Axel M. Gressner

Q: What Schools Are Affiliated With Axel M. Gressner

Axel M. Gressner is affiliated with the following schools: University of Marburg, RWTH Aachen University

Axel M. Gressner's AcademicInfluence.com Rankings

Axel M. Gressner

Biology

#7083

World Rank

#9943

Historical Rank

Endocrinology

#68

World Rank

#79

Historical Rank

biology Degrees

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Biology

Axel M. Gressner's Degrees

PhD Biochemistry Stanford University
Doctorate Internal Medicine Stanford University

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Axel M. Gressner's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. (2004) (1025)
Roles of TGF-beta in hepatic fibrosis. (2002) (846)
Patients with acute on chronic liver failure display "sepsis-like" immune paralysis. (2005) (479)
Ito cells are liver-resident antigen-presenting cells for activating T cell responses. (2007) (403)
Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats. (2003) (363)
Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans (2005) (262)
Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases (2008) (261)
The synthesis of proteoglycans in fat‐storing cells of rat liver (1987) (250)
The phosphorylation of liver ribosomal proteins in vivo. Evidence that only a single small subunit protein (S6) is phosphorylated. (1974) (250)
Molecular mechanisms of liver fibrogenesis--a homage to the role of activated fat-storing cells. (1995) (237)
Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblastlike cells. A potential mechanism of self perpetuation in liver fibrogenesis. (1992) (233)
Modulation of transforming growth factor β response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts (2000) (224)
Tissue inhibitor of metalloproteinase-1 and -2 RNA expression in rat and human liver fibrosis. (1997) (219)
Enhanced release of cytokines, interleukin-2 receptors, and neopterin after long-distance running. (1992) (210)
Biomarkers of liver fibrosis: clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests. (2007) (210)
The cell biology of liver fibrogenesis – an imbalance of proliferation, growth arrest and apoptosis of myofibroblasts (1998) (204)
Pro-fibrogenic potential of PDGF-D in liver fibrosis. (2007) (180)
Transforming growth factor β signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts (2001) (169)
Isolation and culture of hepatic stellate cells. (2005) (155)
Saliva collection method affects predictability of serum cortisol. (2007) (154)
Measurement of proteins with the Behring Nephelometer. A multicentre evaluation. (1989) (151)
Cytokines and cellular crosstalk involved in the activation of fat-storing cells. (1995) (150)
Up‐regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts (2001) (147)
Participation of Smad2, Smad3, and Smad4 in transforming growth factor beta (TGF-beta)-induced activation of Smad7. THE TGF-beta response element of the promoter requires functional Smad binding element and E-box sequences for transcriptional regulation. (2000) (147)
Dominant-negative soluble PDGF-β receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis (2004) (143)
Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes. (2007) (143)
Tumor‐dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis (1997) (142)
Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options (2007) (142)
Inhibition of hepatic fibrogenesis by matrix metalloproteinase‐9 mutants in mice (2006) (140)
Pharmacological aspects of pentoxifylline with emphasis on its inhibitory actions on hepatic fibrogenesis. (1997) (139)
Id1 is a critical mediator in TGF‐β–induced transdifferentiation of rat hepatic stellate cells (2006) (137)
Gc-globulin: roles in response to injury. (2006) (134)
Immunological measurement of transforming growth factor-beta 1 (TGF-beta1) in blood; assay development and comparison. (1997) (133)
Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: a key event in hepatic fibrogenesis. (1996) (131)
Prevalence of pituitary deficiency in patients after aneurysmal subarachnoid hemorrhage. (2004) (125)
Association of polymorphisms of the transforming growth factor-beta1 gene with the rate of progression of HCV-induced liver fibrosis. (2002) (124)
Tumor necrosis factor alpha (TNFα) and transforming growth factor β1 (TGFβ1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts (1993) (121)
IFN-γ abrogates profibrogenic TGF-β signaling in liver by targeting expression of inhibitory and receptor Smads (2007) (119)
Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. (2008) (115)
National Committee for Clinical Laboratory Standards (2019) (112)
Cellular sources of noncollagenous matrix proteins: role of fat-storing cells in fibrogenesis. (1990) (109)
Zinc supplementation in the elderly reduces spontaneous inflammatory cytokine release and restores T cell functions. (2008) (108)
Endoglin Differentially Modulates Antagonistic Transforming Growth Factor-β1 and BMP-7 Signaling* (2007) (106)
Serum laminin and hyaluronan in liver cirrhosis: markers of progression with high prognostic value. (1996) (102)
Transformation‐dependent susceptibility of rat hepatic stellate cells to apoptosis induced by soluble fas ligand (1998) (102)
Lower cardiac troponin T and I results in heparin-plasma than in serum. (2000) (99)
Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury (2008) (97)
Abrogation of Transforming Growth Factor-β Signaling by SMAD7 Inhibits Collagen Gel Contraction of Human Dermal Fibroblasts* (2005) (96)
Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells. (1997) (95)
Adenoviral expression of a transforming growth factor-β1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats (2003) (94)
Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function? (2007) (94)
TGF-β-mediated hepatocellular apoptosis by rat and human hepatoma cells and primary rat hepatocytes (1997) (92)
Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis. (2004) (90)
Resistin Serum Levels Are Associated with Insulin Resistance, Disease Severity, Clinical Complications, and Prognosis in Patients with Chronic Liver Diseases (2006) (90)
Evaluation of a new, rapid bedside test for quantitative determination of B-type natriuretic peptide. (2001) (89)
Expression pattern of fibroblast growth factors (FGFs), their receptors and antagonists in primary endothelial cells and vascular smooth muscle cells (2005) (88)
The stimulation of the phosphorylation of ribosomal protein S6 by cycloheximide and puromycin. (1974) (87)
Modulation of hepatic lipocyte proteoglycan synthesis and proliferation by Kupffer cell-derived transforming growth factors type β1 and type α (1990) (85)
Changing the pathogenetic roadmap of liver fibrosis? Where did it start; where will it go? (2008) (84)
Haptoglobin (2019) (82)
Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors α and β in activated rat hepatic stellate cells (HSC) (2005) (82)
Biglycan and decorin gene expression in normal and fibrotic rat liver: Cellular localization and regulatory factors (1992) (82)
Y-box Protein-1 Is the Crucial Mediator of Antifibrotic Interferon-γ Effects* (2006) (81)
BMP-7 as antagonist of organ fibrosis. (2009) (81)
Procalcitonin serum levels after out-of-hospital cardiac arrest. (2003) (80)
IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads. (2007) (78)
Transforming growth factor-β1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection (2005) (77)
Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis. (2006) (76)
