019) (303)
- Single-cell transcriptomic profiling of the aging mouse brain (2019) (296)
- Cellular abstractions: Cells as computation (2002) (296)
- Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming (2019) (290)
- Conservation and divergence in the transcriptional programs of the human and mouse immune systems (2013) (279)
- A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells (2016) (275)
- Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods (2019) (273)
- Conservation and evolvability in regulatory networks: the evolution of ribosomal regulation in yeast. (2005) (273)
- Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina (2018) (271)
- Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics (2019) (271)
- Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes (2019) (269)
- Induction and transcriptional regulation of the co-inhibitory gene module in T cells (2018) (266)
- The human body at cellular resolution: the NIH Human Biomolecular Atlas Program (2019) (265)
- CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity (2015) (265)
- The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells (2014) (264)
- Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6 (2017) (258)
- Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. (2014) (249)
- Distinct physiological states of Plasmodium falciparum in malaria-infected patients (2007) (246)
- Ribosome profiling reveals resemblance between long non-coding RNAs and 5′ leaders of coding RNAs (2013) (245)
- A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors (2019) (242)
- Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis (2018) (241)
- Ab initio construction of a eukaryotic transcriptome by massively parallel mRNA sequencing (2009) (237)
- The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
- Structure and function of a transcriptional network activated by the MAPK Hog1 (2008) (234)
- High-resolution interrogation of functional elements in the noncoding genome (2016) (234)
- Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease (2020) (231)
- Molecular definition of the identity and activation of natural killer cells (2012) (230)
- Impulse Control: Temporal Dynamics in Gene Transcription (2011) (229)
- Mutations causing medullary cystic kidney disease type 1 (MCKD1) lie in a large VNTR in MUC1 missed by massively parallel sequencing (2013) (228)
- The evolution of drug resistance in clinical isolates of Candida albicans (2015) (227)
- The microbiota regulate neuronal function and fear extinction learning (2019) (227)
- Preparation of Single‐Cell RNA‐Seq Libraries for Next Generation Sequencing (2014) (225)
- Dynamic single-cell imaging of direct reprogramming reveals an early specifying event (2010) (219)
- Intersection of population variation and autoimmunity genetics in human T cell activation (2014) (219)
- Synergistic activity of a Bacillus thuringiensis delta-endotoxin and a bacterial endochitinase against Spodoptera littoralis larvae (1996) (217)
- Inferring quantitative models of regulatory networks from expression data (2004) (215)
- The Role of Nucleosome Positioning in the Evolution of Gene Regulation (2010) (215)
- Early-branching gut fungi possess a large, comprehensive array of biomass-degrading enzymes (2016) (214)
- Resolving medulloblastoma cellular architecture by single-cell genomics (2019) (213)
- CRISPR EVOLUTION C 2 c 2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector (2016) (207)
- Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19 (2020) (205)
- Parsing the Interferon Transcriptional Network and Its Disease Associations (2016) (201)
- Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming (2019) (200)
- The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas (2017) (196)
- STAR-Fusion: Fast and Accurate Fusion Transcript Detection from RNA-Seq (2017) (195)
- Transcriptional Regulatory Circuits: Predicting Numbers from Alphabets (2009) (190)
- A multimodal cell census and atlas of the mammalian primary motor cortex (2020) (190)
- High-Resolution Sequencing and Modeling Identifies Distinct Dynamic RNA Regulatory Strategies (2014) (189)
- A single-cell landscape of high-grade serous ovarian cancer (2020) (184)
- Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits (2011) (182)
- Comparative cellular analysis of motor cortex in human, marmoset and mouse (2021) (177)
- Identification of transcriptional regulators in the mouse immune system (2013) (175)
- The Human and Mouse Enteric Nervous System at Single-Cell Resolution (2020) (175)
- A Generic and Cell-Type-Specific Wound Response Precedes Regeneration in Planarians. (2015) (175)
- Learning Module Networks (2002) (175)
- Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network (2008) (174)
- Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML (2016) (173)
- A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. (2015) (169)
- Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia (2012) (165)
- Automatic genome-wide reconstruction of phylogenetic gene trees (2007) (157)
- Systematic Dissection of Roles for Chromatin Regulators in a Yeast Stress Response (2012) (156)
- Induction of pathogenic Th 17 cells by inducible salt sensing kinase SGK 1 (2013) (154)
- The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense? (1998) (151)
- Digestion of delta-endotoxin by gut proteases may explain reduced sensitivity of advanced instar larvae of Spodoptera littoralis to CryIC. (1996) (147)
- Strand-specific RNA sequencing reveals extensive regulated long antisense transcripts that are conserved across yeast species (2010) (147)
- Benchmarking single-cell RNA-sequencing protocols for cell atlas projects (2020) (147)
- Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma. (2021) (146)
- Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems (2020) (144)
- snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis (2020) (144)
- Deciphering eukaryotic gene-regulatory logic with 100 million random promoters (2017) (144)
- Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells (2021) (142)
- Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma (2021) (142)
- Single Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations. (2019) (142)
- Nucleic acid detection with CRISPR-Cas 13 a / C 2 c 2 Citation (2017) (138)
- The Human Lung Cell Atlas - A high-resolution reference map of the human lung in health and disease. (2019) (138)
- Emergence of a High-Plasticity Cell State during Lung Cancer Evolution. (2020) (138)
- Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses (2015) (138)
- Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies (2018) (136)
- Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity (2020) (134)
- RNA targeting with CRISPR-Cas 13 a (2017) (134)
- Dissecting Timing Variability in Yeast Meiosis (2007) (133)
- Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis (2021) (132)
- Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers (2019) (131)
- Comparative analysis of gene regulatory networks: from network reconstruction to evolution. (2015) (129)
- IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment (2017) (129)
- Cycling cancer persister cells arise from lineages with distinct programs (2021) (129)
- Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs (2016) (127)
- Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram (2021) (126)
- Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction (2016) (125)
- Purine synthesis promotes maintenance of brain tumor initiating cells in glioma (2017) (125)
- Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA (2010) (123)
- Regenerative potential of prostate luminal cells revealed by single-cell analysis (2020) (121)
- Benchmarking single-cell RNA-sequencing protocols for cell atlas projects (2019) (120)
- AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia (2017) (118)
- In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes (2019) (112)
- Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. (2019) (111)
- Corrigendum: Comparative analysis of RNA sequencing methods for degraded or low-input samples (2013) (110)
- Metabolic modeling of single Th17 cells reveals regulators of autoimmunity (2021) (110)
- Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses. (2019) (109)
- Spatially organized multicellular immune hubs in human colorectal cancer (2021) (109)
- Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq (2018) (107)
- Cell Atlas of The Human Fovea and Peripheral Retina (2020) (105)
- Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses (2015) (105)