(Latent) transforming growth factor β in liver parenchymal cells, its injury‐dependent release, and paracrine effects on rat hepatic stellate cells (1998) (76)
Proliferation of fat-storing cells is stimulated by secretions of Kupffer cells from normal and injured liver. (1988) (75)
Thrombospondin 1 acts as a strong promoter of transforming growth factor β effects via two distinct mechanisms in hepatic stellate cells (2005) (74)
Liver fat storing cell proliferation is stimulated by epidermal growth factor/transforming growth factor alpha and inhibited by transforming growth factor beta. (1989) (73)
Hyperglycemia at admission to the intensive care unit is associated with elevated serum concentrations of interleukin-6 and reduced ex vivo secretion of tumor necrosis factor-&agr;* (2004) (73)
Perisinusoidal lipocytes and fibrogenesis. (1994) (72)
Induction of rat liver parenchymal cell apoptosis by hepatic myofibroblasts via transforming growth factor β (1996) (72)
Hyaluronic acid synthesis and secretion by rat liver fat storing cells (perisinusoidal lipocytes) in culture. (1988) (71)
Expression of Smads during in vitro transdifferentiation of hepatic stellate cells to myofibroblasts. (2001) (70)
Cellular distribution and function of soluble guanylyl cyclase in rat kidney and liver. (2001) (70)
LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1. (2001) (69)
Rapid genotyping of hemochromatosis gene mutations on the LightCycler with fluorescent hybridization probes. (1999) (69)
Liver fibrosis: perspectives in pathobiochemical research and clinical outlook. (1991) (69)
Hepatic stellate cells display a functional vascular smooth muscle cell phenotype in a three-dimensional co-culture model with endothelial cells. (2008) (68)
Influence of glucagon and cyclic adenosine 3':5'-monophosphate on the phosphorylation of rat liver ribosomal protein S6. (1976) (68)
Elevation of Nepsilon-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis. (2006) (67)
The response of rat liver perisinusoidal lipocytes to polypeptide growth regulator changes with their transdifferentiation into myofibroblast-like cells in culture. (1993) (65)
Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells. (2002) (65)
Molecular dissection of the mitogenic effect of hepatocytes on cultured hepatic stellate cells (1995) (64)
Decreased Plasminogen Activator Inhibitor and Tissue Metalloproteinase Inhibitor Expression May Promote Increased Metalloproteinase Activity with Increasing Duration of Human Atrial Fibrillation (2007) (64)
Identification and partial characterization of a hepatocyte‐derived factor promoting proliferation of cultured fat‐storing cells (parasinusoidal lipocytes) (1992) (63)
Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C (2004) (63)
Activation of TGF-β within cultured hepatocytes and in liver injury leads to intracrine signaling with expression of connective tissue growth factor (2008) (61)
Logistic-regression model for assessing portal hypertension by measuring hyaluronic acid (hyaluronan) and laminin in serum. (1991) (61)
Transforming growth factor β (TGF‐β) expression in isolated and cultured rat hepatocytes (1996) (60)
Validation by isoelectric focusing of the anion-exchange isotransferrin fractionation step involved in determination of carbohydrate-deficient transferrin by the CDTect assay. (1998) (60)
Elevated apoptosis-associated cytokeratin 18 fragments (CK18Asp386) in serum of patients with chronic liver diseases indicate hepatic and biliary inflammation. (2007) (59)
Non-invasive biomarkers for monitoring the fibrogenic process in liver: a short survey. (2009) (59)
Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation. (2006) (59)
Insulin resistance in liver cirrhosis is not associated with circulating retinol-binding protein 4. (2007) (59)
Kupffer cell-mediated induction of synthesis and secretion of proteoglycans by rat liver fat-storing cells in culture. (1987) (59)
The Role of Thrombocytes in Liver Fibrogenesis: Effects of Platelet Lysate and Thrombocyte-Derived Growth Factors on the Mitogenic Activity and Glycosaminoglycan Synthesis of Cultured Rat Liver Fat Storing Cells (1989) (58)
Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor β actions in hepatocytes—But without modulating bone morphogenetic protein 7 signaling (2009) (57)
N-acetyl-L-cysteine suppresses TGF-beta signaling at distinct molecular steps: the biochemical and biological efficacy of a multifunctional, antifibrotic drug. (2005) (57)
Comparison of Sulphated Glycosaminoglycan and Hyaluronate Synthesis and Secretion in Cultured Hepatocytes, Fat Storing Cells, and Kupffer Cells (1989) (56)
Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors alpha and beta in activated rat hepatic stellate cells (HSC). (2005) (56)
Expression and matrix deposition of latent transforming growth factor β binding proteins in normal and fibrotic rat liver and transdifferentiating hepatic stellate cells in culture (2001) (56)
Transforming growth factor beta signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. TGFbeta signal transduction during transdifferentiation of hepatic stellate cells. (2001) (55)
Regulation of hyaluronate synthesis in rat liver fat storing cell cultures by Kupffer cells. (1988) (55)
Comparison of β2-Transferrin and β-Trace Protein for Detection of Cerebrospinal Fluid in Nasal and Ear Fluids (2004) (54)
Isoforms and splice variant of transforming growth factor beta-binding protein in rat hepatic stellate cells. (1998) (54)
Identification of Endoglin in Rat Hepatic Stellate Cells (2005) (54)
Serum concentrations of laminin and aminoterminal propeptide of type III procollagen in relation to the portal venous pressure of fibrotic liver diseases. (1986) (54)
Transforming growth factors (TGFα and TGFβH) stimulate chondroitin sulfate and hyaluronate synthesis in cultured rat liver fat storing cells (1989) (53)
Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects. (2006) (53)
Efficacy of serum laminin measurement for diagnosis of fibrotic liver diseases. (1988) (52)
Molecular and functional aspects of latent transforming growth factor-β binding protein: just a masking protein? (1999) (52)
Increased serum concentration of carbohydrate-deficient transferrin in patients with combined pancreas and kidney transplantation. (1997) (52)
Effect of experimental diabetes and insulin on phosphorylation of rat liver ribosomal protein S6 (1976) (51)
Synergism between hepatocytes and Kupffer cells in the activation of fat storing cells (perisinusoidal lipocytes). (1993) (51)
Differential expression of monocyte chemotactic protein-1 (MCP-1) in transforming rat hepatic stellate cells. (1999) (50)
Cellular communications and cell-matrix interactions in the pathogenesis of fibroproliferative diseases: liver fibrosis as a paradigm. (1994) (49)
Regulation of proteoglycan expression in fibrotic liver and cultured fat-storing cells. (1994) (48)
The biosynthesis of glycosaminoglycans in normal rat liver and in response to experimental hepatic injury. (1977) (46)
Glucocorticoids decrease the bioavailability of TGF-β which leads to a reduced TGF-β signaling in hepatic stellate cells (2004) (46)
Attenuation of TGF-beta-induced apoptosis in primary cultures of hepatocytes by calpain inhibitors. (1997) (46)
Transformation-dependent calcium influx by voltage-operated calcium channels in stellate cells of rat liver. (1999) (46)
Elevation of endoglin (CD105) concentrations in serum of patients with liver cirrhosis and carcinoma (2007) (44)
Comparative evaluation of gene delivery devices in primary cultures of rat hepatic stellate cells and rat myofibroblasts (2000) (43)
Analysis of the expression pattern of the latent transforming growth factor β binding protein isoforms in normal and diseased human liver reveals a new splice variant missing the proteinase‐sensitive hinge region (1998) (43)
Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor β1 in Cultured Hepatic Stellate Cells. (1997) (42)
Modulation of hepatic lipocyte proteoglycan synthesis and proliferation by Kupffer cell-derived transforming growth factors type beta 1 and type alpha. (1990) (42)
Subcellular localization of (latent) transforming growth factor β and the latent TGF‐β binding protein in rat hepatocytes and hepatic stellate cells (1998) (41)
Expression of different isoforms of TGF-β and the latent TGF-β binding protein (LTBP) by rat Kupffer cells (1998) (41)
Genomic locus and promoter region of rat Smad7, an important antagonist of TGFβ signaling (2000) (41)
Characterization of Insulin-Like Growth Factor (IGF)-I-Receptor Binding Sites during In Vitro Transformation of Rat Hepatic Stellate Cells to Myofibroblasts (1996) (41)
Disruption of the latent transforming growth factor-β binding protein-1 gene causes alteration in facial structure and influences TGF-β bioavailability (2008) (40)
Time-resolved immunofluorometric assays with measurement of a europium chelate in solution: application for sensitive determination of fibronectin. (1991) (40)
Expression and function of fibroblast growth factor (FGF) 9 in hepatic stellate cells and its role in toxic liver injury. (2007) (40)
Tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta 1 (TGF beta 1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts. (1993) (40)
Effect of separation conditions on automated isoelectric focusing of carbohydrate-deficient transferrin and other human isotransferrins using the PhastSystem. (1995) (39)
Automated CD61 immunoplatelet analysis of thrombocytopenic samples (2001) (38)
Upregulation of pleiotrophin expression in rat hepatic stellate cells by PDGF and hypoxia: implications for its role in experimental biliary liver fibrogenesis. (2005) (37)
Corticosteroids stimulate selectively transforming growth factor (TGF)-beta receptor type III expression in transdifferentiating hepatic stellate cells. (2004) (37)
Expression of isoforms and splice variants of the latent transforming growth factor beta binding protein (LTBP) in cultured human liver myofibroblasts. (2001) (36)
Maternal factor V Leiden mutation is associated with HELLP syndrome in Caucasian women (2008) (36)
N-Acetyl-L-Cysteine abrogates fibrogenic properties of fibroblasts isolated from Dupuytren's disease by blunting TGF-β signalling (2006) (36)
Effect of pentoxifylline on the fibrogenic functions of cultured rat liver fat-storing cells and myofibroblasts. (1996) (35)
Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca(2+)-dependent interaction with the megalin/gp330 receptor. (2008) (35)
Intracrine signalling of activin A in hepatocytes upregulates connective tissue growth factor (CTGF/CCN2) expression (2008) (35)
Glucocorticoids activate TGF-β induced PAI-1 and CTGF expression in rat hepatocytes (2007) (35)
Transforming growth factor beta 1 gene variants increase transcription and are associated with liver cirrhosis in Chinese. (2008) (35)
Analysis of the transforming growth factor-beta1 (TGF-beta1) codon 25 gene polymorphism by LightCycler-analysis in patients with chronic hepatitis C infection. (2003) (34)
Preventive Effects of Acute Inflammation on Liver Cell Necrosis and Inhibition of Heparan Sulphate Synthesis in Hepatocytes (1986) (34)
Transdifferentiation-dependent expression of α-SMA in hepatic stellate cells does not involve TGF-β pathways leading to coinduction of collagen type I and thrombospondin-2 (2005) (34)
Liver fibrogenesis due to cholestasis is associated with increased Smad7 expression and Smad3 signaling (2006) (34)
TGF-beta-mediated hepatocellular apoptosis by rat and human hepatoma cells and primary rat hepatocytes. (1997) (34)
Hepatocyte-stimulated expression of hepatocyte growth factor (HGF) in cultured rat hepatic stellate cells. (1999) (33)
Interaction of synthetic polynucleotides with small rat liver ribosomal subunits possessing low and highly phosphorylated protein S6. (1980) (33)
Glucocorticoids decrease the bioavailability of TGF-beta which leads to a reduced TGF-beta signaling in hepatic stellate cells. (2004) (33)
Differential expression of keratan sulphate proteoglycans fibromodulin, lumican and aggrecan in normal and fibrotic rat liver (1992) (33)
Hepatic fibrogenesis: the puzzle of interacting cells, fibrogenic cytokines, regulatory loops, and extracellular matrix molecules. (1992) (31)
De novo expression of glutamine synthetase during transformation of hepatic stellate cells into myofibroblast-like cells. (1998) (31)
Inhibitory effect of soluble PDGF-beta receptor in culture-activated hepatic stellate cells. (2004) (30)
Hepatic stellate cell nomenclature. (1996) (30)
Expression and release of the latent transforming growth factor β binding protein by hepatocytes from rat liver (1997) (29)
Immunonephelometric Quantification of Free Haemoglobin (1987) (29)
Analysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults (2004) (29)
Disruption of the latent transforming growth factor-beta binding protein-1 gene causes alteration in facial structure and influences TGF-beta bioavailability. (2008) (29)
Adenoviral-mediated transfer of p53 or retinoblastoma protein blocks cell proliferation and induces apoptosis in culture-activated hepatic stellate cells. (2003) (28)
Insulin-like growth factor signaling pathways in rat hepatic stellate cells: importance for deoxyribonucleic acid synthesis and hepatocyte growth factor production. (1999) (28)
Time-Related Distribution Profiles of Sulfated Glycosaminoglycans in Cells, Cell Surfaces, and Media of Cultured Rat Liver Fat-Storing Cells (1991) (27)
Quantitative monitoring of the mRNA expression pattern of the TGF-β-isoforms (β1, β2, β3) during transdifferentiation of hepatic stellate cells using a newly developed real-time SYBR Green PCR (2002) (27)
The predictive value of serum laminin for portal hypertension in chronic liver diseases. (1988) (27)
Effects of ethanol, acetaldehyde, and lactate on proteoglycan synthesis and proliferation of cultured rat liver fat-storing cells. (1988) (26)
Transforming growth factor-beta1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection. (2005) (26)
Primary biliary cirrhosis is not a clinical condition for increased carbohydrate-deficient transferrin: experience with four independent CDT analysis methods. (2006) (26)
Bidirectional effects of Kupffer cells on hepatocyte proliferation in vitro (1991) (26)
Gene expression of syndecans and betaglycan in isolated rat liver cells (1996) (26)
The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-beta in smooth muscle and hepatic stellate cells. (2006) (25)
Connective tissue growth factor (CTGF/CCN2) in serum is an indicator of fibrogenic progression and malignant transformation in patients with chronic hepatitis B infection. (2013) (25)
Function and metabolism of collagen and other extracellular matrix proteins (1999) (25)
Variation of immunocytochemical expression of transforming growth factor (TGF)-β in hepatocytes in culture and liver slices (1996) (25)
Transdifferentiation-dependent expression of alpha-SMA in hepatic stellate cells does not involve TGF-beta pathways leading to coinduction of collagen type I and thrombospondin-2. (2005) (25)