- Molecular logic of cellular diversification in the mouse cerebral cortex (2021) (105)
- Genetic determinants of co-accessible chromatin regions in activated T cells across humans (2018) (103)
- A cellular and spatial map of the choroid plexus across brain ventricles and ages (2019) (103)
- Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation (2019) (103)
- Nuclei multiplexing with barcoded antibodies for single-nucleus genomics (2018) (97)
- YMAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens (2014) (96)
- Genome-wide identification and characterization of replication origins by deep sequencing (2012) (95)
- Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling (2020) (94)
- A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex (2021) (94)
- Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma. (2020) (93)
- Systematic comparative analysis of single cell RNA-sequencing methods (2019) (93)
- A single-cell atlas of human and mouse white adipose tissue (2021) (92)
- Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells (2013) (92)
- The π-calculus as an Abstraction for Biomolecular Systems (2004) (92)
- Hyperactivation of Sympathetic Nerves Drives Melanocyte Stem Cell Depletion (2019) (89)
- Small polydispersed circular DNA (spcDNA) in human cells: association with genomic instability (1997) (89)
- Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli are Altered with Age (2017) (89)
- Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function (2022) (88)
- Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation (2017) (87)
- Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis (2019) (87)
- Autism genes converge on asynchronous development of shared neuron classes (2022) (86)
- RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression. (2016) (86)
- Minreg: Inferring an active regulator set (2002) (86)
- Efficient Generation of Transcriptomic Profiles by Random Composite Measurements (2017) (85)
- The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression. (2015) (84)
- Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq (2020) (84)
- Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia (2012) (84)
- TIM-3 restrains anti-tumour immunity by regulating inflammasome activation (2021) (83)
- Evolutionary divergence of intrinsic and trans-regulated nucleosome positioning sequences reveals plastic rules for chromatin organization. (2011) (83)
- The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments (2021) (83)
- Evolutionary principles of modular gene regulation in yeasts (2013) (81)
- Comparative analysis of mycobacterium and related actinomycetes yields insight into the evolution of mycobacterium tuberculosis pathogenesis (2012) (80)
- Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata (2012) (80)
- Determinants of Divergent Adaptation and Dobzhansky-Muller Interaction in Experimental Yeast Populations (2010) (77)
- Gene duplication and the evolution of ribosomal protein gene regulation in yeast (2010) (77)
- Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action (2020) (76)
- Cellular and inter-cellular rewiring of the human colon during ulcerative colitis (2019) (75)
- Comprehensive comparative analysis of 5’ end RNA sequencing methods (2018) (72)
- Skin-resident innate lymphoid cells converge on a pathogenic effector state (2021) (72)
- Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL. (2012) (71)
- Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate. (2019) (70)
- Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis (2020) (69)
- Transcriptional mediators of treatment resistance in lethal prostate cancer (2020) (69)
- Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma (2020) (68)
- Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming (2017) (67)
- Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells (2020) (67)
- LAMP-Seq: Population-Scale COVID-19 Diagnostics Using Combinatorial Barcoding (2020) (67)
- Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases (2020) (66)
- Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion (2021) (66)
- Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse (2020) (66)
- An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types (2020) (66)
- Digital transcriptome profiling from attomole-level RNA samples. (2010) (65)
- Telomeric repeats on small polydisperse circular DNA (spcDNA) and genomic instability (1998) (64)
- Further enhancement of baculovirus insecticidal efficacy with scorpion toxins that interact cooperatively (2003) (64)
- L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma (2020) (63)
- Spatial components of molecular tissue biology (2022) (63)
- Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment. (2020) (63)
- The Organoid Cell Atlas (2020) (62)
- A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types (2021) (62)
- Extracellular Vesicle Isolation and Analysis by Western Blotting. (2017) (61)
- Mouse ooplasm confers context-specific reprogramming capacity (2012) (60)
- The evolution, evolvability and engineering of gene regulatory DNA (2022) (60)
- Changes in nucleosome occupancy associated with metabolic alterations in aged mammalian liver. (2014) (59)
- Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states (2021) (58)
- Molecular analysis of transitional cell carcinoma using cDNA microarray (2003) (58)
- Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer (2021) (58)
- A roadmap for the Human Developmental Cell Atlas (2021) (57)
- B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV (2021) (57)
- Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes. (2020) (57)
- Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus (2022) (57)
- Revealing targeted therapy for human cancer by gene module maps. (2008) (57)
- A quantitative framework for characterizing the evolutionary history of mammalian gene expression (2018) (56)
- Strategies to discover regulatory circuits of the mammalian immune system (2011) (55)
- ImmVar project: Insights and design considerations for future studies of "healthy" immune variation. (2015) (55)
- The Human Cell Atlas White Paper (2018) (55)
- CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours (2022) (55)
- Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps (2021) (55)
- Toward a Common Coordinate Framework for the Human Body (2019) (53)
- MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging (2021) (53)
- DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical Reaction (2018) (52)
- The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. (2021) (51)
- A transgenic mouse marking live replicating cells reveals in vivo transcriptional program of proliferation. (2012) (50)
- Arboretum: Reconstruction and analysis of the evolutionary history of condition-specific transcriptional modules (2013) (50)
- BioPAX - Biological Pathways Exchange Language Level 2, Version 1.0 Documentation (2005) (50)
- Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer (2019) (50)
- From elements to modules: regulatory evolution in Ascomycota fungi. (2009) (48)
- A functional selection model explains evolutionary robustness despite plasticity in regulatory networks (2012) (48)
- The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. (2019) (48)
- Writ large: Genomic dissection of the effect of cellular environment on immune response (2016) (47)
- Physical Module Networks: an integrative approach for reconstructing transcription regulation (2011) (47)
- Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace (2015) (47)
- An exact arithmetic toolbox for a consistent and reproducible structural analysis of metabolic network models (2014) (46)
- Pluripotency Transcription Factor Oct4 Mediates Stepwise Nucleosome Demethylation and Depletion (2015) (46)
- γδ T cells regulate the intestinal response to nutrient sensing (2021) (46)
- Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection (2017) (45)
- Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer (2019) (45)
- Deep generative model embedding of single-cell RNA-Seq profiles on hyperspheres and hyperbolic spaces (2019) (45)
- Single‐Cell, Single‐Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity (2021) (44)
- Pathophysiology and fate of hepatocytes in a mouse model of mitochondrial hepatopathies (2007) (44)
- Oct1 and OCA-B are selectively required for CD4 memory T cell function (2015) (44)
- Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity (2021) (44)
- Transcriptome-scale RNase-footprinting of RNA-protein complexes (2015) (43)
- GeNets: A unified web platform for network-based analyses of genomic data (2018) (43)
- Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1 (2018) (42)
- Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli (2013) (42)
- The transcriptional landscape of ab T cell differentiation (2013) (42)
- Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes. (2021) (42)
- IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development. (2019) (41)
- A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq. (2020) (40)
- Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing (2020) (40)
- Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells. (2020) (39)
- Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity (2016) (39)
- MinReg: A Scalable Algorithm for Learning Parsimonious Regulatory Networks in Yeast and Mammals (2006) (39)
- A transcriptomic atlas of the mouse cerebellum reveals regional specializations and novel cell types (2020) (39)
- Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy (2022) (38)
- QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis (2021) (37)
- Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors (2021) (37)
- Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma (2021) (37)
- PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes (2017) (37)
- Cell type ontologies of the Human Cell Atlas (2021) (36)
- Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment (2022) (35)
- RNA-Seq methods for imperfect samples: development, evaluation and applications (2011) (35)
- EZH2 promotes a bi-lineage identity in basal-like breast cancer cells (2012) (35)
- Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer (2020) (35)
- Towards a Human Cell Atlas: Taking Notes from the Past. (2021) (34)
- Joint single-cell measurements of nuclear proteins and RNA in vivo (2021) (34)
- Regulation of X-linked gene expression during early mouse development by Rlim (2016) (34)
- Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features (2020) (34)
- Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with Tangram (2020) (34)
- LAMP-Seq: Population-Scale COVID-19 Diagnostics Using a Compressed Barcode Space (2020) (33)
- MetaMerge: scaling up genome-scale metabolic reconstructions with application to Mycobacterium tuberculosis (2012) (33)
- BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization (2018) (33)
- LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding (2021) (32)
- Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis. (2021) (32)
- Streamlined Protocol for Deep Proteomic Profiling of FAC-sorted Cells and Its Application to Freshly Isolated Murine Immune Cells* (2019) (31)
- A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2 (2021) (30)
- Perturbation of m 6 AWriters Reveals Two Distinct Classes of mRNA Methylation at Internal and 5 0 Sites (2014) (30)
- An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets (2020) (30)
- Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells (2019) (30)
- Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment (2020) (29)
- Induction and molecular signature of pathogenic T[subscript H]17 cells (2012) (29)
- Regulation of Cellular Heterogeneity and Rates of Symmetric and Asymmetric Divisions in Triple-Negative Breast Cancer. (2018) (29)
- Blood and immune development in human fetal bone marrow and Down syndrome (2021) (29)
- The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis (2020) (28)
- Revisiting the Saccharomyces cerevisiae predicted ORFeome. (2008) (28)
- Building a high-quality Human Cell Atlas (2021) (27)
- Fungal regulatory evolution: cis and trans in the balance (2009) (27)
- A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies (2021) (26)
- RNA-Seq methods for imperfect samples: development, evaluation and applications (2011) (26)
- DroNc-Seq: Deciphering cell types in human archived brain tissues by massively-parallel single nucleus RNA-seq (2017) (26)
- A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest (2020) (25)
- Multi-cellular communities are perturbed in the aging human brain and Alzheimer’s disease (2020) (25)
- Combinatorial prediction of marker panels from single-cell transcriptomic data (2019) (25)
- High-density spatial transcriptomics arrays for in situ tissue profiling (2019) (24)
- Using viral load and epidemic dynamics to optimize pooled testing in resource-constrained settings (2021) (24)
- SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes (2020) (24)
- Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics (2021) (24)
- Single-nucleus cross-tissue molecular reference maps to decipher disease gene function (2021) (23)
- New measures of insecticidal efficacy and safety obtained with the 39K promoter of a recombinant baculovirus (2006) (23)
- SMARCA4 inactivation promotes lineage-specific transformation and early metastatic features in the lung. (2021) (23)
- Combinatorial prediction of marker panels from single‐cell transcriptomic data (2019) (23)
- Inference and Evolutionary Analysis of Genome-Scale Regulatory Networks in Large Phylogenies. (2017) (23)
- Compressed sensing for highly efficient imaging transcriptomics (2021) (22)
- Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC (2021) (22)
- Transcriptional Profiling of Plasmodium falciparum Parasites from Patients with Severe Malaria Identifies Distinct Low vs. High Parasitemic Clusters (2012) (22)
- The CD155/TIGIT Axis Promotes and Maintains Immune Evasion in Neoantigen-Expressing Pancreatic Cancer (2020) (22)
- Module Networks : Discovering Regulatory Modules and their Condition Specific Regulators from Gene Expression Data (2003) (22)
- SM-Omics is an automated platform for high-throughput spatial multi-omics (2020) (22)
- An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling. (2017) (21)
- Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity (2021) (21)
- Using viral load and epidemic dynamics to optimize pooled testing in resource constrained settings (2020) (21)
- A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain (2018) (21)
- Skin inflammation driven by differentiation of quiescent tissue-resident ILCs into a spectrum of pathogenic effectors (2018) (21)
- ImmGen at 15 (2020) (21)
- Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing (2017) (21)
- GeNets: a unified web platform for network-based genomic analyses (2018) (20)
- Rewiring of the cellular and inter-cellular landscape of the human colon during ulcerative colitis (2018) (19)
- Streamlined Protocol for Deep Proteomic Profiling of FAC-sorted Cells and Its Application to Freshly Isolated Murine Immune Cells. (2019) (19)
- Massively parallel phenotyping of coding variants in cancer with Perturb-seq (2022) (19)
- Efficient prevalence estimation and infected sample identification with group testing for SARS-CoV-2 (2020) (19)
- Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity (2018) (19)
- Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics (2022) (18)
- The enteric nervous system of the human and mouse colon at a single-cell resolution (2019) (18)
- Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation (2018) (18)
- Simultaneous single cell measurements of intranuclear proteins and gene expression (2021) (18)
- Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis (2022) (17)
- An integrated taxonomy for monogenic inflammatory bowel disease. (2021) (17)
- Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortex (2022) (17)
- Pan-cancer single cell RNA-seq uncovers recurring programs of cellular heterogeneity (2019) (17)
- Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1 (2019) (17)
- Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function. (2021) (17)
- Scalable, multimodal profiling of chromatin accessibility and protein levels in single cells (2020) (16)
- Correction: Corrigendum: Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs (2010) (16)
- DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data (2022) (16)
- MAUDE: inferring expression changes in sorting-based CRISPR screens (2019) (15)
- Enforcement of developmental lineage specificity by transcription factor Oct1 (2017) (15)
- Imaging of Isolated Extracellular Vesicles Using Fluorescence Microscopy. (2017) (15)
- GeneXPress : A Visualization and Statistical Analysis Tool for Gene Expression and Sequence Data (15)
- Impact of the Human Cell Atlas on medicine (2022) (15)
- Functional Genomics of Lung Disease (2004) (15)
- Molecular Logic of Cellular Diversification in the Mammalian Cerebral Cortex (2020) (15)