Comparison of beta2-transferrin and beta-trace protein for detection of cerebrospinal fluid in nasal and ear fluids. (2004) (24)
Activation of proteoglycan synthesis in injured liver--a brief review of molecular and cellular aspects. (1994) (24)
Loss of TGF-beta dependent growth control during HSC transdifferentiation. (2007) (23)
The phosphorylation of liver ribosomal protein S6 during the development of acute hepatic cell injury induced by D‐galactosamine (1977) (23)
Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis. (2009) (23)
CSRP2, TIMP‐1, and SM22α promoter fragments direct hepatic stellate cell‐specific transgene expression in vitro, but not in vivo (2004) (23)
Insulin-Like Growth Factor Signaling Pathways in Rat Hepatic Stellate Cells: Importance for Deoxyribonucleic Acid Synthesis and Hepatocyte Growth Factor Production1. (1999) (23)
Identification of paraxanthine as the most potent caffeine‐derived inhibitor of connective tissue growth factor expression in liver parenchymal cells (2009) (23)
Kidney injury molecule-1 (2019) (23)
Proliferation and transformation of cultured liver fat-storing cells (perisinusoidal lipocytes) under conditions of beta-D-xyloside-induced abrogation of proteoglycan synthesis. (1991) (23)
Subcellular localization of (latent) transforming growth factor beta and the latent TGF-beta binding protein in rat hepatocytes and hepatic stellate cells. (1998) (22)
Hepatocyte-conditioned medium potentiates insulin-like growth factor (IGF) 1 and 2 stimulated DNA synthesis of cultured fat storing cells. (2008) (22)
Improvement of prognostic power of the Child-Pugh classification of liver cirrhosis by hyaluronan. (2003) (22)
Inverse association between serum concentrations of actin-free vitamin D-binding protein and the histopathological extent of fibrogenic liver disease or hepatocellular carcinoma (2009) (22)
The tightrope of therapeutic suppression of active transforming growth factor-beta: high enough to fall deeply? (2003) (22)
Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia. (2008) (21)
Tropoelastin expression is up-regulated during activation of hepatic stellate cells and in the livers of CCl(4)-cirrhotic rats. (2002) (21)
Predictive values of serum N-acetyl-beta-D-glucosaminidase for fibrotic liver disorders--correlation with monoamine oxidase activity. (1982) (21)
Comparative analysis of adenoviral transgene delivery via tail or portal vein into rat liver (2004) (21)
The up-and-down of hepatic stellate cells in tissue injury: apoptosis restores cellular homeostasis. (2001) (21)
Measurement of Connective Tissue Parameters in Serum for Diagnosis and Follow-Up of Liver Fibrosis (1987) (21)
College of American Pathologists (2019) (21)
Serum laminin — Its concentration increases with portal hypertension in cirrhotic liver disease (1986) (20)
N-terminal procollagen peptide and beta 2-microglobulin in synovial fluids from inflammatory and non-inflammatory joint diseases. (1984) (20)
Transforming growth factor beta (TGF-beta) expression in isolated and cultured rat hepatocytes. (1996) (19)
Expression of E-selectin ligand-1 (CFR/ESL-1) on hepatic stellate cells: implications for leukocyte extravasation and liver metastasis. (2009) (19)
Identification of an unconventional nuclear localization signal in human ribosomal protein S2. (2005) (19)
The Prognostic Value of Extracellular Matrix Component Concentrations in Serum During Treatment of Adult Respiratory Distress Syndrome with Extracorporeal CO2 Removal (1991) (19)
Mediators of hepatic fibrogenesis. (1996) (18)
Induction of cell death in activated hepatic stellate cells by targeted gene expression of the thymidine kinase/ganciclovir system. (2004) (18)
Insulin-like growth factors stimulate expression of hepatocyte growth factor but not transforming growth factor beta1 in cultured hepatic stellate cells. (1997) (18)
Transforming growth factors (TGF alpha and TGF beta 1) stimulate chondroitin sulfate and hyaluronate synthesis in cultured rat liver fat storing cells. (1989) (18)
Fibronectin is Synthesized as an Acute Phase Reactant in Rat Hepatocytes (1986) (18)
Influence of fibronectin on the motility of human spermatozoa. (1997) (18)
Connective tissue growth factor reacts as an IL-6/STAT3-regulated hepatic negative acute phase protein. (2011) (17)
Pitfalls in LightCycler diagnosis of the single-nucleotide polymorphism 13.9 kb upstream of the lactase gene that is associated with adult-type hypolactasia. (2007) (17)
Characterization of intracellular pathways leading to coinduction of thrombospondin-1 and TGF-β1 expression in rat hepatic stellate cells (2005) (17)
Fibroblast growth factor 3, a protein with a dual subcellular fate, is interacting with human ribosomal protein S2. (2005) (17)
Transformed fat storing cells inhibit the proliferation of cultured hepatocytes by secretion of transforming growth factor beta. (1990) (17)
Symposium 10: Molecular biology, structure and chemical pathology of connective tissue components (1990) (17)
Developmental changes of proteoglycan synthesis in rat liver and isolated hepatocytes (1985) (17)
A novel proximal -13914G>A base replacement in the vicinity of the common-13910T/C lactase gene variation results in an atypical LightCycler melting curve in testing with the MutaREAL Lactase test. (2007) (17)
[Elevated concentrations of fecal calprotectin in patients with liver cirrhosis]. (2006) (17)
The murine latent transforming growth factor-beta binding protein (Ltbp-1) is alternatively spliced, and maps to a region syntenic to human chromosome 2p21-22. (2003) (17)
Proteochondroitin Sulfate Is the Main Proteoglycan Synthesized in Fetal Hepatocytes (1985) (16)
Cryopreservation of hepatic stellate cells. (2006) (16)
Increased serum xylosyltransferase activity in patients with liver fibrosis. (2009) (16)
Participation of Smad2, Smad3, and Smad4 in Transforming Growth Factor β (TGF-β)-induced Activation of Smad7 (2000) (16)
Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases. (2005) (16)
Fibronectin in human bile fluid for diagnosis of malignant biliary diseases (1996) (16)
Alternative antibody for the detection of CA125 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access® OV Monitor assay on the UniCel® DxI 800 Immunoassay System (2008) (16)
Relation of haemofilter type to venous catheter resistance is crucial for filtration performance and haemocompatibility in CVVH--an in vitro study. (2006) (15)
Quantitative monitoring of the mRNA expression pattern of the TGF-beta-isoforms (beta 1, beta 2, beta 3) during transdifferentiation of hepatic stellate cells using a newly developed real-time SYBR Green PCR. (2002) (15)
High prevalence of increased trisialotransferrin concentrations in patients with anorexia nervosa: implications for determination of carbohydrate-deficient transferrin. (2007) (15)
Age-related decrease in the activity of UDP-xylose:Core protein xylosyltransferase in rat costal cartilage (1982) (15)
Higher levels of aminoterminal type III procollagen peptide, and laminin in alcoholic in nonalcoholic cirrhosis of equal severity (1992) (15)
TGF-β up-regulates serum response factor in activated hepatic stellate cells (2007) (15)
Variable expression of cystatin C in cultured trans-differentiating rat hepatic stellate cells. (2006) (15)
Expression of different isoforms of TGF-beta and the latent TGF-beta binding protein (LTBP) by rat Kupffer cells. (1998) (14)