- The legacy of the Human Genome Project. (2021) (15)
- Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing (2022) (15)
- SM-Omics is an automated platform for high-throughput spatial multi-omics (2022) (14)
- A microRNA expression and regulatory element activity atlas of the mouse immune system (2021) (14)
- Gene number, methylation and biological complexity. (1995) (13)
- Semiconductor-based DNA sequencing of histone modification states (2013) (13)
- In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and Autoimmunity (2020) (13)
- Semaphorin-4D (Sema-4D), the Plexin-B1 ligand, is involved in mouse ovary follicular development (2007) (13)
- Expression of plexin-B1 in the mouse ovary and its possible role in follicular development. (2005) (12)
- Cumulus: a cloud-based data analysis framework for large-scale single-cell and single-nucleus RNA-seq (2019) (12)
- Mapping of the entomocidal fragment of Spodoptera-specific Bacillus thuringiensis toxin CryIC (1996) (12)
- Patel glioblastoma Single-cell RNA-seq highlights intratumoral heterogeneity in primary (2014) (12)
- A human breast atlas integrating single-cell proteomics and transcriptomics. (2022) (11)
- A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery (2021) (11)
- Cycling cancer persister cells arise from lineages with distinct transcriptional and metabolic programs (2020) (11)
- Stepwise-edited, human melanoma models reveal mutations’ effect on tumor and microenvironment (2022) (11)
- Div-Seq: A single nucleus RNA-Seq method reveals dynamics of rare adult newborn neurons in the CNS (2016) (11)
- Unbiased reconstruction of a mammalian transcriptional network mediating the differential response to pathogens (2009) (10)
- An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes. (2022) (10)
- Author response: The Human Cell Atlas (2017) (10)
- The network effect: studying COVID-19 pathology with the Human Cell Atlas (2020) (10)
- Composite measurements and molecular compressed sensing for highly efficient transcriptomics (2017) (10)
- On the growth of identities (2000) (10)
- scSVA: an interactive tool for big data visualization and exploration in single-cell omics (2019) (10)
- Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes (2020) (10)
- A molecular network of the aging brain implicates INPPL1 and PLXNB1 in Alzheimer’s disease (2017) (9)
- Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutations (2020) (9)
- Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex (2022) (9)
- Single-cell transcriptomics of the aged mouse brain reveals convergent, divergent and unique aging signatures (2018) (9)
- Single-nucleus RNA-Seq reveals a new type of brown adipocyte regulating thermogenesis (2020) (9)
- Aging-associated alterations in the mammary gland revealed by single-cell RNA sequencing (2019) (9)
- Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics (2019) (9)
- Pancreatic cancer risk predicted from disease trajectories using deep learning (2021) (9)
- Development and evaluation of RNA-seq methods (2010) (9)
- EquiFold: Protein Structure Prediction with a Novel Coarse-Grained Structure Representation (2023) (9)
- Correction: Evolutionary principles of modular gene regulation in yeasts (2013) (9)
- Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion (2021) (9)
- Perturbation of m 6 A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5 Sites Citation (2014) (9)
- , I against Spodoptera littoralis larvae . delta-endotoxin and a bacterial endochitinase Synergistic activity of a Bacillus thuringiensis (1996) (8)
- A quantitative model for characterizing the evolutionary history of mammalian gene expression (2017) (8)
- In vivo profiles in malaria are consistent with a novel physiological state (2009) (8)
- Reply to “Do genome-scale models need exact solvers or clearer standards?” (2015) (8)
- GenomeSpace: an environment for frictionless bioinformatics (2013) (8)
- Compressed sensing for imaging transcriptomics (2019) (8)
- A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1. (2022) (8)
- Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium (2022) (8)
- RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells (2020) (8)
- Author Correction: A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors (2020) (7)
- Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs (2015) (7)
- Erratum: The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation (2017) (7)
- Mapping multicellular programs from single-cell profiles (2020) (7)
- A transcription factor atlas of directed differentiation (2023) (7)
- The necessity and power of random, under-sampled experiments in biology (2020) (7)
- Single-cell multimodal profiling of proteins and chromatin accessibility using PHAGE-ATAC (2020) (7)
- Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function (2022) (7)
- Corrigendum: Landscape of X chromosome inactivation across human tissues (2018) (7)
- BRNI: Modular analysis of transcriptional regulatory programs (2009) (7)
- Large-Scale Differentiable Causal Discovery of Factor Graphs (2022) (7)
- Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing (2022) (6)
- T Follicular Regulatory Cell–Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity (2020) (6)
- Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. (2022) (6)
- Metabolic and Epigenomic Regulation of Th17/Treg Balance by the Polyamine Pathway (2020) (6)
- Genetic determinants of co-accessible chromatin regions in T cell activation across humans (2017) (6)
- BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization (2017) (6)
- Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion (2020) (6)
- Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (6)
- Single Cell, Single Nucleus and Spatial RNA Sequencing of the Human Liver Identifies Hepatic Stellate Cell and Cholangiocyte Heterogeneity (2021) (6)
- Single-cell profiles of retinal neurons differing in resilience to injury reveal neuroprotective genes (2019) (5)
- A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest. (2020) (5)
- SnFFPE-Seq: towards scalable single nucleus RNA-Seq of formalin-fixed paraffin-embedded (FFPE) tissue (2022) (5)
- Three-dimensional spatial transcriptomics uncovers cell type dynamics in the rheumatoid arthritis synovium (2020) (5)
- AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer (2022) (5)
- Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (5)
- Novel Germline Genetic Variants Associated with Familial Chronic Lymphocytic Leukemia (CLL) (2011) (5)
- GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome (2021) (5)
- Obesity-instructed TREM2high macrophages identified by comparative analysis of diabetic mouse and human kidney at single cell resolution (2021) (5)
- Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma (2020) (5)
- A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia (2021) (5)
- The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8[superscript +] T cells (2014) (5)
- A comprehensive fitness landscape model reveals the evolutionary history and future evolvability of eukaryotic cis-regulatory DNA sequences (2021) (5)
- Integrative single cell and spatial transcriptomics of colorectal cancer reveals multicellular functional units that support tumor progression (2022) (5)
- JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia. (2022) (5)
- Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias (2021) (5)
- Genetic determinants of chromatin accessibility and gene regulation in T cell activation across human individuals (2016) (5)
- Economic evaluation of the transition from a traditional to a modernized irrigation project (1990) (5)
- Multiplexed single-cell profiling of post-perturbation transcriptional responses to define cancer vulnerabilities and therapeutic mechanism of action (2019) (5)
- The Organoid Cell Atlas: A Rosetta Stone for Biomedical Discovery and Regenerative Therapy (2020) (4)
- A Synthesis Concerning Conservation and Divergence of Cell Types across Epithelia. (2020) (4)
- Voices of biotech (2016) (4)
- Decoding the development of the blood and immune systems during human fetal liver haematopoiesis (2019) (4)
- Power analysis for spatial omics (2022) (4)
- Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity (2021) (4)
- Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells (2020) (4)
- Learning Causal Representations of Single Cells via Sparse Mechanism Shift Modeling (2022) (4)
- 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. (2016) (4)
- Reconstructing gene histories in Ascomycota fungi. (2010) (4)
- A SINGLE-CELL-BASED ATLAS OF HUMAN MICROGLIAL STATES SHOWS DIVERGENT ASSOCIATIONS WITH AGING-RELATED NEUROPATHOLOGIES AND DEMENTIA (2018) (4)
- T helper cells modulate intestinal stem cell renewal and differentiation (2017) (4)
- Raman2RNA: Live-cell label-free prediction of single-cell RNA expression profiles by Raman microscopy (2021) (4)
- Effect of androgen substrates on the steroidogenic pattern of cumulus cells: Correlation with cumulus culture morphology (1997) (4)
- Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology (2019) (3)
- Abstract 5631: Personal neoantigen-targeting vaccination generates neoepitope-specific T cell responses in tumors of patients with glioblastoma (2018) (3)
- Integrated regulatory models for inference of subtype‐specific susceptibilities in glioblastoma (2020) (3)
- Cell Atlas of Aqueous Humor Outflow Pathways in Eyes of Humans and Four Model Species Provides Insights into Glaucoma Pathogenesis (2020) (3)
- Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex (2022) (3)
- Reconstructing probabilistic trees of cellular differentiation from single-cell RNA-seq data (2018) (3)
- Abstract CN07-04: Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq (2015) (3)
- RPS15 and TP53 Co-Mutation Drives B Cell Malignancy through Altered Translation and MYC Activation in a Murine Model (2020) (3)
- Abstract PR06: Contribution of mutant microenvironment to hereditary cancer: Single-cell gene expression profiling of a genetically engineered mouse model of human hereditary BRCA1-related breast cancer (2018) (3)
- Erratum: Comparative analysis of RNA sequencing methods for degraded or low-input samples (Nature Methods (2013) 10 (623-629 ) (2014) (3)
- Targeted in silico characterization of fusion transcripts in tumor and normal tissues via FusionInspector (2021) (3)
- A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types (2021) (3)
- CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq (2016) (3)
- TACCO: Unified annotation transfer and decomposition of cell identities for single-cell and spatial omics (2022) (3)
- Longitudinal single cell profiling of regulatory T cells identifies IL-33 as a driver of tumor immunosuppression (2019) (3)
- Abstract 4859: Development of a cancer transcriptome analysis toolkit: identification of gene fusions in chronic lymphocytic leukemia (2015) (2)
- A cell-free antibody engineering platform rapidly generates SARS-CoV-2 neutralizing antibodies (2020) (2)
- The chromatin landscape of Th17 cells reveals mechanisms of diversification of regulatory and pro-inflammatory states (2022) (2)
- Intrinsic and extrinsic regulation of human fetal bone marrow haematopoiesis and perturbations in Down syndrome (2021) (2)
- Whole Genome Sequencing Identifies Functional Mutations In the Wnt Pathway In CLL (2010) (2)
- Human Dendritic Cells Common Genetic Variants Modulate Pathogen-Sensing Responses in (2014) (2)
- In silico tissue generation and power analysis for spatial omics (2023) (2)
- Publisher Correction: Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes (2021) (2)
- Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer (2021) (2)
- Author Correction: Comprehensive comparative analysis of 5′-end RNA-sequencing methods (2018) (2)
- Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features (2020) (2)
- The BRAIN Initiative Cell Census Network Data Ecosystem: A User’s Guide (2022) (2)
- Abstract A24: Using single-cell RNA-seq approaches to decipher heterogeneity in autochthonous mouse models of small cell lung cancer (2018) (2)
- Spatial host-microbiome sequencing (2022) (2)
- Abstract 993: Whole exome sequencing of CTCs as a window into metastatic cancer (2014) (2)
- ECLIPSER: identifying causal cell types and genes for complex traits through single cell enrichment of e/sQTL-mapped genes in GWAS loci (2021) (2)
- Regulatory network controlling tumor-promoting inflammation in human cancers (2018) (2)
- Human Developmental Cell Atlas: milestones achieved and the roadmap ahead (2020) (2)
- High-resolution mapping reveals a conserved , widespread , dynamic meiotically regulated mRNA methylation program (2014) (2)
- An endogenous glucocorticoid-cytokine signaling circuit promotes CD8+ T cell dysfunction in the tumor microenvironment (2019) (2)
- Shuffle-Seq: En masse combinatorial encoding for n-way genetic interaction screens (2019) (2)
- Single-cell Genomics using Droplet-based Microfluidics (2014) (2)
- Tocilizumab treatment leads to early resolution of lymphopenia and myeloid dysregulation in patients hospitalized with COVID-19 (2023) (2)
- GWAS of stool frequency reveals genes, pathways, and cell types relevant to human gastrointestinal motility and irritable bowel syndrome (2020) (2)
- Abstract AP19: SINGLE–CELL RNA–SEQUENCING OF PATIENT–DERIVED OVARIAN CANCER CELLS AND PATIENT–DERIVED XENOGRAFT MODELS (2017) (1)
- Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics (2021) (1)
- YMAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens (2014) (1)
- Disentangling shared and group-specific variations in single-cell transcriptomics data with multiGroupVI (2022) (1)
- Single cell RNA-Seq of hematopoietic stem cells reveals a cell cycle-dependent interplay between aging and differentiation (2014) (1)
- Comparative analysis of mycobacterium and related actinomycetes yields insight into the evolution of mycobacterium tuberculosis pathogenesis (2012) (1)
- Abstract 3037: Dissecting treatment resistance in patients with ovarian cancer and PDX-models using single-cell RNA-sequencing (2017) (1)
- Hematopoiesis at single cell resolution spanning human development and maturation (2021) (1)
- Risk Alleles Identified in Genome-Wide Association Studies Are Associated with Expression Quantitative Trait Loci in Chronic Lymphocytic Leukemia. (2012) (1)
- A unified web platform for network-based analyses of genomic data (2017) (1)
- Author response: Regulation of X-linked gene expression during early mouse development by Rlim (2016) (1)
- Temporal single cell atlas of non-neuronal retinal cells reveals dynamic, coordinated multicellular responses to central nervous system injury (2022) (1)
- Single cell RNA-seq by mostly-natural sequencing by synthesis (2022) (1)
- Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types (2022) (1)
- Abstracts of Presentations at the 18th Conference of the Entomological Society of Israel (2001) (1)
- Large Intergenic Non‐Coding RNAs in Chromatin, Cancer and Stem Cells (2011) (1)
- Parental-fetal interplay of immune genes leads to intrauterine growth restriction (2021) (1)
- Single-cell multi-omics reveals dynamics of purifying selection of pathogenic mitochondrial DNA across human immune cells (2022) (1)
- A human liver cell-based system modeling a clinical prognostic liver signature combined with single cell RNA-seq for discovery of novel liver disease therapeutics (2020) (1)
- 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. (2016) (1)
- 1.11 Integrative Genomic Analysis Implicates PIK3CA and MYC in Chronic Lymphocytic Leukemia (2011) (1)
- Abstract 566: Neoantigens from translated unannotated open reading frames in cancer (2019) (1)
- Abstract A10: A distinct gene module for T cell dysfunction uncoupled from T cell activation and controlled by metallothioneins (2017) (1)
- Abstract PR-007: Single-nucleus and spatial transcriptomics of archival pancreatic ductal adenocarcinoma reveals multi-compartment reprogramming after neoadjuvant treatment (2020) (1)
- Emergence of division of labor in tissues through cell interactions and spatial cues (2022) (1)
- The Transcription Factor BATF Controls CD8+ T Cell Effector Differentiation (2013) (1)
- Single-nucleus RNA-seq and Spatial Transcriptomics of Archival Primary Pancreatic Ductal Adenocarcinoma Uncovers Multi-compartment Intratumoral Heterogeneity Associated with Neoadjuvant Chemoradiotherapy (2020) (1)
- Author Correction: A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types (2022) (1)
- Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors (2020) (1)
- Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma (2019) (1)
- Abstract 4380: Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-sequencing (2016) (1)
- DIPG-21. ELECTRICAL INTEGRATION OF GLIOMA INTO NEURAL CIRCUITRY (2019) (1)
- Inference of cell dynamics on perturbation data using adjoint sensitivity (2021) (1)
- Single-cell RNA-sequencing and -imaging of melanoma ecosystems reveals sources of resistance to immune checkpoint blockade. (2018) (1)