A cascade-mechanism of fat storing cell activation forms the basis of the fibrogenic reaction of the liver. (1995) (14)
Atypical melting curve resulting from genetic variation in the 3' untranslated region at position 20218 in the prothrombin gene analyzed with the LightCycler factor II (prothrombin) G20210A assay. (2005) (13)
Albumin and hydroxyethyl starch 130 kDa/0.4 improve filter clearance and haemocompatibility in haemo- and plasmafiltration--an in vitro study. (2005) (13)
The relation between hepatocellular damage and activation of fat-storing cell proliferation in vitro (1994) (13)
Expression of cytosolic and membrane associated tissue transglutaminase in rat hepatic stellate cells and its upregulation during transdifferentiation to myofibroblasts in culture. (2004) (13)
Hepatic proteoglycans--a brief survey of their pathobiochemical implications. (1983) (13)
Questioning the role of actinfree Gc-Globulin as actin scavenger in neurodegenerative central nervous system disease: relationship to S-100B levels and blood-brain barrier function. (2009) (13)
Characterization of hepatocyte-derived mitogenic activity on hepatic stellate cells. (2000) (13)
Serum concentrations of N-terminal propeptide of type III procollagen and laminin in the outflow of fibrotic livers compared with liver-distal regions. (1986) (13)
Biosynthesis of small proteoglycans by hepatic lipocytes in primary culture (1989) (12)
The state of ribosomal protein phosphorylation during thioacetamide-induced liver injury. (1978) (12)
CDTect-RIA and CDTect-EIA for determination of serum carbohydrate-deficient transferrin compared. (1998) (12)
An unusual melting curve profile in LightCycler multiplex genotyping of the hemochromatosis H63D/C282Y gene mutations. (2001) (12)
Validity of Monoamine Oxidase in Serum for Diagnosis of Liver Cirrhosis: Estimation of Predictive Values, Sensitivities and Specificities (1982) (12)
The Sequence of Changes in the Biosynthesis of Sulfated Glycosaminoglycans in Acute, Experimental Liver Disease (1982) (11)
Argininosuccinate lyase deficiency (ASL) and carbohydrate-deficient transferrin (CDT): experience with four independent CDT analysis methods--misleading results given by the %CDT TIA assay. (2006) (11)
Divergence of TGFβ signaling in activated hepatic stellate cells downstream from Smad2 phosphorylation (2002) (11)
Cytokine regulation of hyaluronate production by human Tenon's capsule fibroblasts. (2000) (11)
Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-L-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells. (2005) (11)
Alternative antibody for the detection of CA15-3 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access® BR Monitor assay on the UniCel® DxI 800 Immunoassay System (2008) (10)
Plasma Pyridoxal 5'-Phosphate Concentrations in Relation to Apo-Aminotransferase Levels in Normal, Uraemic, and Post-Myocardial Infarct Sera (1985) (10)
Laser nephelometric quantitation of fibronectin (cold-insoluble globulin) in human cerebrospinal fluid and seminal plasma. (1981) (10)
Pharmacological application of caffeine inhibits TGF-b-stimulated connective tissue growth factor expression in hepatocytes via PPAR c and SMAD 2 / 3-dependent pathways q (2008) (10)
Evaluation of serum aminoterminal procollagen type III propeptide as an index of portal hypertension and esophageal varices in chronic liver diseases. (1988) (10)
Standardized flow cytometric method for the accurate determination of platelet counts in patients with severe thrombocytopenia. (2000) (10)
Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases (2006) (9)
Alternative antibody for the detection of CA19-9 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access® GI Monitor assay on the UniCel® DxI 800 Immunoassay System (2008) (9)
Concentration of laminin in serum related to the degree of esophageal varices in fibrotic liver diseases. (1988) (9)
Evaluation of the Assay for Serum Monoamine Oxidase – an Index of Hepatic Fibrosis (1980) (8)
Effects of murine recombinant interferon-gamma on rat liver fat storing cell proliferation, cluster formation and proteoglycan synthesis. (1990) (8)
The chemical morphology of extracellular matrix in experimental rat liver fibrosis resembles that of normal developing connective tissue (2004) (8)
LightCycler-analysis of the Transforming Growth Factor-beta1 Codon 25 Gene Polymorphism in German Patients with Chronic Hepatitis C Infection (2004) (8)
PDGF-BB Induces Expression of LTBP-1 but not TGF-β1 in a Rat Cirrhotic Fat Storing Cell Line (2003) (8)
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The phosphorylation of rat liver ribosomes following administration of dimethylnitrosamine. (1978) (7)
Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells (2009) (7)
Hepatocyte-stimulated expression of hepatocyte growth factor (HGF) in cultured rat hepatic stellate cells (1998) (7)
Technical evaluation of the Beckman Coulter OV-Monitor (CA 125 antigen) immunoassay (2006) (7)
Cytokines in liver injury and repair (2002) (7)
[Potential novel biomarkers for monitoring the fibrogenic process in livers]. (2008) (7)
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Binding of chondroitin sulfate, dermatan sulfate and fat-storing cell-derived proteoglycans to rat hepatocytes. (1987) (6)
Two sensitive time-resolved fluoroimmunoassays for cellular fibronectin. (1995) (6)
Evaluation of serum percent trisialotransferrin as potential predictive biomarker of hepatocellular dedifferentiation in chronic liver disease. (2009) (6)
Immunoturbidimetric measurement of cold insoluble globulin with reference to a laser nephelometric assay. (1981) (6)
The Diagnostic Potential of the Combined Determination of Serum Monoamine Oxidase and N-Acetyl-β-D-Glucosaminidase for Fibroproliferative Liver Diseases (1983) (6)
TGF-beta up-regulates serum response factor in activated hepatic stellate cells. (2007) (6)
Questioning the reliability of p-nitrophenyl-beta-D-xyloside as probe to study the metabolic effects of abrogated proteoglycan synthesis in cultured cells. (1991) (6)
Amidolytic and Immuno-Nephelometric Determination of α1-Proteinase Inhibitor and α2-Macroglobulin in Serum with Calculation of Specific Inhibitor Activities in Health and Disease (1984) (6)
Evaluation of a Fully Mechanized Enzymatic Kinetic Determination of Sialic Acid (1985) (6)
The synthesis of glycosaminoglycans in isolated hepatocytes during experimental liver fibrogenesis. (2008) (6)
Follow‐up of the serum levels of extracellular matrix components in acute and chronic pancreatitis (1990) (6)
Stimulated synthesis of glycosaminoglycans in suspension cultures of hepatocytes from subacutely injured livers. (1982) (6)
Treatment of rat hepatocytes with transforming growth factor β1 increases their mitogenic activity for cultured fat storing cells (1995) (6)
Intraperitoneal application of caffeine prevents D-galactosamine-induced hepatic expression of connective tissue growth factor (CTGF/CCN2) in the rat. (2009) (6)
Influence of Anti-Inflammatory Drugs on Connective Tissue Metabolism (1977) (5)
Secreted cysteine-rich FGF receptor derives from posttranslational processing by furin-like prohormone convertases. (2009) (5)
Evaluation of hepatotropic targeting properties of allogenic and xenogenic erythrocyte ghosts in normal and liver‐injured rats (2007) (5)
Higher levels of serum aminoterminal type III procollagen peptide, and laminin in alcoholic than in nonalcoholic cirrhosis of equal severity. (1992) (5)
Metabolic and Structural Studies on Serum- and Liver-Glycosaminoglycans in Normal and Liver-injured Rats (1980) (5)