- reveals global properties and specific subclasses Integrative annotation of human large intergenic noncoding RNAs Material (2011) (1)
- Author Correction: Comprehensive comparative analysis of 5′-end RNA-sequencing methods (2018) (0)
- Genetic determinants of co-accessible chromatin regions in activated T cells across humans (2018) (0)
- PTPS-06SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HIGH-GRADE GLIOMA (2015) (0)
- 2017 – HUMAN HEMATOPOIETIC STEM CELL ONTOGENY ACROSS DEVELOPMENT AND MATURATION (2022) (0)
- ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS (2018) (0)
- Electrical and synaptic integration of glioma into neural circuits (2019) (0)
- HTAPP_Depletion of CD45+ cells from ovarian cancer ascites single cell suspensions for single-cell RNA-Seq v1 (2019) (0)
- Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction (2016) (0)
- TMIC-09. EXCITATORY SYNAPSES BETWEEN PRESYNAPTIC NEURONS AND POSTSYNAPTIC GLIOMA CELLS PROMOTE GLIOMA PROGRESSION (2018) (0)
- Abstract 928: Regulatory heterogeneity in glioblastoma multiforme informs novel drug target discovery (2018) (0)
- STEM-22LARGE-SCALE SINGLE-CELL RNA-seq REVEALS A DEVELOPMENTAL CELLULAR HIERARCHY IN HUMAN OLIGODENDROGLIOMA. (2015) (0)
- Leading Edge Review Impulse Control : Temporal Dynamics in Gene Transcription (0)
- Author Correction: Nuclei multiplexing with barcoded antibodies for single-nucleus genomics (2019) (0)
- HTAPP_EZ Nuclei Isolation from frozen tissue v1 (2019) (0)
- of condition-specific transcriptional modules Arboretum : Reconstruction and analysis of the evolutionary history Material Supplemental (2013) (0)
- Erratum: Deconstructing transcriptional heterogeneity in pluripotent stem cells (2015) (0)
- Abstracts of papers presented at the Sixth InternationalVerticillium Symposium Abstracts of papers presented at the Seventh Conference of the Entomological Society of Israel (1995) (0)
- Small and Large Ribosoma l Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate Graphical (2018) (0)
- Abstracts of presentations on selected topics at the XIVth international plant protection congress (IPPC) July 25–30, 1999 (2008) (0)
- The network effect: studying COVID-19 pathology with the Human Cell Atlas (2020) (0)
- DIPG-06. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES. (2017) (0)
- Abstract P5-06-02: A gene expression meta-analysis identifies microenvironment differences in cellular composition and cell-cell interactions associated with breast cancer invasion (2022) (0)
- HTAPP_Test protocol__Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using Liberase TM) v1 (0)
- Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution (2015) (0)
- Abstracts of papers presented at the 12th congress of the israeli phytopathological society (1990) (0)
- Raman2RNA: Live-cell label-free prediction of single-cell expression profiles by Raman microscopy (Conference Presentation) (2023) (0)
- HTAPP_OCT-embedded frozen tissue sectioning and mounting on Visium specialized slides v1 (2020) (0)
- A gene module driving co-inhibitory receptors expression on T cells (2017) (0)
- EPCO-35. SINGLE-CELL RNA-SEQ OF PEDIATRIC EPENDYMOMA REVEALS PROGNOSTIC IMPACT OF IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION (2020) (0)
- LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS (2019) (0)
- Abstract 5387: Novel targeted single-cell TCR sequencing method used for analysis of a T cell infiltrate from a glioblastoma patient (2018) (0)
- Cell Homeostasis The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft (2020) (0)
- Abstract PD6-03: Spatio-molecular dissection of the breast cancer metastatic microenvironment (2022) (0)
- HTAPP_Dissociation of human primary lung cancer resection to a single-cell suspension for single-cell RNA-seq v1 (2019) (0)
- Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation (2018) (0)
- Resource Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming Graphical (0)
- Transcriptional regulation of IL-10 in T helper cells (2019) (0)
- HTAPP_Processing human ovarian cancer ascites to a single-cell suspension for single-cell RNA-seq v2 (2020) (0)
- Epigenetic Changes Driven by EGFR Signaling (2011) (0)
- Cell Atlases as Roadmaps in Health and Disease. (2020) (0)
- 964 Dynamic immune landscapes during melanoma progression reveal a role for endogenous opioids in driving T cell dysfunction (2022) (0)
- Increased Dysfunction of Tumor Specific TCF-1+ CD8+ T Cells Associated with Increase in Non-Cycling TCF-1+ SlamF6- Cells Subsets Revealed by Single Cell Analysis (2020) (0)
- DIPG-03. EXCITATORY SYNAPSES BETWEEN PRESYNAPTIC NEURONS AND POSTSYNAPTIC GLIOMA CELLS PROMOTE DIPG PROGRESSION (2018) (0)
- Author Correction: A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types (2022) (0)
- HTAPP_CST- Nuclei isolation from frozen tissue v2 (2020) (0)
- Cellular network perturbations point to a new microglia‐astrocyte community accelerating Alzheimer’s disease progression (2022) (0)
- Abstract 2173: Robust estimation of mutation burden (2015) (0)
- Reconstructing regulatory circuits: lessons from immune cells (92.1) (2014) (0)
- Inference of single cell profiles from histology stains with the Single-Cell omics from Histology Analysis Framework (SCHAF) (2023) (0)
- Abstract PR08: Leveraging single-cell epigenomics to uncover regulatory programs in lung adenocarcinoma (2020) (0)
- Abstract 94: Multi-compartment reprogramming and spatially-resolved interactions in frozen pancreatic cancer with and without neoadjuvant chemotherapy and radiotherapy at single-cell resolution (2021) (0)
- HTAPP_Test protocol_Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using papain and ACK) v1 (2021) (0)
- Abstract 639: Rapidly evaluating cancer dependencies by label-free imaging of zero-passage primary cells (2022) (0)
- Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq (2020) (0)
- Abstract LB550: AI predicts risk of pancreatic cancer from disease trajectories using real-world electronic health records (EHRs) from Denmark and the USA (2022) (0)
- Filling missing components in yeast metabolic pathways using heterogeneous data (0)
- HTAPP_Dissociation of human ovarian cancer resection to a single-cell suspension for single-cell RNA-seq v1 (2019) (0)
- Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma (2020) (0)
- HTAPP_Smart-Seq2_Modified SS2-M protocol for frozen glioma and sarcoma samples v1 (2019) (0)
- Probabilistic reconstruction of cellular differentiation trees from single-cell RNA-seq data (2017) (0)
- Abstract SY45-04: Development of therapeutic strategies by resolving the tumor ecosystem (2019) (0)
- Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma (2019) (0)
- MAUDE: inferring expression changes in sorting-based CRISPR screens (2020) (0)
- Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade (2022) (0)
- Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods (2019) (0)
- Abstract A22: Molecular subtypes and resistance programs in pancreatic ductal adenocarcinoma elucidated with single-nucleus RNA-seq (2019) (0)
- Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis (2020) (0)
- GENT-16. REDEFINING THE CELLULAR ARCHITECTURE OF ADULT AND PEDIATRIC GLIOBLASTOMAS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES (2016) (0)
- Single-cell RNA-seq identifies the neuropeptide NMU as a novel regulator of ILC2 function (2018) (0)
- Author Correction: Massively parallel phenotyping of coding variants in cancer with Perturb-seq (2022) (0)
- Compressed Perturb-seq: highly efficient screens for regulatory circuits using random composite perturbations (2023) (0)
- Glucocorticoid signaling regulates CD8+T cell responses in cancer (2019) (0)
- Abstract B13: Integrative genomic and transcriptomic analysis of 775 human cancer cell lines reveals tumor-derived immune programs and their regulators (2017) (0)
- HTAPP_Dissociation of primary neuroblastoma core needle biopsy to a single-cell suspension for single-cell RNA-seq (using papain, density gradient, and optionally ACK) v1 (2020) (0)
- Disease-associated astrocytes in Alzheimer’s disease and aging (2020) (0)
- Abstract IA34: Targeting cellular heterogeneity in lung adenocarcinoma (2018) (0)
- Comprehensive comparative analysis of 5′-end RNA-sequencing methods (2018) (0)
- Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages the Immunological (2012) (0)
- HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS. (2016) (0)
- Joint Xena-Trinity-Cistrome-Cravat/MuPIT Collaboration (2014) (0)
- OTME-7. Cancer - immune cell interactions drive transitions to mesenchymal-like state in glioblastoma (2021) (0)
- Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (0)
- Abstract 3647: Single cell RNA sequencing reveals mitogenic and progenitor gene programs inBRAF-rearranged pilocytic astrocytomas (2019) (0)
- Abstract B085: Combining transcriptomic profiling and genome engineering to dissect regulation of tumor immunology (2016) (0)
- 062 Human melanoma TILs share phenotypic and transcriptional properties with tissue resident memory T cells (2017) (0)
- Cell Atlas of The Human Fovea and Peripheral Retina (2020) (0)
- Abstract A052: Systematic dissection of transcriptional states in pancreatic cancer (2022) (0)
- Author Correction: Deciphering eukaryotic gene-regulatory logic with 100 million random promoters (2020) (0)
- 065 Highly conserved tissue immune signatures are co-opted in cancer (2017) (0)
- HTAPP_Dissociation of human ovarian cancer resection to a single-cell suspension for single-cell RNA-seq v2 (2020) (0)
- HTAPP_Smart-Seq2 Version 6.1 (SS2-M for cells) v1 (2019) (0)
- Hematopoietic Stem Cells Respond Heterogeneously to Inflammatory Signals in an Age-Dependent Manner (2016) (0)
- Endogenous glucocorticoid signaling regulates effector differentiation and development of dysfunction in CD8 + T cells in the tumor microenvironment (2020) (0)
- ISMB 2003 BioPathways SIG and 5th BioPathways Meeting (2003) (0)
- Trinity CTAT: a community resource for de novo and reference-based RNA-Seq analysis (2016) (0)
- Abstract PR05: Loss of PRC2 or KMT2D-COMPASS generates two quasi-mesenchymal cell states with distinct metastatic abilities (2020) (0)
- HTAPP_Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using papain, density gradient, and optionally ACK) v1 (2021) (0)
- HTAPP_TST- Nuclei isolation from frozen tissue v1 (2019) (0)
- HTAPP_Smart-Seq2 Version 6.1 (SS2-M for nuclei) v1 (2019) (0)
- Modularity, evolution and regulation in bionetworks (2005) (0)
- Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility. (2023) (0)
- EPEN-21. IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION IN PEDIATRIC EPENDYMOMA REVEALED BY SINGLE-CELL RNA-SEQ (2020) (0)
- Anti-Tumor TCF1+ CD8 T Cells are Functionally Diverse and Evolve During Tumorigenesis and Progression (2020) (0)
- TAMI-12. CANCER-IMMUNE CELL INTERACTIONS DRIVE TRANSITIONS TO MESENCHYMAL-LIKE STATES IN GLIOBLASTOMA (2021) (0)
- Speaker-specific terms and resources (0)
- HTAPP_NST- Nuclei isolation from frozen tissue v1 (2019) (0)
- Abstract 131: Remodeling of stromal-epithelial interactions in breast cancer progression as inferred from regional and single-cell gene expression analysis (2021) (0)
- Genome-wide identification and characterization of replication origins by deep sequencing (2012) (0)
- ISMB 2003 BioPathways SIG and 5 th BioPathways Meeting ISMB ’ 03 , Brisbane , Australia , 27 – 28 June 2003 (2014) (0)
- Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq (2023) (0)
- Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding (2022) (0)
- CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours (2022) (0)
- Abstract A082: Single-cell RNA-sequencing of metastatic melanoma identifies a cancer cell-intrinsic program associated with immune checkpoint inhibitor resistance (2019) (0)
- 775 Hyperactivation of sympathetic nerves drives melanocyte stem cell depletion (2020) (0)
- Cell-type specific developmental defects in PTEN-mutant cortical organoids converge on abnormal circuit activity (2022) (0)
- HTAPP_Test protocol__Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using collagenase 4 and Liberase TM) v1 (0)
- Transcriptional insights into the CD8[superscript +] T cell response to infection and memory T cell formation (2013) (0)
- Resource Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina Graphical (2019) (0)
- Loss of IFNgR1 signaling glioblastoma drives resistance to CAR T cell binding avidity and cytotoxicity due to lower downstream expression of ICAM-1 (2022) (0)
- Abstract 2101: Targeting the root of cancer persister cells using an expressed barcode library (2019) (0)
- Abstract 5331: GenomeSpace: An environment for frictionless bioinformatics (2014) (0)
- HTAPP_Dissociation of human primary colorectal cancer resection specimens into single cell suspension for single cell RNA-seq v2 (2021) (0)
- HTAPP - Multi-assay sectioning of OCT-embedded samples for spatial profiling v1 (2020) (0)
- Decoding human fetal liver haematopoiesis (2019) (0)
- 087 Molecular and cellular mechanisms of tolerogenic signature induction in CD4+ T cells by apoptotic cells (2019) (0)
- P4-254 IDENTIFICATION OF INFLAMMATORY PROCESSES SURROUNDING AMYLOID-b DEPOSITS INTHERETINAOFMCIANDAD PATIENTS (0)
- SlideCNA: Spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data (2022) (0)
- 221 CRISPR screen identifies loss of IFNγR signaling and downstream adhesion as a resistance mechanism to CAR T-cell cytotoxicity in solid but not liquid tumors (2021) (0)
- Cell-specific metabolic models reveal novel metabolic regulators of Th17 pathogenicity: from single-cell RNA-Seq to actionable metabolic targets (2018) (0)
- Metabolic Network Analysis Demystified (2011) (0)
- Author response: The evolution of drug resistance in clinical isolates of Candida albicans (2014) (0)
- DroNc-seq step-by-step (2017) (0)
- OTME-8. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis (2021) (0)
- Single-cell temporal dynamics reveals the relative contributions of transcription and degradation to cell-type specific gene expression in zebrafish embryos (2023) (0)
- HTAPP_Sorting nuclei into 96-well plates for Smart-Seq2 v1 (2019) (0)
- Supporting Online Material for Comparative Functional Genomics of the Fission Yeasts (2011) (0)
- PDTM-32. RESOLVING MEDULLOBLASTOMA CELLULAR ARCHITECTURE BY SINGLE-CELL GENOMICS (2019) (0)
- during zebrafish embryogenesis Systematic identification of long noncoding RNAs expressed Material (2012) (0)
- TMIC-18. ELECTRICAL CIRCUIT INTEGRATION OF GLIOMA THROUGH NEURON-GLIOMA SYNAPSES AND POTASSIUM CURRENTS (2019) (0)
- EPCO-14. DECIPHERING DIFFERENTIATION HIERARCHIES, HERITABILITY AND PLASTICITY IN HUMAN GLIOMAS VIA SINGLE-CELL MULTI-OMICS (2020) (0)
- BRIDGE- HTAPP_Depletion of CD45+ cells from ovarian cancer ascites single cell suspensions for single-cell RNA-Seq v1 (2019) (0)
- Abstract 1511: A highly plastic cell state emerges during lung adenocarcinoma evolution (2020) (0)
- Author Correction: Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias (2021) (0)
- LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING (2018) (0)
- HTAPP_Dissociation of human metastatic breast cancer core needle biopsy to a single-cell suspension for single-cell RNA-seq v1 (2019) (0)
- HTAPP_Dissociation of human primary lung cancer resection to a single-cell suspension for single-cell RNA-seq v2 (2020) (0)
- Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells (2020) (0)
- Toward a Whole Cell Model of Mycoplasma Genitalium (2011) (0)
- HTAPP_Depletion of CD45+ cells from ovarian cancer ascites single cell suspensions for single-cell RNA-Seq v2 (2020) (0)
- Combinatorics of Cis‐Regulatory Element Evolution in Stress Response Modules of Ascomycete Yeasts (2012) (0)
- HTAPP_Test protocol_Dissociation of primary neuroblastoma core needle biopsy to a single-cell suspension for single-cell RNA-seq (using collagenase 4) v1 (0)
- database mining and microarray analysis Identification of endothelial cell genes by combined (2015) (0)
- Abstract 1431: In vivo CRISPR/Cas9 screen of adoptively transferred T cells reveals novel mediators of T cell exhaustion and immunosuppression (2019) (0)
- HTAPP_Dissociation of human primary colorectal cancer resection specimens into single cell suspension for single cell RNA-seq v1 (2019) (0)
- TFR-derived Fibrinogen-like Protein 2 regulates production of autoantibodies and induction of systemic autoimmunity (2020) (0)
- HTAPP_NST- Nuclei isolation from frozen tissue v2 (2020) (0)
- The Organoid Cell Atlas (2020) (0)
- Abstract 2506:Smarca4inactivation promotes lineage-specific transformation and early metastatic features in the lung (2021) (0)
- HTAPP_OCT embedding of snap frozen tumor tissue v1 (2019) (0)
- Report daptation and Dobzhansky-Muller Interaction in Experimental Yeast Populations (2010) (0)
- Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes (2021) (0)
- Abstract 4320: Ovarian cancer persister cells are characterized by enhanced ER stress gene expression correlating with poor survival (2020) (0)
- 046 Dynamic regulatory network controlling Tr1 cell development in epithelial tissue inflammation (2017) (0)