Laminin and aminoterminal propeptide of type III procollagen in seminal plasma from fertile and vasectomized men (2009) (5)
Estimation of the Production Rates of Serum Aminoterminal Propeptide of Type III Procollagen and Laminin in Human Fibrotic Liver (1987) (5)
The synthesis of glycosaminoglycans in aging rat liver. A brief note (1979) (5)
Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor (CTGF/CCN2) expression in hepatocytes via PPARγ and Smad2/3-dependent pathways (2008) (4)
Identification of the tRNA-binding sites on rat liver ribosomes by affinity labeling (2004) (4)
Comparison of three commercial assays for the measurement of 17α-hydroxyprogesterone (17α-OHPR): limitations of the quality control system (2004) (4)
Practical Implications of Coexistent Different Technologies in Clinical Chemical Laboratories. Solid Phase Chemistry and Conventional Analysis (1991) (4)
Determination of protein synthesis elongation factor activity in liver biopsy specimens from normal and cirrhotic rats. (1977) (4)
Society of Hair Testing (2019) (4)
Changes in the Catalytic Activities of Proteoglycan-Degrading Lysosomal Enzymes in Parenchymal and Non-Parenchymal Liver Cells and in Serum During the Development of Experimental Liver Fibrosis (1983) (4)
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Amidolytic and immuno-nephelometric determination of alpha 1-proteinase inhibitor and alpha 2-macroglobulin in serum with calculation of specific inhibitor activities in health and disease. (1984) (3)
Beta-D-xyloside induced modulations of glycosaminoglycans, proliferation, and cytoskeletal organization of rat liver myofibroblast-like cells (transformed fat storing cells). (1991) (3)
Comparison of three commercial assays for the measurement of 17alpha-hydroxyprogesterone (17alpha-OHPR): limitations of the quality control system. (2004) (3)
Determination of UDP-xylose: Core protein xylosyl transferase in human serum and age-dependent decrease of activity in cartilage (1982) (3)
with progression of liver fibrosis in Caucasians with chronic hepatitis C infection (2005) (3)
Synthesis of Hepatic Glycosaminoglycans in the Early Stages of Galactosamine Hepatitis: A Rapid Decline of Heparan Sulfate is Followed by Elevation of Chondroitin Sulfate and Dermatan Sulfate (1981) (3)
The synthesis of total and specific glycosaminoglycans during development of experimental liver cirrhosis (1977) (3)
Effects of agents interacting with connective tissue. (1979) (3)
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Amino-terminal propeptides of type III procollagen in seminal fluid. (1984) (3)
[Experimental studies of the historheology of the liver capsule (author's transl)]. (1977) (2)
005 Time-resolved immunoassay for cellbound antigens in the solid phase status using cultured cells (1992) (2)
Aminoterminal Propeptides of Type III Procollagen in Human Cerebrospinal Fluid (1984) (2)
Improved Method for Isolating Cell (2005) (2)
International Federation of Clinical Chemistry and Laboratory Medicine (2019) (2)
Insulin-like growth factor signaling pathways in rat hepatic stellate cells: Importance for DNA synthesis and hepatocyte growth factor production (2000) (2)
Molecular and cell biology of liver fibrogenesis : proceedings of the International Falk Symposium held in Marburg, Germany, 22-23 January 1992 (1992) (2)
Ribosomal Protein Modifications in Liver Injury: Effect of Carbon Tetrachloride and Extrahepatic Cholestasis on Protein Phosphorylation (1980) (2)
Influence of reagent composition on atypical pseudocholinesterase activity measurement: comparison of a manual and an automated method and implications for routine. (1992) (2)
Cytokine regulation of hyaluronate production by human Tenon’s capsule fibroblasts (2000) (2)
Laser Nephelometric Determination of Glycosaminoglycans — Method and Application (1983) (2)
Effect of n-butyrate on the synthesis of sulfated glycosaminoglycans and hyaluronate by rat liver fat-storing cells (Ito cells). (1988) (2)
Feedback mechanisms between alpha 2M and TGF beta 1 reduce extracellular matrix synthesis of liver fat-storing cells. (1994) (2)
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An evaluation of a monoclonal antibody based sandwich radioimmunoassay for the col 1 3 amino terminal propeptide of type iii procollagen in serum (1990) (2)
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Synthesis in Vitro of Glycosaminoglycans in Regenerating Rat Liver (1981) (2)
On the biomechanical function of the liver capsule (1977) (2)
Continuous enrichment of albumin in relation to globulins in plasma. (1982) (2)
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Effects of cyclic adenosine 3':5'-monophosphate and cyclic guanosine 3':5'-monophosphate on liver proteoglycan synthesis. (1981) (2)
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[Histomechanical studies on test specimens from hyaline cartilage under compressive loading with regard to rheology (author's transl)]. (1978) (1)
Pseudocholinesterase (2019) (1)
Transforming growth factor-β (TGF-β)-receptor gene expression in cultured rat hepatocytes (1996) (1)
Rapid FSAP Genotyping of the E393Q (Marburg II) and G534E (Marburg I) Polymorphisms on the LightCycler in a Multiplex PCR Using Two Fluorescently Labeled Probe Sets (2008) (1)
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[The use of laser nephelometry for the determination and computer-assisted calculation of the fibronectin concentration in various body fluids (author's transl)]. (1980) (1)
Connective tissue growth factor ( CTGF / CCN 2 ) in serum is an indicator of fi brogenic progression and malignant transformation in patients with chronic hepatitis B infection (2013) (1)
Elevated concentrations of 15-deoxy-Δ12,14-Prostaglandin J2 in chronic liver disease propose therapeutic trials with PPARgamma inducing drugs (2009) (1)
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Soluble Endoglin modulates TGF-β1 mediated signaling in isolated hepatocytes (2008) (1)
Serum laminin and procollagen type III propeptide in patients with respiratory distress syndrome: Potentially useful markers of therapy success (1988) (1)
Hepatic fibrosis in patients with chronic hepatitis B virus infection can be partially reversed by IFN-γ (2005) (1)
Increased laminin concentrations in serum in hyperthyroidism. (1989) (1)
Endothelin-receptor antagonist/N-acetylcysteine combination in type 1 hepatorenal syndrome (2009) (1)
Identi ¢ cation of paraxanthine as themost potent ca ¡ eine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells (2009) (1)
The role of Smad signaling in bile duct ligation induced fibrogenesis in rat (2004) (1)
Biochemical parameters of liver fibrosis: Evaluation of the monoamine oxidase assay in serum (1980) (1)
Two-Dimensional Electrophoretic Analysis of Ribosomal Proteins from Chronically Injured Liver (1979) (1)
IFN-γ Abrogates Profibrogenic TGF-β Signaling in the Liver by Targeting the Expression of Pathway-Restricted and Inhibitory Smads (2005) (1)
Homeostasis Model Assessment (2019) (1)
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Inflammation-induced synthesis of proteoheparan sulfate: A novel acute-phase reactant in rat hepatocytes (1987) (1)
YB-1 mediates IFN-γ dependent regulation of TGF-β responsive genes, thereby providing antifibrotic effects (2004) (1)
Expression of pleiotrophin and its receptors in hepatic cells and in activated hepatic stellate cells (HSCs)– Pleiotrophin in hepatic stellate cells (2004) (1)
Transformation of fat storing cells is associated with an enhanced synthesis of proteoglycans and cytokines (1990) (1)
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Analysis of transforming growth factors as fibrogenic mediators in the liver : cellular origins, effects on target cell proliferation/transformation and matrix proteoglycans synthesis (1990) (0)
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Synthesis in Vitro of Glycosaminogl ycans in Regenerating Rat Liver (1981) (0)
Influence of Glucocorticoids on TGF-β-Smad Signaling in Activated Hepatic Stellate Cells (2005) (0)
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Glucocorticoids reduce TGF-β Isoform 1, 2, 3 mRNA expression, TGF-β secretion and signaling in Hepatic Stellate Cells (2004) (0)
51 GENE POLYMORPHISMS WITHIN THE CODING REGION OF TGF-BETA1 AFFECT CELLULAR SYNTHESIS, SECRETION AND PROCESSING OF TGF-BETA1 VIA THE LATENT TGF-BETA BINDING PROTEIN-1 (LTBP-1) (2008) (0)
Expression of E-selectin and its ligand ESL–1 in rat hepatic stellate cells (HSC): implications for leukocyte extravasation and liver metastasis (2007) (0)
Serumprotein-Labilitätsreaktionen (2019) (0)
Expression and deposition of the latent TGFβ complex in trans-differentiating cultured hepatic stellate cells (HSC) under influence of cytokines (2000) (0)
Potential diagnostic value of serum proteome profiling with MALDI-TOF-MS and the suggested serum markers sFlt-1, PlGF and Endoglin in patients with preeclampsia (2007) (0)
Is there a specific fibrogenic effect in alcholic human liver cirrhosis (1990) (0)
The megalin/gp330 receptor is involved in the capability of hepatic stellate cells to bind and internalize vitamin D binding protein (Gc-globulin) (2008) (0)
Index, insulinogener (2019) (0)
Apoenzyme contents of alanine-aminotransferase and aspartate-aminotransferase, and pyridoxal-5′-phosphate levels under normal and pathologie conditions (1984) (0)
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Elevated concentrations of15-deoxy-D-prostaglandin J2 in chronic liver disease propose therapeutic trialswith peroxisomeproliferator activated receptor c-inducing drugs (2009) (0)
Antigen-presenting function of rat hepatic stellate cells (2007) (0)
FIGLU-Test (2019) (0)
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Insulin-like growth factor signalling pathways inrat hepatic stellate cells are important for DNA synthesis and hepatocyte growth factor production (1999) (0)
Characterization of TGF-β-dependent signaling-pathways for CTGF/CCN2 expression in hepatocytes of normal and injured livers (2007) (0)
Disruption of TGF-beta signal transduction in hepatocellular carcinoma by overexpression of Smad7 (2002) (0)
Bone morphogenetic protein–7 (BMP–7), a neglected player in hepatic fibrosis? (2007) (0)
Comparison of (cid:3) 2 -Transferrin and (cid:3) -Trace Protein for Detection of Cerebrospinal Fluid in Nasal and Ear Fluids, (2004) (0)
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Transforming Growth Factor-β induced Expression of Serum Response Factor in Hepatic Stellate Cells during Liver Fibrogenesis (2007) (0)
Stromal–Epithelial Cell Interactions in the Mechanisms of Hepatocyte Injury, Liver Cell Regeneration and Fibrogenesis (1994) (0)
Gallensäurepool (2019) (0)
Polymorphisms of transforming growth factor-β1 (TGF-β1) gene related to progression of liver fibrosis (2001) (0)
RESULTS OF THE MULTICENTRIC EVALUATION OF A NEW SYSTEM FOR PHOTOMETRIC DETERMINATION OF COAGULATION PARAMETERS (1987) (0)
A Serum Proteom Approach to Diagnose Liver Fibrosis/Cirrhosis – Preliminary Results (2005) (0)
Microarray Gene Expression Profiling of Fibroblast Growth Factor Ligands, their Receptors and Antagonists in Rat Liver Cells (2005) (0)
Mendel, Gregor Johann (2019) (0)
888 The Y-box protein YB-1 suppresses collagen expression in hepatic stellate cells via upregulation of SMAD7 (2003) (0)
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PLGA-Nanospheres: Delivery tools for the treatment of liver fibrosis (2006) (0)
Differential mrna expression levels of TGFβ and LTBP-isoforms during transformation of cultured rat liver hepatic stellate cells to myofibroblasts (2000) (0)
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The impact of the reactive oxygen species scavenger N-acetyl-L-cysteine for PDGF-BB signaling in cultured hepatic stellate cells (2006) (0)
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Autocrine regulation of myofibroblast-like cells via polypeptide growth factors, proteoglycans and α2-macroglobulin (1991) (0)
Fettleber-Index (2019) (0)
Wai-Index (2019) (0)
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Zur experimentellen Rheologie des Leberparenchyms - Experimental rheology of the liver parenchyma (1977) (0)
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Connective Tissue Metabolism in Liver Diseases and its Relevance in Clinical-Chemical Diagnosis (1982) (0)
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Gallepigmente (2019) (0)
Expression of smooth muscle cell markers in activated hepatic stellate cells is connected to MAP kinase regulated transcription levels of serum response factor (SRF) (2009) (0)
Western blot (2019) (0)
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Murine recombinant interferon-gamma acts as a growth promoter for rat liver fat storing cells in vitro (1989) (0)
Role of connective tissue growth factor (CTGF/CCN2) concentrations in serum as indicator for the advancement of fibrosis and neoplastic transformation of cirrhosis in patients with chronic liver disease (2012) (0)
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New pathogenetic concepts of liver fibrosis with options for therapy and diagnostics (2007) (0)
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Identification of the N-Acetylcysteine Sensitive Receptor Endoglin in Hepatic Stellate Cells (2005) (0)
On the diagnostic potential of fibronectin in human bile fluid (1994) (0)
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Antisepsis (2019) (0)
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Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor (cid:98) 1 in Cultured Hepatic Stellate Cells* (1997) (0)
Learning more about the role of Latent transforming growth factor-β binding protein–1 (LTBP–1) – a knockout approach in mice (2006) (0)
Three-dimensional Spheroidal Coculture Model of Activated Hepatic Stellate Cells and Endothelial Cells (2005) (0)
Alanin-Aminotransaminase (2019) (0)
Interactions of fat-storing cells with hepatocyte plasma membranes and pericellular matrix (1990) (0)
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Forum of the European Societies of Clinical Chemistry and Laboratory Medicine (2019) (0)
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Identification of Id1 as target gene of profibrogenic TGF-β family signaling during transdifferentiation of hepatic stellate cells (2004) (0)
Heller, Johann Florian (2019) (0)
Shine- und Lal-Index (2019) (0)
Mullis, Kary Banks (2019) (0)
Antagonization of TIMP–1 Induces Apoptosis in Activated Hepatic Stellate Cells (2005) (0)
The absence of latent transforming growth factor-beta binding protein–1 (LTBP–1) inhibits TGF-beta secretion (2008) (0)
Wöhlk-Probe (2019) (0)
The guanine exchange factor Net1 is induced upon TGF-beta stimulation during transdifferentiation of hepatic stellate cells (2004) (0)
Fibrosekenngrößen (2019) (0)
Leber-Eisen-Index (2019) (0)