- Induction and transcriptional regulation of the co-inhibitory gene module in T cells (2018) (0)
- Spatiotemporal functional genomics uncovers cell circuits triggering liver disease biology of hepatitis C virus infection (2017) (0)
- Temporal Tracking of Micr oglia Activation in Neurodegeneration at Single-Cell Resolution Graphical (2017) (0)
- snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis (2020) (0)
- Remodeling of human colon plasma cell repertoire in ulcerative colitis (2022) (0)
- Publisher Correction: Voices of biotech leaders (2021) (0)
- HTAPP_Dissociation of human metastatic breast cancer lymph node excision biopsy to a single-cell suspension for single-cell RNA-seq v1 (2019) (0)
- Abstract PO-019: Deciphering differentiation hierarchies, heritability and plasticity in human gliomas via single-cell multi-omics (2020) (0)
- Characterization of Mammary Cells Co‐expressing Separate Lineage Markers (2020) (0)
- Developmental Cell Perspective The Pediatric Cell Atlas : Defining the Growth Phase of Human Development at Single-Cell Resolution (0)
- Generation of a mouse model of extrathymically-derived regulatory T cells in type 1 diabetes (2018) (0)
- Exact Identification of Topologically Essential Interactions in the Networks Derived from Perturbation Experiments (2011) (0)
- Induction of a colitogenic phenotype in Th1 cells depends on IL-23R signaling (2021) (0)
- Evaluation and optimization of sequence-based gene regulatory deep learning models (2023) (0)
- Implementation of single-cell genomics as a translational tool in patients with metastatic melanoma. (2016) (0)
- CeVICA selection protocol v1 (2021) (0)
- Single Cell Analysis Elucidates the Maturation of Human Stem and Progenitor Cell Function from Fetal through Adult Hematopoiesis (2021) (0)
- High-definition spatial transcriptomics for in situ tissue profiling (2019) (0)
- Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies (2018) (0)
- Abstract GS6-05: A joint atlas of single-cell and bulk RNA-seq in metastatic breast cancer allows inference of oncogenic and drug-resistant transcriptional programs in malignant cells and the tumor microenvironment (2020) (0)
- Inbred Mouse Strains Expression in Primary Immunocytes across Variation and Genetic Control of Gene (2014) (0)
- Single-cell clonotype tracing of tissue Th17 cells during CNS autoimmunity reveals the conversion of intestinal homeostatic cells to pathogenic cells (2021) (0)
- Abstract 5722: Acquired stemness by luminal cells (2020) (0)
- HTAPP_Samples for spatial assays: selection criteria from H&E review v1 (2020) (0)
- Genome-wide reconstructions of the evolution of genes and regulatory elements in ascomycota fungi (2008) (0)
- MetaMerge: scaling up genome-scale metabolic reconstructions with application to Mycobacterium tuberculosis (2012) (0)
- Introduction to the Trinity Cancer Transcriptome Analysis Toolkit (2015) (0)
- Voices of biotech leaders (2021) (0)
- A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease (2018) (0)
- Abstract GS2-02: Acquired activating mutations in RTKs confer endocrine resistance in ER+ metastatic breast cancer through ER-reprogramming, MAPK signaling, and an induced stem-like cell state (2020) (0)
- A single-cell atlas of human and mouse white adipose tissue (2022) (0)
- Inherent Limitations of Parameter Estimation of a Tempo-Spatial Field Using an Array of Heterogeneous Sensors (2021) (0)
- Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr 5 and Lgr 6 Graphical Abstract Highlights (2017) (0)
- Sequencing the genome of Candida albicans as it evolves in a patient reveals the genetic changes that allow the yeast to adapt to its environment. (2015) (0)
- Abstracts of Papers Presented at the Japan-Israel Workshop on Novel Approaches for Controlling Insect Pests and Plant Diseases Binational Plant Protection Cooperation (1997) (0)
- Abstract 5266: Fast and accurate fusion transcript detection using the Trinity Cancer Transcriptome Analysis Toolkit (2016) (0)
- Critical role of the transcription factors IRF 1 and BATF in preparing the chromatin landscape during Type 1 regulatory cell differentiation (2018) (0)
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (0)
- Author Correction: Molecular logic of cellular diversification in the mouse cerebral cortex (2021) (0)
- Single-nucleus RNA-seq of frozen archival primary pancreatic ductal adenocarcinoma uncovers multi-compartment intratumoral heterogeneity associated with neoadjuvant treatment. (2020) (0)
- HTAPP_Designing gene panels for neuroblastoma targeted spatial transcriptomics assays v1 (2021) (0)
- Abstract SY12-04: Multicellular spatial community featuring a novel neuronal-like malignant phenotype is enriched in pancreatic cancer after neoadjuvant chemotherapy and radiotherapy (2022) (0)
- Abstract IA4: Linking RNA to human health and disease (2012) (0)
- Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens. (2023) (0)
- HTAPP_Designing gene panels for metastatic breast cancer targeted spatial transcriptomics assays v1 (2021) (0)
- Conservation and divergence in modules of the transcriptional programs of the human and mouse immune systems [preprint] (2020) (0)
- HTAPP_Depletion of CD45+ cells from single-cell suspension for single-cell RNA-seq v1 (2020) (0)
- EPCO-07. HYBRID NEURO-GLIAL CELLULAR ARCHITECTURE IN HIGH-GRADE GLIOMA DRIVEN BY H3-G34R MUTATION (2021) (0)
- HTAPP_Test protocol__Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using collagenase 4) v1 (0)
- Conservation and divergence in modules of the transcriptional programs of the human and mouse immune systems (2018) (0)
- Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening (2022) (0)
- Conservation and divergence in modules of the transcriptional programs of the human and mouse immune systems (2018) (0)
- HTAPP_Dissociation of human metastatic breast cancer core needle biopsy to a single-cell suspension for single-cell RNA-seq v2 (2020) (0)
- Deciphering eukaryotic gene-regulatory logic with 100 million random promoters (2019) (0)
- Abstract PR-006: Integrative genomic characterization of therapeutic targets for pancreatic cancer (2021) (0)
- Author Correction: Nuclei multiplexing with barcoded antibodies for single-nucleus genomics (2020) (0)
- A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients (2022) (0)
- Abstract 3301: Using a novel single-cell lineage-tracing technique to uncover the mechanisms driving nongenetic cancer relapse (2018) (0)
- StochasticCalculus - a Tutorial (2012) (0)
- HTAPP_Processing human ovarian cancer ascites to a single-cell suspension for single-cell RNA-seq v1 (2019) (0)
- Remodeling of colon plasma cell repertoire within ulcerative colitis patients. (2023) (0)
- Author Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse (2022) (0)
- HTAPP_CST- Nuclei isolation from frozen tissue v1 (2019) (0)
- Miniaturizing 3D assay for high-throughput drug and genetic screens for small patient-derived tumor samples (Conference Presentation) (2017) (0)
- HTAPP_ Sorting nuclei into 96-well plates for Smart-Seq2 v1 (2019) (0)
- Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease (2023) (0)
- HTAPP_Enrichment of EpCAM+ cells from single-cell suspension for single-cell RNA-seq v1 (0)
- 641 Spatially organized multicellular immune hubs in MMRd and MMRp colorectal cancer (2021) (0)
- BRNI : Modular analysis of transcriptional regulatory programs Citation (2009) (0)
- Abstract SY15-04: Systematic reconstruction of regulatory networks in mammalian cells: Lessons from the pathogen response (2010) (0)
- Comprehensive Identifica tion and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA- Seq (2020) (0)
- Y[subscript MAP]: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens (2014) (0)
- HTAPP_Dissociation of human metastatic breast cancer lymph node excision biopsy to a single-cell suspension for single-cell RNA-seq (using Collagenase 4 and Dispase II) v1 (2021) (0)
- Functional analyses and single cell immunoprofiling uncover sex-specific differences in SARS-CoV2 immune memory development (2022) (0)
- 191 EZH2 and GATA3 Play Opposing Roles in Controlling the Differentiation State of Basal-like Breast Cancer Cells (2012) (0)
- Comparative cellular analysis of motor cortex in human, marmoset and mouse (2021) (0)
- Towfique Raj Risk Alleles in Leukocytes Polarization of the Effects of Autoimmune and Neurodegenerative (2014) (0)
- A revised airway epithelial hierarchy includes CFTR-expressing ionocytes (2018) (0)
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