Synergistic effects of Platelet-derived growth factor-BB and Transforming growth factor-β1 on profibrogenic activities in hepatic stellate cells (2008) (0)
Transsudat (2019) (0)
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Upregulation of smooth muscle cell markers in activated hepatic stellate cells is mediated by serum response factor (2007) (0)
Inhibitory effect of Tumor Necrosis Factor α, Interleukin 2, and Interferon γ on CTGF expression in cultured rat hepatocytes (2009) (0)
JNK dependent regulation of TGF-β target genes in hepatic stellate cells (2008) (0)
MEK, a switchman for cell type-specific regulation of connective tissue growth factor in primary liver cells (2007) (0)
Northern blot (2019) (0)
Expression and TGF-beta modulation of connective tissue growth factor (CTGF) in hepatic stellate cells and hepatocytes (2006) (0)
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Acute phase response of liver proteoheparan sulfate during inflammation (1986) (0)
Fig. 1. Concentrations of laminin in senim from the cubital vein of patients with fibrotic liver diseaseshaving differentstages of esophagealvailces (2004) (0)
Determination of the activity of liver fibrogenic factors (1988) (0)
Identification of connective tissue growth factor as a hepatic negative acute phase protein (2009) (0)
Probenidentifikation (2019) (0)
Transcriptional Targeting of Activated Hepatic Stellate Cells by Modular Promoter Fragments (2008) (0)
New role for the hepatocyte during TGF-β mediated liver fibrogenesis (2006) (0)
Bence Jones, Henry (2019) (0)
The N-Acetylcysteine sensitive TGF-β receptor endoglin shows a defined expression pattern in liver cells (2005) (0)
The knockout of latent transforming growth factor-β binding protein–1 (LTBP–1) affects the fibrogenic potential in mice liver (2007) (0)
Regulated expression of the Anaplastic Lymphoma Kinase (ALK) in cultured rat hepatic stellate cells during transdifferentiation into myofibroblasts (2005) (0)
Hepatic stellate cells become susceptible to fas-ligand induced apoptosis during transformation to myofibroblasts (1998) (0)
Berthelot-Reaktion (2019) (0)
Selective determination of serum N-terminal procollagen-III-peptide and laminin in liver-proximal and -distal regions of the circulation and correlation with the portal venous pressure (1986) (0)
UDP-Glukuronyltransferase (2019) (0)
Heidelberger-Kurve (2019) (0)
Expressive changes in TGFβ1 signaling during activation of hepaticstellate cells (2000) (0)
LIM-domain protein CRP2 is upregulated in activated hepatic stellate cells by TGFβ1 (2005) (0)
Studies on the functional role of proteoglycans in fat storing cell activation/transformation (1991) (0)
Thrombospondin (TSP) expression in transdifferentiating hepatic stellate cells (HSC) from rat liver: Involvement in the activation of latent TGF-beta? (2003) (0)
Hepcidin (2019) (0)
Skeggs, Leonard Tucker Jr. (2019) (0)
The effect of trifluoperazine on the phosphorylation of ribosomal small subunit protein S6 in D-galactosamine-injured and normal rat liver. (1983) (0)
Glykoprotein, α1-saures (2019) (0)
Transferrinsättigung (2019) (0)
Scavenging endogenous PDGF B-chain by adenovirus-mediated PDGFbetaR-Fc gene transfer potentially inhibits HSC activation and attenuates liver fibrosis (2004) (0)
Cystatin C is expressed in hepatic stellate cells (HSC) and upregulated during transdifferentiation to myofibroblasts (MFB) (2005) (0)
Fehling-Probe (2019) (0)
Tauroursodeoxycholic acid shows converse effects on TGF-β-Smad 3 signaling in liver cells (2006) (0)
1277 PDGF-BB induces thrombospondin-1 expression in a SRC-dependent manner leading to activation of latent TGF-β in hepatic stellate cells (2003) (0)
Retraction. "Intraperitoneal application of caffeine prevents D-galactosamine induced hepatic expression of connective tissue growth factor (CTGF/CCN2) in the rat" [JHEPAT 50 (2009) 1053-1055]. (2010) (0)
Colombi-Index (2019) (0)
Analysis of antigen-presenting functionality of rat hepatic stellate cells (2009) (0)
Gene polymorphisms in the secretory signal peptide of TGF-β1 affect the cellular synthesis, secretion and processing of TGF-β1 and secretion is modulated by the latent TGF-β binding protein-1 (LTBP-1) and furin protease (2007) (0)
Expression of the cysteine protease inhibitor cystatin C in hepatic stellate cells is upregulated during transdifferentiation (2005) (0)
Therapeutic application of dominant-negative PDGF beta-receptor in liver fibrosis (2004) (0)
Transcriptional activity of Serum Response Factor is mediated by the RhoA/Rho kinase pathway during HSC differentiation and influences expression of Smooth Muscle Cell marker genes (2008) (0)
C-reaktives Protein, ultrasensitiv (2019) (0)
Diversity of TGF-β-signaling in rat hepatic stellate cells and in myofibroblasts (2006) (0)
Gene Expression Profiling of Fibroblast Growth Factor Ligands and their Receptors in Rat Hepatic Stellate Cells (HSC) and In In Vitro Transdifferentiated Myofibroblasts (MFB) (2006) (0)
Cryopreservation of Hepatic Stellate Cells: A Valid Method for Banking Progenitor Cells of Liver Fibrogenesis (2005) (0)
Transforming Growth Factor β (2019) (0)
Synergistic action of PDGF on TGF-β stimulated gene expression in cultured rat hepatic stellate cells: Inhibition by NAC (N-acetyl-L-cystein) (2003) (0)
Effects of N-acetylcysteine and L-Cysteine on TGF-beta Signaling in Culture-activated Hepatic Stellate Cells (2004) (0)
Bial-Probe (2019) (0)
Analysis of transforming growth factor-β1 gene polymorphisms in patients with Hepatitis C infection (2006) (0)
The „accessory“ TGF-β pathway is not obligatory to ALK1 expressing cells (2006) (0)
α2-HS-Glykoprotein (2019) (0)
Inhibitory effects of glucocorticoids on TGF-β-Smad 3 signalling are activated by tauroursodeoxycholic acid in hepatic stellate cells (2006) (0)
Genomic organization of the rat Smad7 gene: Identification and functional characterization of the Smad binding element responsible for negative feedback regulation of TGFβ signaling (2000) (0)
Transforming growth factors (TGFa and TGFB) are potent fibrogenic mediators stimulating rat liver fat storing cell proliferation and proteoglycan-hyaluronate synthesis (1989) (0)
The role of proteoglycans in the development of liver fibrosis (1990) (0)
Venter, Craig John (2019) (0)
Gmelin-Probe (2019) (0)
Comparative determination of selected hemostascological parameters in a case of severe hypofibrinogenemia caused by snakebite of Deinagkistrodon Acutus using the electromechanical clot detection and optical end point analysis (2009) (0)
Stress-induced activation of TGF-β and activin A signaling in hepatocytes leads to early expression of connective tissue growth factor (CTGF/CCN2) (2008) (0)
Retinol-bindendes Protein (2019) (0)
Developmental and Age-Dependent Changes of Proteoglycan Metabolism in Normal and Experimentally Injured Liver and the Effects of Drugs (1986) (0)
Glutamat-Dehydrogenase (2019) (0)
Crosstalk between glucocorticoid receptor bound corticosteroids and the TGF-β-Smad 3 pathway in liver cells (2006) (0)
Predictive values of monoamine oxidase and N-Acetyl-β-d-Glucosaminidase in serum for diagnosis of liver cirrhosis and fibrosis (1982) (0)
Contamination of urine samples by test-strip measurement? (1989) (0)
Heidelberger, Michael (2019) (0)
[What is the importance today of determining blood sedimentation rate in addition to measuring so-called acute phase proteins?]. (1992) (0)
Corticosteroids antagonize TGF-β-Smad signaling in activated hepatic stellate cells (2005) (0)
Engvall, Eva (2019) (0)

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